keyword
https://read.qxmd.com/read/38632053/spot-urinary-sodium-guided-titration-of-intravenous-diuretic-therapy-in-acute-heart-failure-a-pilot-randomised-controlled-trial
#1
JOURNAL ARTICLE
Maryam Khorramshahi Bayat, Wandy Chan, Karen Hay, Scott McKenzie, Polash Adhikari, Gavin Fincher, Faye Jordan, Isuru Ranasinghe
BACKGROUND: Spot urinary sodium concentration (UNa) is advocated in guidelines to assess diuretic response and titrate dosage in acute heart failure (AHF). However, no randomised controlled trial data exists to support this approach. We performed a prospective pilot trial to investigate the feasibility of this approach. METHODS: 60 patients with AHF (n = 30 in each arm) were randomly assigned to titration of loop diuretics for the first 48 hours of admission according to UNa levels (intervention arm) or based on clinical signs and symptoms of congestion (standard care arm)...
April 17, 2024: European Heart Journal. Quality of Care & Clinical Outcomes
https://read.qxmd.com/read/38589262/combination-of-diuretics-for-acute-heart-failure-a-protocol-for-a-systematic-review-of-randomised-clinical-trials-with-network-meta-analysis-and-trial-sequential-analysis
#2
JOURNAL ARTICLE
Nihal Nahiz, Jasmin Dam Lukoschewitz, Ekim Seven, Nora Olsen El Caidi, Jens Dahlgaard Hove, Janus Jakobsen, Johannes Grand
INTRODUCTION: Acute heart failure (AHF) is a critical, costly condition with high mortality rates, affecting millions annually. Despite advances in cardiovascular care, AHF treatment lacks robust evidence. AHF commonly manifests with sudden heart failure symptoms such as pulmonary congestion, and the pathophysiology involves fluid overload. Initial treatment is based on intravenous diuretics typically, but the optimal combination of drugs remains uncertain. METHODS AND ANALYSIS: We will systematically review randomised controlled trials enrolling patients with AHF and volume overload undergoing in-hospital diuretic treatment...
April 8, 2024: BMJ Open
https://read.qxmd.com/read/38581454/neighborhood-socioeconomic-disadvantages-associated-with-increased-rates-of-revisions-readmissions-and-complications-after-total-joint-arthroplasty
#3
JOURNAL ARTICLE
Sandeep S Bains, Jeremy A Dubin, Daniel Hameed, Scott Douglas, Ruby Gilmor, Christopher G Salib, James Nace, Michael Mont, Ronald E Delanois
INTRODUCTION: Low socioeconomic status based on neighborhood of residence has been suggested to be associated with poor outcomes after total joint arthroplasty (TJA). The area deprivation index (ADI) is a scale that ranks (zero to 100) neighborhoods by increasing socioeconomic disadvantage and accounts for median income, housing type, and family structure. We sought to examine the potential differences between high (national median ADI = 47) and low ADI among TJA recipients at a single institution...
April 6, 2024: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/38574807/outcomes-of-patients-with-acute-type-b-aortic-dissection-and-high-risk-features
#4
JOURNAL ARTICLE
Jonathan R Krebs, Amanda C Filiberto, Brian Fazzone, Christopher R Jacobs, Erik M Anderson, Zain Shahid, Martin Back, Gilbert R Upchurch, Michol Cooper
BACKGROUND: Recently the SVS and STS published contemporary guidelines clearly defining complicated vs uncomplicated acute type B aortic dissections (TBADs) with an additional high-risk grouping. Few studies have evaluated outcomes associated with "high-risk" TBADs. The objective of this study was to assess differences in demographics, clinical presentation, symptom onset, and outcomes in high-risk patients that underwent either thoracic endovascular aortic repair (TEVAR) or best medical management for acute TBAD compared to those with complicated and uncomplicated acute TBAD...
April 2, 2024: Annals of Vascular Surgery
https://read.qxmd.com/read/38571866/risk-factors-for-unexpected-admission-following-lumbar-spine-laminectomy-a-national-database-study
#5
JOURNAL ARTICLE
John M Tarazi, Petros Koutsogiannis, Emma K Humphrey, Nabil Z Khan, Michael Katsigiorgis, Gus Katsigiorgis, Randy M Cohn
Introduction Laminectomy is one of the most common orthopedic spine surgeries performed in the United States. Compared to other spine operations such as fusions, laminectomies in isolation are of lower morbidity. However, complications may arise that result in readmission to an inpatient healthcare facility. The purpose of this study is to identify the demographics and risk factors associated with unplanned 30-day readmission following a laminectomy. Methods The American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was queried for patients who underwent a laminectomy procedure from 2015 to 2019 using CPT code 63030...
March 2024: Curēus
https://read.qxmd.com/read/38545901/the-impact-on-thirty-day-readmissions-for-patients-hospitalized-for-acute-exacerbations-of-chronic-obstructive-pulmonary-disease-admitted-to-an-observation-unit-versus-an-inpatient-medical-unit-a-retrospective-observational-study
#6
JOURNAL ARTICLE
Jacob Bell, Steven Lim, Takahisa Mikami, Jeeyune Bahk, Stephen Argiro, David Steiger
OBJECTIVES: We aimed to evaluate the utility of an Observation Unit (OU) in management of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) and to identify the clinical characteristics of patients readmitted within 30-days for AECOPD following index admission to the OU or inpatient floor from the OU. METHODS: This is a retrospective observational study of patients admitted from January to December 2017 for AECOPD to an OU in an urban-based tertiary care hospital...
2024: Chronic Respiratory Disease
https://read.qxmd.com/read/38466983/machine-learning-model-for-readmission-prediction-of-patients-with-heart-failure-based-on-electronic-health-records-protocol-for-a-quasi-experimental-study-for-impact-assessment
#7
JOURNAL ARTICLE
Monika Nair, Lina E Lundgren, Amira Soliman, Petra Dryselius, Ebba Fogelberg, Marcus Petersson, Omar Hamed, Miltiadis Triantafyllou, Jens Nygren
BACKGROUND: Care for patients with heart failure (HF) causes a substantial load on health care systems where a prominent challenge is the elevated rate of readmissions within 30 days following initial discharge. Clinical professionals face high levels of uncertainty and subjectivity in the decision-making process on the optimal timing of discharge. Unwanted hospital stays generate costs and cause stress to patients and potentially have an impact on care outcomes. Recent studies have aimed to mitigate the uncertainty by developing and testing risk assessment tools and predictive models to identify patients at risk of readmission, often using novel methods such as machine learning (ML)...
March 11, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38430084/remote-dielectric-sensing-before-and-after-discharge-in-patients-with-adhf-the-reds-safe-hf-trial
#8
JOURNAL ARTICLE
Jesus Alvarez-Garcia, Anuradha Lala, Mercedes Rivas-Lasarte, Clemencia De Rueda, Danielle Brunjes, Sara Lozano-Jimenez, Cristina Garcia-Sebastian, Sumeet Mitter, Paloma Remior, Marta Jimenez-Blanco Bravo, Susana Del Prado, Maya Barghash, Eduardo González-Ferrer, Jennifer Ullman, Marta Cobo, Javier Segovia-Cubero, José Luis Zamorano, Sean P Pinney, Donna Mancini
BACKGROUND: Incomplete treatment of congestion often leads to worsening heart failure (HF). The remote dielectric sensing (ReDS) system is an electromagnetic energy-based technology that accurately quantifies changes in lung fluid concentration noninvasively. OBJECTIVES: This study sought to assess whether an ReDS-guided strategy during acutely decompensated HF hospitalization is superior to routine care for improving outcomes at 1 month postdischarge. METHODS: ReDS-SAFE HF (Use of ReDS for a SAFE discharge in patients with acute Heart Failure) was an investigator-initiated, multicenter, single-blind, randomized, proof-of-concept trial in which 100 patients were randomized to a routine care strategy, with discharge criteria based on current clinical practice, or an ReDS-guided decongestion strategy, with discharge criteria requiring an ReDS value of ≤35%...
February 12, 2024: JACC. Heart Failure
https://read.qxmd.com/read/38379137/success-in-heart-failure-an-investigation-of-heart-failure-readmission-rates-and-medication-regimen-optimization
#9
JOURNAL ARTICLE
Dominic Bracken, Sarah Wagner-Dallas, Destiny Branum
In May 2022, the American College of Cardiology updated their guideline-directed medical therapy for congestive heart failure (CHF) to include four pillars of therapy. These pillars aim to better control patients with heart failure (HF) and reduce the incidence of hospitalization by including an evidence-based beta-blocker, an angiotensin-converting enzyme inhibitor/ angiotensin receptor blocker/angiotensin receptor/ neprilysin inhibitor, a mineralocorticoid receptor antagonist, and newly recommended sodium glucose cotransporter 2-inhibitors...
March 1, 2024: Senior Care Pharmacist
https://read.qxmd.com/read/38315675/assessing-the-excess-costs-of-the-in-hospital-adverse-events-covered-by-the-ahrq-s-patient-safety-indicators-in-switzerland
#10
JOURNAL ARTICLE
Alice Giese, Rasheda Khanam, Son Nghiem, Anthony Staines, Thomas Rosemann, Stefan Boes, Michael M Havranek
There currently exists no comprehensive and up-to date overview on the financial impact of the different adverse events covered by the Patient Safety Indicators (PSIs) from the Agency for Healthcare Research and Quality. We conducted a retrospective case-control study using propensity score matching on a national administrative data set of 1 million inpatients in Switzerland to compare excess costs associated with 16 different adverse events both individually and on a nationally aggregated level. After matching 8,986 cases with adverse events across the investigated PSIs to 26,931 controls, we used regression analyses to determine the excess costs associated with the adverse events and to control for other cost-related influences...
2024: PloS One
https://read.qxmd.com/read/38252358/predictors-of-mortality-in-heart-failure-patients-with-reduced-or-mildly-reduced-ejection-fraction-the-casablanca-hf-study
#11
JOURNAL ARTICLE
Abdessamad Couissi, Meryem Haboub, Siyam Hamady, Taha Ettachfini, Rachida Habbal
BACKGROUND: Heart failure (HF) poses a significant public health challenge throughout the world and Morocco. Our objective was to delineate the epidemiological characteristics of Moroccan patients living with chronic heart failure and to identify prognostic factors correlated with CHF mortality. RESULTS: A total of 1344 patients participated in this study, with survival rates at 3, 6, and 10 years recorded at 75.2%, 60%, and 34%, respectively. During the follow-up, 886 patients succumbed, representing a mortality rate of 65...
January 22, 2024: Egyptian Heart Journal: EHJ
https://read.qxmd.com/read/38204501/diuretic-strategies-in-acute-decompensated-heart-failure-a-narrative-review
#12
REVIEW
Ben J Wilson, Duane Bates
BACKGROUND: Heart failure is a common condition with considerable associated costs, morbidity, and mortality. Patients often present to hospital with dyspnea and edema. Inadequate inpatient decongestion is an important contributor to high readmission rates. There is little evidence concerning diuresis to guide clinicians in caring for patients with acute decompensated heart failure. Contemporary diuretic strategies have been defined by expert opinion and older landmark clinical trials...
2024: Canadian Journal of Hospital Pharmacy
https://read.qxmd.com/read/38164707/comorbid-status-in-patients-with-osteomyelitis-is-associated-with-long-term-incidence-of-extremity-amputation
#13
JOURNAL ARTICLE
Brian M Schmidt, Toby P Keeney-Bonthrone, Armani M Hawes, Monika Karmakar, Lynn M Frydrych, Sandro K Cinti, Rodica Pop-Busui, Matthew J Delano
INTRODUCTION: Osteomyelitis is associated with significant morbidity, including amputation. There are limited data on long-term amputation rates following an osteomyelitis diagnosis. We sought to determine the incidence of amputation in patients with osteomyelitis over 2 years. RESEARCH DESIGN AND METHODS: Observational cohort study of 1186 inpatients with osteomyelitis between 2004 and 2015 and stratified by osteomyelitis location status to evaluate the impact on amputation, mortality rates, readmission data, and inpatient days...
December 12, 2023: BMJ Open Diabetes Research & Care
https://read.qxmd.com/read/38153724/national-trends-in-30-day-readmission-following-transoral-robotic-surgery-for-oropharyngeal-squamous-cell-carcinoma
#14
JOURNAL ARTICLE
Sarah C Nyirjesy, Hilary C McCrary, Songzhu Zhao, Ryan T Judd, Janice L Farlow, Nolan B Seim, Enver Ozer, Amit Agrawal, Matthew O Old, James W Rocco, Stephen Y Kang, Catherine T Haring
IMPORTANCE: As the incidence of oropharyngeal squamous cell carcinoma (OPSCC) continues to rise in the US, an increasing number of patients are being treated with transoral robotic surgery (TORS). Readmission following surgery can potentially delay initiation of adjuvant treatment and affect survival outcomes. OBJECTIVE: To identify risk factors for 30-day postoperative readmission in patients undergoing TORS for OPSCC. DESIGN, SETTING, AND PARTICIPANTS: This retrospective, population-based cohort study used data from the Nationwide Readmissions Database from 2010 to 2017...
December 28, 2023: JAMA Otolaryngology—Head & Neck Surgery
https://read.qxmd.com/read/38137728/prognostic-implication-of-intestinal-wall-edema-in-patients-with-aortic-stenosis-receiving-trans-catheter-aortic-valve-replacement
#15
JOURNAL ARTICLE
Kousuke Akao, Teruhiko Imamura, Shuhei Tanaka, Hiroshi Onoda, Ryuichi Ushijima, Mitsuo Sobajima, Nobuyuki Fukuda, Hiroshi Ueno, Koichiro Kinugawa
BACKGROUND: A recently proposed mechanism, the intestinal-cardiovascular relationship, serves as a framework to elucidate the interplay between these two systems. In our investigation, we assessed the prognostic implications of colon wall thickness, a marker correlated with intestinal congestion and dysfunction, in patients diagnosed with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). METHODS: Patients diagnosed with severe aortic stenosis who underwent TAVR at our institution during the period spanning 2015 to 2022 were retrospectively enrolled...
December 13, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/38093471/effects-of-a-collaborative-health-management-model-on-people%C3%A2-with-congestive-heart-failure-a-systematic-review-and-meta-analysis
#16
REVIEW
Chih Wen Chen, Mei-Chen Lee, Shu-Fang Vivienne Wu
AIM: To determine the effects of collaborative health management of congestive heart failure through the rigorous evaluation and extraction of evidence. BACKGROUND: Over the past two decades, cardiovascular disease has been the leading cause of death worldwide. Multidisciplinary team intervention for congestive heart failure has increased with population ageing and congestive heart failure incidence rate as well as cost of care. However, the effectiveness and feasibility of collaborative health management need to be explored...
December 13, 2023: Journal of Advanced Nursing
https://read.qxmd.com/read/38075471/safety-and-outcomes-of-hip-and-knee-replacement-surgery-in-liver-transplant-recipients
#17
JOURNAL ARTICLE
Mohamed Ahmed, Abdelrhman Abumoawad, Fouad Jaber, Hebatullah Elsafy, Saqr Alsakarneh, Laith Al Momani, Alisa Likhitsup, John H Helzberg
BACKGROUND: Liver transplant (LT) is becoming increasingly common with improved life expectancy. Joint replacement is usually a safe procedure; however, its safety in LT recipients remains understudied. AIM: To evaluate the mortality, outcome, and 90-d readmission rate in LT patients undergoing hip and knee replacement surgery. METHODS: Patients with history of LT who underwent hip and knee replacement surgery between 2016 and 2019 were identified using the National Readmission Database...
November 18, 2023: World Journal of Orthopedics
https://read.qxmd.com/read/38065589/heart-failure-management-at-home-a-non-randomised-prospective-case-controlled-trial-heman-at-home
#18
JOURNAL ARTICLE
Justin Helberg, Daniel Bensimhon, Vasili Katsadouros, Michelle Schmerge, Heather Smith, Kelly Peck, Kim Williams, William Winfrey, Ankit Nanavati, Jon Knapp, Monica Schmidt, Lisa Curran, Megan McCarthy, Mark Sawulski, Lawrence Harbrecht, Idalys Santos, Ellie Masoudi, Nischal Narendra
BACKGROUND/OBJECTIVES: Heart failure (HF) is a growing clinical and economic burden for patients and health systems. The COVID-19 pandemic has led to avoidance and delay in care, resulting in increased morbidity and mortality among many patients with HF. The increasing burden of HF during the COVID-19 pandemic led us to evaluate the quality and safety of the Hospital at Home (HAH) for patients presenting to their community providers or emergency department (ED) with symptoms of acute on chronic HF (CHF) requiring admission...
December 7, 2023: Open Heart
https://read.qxmd.com/read/38062751/fragmentation-of-care-after-geriatric-trauma-a-nationwide-analysis-of-outcomes-and-predictors
#19
JOURNAL ARTICLE
Shekhar Gogna, Bardiya Zangbar, Aryan Rafieezadeh, Kamil Hanna, Ilya Shnaydman, Jorge Con, Matthew Bronstein, Joshua Klein, Kartik Prabhakaran
The health care system for the elderly is fragmented, that is worsened when readmission occurs to different hospitals. There is limited investigation into the impact of fragmentation on geriatric trauma patient outcomes. The aim of this study was to compare the outcomes following readmissions after geriatric trauma. The Nationwide Readmissions Database (2016-2017) was queried for elderly trauma patients (aged ≥65 years) readmitted due to any cause. Patients were divided into 2 groups according to readmission: index vs non-index hospital...
December 7, 2023: American Surgeon
https://read.qxmd.com/read/38052347/sex-differences-in-myocarditis-hospitalizations-rates-outcomes-and-hospital-characteristics-in-the-national-readmission-database
#20
REVIEW
Ahmed M Elzanaty, Amro Aglan, Mohammed Yassen, Rachel Royfman, Ahmed Maraey, Mahmoud Khalil, Meghana Ranabothu, Shikha Lakhani, Andrew Waack, Eman Elsheikh, Ehab Eltahawy
Inflammation of the myocardium, or myocarditis, presents with varied severity, from mild to life-threatening such as cardiogenic shock or ventricular tachycardia storm. Existing data on sex-related differences in its presentation and outcomes are scarce. Using the Nationwide Readmission Database (2016-2019), we identified myocarditis hospitalizations and stratified them according to sex to either males or females. Multivariable regression analyses were used to determine the association between sex and myocarditis outcomes...
December 3, 2023: Current Problems in Cardiology
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