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Bio-Kult

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https://www.readbyqxmd.com/read/29801486/a-randomized-placebo-controlled-clinical-trial-of-a-multi-strain-probiotic-formulation-bio-kult%C3%A2-in-the-management-of-diarrhea-predominant-irritable-bowel-syndrome
#1
Shamsuddin M Ishaque, S M Khosruzzaman, Dewan Saifuddin Ahmed, Mukesh Prasad Sah
BACKGROUND: Accumulating evidence supports the view that an imbalance of gut bacteria contributes to IBS, and that increasing the mass of beneficial species may reduce the numbers of pathogenic bacteria and help alleviate symptoms. METHODS: In this double-blind trial 400 adult patients with moderate-to-severe symptomatic diarrhea-predominant IBS (IBS-D) were randomized to treatment with the multi-strain probiotic Bio-Kult® (14 different bacterial strains) or placebo for 16 weeks...
May 25, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/23392622/comparative-in-vitro-inhibition-of-urinary-tract-pathogens-by-single-and-multi-strain-probiotics
#2
COMPARATIVE STUDY
C M C Chapman, G R Gibson, S Todd, I Rowland
PURPOSE: Multi-species probiotic preparations have been suggested as having a wide spectrum of application, although few studies have compared their efficacy with that of individual component strains at equal concentrations. We therefore tested the ability of 4 single probiotics and 4 probiotic mixtures to inhibit the urinary tract pathogens Escherichia coli NCTC 9001 and Enterococcus faecalis NCTC 00775. METHODS: We used an agar spot test to test the ability of viable cells to inhibit pathogens, while a broth inhibition assay was used to assess inhibition by cell-free probiotic supernatants in both pH-neutralised and non-neutralised forms...
September 2013: European Journal of Nutrition
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