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https://www.readbyqxmd.com/read/28736470/structural-functional-relationships-between-eye-orbital-imaging-biomarkers-and-clinical-visual-assessments
#1
Xiuya Yao, Shikha Chaganti, Kunal P Nabar, Katrina Nelson, Andrew Plassard, Rob L Harrigan, Louise A Mawn, Bennett A Landman
Eye diseases and visual impairment affect millions of Americans and induce billions of dollars in annual economic burdens. Expounding upon existing knowledge of eye diseases could lead to improved treatment and disease prevention. This research investigated the relationship between structural metrics of the eye orbit and visual function measurements in a cohort of 470 patients from a retrospective study of ophthalmology records for patients (with thyroid eye disease, orbital inflammation, optic nerve edema, glaucoma, intrinsic optic nerve disease), clinical imaging, and visual function assessments...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28736224/dichoptic-training-in-adults-with-amblyopia-additional-stereoacuity-gains-over-monocular-training
#2
Xiang-Yun Liu, Jun-Yun Zhang
Dichoptic training is a recent focus of research on perceptual learning in adults with amblyopia, but whether and how dichoptic training is superior to traditional monocular training is unclear. Here we investigated whether dichoptic training could further boost visual acuity and stereoacuity in monocularly well-trained adult amblyopic participants. During dichoptic training the participants used the amblyopic eye to practice a contrast discrimination task, while a band-filtered noise masker was simultaneously presented in the non-amblyopic eye...
July 20, 2017: Vision Research
https://www.readbyqxmd.com/read/28734565/topical-brinzolamide-in-congenital-nystagmus-a-retrospective-study
#3
M Nieves-Moreno, L Morales Fernández, B Domingo Gordo, E Maillo, E Diaz, R Gómez-de-Liaño
OBJECTIVE: To evaluate the effect of treatment with topical brinzolamide on visual acuity and nystagmus intensity in patients with congenital nystagmus. MATERIAL AND METHODS: A retrospective study was designed in which the clinical records of 14 patients with congenital nystagmus were reviewed. All patients underwent a complete ophthalmological examination and a Perea video-oculography (VOG) before, and three days after, initiation of treatment with topical brinzolamide (Azopt)...
July 19, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28731052/real-world-visual-acuity-outcomes-between-ranibizumab-and-aflibercept-in-treatment-of-neovascular-amd-in-a-large-us-data-set
#4
A Lotery, R Griner, A Ferreira, F Milnes, P Dugel
PurposeTo examine 12-month real-world visual acuity outcomes and treatment patterns in neovascular age-related macular degeneration (nAMD) eyes, including those with pigment epithelial detachment (PED), receiving ranibizumab or aflibercept.Patients and methodsElectronic medical records were used to identify ranibizumab or aflibercept-treated nAMD eyes with 12 months follow-up from first prescription. The primary objective was to compare mean change in visual acuity (VA) between index and month 12, in eyes treated with ranibizumab and aflibercept to assess the non-inferiority of ranibizumab vs aflibercept using a -5 letter non-inferiority margin...
July 21, 2017: Eye
https://www.readbyqxmd.com/read/28730085/ocular-surface-evaluation-in-eyes-with-chronic-glaucoma-on-long-term-topical-antiglaucoma-therapy
#5
Manu Saini, Murugesan Vanathi, Tanuj Dada, Tushar Agarwal, Rebika Dhiman, Sudarshan Khokhar
AIM: To evaluate ocular surface changes and its correlation with the central corneal subbasal nerve fibre layer in chronic glaucoma patients. METHODS: A prospective comparative study of ocular surface evaluation was performed in 50 eyes of 25 patients using two or more antiglaucoma medications for at least 6mo and 50 eyes of 25 normal subjects without any ocular problems as controls. The study parameters evaluated included visual acuity, intraocular pressure, ocular surface evaluation parameters [fluorescein break-up time (FTBUT), Schirmer's I test, ocular surface staining scores and ocular surface disease index score (OSDI)], central corneal sensation (Cochet Bonnett aesthesiometer), central subbasal nerve fiber layer density (SBNFLD) by confocal microscopy...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28730082/evaluation-of-visual-quality-of-spherical-and-aspherical-intraocular-lenses-by-optical-quality-analysis-system
#6
Yan Chen, Xue Wang, Chuan-Di Zhou, Qiang Wu
AIM: To evaluate the impact of spherical and aspherical intraocular lenses on the postoperative visual quality of age-related cataract patients using Optical Quality Analysis System (OQAS). METHODS: Seventy-four eyes with age-related cataracts were randomly divided into spherical and aspherical lens implantation groups. Best-corrected visual acuity (BCVA) was measured preoperatively, one day, one week, two weeks, one month and two months after surgery. A biometric systems analysis using the OQAS objective scattering index (OSI) was performed...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28728282/-epidemiologic-study-of-tear-film-lipid-layer-thickness-measurement-in-the-population-of-taishitun-community-in-beijing
#7
Q F Liang, X H Du, Y D Su, N L Wang, Z J Wei, Antoine Labbé
Objective: To investigate the distribution of tear film lipid layer thickness (LLT) and the relationship between symptoms and signs of dry eye and tear film LLT in the population of Taishitun Community in Beijing. Methods: A cross-sectional study. From May 2016 to August 2016, three streets of Taishitun Community were randomly selected as survey districts and 540 persons were taken as investigation subjects. Every participant completed 6 items of dry eye examinations as follows: questionnaire (Ocular Surface Disease Index, OSDI), measurement of tear film LLT, tear film break-up time (TBUT), corneal and conjunctival staining, SchirmerⅠtest and the infrared meibomian photography...
July 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28720723/profile-and-outcomes-of-critically-ill-children-in-a-lower-middle-income-country
#8
Muhammad Irfan Habib, Khalid Mehmood A Khan
OBJECTIVE: To determine the clinical profile and outcome of critically ill children presenting to a paediatric ED in a lower middle-income country. METHODS: We performed a retrospective analysis of children (<14 years) presenting to the ED of the National Institute of Child Health, Karachi, between January and December 2014 who were assigned to acuity 1 (requiring immediate life-saving interventions) according to the Emergency Severity Index. Data included demographic variables, presenting complaints, interventions and outcomes in the ED...
July 18, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28702257/the-relationship-between-diabetes-mellitus-and-30-day-readmission-rates
#9
Stephanie Ostling, Jennifer Wyckoff, Scott L Ciarkowski, Chih-Wen Pai, Hae Mi Choe, Vinita Bahl, Roma Gianchandani
BACKGROUND: It is estimated that 9.3% of the population in the United States have diabetes mellitus (DM), 28% of which are undiagnosed. The high prevalence of DM makes it a common comorbid condition in hospitalized patients. In recent years, government agencies and healthcare systems have increasingly focused on 30-day readmission rates to determine the complexity of their patient populations and to improve quality. Thirty-day readmission rates for hospitalized patients with DM are reported to be between 14...
2017: Clinical Diabetes and Endocrinology
https://www.readbyqxmd.com/read/28699940/association-of-stress-biomarkers-with-30-day-unplanned-readmission-and-death
#10
Carole Aubert, Antoine Folly, Mancinetti Marco, Daniel Hayoz, Jacques Donze
BACKGROUND: The theory that posthospitalization stress might increase the risk of postdischarge complications has never been investigated. OBJECTIVE: To assess whether serum levels of stress biomarkers at discharge are associated with readmission and death after an acute-care hospitalization. DESIGN: We prospectively included 346 patients aged ≥50 years admitted to the department of general internal medicine at a large community hospital between April 8, 2013 and September 23, 2013...
July 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28693519/tracing-the-natural-course-of-visual-acuity-and-quality-of-life-in-neovascular-age-related-macular-degeneration-a-systematic-review-and-quality-of-life-study
#11
Mari Elshout, Carroll A Webers, Margriet I van der Reis, Yvonne de Jong-Hesse, Jan S Schouten
BACKGROUND: Describing the natural course of neovascular age-related macular degeneration (nAMD) is essential in discussing prognosis and treatment options with patients and to support cost-effectiveness studies. METHODS: First, we performed a literature search in PubMed, Embase, and Cochrane. We included randomized clinical trials and prospective observational studies reporting visual acuity (VA) in non-treated patients, 24 studies in total. We integrated VA data using best fit on Lineweaver-Burke plots and modelled with non-linear regression using reciprocal terms...
July 11, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28683793/comparison-of-visual-results-and-higher-order-aberrations-after-small-incision-lenticule-extraction-smile-high-myopia-vs-mild-to-moderate-myopia
#12
Hong-Ying Jin, Ting Wan, Fang Wu, Ke Yao
BACKGROUND: To compare the refractive results and higher-order aberrations (HOAs) after small incision lenticule extraction (SMILE) in high myopia and mild to moderate myopia patients. METHODS: This prospective study included 165 eyes (86 patients) undergoing SMILE. According to the preoperative spherical equivalent (SE), treated eyes were divided into two groups: the high myopia group (more than -6.0 D, group-H) and the mild to moderate group (less than -6.0 D, group-M)...
July 6, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28682154/visual-search-tasks-measurement-of-dynamic-visual-lobe-and-relationship-with-display-movement-velocity
#13
Lin-Dong Yang, Rui-Feng Yu, Xue-Lian Lin, Ya-Qing Xie, Liang Ma
Visual lobe is a useful tool for predicting visual search performance. Up till now, no study has focused on dynamic visual lobe. This study developed a Dynamic Visual Lobe Measurement System (DVLMS) that could effectively map dynamic visual lobe and calculate visual lobe shape indices. The effects of display movement velocity on lobe shape indices were examined under four velocity conditions: 0, 4, 8, and 16 deg/s. In general, with the increase of display movement velocity, visual lobe area and perimeter became smaller, whereas lobe shape roundness, boundary smoothness, symmetry, and regularity deteriorated...
July 6, 2017: Ergonomics
https://www.readbyqxmd.com/read/28681909/medium-to-long-term-results-of-corneal-cross-linking-for-keratoconus-using-phototherapeutic-keratectomy-for-epithelial-removal-and-partial-stromal-ablation
#14
Xiangjun Chen, Aleksandar Stojanovic, Yangyang Xu, Wen Zhou, Sten Raeder, Sam Enayati, Tor Paaske Utheim
PURPOSE: To evaluate the medium- to long-term outcomes of corneal cross-linking in treatment of keratoconus using transepithelial phototherapeutic keratectomy (PTK-CXL) for epithelial removal and partial stromal ablation to stabilize the cornea, reduce corneal irregularity, and improve corrected vision. METHODS: Retrospective analysis of 46 keratoconic eyes that underwent PTK-CXL. Corrected distance visual acuity (CDVA), manifest refraction, steep and flat simulated keratometry (Kmax and Kmin), corneal irregularity index (IRI), corneal higher order aberrations (HOAs), epithelial thickness profile, and corneal biomechanical characteristics were evaluated preoperatively and postoperatively...
July 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28680520/validation-of-different-pediatric-triage-systems-in-the-emergency-department
#15
Kanokwan Aeimchanbanjong, Uthen Pandee
BACKGROUND: Triage system in children seems to be more challenging compared to adults because of their different response to physiological and psychosocial stressors. This study aimed to determine the best triage system in the pediatric emergency department. METHODS: This was a prospective observational study. This study was divided into two phases. The first phase determined the inter-rater reliability of five triage systems: Manchester Triage System (MTS), Emergency Severity Index (ESI) version 4, Pediatric Canadian Triage and Acuity Scale (CTAS), Australasian Triage Scale (ATS), and Ramathibodi Triage System (RTS) by triage nurses and pediatric residents...
2017: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28673750/quality-of-vision-in-eyes-with-epiphora-undergoing-lacrimal-passage-intubation
#16
Shizuka Koh, Yasushi Inoue, Shintaro Ochi, Yoshihiro Takai, Naoyuki Maeda, Kohji Nishida
PURPOSE: To investigate visual function and optical quality in eyes with epiphora undergoing lacrimal passage intubation. DESIGN: Prospective case series. METHODS: Thirty-four eyes of 30 patients with lacrimal passage obstruction were enrolled. Before and 1 month after lacrimal passage intubation, functional visual acuity (FVA), higher-order aberrations (HOAs), lower tear meniscus and tear clearance were assessed. An FVA measurement system was used to examine changes in continuous visual acuity (VA) over time, and visual function parameters such as FVA, visual maintenance ratio, and blink frequency were obtained...
June 30, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28670981/keep-an-eye-out-a-rare-case-of-acute-onset-charles-bonnet-syndrome-after-stanford-type-a-aortic-dissection-repair-surgery
#17
Fabian Cook, Scott Dougherty, Robert Moreton, Maziar Khorsandi
Charles Bonnet Syndrome describes the triad of complex visual hallucinations secondary to ophthalmic pathology in psychologically normal people. We present a rare case of acute-onset Charles Bonnet Syndrome following cardiac surgery that resulted in profound loss of visual acuity in both eyes with characteristic visual hallucinations that were initially mistaken for delirium. Computed tomography of the brain revealed bilateral occipital infarcts, providing the substrate for Charles Bonnet Syndrome. A high index of suspicion should be maintained in cognitively intact patients with visual loss who are also experiencing visual hallucinations to ensure prompt diagnosis and management of this often overlooked condition...
May 2017: Scottish Medical Journal
https://www.readbyqxmd.com/read/28670502/impact-of-glaucoma-and-dry-eye-on-text-based-searching
#18
Michelle J Sun, Gary S Rubin, Esen K Akpek, Pradeep Y Ramulu
PURPOSE: We determine if visual field loss from glaucoma and/or measures of dry eye severity are associated with difficulty searching, as judged by slower search times on a text-based search task. METHODS: Glaucoma patients with bilateral visual field (VF) loss, patients with clinically significant dry eye, and normally-sighted controls were enrolled from the Wilmer Eye Institute clinics. Subjects searched three Yellow Pages excerpts for a specific phone number, and search time was recorded...
June 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28667904/somatosensory-impairment-and-its-association-with-balance-limitation-in-people-with-multiple-sclerosis
#19
Akram Jamali, Ebrahim Sadeghi-Demneh, Niloufar Fereshtenajad, Susan Hillier
BACKGROUND: Somatosensory impairments are common in multiple sclerosis. However, little data are available to characterize the nature and frequency of these problems in people with multiple sclerosis. OBJECTIVE: To investigate the frequency of somatosensory impairments and identify any association with balance limitations in people with multiple sclerosis. METHODS: The design was a prospective cross-sectional study, involving 82 people with multiple sclerosis and 30 healthy controls...
June 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28667219/associations-between-maternal-size-and-health-outcomes-for-women-undergoing-caesarean-section-a-multicentre-prospective-observational-study-the-mum-size-study
#20
Alicia Therese Dennis, Karen Elaine Lamb, David Story, Michelle Tew, Kim Dalziel, Philip Clarke, Jospeh Lew, Anna Parker, Elizabeth Hessian, Gyln Teale, Scott Simmons, Dan Casalaz
OBJECTIVES: To investigate associations between maternal body mass index (BMI) at delivery (using pregnancy-specific BMI cut-off values 5 kg/m(2) higher in each of the WHO groups) and clinical, theatre utilisation and health economic outcomes for women undergoing caesarean section (CS). DESIGN: A prospective multicentre observational study. SETTING: Seven secondary or tertiary referral obstetric hospitals. PARTICIPANTS: One thousand and four hundred and fifty-seven women undergoing all categories of CS...
June 30, 2017: BMJ Open
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