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https://www.readbyqxmd.com/read/29772222/outcomes-of-laser-in-situ-keratomileusis-and-photorefractive-keratectomy-in-patients-taking-isotretinoin
#1
Julio Ortega-Usobiaga, Fernando Llovet-Osuna, Mohammad Reza Djodeyre, Rafael Bilbao-Calabuig, Félix González-López, Andrea Llovet-Rausell, Vasyl Druchkiv
PURPOSE: To determine the functional outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in patients taking isotretinoin, which is contraindicated for these procedures. DESIGN: Multicentre, retrospective, interventional case series METHODS: All patients taking isotretinoin who underwent LASIK or PRK from January 2003 to September 2017 were included (group 1). Patients were compared with those undergoing LASIK or PRK who had taken isotretinoin previously but not in the previous 6 months (group 2)...
May 14, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29771728/long-term-prognostic-factors-for-visual-improvement-after-epiretinal-membrane-removal
#2
Sohee Jeon, Byungju Jung, Won Ki Lee
PURPOSE: To identify prognostic factors that may predict the amount of long-term visual improvement after idiopathic epiretinal membrane removal. METHODS: A retrospective study of 114 patients who underwent epiretinal membrane removal was performed. The central foveal thickness, inner retinal layer thickness, inner retinal irregularity index, length of the cone outer segment tip line defect, and length of the ellipsoid zone defect were measured. The optical coherence tomography parameters that were associated with the amount of visual improvement were determined at 24 months postoperatively...
May 14, 2018: Retina
https://www.readbyqxmd.com/read/29765198/management-of-post-lasik-dry-eye-a-multicenter-randomized-comparison-of-a-new-multi-ingredient-artificial-tear-to-carboxymethylcellulose
#3
Avi Wallerstein, W Bruce Jackson, Jeffrey Chambers, Amir M Moezzi, Hugh Lin, Peter A Simmons
Purpose: To compare the efficacy and safety of a preservative-free, multi-ingredient formulation of carboxymethylcellulose 0.5%, hyaluronic acid 0.1%, and organic osmolytes (CMC-HA), to preservative-free carboxymethylcellulose 0.5% (CMC) in the management of postoperative signs and symptoms of dry eye following laser-assisted in situ keratomileusis (LASIK). Methods: This was a double-masked, randomized, parallel-group study conducted in 14 clinical centers in Canada and Australia...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29760570/plasma-rich-in-growth-factors-eye-drops-to-treat-secondary-ocular-surface-disorders-in-patients-with-glaucoma
#4
Ronald M Sánchez-Avila, Jesus Merayo-Lloves, Maria Laura Fernández, Luis Alberto Rodríguez-Gutiérrez, Pedro Pablo Rodríguez-Calvo, Andres Fernández-Vega Cueto, Francisco Muruzabal, Gorka Orive, Eduardo Anitua
Purpose: To evaluate the efficacy and safety of plasma rich in growth factors (PRGF) eye drops in patients with glaucoma with secondary ocular surface disorders (OSDs) due to surgeries and topical hypotensive drugs use. Materials and methods: A retrospective case-series study design was used including six patients (eight eyes) diagnosed with glaucoma who received surgical (nonpenetrating deep sclerectomy and/or trabeculectomy) and medical treatments (hypotensive eye drops) to control intraocular pressure (IOP) and who developed secondary OSDs, unresponsive to conventional treatments...
2018: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29755819/vitreoretinal-interface-characteristics-in-eyes-with-idiopathic-macular-holes-qualitative-and-quantitative-analysis
#5
Arzu Seyhan Karatepe, Jale Menteş, E Tansu Erakgün, Filiz Afrashi, Serhad Nalçacı, Cezmi Akkın, Yeşim Ateş
Objectives: To determine the qualitative and quantitative vitreoretinal interface characteristics with spectral domain optical coherence tomography (SD-OCT) in eyes with macular hole (MH) and investigate their relation with best corrected visual acuity (BCVA) and MH duration. Materials and Methods: Sixty-one eyes of 46 consecutive patients diagnosed with idiopathic MH were included in the study. The mean age of the patients was 66.7±7.5 (51-79) years. Complete ophthalmologic examination and SD-OCT examination were performed in all eyes and MH stages were determined according to SD-OCT findings...
April 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29752057/outcomes-after-transcatheter-aortic-valve-replacement-a-propensity-matched-retrospective-cohort-study
#6
Ethan Y Brovman, Christine Kuo, Robert W Lekowski, Richard D Urman
OBJECTIVES: To examine patient acuity and perioperative outcomes in a contemporary cohort of patients undergoing either transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR). DESIGN: A retrospective propensity-matched cohort study with univariable logistic regression to assess postoperative outcomes. SETTING: Hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program...
April 10, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29748081/day-of-week-site-of-service-and-patient-complexity-differences-in-venous-ultrasound-interpreted-by-radiologists-versus-nonradiologists
#7
Anand M Prabhakar, Ravi V Gottumukkala, Wenyi Wang, Danny R Hughes, Richard Duszak
OBJECTIVE: Nationally, nonradiologists interpret an increasing proportion of lower extremity venous duplex ultrasound (LEVDU) examinations. We aimed to study day of week, site of service, and patient complexity differences in LEVDU services interpreted by radiologists versus nonradiologists. MATERIALS AND METHODS: Using carrier claims files for a 5% national sample of Medicare beneficiaries from 2012 to 2015, we retrospectively classified all LEVDU examinations by physician specialty (radiologist versus nonradiologist), day of week (weekday versus weekend), site of service, and patient Charlson Comorbidity Index (CCI) scores...
May 7, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29747934/predictors-of-critical-care-and-mortality-in-bronchiolitis-after-emergency-department-discharge
#8
Suzanne Schuh, Jeffrey C Kwong, Laura Holder, Erin Graves, Erin M Macdonald, Yaron Finkelstein
OBJECTIVES: To identify the epidemiologic predictors and stratify the risk of critical care unit (CCU) admission or death in bronchiolitis following emergency department discharge. This information has not yet been explored. STUDY DESIGN: A population-based cohort study using Ontario-wide demographic and healthcare databases linked at the individual level. We assessed all infants with bronchiolitis discharged home from all emergency departments in Ontario, Canada, 2003-2014...
April 24, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29735302/a-physician-led-initiative-to-improve-clinical-documentation-results-in-improved-health-care-documentation-case-mix-index-and-increased-contribution-margin
#9
Francesco A Aiello, Dejah R Judelson, Jonathan M Durgin, Danielle R Doucet, Jessica P Simons, Dawn M Durocher, Julie M Flahive, Andres Schanzer
INTRODUCTION: Clinical documentation is the key determinant of inpatient acuity of illness and payer reimbursement. Every inpatient hospitalization is placed into a diagnosis related group with a relative value based on documented procedures, conditions, comorbidities and complications. The Case Mix Index (CMI) is an average of these diagnosis related groups and directly impacts physician profiling, medical center profiling, reimbursement, and quality reporting. We hypothesize that a focused, physician-led initiative to improve clinical documentation of vascular surgery inpatients results in increased CMI and contribution margin...
May 4, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29726596/cost-implications-of-intraprocedural-thrombotic-events-and-bleeding-in-percutaneous-coronary-intervention-results-from-the-champion-phoenix-economics-study
#10
Hector Tamez, Philip Généreux, Robert W Yeh, Amit P Amin, Weihong Fan, Harvey D White, Ajay J Kirtane, Gregg W Stone, C Michael Gibson, Robert A Harrington, Deepak L Bhatt, Duane S Pinto
BACKGROUND: Despite improvements in percutaneous coronary intervention (PCI), intraprocedural thrombotic events (IPTE) and bleeding complications occur and are prognostically important. These have not been included in prior economic studies. METHODS: PHOENIX ECONOMICS was a substudy of the CHAMPION PHOENIX trial, evaluating cangrelor during PCI. Hospital bills were reviewed from 1,171 patients enrolled at 22 of 63 US sites. Costs were estimated using standard methods including resource-based accounting, hospital billing data, and the Medicare fee schedule...
May 4, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29716788/aquaporin-4-and-myelin-oligodendrocyte-glycoprotein-autoantibody-status-predict-outcome-of-recurrent-optic-neuritis
#11
Jiraporn Jitprapaikulsan, John J Chen, Eoin P Flanagan, W Oliver Tobin, Jim P Fryer, Brian G Weinshenker, Andrew McKeon, Vanda A Lennon, Jacqueline A Leavitt, Jan-Mendelt Tillema, Claudia Lucchinetti, B Mark Keegan, Orhun Kantarci, Cheryl Khanna, Sarah M Jenkins, Grant M Spears, Jessica Sagan, Sean J Pittock
PURPOSE: To determine the aquaporin-4 and myelin oligodendrocyte glycoprotein (MOG) immunoglobulin G (IgG) serostatus and visual outcomes in patients with recurrent optic neuritis (rON) initially seeking treatment. DESIGN: Cross-sectional cohort study. PARTICIPANTS: The study identified patients by searching the Mayo Clinic computerized central diagnostic index (January 2000-March 2017). The 246 eligible patients fulfilled the following criteria: (1) initially seeking treatment for at least 2 consecutive episodes of optic neuritis (ON) and (2) serum available for testing...
April 28, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29715365/evaluation-of-automatically-quantified-foveal-avascular-zone-metrics-for-diagnosis-of-diabetic-retinopathy-using-optical-coherence-tomography-angiography
#12
Yansha Lu, Joseph M Simonett, Jie Wang, Miao Zhang, Thomas Hwang, Ahmed M Hagag, David Huang, Dengwang Li, Yali Jia
Purpose: To describe an automated algorithm to quantify the foveal avascular zone (FAZ), using optical coherence tomography angiography (OCTA), and to compare its performance for diagnosis of diabetic retinopathy (DR) and association with best-corrected visual acuity (BCVA) to that of extrafoveal avascular area (EAA). Methods: We obtained 3 × 3-mm macular OCTA scans in diabetic patients with various levels of DR and healthy controls. An algorithm based on a generalized gradient vector flow (GGVF) snake model detected the FAZ, and metrics assessing FAZ size and irregularity were calculated...
May 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29713817/23g-pars-plana-vitrectomy-for-vitreal-floaters-prospective-assessment-of-subjective-self-reported-visual-impairment-and-surgery-related-risks-during-the-course-of-treatment
#13
Ursula Hahn, Frank Krummenauer, Klaus Ludwig
PURPOSE: Quantifying the subjective impairment due to floaters based on an indication-specific questionnaire and setting its change between prior to and 3/12 months after elective vitrectomy in relation to surgical risks. METHODS: Single-arm longitudinal observational multicenter study. Sixty-four floater patients underwent 23G pars plana vitrectomy; simultaneous phacoemulsification was excluded. An overall self-rated impairment index (SRI) and sub-indices SRI were calculated on the basis of a modified Visual Quality of Life questionnaire (VQoL), which addresses general vision, glare, near-sight problems and mobility of floaters...
April 30, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29709765/pointing-perception-is-precise
#14
S M Cooney, N Brady, A McKinney
The spontaneity and ease with which we point understates the gesture's significance to understanding cognition. Onset of pointing in infancy predicts early word acquisition and signals a capacity for shared intentionality. Yet, notwithstanding its importance, there is little research on the perception of pointing and its referents. Here we show that perceptual acuity for discerning where another person is pointing is remarkably accurate. Thresholds, as low as 0.5° of visual angle across an interpersonal distance of ∼2 m, are modulated by the referent's location in space and the hand used to point and remain constant when the pointer's eyes are occluded from view and when 'embodiment' cues are enhanced or minimized...
April 27, 2018: Cognition
https://www.readbyqxmd.com/read/29702000/the-effect-of-intravenous-insulin-apheresis-and-oral-lipid-lowering-agents-on-non-fasting-hypertriglyceridemia-and-associated-pancreatitis
#15
Daniela Frankova, Kristin Melissa Olson, Brian Joseph Whyms, Maria A Guevara Hernandez, Jan Franko
BACKGROUND: There is evidence that increasing severity of hypertriglyceridemia increases the risk of acute pancreatitis. There is a debate about superiority of treatment methods and previous works have specifically called for direct comparison between IV insulin and apheresis techniques. OBJECTIVES: Identify patient characteristics predictive of lipid-lowering therapy selection in a large community hospital for treatment of hypertriglyceridemia; evaluate for a concentration-dependent relationship between hypertriglyceridemia severity and risk of acute pancreatitis; assess for differences in clinical outcomes between patients treated with IV insulin versus apheresis...
April 27, 2018: Postgraduate Medicine
https://www.readbyqxmd.com/read/29697806/decreasing-triage-time-effects-of-implementing-a-step-wise-esi-algorithm-in-an-ehr
#16
Stephen Villa, Ellen J Weber, Steven Polevoi, Christopher Fee, Andrew Maruoka, Tina Quon
Objectives: To determine if adapting a widely-used triage scale into a computerized algorithm in an electronic health record (EHR) shortens emergency department (ED) triage time. Design: Before-and-after quasi-experimental study. Setting: Urban, tertiary care hospital ED. Participants: Consecutive adult patient visits between July 2011 and June 2013. Intervention: A step-wise algorithm, based on the Emergency Severity Index (ESI-5) was programmed into the triage module of a commercial EHR...
April 25, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29689764/a-speed-based-approach-to-vestibular-rehabilitation-for-peripheral-vestibular-hypofunction-a-retrospective-chart-review
#17
Robert Alan Roller, Courtney D Hall
BACKGROUND: Current vestibular rehabilitation for peripheral vestibular hypofunction is an exercise-based approach that improves symptoms and function in most, but not all patients, and includes gaze stabilization exercises focused on duration of head movement. One factor that may impact rehabilitation outcomes is the speed of head movement during gaze stability exercises. OBJECTIVE: Examine outcomes of modified VOR X1 exercises that emphasize a speed-based approach for gaze stabilization while omitting substitution and habituation exercises...
April 18, 2018: Journal of Vestibular Research: Equilibrium & Orientation
https://www.readbyqxmd.com/read/29679170/light-localization-with-low-contrast-targets-in-a-patient-implanted-with-a-suprachoroidal-transretinal-stimulation-retinal-prosthesis
#18
Takao Endo, Takashi Fujikado, Masakazu Hirota, Hiroyuki Kanda, Takeshi Morimoto, Kohji Nishida
PURPOSE: To evaluate the improvement in targeted reaching movements toward targets of various contrasts in a patient implanted with a suprachoroidal-transretinal stimulation (STS) retinal prosthesis. METHODS: An STS retinal prosthesis was implanted in the right eye of a 42-year-old man with advanced Stargardt disease (visual acuity: right eye, light perception; left eye, hand motion). In localization tests during the 1-year follow-up period, the patient attempted to touch the center of a white square target (visual angle, 10°; contrast, 96, 85, or 74%) displayed at a random position on a monitor...
April 20, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29675387/comparison-of-optical-quality-after-implantable-collamer-lens-implantation-and-wavefront-guided-laser-in-situ-keratomileusis
#19
Hong-Ting Liu, Zhou Zhou, Wu-Qiang Luo, Wen-Jing He, Owhofasa Agbedia, Jiang-Xia Wang, Jian-Zhong Huang, Xin Gao, Min Kong, Min Li, Li Li
AIM: To compare the optical quality after implantation of implantable collamer lens (ICL) and wavefront-guided laser in situ keratomileusis (WG-LASIK). METHODS: The study included 40 eyes of 22 patients with myopia who accepted ICL implantation and 40 eyes of 20 patients with myopia who received WG-LASIK. Before surgery and three months after surgery, the objective scattering index (OSI), the values of modulation transfer function (MTF) cutoff frequency, Strehl ratio, and the Optical Quality Analysis System (OQAS) values (OVs) were accessed...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29673571/the-effect-of-hospital-acuity-on-severe-maternal-morbidity-in-high-risk-patients
#20
Mark A Clapp, Kaitlyn E James, Anjali J Kaimal
BACKGROUND: In 2015, the Society for Maternal-Fetal Medicine and the American College of Obstetricians and Gynecologists published guidelines that established levels of maternal care. These guidelines outline the nursing, provider, and facility requirements for hospitals to be designated a birthing center or one of four levels of care. To-date, these levels of maternal care have not been widely adopted, and currently, no data exists on how these designations may affect maternal or neonatal outcomes...
April 16, 2018: American Journal of Obstetrics and Gynecology
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