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Punctate inner choroiditis

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https://www.readbyqxmd.com/read/28513493/inflammatory-choroidal-neovascularization-in-indian-eyes-etiology-clinical-features-and-outcomes-to-anti-vascular-endothelial-growth-factor
#1
Rupak Roy, Kumar Saurabh, Aditya Bansal, Amitabh Kumar, Anindya Kishore Majumdar, Swakshyar Saumya Paul
BACKGROUND AND OBJECTIVES: The aim was to study the clinical profile of inflammatory choroidal neovascularization (CNV) and its treatment response to intravitreal bevacizumab or ranibizumab on pro re nata (PRN) basis in Indian eyes. MATERIALS AND METHODS: This was a retrospective case series of consecutive patients with inflammatory CNV treated with anti-vascular endothelial growth factor (anti-VEGF) in a tertiary eye care center in Eastern India between 2009 and 2014...
April 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28424992/intravitreal-anti-vegf-treatment-for-choroidal-neovascularization-secondary-to-punctate-inner-choroidopathy
#2
T Barth, F Zeman, H Helbig, M-A Gamulescu
PURPOSE: To assess the outcome of patients with choroidal neovascularization (CNV) secondary to punctate inner choroidopathy (PIC) receiving intravitreal anti-VEGF (vascular endothelial growth factor) injections. METHODS: Sixteen eyes of 16 patients diagnosed with CNV secondary to PIC were retrospectively assessed. RESULTS: Eleven women and five men with a mean age of 35 years (SD 11, range 16-56 years) received intravitreal anti-VEGF for PIC-related CNV...
April 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28297030/how-to-differentiate-myopic-choroidal-neovascularization-idiopathic-multifocal-choroiditis-and-punctate-inner-choroidopathy-using-clinical-and-multimodal-imaging-findings
#3
Rosa Dolz-Marco, Howard F Fine, K Bailey Freund
No abstract text is available yet for this article.
March 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28253223/observation-and-clinical-pattern-in-patients-with-white-dot-syndromes-the-role-of-color-photography-in-monitoring-ocular-changes-in-long-term-observation
#4
Joanna Brydak-Godowska, Joanna Gołębiewska, Monika Turczyńska, Joanna Moneta-Wielgoś, Agnieszka Samsel, Piotr K Borkowski, Michał Ciszek, Agnieszka Płonecka-Rodzoch, Aleksandra Kużnik-Borkowska, Joanna Ciszewska, Elżbieta Makomaska-Szaroszyk, Lidia B Brydak, Dariusz Kęcik
BACKGROUND The aim of this study was to assess the clinical course and distinctive features of different white dot syndromes (WDS) in patients attending the Ophthalmology Department, Medical University of Warsaw in the years 1995-2015. MATERIAL AND METHODS Sixty-two (62) patients (43 females and 19 males), aged 18 to 77 years, referred with a WDS were included in this prospective study, with observation period ranging from 5 months to 16 years. All patients underwent a complete ophthalmological examination and multimodal imaging studies...
March 2, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28005676/en-face-optical-coherence-tomography-and-optical-coherence-tomography-angiography-of-multiple-evanescent-white-dot-syndrome-new-insights-into-pathogenesis
#5
MULTICENTER STUDY
Francesco Pichi, Sunil K Srvivastava, Saradha Chexal, Andrea Lembo, Luiz H Lima, Piergiorgio Neri, Andrea Saitta, Jay Chhablani, Thomas A Albini, Paolo Nucci, K Bailey Freund, Hyewon Chung, Careen Y Lowder, David Sarraf
PURPOSE: To localize the various levels of abnormalities in multiple evanescent white dot syndrome by comparing "en face" optical coherence tomography (OCT) and OCT angiography with various conventional imaging modalities. METHODS: In this retrospective case series, multimodal imaging was performed in 9 retinal centers on 36 patients with multiple evanescent white dot syndrome and included widefield fundus autofluorescence (FAF), fluorescein angiography (FA), and indocyanine green angiography, and B-scan and "en face" C-scan enhanced depth imaging and spectral domain OCT...
December 2016: Retina
https://www.readbyqxmd.com/read/27994812/idiopathic-multifocal-choroiditis
#6
REVIEW
Ali Tavallali, Lawrence A Yannuzzi
Idiopathic multifocal choroiditis (MFC) and/or punctate inner choroidopathy (PIC) describe a chronic progressive bilateral inflammatory chorioretinopathy that predominantly affect healthy myopic white women with no known associated systemic or ocular diseases. The principal sites of involvement are the retinal pigment epithelium (RPE) and outer retinal spaces; the choroid is not affected during the active phase of the disease. Idiopathic MFC with atrophy is a recently described variant. Although there is no generally accepted standard treatment, anti-inflammatory and anti-VEGF (vascular endothelial growth factor) agents are necessary in the acute stage to control the inflammation and choroidal neovascularization (CNV)...
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27977842/optical-coherence-tomography-angiography-for-detecting-choroidal-neovascularization-secondary-to-punctate-inner-choroidopathy
#7
Shintaro Nakao, Yoshihiro Kaizu, Yuji Oshima, Taiji Sakamoto, Tatsuro Ishibashi, Koh-Hei Sonoda
Punctate inner choroidopathy (PIC) is a relatively uncommon inflammatory multifocal chorioretinopathy that predominantly affects young, myopic women. Subfoveal choroidal neovascularization (CNV) often leads to rapid loss of sight. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) remain the existing gold standards for CNV diagnosis. However, these methods are invasive and time-consuming. Recently, optical coherence tomography angiography (OCTA) has been used more frequently as an adjunct to FA/ICGA...
December 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27751823/punctate-inner-choroidopathy-a-review
#8
REVIEW
Dana Ahnood, Savitha Madhusudhan, Marie D Tsaloumas, Nadia K Waheed, Pearse A Keane, Alastair K Denniston
Punctate inner choroidopathy (PIC), an idiopathic inflammatory multifocal chorioretinopathy that predominantly affects young myopic women, appears to be relatively rare, but there are limited data to support accurate estimates of prevalence, and it is likely that the condition is underdiagnosed. The etiological relationship between PIC and other conditions within the "white dot syndromes" group remains uncertain. We, like others, would suggest that PIC and multifocal choroiditis with panuveitis represent a single disease process that is modified by host factors (including host immunoregulation) to cause the range of clinical phenotypes seen...
March 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/27729795/combined-treatment-in-punctate-inner-choroidopathy
#9
Barbara Terelak-Borys, Katarzyna Zagajewska, Irmina Jankowska-Lech, Piotr Tesla, Iwona Grabska-Liberek
PURPOSE: The purpose of this study was to describe a combination treatment for choroidal neovascular (CNV) membrane, secondary to punctate inner choroidopathy (PIC). PATIENT AND METHODS: A 44-year-old female patient was diagnosed with PIC complicated by the development of recurrent juxtafoveal neovascular membrane. The treatment included a sequence of monotherapy regimens: systemic steroid therapy, photodynamic therapy, and intravitreal injections of vascular endothelial growth factor (VEGF) inhibitor (anti-VEGF)...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27555066/punctate-inner-choroidopathy-complicated-with-exudative-neurosensory-detachment-a-favourable-response-to-treatment-with-systemic-corticosteroids-and-intravitreal-ranibizumab
#10
M Roca, M Menezo, J M Ronchera, J M Esteban, B Roca
CASE REPORT: Punctate inner choroidopathy (PIC) is a variant of multifocal choroiditis that principally affects young and healthy women. A case of this condition is described in a woman who presented with a scotoma as the main complaint. Four months after the diagnosis of PIC, she developed an exudative neurosensory detachment associated with an active focus of juxtafoveal choroiditis. Finally, with systemic corticosteroids and intravitreal ranibizumab, she made excellent progress. DISCUSSION: Intravitreal ranibizumab, associated with systemic corticosteroids, may be an effective treatment for exudative neurosensory detachment complicating PIC...
August 20, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27552295/en-face-optical-coherence-tomography-and-optical-coherence-tomography-angiography-of-multiple-evanescent-white-dot-syndrome-new-insights-into-pathogenesis
#11
Francesco Pichi, Sunil K Srvivastava, Saradha Chexal, Andrea Lembo, Luiz H Lima, Piergiorgio Neri, Andrea Saitta, Jay Chhablani, Thomas A Albini, Paolo Nucci, K Bailey Freund, Hyewon Chung, Careen Y Lowder, David Sarraf
PURPOSE: To localize the various levels of abnormalities in multiple evanescent white dot syndrome by comparing "en face" optical coherence tomography (OCT) and OCT angiography with various conventional imaging modalities. METHODS: In this retrospective case series, multimodal imaging was performed in 9 retinal centers on 36 patients with multiple evanescent white dot syndrome and included widefield fundus autofluorescence (FAF), fluorescein angiography (FA), and indocyanine green angiography, and B-scan and "en face" C-scan enhanced depth imaging and spectral domain OCT...
August 22, 2016: Retina
https://www.readbyqxmd.com/read/27539089/choroidal-neovascularisation-on-optical-coherence-tomography-angiography-in-punctate-inner-choroidopathy-and-multifocal-choroiditis
#12
Ashleigh L Levison, Kimberly M Baynes, Careen Y Lowder, Peter K Kaiser, Sunil K Srivastava
PURPOSE: To describe the findings seen on optical coherence tomography angiography (OCTA) in patients with punctate inner choroidopathy (PIC) and multifocal choroiditis and panuveitis (MCP) complicated by choroidal neovascular membranes. METHODS: This was an Institutional Review Board-approved prospective, descriptive case series. 12 patients with PIC and MCP complicated by choroidal neovascularisation (CNV) were included. Each patient underwent slit-lamp examination by a uveitis specialist followed by conventional spectral domain OCT imaging of the macula...
May 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27375068/etiology-and-treatment-of-choroidal-neovascularization-in-pediatric-patients
#13
Teresa Barth, Florian Zeman, Horst Helbig, Isabel Oberacher-Velten
PURPOSE: To assess the etiology, clinical features, and outcome of choroidal neovascularization (CNV) in children. METHODS: We retrospectively assessed 10 eyes of 8 patients younger than 18 years diagnosed with CNV. The main clinical parameters included predisposing ocular pathologies, best-corrected visual acuity before and after treatment, characteristics of CNV, and treatment modalities. RESULTS: Two boys and 6 girls with CNV and a mean age of 13...
August 4, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/26955337/choroidal-neovascularization-associated-with-punctate-inner-choroidopathy-combination-of-intravitreal-anti-vegf-and-systemic-immunosuppressive-therapy
#14
Bettina Hohberger, Michael Rudolph, Antonio Bergua
PURPOSE: Choroidal neovascularization (CNV) associated with punctate inner choroidopathy (PIC) is a rare clinical entity, yet still a challenge for medical treatment. A case of a young myopic woman developing CNV secondary to unilateral PIC is presented. Clinical morphology, diagnostic procedure and follow-up are reported. CASE REPORT: A 29-year-old woman presented with multiple yellowish dots at the posterior pole. No other signs of inflammation could be seen. Angiography with fluorescein yielded hyperfluorescent signals in the affected areas with a diffuse leak, and SD-OCT showed a slightly elevated retinal pigment epithelial layer, consistent with the diagnosis of PIC...
September 2015: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/26171640/clinical-characteristics-of-inflammatory-choroidal-neovascularization-in-a-chinese-population
#15
Kunfang Wu, Xiongze Zhang, Yu Su, Yuying Ji, Chengguo Zuo, Meng Li, Feng Wen
PURPOSE: To describe demographic features and clinical and imaging characteristics of inflammatory choroidal neovascularization (CNV) in a Chinese population. METHODS: A retrospective case review of patients with CNV secondary to uveitis from 2002 to 2013. RESULTS: A total of 125 patients (150 eyes, 166 CNVs; bifocal CNVs in 16 eyes), 64% of whom were women, were reviewed. The mean age was 35.86 years. The proportions of patients with punctate inner choroidopathy (PIC), multifocal choroiditis (MFC), and Vogt-Koyanagi-Harada (VKH) were 50...
June 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/25970862/punctate-hyperfluorescent-spots-associated-with-polypoidal-choroidal-vasculopathy-on-indocyanine-green-angiography
#16
Hyesun Kim, Ji Hwan Lee, Kye Yoon Kwon, Suk Ho Byeon, Sung Chul Lee, Christopher Seungkyu Lee
BACKGROUND AND OBJECTIVE: To evaluate punctate hyperfluorescent spots on indocyanine green angiography (ICGA) in eyes with polypoidal choroidal vasculopathy (PCV). PATIENTS AND METHODS: Retrospective observation case series of 88 eyes of 81 patients (63 men and 18 women) analyzing fundus photography, fluorescein angiography, ICGA, and spectral-domain optical coherence tomography (OCT) findings at baseline. RESULTS: Seven patients (9%) had bilateral PCV lesions...
April 2015: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/25687028/focal-choroidal-excavation-in-multifocal-choroiditis-and-punctate-inner-choroidopathy
#17
COMMENT
Hyesun Kim, Se Joon Woo, Yong-Kyu Kim, Sung Chul Lee, Christopher Seungkyu Lee
No abstract text is available yet for this article.
July 2015: Ophthalmology
https://www.readbyqxmd.com/read/25631844/spectral-domain-optical-coherence-tomographic-features-of-choroidal-neovascular-membranes-in-multifocal-choroiditis-and-punctate-inner-choroidopathy
#18
Radgonde Amer, Ethan Priel, Michal Kramer
PURPOSE: To describe the spectral-domain optical coherence tomographic (SD-OCT) features of inflammatory choroidal neovascular membranes (iCNV) in multifocal choroiditis and punctate inner choroidopathy, and to compare them to those of the acute inflammatory lesions in the same underlying diseases. This is a retrospective, consecutive, observational case series. METHODS: Each patient underwent a comprehensive eye examination, fundus photography, and fluorescein angiography (FA) on the initial visit...
June 2015: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/25370399/unilateral-punctate-inner-choroidopathy-with-choroidal-neovascular-membrane-in-a-young-male
#19
Jyotirmay Biswas, Rajiv Raman, Deepak Bhojwani
No abstract text is available yet for this article.
September 2014: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/25302012/fundus-autofluorescence-features-in-the-inflammatory-maculopathies
#20
Cecilia S Lee, Aaron Y Lee, Farzin Forooghian, Chris S Bergstrom, Jiong Yan, Steven Yeh
PURPOSE: To describe the fundus autofluorescence (FAF) features of the inflammatory maculopathies and develop a quantification method for FAF analysis. METHODS: This is a retrospective, consecutive case series of patients with inflammatory maculopathies from two tertiary centers. The clinical findings, demographics, and FAF imaging characteristics were reviewed. Foveal autofluorescence (AF) was analyzed. Median and standard deviation (SD) of foveal AF intensity were measured...
2014: Clinical Ophthalmology
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