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https://www.readbyqxmd.com/read/29277373/exertional-tolerance-assessments-after-mild-traumatic-brain-injury-a-systematic-review
#1
REVIEW
Catherine Quatman-Yates, Anna Bailes, Sara Constand, Mary Claire Sroka, Katharine Nissen, Brad Kurowski, Jason Hugentobler
OBJECTIVE: The objective of this study was to review the literature to identify and summarize strategies for evaluating responses to physical exertion after mild traumatic brain injury (mTBI) for clinical and research purposes. DATA SOURCES: PubMed and EBSCOHost through December 31, 2016. STUDY SELECTION: Two independent reviewers selected studies based on the following criteria: 1) inclusion of participants with mTBI/concussion, 2) use of a measurement of physiological or psychosomatic response to exertion, 3) a repeatable description of the exertion protocol was provided, 4) a sample of at least 10 participants with a mean age between 8-65 years, and 5) the article was in English...
December 22, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29239280/perceived-injustice-and-its-correlates-after-mild-traumatic-brain-injury
#2
Grant L Iverson, Douglas P Terry, Justin E Karr, William Panenka, Noah D Silverberg
Perceived injustice is a belief that one has been treated unfairly, disrespectfully, and is suffering unnecessarily as a result of another person's actions. Perceived injustice predicts chronic disability after musculoskeletal injury, but to our knowledge, has not been empirically studied in people with mild traumatic brain injuries (MTBIs). We examined perceived injustice and its correlates in patients who were slow to recover from MTBI. Patients (N=102) were recruited from four concussion clinics. The sample was on average 41...
December 14, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29239267/a-retrospective-study-of-predictors-of-return-to-duty-vs-medical-retirement-in-an-active-duty-military-population-with-blast-related-mild-traumatic-brain-injury
#3
Philip A Cook, Thomas M Johnson, Suzanne G Martin, Philip R Gerhman, Seema Bhatnagar, James C Gee
Traumatic Brain Injury (TBI), has been described as the "signature injury" of the Global War on Terror. Explosive blast TBI has become a leading cause of injury as a result of the widespread use of improvised explosive devices in Iraq and Afghanistan. We present a retrospective cross-sectional study of patients with blast-related mild TBI (N=303) seen at the Intrepid Spirit Concussion Recovery Center at Naval Medical Center Camp Lejeune. The objective was to predict outcomes of return to duty (RTD) vs. medical retirement via medical evaluation board (MEB), based on brain imaging, neuropsychological data and history of mTBI...
December 14, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29188026/is-temperature-an-important-variable-in-recovery-after-mild-traumatic-brain-injury
#4
REVIEW
Coleen M Atkins, Helen M Bramlett, W Dalton Dietrich
With nearly 42 million mild traumatic brain injuries (mTBIs) occurring worldwide every year, understanding the factors that may adversely influence recovery after mTBI is important for developing guidelines in mTBI management. Extensive clinical evidence exists documenting the detrimental effects of elevated temperature levels on recovery after moderate to severe TBI. However, whether elevated temperature alters recovery after mTBI or concussion is an active area of investigation. Individuals engaged in exercise and competitive sports regularly experience body and brain temperature increases to hyperthermic levels and these temperature increases are prolonged in hot and humid ambient environments...
2017: F1000Research
https://www.readbyqxmd.com/read/29180620/quantitative-measurement-of-post-concussion-syndrome-using-electrovestibulography
#5
Abdelbaset Suleiman, Brian Lithgow, Zeinab Dastghieb, Behzad Mansouri, Zahra Moussavi
In this study, a noninvasive quantitative measure was used to identify short and long term post-concussion syndrome (PCS) both from each other and from healthy control populations. We used Electrovestibulography (EVestG) for detecting neurophysiological PCS consequent to a mild traumatic brain injury (mTBI) in both short-term (N = 8) and long-term (N = 30) (beyond the normal recovery period) symptomatic individuals. Peripheral, spontaneously evoked vestibuloacoustic signals incorporating - and modulated by - brainstem responses were recorded using EVestG, while individuals were stationary (no movement stimulus)...
November 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29172011/therapy-and-rehabilitation-of-mild-brain-injury-concussion-systematic-review
#6
Roger E Thomas, Jorge Alves, Marcus M Vaska Mlis, Rosana Magalhaes
BACKGROUND: Assessment of therapies for the key consequences of mild traumatic brain injury (mTBI)/concussion is required. OBJECTIVE: Identify all RCTs of mTBI/concussion therapy, risks of bias, and therapies with significant positive results. METHODS: 17 electronic, 9 grey-literature databases searched without language/date restrictions; independent assessment of 1450 Abstracts/titles, 141 fulltext articles, 14 included RCTs. RESULTS: Four RCTs used American Congress of Rehabilitation TBI definition, others used unique definitions...
2017: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29168451/intraindividual-cognitive-variability-an-examination-of-anam4-tbi-mil-simple-reaction-time-data-from-service-members-with-and-without-mild-traumatic-brain-injury
#7
Wesley R Cole, Emma Gregory, Jacques P Arrieux, F Jay Haran
OBJECTIVES: The Automated Neuropsychological Assessment Metrics 4 TBI-MIL (ANAM4) is a computerized cognitive test often used in post-concussion assessments with U.S. service members (SMs). However, existing evidence remains mixed regarding ANAM4's ability to identify cognitive issues following mild traumatic brain injury (mTBI). Studies typically examine ANAM4 using standardized scores and/ or comparisons to a baseline. A more fine-grained approach involves examining inconsistency within an individual's performance (i...
November 23, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29157855/imaging-the-role-of-myelin-in-concussion
#8
REVIEW
Alexander Mark Weber, Carlos Torres, Alexander Rauscher
Myelin water imaging (MWI) provides mild traumatic brain injury (mTBI) researchers with a specific myelin biomarker and helps to further elucidate microstructural and microarchitectural changes of white matter after mTBI. Improvement of scanner hardware and software with the implementation of MWI across scanner platforms will likely result in increased research regarding the role of myelin in traumatic brain injury (TBI). Future research should include detailed investigation of myelin between 2 weeks and 2 months after injury, the use of MWI in moderate and severe TBI, and investigation of the role of myelin in chronic TBI...
February 2018: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/29157850/conventional-computed-tomography-and-magnetic-resonance-in-brain-concussion
#9
REVIEW
Juan Nicolas Useche, Sonia Bermudez
Conventional neuroimaging is still the mainstay in the assessment of the acute, follow-up, and chronic settings of concussion and mild traumatic brain injury (mTBI). Computed tomography (CT) is preferred for the initial assessment of acute mTBI, repeat evaluation in acute mTBI with neurologic deterioration, and cautious use in children with mTBI. Clinical rules have been developed to identify pediatric and adult patients with mTBI who can safely forego CT. Magnetic resonance (MR) imaging is mostly used in patients with acute mTBI when initial or follow-up CT is normal and there are persistent neurologic findings and in subacute or chronic mTBI...
February 2018: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/29108477/hyperthermia-and-mild-traumatic-brain-injury-effects-on-inflammation-and-the-cerebral-vasculature
#10
Jessie Truettner, Helen M Bramlett, W Dalton Dietrich
Mild traumatic brain injury (mTBI) or concussion represents the majority of TBIs brain trauma in the United States. The pathophysiology of mTBI is complex and may include both focal and diffuse injury patterns. In addition to altered circuit dysfunction and diffuse traumatic axonal injury (DTAI), chronic neuroinflammation has also been implicated in the pathophysiology of mTBI. Recently, our laboratory has reported the detrimental effects of mild hyperthermic mTBI in terms of worsening histopathological and behavioral outcomes...
November 6, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29097755/lasting-deficit-in-inhibitory-control-with-mild-traumatic-brain-injury
#11
Benjamin Xu, Marco Sandrini, Sarah Levy, Rita Volochayev, Oluwole Awosika, John A Butman, Dzung L Pham, Leonardo G Cohen
Being able to focus on a complex task and inhibit unwanted actions or interfering information (i.e., inhibitory control) are essential human cognitive abilities. However, it remains unknown the extent to which mild traumatic brain injury (mTBI) may impact these critical functions. In this study, seventeen patients and age-matched healthy controls (HC) performed a variant of the Stroop task and attention-demanding 4-choice response tasks (4CRT) with identical stimuli but two contexts: one required only routine responses and the other with occasional response conflicts...
November 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29095055/diffusion-mri-findings-in-patients-with-extensive-and-minimal-post-concussion-symptoms-after-mtbi-and-healthy-controls-a-cross-sectional-study
#12
Erhard Trillingsgaard Næss-Schmidt, Jakob Udby Blicher, Anna Tietze, Charlotte Ulrikka Rask, Susanne Wulff Svendsen, Andreas Schröder, Mille Møller Thastum, Astrid Høeg Tuborgh, Oana-Veronica Frederiksen, Leif Østergaard, Simon Fristed Eskildsen, Brian Hansen, Sune Jespersen, Jørgen Feldbæk Nielsen
PRIMARY OBJECTIVES: We hypothesized that the microstructure of the corpus callosum, thalamus and hippocampus, as measured with diffusion and Mean of the Kurtosis Tensor (MKT) MRI, differs between healthy subjects and patients with extensive and minimal post-concussion symptoms (PCS) and that MKT measures correlate with PCS severity and self-reported cognitive symptoms. RESEARCH DESIGN: A cross-sectional study comparing patients with extensive PCS and patients with minimal PCS 2-5 months after mild traumatic brain injury (mTBI) with each other and with an external healthy control group...
November 2, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29084034/risk-factors-for-prolonged-symptoms-of-mild-traumatic-brain-injury-a-pediatric-sports-concussion-clinic-cohort
#13
Shayne D Fehr, Lindsay D Nelson, Kyle R Scharer, Elizabeth A Traudt, Joshua M Veenstra, Sergey S Tarima, Xue-Cheng Liu, Kevin D Walter
OBJECTIVE: To examine predictors of prolonged symptom duration from mild traumatic brain injury (mTBI) in a pediatric sports medicine specialty clinic cohort as these predictors may be distinct in this population. DESIGN: Retrospective chart review. SETTING: Outpatient specialty clinic. PATIENTS: Charts of 549 patients (age range: 10-18 years) with concussions were reviewed in an outpatient clinic that predominantly managed sports-related injuries (77...
November 13, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29069278/performance-validity-neurocognitive-disorder-and-post-concussion-symptom-reporting-in-service-members-with-a-history-of-mild-traumatic-brain-injury
#14
Sara M Lippa, Rael T Lange, Louis M French, Grant L Iverson
Objective: To examine the influence of different performance validity test (PVT) cutoffs on neuropsychological performance, post-concussion symptoms, and rates of neurocognitive disorder and postconcussional syndrome following mild traumatic brain injury (MTBI) in active duty service members. Method: Participants were 164 service members (Age: M = 28.1 years [SD = 7.3]) evaluated on average 4.1 months (SD = 5.0) following injury. Participants were divided into three mutually exclusive groups using original and alternative cutoff scores on the Test of Memory Malingering (TOMM) and the Effort Index (EI) from the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): (a) PVT-Pass, n = 85; (b) Alternative PVT-Fail, n = 53; and (c) Original PVT-Fail, n = 26...
October 21, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29060581/evidence-of-brain-functional-deficits-following-sport-related-mild-traumatic-brain-injury
#15
Tamanna Tabassum Khan Munia, Ali Haider, Reza Fazel-Rezai
Sport related mild traumatic brain injury (mTBI), generally known as a concussion, is a worldwide critical public health concern nowadays. Despite growing concern emphasized by scientific research and recent media presentation regarding mTBI and its effect in athletics life, the management, and prevention of mTBI are still not properly done. The evaluation mainly hampered due to the lack of proper knowledge, subjective nature of assessment tools including the fact that the brain functional deficits after mTBI can be mild or hidden...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28980825/does-the-fear-avoidance-model-explain-persistent-symptoms-after-traumatic-brain-injury
#16
Melloney L M Wijenberg, Sven Z Stapert, Jeanine A Verbunt, Jennie L Ponsford, Caroline M Van Heugten
BACKGROUND: A minority of patients with mild traumatic brain injury (mTBI) experience a persistent symptom complex also known as post-concussion syndrome. Explanations for this syndrome are still lacking. OBJECTIVE: To investigate if the fear avoidance model, including catastrophizing thoughts and fear avoidance behaviour, poses a possible biopsychosocial explanation for lingering symptoms and delay in recovery after traumatic brain injury (TBI) with special focus on mTBI...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28979609/examining-microstructural-white-matter-in-active-duty-soldiers-with-a-history-of-mild-traumatic-brain-injury-and-traumatic-stress
#17
Michael N Dretsch, Rael T Lange, Jeffery S Katz, Adam Goodman, Thomas A Daniel, Gopikrishna Deshpande, Thomas S Denney, Grant L Iverson, Jennifer L Robinson
BACKGROUND: There is a high comorbidity of posttraumatic stress (PTS) and mild traumatic brain injury (mTBI), with largely overlapping symptomatology, in military service members. OBJECTIVE: To examine white matter integrity associated with PTS and mTBI as assessed using diffusion tensor imaging (DTI). METHOD: Seventy-four active-duty U.S. soldiers with PTS (n = 16) and PTS with co-morbid history of mTBI (PTS/mTBI; n = 28) were compared to a military control group (n = 30)...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28972405/staying-in-the-game-a-pilot-study-examining-the-efficacy-of-protective-headgear-in-an-animal-model-of-mild-traumatic-brain-injury-mtbi
#18
Sydney Candy, Irene Ma, Jill M McMahon, Michael Farrell, Richelle Mychasiuk
PRIMARY OBJECTIVE: Rugby is one of the few contact sports that do not mandate protective headgear, possibly because studies have shown poor efficacy for protection related to concussion pathology with existing headguards. RESEARCH DESIGN: Following innovative material technology utilization to produce headgear believed to have protective capabilities, this study examined the effects of a soft-shell headgear constructed from a novel viscoelastic material, on both behaviour and serum biomarkers after high and average impact force mild traumatic brain injuries (mTBI)...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28969486/prognostic-value-of-s-100%C3%A3-protein-for-prediction-of-post-concussion-symptoms-following-a-mild-traumatic-brain-injury-systematic-review-and-meta-analysis
#19
Eric Mercier, Pier-Alexandre Tardif, Peter Cameron, Brice Lionel Batomen Kuimi, Marcel Émond, Lynne Moore, Biswadev Mitra, Jérôme Frenette, Elaine de Guise, Marie-Christine Ouellet, Martine Bordeleau, Natalie Le Sage
This systematic review and meta-analysis aimed to determine the prognostic value of S-100β protein to identify patients with post-concussion symptoms following a mild traumatic brain injury (mTBI). A search strategy was submitted to seven databases from their inception to October 2016. Individual patient data were requested. Cohort studies evaluating the association between S-100β protein level and post-concussion symptoms assessed at least seven days after the mTBI were considered. Outcomes were dichotomised as persistent (>= 3 months) or early (>= 7 days < 3 months)...
October 2, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28967326/cerebral-blood-flow-after-mild-traumatic-brain-injury-associations-between-symptoms-and-post-injury-perfusion
#20
Jaclyn A Stephens, Peiying Liu, Hanzang Lu, Stacy J Suskauer
Arterial spin labeling (ASL) has emerged as a technique for assessing mild traumatic brain injury (mTBI), as it can non-invasively evaluate cerebrovascular physiology. To date, there is substantial variability in methodology and findings of ASL studies of mTBI. While both increased and decreased perfusion are reported after mTBI, more consistency is emerging when perfusion is examined with regard to symptomology. We evaluated 15 teenage athletes 2 and 6 weeks after sports-related concussion (SRC group) using pseudo-continuous ASL...
October 1, 2017: Journal of Neurotrauma
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