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https://www.readbyqxmd.com/read/27885991/retraction-mmp-13-is-involved-in-oral-cancer-cell-metastasis
#1
Shun-Hong Huang, Ching-Hsuan Law, Ping-Hsueh Kuo, Ren-Yu Hu, Ching-Chieh Yang, Ting-Wen Chung, Ji-Min Li, Li-Hsun Lin, Yi-Chung Liu, En-Chi Liao, Yi-Ting Tsai, Yu-Shan Wei, Chi-Chen Lin, Chien-Wen Chang, Hsiu-Chuan Chou, Wen-Ching Wang, Margaret Dah-Tsyr Chang, Lu-Hai Wang, Hsing-Jien Kung, Hong-Lin Chan, Ping-Chiang Lyu
1.
July 26, 2016: Oncotarget
https://www.readbyqxmd.com/read/27828511/two-level-modulation-scheme-to-reduce-latency-for-optical-mobile-fronthaul-networks
#2
Jiun-Yu Sung, Chi-Wai Chow, Chien-Hung Yeh, Gee-Kung Chang
A system using optical two-level orthogonal-frequency-division-multiplexing (OFDM) - amplitude-shift-keying (ASK) modulation is proposed and demonstrated to reduce the processing latency for the optical mobile fronthaul networks. At the proposed remote-radio-head (RRH), the high data rate OFDM signal does not need to be processed, but is directly launched into a high speed photodiode (HSPD) and subsequently emitted by an antenna. Only a low bandwidth PD is needed to recover the low data rate ASK control signal...
October 31, 2016: Optics Express
https://www.readbyqxmd.com/read/27751415/validation-of-the-traditional-chinese-version-of-the-prolapse-quality-of-life-questionnaire-p-qol-in-a-mandarin-speaking-taiwanese-population
#3
Fei-Chi Chuang, Li-Ching Chu, Fu-Tsai Kung, Kuan-Hui Huang
OBJECTIVE: To validate the traditional Chinese translated version of the prolapse quality of life questionnaire (P-QOL). MATERIALS AND METHODS: The P-QOL questionnaire was translated into traditional Chinese characters and administered to women recruited from gynecologic outpatient clinics of Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. After the test-retest reliability and internal consistency were established in a pilot study, all participants completed the P-QOL questionnaire and were examined in the lithotomy position using the Pelvic Organ Prolapse Quantification System (POP-Q)...
October 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27742031/distinct-subpopulations-of-hepatitis-c-virus-infectious-cells-with-different-levels-of-intracellular-hepatitis-c-virus-core-protein
#4
Shu-Chi Wang, Jeng-Fu Yang, Chao-Ling Wang, Chung-Feng Huang, Yu-Yin Lin, Yi-You Chen, Chung-Ting Lo, Po-Yen Lee, Kuan-Ta Wu, Chia-I Lin, Meng-Hsuan Hsieh, Hung-Yi Chuang, Chi-Kung Ho, Ming-Lung Yu, Chia-Yen Dai
Chronic infection by hepatitis C virus (HCV) is a major risk factor for the development of hepatocellular carcinoma (HCC). Despite the clear clinical importance of virus-associated HCC, the underlying molecular mechanisms remain largely unclarified. Oxidative stress, in particular, DNA lesions associated with oxidative damage, plays a major role in carcinogenesis, and is strongly linked to the development of many cancers, including HCC. However, in identifying hepatocytes with HCV viral RNA, estimates of the median proportion of HCV-infected hepatocytes have been found as high as 40% in patients with chronic HCV infection...
October 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27741106/a-method-to-preserve-limbus-during-penetrating-keratoplasty-for-a-case-of-presumed-phaces-syndrome-with-sclerocornea-a-case-report
#5
Yi-Ju Ho, Hung-Chi Chen, Shirley H L Chang, Lung-Kung Yeh, David Hui-Kang Ma
BACKGROUND: Sclerocornea, a congenital corneal pathology characterized by bilateral scleralization of the cornea, which can be found in few cases with posterior fossa malformationshemangiomas-arterial anomalies-cardiac defects-eye abnormalities-sternal cleft and supraumbilical raphe (PHACES) syndrome. Presence of vascularization in peripheral cornea and smaller diameter of recipient cornea correlate to poor outcome of penetrating keratoplasty (PKP) in sclerocornea. Here we report a method to preserve limbus during PKP for small, irregular, and scleralized cornea...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27733774/time-lagging-interplay-effect-and-excess-risk-of-meteorological-mosquito-parameters-and-petrochemical-gas-explosion-on-dengue-incidence
#6
Ko Chang, Chaur-Dong Chen, Chien-Ming Shih, Tzu-Chi Lee, Ming-Tsang Wu, Deng-Chyang Wu, Yen-Hsu Chen, Chih-Hsing Hung, Meng-Chieh Wu, Chun-Chi Huang, Chien-Hung Lee, Chi-Kung Ho
In Kaohsiung, a metropolitan city in Taiwan at high risk of dengue epidemic, weather factors combined with an accidental petrochemical gas explosion (PGE) may affect mosquito‒human dynamics in 2014. Generalized estimating equations with lagged-time Poisson regression analyses were used to evaluate the effect of meteorological/mosquito parameters and PGE on dengue incidences (2000-2014) in Kaohsiung. Increased minimum temperatures rendered a 2- and 3-month lagging interactive effect on higher dengue risks, and higher rainfall exhibited a 1- and 2-month lagging interplay effect on lower risks (interaction, P ≤ 0...
October 13, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27681436/mammary-tumor-associated-rnas-impact-tumor-cell-proliferation-invasion-and-migration
#7
Sarah D Diermeier, Kung-Chi Chang, Susan M Freier, Junyan Song, Osama El Demerdash, Alexander Krasnitz, Frank Rigo, C Frank Bennett, David L Spector
Long non-coding RNAs (lncRNAs) represent the largest and most diverse class of non-coding RNAs, comprising almost 16,000 currently annotated transcripts in human and 10,000 in mouse. Here, we investigated the role of lncRNAs in mammary tumors by performing RNA-seq on tumor sections and organoids derived from MMTV-PyMT and MMTV-Neu-NDL mice. We identified several hundred lncRNAs that were overexpressed compared to normal mammary epithelium. Among these potentially oncogenic lncRNAs we prioritized a subset as Mammary Tumor Associated RNAs (MaTARs) and determined their human counterparts, hMaTARs...
September 27, 2016: Cell Reports
https://www.readbyqxmd.com/read/27677117/theoretical-investigation-of-low-detection-sensitivity-for-underivatized-carbohydrates-in-esi-and-maldi
#8
Jien-Lian Chen, Chuping Lee, I-Chung Lu, Chia-Lung Chien, Yuan-Tseh Lee, Wei-Ping Hu, Chi-Kung Ni
Electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) mainly generate protonated ions from peptides and proteins but sodiated (or potassiated) ions from carbohydrates. The ion intensities of sodiated (or potassiated) carbohydrates generated by ESI and MALDI are generally lower than those of protonated peptides and proteins. Ab initio calculations and transition state theory were used to investigate the reasons for the low detection sensitivity for underivatized carbohydrates...
September 27, 2016: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/27650655/what-is-the-predictor-of-surgical-mortality-in-adult-colorectal-perforation-the-clinical-characteristics-and-results-of-a-multivariate-logistic-regression-analysis
#9
Chao-Wen Hsu, Jui-Ho Wang, Ya-Hsin Kung, Min-Chi Chang
PURPOSE: Colorectal perforations are a serious condition associated with a high mortality. The aim of this study was to describe the clinical characteristics and identify predictors for the surgical mortality in adult patients with colorectal perforation, thereby achieving better outcomes. METHODS: A retrospective study of adult patients diagnosed with colorectal perforation operated was performed. The clinical variables that might influence the surgical mortality were first analyzed, and the significant variables were then analyzed using a logistic regression model...
September 20, 2016: Surgery Today
https://www.readbyqxmd.com/read/27624347/corrigendum-knocking-down-of-heat-shock-protein-27-directs-differentiation-of-functional-glutamatergic-neurons-from-placenta-derived-multipotent-cells
#10
Yu-Che Cheng, Chi-Jung Huang, Yih-Jing Lee, Lu-Tai Tien, Wei-Chi Ku, Raymond Chien, Fa-Kung Lee, Chih-Cheng Chien
No abstract text is available yet for this article.
2016: Scientific Reports
https://www.readbyqxmd.com/read/27604617/12th-winfocus-world-congress-on-ultrasound-in-emergency-and-critical-care
#11
Yahya Acar, Onur Tezel, Necati Salman, Erdem Cevik, Margarita Algaba-Montes, Alberto Oviedo-García, Mayra Patricio-Bordomás, Mustafa Z Mahmoud, Abdelmoneim Sulieman, Abbas Ali, Alrayah Mustafa, Ihab Abdelrahman, Mustafa Bahar, Osama Ali, H Lester Kirchner, Gregor Prosen, Ajda Anzic, Paul Leeson, Maryam Bahreini, Fatemeh Rasooli, Houman Hosseinnejad, Gabriel Blecher, Robert Meek, Diana Egerton-Warburton, Edina Ćatić Ćuti, Stanko Belina, Tihomir Vančina, Idriz Kovačević, Nadan Rustemović, Ikwan Chang, Jin Hee Lee, Young Ho Kwak, Do Kyun Kim, Chi-Yung Cheng, Hsiu-Yung Pan, Chia-Te Kung, Ela Ćurčić, Ena Pritišanac, Ivo Planinc, Marijana Grgić Medić, Radovan Radonić, Abiola Fasina, Anthony J Dean, Nova L Panebianco, Patricia S Henwood, Oliviero Fochi, Moreno Favarato, Ezio Bonanomi, Ivan Tomić, Youngrock Ha, Hongchuen Toh, Elizabeth Harmon, Wilma Chan, Cameron Baston, Gail Morrison, Frances Shofer, Angela Hua, Sharon Kim, James Tsung, Isa Gunaydin, Zeynep Kekec, Mehmet Oguzhan Ay, Jinjoo Kim, Jinhyun Kim, Gyoosung Choi, Dowon Shim, Ji-Han Lee, Jana Ambrozic, Katja Prokselj, Miha Lucovnik, Gabrijela Brzan Simenc, Asta Mačiulienė, Almantas Maleckas, Algimantas Kriščiukaitis, Vytautas Mačiulis, Andrius Macas, Sharad Mohite, Zoltan Narancsik, Hugon Možina, Sara Nikolić, Jan Hansel, Rok Petrovčič, Una Mršić, Simon Orlob, Markus Lerchbaumer, Niklas Schönegger, Reinhard Kaufmann, Chun-I Pan, Chien-Hung Wu, Sarah Pasquale, Stephanie J Doniger, Sharon Yellin, Gerardo Chiricolo, Maja Potisek, Borut Drnovšek, Boštjan Leskovar, Kristine Robinson, Clara Kraft, Benjamin Moser, Stephen Davis, Shelley Layman, Yusef Sayeed, Joseph Minardi, Irmina Sefic Pasic, Amra Dzananovic, Anes Pasic, Sandra Vegar Zubovic, Ana Godan Hauptman, Ana Vujaklija Brajkovic, Jaksa Babel, Marina Peklic, Vedran Radonic, Luka Bielen, Peh Wee Ming, Nur Hafiza Yezid, Fatahul Laham Mohammed, Zainal Abidin Huda, Wan Nasarudin Wan Ismail, W Yus Haniff W Isa, Hashairi Fauzi, Praveena Seeva, Mohd Zulfakar Mazlan
A1 Point-of-care ultrasound examination of cervical spine in emergency departmentYahya Acar, Onur Tezel, Necati SalmanA2 A new technique in verifying the placement of a nasogastric tube: obtaining the longitudinal view of nasogastric tube in addition to transverse view with ultrasoundYahya Acar, Necati Salman, Onur Tezel, Erdem CevikA3 Pseudoaneurysm of the femoral artery after cannulation of a central venous line. Should we always use ultrasound in these procedures?Margarita Algaba-Montes, Alberto Oviedo-García, Mayra Patricio-BordomásA4 Ultrasound-guided supraclavicular subclavian vein catheterization...
September 2016: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/27565889/is-endoscopic-treatment-beneficial-in-patients-with-clinically-suspicious-of-common-bile-duct-stones-but-no-obvious-filling-defects-during-the-ercp-examination
#12
Po-Hung Chiang, Kwok-Hung Lai, Tzung-Jiun Tsai, Kung-Hung Lin, Kai-Ming Wang, Sung-Shuo Kao, Wei-Chih Sun, Jin-Shiung Cheng, Ping-I Hsu, Wei-Lun Tsai, Wen-Chi Chen, Yun-Da Li, E-Ming Wang, Huey-Shyan Lin, Hoi-Hung Chan
BACKGROUND: Sometimes, no definite filling defect could be found by cholangiogram (ERC) during the endoscopic retrograde cholangio-pancreatiographic (ERCP) exam; even prior images had evidence of common bile duct stones (CBDS). We aimed in estimating the positive rate of extraction of CBDS who had treated by endoscopic sphincterotomy/endoscopic papillary balloon dilation (EST/EPBD) with negative ERC finding. METHODS: One hundred forty-one patients with clinically suspicious of CBDS but negative ERC, who had received EST/EPBD treatments was enrolled...
August 26, 2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27529880/cost-effective-kernel-ridge-regression-implementation-for-keystroke-based-active-authentication-system
#13
Pei-Yuan Wu, Chi-Chen Fang, Jien Morris Chang, Sun-Yuan Kung
In this paper, a fast kernel ridge regression (KRR) learning algorithm is adopted with O(N) training cost for large-scale active authentication system. A truncated Gaussian radial basis function (TRBF) kernel is also implemented to provide better cost-performance tradeoff. The fast-KRR algorithm along with the TRBF kernel offers computational advantages over the traditional support vector machine (SVM) with Gaussian-RBF kernel while preserving the error rate performance. Experimental results validate the cost-effectiveness of the developed authentication system...
August 2, 2016: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/27501302/the-critical-role-of-early-dengue-surveillance-and-limitations-of-clinical-reporting-implications-for-non-endemic-countries
#14
Jui-Hung Kao, Chaur-Dong Chen, Zheng-Rong Tiger Li, Ta-Chien Chan, Tsung-Hwa Tung, Yin-Hsia Chu, Hau-Yuan Cheng, Jien-Wei Liu, Fuh-Yuan Shih, Pei-Yun Shu, Chien-Chou Lin, Wu-Hsiung Tsai, Chia-Chi Ku, Chi-Kung Ho, Chwan-Chuen King
The increasing dengue burden and epidemic severity worldwide have highlighted the need to improve surveillance. In non-endemic areas such as Taiwan, where outbreaks start mostly with imported cases from Southeast Asia, a closer examination of surveillance dynamics to detect cases early is necessary. To evaluate problems with dengue surveillance and investigate the involvement of different factors at various epidemic stages, we investigated 632 laboratory-confirmed indigenous dengue cases in Kaohsiung City, Taiwan during 2009-2010...
2016: PloS One
https://www.readbyqxmd.com/read/27477870/resistin-reinforces-interferon-%C3%AE-3-to-eliminate-hepatitis-c-virus-with-fine-tuning-from-retn-single-nucleotide-polymorphisms
#15
Ming-Ling Chang, Kung-Hao Liang, Cheng-Lung Ku, Chia-Chi Lo, Ya-Ting Cheng, Chen-Ming Hsu, Chau-Ting Yeh, Cheng-Tang Chiu
The effect of resistin (RETN) on the response to anti-HCV therapy remains unclear. A prospective cohort study was performed using 655 consecutive HCV patients, of whom 513 had completed a course of interferon-based therapy. Multivariate and GEE analyses revealed four RETN single-nucleotide polymorphisms (SNPs), rs34861192, rs3219175, rs3745367 and rs1423096, to be synergistically associated with resistin levels. After adjusting for co-factors such as interferon λ-3 (IFNL3)-rs12979860, the resistin level and the hyper-resistinemic genotype at the 4 RETN SNPs were positively and negatively associated with a sustained virological response (SVR), respectively...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27466427/the-ubiquitin-ligase-itch-and-ubiquitination-regulate-bfrf1-mediated-nuclear-envelope-modification-for-epstein-barr-virus-maturation
#16
Chung-Pei Lee, Guan-Ting Liu, Hsiu-Ni Kung, Po-Ting Liu, Yen-Tzu Liao, Lu-Ping Chow, Ling-Shih Chang, Yu-Hsin Chang, Chou-Wei Chang, Wen-Chi Shu, Annie Angers, Antonella Farina, Su-Fang Lin, Ching-Hwa Tsai, Fadila Bouamr, Mei-Ru Chen
UNLABELLED: The cellular endosomal sorting complex required for transport (ESCRT) was recently found to mediate important morphogenesis processes at the nuclear envelope (NE). We previously showed that the Epstein-Barr virus (EBV) BFRF1 protein recruits the ESCRT-associated protein Alix to modulate NE structure and promote EBV nuclear egress. Here, we uncover new cellular factors and mechanisms involved in this process. BFRF1-induced NE vesicles are similar to those observed following EBV reactivation...
October 15, 2016: Journal of Virology
https://www.readbyqxmd.com/read/27450026/comparison-of-the-clinical-outcomes-of-transobturator-and-single-incision-slings-for%C3%A2-stress%C3%A2-urinary-incontinence
#17
Ling-Ying Wu, Tsai-Hwa Yang, Fu-Tsai Kung, Fei-Chi Chuang, Kuan-Hui Huang
The aim of this study was to compare the clinical outcomes of anti-incontinence surgeries employing the transobturator sling and single-incision sling (SIS). Our hypothesis is that the outcome of the SIS is not inferior to the obturator sling. This retrospective study reviewed the medical records of patients who underwent anti-incontinence surgery with the transobturator sling or SIS from July 2005 to November 2014. Patients who underwent concomitant pelvic organ reconstruction with an artificial mesh were excluded...
July 2016: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/27444754/knocking-down-of-heat-shock-protein-27-directs-differentiation-of-functional-glutamatergic-neurons-from-placenta-derived-multipotent-cells
#18
Yu-Che Cheng, Chi-Jung Huang, Yih-Jing Lee, Lu-Tai Tien, Wei-Chi Ku, Raymond Chien, Fa-Kung Lee, Chih-Cheng Chien
This study presents human placenta-derived multipotent cells (PDMCs) as a source from which functional glutamatergic neurons can be derived. We found that the small heat-shock protein 27 (HSP27) was downregulated during the neuronal differentiation process. The in vivo temporal and spatial profiles of HSP27 expression were determined and showed inverted distributions with neuronal proteins during mouse embryonic development. Overexpression of HSP27 in stem cells led to the arrest of neuronal differentiation; however, the knockdown of HSP27 yielded a substantially enhanced ability of PDMCs to differentiate into neurons...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27306427/formation-of-metal-related-ions-in-matrix-assisted-laser-desorption-ionization
#19
Chuping Lee, I-Chung Lu, Hsu Chen Hsu, Hou-Yu Lin, Sheng-Ping Liang, Yuan-Tseh Lee, Chi-Kung Ni
In a study of the metal-related ion generation mechanism in matrix-assisted laser desorption ionization (MALDI), crystals of matrix used in MALDI were grown from matrix- and salt-containing solutions. The intensities of metal ion and metal adducts of the matrix ion obtained from unwashed crystals were higher than those from crystals washed with deionized water, indicating that metal ions and metal adducts of the matrix ions are mainly generated from the surface of crystals. The contributions of preformed metal ions and metal adducts of the matrix ions inside the matrix crystals were minor...
September 2016: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/27284246/non-small-cell-lung-cancer-cells-combat-epidermal-growth-factor-receptor-tyrosine-kinase-inhibition-through-immediate-adhesion-related-responses
#20
Hsian-Yu Wang, Min-Kung Hsu, Kai-Hsuan Wang, Ching-Ping Tseng, Feng-Chi Chen, John T-A Hsu
BACKGROUND: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), such as gefitinib, erlotinib, and afatinib, have greatly improved treatment efficacy in non-small cell lung cancer (NSCLC) patients with drug-sensitive EGFR mutations. However, in some TKI responders, the benefits of such targeted therapies are limited by the rapid development of resistance, and strategies to overcome this resistance are urgently needed. Studies of drug resistance in cancer cells typically involve long term in vitro induction to obtain stably acquired drug-resistant cells followed by elucidation of resistance mechanisms, but the immediate responses of cancer cells upon drug treatment have been ignored...
2016: OncoTargets and Therapy
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