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https://www.readbyqxmd.com/read/28944733/performance-based-risk-sharing-arrangements-for-pharmaceutical-products-in-the-united-states-a-systematic-review
#1
Justin S Yu, Lauren Chin, Jennifer Oh, Jorge Farias
BACKGROUND: Value for money is a growing necessity in today's U.S. health care system in which drug spending is expected to increase by an average rate of 6.7% yearly through 2025. In response to uncertainty about real-world clinical and economic outcomes for many drugs, health insurers and pharmacy benefit managers (PBMs) have implemented various contracts and arrangements with drug manufacturers that can collectively be described as performance-based risk-sharing arrangements (PBRSAs)...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944731/the-fda-unapproved-drugs-initiative-an-observational-study-of-the-consequences-for-drug-prices-and-shortages-in-the-united-states
#2
Ravi Gupta, Sanket S Dhruva, Erin R Fox, Joseph S Ross
BACKGROUND: Hundreds of drug products are currently marketed in the United States without approval from the FDA. The 2006 Unapproved Drugs Initiative (UDI) requires manufacturers to remove these drug products from the market or obtain FDA approval by demonstrating evidence of safety and efficacy. Once the FDA acts against an unapproved drug, fewer manufacturers remain in the market, potentially enabling drug price increases and greater susceptibility to drug shortages. There is a need for systematic study of the UDI's effect on prices and shortages of all targeted drugs...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944632/-student-pursuing-a-bachelor-of-science-in-nursing-160-between-process-of-professionalization-and-professional-development-in-swiss-and-belgien
#3
Myriam Graber, Veronique Haberey-Knuessi
The predictable shortage of nursing staff, in Switzerland as in the rest of Europe, continues to highlight a recurring problem for public health policy. The issue here is not just questions about the care and treatment of patients or the quality of such care, but also about the conditions necessary for adequate staff recruitment and the long-term professional engagement of health care personnel. Training in nursing care at the Universities of Applied Science of Western Switzerland is also indirectly concerned by rationalisation measures currently in force in the public Activé par Editorial Manager® et Preprint Manager® appartenant à Aries Systems Corporation health sector...
April 19, 2017: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28944450/review-dynamic-spatial-models-of-parasite-transmission-in-wildlife-their-structure-applications-and-remaining-challenges
#4
REVIEW
L A White, J D Forester, M E Craft
1.Individual differences in contact rate can arise from host, group, and landscape heterogeneity and can result in different patterns of spatial spread for diseases in wildlife populations with concomitant implications for disease control in wildlife of conservation concern, livestock, and humans. While dynamic disease models can provide a better understanding of the drivers of spatial spread, the effects of landscape heterogeneity have only been modelled in a few well-studied wildlife systems such as rabies and bovine tuberculosis...
September 25, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28944408/etiology-of-childhood-pneumonia-what-we-know-and-what-we-need-to-know-based-on-5th-dr-ic-verma-excellence-oration-award
#5
Joseph L Mathew
Childhood community acquired pneumonia continues to be an important clinical problem at the individual, institutional and community levels. Determination of microbial etiology is critical to develop evidence-based management (therapeutic and prophylactic) decisions. For decades, the approach to this relied on culture of lung aspirate specimens obtained from children with radiographically confirmed pneumonia, before administering antibiotics. Such studies revealed the major bacteria associated with pneumonia, prompting the World Health Organization to develop a highly sensitive clinical definition of pneumonia and advocate empiric antibiotic therapy; in order to save lives (focusing on community settings lacking resources for diagnostic tests)...
September 25, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28944271/the-effect-of-passive-heating-on-heat-shock-protein-70-and-interleukin-6-a-possible-treatment-tool-for-metabolic-diseases
#6
S H Faulkner, S Jackson, G Fatania, C A Leicht
Increasing physical activity remains the most widely publicized way of improving health and wellbeing. However, in populations that benefit most from exercise (EX), adherence is often poor and alternatives to EX are important to bring about health improvements. Recent work suggests a role for passive heating (PH) and heat shock proteins (HSP) in improving cardio-metabolic health. The aim of this study was to investigate the expression of HSP70 and interleukin-6 in response to either EX or PH and the subsequent effect on glucose control...
2017: Temperature: Multidisciplinary Biomedical Journal
https://www.readbyqxmd.com/read/28943362/understanding-the-management-and-teaching-of-dental-restoration-repair-systematic-review-and-meta-analysis-of-surveys
#7
REVIEW
Philipp Kanzow, Annette Wiegand, Gerd Göstemeyer, Falk Schwendicke
OBJECTIVES: Repair instead of complete replacement is recommended to manage partially defective restorations. It is unclear if and why such treatment is taught at dental schools or practiced by dentists. We aimed to identify barriers and facilitators for repairs using a systematic review and meta- and qualitative analysis. SOURCES: Electronic databases (PubMed, CENTRAL, Embase, PsycINFO) were searched. STUDY SELECTION: Quantitative studies reporting on the proportion of (1) dentists stating to perform repairs, (2) dental schools teaching repairs, (3) failed restorations having been repaired were included...
September 21, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28943225/achieving-scale-rapidly-in-public-health-applying-business-management-principles-to-scale-up-an-hiv-prevention-program-in-india
#8
Sema K Sgaier, Aparajita Ramakrishnan, Alkesh Wadhwani, Aparajita Bhalla, Hari Menon, James Baer, Ashok Alexander
No abstract text is available yet for this article.
September 21, 2017: Healthcare
https://www.readbyqxmd.com/read/28942754/can-we-improve-the-nutritional-quality-of-meat
#9
Nigel D Scollan, Eleri M Price, Sarah A Morgan, Sharon A Huws, Kevin J Shingfield
The nutritional value of meat is an increasingly important factor influencing consumer preferences for poultry, red meat and processed meat products. Intramuscular fat content and composition, in addition to high quality protein, trace minerals and vitamins are important determinants of nutritional value. Fat content of meat at retail has decreased substantially over the past 40 years through advances in animal genetics, nutrition and management and changes in processing techniques. Evidence of the association between diet and the incidence of human non-communicable diseases has driven an interest in developing production systems for lowering total SFA and trans fatty acid (TFA) content and enrichment of n-3 PUFA concentrations in meat and meat products...
September 25, 2017: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/28941917/national-trends-in-the-management-of-primary-vesicoureteral-reflux-in-children
#10
Michael Garcia-Roig, Curtis Tavers, Courtney E McCracken, Andrew J Kirsch
OBJECTIVE: In September 2011, the American Academy of Pediatrics(AAP) released updated guidelines for workup of children 2-24 months old with a febrile urinary tract infection(UTI). We aimed to document the guideline's impact on diagnosis and surgical management of VUR at US children's hospitals. We hypothesize that VCUG studies and VUR treatment rate decreased concurrent with national guideline release. METHODS: The Pediatric Health Information System(PHIS) was queried for children(<18 years) with primary VUR, and their anti-reflux surgical history, from January 2004-June 2015...
September 20, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28941662/-welfare-state-and-public-health-the-role-of-occupational-health
#11
Fernando G Benavides, Jordi Delclós, Consol Serra
In the context of the current crisis of the Welfare State, occupational health can contribute significantly to its sustainability by facilitating decent and healthy employment throughout the working life. To this end, occupational health must take on the challenge of promoting health, preventing and managing injuries, illnesses and disability, based on better coordination of prevention services, mutual insurance companies, and health services, as well as by empowering the leadership in prevention of companies and the active participation of those who work...
September 20, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28941489/from-bench-to-bedside-the-hampton-university-skin-of-color-research-institute-2015-skin-of-color-symposium
#12
EDITORIAL
Clinton W Enos, Valerie M Harvey
The Hampton University Skin of Color Research Institute Skin of Color Symposium 2015: From Bench to Bedside was held in Williamsburg, Virginia at the Williamsburg Lodge, November 13-15, 2015. The conference was designed to promote, develop, and advance the education, knowledge, and research of cutaneous disorders disproportionately affecting people of racial and ethnic minority groups. Centered on the theme of "From Bench to Bedside", the symposium provided a program featuring a diverse panel of nationally recognized physician-scientists, basic scientists, and clinicians who updated attendees on the latest research advances across multiple relevant disciplines, including public health, basic science, and the clinical diagnosis and management of select complex and rare dermatologic conditions...
October 2017: Journal of Investigative Dermatology. Symposium Proceedings
https://www.readbyqxmd.com/read/28941113/the-efficacy-of-smartphone-based-mental-health-interventions-for-depressive-symptoms-a-meta-analysis-of-randomized-controlled-trials
#13
Joseph Firth, John Torous, Jennifer Nicholas, Rebekah Carney, Abhishek Pratap, Simon Rosenbaum, Jerome Sarris
The rapid advances and adoption of smartphone technology presents a novel opportunity for delivering mental health interventions on a population scale. Despite multi-sector investment along with wide-scale advertising and availability to the general population, the evidence supporting the use of smartphone apps in the treatment of depression has not been empirically evaluated. Thus, we conducted the first meta-analysis of smartphone apps for depressive symptoms. An electronic database search in May 2017 identified 18 eligible randomized controlled trials of 22 smartphone apps, with outcome data from 3,414 participants...
October 2017: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
https://www.readbyqxmd.com/read/28940523/epidemiology-of-helicobacter-pylori-infection-in-asymptomatic-schoolchildren-in-bhutan
#14
Sonam Wangda, James M Richter, Pema Kuenzang, Kinley Wangchuk, Tashi Choden, Karma Tenzin, Hoda M Malaty
AIM: Bhutan is a small mountainous country between Tibet and India with relatively homogenous population. According to the World Health Organization, gastric cancer is the most frequent cause of cancer death in Bhutan. This study examined the prevalence of Helicobacter pylori among children in Bhutan with emphasis on water source and living conditions. METHODS: A cross-sectional sero-epidemiologic study was conducted among schoolchildren who attended public schools in Thimphu, Bhutan...
September 22, 2017: Helicobacter
https://www.readbyqxmd.com/read/28938880/-keeping-family-matters-behind-closed-doors-healthcare-providers-perceptions-and-experiences-of-identifying-and-managing-domestic-violence-during-and-after-pregnancy
#15
Mary McCauley, Jennifer Head, Jaki Lambert, Shamsa Zafar, Nynke van den Broek
BACKGROUND: Violence against women is an international public health concern and a violation of women's rights. Domestic violence can first occur, and increase in frequency and severity, during and after pregnancy. Healthcare providers have the potential to identify and support women who experience domestic violence. We sought to investigate the knowledge and perceptions of domestic violence among doctors who provide routine antenatal and postnatal care at healthcare facilities in Pakistan...
September 22, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28938242/clinical-data-warehouse-an-effective-tool-to-create-intelligence-in-disease-management
#16
Mahtab Karami, Azin Rahimi
Clinical business intelligence tools such as clinical data warehouse enable health care organizations to objectively assess the disease management programs that affect the quality of patients' life and well-being in public. The purpose of these programs is to reduce disease occurrence, improve patient care, and decrease health care costs. Therefore, applying clinical data warehouse can be effective in generating useful information about aspects of patient care to facilitate budgeting, planning, research, process improvement, external reporting, benchmarking, and trend analysis, as well as to enable the decisions needed to prevent the progression or appearance of the illness aligning with maintaining the health of the population...
September 21, 2017: Health Care Manager
https://www.readbyqxmd.com/read/28937148/transition-from-paediatric-to-adult-ophthalmology-services-what-matters-most-to-young-people-with-visual-impairment
#17
A O Robertson, V Tadić, J S Rahi
PurposeTo identify the views and experiences and thus the transition-related needs of young people with visual impairment (VI), so as to inform future practice and policies.Patients and methodsQualitative study of 17 young people aged 16-19 years (ie the conventional transition age threshold) with VI (best-corrected acuity logMAR worse than 0.48) and without additional impairments, drawn from a sampling frame of paediatric ophthalmology patients attending Great Ormond Street Hospital and Moorfields Eye Hospital (London, UK)...
September 22, 2017: Eye
https://www.readbyqxmd.com/read/28937004/suicide-in-india-part-perceptions-partial-insights-and-inadequate-solutions
#18
K S Jacob
Suicide is a complex phenomenon, often linked to environment. Despite the identification of many social, cultural, economic and political correlates and risk factors, psychiatry continues to argue for curative solutions based on the reductionistic biomedical model, rather than support public health measures to manage the larger sociocultural, economic and political context. While psychiatry and curative medicine help many people, survival of the human body is best explained by the materialist explanation that locates the variation in health and longevity to tangible resources...
May 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28935873/whole-genome-sequencing-molecular-typing-and-in-vivo-virulence-of-oxa-48-producing-escherichia-coli-isolates-including-st131-h30-rx-h22-and-h41-subclones
#19
María de Toro, Javier Fernández, Vanesa García, Azucena Mora, Jorge Blanco, Fernando de la Cruz, M Rosario Rodicio
Carbapenem-resistant Enterobacteriaceae, including the increasingly reported OXA-48 Escherichia coli producers, are an emerging public health threat worldwide. Due to their alarming detection in our healthcare setting and their possible presence in the community, seven OXA-48-producing, extraintestinal pathogenic E. coli were analysed by whole genome sequencing as well as conventional tools, and tested for in vivo virulence. As a result, five E. coli OXA-48-producing subclones were detected (O25:H4-ST131/PST43-fimH30-virotype E; O25:H4-ST131/PST9-fimH22-virotype D5, O16:H5-ST131/PST506-fimH41; O25:H5-ST83/PST207 and O9:H25-ST58/PST24)...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28935231/pandemic-legislation-in-the-european-union-fit-for-purpose-the-need-for-a-systematic-comparison-of-national-laws
#20
Elizabeth M Speakman, Scott Burris, Richard Coker
Sound governance is central to effective pandemic management. Key international legal instruments governing pandemic management in the European Union (EU): the International Health Regulations (2005) and Decision 1082/13 require EU Member States to develop national plans and invite them to establish national legal frameworks to support compliance with this international legislation. Although Member States may design the legal framework as they choose, the strongest instrument of pandemic governance is national legislation...
September 1, 2017: Health Policy
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