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https://www.readbyqxmd.com/read/29764039/-long-term-efficacy-of-cervical-artificial-disc-replacement-for-cervical-degenerative-diseases
#1
Q P Song, W Tian, D He, X Han, N Zhang, J C Wang, Z C Li
Objective: To evaluate the long-term efficacy of cervical artificial disc replacement for patients with cervical disc herniation and degenerative cervical canal stenosis. Methods: Total of sixty-eight patients underwent single-level Bryan artificial disc replacement in Beijing Jishuitan Hospital from December 2003 to December 2007 with a minimum 10-year follow-up were retrospectively analyzed. There were 43 males and 25 females with a mean age of (46±8) years. According to preoperative CT and MRI, the patients were divided into two groups: 27 patients in cervical disc herniation group and 41 patients in degenerative cervical canal stenosis group...
May 8, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29753897/comparison-of-multilevel-cervical-disc-replacement-and-multilevel-anterior-discectomy-and-fusion-a-systematic-review-of-biomechanical-and-clinical-evidence
#2
REVIEW
Yang Li, Hangkai Shen, Kamran Z Khan, Shushu Fang, Zhenhua Liao, Weiqiang Liu
The present study aimed to comprehensively compare the clinical and biomechanical efficiency of combined anterior cervical discectomy and fusion (ACDF) with the anterior cervical disc replacement (ACDR) for treatment of multilevel cervical disc diease (CDD) using a meta-analysis and systematical review. A literature search was performed using Pubmed, MEDLINE, EMBASE and the Cochrane Library for papers published between January 1960 and December 2017. Both clinical and biomechanical parameters were analyzed...
May 10, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29753275/cervical-spine-fracture-through-a-cervical-disc-replacement
#3
M Flanagan, D T Cawley, N Cassidy
INTRODUCTION: We report a rare case of cervical spine trauma through a cervical disc replacement and adjacent multilevel disc fusions. Cervical disc replacement (CDR) is a viable option for the surgical treatment of degenerative disc disease however long term follow up data regarding this operative technique is poor specifically relating to traumatic complications. We know of no previous reports of bilateral cervical pedicle fractures occurring adjacent to CDR and anterior cervical spine instrumentation...
March 29, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29750169/drosophila-as-a-model-system-to-study-cell-signaling-in-organ-regeneration
#4
REVIEW
Sara Ahmed-de-Prado, Antonio Baonza
Regeneration is a fascinating phenomenon that allows organisms to replace or repair damaged organs or tissues. This ability occurs to varying extents among metazoans. The rebuilding of the damaged structure depends on regenerative proliferation that must be accompanied by proper cell fate respecification and patterning. These cellular processes are regulated by the action of different signaling pathways that are activated in response to the damage. The imaginal discs of Drosophila melanogaster have the ability to regenerate and have been extensively used as a model system to study regeneration...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29748491/the-effect-of-kinematic-conditions-and-synovial-fluid-composition-on-the-frictional-behaviour-of-materials-for-artificial-joints
#5
David Nečas, Martin Vrbka, Ivan Křupka, Martin Hartl
The paper introduces an experimental investigation of frictional behaviour of materials used for joint replacements. The measurements were performed using a ball-on-disc tribometer, while four material combinations were tested; metal-on-metal, ceramic-on-ceramic, metal-on-polyethylene, and ceramic-on-polyethylene, respectively. The contact was lubricated by pure saline and various protein solutions. The experiments were realized at two mean speeds equal to 5.7 mm/s and 22 mm/s and two slide-to-roll ratios, −150% and 150%...
May 10, 2018: Materials
https://www.readbyqxmd.com/read/29734212/time-course-of-radiologic-changes-after-lumbar-total-disc-replacement-experience-of-single-institute-with-minimum-5-year-follow-up
#6
Jung-Woo Hur, Jin-Sung Kim, Kyeong-Sik Ryu, Myeong-Hoon Shin, Chun-Kun Park
STUDY DESIGN: This was a retrospective observatory analysis study. OBJECTIVE: The purpose of this study was to evaluate long-term safety and therapeutic effectiveness of the lumbar total disc replacement (TDR) using ProDisc-L by analyzing the radiologic changes at the index and adjacent levels in minimum 5-year follow-up. SUMMARY OF BACKGROUND DATA: Early successful clinical results of lumbar TDR have been reported. However, few reports have published its therapeutic effectiveness and radiologic degenerative changes at the index and adjacent segments in the long term...
May 4, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29709550/is-the-behavior-of-disc-replacement-adjacent-to-fusion-affected-by-the-location-of-the-fused-level-in-hybrid-surgery
#7
Ting-Kui Wu, Yang Meng, Bei-Yu Wang, Ying Hong, Xin Rong, Chen Ding, Hua Chen, Hao Liu
BACKGROUND: Context: Hybrid surgery (HS), consisting of cervical disc arthroplasty (CDA) at the mobile level, along with anterior cervical discectomy and fusion (ACDF) at the spondylotic level, could be a promising treatment for patients with multilevel cervical degenerative disc disease (DDD). An advantage of this technique is that it utilizes an optimal procedure according to the status of each level. However, information is lacking regarding the influence of the relative location of the replacement and the fusion segment in vivo...
April 27, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29679738/the-auricular-cartilage-graft-used-as-interpositional-material-for-disc-replacement-after-failed-tmj-operative-arthroscopy
#8
Mario Fernando Muñoz-Guerra, Francisco José Rodríguez-Campo, Manuel Fernández-Domínguez
OBJECTIVES: The aim of this study was to evaluate the preoperative and 2-years postoperative clinical and radiological findings in a group of patients after temporomandibular joint discectomy and interpositional autogenous auricular cartilage graft. MATERIALS AND METHODS: The technique involved a disc removal, condylar remodeling and fixation of the graft to the fossa-eminence region. Preoperative and 2-years postoperative clinical findings and magnetic resonance features were evaluated in a group of 13 patients (fourteen joints)...
April 18, 2018: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29673061/decellularization-and-characterization-of-a-whole-intervertebral-disc-xenograft-scaffold
#9
Austin Hensley, Jess Rames, Victor Casler, Christopher Rood, Joshua Walters, Christopher Fernandez, Sanjitpal Gill, Jeremy Mercuri
Intervertebral disc (IVD) degeneration is a multi-factor process that results in the physical destruction of the nucleus pulposus (NP) and annulus fibrosus (AF). This compromises IVD function and causes significant disability and economic burden. Strategies to replace the entire composite structure of the IVD are limited and most approaches do not recapitulate the heterogenous biochemical composition, micro-architecture or mechanical properties of the native tissue. Our central hypothesis was that donor IVDs which resemble the size and biochemistry of human lumbar IVDs could be successfully decellularized while retaining the tissue's structure and function with the long-term goal of creating a composite scaffold for tissue engineering the human IVD...
April 19, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29671017/-degenerative-cervical-spine-diseases-fusion-vs-total-disc-replacement-what-can-be-done-when
#10
REVIEW
T Pitzen, J Drumm, C Berthold, G Ostrowski, U Heiler, M Ruf
Motion preserving surgery within the cervical spine may be performed by special implants, for example, c spine disc prosthesis or total disc replacement (cTDR), or by simple decompression of the cervical nerve roots. However, also fusion surgery may be performed with good results. Here, we summarize indications as well as contraindications for motion preserving techniques and indications for fusion surgery. cTDR is indicated in special cases of soft disc herniation, especially in younger individuals without signs of myelopathy...
April 18, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29668575/comparison-of-the-adverse-events-of-anterior-cervical-disc-replacement-versus-anterior-cervical-discectomy-and-fusion-a-protocol-for-a-systematic-review-and-meta-analysis-of-prospective-randomized-controlled-trials
#11
He Zhao, Li-Jun Duan, Yu-Shan Gao, Yong-Dong Yang, Xiang-Sheng Tang, Ding-Yan Zhao, Yang Xiong, Zhen-Guo Hu, Chuan-Hong Li, Si-Xue Chen, Tao Liu, Xing Yu
BACKGROUND: In the current surgical therapeutic regimen for symptomatic cervical degenerative disc disease, both anterior cervical discectomy and fusion (ACDF) and anterior cervical disc replacement (ACDR) are still widely accepted. However, many complications exist in both surgeries. Therefore, this study aims to compare the adverse events between ACDR and ACDF, and provide vital evidence-based guidance for spine surgeons and designers to evaluation of prognosis and improvement of dynamic devices...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29662742/total-disc-replacement-versus-anterior-posterior-interbody-fusion-in-the-lumbar-spine-and-lumbosacral-junction-a-cost-analysis
#12
Timo Stubig, Malik Ahmed, Amir Ghasemi, Luigi Aurelio Nasto, Michael Grevitt
Study Design: Prospective observational cohort study. Objectives: To analyze clinical and economic results in patients with degenerative disc disease in the lumbar area for patients who received combined anterior and posterior fusion or total disc replacement (TDR). Methods: The study included 75 patients, 38 in the fusion group and 37 in the TDR group, who received either anterior/posterior fusion or TDR for lumbar disc disease from January 2005 to December 2008 with a minimum follow-up of 24 months...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29660649/tribological-evaluation-of-biomedical-polycarbonate-urethanes-against-articular-cartilage
#13
Yusuf Kanca, Piers Milner, Daniele Dini, Andrew A Amis
This research investigated the in-vitro wear and friction performance of polycarbonate urethane (PCU) 80A as they interact with articular cartilage, using a customised multidirectional pin-on-plate tester. Condyles were articulated against PCU 80A discs (Bionate® I and Bionate® II) (configuration 1) and the results arising from these tests were compared to those recorded during the sliding of PCU pins against cartilage plates (configuration 2). Configuration 1 produced steadily increasing coefficient of friction (COF) (up to 0...
April 3, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29658148/biochemical-and-biomechanical-characterization-of-equine-cervical-facet-joint-cartilage
#14
S A O'Leary, J L White, J C Hu, K A Athanasiou
BACKGROUND: The equine cervical facet joint is a site of significant pathology. Located bilaterally on the dorsal spine, these diarthrodial joints work in conjunction with the intervertebral disc to facilitate appropriate spinal motion. Despite the high prevalence of pathology in this joint, the facet joint is understudied and thus lacking in viable treatment options. OBJECTIVE: The goal of this study was to characterise equine facet joint cartilage and provide a comprehensive database describing the morphological, histological, biochemical, and biomechanical properties of this tissue...
April 15, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29627629/hybrid-constructs-for-performing-three-level-hybrid-surgery-a-finite-element-study
#15
Yang Li, Jia Zhu, Zhenhua Liao, Zhenjun Zhang, Weiqiang Liu
This study aimed to systematically investigate the effect of three-level hybrid constructs on the cervical spine biomechanics based on a validated model of the C3-C7 segments. Three hybrid constructs with two U-shaped dynamic cervical implants (DCIs) and one cage were simulated. The three constructs were (1) Cage-U-U (cage implanted at the C3-C4 level and U-shaped DCIs implanted at the C4-C5 and C5-C6 levels), (2) U-Cage-U, and (3) U-U-Cage. Biomechanical parameters including moments, cervical motions, and stresses in the facet and implants were analyzed in flexion and extension...
April 5, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29621263/wide-scan-imaging-with-swept-source-optical-coherent-tomography-for-glaucoma-diagnosis
#16
Eun Hee Hong, Yong Un Shin, Min Ho Kang, Heeyoon Cho, Mincheol Seong
PURPOSE: To determine glaucoma-discriminating abilities of macular and circumpapillary retinal nerve fiber layer (cpRNFL) thickness measurements of wide scan (12X9mm) using swept-source optical coherence tomography (SS-OCT) compared to measurements of standard macula and disc scans (6 X 6 mm). METHODS: This retrospective chart review study included 60 glaucomatous and 62 healthy eyes of total 122 subjects who visited a glaucoma clinic and were examined with wide, standard macula, and standard disc scans of SS-OCT (DRI-OCT-1 Atlantis; Topcon Inc...
2018: PloS One
https://www.readbyqxmd.com/read/29615017/clinical-and-radiographic-outcome-of-dynamic-cervical-implant-dci-arthroplasty-for-degenerative-cervical-disc-disease-a-minimal-five-year-follow-up
#17
Lin-Nan Wang, Bo-Wen Hu, Lei Wang, Yue-Ming Song, Xi Yang, Li-Min Liu, Hao Liu
BACKGROUND: To evaluate the mid- to long-term clinical and radiographic outcomes of anterior cervical discectomy and dynamic cervical implant (DCI) arthroplasty for degenerative cervical disc disease. METHODS: From April 2010 to October 2010, 38 patients with single- or double-level cervical disc herniation underwent anterior cervical discectomy and DCI arthroplasty. The clinical results and radiographic outcomes of these 38 patients (42 levels) were retrospectively evaluated...
April 4, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29605718/a-novel-mouse-model-of-intervertebral-disc-degeneration-shows-altered-cell-fate-and-matrix-homeostasis
#18
Hyowon Choi, Steven Tessier, Elizabeth S Silagi, Rutvin Kyada, Farzad Yousefi, Nancy Pleshko, Irving M Shapiro, Makarand V Risbud
Intervertebral disc degeneration and associated low back and neck pain is a ubiquitous health condition that affects millions of people world-wide, and causes high incidence of disability and enormous medical/societal costs. However, lack of appropriate small animal models with spontaneous disease onset has impeded our ability to understand the pathogenetic mechanisms that characterize and drive the degenerative process. We report, for the first time, early onset spontaneous disc degeneration in SM/J mice known for their poor regenerative capacities compared to "super-healer" LG/J mice...
March 29, 2018: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/29595628/what-is-the-superior-surgical-strategy-for-bi-level-cervical-spondylosis-anterior-cervical-disc-replacement-or-anterior-cervical-decompression-and-fusion-a-meta-analysis-from-11-studies
#19
REVIEW
He Zhao, Li-Jun Duan, Yu-Shan Gao, Yong-Dong Yang, Xiang-Sheng Tang, Ding-Yan Zhao, Yang Xiong, Zhen-Guo Hu, Chuan-Hong Li, Xing Yu
BACKGROUND: Nowadays, anterior cervical artificial disc replacement (ACDR) has achieved favorable outcomes in treatment for patients with single-level cervical spondylosis. However, It is still controversial that whether or not it will become a potent therapeutic alternation in treating 2 contiguous levels cervical spondylosis compared with anterior cervical decompression and fusion (ACDF). Therefore, we conducted a systematic review and meta-analysis to compare the efficacy and safety of ACDR and ACDF in patients with 2 contiguous levels cervical spondylosis...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29581890/recurrent-discitis-in-the-acute-rehab-setting-a-case-report
#20
Kunj Patel, Lauren Hutts, Stephen Porter, Zachary Fausel, Dale Strasser
Introduction: Discitis is an infection of the intervertebral disc space that can lead to paralysis, sepsis, epidural abscess, or other life-threatening complications if left untreated and may sometimes present with limited laboratory abnormalities to clue a diagnosis. Case presentation: We present a case of a 67-year-old female in an acute rehabilitation setting who had presenting symptoms of sudden unexplained back pain refractory to pain control. She had a previous history of discitis and multiple failed knee replacement surgeries secondary to MSSA infections...
2018: Spinal Cord Series and Cases
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