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https://www.readbyqxmd.com/read/29166705/comprehensive-analysis-of-nine-monoamines-and-metabolites-in-small-amounts-of-peripheral-murine-c57bl-6j-tissues
#1
Joachim Nagler, Sonja C Schriever, Meri De Angelis, Paul T Pfluger, Karl-Werner Schramm
Monoamines, acting as hormones and neurotransmitters, play a critical role in multiple physiological processes ranging from cognitive function and mood to sympathetic nervous system activity, fight-or-flight response, or glucose homeostasis. In addition to brain and blood, monoamines are abundant in several tissues, and dysfunction in their synthesis or signaling is associated with various pathological conditions. It was our goal to develop a method to detect these compounds in peripheral murine tissues. In this study, we employed a high performance liquid chromatography method using electrochemical detection that allows not only detecting the catecholamines but a detailed analysis of nine monoamines and metabolites in murine tissues...
November 22, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29165908/association-between-adolescents-consumption-of-total-and-different-types-of-sugar-sweetened-beverages-with-oral-health-impacts-and-weight-status
#2
Louise L Hardy, Jane Bell, Adrian Bauman, Seema Mihrshahi
OBJECTIVE: To examine the associations between adolescents' intake of sugar-sweetened beverages (SSBs) with oral health impacts (OHI) and weight status. METHODS: Cross-sectional health survey with anthropometry and self-report OHI (toothache and avoiding some foods because of oral problems) and SSB intake (fruit juice, flavoured water, soft, diet, sports and energy drinks) collected in 2015. RESULTS: A total of 3,671 adolescents participated (50% girls; mean age 13...
November 22, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29165107/description-of-the-healthy-eating-indices-based-diet-quality-in-turkish-adults-a-cross-sectional-study
#3
Eda Koksal, Merve Seyda Karacil Ermumcu, Hande Mortas
OBJECTIVES: This study aims to describe the dietary status of Turkish adults using two different versions of the Healthy Eating Index (HEI). METHODS: In this cross sectional study, 494 healthy participants (311 females) with randomly selected and living in Ankara were included between September 2013 and March 2014. A questionnaire was completed and anthropometric measurements (weight and height) were performed. The 24-h dietary recall of individuals was collected...
March 20, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29164831/udenafil-a-phosphodiesterase-5-inhibitor-reduces-body-weight-in-high-fat-fed-mice
#4
Seong Yul Ryu, Yoon Jung Choi, So Young Park, Jong Yeon Kim, Yong Dae Kim, Yong Woon Kim
PURPOSE: High-fat (HF) feeding induces hypothalamic leptin resistance via the activation of toll-like receptor 4 (TLR4). TLR4 deficiency confers resistance to diet-induced obesity. Udenafil, an anti-impotence drug, inhibits TLR4 in airway epithelial cells in vitro. In this study, we evaluated whether udenafil suppressed the hypothalamic expression of TLR4 and reduced body weight. MATERIALS AND METHODS: The hypothalamic expression of TLR4, phosphodiesterase 5 (PDE5), nuclear factor-κB (NF-κB), and myeloid differentiation primary response gene 88 (Myd88) was analyzed by real-time polymerase chain reaction after treating mice for 2 days with udenafil (0, 12, 120, or 600 μg/d)...
November 16, 2017: World Journal of Men's Health
https://www.readbyqxmd.com/read/29164567/role-of-mll3-in-regulating-cardiac-stem-cells-following-cardiac-cachexia
#5
J-X Zhao, H-X Zhang, B Li, Q-X Fan, S-Z Xue, M Zhang, C-Q Ke
OBJECTIVE: Cardiac cachexia is a form of serious illness that results with terminal stage of heart failure. It is associated with unreasonable weight loss and muscle loss with poor prognosis. Cardiac stem cells play a major role in repairing, damaged cardiac tissue and they are regulated by different mechanisms. In the present study, we investigated the role of MLL3 in regulating cardiac stem cells following cardiac cachexia. MATERIALS AND METHODS: To effectively study the cardiac cachexia, we established a Dahl rat model that produces symptoms similar to cachexia...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29164129/a-commercially-available-portion-controlled-diet-program-is-more-effective-for-weight-loss-than-a-self-directed-diet-results-from-a-randomized-clinical-trial
#6
Chad M Cook, Courtney N McCormick, Mandi Knowles, Valerie N Kaden
Objective: To examine changes in weight and related outcomes in response to a commercial weight loss program compared to a self-directed diet in adults with overweight or obesity. Design: Participants were randomly assigned [stratified by body mass index (BMI) and age] to a commercial weight loss program (n = 38) or to a self-directed Dietary Approaches to Stop Hypertension (DASH) diet (n = 40) for a 16-week period. Daily energy intake goals were 1,500 kcal/d for men and 1,200 kcal/d for women, except for the first week of the commercial program (1,000 kcal/d)...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29163369/preconception-prebiotic-and-sitagliptin-treatment-in-obese-rats-affects-pregnancy-outcomes-and-offspring-microbiota-adiposity-and-glycemia
#7
Carol A Dennison, Amanda J Eslinger, Raylene A Reimer
Maternal obesity is associated with increased risk of pregnancy complications and greater risk of obesity in offspring, but studies designed to examine preconception weight loss are limited. The objective of this study was to determine if a combined dietary [oligofructose (OFS)] and pharmacological (sitagliptin) preconception intervention could mitigate poor pregnancy outcomes associated with maternal obesity and improve offspring metabolic health and gut microbiota composition. Diet-induced obese female Sprague-Dawley rats were randomized to one of four intervention groups for 8 weeks: (1) Obese-Control (consumed control diet during intervention); (2) Obese-OFS (10% OFS diet); (3) Obese-S (sitagliptin drug); (4) Obese-OFS + S (combination treatment)...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29163194/on-the-metabolism-of-exogenous-ketones-in-humans
#8
Brianna J Stubbs, Pete J Cox, Rhys D Evans, Peter Santer, Jack J Miller, Olivia K Faull, Snapper Magor-Elliott, Satoshi Hiyama, Matthew Stirling, Kieran Clarke
Background and aims: Currently there is considerable interest in ketone metabolism owing to recently reported benefits of ketosis for human health. Traditionally, ketosis has been achieved by following a high-fat, low-carbohydrate "ketogenic" diet, but adherence to such diets can be difficult. An alternative way to increase blood D-β-hydroxybutyrate (D-βHB) concentrations is ketone drinks, but the metabolic effects of exogenous ketones are relatively unknown. Here, healthy human volunteers took part in three randomized metabolic studies of drinks containing a ketone ester (KE); (R)-3-hydroxybutyl (R)-3-hydroxybutyrate, or ketone salts (KS); sodium plus potassium βHB...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29162611/hdl-subspecies-defined-by-presence-of-apolipoprotein-c-iii-and-incident-coronary-heart-disease-in-four-cohorts
#9
Majken K Jensen, Sarah A Aroner, Kenneth J Mukamal, Jeremy D Furtado, Wendy S Post, Michael Y Tsai, Anne Tjønneland, Joseph F Polak, Eric B Rimm, Kim Overvad, Robyn L McClelland, Frank M Sacks
Background -The causal role of high density lipoprotein (HDL) cholesterol in cardioprotection has been questioned by genetic and randomized studies. Novel measures that relate to HDL function may contribute new information to prediction of cardiovascular risk. Apolipoprotein C-III (apoC-III) is a key regulator of lipoprotein metabolism. We investigated whether subspecies of HDL defined by apoC-III are associated with coronary heart disease (CHD). Methods -We used immuno-affinity chromatography to measure the apoA-I concentrations of HDL that contains and lacks apoC-III in two prospective studies of adults free of CHD...
November 21, 2017: Circulation
https://www.readbyqxmd.com/read/29162585/diet-behavior-change-techniques-in-type-2-diabetes-a-systematic-review-and-meta-analysis
#10
REVIEW
Kevin A Cradock, Gearóid ÓLaighin, Francis M Finucane, Rhyann McKay, Leo R Quinlan, Kathleen A Martin Ginis, Heather L Gainforth
OBJECTIVE: Dietary behavior is closely connected to type 2 diabetes. The purpose of this meta-analysis was to identify behavior change techniques (BCTs) and specific components of dietary interventions for patients with type 2 diabetes associated with changes in HbA1c and body weight. RESEARCH DESIGN AND METHODS: The Cochrane Library, CINAHL, Embase, PubMed, PsycINFO, and Scopus databases were searched. Reports of randomized controlled trials published during 1975-2017 that focused on changing dietary behavior were selected, and methodological rigor, use of BCTs, and fidelity and intervention features were evaluated...
December 2017: Diabetes Care
https://www.readbyqxmd.com/read/29162544/immunostimulation-and-yellow-head-virus-yhv-disease-resistance-induced-by-a-lignin-based-pulping-by-product-in-black-tiger-shrimp-penaeus-monodon-linn
#11
Prapansak Srisapoome, Kaoru Hamano, Isao Tsutsui, Kenji Iiyama
Yellow head virus (YHV) is classified as one of the most serious pathogens causing a harmful disease in many penaeids, especially black tiger shrimp (Penaeus monodon), with high economic loss. To determine a potent and practical prophylactic strategy for controlling this disease, the toxicity of the by-product kraft lignin and its ability to control severe YHV infection were investigated in juvenile black tiger shrimp (15.9 ± 1.2 g body weight). The median lethal dosage at 96 h (96-hrs LD50) of lignin in shrimp was 297 mg/L...
November 18, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29162514/increased-sugar-intake-as-a-form-of-compensatory-hyperphagia-in-patients-with-type-2-diabetes-under-dapagliflozin-treatment
#12
Ichiro Horie, Norio Abiru, Ryoko Hongo, Takeshi Nakamura, Ayako Ito, Ai Haraguchi, Shoko Natsuda, Ikuko Sagara, Takao Ando, Atsushi Kawakami
AIMS: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) cause substantially less weight loss than would be expected based on their caloric deficits, probably due to enhanced appetite regulation known as "compensatory hyperphagia," which occurs to offset the negative energy balance caused by increased glycosuria. We examined whether any specific nutrients contributed to the compensatory hyperphagia in diabetic patients taking SGLT2i. METHODS: Sixteen patients with type 2 diabetes were newly administered dapagliflozin 5 mg daily as the experimental SGLT2i group...
November 18, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29161056/de-novo-food-allergy-in-pediatric-liver-transplantation-recipients
#13
Ratchaneewan Sinitkul, Wiparat Manuyakorn, Wasu Kamchaisatian, Soamarat Vilaiyuk, Suwat Benjaponpitak, Chatmanee Lertudompholwanit, Suporn Treepongkaruna
BACKGROUND: Food allergy (FA) prevalence is increasing in pediatric liver transplantation (LT). However, the clinical course is still limited. OBJECTIVE: This retrospective cohort study aimed to identify the prevalence, risk factors, and the natural history of de novo FA in children post LT. METHODS: Medical records of pediatric LT recipients from Jan 2001 - Dec 2014 were reviewed. De novo FA was diagnosed by symptoms after exposure to culprit food occurring after LT, and improvement after diet elimination...
November 22, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/29160184/awareness-use-and-information-sources-of-folic-acid-supplementation-to-prevent-neural-tube-defects-in-pregnant-japanese-women
#14
Shumi Yamamoto, Yoshinao Wada
OBJECTIVE: Folic acid supplementation and folate-rich diets are recommended for women of childbearing age worldwide to prevent congenital anomalies. We aimed to determine the current status of folic acid supplementation among pregnant Japanese women and identify means to increase the intake of these supplements. DESIGN: Cross-sectional study. SUBJECTS: A total of 1862 pregnant women who consulted the perinatal centre from September 2014 to December 2015 completed a questionnaire concerning knowledge about folic acid, sources of information and the use of folic acid supplements...
November 21, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29160021/sleep-timing-is-associated-with-diet-and-physical-activity-levels-in-9-11-year-old-children-from-dunedin-new-zealand-the-pedals-study
#15
Harriet A L Harrex, Sheila A Skeaff, Katherine E Black, Brittany K Davison, Jillian J Haszard, Kim Meredith-Jones, Robin Quigg, Pouya Saeedi, Lee Stoner, Jyh E Wong, Paula M L Skidmore
It is well documented that short sleep duration is associated with excess body weight and poor food intake in children. It has been suggested that sleep timing behaviour may also be an important predictor of weight and other related behaviours, independent of sleep duration; however, there is a lack of research investigating these relationships. The present study investigated sleep timing in association with diet and physical activity levels in 439 children aged 9-11 years old from New Zealand. Sleep and physical activity data were collected using accelerometry, and food choice using a short food-frequency questionnaire...
November 20, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/29159485/beriberi-outbreak-among-unauthorised-immigrants-in-a-detention-camp-in-malaysia
#16
Sunita Abdul Rahman, Mohammad Saffree Jeffree, Fadzilah Kamaludin, Intan Azura Din, Mahanim Yusof, Kamruddin Ahmed
In February 2012, a district health authority received three inmates with bilateral leg swelling and difficulty in breathing from a detention camp for unauthorized immigrants. A case control study was conducted. Fasting blood samples of case and control groups were collected according to instructions of the laboratory for determining thiamine level, and their 1 week dietary intake was analyzed. 9% (21/226) of inmates had bilateral leg swelling, and 75% (6/8) of them had low thiamine level (< 66 mmol/L)...
November 20, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29158919/antioxidant-and-antiradical-properties-of-selected-flavonoids-and-phenolic-compounds
#17
Zübeyir Huyut, Şükrü Beydemir, İlhami Gülçin
Phenolic compounds and flavonoids are known by their antioxidant properties and one of the most important sources for humans is the diet. Due to the harmful effects of synthetic antioxidants such as BHA and BHT, natural novel antioxidants have become the focus of attention for protecting foods and beverages and reducing oxidative stress in vivo. In the current study, we investigated the total antioxidant, metal chelating, Fe(3+) and Cu(2+) reduction, and free radical scavenging activities of some phenolic and flavonoid compounds including malvin, oenin, ID-8, silychristin, callistephin, pelargonin, 3,4-dihydroxy-5-methoxybenzoic acid, 2,4,6-trihydroxybenzaldehyde, and arachidonoyl dopamine...
2017: Biochemistry Research International
https://www.readbyqxmd.com/read/29158896/factors-associated-with-minimal-meal-frequency-and-dietary-diversity-practices-among-infants-and-young-children-in-the-predominantly-agrarian-society-of-bale-zone-southeast-ethiopia-a-community-based-cross-sectional-study
#18
Mekonnen Tegegne, Semere Sileshi, Tomas Benti, Mulusew Teshome, Haile Woldie
Background: Poor infant and young child feeding (IYCF) practices in the first 2 years of age are among major causes of childhood malnutrition, in developing countries including Ethiopia. It results in irreversible outcomes of stunting, poor cognitive development, and significantly increases risks of many chronic and infectious diseases. This study was intended to assess factors associated with minimum meal frequency and minimum dietary diversity practice among children aged 6-23 months in the predominantly agrarian society of Bale zone, Southeast Ethiopia...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29158657/academic-community-partnership-development-to-enhance-program-outcomes-in-underserved-communities-a-case-study
#19
Meg Skizim, Nick Harris, Claudia Leonardi, Richard Scribner
Purpose: A community-academic partnership was developed to assess community needs and restructure a variety of community-based programs that provide services to underserved communities in New Orleans, Louisiana. Methods: The community and academic partners utilized five phases to assess community needs and restructure programs: 1) meetings; 2) narrowing the scope of community programs; 3) data collection and analysis; 4) emphasizing target programs; and 5) improving sustainability through grant submissions and grant development training...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/29157320/comparison-of-high-and-low-trans-fatty-acid-consumers-analyses-of-uk-national-diet-and-nutrition-surveys-before-and-after-product-reformulation
#20
Jayne Hutchinson, Holly L Rippin, Jo Jewell, Joao J Breda, Janet E Cade
OBJECTIVE: The WHO encourages the virtual elimination of artificial trans-fatty acids (TFA), which increase CHD risk. Our UK analysis explores whether voluntary reformulation results in differential TFA intakes among socio-economic groups by determining characteristics of high TFA consumers before and after product reformulation. DESIGN: Food intake was collected by 7d weighed records pre-reformulation and 4d diaries post-reformulation. Sociodemographic characteristics of TFA consumers above the WHO limit, and of the top 10 % of TFA consumers as a percentage food energy, were compared with those of lower TFA consumers...
November 21, 2017: Public Health Nutrition
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