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Medial nutrition therapy

Nai-Jen Chang, Yi-Ting Lin, Chih-Chan Lin, Hsueh-Chun Wang, Horng-Chaung Hsu, Ming-Long Yeh
BACKGROUND: Although various alterative models of therapy are used for cartilage repair, no definite conclusion has been reached. Glucosamine (GlcN) is widely used as a nutritional supplement. However, the clinical- evidence-based outcome of GlcN administration remains controversial. N-acetyl-D-glucosamine (GlcNAc), a derivative of GlcN, shows chondroprotective activity and mediates the activation of articular chondrocytes. Therefore, we investigated the effect of intra-articular administration of GlcNAc in rabbits' knee joints with experimental full-thickness articular cartilage (FTAC) defects...
November 18, 2015: Biomedical Engineering Online
Daniel M Balkin, Isaac Chen, Snehlata Oberoi, Jason H Pomerantz
Hecht Syndrome is an autosomal dominant distal arthrogryposis caused by mutation in the MYH8 locus characterized by trismus and pseudocamptodactyly. Hecht-associated trismus is thought to result from bilateral hyperplasia of the mandibular coronoid processes. Although several interventions to address trismus have been pursued, no consensus exists regarding optimal management. In this report, the authors present a 7-month-old male with Hecht Syndrome referred for management of trismus. By age 2, interincisal opening had progressively decreased from 12 to 5 mm despite physical therapy...
September 2015: Journal of Craniofacial Surgery
C Labruyère, V Zeller, L Lhotellier, N Desplaces, P Léonard, P Mamoudy, S Marmor
BACKGROUND: The main reasons for revision of unicompartmental knee arthroplasty (UKA) are loosening, wear, extension of osteoarthritis to another compartment, and infection. There have been no studies of the management of infected UKA, whose incidence varies from 0.2% to 1%. Our objective was to describe infection-related and mechanical outcomes of chronic UKA infection managed by one-stage conversion to total knee arthroplasty (TKA). PATIENTS AND METHODS: Consecutive patients with chronic UKA infection managed by one-stage conversion to TKA between January 2003 and December 2010 were included in a retrospective single-center study...
September 2015: Orthopaedics & Traumatology, Surgery & Research: OTSR
Elif Acar Arslan, Saniye Ekinci, Pınar Zengin Akkuş, Rahşan Göçmen, Göknur Haliloğlu
BACKGROUND: Wernicke encephalopathy is rare in children and is caused by thiamine deficiency. It is characterized by acute or subacute ataxia, altered consciousness, and ophthalmoparesis. Gastroenterological surgery, total parenteral nutrition for short bowel syndrome, and alcoholism are common risk factors for Wernicke encephalopathy. Typical magnetic resonance imaging features include selective symmetrical signal changes in the mammillary bodies, medial thalamus, tectum, periaqueductal region, cranial nerves, cerebellum, red nucleus, dentate nucleus, fornix, splenium, cerebral cortex, and putamen...
December 2014: Pediatric Neurology
Linda Hertlein, Angela Kirschenhofer, Sophie Fürst, Daniela Beer, Christine Göß, Miriam Lenhard, Klaus Friese, Alexander Burges, Peter Rittler
OBJECTIVES: An association between malnutrition and poor patient outcome has been established in various medical fields, but there is a general lack of data on the prevalence of malnutrition among gynecologic patients. Therefore an assessment of malnutrition is needed to detect malnourished patients in gynecology and initiate nutritional therapy if needed. STUDY DESIGN: Between 2011 and 2012 at our Gynecologic Department of a German University Hospital, 397 patients were evaluated regarding the risk of malnutrition and occurrence of complications during the time of hospitalization...
March 2014: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Derrick M Knapik, Joshua D Harris, Garett Pangrazzi, Michael J Griesser, Robert A Siston, Sudha Agarwal, David C Flanigan
PURPOSE: To determine whether the basic science evidence supports the use of continuous passive motion (CPM) after articular cartilage injury in the knee. METHODS: A systematic review was performed identifying and evaluating studies in animal models that focused on the basic science of CPM of the knee. Databases included in this review were PubMed, Biosis Previews, SPORTDiscus, PEDro, and EMBASE. All functional, gross anatomic, histologic, and histochemical outcomes were extracted and analyzed...
October 2013: Arthroscopy: the Journal of Arthroscopic & related Surgery
Eijin Ashikaga, Hirokazu Honda, Hiroki Suzuki, Nozomu Hosaka, Yuki Hirai, Daisuke Sanada, Mari Nakamura, Hisako Nagai, Kei Matsumoto, Noriyuki Kato, Masanori Mukai, Makoto Watanabe, Keiko Takahashi, Kanji Shishido, Tadao Akizawa
Levels of fibroblast growth factor (FGF) 23, a phosphatonin, are frequently elevated in patients with end-stage renal disease (ESRD) who are on maintenance hemodialysis (MHD). However, the role of FGF23 remains unclear because renal FGF receptor function might be impaired. The present cross-sectional study examines a cohort of patients (n = 196) on MHD who were not undergoing therapy with lipid-lowering drugs including sevelamer. Non-fasting venous blood samples were withdrawn before the hemodialysis (HD) session on the third day after the previous HD session to measure serum levels of albumin, calcium (Ca), phosphate (P), alkaline phosphatase, intact parathyroid hormone (PTH), total cholesterol (C), high-density lipoprotein (HDL)-C, low-density lipoprotein(LDL)-C, oxidative LDL-C, high-sensitivity C-reactive protein (HsCRP), interleukin-6 (IL-6), and FGF23...
June 2010: Therapeutic Apheresis and Dialysis
Stéphanie-Anne Girard, Thierno Madjou Bah, Sévan Kaloustian, Laura Lada-Moldovan, Isabelle Rondeau, Thomas A Tompkins, Roger Godbout, Guy Rousseau
Myocardial infarction (MI) stimulates the release of pro-inflammatory substances that induce apoptosis in the limbic system. Pro-inflammatory cytokines are considered as the root cause of apoptosis, although the mechanism is not fully explained and/or understood at this time. In addition, depression may induce gastrointestinal perturbations that maintain the elevated levels of pro-inflammatory cytokines. It has been shown that some specific probiotic formulations may reduce gastrointestinal problems induced by stress and the pro/anti-inflammatory cytokine ratio...
November 2009: British Journal of Nutrition
V Charles, S Boulvin, F Haven, M Gille
INTRODUCTION: We report the case of a patient with an unusual association of Wernicke encephalopathy and chronic disulfiram intoxication. CASE REPORT: A 41-year-old man presented with progressive frontal decline and akineto-rigid parkinsonism under chronic disulfiram therapy. He also developed acute confusion with ataxia, blepharospasm, and supranuclear ophthalmoplegia following a severe malnutrition due to refusal of food intake. Brain MRI revealed symmetrical and reversible hyperintense lesions on T2 and FLAIR in the posterior putaminal regions, dorso-medial thalamic and subthalamic nuclei, the periaqueducal gray matter, the cerebellar peduncles, and the pontine tegmentum...
December 2006: Revue Neurologique
P Dehail, P-A Joseph, P Faux, M Rainfray, J P Emeriau, M Barat, I Bourdel-Marchasson
BACKGROUND: In older people, the decrease in muscle mass and strength has a bad effect on functional status. Malnutrition and lack of physical activity exacerbate this phenomenon. OBJECTIVE: The main purpose of this study was to estimate isokinetic lower limb muscle strength in recovering older subjects on the basis of nutritional status. DESIGN: Twenty-eight elderly subjects hospitalized for an acute event (85.8 +/- 6 years), including 16 malnourished, were enrolled in this study when clinically stable (T0)...
September 2005: Journal of Nutrition, Health & Aging
Yoshifumi Ubara, Ryouji Takei, Jyunichi Hoshino, Tetsuo Tagami, Naoki Sawa, Masafumi Yokota, Hideyuki Katori, Fumi Takemoto, Shigeko Hara, Kenmei Takaichi
Because the kidneys in patients with autosomal dominant polycystic kidney disease (ADPKD) are usually supplied by well-developed arteries, the authors attempted renal contraction therapy in such patients with renal transcatheter arterial embolization (TAE) using intravascular coils. In most patients with marked nephromegaly, renal TAE was effective. However, in patients with marked hepatomegaly without significant nephromegaly, renal TAE was not effective, and hepatic treatment was always required. In June 2001, the authors obtained approval for a new treatment,"TAE for enlarged polycystic liver," from an ethics committee discussing new treatment at their hospital...
April 2004: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
R Gaulke
INTRODUCTION: Medial and pertrochanteric fractures of the femoral neck occur commonly in patients with bone weakness due to osteoporosis or osteomalacia. Combined bilateral hip injury is much rarer. PATIENTS AND METHODS: The case of a Turkish woman with bilateral fractures of the femoral neck due to secondary hyperparathyroidism caused by nutritional vitamin-D 3 deficiency is described and compared to 80 cases of bilateral hip fractures mentioned in English and German literature...
May 2002: Zeitschrift Für Orthopädie und Ihre Grenzgebiete
J Harrison, J McKiernan, J M Neuberger
In a prospective study, we have examined the effect of nutritional status, using anthropometric measurements, on outcome in 102 consecutive adult patients undergoing elective orthotopic liver transplantation. Mid-arm muscle circumference was calculated from these two measurements. Patient outcome variables were time spent in the intensive therapy unit, total time in hospital, infective complications and mortality within 6 months. Graft outcome variables were early graft function, peak aspartate transaminase, alkaline phosphatase, bilirubin and prothrombin time...
1997: Transplant International: Official Journal of the European Society for Organ Transplantation
M Ito, Y Asanuma, S Shibata, T Saitoh, K Koyama, J Watarai, H Masuda
For the treatment of pancreatic head cancer, pancreatoduodenectomy is followed by the intraoperative radiation therapy (IORT). The present dose adopted ranged 20 to 30 Gy, however the dose is believed to be insufficient for local control of adenocarcinoma cells. In this study, high dose IORT was performed using rabbit, so histological and nutritional changes were evaluated. Rabbits were divided in three groups; 30 Gy, 50 Gy, 80 Gy. The radiation was performed with electrons focusing base of cranial mesenteric artery (SMA in human)...
May 1993: Nihon Geka Gakkai Zasshi
J L Netterville, F J Civantos
Damage to any one of these nerves results in sufficient morbidity to warrant therapy; however, most patients will compensate for isolated loss of function. It is with multiple nerve injuries, as often seen in glomus surgery with the resection of cranial nerves IX, X, and XII that the full efforts of the rehabilitation team are called on. After vocal cord medialization and palatal adhesion, younger healthier patients will eventually resume adequate oral intake. However, the time it requires to return to a reasonably enjoyable diet often extends up to 1 year postoperatively...
November 1993: Laryngoscope
J W Ark, R H Gelberman, S O Abrahamsson, J G Seiler, D Amiel
In order to investigate fibroblast survival and proliferation in autogenous flexor tendon grafts, hindlimb intrasynovial and extrasynovial donor tendons were placed within the synovial sheaths of the medial and lateral forepaw digits of 21 dogs (42 tendons) and treated with controlled early passive motion. Intravital histologic evaluations with confocal microscopy and biochemical determinations of total DNA content and DNA synthesis were carried out at 10 days, 3 weeks, and 6 weeks. Intravital staining of the extrasynovial tendon grafts demonstrated variable degrees of cellular necrosis at the earliest intervals followed by cellular repopulation with fibroblasts and neovascularization from surface vessels...
March 1994: Journal of Hand Surgery
Y M Vissing, J C Petersen
For members of the CCS, laetrile use occurs in a self-help social context where users derive substantial social and emotional support from fellow members. We are convinced that much of the appeal of laetrile results from this social context in which it is frequently used. The CCS and the extensive network of similar organizations are fulfilling unmet needs in cancer patients and those fearful of cancer. Until conventional cancer therapy deals more successfully with the social and psychological needs of cancer patients, promoters of laetrile will till fertile ground...
November 1981: CA: a Cancer Journal for Clinicians
J R Wells, M A Jaindl, W H Gernon
The relative safety of silicone rubber catheters allows use of the deep brachial vein for long-term central venous access when other vascular access sites are unavailable or undesirable. After local infiltration, a small incision is made across the medial edge of the brachial biceps and the vein is isolated from the artery and median nerve. An introducer is used to aid in insertion of the catheter. Catheter position is checked with a postoperative radiograph of the chest. Sixty of our patients have had catheters in place from 14 to 200 days, with few complications...
December 1986: Otolaryngology—Head and Neck Surgery
D C Berridge, B R Hopkinson, G S Makin
Simultaneous readings of transcutaneous partial pressure of oxygen (Ptc,O2) were obtained from the left anterior chest wall, from 10 cm distal to the medial aspect of the knee joint, and from the first dorsal webspace in 16 patients with acute peripheral arterial ischaemia of the leg. Oxygen was administered at concentrations of 24, 40, 60 and 100 per cent. Mean (s.d.) initial chest Ptc,O2 (53(17)mmHg) was significantly higher than that of the medial lower limb site (37(17)mmHg). After inhalation of 24 per cent oxygen, a statistically significant (P less than 0...
October 1989: British Journal of Surgery
L Bentur, C Cullinane, P Wilson, M Greenberg, H O'Brodovich, M M Silver
Fatal pulmonary hypertension developed in an infant during the 7-month period in which he received, via a central venous catheter, combination chemotherapy for stage IV neuroblastoma as well as intermittent parenteral feeding. In a lung biopsy and at autopsy, small pulmonary arteries showed diffuse medial hypertrophy and peripheral muscularization, very extensive concentric intimal fibrosis, and focal eccentric fibrosis evolving from organizing thrombi. Pulmonary veins were normal. Hypothetically, chemotherapeutic drug therapy (possibly potentiated either by the parenteral nutrition or simply by the vehicular fluids causing volume loading of the pulmonary circulation) could cause occlusive pulmonary arterial disease by several mechanisms, but the association has not been described previously, although use of such drugs has been reported with pulmonary veno-occlusive disease...
December 1991: Human Pathology
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