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https://www.readbyqxmd.com/read/29037399/comparison-of-heat-strain-recovery-in-different-anti-heat-stress-clothing-ensembles-after-work-to-exhaustion
#1
Yijie Zhao, Wen Yi, Albert P C Chan, Daniel W M Chan
A hot environment combined with physically demanding tasks can subject workers to a higher risk of heat stress. A series of regulations and guidelines have been proposed to design appropriate anti-heat stress work uniform to reduce body heat strain. The present study aimed to examine heat strain recovery in different anti-heat stress clothing ensembles after work to exhaustion in the heat. 10 healthy males performed intermittent treadmill running/walking to exhaustion, followed by 30min passive recovery sitting in a climatic chamber, which simulated the hot and humid outdoor environment (34°C temperature, 60% relative humidity, 0...
October 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29023952/pharmacokinetics-and-electrophysiological-effects-of-sotalol-hydrochloride-in-horses
#2
B Broux, D De Clercq, A Decloedt, L Vera, M Devreese, R Gehring, S Croubels, G van Loon
BACKGROUND: Arrhythmias in horses may require long term anti-arrhythmic therapy. Unfortunately, oral anti-arrhythmic drugs for use in horses are currently scarce. In human patients and small animals, sotalol, a β-blocker with class III anti-arrhythmic properties, is often used for long-term treatment. OBJECTIVES: To determine the pharmacokinetics of sotalol at multiple oral dosages in unfasted horses, as well as the effects on electro- and echocardiographic measurements, right atrial and ventricular monophasic action potential (MAP) and effective refractory period (ERP)...
October 10, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29023279/syncope-episodes-and-blood-flow-restriction-training
#3
Juan Martín-Hernández, Alejandro Santos-Lozano, Carl Foster, Alejandro Lucia
The combination of low-load resistance training [or more recently, neuromuscular electrical stimulation (NMES)] with a moderate local blood flow restriction (BFR) is becoming a widespread training and rehabilitation method. Scientific data indicate the overall safety of BFR, at least in healthy young people. However, it has been associated with side effects, usually minor, and further research is warranted regarding the safety and efficacy of this technique, especially in clinical populations. We found 3 syncope/presyncopal episodes among 21 healthy people (9 men), all occurring in men and during familiarization sessions (in which BFR was applied alone) but not thereafter (BFR sessions combined with NMES): 1 subject experienced a brief syncope and 2 other subjects exhibited presyncopal symptoms (sweating, lightheadedness, and pallor)...
October 6, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29021192/orderly-recruitment-of-thermoeffectors-in-resting-humans
#4
Zachary J Schlader, James R Sackett, Suman Sarker, Blair D Johnson
The recruitment of thermoeffectors, including thermoregulatory behavior, relative to changes in body temperature has not been quantified in humans. We tested the hypothesis that changes in skin blood flow, behavior, and sweating or metabolic rate are initiated with increasing changes in mean skin temperature (Tskin) in resting humans. While wearing a water perfused suit, twelve healthy young adults underwent heat (HEAT) and cold (COLD) stress that induced gradual changes in Tskin Subjects controlled the temperature of their dorsal neck to their perceived thermal comfort...
October 11, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28989117/brachial-artery-blood-flow-dynamics-during-sinusoidal-leg-cycling-exercise-in-humans
#5
Yoshiyuki Fukuba, Masako Y Endo, Ayaka Kondo, Yuka Kikugawa, Kohei Miura, Hideaki Kashima, Masaki Fujimoto, Naoyuki Hayashi, Yoshiyuki Fukuoka, Shunsaku Koga
To explore the control of the peripheral circulation of a nonworking upper limb during leg cycling exercise, blood flow (BF) dynamics in the brachial artery (BA) were determined using a sinusoidal work rate (WR) exercise. Ten healthy subjects performed upright leg cycling exercise at a constant WR for 30 min, followed by 16 min of sinusoidal WR consisting of 4-min periods of WR fluctuating between a minimum output of 20 W and a maximum output corresponding to ventilatory threshold (VT). Throughout the protocol, pulmonary gas exchange, heart rate (HR), mean arterial blood pressure (MAP), blood velocity (BV), and cross-sectional area of the BA, forearm skin BF (SBF), and sweating rate (SR) were measured...
October 2017: Physiological Reports
https://www.readbyqxmd.com/read/28942325/effects-of-stimulation-technique-anatomical-region-and-time-on-human-sweat-lipid-mediator-profiles
#6
Karan Agrawal, Justin D Waller, Theresa L Pedersen, John W Newman
Few studies compare sampling protocol effect on sweat composition. Here we evaluate the impact of sweat stimulation mode and site of collection on lipid mediator composition. Sweat from healthy males (n=7) was collected weekly for three weeks from the volar forearm following either pilocarpine iontophoresis or exercise, and from the forearm, back and thigh following pilocarpine iontophoresis only. Sweat content of over 150 lipid mediators were measured by liquid chromatography-tandem mass spectrometry. Seventy lipid mediators were routinely detected, including prostanoids, alcohols, diols, epoxides, ketones, nitrolipids, N-acylethanolamides, monoacylglycerols, and ceramides...
September 21, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28942302/congenital-cutaneous-panadnexal-papillomatous-hamartomas-in-a-calf
#7
I B Veiga, M Welle, J S Agerholm
Several cauliflower-like alopecic masses arose on the head of an otherwise healthy, full-term newborn Jersey × Belgian blue heifer, which was humanely destroyed shortly after birth due to the severity of the skin lesions. Microscopically, the masses were composed of multiple papillary projections displaying well-differentiated sebaceous glands surrounded by a moderate number of well-developed sweat glands, as well as embryonic and fully developed, but dysplastic hair follicles. Thick branching connective tissue stalks supported these adnexal components...
August 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28940663/a-novel-method-to-assess-the-potential-role-of-sweating-abnormalities-in-the-pathogenesis-of-ad
#8
Yurie Shimoda-Komatsu, Yohei Sato, Yoshimi Yamazaki, Ryo Takahashi, Tetsuo Shiohara
BACKGROUND: Although atopic dry skin is believed to be caused by defects in skin genes important for maintaining skin barrier function, the role of sweat in atopic dermatitis (AD) has been apparently underestimated. Given the great capacity of sweat to maintain and increase skin hydration, defective sweating responses may be a logical place to look for changes that predispose individuals to the disease. METHODS: We investigated how disease process and sweating defects progress from early asymptomatic stages to the onset of clinically apparent disease by employing the impression mold technique, which allows an accurate quantification of individual sweat gland/duct activity in relation to skin surface topography...
September 23, 2017: Experimental Dermatology
https://www.readbyqxmd.com/read/28936997/influence-of-age-and-gender-on-the-function-of-postganglionic-sympathetic-sudomotor-axons
#9
Kedar Mal, Hulegar A Abhishekh, Mahavir Prasad Chawla, Trichur R Raju, Talakad N Sathyaprabha
BACKGROUND: The quantitative sudomotor axon reflex test (QSART) is an autonomic function test to evaluate the function of postganglionic sympathetic sudomotor axons. The QSART is used for research and in clinical assessment of various neurological diseases, but few studies have assessed the influence of age, gender and reported a normative range. We assessed the influence of age and gender on QSART parameters. METHODS: We recruited 61 healthy volunteers (41 men and 20 women) after obtaining written informed consent...
May 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28924220/towards-addressing-the-body-electrolyte-environment-via-sweat-analysis-pilocarpine-iontophoresis-supports-assessment-of-plasma-potassium-concentration
#10
Donato Vairo, Laurie Bruzzese, Marion Marlinge, Lea Fuster, Nabil Adjriou, Nathalie Kipson, Philippe Brunet, Jennifer Cautela, Yves Jammes, Giovanna Mottola, Stephane Burtey, Jean Ruf, Regis Guieu, Emmanuel Fenouillet
Electrolyte concentration in sweat depends on environmental context and physical condition but also on the pathophysiological status. Sweat analyzers may be therefore the future way for biological survey although how sweat electrolyte composition can reflect plasma composition remains unclear. We recruited 10 healthy subjects and 6 patients to have a broad range of plasma electrolyte concentrations (chloride, potassium and sodium) and pH. These variables were compared to those found in sweat produced following cycling exercise or pilocarpine iontophoresis, a condition compatible with operating a wearable device...
September 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28899687/proteomic-profiling-of-sweat-exosome-suggests-its-involvement-in-skin-immunity
#11
Chang-Xian Wu, Zheng-Fei Liu
The healthy human skin sustains an effective immune defense mechanism, formed by a complex physical and chemical epidermal barrier that coordinates with different cellular components of the skin immune system. However, the mechanism how skin cells regulate local immune homeostasis in health and disease contexts is not well known. To investigate whether exosomes exist in sweat, sweat samples from healthy individuals were collected after aerobic exercise. Sweat exosome was isolated via differential ultracentrifugation, observed under transmission electron microscope, measured by dynamic light scattering and confirmed by immunoblot...
September 9, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28894421/impact-of-different-personal-protective-clothing-on-wildland-firefighters-physiological-strain
#12
Belén Carballo-Leyenda, José G Villa, Jorge López-Satué, Jose A Rodríguez-Marroyo
Wildfire firefighting is an extremely demanding occupation performed under hot environment. The use of personal protective clothing (PPC) is needed to protect subjects from the thermal exposure. However, the additional use of PPC may increase the wildland firefighters' physiological strain, and consequently limit their performance. The aim of this study was to analyze the effect of four different PPC on the physiological strain of wildland firefighters under moderate conditions (30°C and 30% RH). Eight active and healthy wildland firefighters performed a submaximal walking test wearing a traditional short sports gear and 4 different PPC...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28853743/evaluation-and-review-of-body-fluids-saliva-sweat-and-tear-compared-to-biochemical-hydration-assessment-markers-within-blood-and-urine
#13
REVIEW
M Villiger, R Stoop, T Vetsch, E Hohenauer, M Pini, P Clarys, F Pereira, R Clijsen
Evaluating and testing hydration status is increasingly requested by rehabilitation, sport, military and performance-related activities. Besides commonly used biochemical hydration assessment markers within blood and urine, which have their advantages and limitations in collection and evaluating hydration status, there are other potential markers present within saliva, sweat or tear. This literature review focuses on body fluids saliva, sweat and tear compared to blood and urine regarding practicality and hydration status influenced by fluid restriction and/or physical activity...
August 30, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28813999/upper-limb-prosthetic-control-using-wearable-multichannel-mechanomyography
#14
Samuel Wilson, Ravi Vaidyanathan
In this paper we introduce a robust multi-channel wearable sensor system for capturing user intent to control robotic hands. The interface is based on a fusion of inertial measurement and mechanomyography (MMG), which measures the vibrations of muscle fibres during motion. MMG is immune to issues such as sweat, skin impedance, and the need for a reference signal that is common to electromyography (EMG). The main contributions of this work are: 1) the hardware design of a fused inertial and MMG measurement system that can be worn on the arm, 2) a unified algorithm for detection, segmentation, and classification of muscle movement corresponding to hand gestures, and 3) experiments demonstrating the real-time control of a commercial prosthetic hand (Bebionic Version 2)...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28809624/spinal-orthoses-the-crucial-role-of-comfort-on-compliance-of-wearing-monocentric-prospective-pilot-study-of-randomized-cross-over-design
#15
G W Herget, S Patermann, P C Strohm, J Zwingmann, P Eichelberger, N P Südkamp, A Hirschmüller
PURPOSE OF THE STUDY Various spine disorders are regularly treated by orthoses, and success of treatment depends on wearing these devices. In this study we examined the compliance, wear comfort, subjective stabilization and side effects associated with spinal orthoses using an individualized questionnaire and the Compact Short Form-12 Health Survey (SF-12). MATERIAL AND METHODS In this prospective pilot study of randomized cross-over design, twelve healthy volunteers with a mean age of 31.2 years wore three different types of orthoses, each for one week: A hyperextension brace (HB), a custom-made semirigid orthosis (SO) and a custom-made rigid orthosis (RO)...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28747468/sympathetic-neural-and-hemodynamic-responses-to-head-up-tilt-during-isoosmotic-and-hyperosmotic-hypovolemia
#16
Alexander M Posch, Adam J Luippold, Katherine M Mitchell, Karleigh E Bradbury, Robert W Kenefick, Samuel N Cheuvront, Nisha Charkoudian
We hypothesized that muscle sympathetic nerve activity (MSNA) during head-up tilt (HUT) would be augmented during exercise-induced (hyperosmotic) dehydration but not isoosmotic dehydration via an oral diuretic. We studied 26 young healthy subjects (7 female, 19 male) divided into three groups: euhydrated (EUH, n = 7), previously exercised in 40°C while maintaining hydration; dehydrated (DEH, n = 10), previously exercised in 40°C during which ~3% of body weight was lost via sweat loss; and diuretic (DIUR, n = 9), a group that did not exercise but lost ~3% of body weight via diuresis (furosemide, 80 mg by mouth)...
October 1, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28747449/loss-of-cutaneous-large-and-small-fibers-in-naive-and-l-dopa-treated-pd-patients
#17
Maria Nolano, Vincenzo Provitera, Fiore Manganelli, Rosa Iodice, Annamaria Stancanelli, Giuseppe Caporaso, Annamaria Saltalamacchia, Francesca Califano, Bernardo Lanzillo, Marina Picillo, Paolo Barone, Lucio Santoro
OBJECTIVE: To study small and large fiber pathology in drug-naive and l-dopa-treated patients affected by Parkinson disease (PD) in early phases, before the occurrence of neuropathic electrophysiologic abnormalities. METHODS: We enrolled 85 patients with idiopathic PD (male/female 49/36, age 61.3 ± 9.7 years) without electrophysiologic signs of neuropathy, including 48 participants naive to l-dopa treatment. All patients underwent clinical, functional, and morphologic assessment of sensory and autonomic nerves through dedicated questionnaires, quantitative sensory testing, sympathetic skin response, dynamic sweat test, and punch biopsies from glabrous and hairy skin...
August 22, 2017: Neurology
https://www.readbyqxmd.com/read/28707431/efficacy-of-a-proprietary-trigonella-foenum-graecum-l-de-husked-seed-extract-in-reducing-menopausal-symptoms-in-otherwise-healthy-women-a-double-blind-randomized-placebo-controlled-study
#18
RANDOMIZED CONTROLLED TRIAL
E Steels, M L Steele, M Harold, S Coulson
Trigonella foenum-graecum seed extract has demonstrated hormone modulatory activity, providing biological plausibility for relieving menopausal symptoms. The study aimed to assess efficacy of a standardized T. foenum-graecum de-husked seed extract in reducing menopausal symptoms in healthy aging women. The study was a double-blind, randomized, placebo-controlled trial that recruited 115 women aged 40 to 65 years of which 59 were allocated to active (n = 54 completed) and 56 to placebo (n = 50 completed)...
September 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28690083/analgesic-effects-of-preinjection-low-level-laser-light-therapy-lllt-before-third-molar-surgery-a-double-blind-randomized-controlled-trial
#19
Jacco G C Tuk, Arjen J van Wijk, Ine C Mertens, Zühal Keleş, Jérôme A H Lindeboom, Dan M J Milstein
OBJECTIVE: The aim of this study was to evaluate the analgesic effects of low-level laser therapy (LLLT) on preinjection sites in patients scheduled for third molar removal. STUDY DESIGN: This double-blind randomized controlled trial included 163 healthy patients undergoing third molar extractions. The study participants were randomly divided into an LLLT and a placebo group. Objective and subjective data sets were obtained from physiologic feedback (heart rate and sweat response) and a questionnaire, respectively...
May 4, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28679039/nonocclusive-sweat-collection-combined-with-chemical-isotope-labeling-lc-ms-for-human-sweat-metabolomics-and-mapping-the-sweat-metabolomes-at-different-skin-locations
#20
Kevin Hooton, Liang Li
Human sweat is an excellent biofluid candidate for metabolomics due to its noninvasive sample collection and relatively simple matrix. We report a simple and inexpensive method for sweat collection over a defined period (e.g., 24 h) based on the use of a nonocclusive style sweat patch adhered to a skin. This method was combined with differential chemical isotope labeling (CIL) LC-MS for mapping the metabolome profiles of sweat samples collected from skins of the left forearm, lower back, and neck of 20 healthy volunteers...
July 19, 2017: Analytical Chemistry
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