keyword
MENU ▼
Read by QxMD icon Read
search

Chirag Patel

keyword
https://www.readbyqxmd.com/read/28381511/a-single-demyelinating-attack-is-enough-to-limit-brain-growth-in-children
#1
Yael Hacohen, Chirag B Patel, Rogier Hintzen
No abstract text is available yet for this article.
April 5, 2017: Neurology
https://www.readbyqxmd.com/read/28291243/a-standard-database-for-drug-repositioning
#2
Adam S Brown, Chirag J Patel
Drug repositioning, the process of discovering, validating, and marketing previously approved drugs for new indications, is of growing interest to academia and industry due to reduced time and costs associated with repositioned drugs. Computational methods for repositioning are appealing because they putatively nominate the most promising candidate drugs for a given indication. Comparing the wide array of computational repositioning methods, however, is a challenge due to inconsistencies in method validation in the field...
March 14, 2017: Scientific Data
https://www.readbyqxmd.com/read/28251040/analytic-complexity-and-challenges-in-identifying-mixtures-of-exposures-associated-with-phenotypes-in-the-exposome-era
#3
REVIEW
Chirag J Patel
PURPOSE OF REVIEW: Mixtures, or combinations and interactions between multiple environmental exposures, are hypothesized to be causally linked with disease and health-related phenotypes. Established and emerging molecular measurement technologies to assay the exposome, the comprehensive battery of exposures encountered from birth to death, promise a new way of identifying mixtures in disease in the epidemiological setting. In this opinion, we describe the analytic complexity and challenges in identifying mixtures associated with phenotype and disease...
2017: Current Epidemiology Reports
https://www.readbyqxmd.com/read/28194614/the-exposome-research-paradigm-an-opportunity-to-understand-the-environmental-basis-for-human-health-and-disease
#4
REVIEW
Germaine M Buck Louis, Melissa M Smarr, Chirag J Patel
PURPOSE OF REVIEW: This paper presents an overview of the exposome research paradigm with particular application to understanding human reproduction and development and its implications for health across a lifespan. RECENT FINDINGS: The exposome research paradigm has generated considerable discussion about its feasibility and utility for delineating the impact of environmental exposures on human health. Early initiatives are underway, including smaller proof-of-principle studies and larger concerted efforts...
March 2017: Current Environmental Health Reports
https://www.readbyqxmd.com/read/28176476/recurrent-atypical-haemolytic-uraemic-syndrome-post-kidney-transplant-due-to-a-cd46-mutation-in-the-setting-of-smarcal1-mediated-inherited-kidney-disease
#5
REVIEW
Samuel Chan, Andrew J Mallett, Chirag Patel, Ross S Francis, David W Johnson, David W Mudge, Nicole M Isbel
Disorders in the regulation of the alternate complement pathway often result in complement-mediated damage to the microvascular endothelium and can be associated with both glomerulonephritis and atypical haemolytic uraemic syndrome. Inherited defects in complement regulatory genes or autoantibodies against complement regulatory proteins are predictive of the severity of the disease and the risk of recurrence post kidney transplantation. Heterozygous mutations in CD46, which codes for a transmembrane cofactor glycoprotein membrane cofactor protein, usually have a lower incidence of end-stage kidney disease and decreased risk of recurrent disease post transplant, as wild-type membrane cofactor protein is present in the transplanted kidney...
February 2017: Nephrology
https://www.readbyqxmd.com/read/28107310/the-renin-inhibitor-aliskiren-protects-rat-lungs-from-the-histopathologic-effects-of-fat-embolism
#6
Amanda N Fletcher, Agostino Molteni, Rakesh Ponnapureddy, Chirag Patel, Mark Pluym, Alan M Poisner
BACKGROUND: Fat embolism (FE) and the consequent FE syndrome occurring after trauma or surgery can lead to serious pulmonary injury, including ARDS and death. Current treatment of FE syndrome is limited to supportive therapy. We have shown in a rat model that the renin angiotensin system plays a significant role in the pathophysiology of FE because drugs interfering with the renin angiotensin system, captopril and losartan reduce the histopathologic pulmonary damage. The purpose of the current study was to determine if inhibition of renin by aliskiren, an FDA-approved drug for treating hypertension, would produce effective protection in the same model...
February 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28090416/post-traumatic-arthritis-of-the-tarsometatarsal-joint-complex-a-case-report
#7
Chirag Kapoor, Amit Patel, Maulik Jhaveri, Paresh Golwala
Tarsometatarsal (TMT) arthritis is characterized by instability and pain in the foot. The commonest cause is post-traumatic arthritis. A Lisfranc injury involves the articulation between the medial cuneiform and the base of the second metatarsal, which is considered a keystone to midfoot integrity. Neglected or undertreated injury to the Lisfranc joint complex leads to secondary arthritis and significant disability. We present a case of a young male patient with a two-year-old neglected Lisfranc joint injury and secondary osteoarthritis of the first, second, and fourth TMT joints, which we treated surgically with arthrodesis using screws, with a good functional outcome on final follow-up...
December 9, 2016: Curēus
https://www.readbyqxmd.com/read/28073808/fifteen-minute-consultation-assessment-of-a-child-with-suspected-shunt-problems
#8
Harpreet Singh Mangat, Chirag Patel, Desiderio Rodrigues
Cerebrospinal fluid diversion procedures have saved more lives than any other neurosurgical procedure. However, they do have a unique set of complications which a paediatrician in a district general hospital may encounter. Timely recognition and appropriate referral to the neurosurgeon is vital in order to avoid serious consequences and to have a favourable outcome.
January 10, 2017: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/28068484/informatics-and-data-analytics-to-support-exposome-based-discovery-for-public-health
#9
Arjun K Manrai, Yuxia Cui, Pierre R Bushel, Molly Hall, Spyros Karakitsios, Carolyn J Mattingly, Marylyn Ritchie, Charles Schmitt, Denis A Sarigiannis, Duncan C Thomas, David Wishart, David M Balshaw, Chirag J Patel
The complexity of the human exposome-the totality of environmental exposures encountered from birth to death-motivates systematic, high-throughput approaches to discover new environmental determinants of disease. In this review, we describe the state of science in analyzing the human exposome and provide recommendations for the public health community to consider in dealing with analytic challenges of exposome-based biomedical research. We describe extant and novel analytic methods needed to associate the exposome with critical health outcomes and contextualize the data-centered challenges by drawing parallels to other research endeavors such as human genomics research...
March 20, 2017: Annual Review of Public Health
https://www.readbyqxmd.com/read/28053388/prevalence-of-deep-vein-thrombosis-in-patients-with-lower-limb-trauma
#10
Chirag S Kapoor, Ashit K Mehta, Krunal Patel, Paresh P Golwala
INTRODUCTION: Venous thrombo-embolism (VTE), which consists of deep vein thrombosis (DVT) and pulmonary embolism, is a potentially fatal condition. According to Western literature, DVT of lower limb veins is one of the most common complications following surgeries for lower limb. Few studies have been published from India on the subject and little is known about the true prevalence of the DVT and hence there are no clear guidelines regarding the prophylaxis for DVT for Indian patients...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28052169/updated-estimates-of-ectopic-pregnancy-among-commercially-and-medicaid-insured-women-in-the-united-states-2002-2013
#11
Guoyu Tao, Chirag Patel, Karen W Hoover
OBJECTIVES: To update trends in the rates of ectopic pregnancy, to compare rates of ectopic pregnancy between commercially insured and Medicaid-insured women, and to assess the differences in rates of ectopic pregnancy by different measures of ectopic pregnancy. METHODS: We analyzed data from 2002 to 2013 using the Truven Health MarketScan Commercial and Medicaid Claims Database. We limited the study population to women aged 15 to 44 years with any pregnancy in each year...
January 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28008773/radiotherapy-response-evaluation-using-fdg-pet-ct-established-and-emerging-applications
#12
REVIEW
Helen Cliffe, Chirag Patel, Robin Prestwich, Andrew Scarsbrook
Radiation therapy is a common component of curative cancer treatment. However, there is a significant incidence of treatment failure. In these cases, salvage surgical options are sometimes appropriate. Accurate assessment of response and early recognition of treatment success or failure is therefore critical to guide treatment decisions and impacts on survival and the morbidity of treatment. Traditionally, treatment response has depended upon the anatomical measurement of disease. However, this may not correlate well with the presence of disease, especially after radiotherapy...
March 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28004391/should-race-genotype-interactions-be-considered-in-the-global-development-of-cyp2c19-substrates-a-proposed-framework-using-physiologically-based-pharmacokinetic-modeling
#13
Chirag Patel, Chetan Rathi, Karthik Venkatakrishnan
No abstract text is available yet for this article.
April 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28004011/methods-to-enhance-the-reproducibility-of-precision-medicine
#14
Arjun K Manrai, Chirag J Patel, Nils Gehlenborg, Nicholas P Tatonetti, John P A Ioannidis, Isaac S Kohane
No abstract text is available yet for this article.
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27970169/tct-782-peripheral-arterial-disease-hospitalization-trends-in-usa-2003-2013
#15
Prashant Patel, Shilpkumar Arora, Sopan Lahewala, Byomesh Tripathi, Nilay Patel, Chirag Savani, Kosha Thakore, Aditi Amin, Kriti Narwal, Sidakpal Panaich, Nileshkumar Patel, Apurva Badheka
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970160/tct-773-thrombolysis-catheter-directed-systemic-in-pulmonary-embolism-predictors-and-etiologies-of-readmissions
#16
Prashant Patel, Shilpkumar Arora, Sopan Lahewala, Nilay Patel, Byomesh Tripathi, Purav Shah, Jaimin Trivedi, Harshil Shah, Chirag Bambhroliya, Smit Patel, Sidakpal Panaich, Abhishek Deshmukh, Apurva Badheka
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970082/tct-702-transcatheter-aortic-valve-replacement-predictors-of-30-day-readmission-and-in-hospital-mortality-during-primary-and-readmission
#17
Sidakpal Panaich, Shilpkumar Arora, Nilay Patel, Smit Patel, Harshil Shah, Chirag Savani, Kriti Narwal, Kosha Thakore, Aditi Amin, Sopan Lahewala, Nileshkumar Patel, Ekta Aneja, Abhishek Deshmukh, Apurva Badheka
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970051/tct-673-etiolgies-for-readmission-and-complications-following-transcatheter-aortic%C3%A2-valve-replacement-tavr-a-nationwide-perspective
#18
Ekta Aneja, Nilay Patel, Shilpkumar Arora, Sopan Lahewala, Sidakpal Panaich, Chirag Savani, Kriti Narwal, Smit Patel, Kosha Thakore, Aditi Amin, Nileshkumar Patel, Abhishek Deshmukh, Apurva Badheka
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27903014/effects-of-meteorological-variables-on-the-incidence-of-rupture-of-intracranial-aneurysms-in-central-new-jersey
#19
Marissa Kellogg, Dimitriy Petrov, Nitin Agarwal, Nitesh V Patel, David Richard Hansberry, Prateek Agarwal, Michael Brimacombe, Chirag D Gandhi, Charles Prestigiacomo
Introduction Previous studies have suggested relationships between the rupture of intracranial aneurysms and meteorological variables such as season, barometric pressure, and temperature. Our objective was to examine the relationship between the incidence of hospital admissions secondary to aneurysmal subarachnoid hemorrhage (aSAH) and meteorological variables in central New Jersey. Methods The study population consisted of 312 patients who presented to University Hospital in Newark, New Jersey, between January 1, 2003, and December 31, 2008, with aSAH...
November 30, 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/27900230/giant-cell-tumour-of-proximal-phalanx-of-ring-finger-case-report-and-review-of-literature
#20
Rishit Soni, Chirag Kapoor, Malkesh Shah, Amit Patel, Paresh Golwala
Giant cell tumour (GCT) of bone arising from a phalanx of a finger is extremely rare. Only two percent of all reported GCTs are found in the hand, which show a higher rate of recurrence as compared to those occurring at a more proximal location. Here we report a rare case of giant cell tumour of proximal phalanx of the ring finger in a 20-year-old male, which was treated with extended curettage and bone grafting. After two years of follow-up, the patient was asymptomatic with complete functional recovery and no signs of recurrence...
October 18, 2016: Curēus
keyword
keyword
26214
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"