keyword
https://read.qxmd.com/read/38533067/validation-of-the-italian-version-of-the-neuroception-of-psychological-safety-scale-npss
#21
JOURNAL ARTICLE
Andrea Poli, Mario Miccoli
Research on the neuroscience of fear in both humans and non-humans has suggested that a lack of acquisition of safety cues might be a biological hallmark of posttraumatic stress disorder (PTSD). Danger perception, and in particular, feeling as one's own life is in danger, is thought to represent a major predictor of PTSD. Persistent danger perception is concurrently associated with a persistence of lack of safety. However, despite several research efforts, no validated psychometric tools exist regarding psychological safety as a unique core construct in the domain of a soothing-contentment system...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38532485/the-effects-of-visual-skills-training-on-cognitive-and-executive-functions-in-stroke-patients-a-systematic-review-with-meta-analysis
#22
REVIEW
Marc Niering, Johanna Seifert
The visual system and associated skills are of particular importance in stroke rehabilitation. The process of neuroplasticity involved in restoring cognitive function during this period is mainly based on anatomical and physiological mechanisms. However, there is little evidence-based knowledge about the effects of visual skills training that could be used to improve therapeutic outcomes in cognitive rehabilitation. A computerized systematic literature search was conducted in the PubMed, Medline, and Web of Science databases from 1 January 1960 to 11 Febuary 2024...
March 26, 2024: Journal of Neuroengineering and Rehabilitation
https://read.qxmd.com/read/38532374/12-month-follow-up-of-intensive-outpatient-treatment-for-ptsd-combining-prolonged-exposure-therapy-emdr-and-physical-activity
#23
JOURNAL ARTICLE
Julie Rendum Klaeth, Andreas Gjerde Jensen, Trude Julie Brynhildsvoll Auren, Stian Solem
BACKGROUND: Preliminary evidence shows promising treatment outcomes at short-term follow-up for intensive posttraumatic stress disorder (PTSD) treatment, but long-term follow-up studies are sparse. This study is a sequel to a previous pilot study and open trial, set out to investigate treatment outcomes at 12-month follow-up for outpatients completing an 8-day intensive treatment for PTSD. METHODS: All patients were diagnosed with PTSD and had multiple previous psychotherapy attempts (M = 3...
March 26, 2024: BMC Psychiatry
https://read.qxmd.com/read/38531721/effect-of-trauma-quality-improvement-initiatives-on-outcomes-and-costs-at-community-hospitals-a-scoping-review
#24
JOURNAL ARTICLE
Reba McIver, Mete Erdogan, Robin Parker, Allyson Evans, Robert Green, David Gomez, Tyler Johnston
BACKGROUND: Due to complex geography and resource constraints, trauma patients are often initially transported to community or rural facilities rather than a larger Level I or II trauma center. The objective of this scoping review was to synthesize evidence on interventions that improved the quality of trauma care and/or reduced healthcare costs at non-Level I or II facilities. METHODS: A scoping review was performed to identify studies implementing a Quality Improvement (QI) initiative at a non-major trauma center (i...
March 11, 2024: Injury
https://read.qxmd.com/read/38530675/early-physician-gestalt-versus-usual-screening-tools-for-the-prediction-of-sepsis-in-critically-ill-emergency-patients
#25
JOURNAL ARTICLE
Sarah K S Knack, Nathaniel Scott, Brian E Driver, Matthew E Prekker, Lauren Page Black, Charlotte Hopson, Ellen Maruggi, Olivia Kaus, Walker Tordsen, Michael A Puskarich
STUDY OBJECTIVE: Compare physician gestalt to existing screening tools for identifying sepsis in the initial minutes of presentation when time-sensitive treatments must be initiated. METHODS: This prospective observational study conducted with consecutive encounter sampling took place in the emergency department (ED) of an academic, urban, safety net hospital between September 2020 and May 2022. The study population included ED patients who were critically ill, excluding traumas, transfers, and self-evident diagnoses...
March 25, 2024: Annals of Emergency Medicine
https://read.qxmd.com/read/38530443/childhood-abuse-and-craving-in-methamphetamine-dependent-individuals-the-mediating-role-of-alexithymia
#26
JOURNAL ARTICLE
Jiajing Chen, Dong Mei Wang, Yang Tian, Rongrong Zhu, Yuqing Li, Lianglun Jia, Fabing Fu, Shanshan Tang, Xiaotao Wang, Li Wang, Xiang Yang Zhang
Individuals with a history of childhood abuse (CA, including neglect and abuse by caregivers before the age of 18 years) have more severe substance dependence problems than those without a history of childhood abuse. However, whether a history of CA exacerbates craving and the mechanism of this effect remain largely unknown. The aim of this study was to explore the role of alexithymia in the effects of CA on craving in a large sample of methamphetamine-dependent individuals based on latent vulnerability theory...
March 26, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38529909/long-term-outcomes-of-pediatric-traumatic-brain-injury-following-inpatient-rehabilitation
#27
JOURNAL ARTICLE
Timothy C Horn, Jennifer P Lundine, Tyler A Busch, Rebekah A Benkart, H Gerry Taylor, Christine H Koterba
OBJECTIVE: Assess residual disability in youth with traumatic brain injury (TBI) treated in a pediatric inpatient rehabilitation unit and examine associations of disability with inpatient status and measures of concurrent functioning. SETTING: Large, urban, quaternary care children's hospital in the Midwestern United States. PARTICIPANTS: Forty-five youth aged 6 to 18 years treated in an inpatient rehabilitation unit for mild-complicated to severe TBI at a minimum of 12 months postdischarge (mean = 3...
March 2024: Journal of Head Trauma Rehabilitation
https://read.qxmd.com/read/38529906/characterizing-health-literacy-and-its-correlates-among-individuals-with-traumatic-brain-injury-tbi-a-tbi-model-systems-study
#28
JOURNAL ARTICLE
Angelle M Sander, Monique R Pappadis, Shannon B Juengst, Luis Leon-Novelo, Esther Ngan, John D Corrigan, Laura E Dreer, Simon Driver, Anthony H Lequerica
OBJECTIVE: To characterize health literacy among individuals with traumatic brain injury (TBI) at least a year postinjury and to explore its relationship to sociodemographic variables, injury severity, and cognition. SETTING: Community following discharge from inpatient rehabilitation. PARTICIPANTS: In total, 205 individuals with complicated mild to severe TBI who completed follow-up as part of a national longitudinal study of TBI and completed a web-based health literacy measure...
March 2024: Journal of Head Trauma Rehabilitation
https://read.qxmd.com/read/38529377/a-rare-huge-bladder-inflammatory-myofibroblastic-tumor-treated-by-en-bloc-resection-with-diode-laser-a-case-report-and-literature-review
#29
Huisheng Yuan, Zilong Wang, Jiaxing Sun, Junhao Chu, Shishuai Duan, Muwen Wang
BACKGROUND: Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm with malignant potential. Bladder IMT is even rarer and mainly treated by surgical resection However, partial or radical cystectomy would affect the quality of life of patients due to major surgical trauma, and classical TURBT is hard to avoid intraoperative complications including obturator nerve reflex and bleeding etc. Therefore, the safe and effective better choice of surgical approaches become critical to bladder IMT...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38529316/impact-of-covid-status-and-blood-group-on-complications-in-patients-in-hemorrhagic-shock
#30
JOURNAL ARTICLE
Jason Bradley Brill, Krislynn M Mueck, Madeline E Cotton, Brian Tang, Mariela Sandoval, Lillian S Kao, Bryan A Cotton
OBJECTIVE: Among critically injured patients of various blood groups, we sought to compare survival and complication rates between COVID-19-positive and COVID-19-negative cohorts. BACKGROUND: SARS-CoV-2 infections have been shown to cause endothelial injury and dysfunctional coagulation. We hypothesized that, among patients with trauma in hemorrhagic shock, COVID-19-positive status would be associated with increased mortality and inpatient complications. As a secondary hypothesis, we suspected group O patients with COVID-19 would experience fewer complications than non-group O patients with COVID-19...
2024: Trauma Surgery & Acute Care Open
https://read.qxmd.com/read/38528512/effect-of-home-based-pulmonary-rehabilitation-on-exercise-capacity-in-post-covid-19-patients-a-randomized-controlled-trail
#31
RANDOMIZED CONTROLLED TRIAL
Tamer I Abo Elyazed, Laila A Alsharawy, Shaimaa E Salem, Nesma A Helmy, Ahmed Abd El-Moneim Abd El-Hakim
BACKGROUND: Coronavirus 2019 (COVID-19) is an epidemic condition that compromises various consequences. The goal of this study was to investigate the effect of home-based pulmonary rehabilitation on exercise capacity in patients with post COVID-19 syndrome. METHODS: The study was designed as a randomized control trial. A total of sixty-eight patients with post COVID-19 syndrome complaining of fatigue, dyspnea, and exercise intolerance participated in this study...
March 25, 2024: Journal of Neuroengineering and Rehabilitation
https://read.qxmd.com/read/38527944/major-low-energy-trauma-results-in-non-specific-immunoglobulin-generation-without-evidence-for-specific-autoantibody-production-a-prospective-cohort-study
#32
JOURNAL ARTICLE
Henrik Eckardt, Nicolas Bless, Ingmar Heijnen, Mario Morgenstern, Josephine Nehring, Andrea Kieninger-Gräfitsch, Martine Bouchenaki, Vanessa Durandin, Silke Purschke, Ina Schmidt, Loraine Pascale Kouba, Marten Trendelenburg, Eliska Potlukova
Cellular debris resulting from large trauma might overwhelm the scavenger mechanisms and lead to autoimmune reactions. We analysed whether a major well-defined trauma in humans induces laboratory signs of transient autoimmunity in the months after the insult. We included 50 patients with pertrochanteric femur fracture undergoing intramedullary nail osteosynthesis in a prospective cohort study and followed them at 3-4 days, 6 weeks, 12 weeks and 12 months postoperatively. By standard techniques, we assessed levels of total immunoglobulins, anti-nuclear antibodies (ANA), anti-cardiolipin antibodies, anti-dsDNA antibodies and anti-C1q antibodies, as well as antibodies against cytomegalovirus (CMV) as a control...
March 25, 2024: Scandinavian Journal of Immunology
https://read.qxmd.com/read/38526929/timing-of-decompressive-surgery-in-patients-with-acute-spinal-cord-injury-systematic-review-update
#33
JOURNAL ARTICLE
Michael G Fehlings, Laureen D Hachem, Lindsay A Tetreault, Andrea C Skelly, Joseph R Dettori, Erika D Brodt, Shay Stabler-Morris, Britt J Redick, Nathan Evaniew, Allan R Martin, Benjamin Davies, Farzin Farahbakhsh, James D Guest, Daniel Graves, Radha Korupolu, Stephen L McKenna, Brian K Kwon
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: Surgical decompression is a cornerstone in the management of patients with traumatic spinal cord injury (SCI); however, the influence of the timing of surgery on neurological recovery after acute SCI remains controversial. This systematic review aims to summarize current evidence on the effectiveness, safety, and cost-effectiveness of early (≤24 hours) or late (>24 hours) surgery in patients with acute traumatic SCI for all levels of the spine...
March 2024: Global Spine Journal
https://read.qxmd.com/read/38526286/ruxolitinib-improves-the-inflammatory-microenvironment-restores-glutamate-homeostasis-and-promotes-functional-recovery-after-spinal-cord-injury
#34
JOURNAL ARTICLE
Jiang Cao, Xiao Yu, Jingcheng Liu, Jiaju Fu, Binyu Wang, Chaoqin Wu, Sheng Zhang, Hongtao Chen, Zi Wang, Yinyang Xu, Tao Sui, Jie Chang, Xiaojian Cao
JOURNAL/nrgr/04.03/01300535-202419110-00030/figure1/v/2024-03-08T184507Z/r/image-tiff The inflammatory microenvironment and neurotoxicity can hinder neuronal regeneration and functional recovery after spinal cord injury. Ruxolitinib, a JAK-STAT inhibitor, exhibits effectiveness in autoimmune diseases, arthritis, and managing inflammatory cytokine storms. Although studies have shown the neuroprotective potential of ruxolitinib in neurological trauma, the exact mechanism by which it enhances functional recovery after spinal cord injury, particularly its effect on astrocytes, remains unclear...
November 1, 2024: Neural Regeneration Research
https://read.qxmd.com/read/38525594/adolescent-stress-induced-ventral-hippocampus-redox-dysregulation-underlies-behavioral-deficits-and-excitatory-inhibitory-imbalance-related-to-schizophrenia
#35
JOURNAL ARTICLE
Thamyris Santos-Silva, Caio Fábio Baeta Lopes, Doğukan Hazar Ülgen, Danielle A Guimarães, Francisco S Guimarães, Luciane Carla Alberici, Carmen Sandi, Felipe V Gomes
BACKGROUND AND HYPOTHESIS: Redox dysregulation has been proposed as a convergent point of childhood trauma and the emergence of psychiatric disorders, such as schizophrenia (SCZ). A critical region particularly vulnerable to environmental insults during adolescence is the ventral hippocampus (vHip). However, the impact of severe stress on vHip redox states and their functional consequences, including behavioral and electrophysiological changes related to SCZ, are not entirely understood...
March 25, 2024: Schizophrenia Bulletin
https://read.qxmd.com/read/38525582/the-burden-and-outcomes-of-firearm-injuries-at-two-district-level-emergency-centres-in-cape-town-south-africa-a-descriptive-analysis
#36
JOURNAL ARTICLE
L Bush, C Hendrikse, C Van Koningsbruggen, K Evans
BACKGROUND: In South Africa (SA), injuries are the second leading cause of years of healthy life lost, and interpersonal violence dominates the SA injury profile. Half of all injury-related deaths in SA are intentional, and firearms contribute to a quarter of these deaths. Injury surveillance systems are essential to develop, implement and monitor strategies that reduce preventable trauma. OBJECTIVES: To describe the burden of patients with firearm injuries and their outcomes at district-level emergency centres in the Western Cape...
February 13, 2024: South African Medical Journal
https://read.qxmd.com/read/38524192/experimental-and-virtual-testing-of-bone-implant-systems-equipped-with-the-ao-fracture-monitor-with-regard-to-interfragmentary-movement
#37
JOURNAL ARTICLE
Kerstin Wickert, Michael Roland, Annchristin Andres, Stefan Diebels, Bergita Ganse, Dorothea Kerner, Felix Frenzel, Thomas Tschernig, Manuela Ernst, Markus Windolf, Max Müller, Tim Pohlemann, Marcel Orth
Introduction: The management of fractured bones is a key domain within orthopedic trauma surgery, with the prevention of delayed healing and non-unions forming a core challenge. This study evaluates the efficacy of the AO Fracture Monitor in conjunction with biomechanical simulations to better understand the local mechanics of fracture gaps, which is crucial for comprehending mechanotransduction, a key factor in bone healing. Through a series of experiments and corresponding simulations, the study tests four hypotheses to determine the relationship between physical measurements and the predictive power of biomechanical models...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38523964/unveiling-the-surge-a-comprehensive-analysis-of-e-scooter-related-injuries-at-an-urban-level-1-trauma-center-in-vilnius-lithuania-2018-2021
#38
JOURNAL ARTICLE
Kristupas A Suslavičius, Simonas Utkus, Valentinas Uvarovas, Tomas Sveikata, Sigitas Ryliškis
Background The surge in electric scooter (e-scooter) adoption in 2019 fueled by sharing platforms has raised safety concerns, leading to an increased incidence of e-scooter-related injuries. Despite regulatory efforts, there has been a notable rise in accidents, prompting a comprehensive investigation. This study conducted at the Republican Vilnius University Hospital (RVUH), a level 1 trauma center, is one of the first in the Baltic States aiming to analyze the causes, severity, and frequency of e-scooter injuries from 2018 to 2021...
February 2024: Curēus
https://read.qxmd.com/read/38522814/the-neurophysiological-consequences-of-racism-related-stressors-in-black-americans
#39
REVIEW
E Kate Webb, Sierra E Carter, Kerry J Ressler, Negar Fani, Nathaniel G Harnett
Racism-related stressors, from experiences of both implicit and explicit racial discrimination to systemic socioeconomic disadvantage, have a cumulative impact on Black Americans' health. The present narrative review synthesizes peripheral (neuroendocrine and inflammation markers), psychophysiological (heart-rate variability, skin conductance), and neuroimaging (structural and functional) findings that demonstrate unique associations with racism-related stress. Emerging evidence reveals how racism-related stressors contribute to differential physiological and neural responses and may have distinct impacts on regions involved with threat and social processing...
March 22, 2024: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/38522614/neighborhood-resource-deprivation-as-a-predictor-of-bullying-perpetration-and-resource-driven-conduct-symptoms
#40
JOURNAL ARTICLE
Michael T Perino, Chad M Sylvester, Cynthia E Rogers, Joan L Luby, Deanna M Barch
OBJECTIVE: Resource deprivation is linked to systemic factors that disproportionately impact historically marginalized communities, and theoretical work suggests resource deprivation may increase risk for bullying behaviors. Bullying perpetration is an intransigent social problem and an early risk factor that perpetuates the school-to-prison pipeline. We explored how resource deprivation (family and neighborhood level metrics) was associated with early childhood bullying behaviors and clinician-rated symptoms of psychopathology, while accounting for other known risk factors (early life stressors, traumatic events, parental arrest, domestic violence)...
March 20, 2024: Journal of the American Academy of Child and Adolescent Psychiatry
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