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Vitamin E

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https://www.readbyqxmd.com/read/28340263/myrciaria-dubia-an-amazonian-fruit-population-structure-and-its-implications-for-germplasm-conservation-and-genetic-improvement
#1
C F Nunes, T A Setotaw, M Pasqual, E A Chagas, E G Santos, D N Santos, C G B Lima, G M A Cançado
Myrciaria dubia (camu-camu) is an Amazon tree that produces a tart fruit with high vitamin C content. It is probably the fruit with the highest vitamin C content among all Brazilian fruit crops and it can be used to supplement daily vitamin C dose. This property has attracted the attention of consumers and, consequently, encouraged fruit farmers to produce it. In order to identify and select potential accessions for commercial exploitation and breeding programs, M. dubia has received considerable research attention...
March 22, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28340119/the-risk-of-nephrolithiasis-is-causally-related-to-inactive-matrix-gla-protein-a-marker-of-vitamin-k-status-a-mendelian-randomization-study-in-a-flemish-population
#2
Fang-Fei Wei, Lutgarde Thijs, Zhen-Yu Zhang, Lotte Jacobs, Wen-Yi Yang, Erika Salvi, Lorena Citterio, Nicholas Cauwenberghs, Tatiana Kuznetsova, Nadja E A Drummen, Azusa Hara, Paolo Manunta, Yan Li, Peter Verhamme, Karel Allegaert, Daniele Cusi, Cees Vermeer, Jan A Staessen
Background.: Vitamin K (VK)-dependent γ-glutamate carboxylation and serine phosphorylation activate matrix Gla protein (MGP) to a potent locally acting inhibitor of calcification. Nephrolithiasis represents a process of unwanted calcification associated with substantial mortality and high recurrence rates. We hypothesized that the risk of nephrolithiasis increases with VK shortage, as exemplified by higher plasma levels of desphospho-uncarboxylated MGP (dp-ucMGP). Methods...
March 15, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28339160/biofortification-of-riboflavin-and-folate-in-idli-batter-based-on-fermented-cereal-and-pulse-by-lactococcus-lactis-n8-and-saccharomyces-boulardii-saa655-in-idli-batter
#3
Suresh Chander C R, Bhawani Chamlagain, Susanna Kariluoto, Vieno Piironen, Per E J Saris
AIMS: Lactococcus lactis N8 and Saccharomyces boulardii SAA655 were investigated for their ability to synthesize B- vitamins (riboflavin and folate) and their functional role as microbial starters in idli fermentation. METHODS AND RESULTS: In this study, ultra-high performance liquid chromatography (UHPLC) and microbiological assay were used to determine the total riboflavin and folate content, respectively. Increased levels of folate were evident in both L. lactis N8 and S...
March 24, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28337028/modifiable-risk-factors-of-maternal-postpartum-weight-retention-an-analysis-of-their-combined-impact-and-potential-opportunities-for-prevention
#4
J L Hollis, S R Crozier, H M Inskip, C Cooper, K M Godfrey, N C Harvey, C E Collins, S M Robinson
BACKGROUND/OBJECTIVES: Pregnancy triggers a physiological change in weight status. Postpartum weight retention in the childbearing years can substantially alter a woman's weight gain trajectory, with several potential contributing factors identified. Most research has relied on women's recall of pre-pregnancy weight during pregnancy or later, and not considered risk factors in combination. Using measured pre-pregnancy weight, this study aimed to examine the associations of maternal postpartum weight retention with parity, pre-pregnancy BMI, excessive gestational weight gain (GWG), maternal serum vitamin D concentration and dietary Glycaemic Index in early and late pregnancy and breastfeeding duration, including analysis of the combined impact of potentially modifiable risk factors...
March 24, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28336109/multivitamin-mineral-supplements-rationale-and-safety
#5
REVIEW
Hans K Biesalski, Jana Tinz
Multivitamin/mineral supplements (MVMs) are widely used in many populations. MVMs, together with iron and folic acid, are recommended for pregnant women to improve birth outcome and to reduce low-birthweight and rates of miscarriage. However, MVM use is common in the general population as well. The aim of the present review was to evaluate the safety of long-term use of these supplements. To examine the safety of MVM use, we performed a literature search for randomized controlled studies involving supplementation with a combination of at least nine vitamins and three minerals at a maximum concentration of 100% of the Recommended Dietary Allowance...
April 2017: Nutrition
https://www.readbyqxmd.com/read/28335738/genome-wide-expression-profiling-establishes-novel-modulatory-roles-of-vitamin-c-in-thp-1-human-monocytic-cell-line
#6
Sakshi Dhingra Batra, Malobi Nandi, Kriti Sikri, Jaya Sivaswami Tyagi
BACKGROUND: Vitamin C (vit C) is an essential dietary nutrient, which is a potent antioxidant, a free radical scavenger and functions as a cofactor in many enzymatic reactions. Vit C is also considered to enhance the immune effector function of macrophages, which are regarded to be the first line of defence in response to any pathogen. The THP-1 cell line is widely used for studying macrophage functions and for analyzing host cell-pathogen interactions. RESULTS: We performed a genome-wide temporal gene expression and functional enrichment analysis of THP-1 cells treated with 100 μM of vit C, a physiologically relevant concentration of the vitamin...
March 23, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28335649/plasma-growth-arrest-specific-6-levels-in-term-and-preterm-newborns
#7
E Eksi Alp, N Altinkaya, Z Cagman, F Uras
OBJECTIVE: Growth Arrest-Specific 6 (GAS6) is a vitamin K-dependent protein. Despite a similar structure to Protein S, it has no anticoagulant activity. An association between GAS6 and some diseases for adults has been reported. In the absence of prospective clinical studies of GAS6 in neonates, so far, the objective of this study is to obtain, for the first time, plasma GAS6 levels before and after vitamin K1 prophylaxis in full-term and pre-term newborns. METHODS: 80 newborn (40 term and 40 preterm) were recruited for this study...
March 23, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28335637/reversing-the-anticoagulation-effects-of-dabigatran
#8
William E Dager, Linda Banares
The standard of care for oral anticoagulation therapy has primarily been warfarin, which is limited by its indirect mechanism-of-action, variable kinetics, tolerability, and routine monitoring concerns. The direct-acting oral anticoagulants (DOACs) have predictable pharmacokinetics and pharmacodynamics, and improved safety and efficacy compared to warfarin for the prevention of stroke in patients with nonvalvular atrial fibrillation and prevention or management of venous thromboembolism. Consequential bleeding is a concern with all anticoagulants...
March 24, 2017: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/28335483/land-use-for-edible-protein-of-animal-origin-a-review
#9
REVIEW
Gerhard Flachowsky, Ulrich Meyer, Karl-Heinz Südekum
The present period is characterized by a growing world population and a higher demand for more and better quality food, as well as other products for an improved standard of living. In the future, there will be increasingly strong competition for arable land and non-renewable resources such as fossil carbon-sources, water, and some minerals, as well as between food, feed, fuel, fiber, flowers, and fun (6 F's). Proteins of animal origin like milk, meat, fish, eggs and, probably, insects are very valuable sources of essential amino acids, minerals and vitamins, but their production consumes some non-renewable resources including arable land and causes considerable emissions...
March 18, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28335380/vitamin-e-nicotinate
#10
REVIEW
Kimbell R Duncan, Yuichiro J Suzuki
Vitamin E refers to a family of compounds that function as lipid-soluble antioxidants capable of preventing lipid peroxidation. Naturally occurring forms of vitamin E include tocopherols and tocotrienols. Vitamin E in dietary supplements and fortified foods is often an esterified form of α-tocopherol, the most common esters being acetate and succinate. The vitamin E esters are hydrolyzed and converted into free α-tocopherol prior to absorption in the intestinal tract. Because its functions are relevant to many chronic diseases, vitamin E has been extensively studied in respect to a variety of diseases as well as cosmetic applications...
March 13, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28335085/modifications-in-dietary-and-alcohol-intakes-between-before-and-after-cancer-diagnosis-results-from-the-prospective-population-based-nutrinet-sant%C3%A3-cohort
#11
Philippine Fassier, Laurent Zelek, Lucie Lécuyer, Patrick Bachmann, Marina Touillaud, Nathalie Druesne-Pecollo, Pilar Galan, Patrice Cohen, Hélène Hoarau, Paule Latino-Martel, Emmanuelle Kesse-Guyot, Julia Baudry, Serge Hercberg, Mélanie Deschasaux, Mathilde Touvier
Post-diagnosis diet and alcohol consumption may be associated with cancer prognosis, recurrence and mortality. Our aim was to investigate food, nutrient and alcohol intake variations between before and after cancer diagnosis and their determinants in a prospective cohort. Subjects (n=696) were incident cancer cases diagnosed in the NutriNet-Santé cohort between 2009 and 2016. Food, nutrient and alcohol intakes were prospectively collected using repeated non-consecutive 24-h dietary records since subjects' inclusion (i...
March 23, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28334709/micronutrients-essential-fatty-acids-and-bone-health-in-phenylketonuria
#12
Serwet Demirdas, Francjan J van Spronsen, Carla E M Hollak, J Hanneke van der Lee, Peter H Bisschop, Fred M Vaz, Nienke M Ter Horst, M Estela Rubio-Gozalbo, Annet M Bosch
INTRODUCTION: In phenylketonuria (PKU), a natural protein-restricted dietary treatment prevents severe cognitive impairment. Nutrient deficiencies may occur due to strict diet. This study is aimed at evaluating the dietary intake and blood concentrations of micronutrients and essential fatty acids (FA), bone mineral density (BMD) and fracture history in patients on long-term dietary treatment. METHODS: Sixty early diagnosed Dutch patients (aged 1-39 years) were included in a multi-center cross-sectional study...
March 24, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28333357/dietary-patterns-foods-and-nutrients-in-male-fertility-parameters-and-fecundability-a-systematic-review-of-observational-studies
#13
Albert Salas-Huetos, Mònica Bulló, Jordi Salas-Salvadó
BACKGROUND: Infertility is a global public health issue, affecting 15% of all couples of reproductive age. Male factors, including decreased semen quality, are responsible for ~25% of these cases. The dietary pattern, the components of the diet and nutrients have been studied as possible determinants of sperm function and/or fertility. OBJECTIVE AND RATIONALE: Previous systematic reviews have been made of the few heterogeneous low-quality randomized clinical trials (RCTs) conducted in small samples of participants and investigating the effect of specific nutrients and nutritional supplements on male infertility...
March 10, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28331457/visual-loss-retinal-hemorrhages-and-optic-disc-edema-resulting-from-thiamine-deficiency-following-bariatric-surgery-complicated-by-prolonged-vomiting
#14
Andrew W Lawton, Nicholas E Frisard
BACKGROUND: Vision loss resulting from thiamine deficiency is a recognized complication of bariatric surgery. Most patients with such vision loss have Wernicke encephalopathy with characteristic changes seen on neuroimaging. Other patients may have retinal hemorrhages, optic disc edema, and peripheral neuropathy without Wernicke encephalopathy. The risk for thiamine deficiency is potentiated by the presence of prolonged vomiting. CASE REPORT: A 37-year-old female presented with abrupt onset of vision loss and peripheral neuropathy following bariatric surgery...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/28331417/%C3%AE-tocotrienol-inhibits-tgf-%C3%AE-1-induced-contractile-phenotype-expression-of-human-airway-smooth-muscle-cells
#15
Takehito Fukushima, Akira Yamasaki, Tomoya Harada, Hiroki Chikumi, Masanari Watanabe, Ryota Okazaki, Miki Takata, Yasuyuki Hasegawa, Jun Kurai, Masaaki Yanai, Akihiro Yamamoto, Yuriko Sueda, Andrew J Halayko, Eiji Shimizu
BACKGROUND: Tocotrienols, members of the vitamin E family, exist in four different isoforms (α, β, γ and δ tocotrienol) that have can be protective against brain damage, as well as having anticancer effects in vivo and in vitro. We have shown that γ-tocotrienol inhibits human airway smooth muscle cell proliferation and migration induced by platelet-derived growth factor (PDGF)-BB by suppressing RhoA activation. In this study, we tested whether γ-tocotrienol modulates transforming growth factor (TGF) -β-induced induction of human airway smooth muscle (ASM) into a contractile phenotype and concomitant synthesis of extracellular matrix proteins...
March 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28330850/neither-vitamin-e-nor-selenium-prevents-dementia-researchers-find
#16
Jacqui Wise
No abstract text is available yet for this article.
March 21, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28330787/acute-impact-of-caffeinated-alcoholic-beverages-on-cognition-a-systematic-review
#17
REVIEW
Laurence Lalanne, Pierre-Eric Lutz, François Paille
INTRODUCTION: Energy drinks are popular beverages that are supposed to counteract sleepiness, increase energy, maintain alertness and reduce symptoms of hangover. Cognitive enhancing seems to be related to many compounds such as caffeine, taurine and vitamins. Currently, users mostly combine psychostimulant effects of energy drinks to counteract sedative effects of alcohol. However, recent literature suggests that this combination conducts to feel less intoxicated but still impaired. The goal of the present article is to review cognitive impact and subjective awareness in case of caffeinated alcoholic beverage (CAB) intoxication...
March 19, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28329672/vitamin-d-and-skin-aging
#18
Merel A Hamer, Raymond Noordam, Luba M Pardo, Diana Van Heemst, David A Gunn, Tamar Nijsten
BackgroundThe relationship between 25-hydroxyvitamin D and different phenotypes of skin aging (e.g., wrinkles, pigmented spots, telangiectasia, perceived age) is unclear. We investigated the association between vitamin D levels and skin aging phenotypes in middle-aged participants from the Rotterdam Study (RS) and Leiden Longevity Study (LLS).MethodsStandardized facial photographs were taken of North-European participants from the RS (N=3,831; 58.2% female, median age 66.5) and the LLS (N=661; 50.5% female, median age 63...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329641/differences-in-incidence-and-persistence-of-atopic-dermatitis-by-race-ethnicity
#19
M Blomberg, S L Rifas-Shiman, Ca Jr Camargo, D R Gold, J P Thyssen, A A Litonjua, M W Gillman, M M Asgari, E Oken
BackgroundMost studies on racial disparities in childhood atopic dermatitis (AD) did not consider persistent AD or account for differences in vitamin D status.MethodsAmong 1418 children recruited from a Massachusetts HMO into the pre-birth Project Viva cohort, we examined associations of child's race/ethnicity with maternal report of child's AD diagnosis by annual questionnaires. We used multivariable logistic regression adjusted for socio- demographics (maternal education, household income, smoking exposure, parental atopy, breastfeeding duration, child sex) and cord blood 25-hydroxyvitamin D, to estimate odds ratios (OR) of incident AD by early childhood (median age 3...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329534/acquired-aquagenic-papulotranslucent-acrokeratoderma
#20
Sarah E Yagerman, Marie Lager, Nicholas A Soter
Aquagenic papulotranslucent acrokeratoderma isa rare condition with the development of white-totransluscentpapules and plaques after exposureto water. While the first report was described asan autosomal dominant hereditary condition,there have since been acquired cases reported inassociation with cystic fibrosis, with prior exposureto a drug, or as an idiopathic condition. We presenta 24-year-old man with acquired aquagenicpapulotranslucent acrokeratoderma that has beenpresent since infancy, without a family history,without prior drug exposure, and without anypersonal or family history of cystic fibrosis...
December 15, 2016: Dermatology Online Journal
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