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Disc replacement

Zhen-Zhen Li, Ya-Liang Huang, Hong-Jun Song, You-Juan Wang, Yan Huang
BACKGROUND: Solitary pulmonary nodules (SPNs) are common imaging findings. Many studies have indicated that F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG-PET/CT) is an accurate test for distinguishing benign and malignant SPNs. The aim of this study was to investigate the value of F-FDG-PET/CT in the diagnosis of malignant SPNs. METHODS: We systematically searched the PubMed and Embase databases up to March 2017, and published data on sensitivity, specificity, and other measures of diagnostic accuracy of F-FDG-PET/CT in the diagnosis of malignant SPNs were meta-analyzed...
March 2018: Medicine (Baltimore)
Che-Wei Hung, Ming-Fang Wu, Gwo-Fane Yu, Chin-Chu Ko, Cheng-Hsing Kao
PURPOSE: To analyze sagittal balance of the cervical spine after three operative methods for three consecutive levels. METHODS: A retrospective case selection and observational study was performed from December 2012 to December 2015: 20 patients underwent anterior cervical discectomy and fusion, 22 patients underwent hybrid surgery (HS), and 20 patients underwent total disc replacement (TDR). Perioperative parameters, clinical outcomes, and preoperative and postoperative sagittal parameters were recorded...
March 9, 2018: Clinical Neurology and Neurosurgery
Jack Zigler, Nicole Ferko, Chris Cameron, Leena Patel
AIM: To compare the efficacy and safety of total disc replacement, lumbar fusion, and conservative care in the treatment of single-level lumbar degenerative disc disease (DDD). MATERIALS & METHODS: A network meta-analysis was conducted to determine the relative impact of lumbar DDD therapies on Oswestry Disability Index (ODI) success, back pain score, patient satisfaction, employment status, and reoperation. Odds ratios or mean differences and 95% credible intervals were reported...
March 2018: Journal of Comparative Effectiveness Research
Behnaz Esmaeili, Solaleh Afkhami, Faezeh Abolghasemzadeh
One common cause for the replacement of a composite restoration is discoloration. This in vitro study evaluated the effect of tea solution on the discoloration of 3 types of composites at different timepoints after curing. For this study, 150 disc-shaped specimens of 3 types of composite resin-a nanohybrid (Filtek Z350), a microhybrid (Filtek Z250), and a microfilled material (Heliomolar)-were prepared. Specimens were randomly divided into 5 subgroups (n = 10) according to the type of composite and the time from curing to immersion in a tea solution (none [immersed immediately], 1 hour, 6 hours, 12 hours, or 24 hours postcuring)...
March 2018: General Dentistry
Selçuk Özdoğan, Cumhur Kaan Yaltırık, Ali Haluk Düzkalır, Nail Demirel, Mustafa Kaya, Başar Atalay
BACKGROUND The aim of this study was to draw attention to rare spinal infections in recurrent failed spinal surgeries. CASE REPORT A 59-year-old female was admitted to the hospital for back pain, which was assessed as a 9 on the visual analogue scale (VAS); the patient reported tiredness and night sweats. She had an operation for L3-4 far lateral disc herniation four years ago. Then another operation for L4-5 disc herniation six months ago and immediately three months later she has an operation with L3-4-5 fixation again...
March 6, 2018: American Journal of Case Reports
Chun-Kun Park, Kyeong-Sik Ryu
Since the launch of cervical total disc replacement (CTDR) in the early 2000s, many clinical studies have reported better outcomes of CTDR compared to those of anterior cervical discectomy and fusion. However, CTDR is still a new and innovative procedure with limited indications for clinical application in spinal surgery, particularly, for young patients presenting with soft disc herniation with radiculopathy and/or myelopathy. In addition, some controversial issues related to the assessment of clinical outcomes of CTDR remain unresolved...
February 2018: Asian Spine Journal
Jigang Lou, Yuanchao Li, Beiyu Wang, Yang Meng, Quan Gong, Hao Liu
BACKGROUND: Most of the current available cervical disc prostheses present a flat surface instead of an arcuate surface which is most similar to the morphology of cervical endplate. Therefore, we designed a novel prosthesis (Pretic-I, Trauson) based on the physiological curvature of the cervical endplate. Biomechanical evaluation of cervical disc replacement (CDR) with this novel prosthesis was performed and compared with the Prestige LP prosthesis. METHODS: Three motion segments of 18 cadaveric cervical specimens (C2-C7) were evaluated with a 75 N follower load...
February 27, 2018: Journal of Orthopaedic Surgery and Research
Wei Yuan, Haiping Zhang, Xiaoshu Zhou, Weidong Wu, Yue Zhu
OBJECTIVE: Artificial cervical disc replacement is expected to maintain normal cervical biomechanics. The effect of Prestige LP prosthesis height on cervical biomechanics has not been thoroughly studied yet. This finite element (FE) study of the cervical biomechanics aims to predict how the parameters like range of motion (ROM), adjacent intradiscal pressure, facet joint force and bone-implant interface stress are affected by different Prestige LP prosthesis heights. METHODS: The FE model of intact cervical spine (C3-C7) was obtained from our previous study, and the model was altered to implant Prestige LP prostheses at the C5-C6 level...
February 17, 2018: World Neurosurgery
Aymeric Faure, Marc Khalifé, Benjamin Thiebaut, François Roubineau, Charles Henri Flouzat Lachaniette, Arnaud Dubory
STUDY DESIGN: Retrospective cohort study OBJECTIVE.: To analyze the clinical and radiographic outcomes of patients undergoing a one-level lumbar total disc replacement (TDR), according to the initial sagittal alignment of the spine. SUMMARY OF BACKGROUND DATA: No authors have highlighted correlation between the initial spino-pelvic parameters and the postoperative outcome after a one-level TDR. METHODS: Seventy-eight patients were included: 14 TDR at L4-L5 and 64 TDR at L5-S1 level...
February 15, 2018: Spine
Anne F Mannion, Franco M Impellizzeri, Michael Leunig, Dezsö Jeszenszy, Hans-Jürgen Becker, Daniel Haschtmann, Stefan Preiss, Tamas F Fekete
PURPOSE: Studies comparing the outcome of spine surgery with that of large-joint replacement report equivocal findings. The patient-reported outcome measures (PROMs) used in such studies are typically generic and may not be sufficiently sensitive to the successes/failures of treatment. This study compared different indices of "success" in patients undergoing surgery for degenerative disorders of the lumbar spine, hip, or knee, using a validated, multidimensional, and joint-specific PROM...
February 19, 2018: European Spine Journal
Steven J McAnany, Robert K Merrill, Samuel C Overley, Jun S Kim, Robert L Brochin, Sheeraz A Qureshi
Study Design: Cost-effectiveness analysis. Objectives: To determine the 7-year cost-effectiveness of cervical disc replacement (CDR) and anterior cervical discectomy and fusion (ACDF). Methods: We analyzed 7-year Short Form-36 Health Survey data collected from the Prestige Cervical Disc investigational device exemption study (IDE). The SF-6D algorithm was used to convert this data into health state utilities. Costs were calculated from the payer perspective, and quality adjusted life years (QALYs) were used to represent effectiveness...
February 2018: Global Spine Journal
Steven J McAnany, Robert K Merrill, Robert L Brochin, Samuel C Overley, Jun S Kim, Sheeraz A Qureshi
Study Design: Health utility analysis. Objectives: To determine the health state utility (HSU) of 1- and 2-level anterior cervical discectomy and fusion (ACDF) and cervical disc replacement (CDR). Methods: Data from the Medtronic Prestige Cervical Disc investigational device exemption studies was used. Four groups were defined: 1-level ACDF, 1-level CDR, 2-level ACDF, and 2-level CDR. The 36-item Short Form Health Survey (SF-36) was collected at baseline, 12 months, 24 months, 36 months, and 60 months postoperatively and converted into utility scores for each time point...
February 2018: Global Spine Journal
Da Bao, Dawei Li
Artificial disc replacement alone is unable to completely cure cervical degenerative diseases; thus, a stabilization device markedly improves patient recovery. In order to meet this requirement, an anterior spinal instrumentation combining a prosthetic disc nucleus with a flexible stabilization device (ASI combining PDN/FD) was developed. An artificial disc was designed and manufactured using polyvinyl alcohol hydrogel (PVA-H) with a repeated freeze-melting technique, and subsequently the dehydration and swelling properties of the PVA-H were investigated...
March 2018: Experimental and Therapeutic Medicine
Vittoria Bucknall, Jn Alastair Gibson
Cervical endoscopic spinal surgery (CESS) is now regularly performed in some centres in the Far East, yet rarely in Europe and the United States. This review describes the application of CESS through anterior and posterior approaches with analysis of the available evidence supporting current techniques. An electronic literature search identified 52 papers and proceedings' abstracts of which 25 (16 anterior approach and 9 posterior approach) provided comparable clinical outcomes. The results revealed a good or excellent outcome from CESS in 91% (range 74-100%) with a complication rate of 5%...
January 2018: Journal of Orthopaedic Surgery
Ebenezer Daniel, Wei Pan, Gui-Shuang Ying, Benjamin J Kim, Juan E Grunwald, Frederick L Ferris, Glenn J Jaffe, Cynthia A Toth, Daniel F Martin, Stuart L Fine, Maureen G Maguire
PURPOSE: To describe risk factors for scar formation and changes to fibrotic scar through 5 years in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). DESIGN: Multicenter, prospective cohort study. PARTICIPANTS: A total of 1061 subjects in CATT. METHODS: Color photographic and fluorescein angiographic images from baseline and 1, 2, and 5 years were evaluated. Incidence of scar formation was estimated with Kaplan-Meier curves...
February 14, 2018: Ophthalmology
Sarah E Gullbrand, Dong Hwa Kim, Edward Bonnevie, Beth G Ashinsky, Lachlan J Smith, Dawn M Elliott, Robert L Mauck, Harvey E Smith
Replacement of the intervertebral disc with a viable, tissue-engineered construct that mimics native tissue structure and function is an attractive alternative to fusion or mechanical arthroplasty for the treatment of disc pathology. While a number of engineered discs have been developed, the average size of these constructs remains a fraction of the size of human intervertebral discs. In this study, we fabricated medium (3 mm height x 10 mm diameter) and large (6 mm height x 20 mm diameter) sized disc-like angle ply structures (DAPS), encompassing size scales from the rabbit lumbar spine to the human cervical spine...
February 7, 2018: Acta Biomaterialia
Kristine M Fischenich, Jackson T Lewis, Travis S Bailey, Tammy L Haut Donahue
Hydrogels are a class of synthetic biomaterials composed of a polymer network that swells with water and as such they have both an elastic and viscous component making them ideal for soft tissue applications. This study characterizes the compressive, tensile, and shear properties of a thermoplastic elastomer (TPE) hydrogel and compares the results to published literature values for soft tissues such as articular cartilage, the knee meniscus, and intervertebral disc components. The results show the TPE hydrogel material is viscoelastic, strain rate dependent, has similar surface and bulk properties, displays minimal damping under dynamic load, and has tension-compression asymmetry...
March 2018: Journal of the Mechanical Behavior of Biomedical Materials
Kai-Feng Wang, Shuo Duan, Zhen-Qi Zhu, Hai-Ying Liu, Chen-Jun Liu, Shuai Xu
OBJECTIVE: To assess the mid-long-term follow-up of the safety and efficacy of anterior cervical discectomy and fusion (ACDF), cervical artificial disc replacement (CADR) and hybrid surgery (HS) for bi-level cervical degenerative disc disease (cDDD). METHODS: 77 patients who underwent ACDF, HS and CADR were retrospectively reviewed. Clinical effects were evaluated based on NDI, VAS and JOA scores, and the Odom criteria. Radiographic outcomes were evaluated, including cervical range of motion(ROM), operative and adjacent segments ROM, incidence of adjacent segments degeneration(ASD) and heterotopic ossification(HO)...
January 30, 2018: World Neurosurgery
Espen Helgeland, Siddharth Shanbhag, Torbjorn O Pedersen, Kamal Mustafa, Annika Rosén
Reconstruction of degenerated temporomandibular joint (TMJ) structures remains a clinical challenge. Tissue engineering (TE) is a promising alternative to current treatment options where the TMJ is either left without functional components, or replaced with autogenous, allogenic, or synthetic grafts. The objective of this systematic review was to answer the focused question: in experimental animal models, does the implantation of biomaterial scaffolds loaded with cells and/or growth factors (GFs) enhance regeneration of the discal or osteochondral TMJ tissues, compared to scaffolds alone, without cells or GFs? Following PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analysis) guidelines, electronic databases were searched for relevant controlled preclinical in vivo studies...
February 5, 2018: Tissue Engineering. Part B, Reviews
S D Heintze, D Monreal, M Reinhardt, A Eser, A Peschke, J Reinshagen, V Rousson
OBJECTIVE: To estimate the fatigue resistance of a new translucent zirconia material in comparison to lithium disilicate for 3-unit fixed partial dentures (FPDs). METHODS: Eighteen 3-unit FPDs (replacement of first upper molar) with a connector size of 4mm×4mm were dry milled with a five-axis milling machine (Zenotec Select, Wieland, Germany) using discs made of a new translucent zirconia material (IPS e.max ZirCAD MT, Ivoclar Vivadent). Another 9 FPDs with a reduced connector size (3mm×4mm) were milled...
January 27, 2018: Dental Materials: Official Publication of the Academy of Dental Materials
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