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M Heinemann, S G Welker, F G Holz, R P Finger
BACKGROUND AND OBJECTIVES: Physical activity (PA) impacts age-related diseases but its measurement is difficult. The acceptance of wrist-worn accelerometers (ACC) in older patients with eye diseases was evaluated and the results were compared with a validated activity questionnaire. MATERIALS AND METHODS: In this study 50 patients underwent a clinical examination and were interviewed with the International Physical Activity Questionnaire (IPAQ). They then wore an ACC for 7 days and then for 30 days...
March 21, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Robert J Morrison, Kelly M Malloy, Rishi R Bakshi
Objective To assess the impact of implementation of a "1-step" documentation query system on comorbidity capture and quality outcomes within the Department of Otolaryngology-Head and Neck Surgery. Methods Implementation of the 1-step documentation query system was instituted for all otolaryngology-head and neck surgery faculty at a single institution. Individual query responses and impact metrics were analyzed. Departmental case-mix index (CMI), risk of mortality (ROM), and severity of illness (SOI) were collated over a 14-month implementation period and compared to a 12-month preimplementation period...
March 1, 2018: Otolaryngology—Head and Neck Surgery
Shilei Cui, Hanqiu Jiang, Jingting Peng, Jiawei Wang, Xiaojun Zhang
OBJECTIVE: To assess quality of life (QoL) measures in Chinese Leber hereditary optic neuropathy (LHON) patients with the G11778A mutation. METHODS: Chinese LHON patients with the G11778A mutation were prospectively evaluated using the Visual Function Index (VF-14) at 6 months, 1 year, and 3 years after the involvement of the second eye. Patients who completed the VF-14 at all 3 follow-up time designations were included in the analysis. RESULTS: Fifty-five patients met the inclusion criteria...
March 16, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
Masha Shulkin, Laura Pimpin, David Bellinger, Sarah Kranz, Wafaie Fawzi, Christopher Duggan, Dariush Mozaffarian
Background: Epidemiologic studies link maternal seafood and n-3 (ω-3) polyunsaturated fatty acid (PUFA) consumption with improved childhood cognitive development; trials show mixed results. Objective: We investigated effects of n-3 PUFA supplementation on child cognitive and visual outcomes. Methods: We systematically reviewed and meta-analyzed randomized controlled trials of n-3 PUFA supplementation in mothers or infants (age ≤2 y) and evaluated standardized measures of cognitive or visual development up to age 18 y...
March 1, 2018: Journal of Nutrition
O A Konikova, V V Brzhesky
Visual impairment in children with regressive retinopathy of prematurity (ROP) are diverse and widespread. PURPOSE: to describe the electrophysiological characteristics of the retina in children with I-V stages of regressive ROP. MATERIAL AND METHODS: The study included children with stages I-V aged 5 to 17 (in the disease stages of IV and V - with reattachment of the retina after surgical treatment of its detachment). Patients with concomitant diseases of the eye were excluded from the study...
2018: Vestnik Oftalmologii
Feray Koc, Mehmet Resit Isik, Nazife Sefi-Yurdakul
PURPOSE: To evaluate the correlation between weight reduction and visual outcome in overweight patients with idiopathic intracranial hypertension. METHODS: Thirty-nine newly diagnosed, overweight (body mass index >25 kg/m2) patients with idiopathic intracranial hypertension were studied retrospectively. All patients underwent medical treatment with acetazolamide, and a weight reduction program was also offered. Patients were grouped according to their compliance with this weight reduction program into the diet-success (Group 1) and diet-failure groups (Group 2)...
January 2018: Arquivos Brasileiros de Oftalmologia
Giancarlo A Garcia, Matin Khoshnevis, Kenneth M P Yee, Justin H Nguyen, Jeannie Nguyen-Cuu, Alfredo A Sadun, J Sebag
PURPOSE: Contrast sensitivity function (CSF) declines with age. When unassociated with cataracts, this is hypothesized to be due to macular ganglion cell complex (GCC) thinning. However, other studies found associations with increased vitreous echodensity and posterior vitreous detachment (PVD). We investigate the relationship between CSF, vitreous echodensity, PVD, and GCC thickness as related to age in the same subjects. METHODS: Age, CSF (Weber index: %W), vitreous echodensity (quantitative ultrasonography [QUS]), lens status (phakia or pseudophakia), best-corrected visual acuity (BCVA), and GCC thickness (SD-OCT) were evaluated in 57 eyes of 57 subjects with (n = 32, mean age = 62 years) and without (n = 25, mean age = 44 years) PVD (P < 0...
March 13, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Michael T Milano, Jimm Grimm, Scott G Soltys, Ellen Yorke, Vitali Moiseenko, Wolfgang A Tomé, Arjun Sahgal, Jinyu Xue, Lijun Ma, Timothy D Solberg, John P Kirkpatrick, Louis S Constine, John C Flickinger, Lawrence B Marks, Issam El Naqa
PURPOSE: Dosimetric and clinical predictors of radiation-induced optic nerve/chiasm neuropathy (RION) after single-fraction stereotactic radiosurgery (SRS) or hypofractionated (2-5 fractions) radiosurgery (fSRS) were analyzed from pooled data that were extracted from published reports (PubMed indexed from 1990 to June 2015). This study was undertaken as part of the American Association of Physicists in Medicine Working Group on Stereotactic Body Radiotherapy, investigating normal tissue complication probability (NTCP) after hypofractionated radiation...
January 31, 2018: International Journal of Radiation Oncology, Biology, Physics
Terence A Imbery, Dan Tran, Mary A Baechle, Jennifer L Hankle, Charles Janus
PURPOSE: To determine if Farnsworth-Munsell 100 Hue Test, Perceptual Ability Test, gender, age, ethnicity, and time predict dental shade matching and value discernment in first-year dental students. MATERIALS AND METHODS: Farnsworth-Munsell 100 Hue Test was administered to 95 first-year-dental students beneath a Judge II booth (color temperature of 6500°K, and color rendering index of 90). Students also arranged 16 masked shade tabs from a Vita Classic shade guide by value (lightest to darkest) and matched together 16 pairs of masked shade tabs from two Vita Classic shade guides...
March 13, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
Achim Fieß, Ruth Kölb-Keerl, Alexander K Schuster, Markus Knuf, Bernd Kirchhof, Philipp S Muether, Jacqueline Bauer
PURPOSE: The objective of this study was to investigate the relationship between visual acuity, peripapillary retinal nerve fibre layer (pRNFL), retinal thickness at the fovea and other factors with the neurologic status of former preterm children. METHODS: In this cross-sectional hospital based study in a maximum care tertiary centre, detailed anthropometric and ophthalmological data of former preterm children ranging from 4 to 10 years of age with a gestational age (GA) ≤32 weeks were assessed...
March 9, 2018: Acta Ophthalmologica
Ikhyun Jun, David Sung Yong Kang, Dan Z Reinstein, Samuel Arba-Mosquera, Timothy J Archer, Kyoung Yul Seo, Tae-Im Kim
PURPOSE: To comparatively investigate the clinical outcomes, vector parameters, and corneal aberrations of small incision lenticule extraction (SMILE) with a triple centration technique and corneal wavefront-guided transepithelial photorefractive keratectomy (PRK) for the correction of high astigmatism. METHODS: This retrospective, comparative case series study included 89 eyes (89 patients) that received treatment for myopia with high astigmatism (≥ 2.50 diopters) using SMILE with a triple centration technique (SMILE group; 45 eyes) and corneal wavefront-guided transepithelial PRK (transepithelial PRK group; 44 eyes)...
March 1, 2018: Journal of Refractive Surgery
Wouter F van Leeuwen, Mariano E Menendez, Michael P Gaspar, Sidney M Jacoby, A Lee Osterman, Neal Chen
BACKGROUND: The purpose of this study was to identify factors associated with unplanned reoperation after surgery for scapholunate interosseous ligament (SLIL) insufficiency. METHODS: Using Current Procedural Terminology (CPT) codes from 3 hand surgery centers across 2 metropolitan areas, we identified 316 patients undergoing surgery for SLIL insufficiency from 2000 to 2014. Medical records were manually reviewed to collect data on factors that might be associated with unplanned reoperation, including age, sex, tobacco use, occupation, acuity of treatment, and reconstruction method...
March 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
Paula Casas, Francisco J Ascaso, Eugenio Vicente, Gloria Tejero-Garcés, María I Adiego, José A Cristóbal
BACKGROUND: To assess the retinal sensitivity in obstructive sleep apnea hypopnea syndrome (OSAHS) patients evaluated with standard automated perimetry (SAP). And to correlate the functional SAP results with structural parameters obtained with optical coherence tomography (OCT). METHODS: This prospective, observational, case-control study consisted of 63 eyes of 63 OSAHS patients (mean age 51.7 ± 12.7 years, best corrected visual acuity ≥20/25, refractive error less than three spherical or two cylindrical diopters, and intraocular pressure < 21 mmHg) who were enrolled and compared with 38 eyes of 38 age-matched controls...
March 2, 2018: BMC Ophthalmology
Ewa Zamysłowska-Szmytke, Sylwia Szostek-Rogula, Mariola Śliwińska-Kowalska
BACKGROUND: Balance assessment relies on symptoms, clinical examination and functional assessment and their verification in objective tests. Our study was aimed at calculating the assessment compatibility between questionnaires, functional scales and objective vestibular and balance examinations. MATERIAL AND METHODS: A group of 131 patients (including 101 women; mean age: 59±14 years) of the audiology outpatient clinic was examined. Benign paroxysmal positional vertigo, phobic vertigo and central dizziness were the most common diseases observed in the study group...
February 28, 2018: Medycyna Pracy
Masahiro Okamoto, Mariko Yamashita, Nahoko Ogata
PURPOSE: To determine the effects of an intravitreal injection of ranibizumab (IVR) on the choroidal structure and blood flow in eyes with diabetic macular edema (DME). METHODS: Twenty-eight consecutive patients with DME who received an IVR and 20 non-diabetic, age-matched controls were followed for 1 month. The eyes with DME were divided into those with prior panretinal photocoagulation (PRP, n = 16) and those without prior PRP (no-PRP, n = 12). The enhanced depth imaging optical coherence tomography (EDI-OCT) scans and Niblack's image binarization were performed to determine the choroidal structure...
March 1, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Daniela Claessens, Alexander K Schuster
BACKGROUND: Amsler Test is the standard used to detect metamorphopsia. To develop a tool to quantitatively measure and monitor metamorphopsia, the computer-based test "AMD - A Metamorphopsia Detector® " was developed. This study was performed to examine the correlation of metamorphopsia index (MI) and central retinal thickness (CRT) in exsudative age-related macular degeneration (AMD) and diabetic macular edema (DME). MATERIAL AND METHODS: Sixty-six eyes of 66 patients, DME: 19 (11 males, 8 females; age 42 - 76); AMD: 47 (13 male, 34 female; age 56 - 93) were included in this convenient sample study and classified as having or not having macular edema (central 500 µm, Cirrus HD-OCT)...
February 28, 2018: Klinische Monatsblätter Für Augenheilkunde
Sandra Rezar-Dreindl, Katharina Eibenberger, Wolf Buehl, Günther Weigert, Michael Georgopoulos, Ursula Schmidt-Erfurth, Stefan Sacu
BACKGROUND: To evaluate the change in peripheral perfusion status in patients with retinal vein occlusion (RVO) during dexamethasone treatment. METHODS: Thirty-five eyes of patients with macular oedema due to either branch or central retinal vein occlusion were included. At baseline, patients were treated with an intravitreal dexamethasone implant (Ozurdex® ) and followed until month 6. Wide-field angiographies were classified as ischaemic and nonischaemic. Peripheral nonperfusion (PNP) was determined manually by calculating the percentage of nonperfusion area in relation to the total visible retina (ischaemic index)...
February 27, 2018: Acta Ophthalmologica
John C Markley, Michaela K Farber, Nicola C Perlman, Daniela A Carusi
BACKGROUND: General anesthesia (GA) is often selected for cesarean deliveries (CD) with placenta previa and suspected morbidly adherent placenta (MAP) due to increased risk of hemorrhage and hysterectomy. We reviewed maternal outcomes and risk factors for conversion to GA in a cohort of patients undergoing CD and hysterectomy under neuraxial anesthesia (NA). METHODS: We performed a single-center, retrospective cohort study of parturients undergoing nonemergent CD for placenta previa with suspected MAP from 1997 to 2015...
February 23, 2018: Anesthesia and Analgesia
Paul Harmatz, Chester B Whitley, Raymond Y Wang, Mislen Bauer, Wenjie Song, Christine Haller, Emil Kakkis
BACKGROUND: Drug development for ultra-rare diseases is challenging because small sample sizes and heterogeneous study populations hamper the ability of randomized, placebo-controlled trials with a single primary endpoint to demonstrate valid treatment effects. METHODS: To overcome these challenges, a novel Blind Start design was utilized in a study of vestronidase alfa in mucopolysaccharidosis VII (Sly syndrome), an ultra-rare lysosomal disease, that demonstrates the strengths of this approach in a challenging drug-development setting...
February 12, 2018: Molecular Genetics and Metabolism
Christopher S Hollenbeak, Amber L Schilling
BACKGROUND: Catheter-associated urinary tract infections (CAUTIs) are the most common healthcare-acquired condition. The attributable cost of CAUTIs is frequently cited to be approximately $1,000. However, there is a paucity of recent literature that confirms this estimate. The purpose of this study was to perform a systematic review of the literature that estimates the attributable cost of CAUTIs in the United States. METHODS: A systematic review was conducted using Pubmed...
February 22, 2018: American Journal of Infection Control
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