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https://www.readbyqxmd.com/read/28429032/obstructive-sleep-apnoea-and-type-2-diabetes-mellitus-are-they-connected
#1
Yingjuan Mok, Chee Wei Tan, Hang Siang Wong, Choon How How, Kah Leong Alvin Tan, Pon Poh Hsu
Obstructive sleep apnoea (OSA), a sleep-related breathing condition, is diagnosed based on a patient's apnoea-hypopnea index from a sleep study, and the presence or absence of symptoms. Diabetes mellitus (DM) and OSA share a significant common risk factor, obesity, with all three conditions contributing to the risk of developing cardiovascular diseases. The pathophysiological links between OSA and DM are still unclear, but intermittent hypoxia may be an important mechanism. More awareness of the possible link between OSA and DM is needed, given their increasing prevalence locally and worldwide...
April 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28422119/current-lifestyle-factors-that-increase-risk-of-t2dm-in-china
#2
REVIEW
N Zhang, S M Du, G S Ma
The Report on the Status of Nutrition and Chronic Diseases of Chinese residents (2015) indicated that the prevalence of diabetes was 9.7% among adults aged ⩾18 years, which markedly increased from 2.6% in 2002 within 10 years. In addition to the social economic factors, transitions in food consumption, behavioral and lifestyle playing the important roles in the fast increase of type 2 diabetes mellitus (T2DM). In 2010-2012, the cereal food consumption of Chinese residents was 337 g/d, vegetables consumption 269 g/d, fruit consumption 41 g/d, legume and legume products 11 g/d, dairy and dairy products consumption 25 g/d, meat consumption 90 g/d, edible oil consumption 42 g/d and dietary fiber 10...
April 19, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28413931/glucose-variations-and-activity-are-strongly-coupled-in-sleep-and-wake-in-young-adults-with-type-1-diabetes
#3
Sarah S Farabi, David W Carley, Lauretta Quinn
BACKGROUND: Glucose variations are common throughout sleep and wakefulness in people with type 1 diabetes mellitus (T1DM). The objective of this investigation was to characterize the time-varying coupling between glucose and unstructured physical activity over a 60-hr period in young adults with T1DM. The hypothesis was that coupling would differ during sleep versus wakefulness and would exhibit circadian variations. METHOD: Young adults with T1DM treated with an insulin pump participated in the study...
May 2017: Biological Research for Nursing
https://www.readbyqxmd.com/read/28407021/analysis-of-the-prevalence-and-associated-factors-of-overactive-bladder-in-adult-korean-men
#4
So Young Kim, Woojin Bang, Hyo Geun Choi
Overactive bladder (OAB) is a prevalent condition characterized by lower urinary tract symptoms (LUTS). Age, education, income, marital status, sleep, and emotional problems have been associated with OAB; however, conflicting results exist. The present study was conducted to estimate the prevalence of OAB and comprehensively analyze its associated factors in a large cross-sectional, population-based study. The data of 94,554 participants aged 19-107 were analyzed from the Korean Community Health Survey (KCHS) of 2012...
2017: PloS One
https://www.readbyqxmd.com/read/28393727/platelet-indices-in-obstructive-sleep-apnea-the-role-of-mean-platelet-volume-platelet-distribution-widht-and-plateletcrit
#5
Yılmaz Bülbül, Esra Aydın Özgür, Asım Örem
Introduction: Because studies report controversial findings of mean platelet volume (MPV) and platelet distribution width (PDW), we aimed to investigate platelet indices in patients with obstructive sleep apnea (OSA). Materials and Methods: One hundred seventy three patients with OSA and 43 control subjects included in analyses. Patients with an apnea-hypopnea index (AHI) ≥ 5 were considered to have OSA and an AHI < 5 were considered as control. Platelet indices (MPV, PDW, plateletcrit) were obtained from routine analysis of blood samples using an automated blood cell counter...
September 2016: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/28387058/impact-of-empagliflozin-on-blood-pressure-in-dipper-and-non-dipper-patients-with-type-2-diabetes-mellitus-and-hypertension
#6
Robert Chilton, Ilkka Tikkanen, Uwe Hehnke, Hans J Woerle, Odd Erik Johansen
In the EMPA-REG BP® trial, empagliflozin significantly reduced systolic and diastolic blood pressure (SBP and DBP) versus placebo at week 12 in patients with type 2 diabetes mellitus (T2DM) and hypertension. In a post-hoc analysis, we assessed the effect of empagliflozin on SBP and DBP using 24-hour ambulatory BP monitoring in patients categorized as dippers (sleep-time mean SBP ≤90% of awake-time mean; n = 417) or non-dippers (sleep-time mean SBP >90% of awake-time mean; n = 350). In dippers, adjusted mean (SE) changes from baseline in mean 24-hour SBP (mmHg) at week 12 were -0...
April 6, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28384165/ramadan-fasting-in-saudi-arabia-is-associated-with-altered-expression-of-clock-dusp-and-il-1alpha-genes-as-well-as-changes-in-cardiometabolic-risk-factors
#7
Ghada M A Ajabnoor, Suhad Bahijri, Noor Ahmad Shaik, Anwar Borai, Aliaa A Alamoudi, Jumana Y Al-Aama, George P Chrousos
BACKGROUND: During the fasting month of Ramadan, practicing Saudis develop severe disturbances in sleeping and feeding patterns. Concomitantly, cortisol circadian rhythm is abolished, diurnal cortisol levels are elevated and circulating levels of several adipokines are altered favouring insulin resistance. AIM: To examine changes in the expression of CLOCK and glucocorticoid-controlled genes, such as DUSP1 and IL-1α in Saudi adults before and during Ramadan, and to investigate possible associations with selected cardiometabolic risk factors...
2017: PloS One
https://www.readbyqxmd.com/read/28366153/-platelet-indices-in-obstructive-sleep-apnea-the-role-of-mean-platelet-volume-platelet-distribution-widht-and-plateletcrit
#8
Yılmaz Bülbül, Esra Aydın Özgür, Asım Örem
Introduction: Because studies report controversial findings of mean platelet volume (MPV) and platelet distribution width (PDW), we aimed to investigate platelet indices in patients with obstructive sleep apnea (OSA). Materials and Methods: One hundred seventy three patients with OSA and 43 control subjects included in analyses. Patients with an apnea-hypopnea index (AHI) ≥ 5 were considered to have OSA and an AHI < 5 were considered as control. Platelet indices (MPV, PDW, plateletcrit) were obtained from routine analysis of blood samples using an automated blood cell counter...
September 2016: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/28364489/sleep-quality-and-nocturnal-sleep-duration-in-pregnancy-and-risk-of-gestational-diabetes-mellitus
#9
Shirong Cai, Sara Tan, Peter D Gluckman, Keith M Godfrey, Seang-Mei Saw, Oon Hoe Teoh, Yap-Seng Chong, Michael J Meaney, Michael S Kramer, Joshua J Gooley
Study Objectives: To examine the influence of maternal sleep quality and nocturnal sleep duration on risk of gestational diabetes mellitus (GDM) in a multiethnic Asian population. Methods: A cohort of 686 women (376 Chinese, 186 Malay, and 124 Indian) with a singleton pregnancy attended a clinic visit at 26-28 weeks of gestation as part of the Growing Up in Singapore Towards healthy Outcomes mother-offspring cohort study. Self-reported sleep quality and sleep duration were assessed using the Pittsburgh Sleep Quality Index (PSQI)...
February 1, 2017: Sleep
https://www.readbyqxmd.com/read/28352282/poor-sleep-quality-is-associated-with-dawn-phenomenon-and-impaired-circadian-clock-gene-expression-in-subjects-with-type-2-diabetes-mellitus
#10
Yuxin Huang, Haidong Wang, Yuan Li, Xiaoming Tao, Jiao Sun
Aims. We investigated whether poor sleep quality is associated with both dawn phenomenon and impaired circadian clock gene expression in subjects with diabetes. Methods. 81 subjects with diabetes on continuous glucose monitoring were divided into two groups according to the Pittsburgh Sleep Quality Index. The magnitude of dawn phenomenon was quantified by its increment from nocturnal nadir to prebreakfast. Peripheral leucocytes were sampled from 81 subjects with diabetes and 28 normal controls at 09:00. Transcript levels of circadian clock genes (BMAL1, PER1, PER2, and PER3) were determined by real-time quantitative polymerase chain reaction...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28338434/coexistence-of-obstructive-sleep-apnea-worsens-the-overall-outcome-of-intracranial-aneurysm-a-pioneer-study
#11
Shyamal C Bir, Anil Nanda, Hugo Cuellar, Hai Sun, Bharat Guthikonda, Cesar Liendo, Alireza Minagar, Oleg Y Chernyshev
OBJECTIVE Obstructive sleep apnea (OSA) is associated with the progression of abdominal and thoracic aortic aneurysms. However, the role of OSA in the overall outcome of intracranial aneurysms (IAs) has not yet been established. Authors of this report investigated the role of OSA in the overall outcome of IAs. METHODS Radiological and clinical data on patients (from 2010 through 2015) with confirmed IA were retrospectively reviewed. Significant differences between the OSA and non-OSA groups were determined using a chi-square test...
March 21, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28287278/carotid-intima-media-thickness-is-not-associated-with-homocysteine-and-vitamin-d-levels-in-obstructive-sleep-apnea
#12
Katarína Klobučníková, Pavel Šiarnik, Monika Siváková, Helena Wágnerová, Imrich Mucska, Branislav Kollár, Peter Turčáni
Obstructive sleep apnea syndrome (OSA) is associated with increased vascular morbidity. Accelerated atherosclerosis might be one of the most important mechanisms linking OSA with the development of vascular disorders. Homocysteine (HCY) and vitamin D has been associated with atherogenesis. The aim of this study was to assess a possible association between the levels of HCY and vitamin D and the carotid intima-media thickness (cIMT), which is a known marker for subclinical atherosclerosis in patients with OSA...
March 13, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28285988/essential-parameters-and-risk-factors-of-the-patients-for-diabetes-care-and-treatment
#13
Abdulbari Bener, Fatma Ela Keskin, Eda M Kurtulus, Mustafa Guzel, Elif I Çekirdekçi, Pınar Kadıoğlu, Dildar Konukoğlu, Mustafa Öztürk
AIM: The aim was to explore the association between Type 2 Diabetes Mellitus [T2DM] treatment satisfactions of patients regarding their socio-economic, life-style, history medication and clinical outcome in a Turkish population SUBJECT AND METHODS: A cross-sectional study conducted from February 2016 to September 2016. Of the total 1500 diabetic patients approached, 1094 (72.9%) gave their consent. Data analysis included, sociodemographic, serum lipid profiles (LDL, HDL), calcium, uric acid, blood pressure and glycated hemoglobin (HbA1c) at baseline and after six months...
March 6, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28285739/neuropsychiatric-comorbidities-in-adults-with-phenylketonuria-a-retrospective-cohort-study
#14
Deborah A Bilder, Joyce A Kobori, Jessica L Cohen-Pfeffer, Erin M Johnson, Elaina R Jurecki, Mitzie L Grant
Adults with phenylketonuria (PKU) may experience neurologic and psychiatric disorders, including intellectual disability, anxiety, depression, and neurocognitive dysfunction. Identifying the prevalence and prevalence ratios of these conditions will inform clinical treatment. This nested, case-controlled study used International Classification of Diseases, Ninth Revision (ICD-9) codes from the MarketScan® insurance claims databases from 2006 to 2012 and healthcare claims data for US-based employer and government-sponsored health plans...
March 6, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28281834/association-of-sleep-disordered-breathing-with-diabetes-associated-kidney-disease
#15
Stefan Stadler, Tanja Zimmermann, Franziska Franke, Myriam Rheinberger, Iris M Heid, Carsten A Böger, Michael Arzt
INTRODUCTION: Diabetes-associated kidney disease is characterized by impairment of renal function and albuminuria. The aim of the present study was to assess whether sleep-disordered breathing is associated with decreased estimated glomerular filtration rate or increased urine-albumin-to-creatinine-ratio independently from known modulators of diabetes-associated kidney disease. MATERIAL AND METHODS: Estimated glomerular filtration rate and urine-albumin-to-creatinine-ratio were determined in the baseline survey of the DIACORE-SDB substudy, a prospectively planned study of Diabetes mellitus 2 patients...
March 27, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28274539/the-clinical-impact-of-major-comorbidities-on-idiopathic-pulmonary-fibrosis
#16
REVIEW
Atsushi Suzuki, Yasuhiro Kondoh
Idiopathic pulmonary fibrosis (IPF) is a progressive and devastating disease with a median survival time of 2-3 years after diagnosis. Patients with IPF exhibit distinct patterns of disease progression, and some patients display a more rapidly progressive clinical course. The clinical course of IPF may also include periods of acute deterioration, which are termed acute exacerbations. Patients with IPF frequently experience various comorbidities, such as pulmonary infection, emphysema, pulmonary hypertension, lung cancer, gastroesophageal reflux, cardiovascular disease, diabetes mellitus, and obstructive sleep apnea...
March 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/28273173/relationships-between-lifestyle-patterns-and-cardio-renal-metabolic-parameters-in-patients-with-type-2-diabetes-mellitus-a-cross-sectional-study
#17
Takeshi Ogihara, Tomoya Mita, Yusuke Osonoi, Takeshi Osonoi, Miyoko Saito, Atsuko Tamasawa, Shiho Nakayama, Yuki Someya, Hidenori Ishida, Masahiko Gosho, Akio Kanazawa, Hirotaka Watada
INTRODUCTION: While individuals tend to show accumulation of certain lifestyle patterns, the effect of such patterns in real daily life on cardio-renal-metabolic parameters remains largely unknown. This study aimed to assess clustering of lifestyle patterns and investigate the relationships between such patterns and cardio-renal-metabolic parameters. PARTICIPANTS AND METHODS: The study participants were 726 Japanese type 2 diabetes mellitus (T2DM) outpatients free of history of cardiovascular diseases...
2017: PloS One
https://www.readbyqxmd.com/read/28270889/relationships-among-conventional-cardiovascular-risk-factors-and-lifestyle-habits-with-arterial-stiffness-in-type-2-diabetic-patients
#18
Misako Hamamura, Tomoya Mita, Yusuke Osonoi, Takeshi Osonoi, Miyoko Saito, Atsuko Tamasawa, Shiho Nakayama, Yuki Someya, Hidenori Ishida, Masahiko Gosho, Akio Kanazawa, Hirotaka Watada
BACKGROUND: While conventional cardiovascular risk factors and certain lifestyle habits are associated with arterial stiffness in patients with type 2 diabetes mellitus (T2DM), it is still unknown whether they are actually associated with arterial stiffness even after adjustment for conventional cardiovascular risk factors and lifestyle habits. The aim of this study was to identify variables that are associated with brachial-ankle pulse wave velocity (baPWV). METHODS: The study participants comprised 724 Japanese T2DM outpatients free of history of cardiovascular diseases...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28254339/obstructive-sleep-apnea-epidemiology-and-portuguese-patients-profile
#19
A P Rodrigues, P Pinto, B Nunes, C Bárbara
INTRODUCTION: Obstructive Sleep Apnea (OSA) is characterized by recurrent episodes of apnea and hypopnea, secondary to collapse of the upper airways during sleep. OSA is frequently associated to cardiovascular complications. In Portugal, its magnitude is unknown. METHODS: In 2014 a cross-sectional study was performed using the Portuguese General Practitioner (GP) Sentinel Network (Rede Médicos Sentinela). Participants GP reported all OSA cases diagnosed and registered in their lists of users on the 31 December 2013...
March 2017: Revista Portuguesa de Pneumologia
https://www.readbyqxmd.com/read/28254101/electroacupuncture-assisted-craniotomy-on-an-awake-patient
#20
Amritpal Sidhu, Trushna Murgahayah, Vairavan Narayanan, Hari Chandran, Vicknes Waran
Although acupuncture has existed for over 2000 years, its application as an anesthetic aid began in the 1950s in China. The first surgical procedure performed under acupuncture anesthesia was a tonsillectomy. Soon thereafter, major and minor surgical procedures took place with electroacupuncture alone providing the anesthesia. The procedures performed were diverse, ranging from cardiothoracic surgery to dental extractions. Usage of acupuncture anesthesia, specifically in neurosurgery, has been well documented in hospitals across China, especially in Beijing, dating back to the 1970s...
January 2017: Journal of Acupuncture and Meridian Studies
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