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https://www.readbyqxmd.com/read/28902876/postoperative-lead-migration-in-deep-brain-stimulation-surgery-incidence-risk-factors-and-clinical-impact
#1
Takashi Morishita, Justin D Hilliard, Michael S Okun, Dan Neal, Kelsey A Nestor, David Peace, Alden A Hozouri, Mark R Davidson, Francis J Bova, Justin M Sporrer, Genko Oyama, Kelly D Foote
INTRODUCTION: Deep brain stimulation (DBS) is an effective treatment for multiple movement disorders and shows substantial promise for the treatment of some neuropsychiatric and other disorders of brain neurocircuitry. Optimal neuroanatomical lead position is a critical determinant of clinical outcomes in DBS surgery. Lead migration, defined as an unintended post-operative displacement of the DBS lead, has been previously reported. Despite several reports, however, there have been no systematic investigations of this issue...
2017: PloS One
https://www.readbyqxmd.com/read/28706587/management-of-ventricular-tachycardia-storm-in-patients-with-structural-heart-disease
#2
REVIEW
Daniele Muser, Pasquale Santangeli, Jackson J Liang
Electrical storm (ES) is a medical emergency characterized by repetitive episodes of sustained ventricular arrhythmias (VAs) in a limited amount of time (at least 3 within a 24-h period) leading to repeated appropriate implantable cardioverter defibrillator therapies. The occurrence of ES represents a major turning point in the natural history of patients with structural heart disease being associated with poor short- and long-term survival particularly in those with compromised left ventricular ejection fraction (LVEF) that can develop hemodynamic decompensation and multi-organ failure...
June 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28571618/repetitive-use-of-levosimendan-in-advanced-heart-failure-need-for-stronger-evidence-in-a-field-in-dire-need-of-a-useful-therapy
#3
Gerhard Pölzl, Johann Altenberger, Loant Baholli, Paola Beltrán, Attila Borbély, Josep Comin-Colet, Juan F Delgado, Francesco Fedele, Antonella Fontana, Friedrich Fruhwald, Gregory Giamouzis, George Giannakoulas, Martín J Garcia-González, Finn Gustafsson, Kari Kaikkonen, Matti Kivikko, Jacek Kubica, Dirk von Lewinski, Ida Löfman, Gabriella Malfatto, Nicolás Manito, Martin Martínez-Sellés, Josep Masip, Bela Merkely, Fabrizio Morandi, Henning Mølgaard, Fabrizio Oliva, Emil Pantev, Zoltán Papp, Gian Piero Perna, Roman Pfister, Vito Piazza, Ramón Bover, Diego Rangel-Sousa, Alejandro Recio-Mayoral, Alexander Reinecke, Andreas Rieth, Toni Sarapohja, Gunter Schmidt, Mirko Seidel, Stefan Störk, Bojan Vrtovec, Gerhard Wikström, Patrik Yerly, Piero Pollesello
Patients in the latest stages of heart failure are severely compromised, with poor quality of life and frequent hospitalizations. Heart transplantation and left ventricular assist device implantation are viable options only for a minority, and intermittent or continuous infusions of positive inotropes may be needed as a bridge therapy or as a symptomatic approach. In these settings, levosimendan has potential advantages over conventional inotropes (catecholamines and phosphodiesterase inhibitors), such as sustained effects after initial infusion, synergy with beta-blockers, and no increase in oxygen consumption...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28437353/evaluation-of-the-modern-luque-trolley-construct-for-the-treatment-of-early-onset-scoliosis-using-a-gliding-implant-in-an-immature-animal-model
#4
Jean A Ouellet, Catherine E Ferland, Karina Klein, Guillaume Racloz, Karina Klein, Henning Richter, Thomas Steffen, Brigitte von Rechenberg
STUDY DESIGN: This was an experimental animal study. OBJECTIVE: To determine biological compatibility, stability, and growth potential of the Trolley Gliding Vehicle (TGV) used in a novel surgical technique for guided spinal growth. SUMMARY OF BACKGROUND DATA: Current treatments for early-onset scoliosis maintaining spinal growth consist of posteriorly based spinal constructs requiring repetitive lengthening. Such interventions have a high rate of complications...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28249094/effect-of-ischemic-postconditioning-during-primary-percutaneous-coronary-intervention-for-patients-with-st-segment-elevation-myocardial-infarction-a-randomized-clinical-trial
#5
Thomas Engstrøm, Henning Kelbæk, Steffen Helqvist, Dan Eik Høfsten, Lene Kløvgaard, Peter Clemmensen, Lene Holmvang, Erik Jørgensen, Frants Pedersen, Kari Saunamaki, Jan Ravkilde, Hans-Henrik Tilsted, Anton Villadsen, Jens Aarøe, Svend Eggert Jensen, Bent Raungaard, Hans E Bøtker, Christian J Terkelsen, Michael Maeng, Anne Kaltoft, Lars R Krusell, Lisette O Jensen, Karsten T Veien, Klaus Fuglsang Kofoed, Christian Torp-Pedersen, Kasper Kyhl, Lars Nepper-Christensen, Marek Treiman, Niels Vejlstrup, Kiril Ahtarovski, Jacob Lønborg, Lars Køber
Importance: Ischemic postconditioning of the heart during primary percutaneous coronary intervention (PCI) induced by repetitive interruptions of blood flow to the ischemic myocardial region immediately after reopening of the infarct-related artery may limit myocardial damage. Objective: To determine whether ischemic postconditioning can improve the clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI). Design, Setting, And Participants: In this multicenter, randomized clinical trial, patients with onset of symptoms within 12 hours, STEMI, and thrombolysis in myocardial infarction (TIMI) grade 0-1 flow in the infarct-related artery at arrival were randomized to conventional PCI or postconditioning...
May 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28216909/aneuploidy-screening-by-array-comparative-genomic-hybridization-improves-success-rates-of-in-vitro-fertilization-a-multicenter-indian-study
#6
Aditi Kotdawala, Deven Patel, Javier Herrero, Rajni Khajuria, Nalini Mahajan, Manish Banker
OBJECTIVE: To evaluate the usefulness of preimplantation genetic screening (PGS) using array comparative genomic hybridization (aCGH) in the Indian population. MATERIALS AND METHODS: This is a retrospective, multicenter study including 235 PGS cycles following intracytoplasmic sperm injection performed at six different infertility centers from September 2013 to June 2015. Patients were divided as per maternal age in several groups (<35, 35-36, 37-38, 39-40, and >40 years) and as per indication for undergoing PGS...
October 2016: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/28202072/a-pilot-randomised-controlled-trial-evaluating-mini-and-conventional-implant-retained-dentures-on-the-function-and-quality-of-life-of-patients-with-an-edentulous-mandible
#7
Sarra Jawad, Craig Barclay, William Whittaker, Martin Tickle, Tanya Walsh
BACKGROUND: Total tooth loss (edentulism) can be a debilitating condition, impacting on ability to chew, speak and interact with others. The most common treatment is with complete removable dentures, which may be successful, but in the lower jaw, bone resorption that worsens over time makes denture-wearing difficult. Two dental implants in the mandible to retain the lower denture has been advocated as the gold standard of treatment, but has not been universally provided due largely to financial constraints and also patient fear...
February 15, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28053382/a-novel-adjustable-dynamic-plate-for-treatment-of-long-bone-fractures-an-in-vitro-biomechanical-study
#8
Ahmet Karakasli, Nihat Acar, Ahmet Karaarslan, Fatih Ertem, Hasan Havitcioglu
INTRODUCTION: Locking compression plate (LCP) system was designed to provide bone stability and to enhance bone healing. However, implant failure, nonunion and instability are still frequently encountered complications. The purpose of this study was to assess and compare the biomechanical characteristics of a novel adjustable dynamic plate (ADP) with the commonly used LCP. MATERIALS AND METHODS: Twelve 4th generation composite artificial femoral bones were used...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/27771111/ziconotide-intrathecal-delivery-as-treatment-for-secondary-therapeutic-failure-of-motor-cortex-stimulation-after-6%C3%A2-years
#9
J Voirin, I Darie, D Fischer, A Simon, I Rohmer-Heitz, F Proust
INTRODUCTION: Motor cortex stimulation is a well-known treatment modality for refractory neuropathic pain. Nevertheless, some cases of therapeutic failure have been described but alternative therapies for these cases are rarely reported. CASE REPORT: The patient presented with neuropathic pain in his right arm due to a cervical syrinx which was surgically treated by a shunt in 2003 with no clinical improvement. As alternative therapy, after an evaluation by repetitive magnetic transcranial stimulation with significant benefit, motor cortex stimulation was successfully implanted in 2004...
October 2016: Neuro-Chirurgie
https://www.readbyqxmd.com/read/27755013/effectiveness-of-extracorporeal-life-support-for-patients-with-cardiogenic-shock-due-to-intractable-arrhythmic-storm
#10
Solène Le Pennec-Prigent, Erwan Flecher, Vincent Auffret, Guillaume Leurent, Jean-Claude Daubert, Christophe Leclercq, Philippe Mabo, Jean-Philippe Verhoye, Raphael P Martins
OBJECTIVES: Extracorporeal life support is used for patients with severe heart failure as a bridge to heart transplantation or recovery. We aimed at analyzing the efficacy and safety of extracorporeal life support to treat refractory arrhythmic storm responsible for cardiogenic shock in patients resistant to antiarrhythmic drugs. DESIGN: Retrospective study. SETTING: University Hospital of Rennes, France. PATIENTS: Patients with refractory arrhythmic storm admitted between January 2005 and March 2015...
March 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/27721198/mesh-expansion-as-the-cause-of-bulging-after-abdominal-wall-hernia-repair
#11
E B Deerenberg, J Verhelst, S E R Hovius, J F Lange
BACKGROUND: Recurrence is the most important complication of abdominal wall reconstruction. It is possible the repair itself is intact, but bulging or expansion of mesh causes recurrent swelling's of the abdominal wall. CASE SUMMARY: In this report, we present bulging of a polyester mesh due to central pore expansion. DISCUSSION: Repetitive stress and variations in intra-abdominal pressure can change tensile strength and stretches mesh materials...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27652126/carotid-blowout-syndrome-after-nasopharyngeal-carcinoma-radiotherapy-successful-treatment-by-internal-carotid-artery-occlusion-after-stent-implantation-failure
#12
Fei Dong, Qian Li, JianJun Wu, MinMing Zhang, GuangQiang Zhang, Bin Li, Kai Jin, Jie Min, WeiRen Liang, Ming Chao
INTRODUCTION: Carotid blowout syndrome (CBS) secondary to radiation therapy is life-threatening and requires emergency treatment. More recently, endovascular treatment has provided an effective way to control CBS-related bleeding. CASE DESCRIPTION: We present a case of CBS with a rupture of the internal carotid artery (ICA) pseudo-aneurysm after Gamma Knife radiation therapy for nasopharyngeal carcinoma (NPC). The patient was a 55-year-old man who was transferred to our hospital with severe repetitive epistaxis...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27507280/biomechanical-behavior-of-bioprosthetic-heart-valve-heterograft-tissues-characterization-simulation-and-performance
#13
REVIEW
Joao S Soares, Kristen R Feaver, Will Zhang, David Kamensky, Ankush Aggarwal, Michael S Sacks
The use of replacement heart valves continues to grow due to the increased prevalence of valvular heart disease resulting from an ageing population. Since bioprosthetic heart valves (BHVs) continue to be the preferred replacement valve, there continues to be a strong need to develop better and more reliable BHVs through and improved the general understanding of BHV failure mechanisms. The major technological hurdle for the lifespan of the BHV implant continues to be the durability of the constituent leaflet biomaterials, which if improved can lead to substantial clinical impact...
December 2016: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/27376777/alpha-plus-beta-annealed-and-aged-ti-15-mo-alloy-for-high-strength-implant-applications
#14
John A Disegi, Michael D Roach, Rod D McMillan, Brian T Shultzabarger
Management of femur fractures requires titanium alloy implants that provide a good combination of static strength and ductility plus sufficient high cycle fatigue strength to resist repetitive loading. A research program was initiated to determine whether aging treatments could increase the strength of alpha + beta Ti-15Mo while maintaining acceptable tensile ductility. A pilot heat treating study indicated the best combination of strength and ductility was obtained using an α + β annealing temperature of 705°C ± 10°C followed by an aging treatment of 482°C ± 10°C...
July 4, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/27353062/fatigue-failure-of-dental-implants-in-simulated-intraoral-media
#15
K Shemtov-Yona, D Rittel
Metallic dental implants are exposed to various intraoral environments and repetitive loads during service. Relatively few studies have systematically addressed the potential influence of the environment on the mechanical integrity of the implants, which is therefore the subject of this study. Four media (groups) were selected for room temperature testing, namely dry air, saliva substitute, same with 250ppm of fluoride, and saline solution (0.9%). Monolithic Ti-6Al-4V implants were loaded until fracture, using random spectrum loading...
September 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27237382/damage-in-total-knee-replacements-from-mechanical-overload
#16
William F Zimmerman, Mark A Miller, Richard J Cleary, Timothy H Izant, Kenneth A Mann
The mechanical loads acting across the knee joint following total knee replacements (TKR) during activities of daily living have recently been measured using instrumented TKRs. Using a series of postmortem retrieved TKR constructs we investigated whether these mechanical loads could result in damage to the implant bone interface or supporting bone in the tibia. Eighteen cemented en bloc tibial components (0 to 22 years in service) were loaded under axial compression in increments from 1 to 10 times body weight and digital image correlation was used to measure bone strain and interface micromotion during loading and unloading...
July 5, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27121484/evaluation-of-the-efficacy-and-robustness-of-a-second-generation-implantable-stimulator-in-a-patient-with-hemiplegia-during-20-years-of-functional-electrical-stimulation-of-the-common-peroneal-nerve
#17
Polona Pečlin, Janez Rozman, Janez Krajnik, Samo Ribarič
We evaluated the efficacy and robustness of a second generation implantable stimulator for correcting drop foot (DF) in a patient with left-sided hemiplegia over 20 years of functional electrical stimulation (FES) of the common peroneal nerve (CPN). Dorsal flexion and eversion of the affected foot was partially restored by FES of the superficial region of the CPN innervating mostly the tibialis anterior (TA) and partly peroneus longus (PL) and peroneus brevis (PB) muscles. The reasons for implant failure during the long-term follow-up assessment were analyzed and resolving procedures were identified...
November 2016: Artificial Organs
https://www.readbyqxmd.com/read/26866043/correction-of-the-recording-artifacts-and-detection-of-the-functional-deviations-in-ecg-by-means-of-syndrome-decoding-with-an-automatic-burst-error-correction-of-the-cyclic-codes-using-periodograms-for-determination-of-the-code-component-spectral-range
#18
Evgenie D Adamovic, Pavel L Aleksandrov, Oleg V Gradov, Leonid M Mamalyga, Maksim L Mamalyga
AIMS: This paper describes a novel approach to the analysis of electrocardiographic data based on the consideration of the repetitive P, Q, R, S, T sequences as cyclic codes. In Part I we introduce a principle similar to the syndrome decoding using the control numbers, which allows correcting the noise combinations. MATERIALS AND METHODS: We propose to apply the burst-error-correcting algorithms for automatic detection of the ECG artifacts and the functional abnormalities, including those compared to the reference model...
May 2015: Cardiometry
https://www.readbyqxmd.com/read/26678394/darbepoetin-%C3%AE-promotes-cell-proliferation-in-established-extrahepatic-colorectal-tumors-after-major-hepatectomy
#19
Sebastian Senger, Otto Kollmar, Michael D Menger, Kathrin Rupertus
BACKGROUND: The glycoprotein hormone erythropoietin and its analogue darbepoetin-α (DPO) have been shown to reduce the risk of acute liver failure after major hepatectomy. However, previous experimental studies have also shown that DPO significantly enhances neovascularization and tumor cell proliferation in established colorectal liver metastasis in hepatectomized and nonhepatectomized mice. The present study now analyzes whether DPO influences cell proliferation and migration as well as vascularization and growth of established colorectal metastasis at extrahepatic sites after major hepatectomy...
2016: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://www.readbyqxmd.com/read/26663684/application-of-tissue-engineering-to-pelvic-organ-prolapse-and-stress-urinary-incontinence
#20
REVIEW
Christopher R Chapple, Nadir I Osman, Altaf Mangera, Christopher Hillary, Sabiniano Roman, Anthony Bullock, Sheila Macneil
Synthetic or biological materials can be used for the surgical repair of pelvic organ prolapse (POP) or stress urinary incontinence (SUI). While non-degradable synthetic mesh has a low failure rate, it is prone to complications such as infection and erosion, particularly in the urological/gynecological setting when subject to chronic influences of gravity and intermittent, repetitive strain. Biological materials have lower complication rates, although allografts and xenografts have a high risk of failure and the theoretical risk of infection...
May 2015: Lower Urinary Tract Symptoms
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