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Sex differences

Michael Schmid, Claus Steinlein
A detailed cytogenetic study on the leaf litter frog Eleutherodactylus johnstonei from 14 different Caribbean islands and the mainlands of Venezuela and Guyana revealed the existence of multimorphic XY♂/XX♀ sex chromosomes 14. Their male sex determination and development depends either on the presence of 2 telocentric chromosomes 14 (XtYt), or on 1 submetacentric chromosome 14 (Xsm) plus 1 telocentric chromosome 14 (Yt), or on the presence of 2 submetacentric chromosomes 14 (XsmYsm). The female sex determination and development requires either the presence of 2 telocentric chromosomes 14 (XtXt) or 2 submetacentric chromosomes 14 (XsmXsm)...
March 16, 2018: Cytogenetic and Genome Research
Stacy A Voils, Mohamed H Shahin, Timothy J Garrett, Reginald F Frye
OBJECTIVE: Incidence of venous thromboembolism (VTE) in critically ill patients remains unacceptably high despite widespread use of thromboprophylaxis. A systems biology approach may be useful in understanding disease pathology and predicting response to treatment. Metabolite profile under specific environmental conditions provides the closest link to phenotype, but the relationship between metabolomics and risk of VTE in critically ill patients is unknown. In this study, metabolomics signatures are compared in patients with and without VTE...
March 8, 2018: Thrombosis Research
G Fenu, L Lorefice, L Loi, V Sechi, F Contu, G Coghe, J Frau, G Spinicci, M A Barracciu, M G Marrosu, E Cocco
BACKGROUND: Paediatric onset multiple sclerosis (POMS) is associated with reduced brain and deep grey matter volume in comparison with that in healthy controls and individuals with adult onset multiple sclerosis (AOMS). The aim of our study was to evaluate the impact of POMS on adult brain volume with adjustment for other parameters, such as disease duration. PATIENTS AND METHODS: We recruited 20 POMS and 40 AOMS patients and 20 healthy controls matched for age and sex...
March 6, 2018: Multiple Sclerosis and related Disorders
Cheng-Chen Pan, Christophe Maïano, Alexandre J S Morin
BACKGROUND: Little research has looked at the associations between sex, weight status and culture, and the physical self-perceptions and body dissatisfaction of individuals with intellectual disabilities (ID) involved in Special Olympics (SO) sports. AIMS: To examine sex- (male vs female), weight status- (non-overweight/obese vs. overweight/obese), and culture-based (North American vs. Asian) differences in physical self-concept and body dissatisfaction among SO athletes...
March 12, 2018: Research in Developmental Disabilities
Nadia J Sweis
OBJECTIVES: To highlight the physical, psychological, social, and economic reasons related to sex differences in smoking behaviors in Jordan. METHODS: A cross-sectional questionnaire-based survey was conducted among Jordanian adult smokers. RESULTS: Sex was a significant predictor of physical reasons related to smoking; when controlling for other factors (t765 = 5.027; P < 0.001), women were more affected by physical factors than were men...
March 12, 2018: Value in Health Regional Issues
Wenge Chen, Yunlong Cheng, Jianzhong Chen, Jiahang Chen, Kai Jiang, Yuyang Zhou, Lee Jia
Mifepristone (RU486) is developed originally as a contraceptive used by hundreds of millions of women world-wide, and also reported as a safe and long-term psychotic depressant, or as a cancer chemotherapeutic agent used by both sexes. In our preliminary study aimed at developing mifepristone as a cancer metastatic chemopreventive, we coincidentally observed that blood mifepristone concentrations in female rats seem to be higher than those in male ones post administration. To substantiate if the pharmacokinetic differences between sexes exist, we established a fast UPLC-MS/MS method to determine mifepristone concentrations in plasma, and analyzed blood concentrations of mifepristone over time in rats and dogs of both sexes...
March 8, 2018: Journal of Pharmaceutical and Biomedical Analysis
Nikita Woodhead, Kelly M Hare, Alison Cree
The existence of sex differences in digit-length ratio (especially between the second and fourth digits, 2D:4D) is well established for humans from fetal life onwards, and has been linked with later performance. In rodents, the ratio is affected prenatally by exposure to androgens and estrogens, with some research suggesting an influence from sex of the neighbouring intrauterine fetus. However, the ubiquity and ontogenetic development of sexual dimorphism in digit ratios is not well established among wild amniotes...
March 15, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
Tarisai Chiyaka, Phillis Mushati, Bernadette Hensen, Sungai Chabata, James R Hargreaves, Sian Floyd, Isolde J Birdthistle, Frances M Cowan, Joanna R Busza
Young women (aged 15-24) who exchange sex for money or other support are among the highest risk groups for HIV acquisition, particularly in high prevalence settings. To prepare for introduction and evaluation of the DREAMS programme in Zimbabwe, which provides biomedical and social interventions to reduce adolescent girls' and young women's HIV vulnerability, we conducted a rapid needs assessment in 6 towns using a "social mapping" approach. In each site, we talked to adult sex workers and other key informants to identify locations where young women sell sex, followed by direct observation, group discussions and interviews...
2018: PloS One
Olivier Beauchet, Cyrille P Launay, Harmehr Sekhon, Jennifer Gautier, Julia Chabot, Elise J Levinoff, Gilles Allali
BACKGROUND: Assessment of changes in higher levels of gait control with aging is important to better understand age-related gait instability, with the perspective to improve the screening of individuals at risk for falls. The comparison between actual Timed Up and Go test (aTUG) and its imagined version (iTUG) is a simple clinical way to assess age-related changes in gait control. The modulations of iTUG performances by body positions and motor imagery (MI) strategies with normal aging have not been evaluated yet...
2018: PloS One
Meimei Ji, Amber Tang, Yefu Zhang, Jiaojiao Zou, Guangyu Zhou, Jing Deng, Lina Yang, Mingzhi Li, Jihua Chen, Hong Qin, Qian Lin
BACKGROUND: Pediatric overweight and obesity has become a major public health problem in China. The goal of this study is to understand overweight and obesity in preschool children in Changsha City in the context of their sleep and physical activity. These results offer feasible proposals to reduce levels of overweight and obesity among preschool children. METHODS: A total of 112 preschoolers aged three to six years old were investigated using multiple stage stratified cluster sampling and simple random sampling...
March 15, 2018: International Journal of Environmental Research and Public Health
Amy C Justice, Kirsha S Gordon, Melissa Skanderson, Eva Jennifer Edelman, Kathleen M Akgün, Cynthia L Gibert, Vincent Lo Re, David Rimland, Julie A Womack, Christina M Wyatt, Janet P Tate
BACKGROUND: HIV-positive individuals (HIV+) on antiretrovirals commonly take enough other medications to cross a threshold for polypharmacy but little is known about associated outcomes. We asked whether non-antiretroviral polypharmacy is associated with hospitalization and mortality and whether associations differ by HIV status. METHODS: Data on HIV+ and uninfected individuals in the US Veterans Affairs Healthcare System were analyzed. Eligible HIV+ were on antiretrovirals with suppressed HIV-1 RNA and uninfected individuals received at least one medication...
March 27, 2018: AIDS
Kate S Wilson, George Wanje, Linnet Masese, Jane Simoni, Juma Shafi, Lucy Adala, Julie Overbaugh, Walter Jaoko, Barbra A Richardson, R Scott McClelland
BACKGROUND: Little is known about fertility desire in HIV-positive female sex workers (FSW). Fertility desire could increase HIV transmission risk if it were associated with condomless sex or lower adherence to antiretroviral therapy (ART). METHODS: A prospective cohort study was conducted among 255 HIV-positive FSWs in Mombasa, Kenya. Using generalized estimating equations, fertility desire was evaluated as a risk factor for semen detection in vaginal secretions by prostate specific antigen (PSA) test, a biomarker of condomless sex, detectable plasma viral load (VL), and HIV transmission potential, defined as visits with positive PSA and detectable VL...
March 13, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Oyetunde Kazeem Ekeolu, Olamide Elizabeth Adebiyi
BACKGROUND: Hematological parameters are vital diagnostic tools for understanding health dynamics of humans and animals. Franquet's fruit bat (Epomops franqueti) is host to several parasites such as protozoa, bacteria, viruses and mites. Yet, studies exploring the values of its blood components with interest for research or food purposes are scarce. Thus, this study was carried out to investigate the hematological values of the adult E. franqueti. METHODS: Seventeen (nine female and eight male) apparently healthy adult E...
March 15, 2018: Journal of Basic and Clinical Physiology and Pharmacology
Brandon Jf Gheller, Phillip Joy, Daphne Lordly
PURPOSE: In Canada, dietitians serve a sex-diverse population despite the profession being predominately female (>95%). It is unknown why there are so few male dietitians. The objective of the present study was to explore the experience of the male dietitian, as a minority, in female-dominated dietetics. METHODS: Two semi-structured interviews were conducted, approximately 6 weeks apart, with Nova Scotian male dietitians. The interviews prompted participants to reflect on their experience of being a male dietitian...
March 15, 2018: Canadian Journal of Dietetic Practice and Research
Marc N Jarczok, Corina Aguilar-Raab, Julian Koenig, Michael Kaess, Jeremy C Borniger, Randy J Nelson, Martica Hall, Beate Ditzen, Julian F Thayer, Joachim E Fischer
INTRODUCTION: Successful regulation of emotional states is positively associated to mental health, while difficulties in regulating emotions are negatively associated to overall mental health and in particular associated with anxiety or depression symptoms. A key structure associated to socio-emotional regulatory processes is the central autonomic network. Activity in this structure is associated to vagal activity can be indexed noninvasively and simply by measures of peripheral cardiac autonomic modulations such as heart rate variability...
March 15, 2018: Chronobiology International
Yasuo Hagihara, Takashi Nara
OBJECTIVES: This study aimed to investigate differences in the diaphyseal cross-sectional geometry (CSG) of the metatarsal bones (MTs) between two populations with different habitual activities: the Jomon hunter-gatherers and modern Japanese people. MATERIALS AND METHODS: We evaluated the first through fifth MTs of 117 skeleton samples: 59 (33 men and 26 women) were obtained from Late and Final Jomon period archeological sites and 58 (31 men and 27 women) were from modern Japanese people...
March 15, 2018: American Journal of Physical Anthropology
Eglal E Elrayah, Siham A Balla, Haidar Abu Ahmed
Anthropometric measurements are used to assess growth of children which is affected by different biological and environmental factors. The importance of the period after the first 1000 days of life has been identified in the attempt to restore normal growth and body functions. The objectives of this study are to assess the growth and nutritional status of school children in Khartoum locality, Khartoum State, Sudan and to verify socioeconomic status and sex as factors influencing growth of children. This is a cross-sectional school-based study including 390 children, males and females, of ages between 5-12 years (60-44 months) from private and public schools...
March 15, 2018: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
Harsh H Buddhadev, Daniel L Crisafulli, David N Suprak, Jun G San Juan
Cycling is commonly prescribed for physical rehabilitation of individuals with knee osteoarthritis (OA). Despite the known therapeutic benefits, no research has examined interlimb symmetry of power output during cycling in these individuals. We investigated the effects of external workload and cadence on interlimb symmetry of crank power output in individuals with knee OA versus healthy controls. Twelve older participants with knee OA and 12 healthy sex- and age-matched controls were recruited. Participants performed 2-minute bouts of stationary cycling at four workload-cadence conditions (75 W-60 rpm, 75 W-90 rpm, 100 W-60 rpm, and 100 W-90 rpm)...
March 15, 2018: Journal of Applied Biomechanics
Sylvia E Badon, Alyson J Littman, K C Gary Chan, Michelle A Williams, Daniel A Enquobahrie
BACKGROUND: Although perinatal walking and yoga have been associated with decreased risks of pregnancy complications, associations with offspring birth size have been inconsistent. We investigated associations of prepregnancy and early pregnancy leisure-time light/moderate walking and yoga practice with birth size. METHODS: Study participants (N = 3687) reported leisure-time physical activity duration (hours per week) in the year before pregnancy and early pregnancy...
March 15, 2018: Journal of Physical Activity & Health
Thomas A Haugen, Paul A Solberg, Carl Foster, Ricardo Morán-Navarro, Felix Breitschädel, Will G Hopkins
The aim of this study was to quantify peak age and improvements over the preceding years to peak age in elite athletic contestants according to athlete performance level, sex and discipline. Individual season bests for world-ranked top 100 athletes from 2002 to 2016 (14937 athletes and 57049 individual results) were downloaded from the International Association of Athletics Federations' web site. Individual performance trends were generated by fitting a quadratic curve separately to each athlete's performance and age data using a linear modeling procedure...
March 15, 2018: International Journal of Sports Physiology and Performance
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