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Mtbi concussion

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https://www.readbyqxmd.com/read/29726314/effect-of-depression-on-cognition-after-mild-traumatic-brain-injury-in-adults
#1
Douglas P Terry, Michelle Brassil, Grant L Iverson, William J Panenka, Noah D Silverberg
OBJECTIVE: The current study examined the effect of depression on cognitive test performance in a sample of adults seeking treatment for a mild traumatic brain injury (MTBI). We hypothesized that patients with greater depressive symptoms would perform worse on tasks of fluid cognition compared to those without depression, after controlling for potential confounds. METHOD: Patients (N = 76) completed a brief cognitive test battery (NIH Toolbox Cognition Battery; NIHTB-CB) and a depression screening questionnaire (PHQ-9) at 11...
May 4, 2018: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29712487/prospective-study-of-myelin-water-fraction-changes-after-mild-traumatic-brain-injury-in-collegiate-contact-sports
#2
Heather S Spader, Douglas C Dean, W Curt LaFrance, Neha P Raukar, G Rees Cosgrove, Stephanie A Eyerly-Webb, Anna Ellermeier, Stephen Correia, Sean C L Deoni, Jeffrey Rogg
OBJECTIVE Mild traumatic brain injury (mTBI) in athletes, including concussion, is increasingly being found to have long-term sequelae. Current imaging techniques have not been able to identify early damage caused by mTBI that is predictive of long-term symptoms or chronic traumatic encephalopathy. In this preliminary feasibility study, the authors investigated the use of an emerging magnetic resonance imaging (MRI) technique, multicomponent driven equilibrium single pulse observation of T1 and T2 (mcDESPOT), in visualizing acute and chronic white matter changes after mTBI in collegiate football and rugby players...
May 1, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29690799/prediction-of-persistent-post-concussion-symptoms-following-mild-traumatic-brain-injury
#3
Maryse C Cnossen, Joukje van der Naalt, Jacoba M Spikman, Daan Nieboer, John K Yue, Ethan A Winkler, Geoffrey Manley, Nicole von Steinbuechel, Suzanne Polinder, Ewout W Steyerberg, Hester Lingsma
Persistent post-concussion symptoms (PPCS) occur frequently after mild traumatic brain injury (mTBI). The identification of patients at risk for poor outcome remains challenging since valid prediction models are missing. The objectives of the current study were to assess the quality and clinical value of prediction models for PPCS , and to develop a new model based on the synthesis of existing models and addition of complaints at emergency department (ED). MTBI patients (Glasgow Coma Scale score 13-15) were prospectively recruited from three Dutch level I trauma centers between 2013-2015 in the UPFRONT study...
April 25, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29678928/imaging-in-pediatric-concussion-a-systematic-review
#4
REVIEW
Julia Schmidt, Kathryn S Hayward, Katlyn E Brown, Jill G Zwicker, Jennie Ponsford, Paul van Donkelaar, Shelina Babul, Lara A Boyd
CONTEXT: Pediatric mild traumatic brain injury (mTBI) is a common and poorly understood injury. Neuroimaging may index brain injury and outcome after pediatric mTBI, but remains largely unexplored. OBJECTIVE: To investigate the differences in neuroimaging findings in children/youth with mTBI. Measures of behavior, symptoms, time since injury, and age at injury were also considered. DATA SOURCES: A systematic review was conducted up to July 6, 2016...
April 20, 2018: Pediatrics
https://www.readbyqxmd.com/read/29665736/fear-avoidance-and-clinical-outcomes-from-mild-traumatic-brain-injury
#5
Noah D Silverberg, William Panenka, Grant L Iverson
Characterizing psychological factors that contribute to persistent symptoms after mild traumatic brain injury (MTBI) can inform early intervention. To determine whether fear avoidance, a known risk factor for chronic disability after musculoskeletal injury, is associated with worse clinical outcomes from MTBI, adults were recruited from four outpatient MTBI clinics and assessed at their first clinic visit (M=2.7, SD=1.5 weeks post-injury) and again 4-5 months later. Of 273 patients screened, 102 completed the initial assessment and 87 returned for the outcome assessment...
April 18, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29648487/bdnf-expression-increases-without-changes-in-play-behavior-following-concussion-in-juvenile-rats-rattus-norvegicus-brief-report
#6
Allison C F Dyck, Tammy L Ivanco
PURPOSE: Young children have a high risk of concussion or mild traumatic brain injury (mTBI). Children often appear healthy soon after mTBI, but some have pervasive cognitive and/or motor impairments. Understanding underlying mechanisms recruited after concussion may help for return to play protocols and mitigating what might be lifelong impairments. METHODS: We investigated molecular and behavioral changes in a rat model of childhood concussion. Rats received an injury or sham procedure at an age approximately equivalent to the human period of early childhood...
April 12, 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/29564659/subcortical-shape-and-neuropsychological-function-among-u-s-service-members-with-mild-traumatic-brain-injury
#7
David F Tate, Benjamin S C Wade, Carmen S Velez, Ann Marie Drennon, Jacob D Bolzenius, Douglas B Cooper, Jan E Kennedy, Matthew W Reid, Amy O Bowles, Paul M Thompson, Boris A Gutman, Jeffrey D Lewis, John L Ritter, Gerald E York, Erin D Bigler
In a recent manuscript, our group demonstrated shape differences in the thalamus, nucleus accumbens, and amygdala in a cohort of U.S. Service Members with mild traumatic brain injury (mTBI). Given the significant role these structures play in cognitive function, this study directly examined the relationship between shape metrics and neuropsychological performance. The imaging and neuropsychological data from 135 post-deployed United States Service Members from two groups (mTBI and orthopedic injured) were examined...
March 21, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29557322/is-concussion-a-risk-factor-for-epilepsy
#8
Richard Wennberg, Carmen Hiploylee, Peter Tai, Charles H Tator
BACKGROUND: Epidemiologic studies have suggested that concussion, or mild traumatic brain injury (mTBI), is associated with a twofold or greater increase in relative risk for the development of post-traumatic epilepsy. To assess the clinical validity of these findings, we analyzed the incidence of epilepsy in a large cohort of post-concussion patients in whom concussion was strictly defined according to international guidelines. METHODS: A retrospective cohort study of 330 consecutive post-concussion patients followed by a single concussion specialist...
May 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29550695/detecting-gait-abnormalities-after-concussion-or-mild-traumatic-brain-injury-a-systematic-review-of-single-task-dual-task-and-complex-gait
#9
REVIEW
Peter C Fino, Lucy Parrington, Will Pitt, Douglas N Martini, James C Chesnutt, Li-Shan Chou, Laurie A King
BACKGROUND: While a growing number of studies have investigated the effects of concussion or mild traumatic brain injury (mTBI) on gait, many studies use different experimental paradigms and outcome measures. The path for translating experimental studies for objective clinical assessments of gait is unclear. RESEARCH QUESTION: This review asked 2 questions: 1) is gait abnormal after concussion/mTBI, and 2) what gait paradigms (single-task, dual-task, complex gait) detect abnormalities after concussion...
May 2018: Gait & Posture
https://www.readbyqxmd.com/read/29545567/long-term-effects-of-mild-traumatic-brain-injuries-to-oculomotor-tracking-performances-and-reaction-times-to-simple-environmental-stimuli
#10
Alessander Danna-Dos-Santos, Sambit Mohapatra, Maria Santos, Adriana M Degani
Understanding the long-term effects of concussive events remains a challenge for the development of modern medical practices and the prevention of recurrent traumas. In this study, we utilized indices of oculomotor performance and the ability to react to simple environmental stimuli to assess the long-term motor effects of traumatic brain injury in its mildest form (mTBI). We performed analysis of eye movement accuracy, investigated the presence of abnormal eye movements, and quantified time to react to simple environmental stimuli on long-term mTBI survivors...
March 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29541337/effects-of-a-60-minute-on-ice-game-simulation-on-the-balance-error-scoring-system
#11
Philip W Cameron, Noelle C Soltero, Justin Byers
Mild traumatic brain injuries (mTBIs) are common in contact sports. There is an association between mTBIs and altered motor function. BioSway technology measures individuals' balance using the Balance Error Scoring System (BESS). Prior to incorporating BESS testing in concussion protocol, other variables that influence the BESS test require review. The objective of this study is to determine if game fatigue in hockey players also influences the BESS score. 23 male (21.08 ± 1.09) National Collegiate Athletic Association (NCAA) athletes were tested using the BioSway™ (Biodex, USA)...
2018: International Journal of Exercise Science
https://www.readbyqxmd.com/read/29517589/neuropsychological-performance-and-subjective-symptom-reporting-in-military-service-members-with-a-history-of-multiple-concussions-comparison-with-a-single-concussion-posttraumatic-stress-disorder-and-orthopedic-trauma
#12
Douglas B Cooper, Glenn Curtiss, Patrick Armistead-Jehle, Heather G Belanger, David F Tate, Matthew Reid, Amy O Bowles, Carmen S Velez, Jan E Kennedy, Rodney D Vanderploeg
OBJECTIVE: To examine differences in objective neurocognitive performance and subjective cognitive symptoms in individuals with a history of a single concussion, multiple concussions, orthopedic injuries, and posttraumatic stress disorder (PTSD). METHOD: Participants included 116 military service members who sustained a mild traumatic brain injury (mTBI) during combat deployment. Subjects were subdivided into groups based on concussion frequency: a single concussion (n = 42), 2 concussions (n = 21), and 3 or more concussions (n = 53)...
March 2018: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/29515515/chronic-hypopituitarism-associated-with-increased-postconcussive-symptoms-is-prevalent-after-blast-induced-mild-traumatic-brain-injury
#13
Arundhati Undurti, Elizabeth A Colasurdo, Carl L Sikkema, Jaclyn S Schultz, Elaine R Peskind, Kathleen F Pagulayan, Charles W Wilkinson
The most frequent injury sustained by US service members deployed to Iraq or Afghanistan is mild traumatic brain injuries (mTBI), or concussion, by far most often caused by blast waves from improvised explosive devices or other explosive ordnance. TBI from all causes gives rise to chronic neuroendocrine disorders with an estimated prevalence of 25-50%. The current study expands upon our earlier finding that chronic pituitary gland dysfunction occurs with a similarly high frequency after blast-related concussions...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29498077/persistent-symptoms-and-activity-changes-three-months-after-mild-traumatic-brain-injury
#14
Rebecca Cooksley, Emma Maguire, Natasha A Lannin, Carolyn A Unsworth, Michelle Farquhar, Claire Galea, Biswadev Mitra, Julia Schmidt
BACKGROUND/AIM: Approximately, 80% of traumatic brain injuries are considered mild in severity. Mild traumatic brain injury (mTBI) may cause temporary or persisting impairments that can adversely affect an individual's ability to participate in daily occupations and life roles. This study aimed to identify symptoms, factors predicting level of symptoms and functional and psycho-social outcomes for participants with mTBI three months following injury. METHOD: Patients discharged from the Emergency Department of a major metropolitan hospital with a diagnosis of mTBI were contacted by telephone three months after injury...
March 2, 2018: Australian Occupational Therapy Journal
https://www.readbyqxmd.com/read/29446658/post-concussive-symptoms-after-a-mild-traumatic-brain-injury-during-childhood-and-adolescence
#15
Nicola J Starkey, Kelly Jones, Rosalind Case, Alice Theadom, Suzanne Barker-Collo, Valery Feigin
OBJECTIVE: Mild traumatic brain injury (mTBI) is common injury during childhood and adolescence but the long-term outcomes are poorly understood. This study examined post-concussive symptoms and behavioural outcomes in children and adolescents up to 24 months post-mTBI. METHOD: Parents of children aged 8-15 years with mTBI completed the BASC-2 and Rivermead Post-Concussion Symptoms Questionnaire at baseline, 1-, 6-, 12- and 24 months post-injury. An age-matched traumatic brain injury-free cohort was recruited and assessed at 12- and 24 months...
2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29391082/common-data-elements-for-concussion-in-tertiary-care-phase-one-in-ontario
#16
Cindy Hunt, Alicja Michalak, Donna Ouchterlony, Shawn Marshall, Cheryl Masanic, Chantal Vaidyanath, Shree Bhalerao, Michael D Cusimano, Deanna Quon, Lisa K Fischer, Andrew Baker
BACKGROUND: Standardized data collection for traumatic brain injury (TBI) (including concussion) using common data elements (CDEs) has strengthened clinical care and research capacity in the United States and Europe. Currently, Ontario healthcare providers do not collect uniform data on adult patients diagnosed with concussion. OBJECTIVE: The Ontario Concussion Care Strategy (OCCS) is a collaborative network of multidisciplinary healthcare providers, brain injury advocacy groups, patient representatives, and researchers with a shared vision to improve concussion care across the province, starting with the collection of standardized data...
November 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29388838/untangling-chronic-pain-and-post-concussion-symptoms-the-significance-of-depression
#17
Deborah L Snell, Rachelle Martin, A D Macleod, Lois J Surgenor, Richard J Siegert, E Jean C Hay-Smith, Tracy Melzer, Gary J Hooper, Tim Anderson
OBJECTIVES: Post-concussion-like symptoms (PCS) are common in patients without a history of brain injury, such as those with chronic pain (CP). This exploratory study examined neuro-cognitive and psychological functioning in patients with PCS following mild traumatic brain injury (mTBI) or CP, to assess unique and overlapping phenomenology. METHODS: In this case-control study, participants (n = 102) with chronic symptoms after mTBI (n = 45) were matched with mTBI recovered (n = 31) and CP groups (n = 26), on age, gender, ethnicity and education...
2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29376093/lifelong-behavioral-and-neuropathological-consequences-of-repetitive-mild-traumatic-brain-injury
#18
Benoit C Mouzon, Corbin Bachmeier, Joseph O Ojo, Christopher M Acker, Scott Ferguson, Daniel Paris, Ghania Ait-Ghezala, Gogce Crynen, Peter Davies, Michael Mullan, William Stewart, Fiona Crawford
Objective: Exposure to repetitive concussion, or mild traumatic brain injury (mTBI), has been linked with increased risk of long-term neurodegenerative changes, specifically chronic traumatic encephalopathy (CTE). To date, preclinical studies largely have focused on the immediate aftermath of mTBI, with no literature on the lifelong consequences of mTBI in these models. This study provides the first account of lifelong neurobehavioral and histological consequences of repetitive mTBI providing unique insight into the constellation of evolving and ongoing pathologies with late survival...
January 2018: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29373947/reduced-functional-connectivity-in-adults-with-persistent-post-concussion-symptoms-a-functional-near-infrared-spectroscopy-study
#19
Lia M Hocke, Chris C Duszynski, Chantel T Debert, Diane Dleikan, Jeff F Dunn
Concussion, or mild traumatic brain injury (mTBI), accounts for ∼80% of all TBIs across North America. The majority of mTBI patients recover within days to weeks; however, 14-36% of the time, acute mTBI symptoms persist for months or even years and develop into persistent post-concussion symptoms (PPCS). There is a need to find biomarkers in patients with PPCS, to improve prognostic ability and to provide insight into the pathophysiology underlying chronic symptoms. Recent research has pointed toward impaired network integrity and cortical communication as a biomarker...
March 23, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29368186/protection-before-impact-the-potential-neuroprotective-role-of-nutritional-supplementation-in-sports-related-head-trauma
#20
REVIEW
Jonathan M Oliver, Anthony J Anzalone, Stephanie M Turner
Even in the presence of underreporting, sports-related concussions/mild traumatic brain injuries (mTBI) are on the rise. In the absence of proper diagnosis, an athlete may return to play prior to full recovery, increasing the risk of second-impact syndrome or protracted symptoms. Recent evidence has demonstrated that sub-concussive impacts, those sustained routinely in practice and competition, result in a quantifiable pathophysiological response and the accumulation of both concussive and sub-concussive impacts sustained over a lifetime of sports participation may lead to long-term neurological impairments and an increased risk of developing neurodegenerative diseases...
January 24, 2018: Sports Medicine
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