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Upper gastrointestinal bleeding

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https://www.readbyqxmd.com/read/29149919/gastrointestinal-and-hepatic-disease-in-vasculitis
#1
REVIEW
Eric Anderson, Neel Gakhar, Courtney Stull, Liron Caplan
Vasculitis is an inflammatory condition that targets the blood vessels, which may occur in isolation or as a component of a systemic inflammatory condition. Although many of the vasculitides can directly affect the organs of the gastrointestinal system, some types exhibit a proclivity for certain gastrointestinal and hepatic organs. Often a patient presents with nonspecific symptoms, delaying the diagnosis and treatment of the underlying vasculitis. Vasculitis can also present with severe manifestations, such as upper gastrointestinal bleeds and bowel perforation...
February 2018: Rheumatic Diseases Clinics of North America
https://www.readbyqxmd.com/read/29142512/non-steroidal-anti-inflammatory-drug-induced-enteropathy
#2
REVIEW
Sung Jae Shin, Choong-Kyun Noh, Sun Gyo Lim, Kee Myung Lee, Kwang Jae Lee
Non-steroidal anti-inflammatory drugs (NSAIDs) are well known to be associated with serious upper gastrointestinal complications, such as peptic ulcer, bleeding, perforation, and obstruction. Recently, attention has been mainly focused on the small bowel injuries caused by NSAIDs, and new endoscopic techniques such as capsule endoscopy and double balloon endoscopy can help in detecting such injuries. This article reviewed the epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment of small bowel injuries caused by NSAIDs...
October 2017: Intestinal Research
https://www.readbyqxmd.com/read/29124127/effectiveness-of-tc-325-hemospray-for-treatment-of-diffuse-or-refractory-upper-gastrointestinal-bleeding-a-single-center-experience
#3
Oscar Cahyadi, Markus Bauder, Benjamin Meier, Karel Caca, Arthur Schmidt
Background and study aims:  TC-325 (Hemospray, Cook Medical) is a powder agent for endoscopic hemostasis in patients with upper gastrointestinal bleeding (UGIB). Although most publications are based on case-reports and retrospective studies, data on efficacy are promising. Here we report our experience with TC-325 for diffuse or refractory UGIB. Patients and methods:  Data on patients receiving TC-325 for endoscopic hemostasis from November 2013 to February 2017 at our center were analyzed retrospectively...
November 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29124121/patients-comorbidities-reduce-the-clinical-value-of-emergency-colonoscopy-results-of-a-retrospective-cohort-study
#4
Cristiano Cremone, Anouk Esch, Charlotte Gagniere, Alessandro Fugazza, Faria Mesli, Michael Levy, Aurelien Amiot, Alexis Laurent, Yann LeBaleur, Francois Hemery, Nicolas De'Angelis, Francesco Brunetti, Iradj Sobhani
Background and study aims:  Urgent endoscopy is often used to diagnose and sometimes treat acute upper gastrointestinal syndromes (hemorrhage, toxic ingestion, and occlusion). However, its suitability concerning the management of lower gastrointestinal conditions in emergency circumstances is controversial. Patients and methods:  We studied the role of emergency colonoscopy in diagnosis and treatment of all consecutive patients presenting with acute lower gastrointestinal symptoms referred to our hospital on an emergency basis...
November 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/29118868/efficacy-of-video-capsule-endoscopy-in-the-management-of-suspected-small-bowel-bleeding-in-patients-with-continuous-flow-left-ventricular-assist-devices
#5
Thomas A Zikos, Jennifer Pan, Berkeley Limketkai, Dipanjan Banerjee, Nielsen Fernandez-Becker
Background: Continuous flow left ventricular assist device (CF-LVAD) patients have a high prevalence of gastrointestinal bleeding from the small bowel. Video capsule endoscopy (VCE) is often used for diagnosis in these patients, but efficacy has yet to be determined. In this study, we evaluated the efficacy of VCE in the management of CF-LVAD patients with suspected small bowel bleeding by comparing to a non-VCE CF-LVAD control group. Methods: We retrospectively reviewed the charts of all patients with CF-LVADs implanted at Stanford Hospital from January 2010 to October 2015...
October 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29106288/localized-gastrointestinal-amyloidosis-presenting-with-protein-losing-enteropathy-and-massive-hemorrhage
#6
Bárbara Corrêa, Cristiane Kibune Nagasako, Ciro Garcia Montes, Marlone Cunha-Silva, Maria Aparecida Mesquita
Amyloidosis of the gastrointestinal tract is usually a systemic disease. Localized gastrointestinal amyloidosis without evidence of extraintestinal involvement or an associated plasma cell dyscrasia is uncommon and does not usually cause death. We report a case of a patient with localized gastrointestinal amyloidosis who presented with protein-losing enteropathy and a fatal upper gastrointestinal bleed.
November 6, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29103333/arterial-lactate-does-not-predict-outcome-better-than-existing-risk-scores-in-upper-gastrointestinal-bleeding
#7
Line Aabel Stokbro, Ove B Schaffalitzky de Muckadell, Stig Borbjerg Laursen
OBJECTIVE: Upper gastrointestinal bleeding (UGIB) is a frequent medical emergency and several scoring systems are developed to help risk-stratify patients. We aimed to investigate if elevated arterial lactate (AL) was associated with 30-day mortality, need for hospital-based intervention, or rebleeding. Furthermore, we compared the performance of AL with existing scoring systems and examined if incorporation of AL could improve their predictive ability. MATERIALS AND METHODS: Retrospective cohort study of 331 consecutive patients admitted with UGIB during a one-year period...
November 6, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29102618/a-rare-cause-of-an-upper-gastrointestinal-bleed
#8
Anusha Shirwaikar Thomas, Mary R Schwartz, Leila Neshatian
No abstract text is available yet for this article.
November 1, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29101296/stopping-antithrombotic-therapy-after-acute-upper-gastrointestinal-bleeding-is-associated-with-reduced-survival
#9
Keith Siau, Jack L Hannah, James Hodson, Monika Widlak, Neeraj Bhala, Tariq H Iqbal
INTRODUCTION: Antithrombotic drugs are often stopped following acute upper gastrointestinal bleeding (AUGIB) and frequently not restarted. The practice of antithrombotic discontinuation on discharge and its impact on outcomes are unclear. OBJECTIVE: To assess whether restarting antithrombotic therapy, prior to hospital discharge for AUGIB, affected clinical outcomes. DESIGN: Retrospective cohort study. SETTING: University hospital between May 2013 and November 2014, with median follow-up of 259 days...
November 3, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29100227/utility-of-the-shock-index-for-risk-stratification-in-patients-with-acute-upper-gastrointestinal-bleeding
#10
Supannee Rassameehiran, Jirapat Teerakanok, Sakolwan Suchartlikitwong, Kenneth Nugent
OBJECTIVES: Patients with upper gastrointestinal bleeding (UGIB) frequently require hospitalization, and a small but significant percentage of these patients have adverse outcomes. Risk-scoring tools can help clinicians organize care and make predictions about outcomes. The shock index (heart rate divided by systolic blood pressure) has been used in multiple acute disorders and has the potential to identify patients with UGIB who are at risk for adverse outcomes. METHODS: We retrospectively reviewed the electronic medical records of patients admitted with UGIB between January 1, 2012 and December 31, 2015...
November 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/29099778/upper-gastrointestinal-bleeding-in-children-a-tertiary-united-kingdom-children-s-hospital-experience
#11
Omar Nasher, David Devadason, Richard J Stewart
The aim of this study was to review the aetiology, presentation and management of these patients with upper gastrointestinal bleeding (UGIB) at a tertiary children's unit in the United Kingdom. This was a retrospective single-institution study on children (<16 years) who presented with acute UGIB over a period of 5 years using known International Classification of Diseases (ICD) codes. A total of 32 children (17 males, 15 females) were identified with a total median age at presentation of 5.5 years. The majority (24/32) of patients presented as an emergency...
November 3, 2017: Children
https://www.readbyqxmd.com/read/29095860/red-cell-distribution-width-as-a-novel-marker-for-predicting-high-risk-from-upper-gastro-intestinal-bleeding-patients
#12
Kyeong Ryong Lee, Sang O Park, Sin Young Kim, Dae Young Hong, Jong Won Kim, Kwang Je Baek, Dong Hyuk Shin, Young Hwan Lee
BACKGROUND: In upper gastrointestinal bleeding (UGIB) patients, early risk stratification allows appropriate therapy that may be helpful for reducing morbidity and mortality. OBJECTIVES: to evaluate the efficacy of red-cell distribution width (RDW) for prediction of high-risk in UGIB patients. METHODS: We conducted a clinical retrospective observational study based on data for UGIB patients from 2012 to 2013. The primary outcome was the high-risk UGIB, defined as those who required urgent intervention and/or 30-days mortality...
2017: PloS One
https://www.readbyqxmd.com/read/29095285/upper-and-lower-gastrointestinal-endoscopies-in-patients-over-85-years-of-age-risk-benefit-evaluation-of-a-longitudinal-cohort
#13
Raphaël Clere-Jehl, Mickael Schaeffer, Thomas Vogel, Michele Kiesmann, Jean-Louis Pasquali, Emmanuel Andres, Anne Bourgarit, Bernard Goichot
After age 85, upper and lower gastrointestinal (GI) endoscopy may be indicated in 5% to 10% of inpatients, but the risk-benefit ratio is unknown. We studied patients older than 85 years undergoing upper and lower GI endoscopy.We analyzed a retrospective cohort of inpatients older than 85 years between 2004 and 2012, all explored by upper and complete lower GI endoscopy. Initial indications, including iron deficiency anemia (IDA), other anemias, GI bleeding, weight loss, and GI symptoms, were noted, as were endoscopy or anesthesia complications, immediate endoscopic diagnosis, and the ability to modify the patients' therapeutics...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29094033/inferior-mesenteric-arteriovenous-fistula
#14
Seunghun Lee, Jooweon Chung, Byungkwon Ahn, Seunghyun Lee, Sunguhn Baek
Arteriovenous fistula (AVF) involving the inferior mesenteric artery and vein is very rare with only 33 cases described in the literature and may be of congenital or acquired (iatrogenic or traumatic) or idiopathic etiology. The pathophysiology of AVF that acts as a left-to-right shunt has accounted for clinical signs and symptoms associated with ischemic colitis, portal hypertension, and heart failure. A low incidence and nonspecific clinical signs and symptoms such as abdominal pain, thrill and mass, lower and upper gastrointestinal bleeding make it difficult to establish a diagnosis of inferior mesenteric AVF...
October 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29093591/-gastric-hemangioma-as-a-cause-of-upper-gastrointestinal-bleeding
#15
Jorge Espinoza-Ríos, Maria C Ferrufino-Schmidt, Eduar Bravo Paredes, Jaime Cok Garcia, José Pinto Valdivia, Martin Tagle Arróspide, Alejandro Bussalleu Rivera
Gastric hemangioma as a cause of upper gastrointestinal bleeding (UGIB) is a rare event. We present the case of an 83 years old male with a history of abdominal pain, vomiting and melena, along with an 8 Kg weight loss. The upper gastrointestinal endoscopy showed an elevated, ulcerated lesion in the gastric antrum with a visible vessel, for which he receives endoscopic therapy. In the abdominal computed tomography, a contrast enhancing, well-circumscribed mass attached to the gastric wall is observed. Due to the persistence of the UGIB, the patient suffers hemodynamic decompensation and undergoes exploratory laparotomy, where a vascularized mass is found...
July 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29089686/acute-ischemic-pancreatitis-a-rare-complication-of-empirical-gastroduodenal-artery-embolization
#16
Wei Ming Chua, Nanda Venkatanarasimha, Karthikeyan Damodharan
Empirical embolization of the gastroduodenal artery (GDA) is accepted as a safe and effective treatment option for endoscopy-refractory nonvariceal upper gastrointestinal bleeding (UGIB) in patients with high surgical risk. Nontarget embolization is a recognized complication of transarterial embolization, however, symptomatic pancreatic injury is extremely rare. We report a patient who developed acute ischemic pancreatitis immediately after embolization of the GDA, which was confirmed intraoperatively. Interventionists as well as referring clinicians need to be aware of this rare but life threatening complication...
July 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/29082854/acute-myocardial-infarction-associated-with-thrombotic-microangiopathy-following-a-hump-nosed-viper-bite-a-case-report
#17
Nipun Lakshitha de Silva, Lalindra Gooneratne, Eranga Wijewickrama
BACKGROUND: Hump-nosed viper bite is the commonest cause of venomous snakebite in Sri Lanka. Despite initially being considered a moderately venomous snake more recent reports have revealed that it could cause significant systemic envenoming leading to coagulopathy and acute kidney injury. However, myocardial infarction was not reported except for a single case, which occurred immediately after the snakebite. CASE PRESENTATION: A 50-year-old previously healthy Sri Lankan woman had a hump-nosed viper bite with no evidence of systemic envenoming during initial hospital stay...
October 30, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29082743/massive-upper-gastrointestinal-bleeding-due-to-a-dieulafoy-s-lesion-inside-a-duodenal-diverticulum
#18
Lucía Relea Pérez, Marta Magaz Martínez, Fernando Pons Renedo
In relation to the article published in this journal by Valdivielso Cortázar et al., we have recently diagnosed a massive digestive hemorrhage secondary to a Dieulafoy's lesion inside a duodenal diverticulum. This was successfully treated with endoscopy.
October 30, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29076685/causes-of-lower-gastrointestinal-bleeding-on-colonoscopy
#19
Attique-Ur-Rehman Jehangiri, Rahid Gul, Rania Hadayat, Adil Naseer Khan, Zabiullah, Liaqat Khursheed
BACKGROUND: Bleeding from anus is usually referred as rectal bleeding but actually rectal bleeding is defined as bleeding from lower colon or rectum, which means bleeding from a place distal to ligament of Treitz. This study was conducted to determine the frequency of different causes of rectal bleeding in patients at Ayub Teaching Hospital, Abbottabad. METHODS: One hundred and seventy-five patients with evidence of rectal bleed, without gender discrimination were selected by non-probability convenient sampling from the out-patient department and general medical wards...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29067041/paediatric-inflammatory-bowel-disease-clinical-presentation-and-disease-location
#20
Danish Abdul Aziz, Maryum Moin, Atif Majeed, Kamran Sadiq, Abdul Gaffar Biloo
OBJECTIVE: To determine different clinical presentationsand disease location demarcatedby upper and lower gastrointestinal endoscopyand relevant histopathologyin children diagnosed with inflammatory bowel disease (IBD). METHODS: This is 5 years (2010 to 2015) retrospective studyconducted at the Aga Khan University Hospitalenrolling65admitted children between 6 months to 15years from either gender, diagnosed with IBD on clinical presentation, endoscopy and biopsy...
July 2017: Pakistan Journal of Medical Sciences Quarterly
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