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https://www.readbyqxmd.com/read/28524639/high-dose-intravenous-steroid-pulse-therapy-in-ocular-involvement-of-behcet-s-disease-a-pilot-double-blind-control-study
#1
Mastaneh Mohammadi, Farhad Shahram, Hormoz Shams, Massoomeh Akhlaghi, Farimah Ashofteh, Fereydoun Davatchi
AIM: To evaluate the efficacy of intravenous high-dose pulses of methylprednisolone (IVPM) for treatment of ocular involvement in Behcet's disease (BD). METHOD: In a double-blind control study, we randomized BD patients with posterior uveitis (PU) and/or retinal vasculitis (RV) into two groups. They received either IVPM (1000 mg methylprednisolone) or placebo for 3 consecutive days. Both groups received combination therapy with IV cyclophosphamide, azathioprine and prednisolone for 6 months...
May 19, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28521183/predictors-of-poor-visual-outcome-in-patients-with-idiopathic-intracranial-hypertension-iih-an-ambispective-cohort-study
#2
Amit Agarwal, Deepti Vibha, Kameshwar Prasad, Rohit Bhatia, Mamta Bhushan Singh, Ajay Garg, Rohit Saxena
OBJECTIVE: Idiopathic intracranial hypertension (IIH) is a disease of young with threat to vision if not diagnosed timely. This study looked at the putative predictors of poor visual outcome in patients with IIH at six months after presentation via a cohort study. PATIENTS AND METHODS: All patients diagnosed with IIH from January 2011 to May 2015 were enrolled. The study design was ambispective cohort study. The baseline clinical and radiological characteristics assessed were age, sex, body mass index (BMI), duration of symptoms, transient visual obscuration, cranial nerve palsy, diminution of vision, Cerebrospinal fluid (CSF) opening pressure, empty sella, optic nerve dilatation, global configuration and transverse sinus stenosis...
May 10, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28514829/does-hofstetter-s-equation-predict-the-real-amplitude-of-accommodation-in-children
#3
Hassan Hashemi, Payam Nabovati, Mehdi Khabazkhoob, Abbasali Yekta, Mohammad Hassan Emamian, Akbar Fotouhi
PURPOSE: The aim was to determine the distribution and associated factors of accommodative amplitude (AA) in six- to 12-year-old children and compare the results with those calculated using Hofstetter's formula. METHODS: In a cross-sectional study in 2015, random sampling was done from urban and rural populations of Shahroud, northern Iran. Participating schoolchildren were examined for manifest, cycloplegic and subjective refraction, as well as uncorrected vision and visual acuity...
May 17, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28503438/comparison-of-visual-effects-of-fs-lasik-for-myopia-centered-on-the-coaxially-sighted-corneal-light-reflex-or-the-line-of-sight
#4
Jing Zhang, Shi-Sheng Zhang, Qin Yu, Jing-Cai Lian
AIM: To compare visual quality after femtosecond laser in situ keratomileusis (FS-LASIK), between the coaxially sighted corneal light reflex (CSCLR) group and conventional ablation line of sight (LOS) group. METHODS: In total, 243 eyes (122 patients) were treated with centration on the CSCLR (visual axis) and 238 eyes (119 patients) treated with centration on the pupil center (LOS). Postoperative outcomes [uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA)], safety index, efficacy index, refractive outcome, ablation center distance from the visual axis, corneal high-order aberrations, subjective discomfort glare and shadowing incidence rate, and contrast sensitivity at 1, 3, and 6mo were measured and compared...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28503437/comparison-of-postoperative-optical-quality-according-to-the-degree-of-decentering-of-v4c-implantable-collamer-lens
#5
Min Ji Park, Hye Min Jeon, Kyoung Heon Lee, Sang Youp Han
AIM: To evaluate the clinical outcomes of V4c implantable collamer lens (Hole ICL) implantation with regard to the optical quality assessed according to different degrees of decentering. METHODS: This included 49 eyes that received conventional ICL and 94 eyes that received Hole ICL. The eyes that received Hole ICL were divided into three groups according to the degree of decentering: group 1, central hole within 1 hole diameter (HD) from the pupil center; group 2, central hole within 1 HD to 2 HD; and group 3, central hole within 2 HD to 3 HD...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28497412/improved-mortality-outcomes-over-time-for-weekend-emergency-medical-admissions
#6
R Conway, S Cournane, D Byrne, D O'Riordan, B Silke
BACKGROUND: Multiple studies have suggested an association between weekend hospital admissions and mortality. These have been limited by potential residual confounders and a lack of explanation of causation. AIM: We previously attributed adverse weekend outcomes to higher acuity; we have re-examined this question for all emergency medical admissions to our institution from 2002 to 2014. METHODS: We divided admissions by a weekday or weekend (Friday to Sunday) hospital arrival...
May 11, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28495431/evolution-of-australian-percutaneous-coronary-intervention-from-the-melbourne-interventional-group%C3%A2-mig-registry
#7
Julian Yeoh, Matias B Yudi, Nick Andrianopoulos, Bryan P Yan, David J Clark, Stephen J Duffy, Angela Brennan, Gishel New, Melanie Freeman, David Eccleston, Martin Sebastian, Christopher M Reid, William Wilson, Andrew E Ajani
Percutaneous coronary intervention (PCI) continues to evolve with shifting patient demographics, treatments, and outcomes. We sought to document the specific changes observed over a 9-year period in a contemporary Australian PCI cohort. The Melbourne Interventional Group is an established multicenter PCI registry in Melbourne, Australia. Data were collected prospectively with 30-day and 12-month follow-ups. Demographic, procedural, and outcome data for all consecutive patients were analyzed with a year-to-year comparison from 2005 to 2013...
April 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28489750/performance-of-the-lace-index-to-identify-elderly-patients-at-high-risk-for-hospital-readmission-in-singapore
#8
Lian Leng Low, Nan Liu, Marcus Eng Hock Ong, Eileen Yining Ng, Andrew Fu Wah Ho, Julian Thumboo, Kheng Hock Lee
Unplanned readmissions may be avoided by accurate risk prediction and appropriate resources could be allocated to high risk patients. The Length of stay, Acuity of admission, Charlson comorbidity index, Emergency department visits in past six months (LACE) index was developed to predict hospital readmissions in Canada. In this study, we assessed the performance of the LACE index in a Singaporean cohort by identifying elderly patients at high risk of 30-day readmissions. We further investigated the use of additional risk factors in improving readmission prediction performance...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28489719/microkeratome-assisted-anterior-lamellar-keratoplasty-for-the-correction-of-high-degree-postkeratoplasty-astigmatism
#9
Shay Gutfreund, Pia Leon, Massimo Busin
PURPOSE: To describe the surgical technique and report the outcomes of patients treated with microkeratome-assisted anterior lamellar keratoplasty (MALK) for the correction of high-degree postkeratoplasty astigmatism. METHODS: Four eyes of 2 patients with extremely high (>10 D) and irregular [surface asymmetry index >1.0 D] post-penetrating keratoplasty astigmatism occurring after complete suture removal underwent MALK and were followed for at least 3 years after the procedure...
May 9, 2017: Cornea
https://www.readbyqxmd.com/read/28486721/topography-guided-lasik-versus-small-incision-lenticule-extraction-smile-for-myopia-and-myopic-astigmatism-a-randomized-prospective-contralateral-eye-study
#10
Anastasios John Kanellopoulos
PURPOSE: To compare safety and efficacy of topography-guided LASIK and contralateral eye SMILE for myopia and myopic astigmatism correction. METHODS: This prospective, randomized contralateral eye study included 44 eyes of 22 patients with bilateral myopia or myopic astigmatism. Treated eyes were divided into two groups: 22 eyes were treated with topography-guided LASIK and the fellow eye of each patient was treated with SMILE. The following parameters were evaluated preoperatively and up to 3 months postoperatively: uncorrected distance vision acuity (UDVA), corrected distance vision acuity (CDVA), refractive error, corneal keratometry, contrast sensitivity, and Objective Scatter Index...
May 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28486720/comparative-analysis-of-the-clinical-outcomes-of-smile-and-wavefront-guided-lasik-in-low-and-moderate-myopia
#11
Mounir A Khalifa, Ahmed Ghoneim, Mohamed Shafik Shaheen, Mohamed G Aly, David P Piñero
PURPOSE: To compare the clinical outcomes of small incision lenticule extraction (SMILE) and wavefront-guided LASIK (WFG LASIK) in eyes with low and moderate myopia. METHODS: This was a prospective, comparative study enrolling 110 eyes with low and moderate myopia (spherical equivalent ≤ 6.00 diopters [D]). Two groups were differentiated according to the surgical technique used: the WFG LASIK group included 51 eyes (51 patients) undergoing WFG LASIK using the STAR S4IR excimer laser and the iDesign aberrometer (Abbott Medical Optics, Abbott Park, IL) and the SMILE group included 59 eyes (59 patients) undergoing SMILE with the VisuMax platform (Carl Zeiss Meditec, Jena, Germany)...
May 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28486719/customized-topography-guided-corneal-collagen-cross-linking-for-keratoconus
#12
Myriam Cassagne, Kévin Pierné, Stéphane D Galiacy, Marie-Pierre Asfaux-Marfaing, Pierre Fournié, François Malecaze
PURPOSE: To compare the efficacy and safety of topography-guided corneal collagen cross-linking (TG-CXL) to conventional corneal CXL (C-CXL) in progressive keratoconus. METHODS: In this prospective, nonrandomized clinical trial, 60 eyes of 60 patients were scheduled to receive either TG-CXL (30 eyes with deepithelialization focused on the cone, riboflavin application for 10 minutes, and 30 mW/cm(2) pulsed ultraviolet-A irradiance pattern according to topography) or C-CXL (30 eyes treated in accordance with the Dresden protocol)...
May 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28482825/effect-of-limbal-relaxing-incisions-during-implantable-collamer-lens-surgery
#13
Zhen Li, Yu Han, Budan Hu, Huibin Du, Gengsheng Hao, Xiaoxi Chen
BACKGROUND: The limbal relaxing incisions (LRIs) technique is a safe and an inexpensive procedure, which is simple for experts to perform. It can effectively reduce astigmatism and result in a rapid visual rehabilitation. But there are few reports about reducing pre-existing corneal astigmatism by LRI in ICL surgery. Our research was aimed to study the effect of limbal relaxing inci sions during implantable collamer lens (ICL) surgery. METHODS: A prospective analysis reviewing consecutive cases of corneal astigmatism that had either independent ICL surgery (control group) or combined with LRIs (LRIs group)...
May 8, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28464969/utilization-criteria-for-prehospital-ultrasound-in-a-canadian-critical-care-helicopter-emergency-medical-service-determining-who-might-benefit
#14
Domhnall O'Dochartaigh, Matthew Douma, Chris Alexiu, Shell Ryan, Mark MacKenzie
Introduction Prehospital ultrasound (PHUS) assessments by physicians and non-physicians are performed on medical and trauma patients with increasing frequency. Prehospital ultrasound has been shown to be of benefit by supporting interventions. Problem Which patients may benefit from PHUS has not been clearly identified. METHODS: A multi-variable logistic regression analysis was performed on a previously created retrospective dataset of five years of physician- and non-physician-performed ultrasound scans in a Canadian critical care Helicopter Emergency Medical Service (HEMS)...
May 3, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28463183/personalized-risk-scoring-for-critical-care-prognosis-using-mixtures-of-gaussian-processes
#15
Ahmed M Alaa, Jinsung Yoon, Scott Hu, Mihaela van der Schaar
In this paper, we develop a personalized real-time risk scoring algorithm that provides timely and granular assessments for the clinical acuity of ward patients based on their (temporal) lab tests and vital signs; the proposed risk scoring system ensures timely intensive care unit (ICU) admissions for clinically deteriorating patients. METHODS: The risk scoring system is based on the idea of sequential hypothesis testing under an uncertain time horizon. The system learns a set of latent patient subtypes from the offline electronic health record data, and trains a mixture of Gaussian Process (GP) experts, where each expert models the physiological data streams associated with a specific patient subtype...
April 27, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28457282/outcomes-after-implantable-collamer-lens-surgery-in-a-canadian-cohort
#16
Aaron T Chan, Noa A Zauberman, Clara C Chan, David S Rootman
OBJECTIVE: To describe refractive outcomes and complications after implantable collamer lens (ICL) implantation. DESIGN: Retrospective, interventional case series. METHODS: A database search of ICL surgeries over a 5-year period (2009-2013) was conducted, and 83 eyes of 44 patients were included. The Visian ICL (STAAR Surgical, Monrovia, Calif.) was used in all eyes. The primary outcome measure was postoperative uncorrected distance acuity (UCDA)...
April 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28456510/high-acuity-sleeve-gastrectomy-patients-in-a-free-standing-ambulatory-surgical-center
#17
Peter Billing, Josiah Billing, Jedediah Kaufman, Kurt Stewart, Eric Harris, Rob Landerholm
BACKGROUND: Procedures performed in ambulatory surgical centers (ASC) can provide several advantages over hospital-based surgery. Understandably, concerns have been raised regarding "high acuity" cases in the ASC setting. Recently the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) presented protocols for ASCs to follow, requiring them to perform only "low acuity" cases to be compliant with accreditation. OBJECTIVE: Assess the safety and efficacy of outpatient sleeve gastrectomy (SG) on the "high acuity patient" in a free-standing ASC...
March 27, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28446838/visual-functions-of-workers-exposed-to-organic-solvents-in-petrochemical-industries
#18
R Indhushree, R Monica, K Coral, Narayanasamy Angayarkanni, R Punitham, B M Subburathinam, R Krishnakumar, P P Santanam
AIM: The purpose of this study was to evaluate the visual functions of workers exposed to organic solvents in petrochemical industries. MATERIALS AND METHODS: Thirty workers from the petroleum refinery and 30 age-matched controls (mean age) were recruited. Visual functions and occupational exposure levels were assessed among both the groups. Visual acuity, contrast sensitivity, color vision, and visual fields were evaluated at the workplace. The biological samples, namely blood and urine, were collected at the workplace and transported to the laboratory for analysis...
September 2016: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28435215/a-comparison-of-mesopic-visual-acuity-and-objective-visual-quality-following-cataract-surgery-with-hydrophobic-acrylic-intraocular-lenses
#19
George Hh Beiko, Miso Gostimir, Lila Haj-Ahmad
PURPOSE: To evaluate mesopic visual acuity and visual quality as measured by objective scatter index (OSI) in pseudophakic eyes with long-term follow-up after implantation of hydrophobic acrylic lenses made from two different lens materials. SETTING: This study was carried out in a private clinic. DESIGN: This study was an observational cohort study. METHODS: This pilot study included 181 eyes of 136 patients who had undergone cataract surgery with implantation of monofocal hydrophobic acrylic intraocular lenses (IOLs), either Alcon AcrySof (82 eyes) or Abbott Medical Optics' Tecnis (99 eyes)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28435122/global-motion-perception-is-related-to-motor-function-in-4-5-year-old-children-born-at-risk-of-abnormal-development
#20
Arijit Chakraborty, Nicola S Anstice, Robert J Jacobs, Nabin Paudel, Linda L LaGasse, Barry M Lester, Christopher J D McKinlay, Jane E Harding, Trecia A Wouldes, Benjamin Thompson
Global motion perception is often used as an index of dorsal visual stream function in neurodevelopmental studies. However, the relationship between global motion perception and visuomotor control, a primary function of the dorsal stream, is unclear. We measured global motion perception (motion coherence threshold; MCT) and performance on standardized measures of motor function in 606 4.5-year-old children born at risk of abnormal neurodevelopment. Visual acuity, stereoacuity and verbal IQ were also assessed...
April 28, 2017: Vision Research
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