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Pain killers dose and images

Go Ito, Kousuke Kanemoto
In Japan, indications for opioid analgesics, once exclusively used as pain killers for patients suffering from malignant cancer, have been expanded for a wide range of pain. Herein we report a patient with opioid-induced delirium associated with the administration of buprenorphine patches that was well below the indicated therapeutic range limit. An 82-year-old woman was referred to us from an orthopaedic practitioner for uncontrollable behavioural problems apparently caused by the beginning of dementia; the patient had gradually developed disorientation, visual hallucinations, and delusions...
June 2013: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
Kyoung-Tae Kim, Young-Baeg Kim, Hee Jun Kim, Young Joo Cha, Sang Jae Lee, Eunkyung Park
STUDY DESIGN: This case report shows primary natural killer (NK)/T-cell lymphoma originating in the spine as the first case of successful treatment with autologous stem cell transplantation, along with case presentation and literature review. OBJECTIVE: For the proper treatment of this spinal tumor, the pathologic confirmation includes immunophenotypic profiling, the understanding of tumor characteristics, and the consideration of spinal stability are necessary...
May 1, 2012: Spine
Hiroyuki Kubo, Thomas A Gardner, Yoshitaka Wada, Kenneth S Koeneman, Akinobu Gotoh, Ling Yang, Chinghai Kao, So Dug Lim, Mahul B Amin, Hua Yang, Margaret E Black, Shigeji Matsubara, Masayuki Nakagawa, Jay Y Gillenwater, Haiyen E Zhau, Leland W K Chung
Osteocalcin (OC), a major noncollagenous bone matrix protein, is expressed prevalently in prostate cancer epithelial cells, adjacent fibromuscular stromal cells, and osteoblasts in locally recurrent prostate cancer and prostate cancer bone metastasis [Matsubara, S., Wada, Y., Gardner, T.A., Egawa, M., Park, M.S., Hsieh, C.L., Zhau, H.E., Kao, C., Kamidono, S., Gillenwater, J.Y., and Chung, L.W. (2001). Cancer Res. 61, 6012-6019]. We constructed an adenovirus vector carrying osteocalcin promoter-driven herpes simplex virus thymidine kinase (Ad-OC-hsv-TK) to cotarget prostate cancer cells and their surrounding stromal cells...
February 10, 2003: Human Gene Therapy
O Andersen, J Lycke, P O Tollesson, A Svenningsson, B Runmarker, A S Linde, M Aström, P Gjörstrup, S Ekholm
The synthetic immunomodulator Linomide, a quinoline-3-carboxamide, has a profound inhibitory influence in several experimental autoimmune diseases, including acute and chronic experimental allergic encephalomyelitis. In a double-blind trial, 31 patients with relapsing-remitting multiple sclerosis were randomized to oral doses of 2.5 mg Linomide or placebo once a day for six months. Fourteen patients receiving Linomide and 14 receiving placebo completed the trial, and the results were based on this population...
October 1996: Neurology
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