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https://www.readbyqxmd.com/read/29245175/development-and-testing-of-a-hybrid-measure-of-muscle-strength-in-juvenile-dermatomyositis-for-use-in-routine-care
#1
Giulia Camilla Varnier, Silvia Rosina, Cristina Ferrari, Angela Pistorio, Alessandro Consolaro, Francesca Bovis, Sara Dalprà, Clarissa Pilkington, Susan Maillard, Adele Civino, Elena Tsitsami, Jaime de Inocencio, Marija Jelusic, Jelena Vojinovic, Graciela Espada, Balahan Makay, Maria Martha Katsicas, Polixeni Pratsidou-Gertsi, Dragana Lazarevic, Anand Prahalad Rao, Denise Pires Marafon, Nicolino Ruperto, Alberto Martini, Angelo Ravelli
OBJECTIVE: To develop and test a hybrid measure of muscle strength for juvenile dermatomyositis (JDM), which is based on the combination of the Manual Muscle Testing 8 (MMT8) and the Childhood Myositis Assessment Scale (CMAS), but is more comprehensive than the former and more feasible than the latter. METHODS: The hybrid MMT/CMAS (hMC) is composed of all 8 items of the MMT8 and 3 items of the CMAS: 1) time of head lift; 2) assessment of abdominal muscles; 3) floor rise...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245154/acute-procedural-outcomes-of-orbital-atherectomy-for-the-treatment-of-profunda-femoris-artery-disease-subanalysis-of-the-confirm-registries
#2
Michael S Lee, Pratyaksh K Srivastava, Saif Al Yaseen, Daniel Heikali, John Hollowed, Ehtisham Mahmud
OBJECTIVES: We compared the angiographic outcomes of patients treated with orbital atherectomy for profunda femoris artery (PFA) and superficial femoral artery (SFA) disease from the CONFIRM I-III registries. BACKGROUND: Endovascular revascularization of the PFA is considered a high-risk procedure given that it is an important collateral vessel when the SFA becomes occluded. Data on outcomes of endovascular revascularization of calcified PFA disease are limited...
December 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29245153/catheter-ablation-of-focal-atrial-tachycardia-using-remote-magnetic-navigation
#3
Xiao-Yu Liu, Peter Karl Jacobsen, Steen Pehrson, Xu Chen
OBJECTIVES: The outcomes of catheter ablation in focal atrial tachycardia (AT) using remote magnetic navigation (RMN) are still controversial. The objectives of this study were to assess the acute and long-term outcomes of catheter ablation in focal AT using RMN. BACKGROUND: A total of 53 patients with focal AT who underwent catheter ablation using RMN were included. Thirty-six patients had structural heart disease, including previous atrial fibrillation ablation and heart surgery (abnormal group), and the remaining 17 patients had no structural heart disease (normal group)...
December 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29245152/operator-pelvic-radiation-exposure-during-percutaneous-coronary-procedures
#4
Alessandro Sciahbasi, Emanuela Piccaluga, Alessandro Sarandrea, Giacomo Nucci, Nicola Caretto, Stefano Rigattieri, Silvio Fedele, Silvio Romano, Maria Penco
OBJECTIVES: To evaluate operator pelvic radiation exposure during percutaneous coronary procedures. BACKGROUND: During percutaneous coronary procedures, the operator's pelvic region is close to the x-ray source and is probably exposed to more radiation than the operator's thorax. However, no data are available on the pelvic radiation exposure of interventional cardiologists. METHODS: The RADIANT study (NCT01974453) is a prospective, single-center, observational study evaluating operator radiation exposure during percutaneous coronary procedures using electronic dosimeters placed at thorax level...
December 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29245099/total-bilateral-tmj-reconstruction-for-pain-and-dysfunction-case-report
#5
Carlos Vinícius Ayres Moreira, André Victor Pinto Serra, Larissa Oliveira Ramos Silva, Ana Carolina Fraga Fernandes, Roberto Almeida de Azevedo
INTRODUCTION: Temporomandibular disorders encompass a set of clinical conditions that affect the temporomandibular joint, the masticatory muscles and the associated tissues. Many therapeutic alternatives can be considered, being divided into non-invasive, minimally invasive and invasive interventions. This work aims to report a case of inflammatory joint pain and dysfunction treated with bilateral TMJ full reconstruction with alloplastic prosthesis stock. CASE REPORT: Patient D...
December 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29245084/application-of-analytical-quality-by-design-principles-for-the-determination-of-alkyl-p-toluenesulfonates-impurities-in-aprepitant-by-hplc-validation-using-total-error-concept
#6
Constantinos K Zacharis, Elli Vastardi
In the research presented we report the development of a simple and robust liquid chromatographic method for the quantification of two genotoxic alkyl sulphonate impurities (namely methyl p-toluenesulfonate and isopropyl p-toluenesulfonate) in Aprepitant API substances using the Analytical Quality by Design (AQbD) approach. Following the steps of AQbD protocol, the selected critical method attributes (CMAs) were the separation criterions between the critical peak pairs, the analysis time and the peak efficiencies of the analytes...
December 7, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29245083/concordance-between-the-wada-test-and-neuroimaging-lateralization-influence-of-imaging-modality-fmri-and-meg-and-patient-experience
#7
Steven Kemp, Garreth Prendergast, Theodoros Karapanagiotidis, Gus Baker, Thomas P Kelly, Tufail Patankar, Simon S Keller
The Wada test remains the traditional test for lateralizing language and memory function prior to epilepsy surgery. Functional imaging, particularly functional MRI (fMRI), has made progress in the language domain, but less so in the memory domain. Magnetoencephalography (MEG) has received less research attention, but shows promise, particularly for language lateralization. We recruited a consecutive sample of 19 patients with epilepsy who had completed presurgical work-up, including the Wada test, and compared fMRI (memory) and MEG (language and memory) with Wada test results...
December 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29245004/a-standardized-preoperative-group-intervention-is-feasible-and-acceptable-to-orthognathic-surgery-patients
#8
Xialong Li, Debra L Safer, Imilce Castro Paz, Roseanne Menorca, Sabine Girod
PURPOSE: Nearly 10% of patients remain dissatisfied after orthognathic surgery, largely because of psychoeducational or psychosocial factors. The purpose of this study was to evaluate the feasibility and acceptability of a psychoeducationally based group intervention to improve preoperative preparation of orthognathic surgical patients and their caregivers. MATERIALS AND METHODS: The intervention consisted of 2 group sessions, with each session lasting 2 hours...
November 22, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29245003/a-quantitative-assessment-of-lip-movements-in-different-facial-expressions-through-3-dimensional-on-3-dimensional-superimposition-a-cross-sectional-study
#9
Daniele Gibelli, Marina Codari, Valentina Pucciarelli, Claudia Dolci, Chiarella Sforza
PURPOSE: The quantitative assessment of facial modifications from mimicry is of relevant interest for the rehabilitation of patients who can no longer produce facial expressions. This study investigated a novel application of 3-dimensional on 3-dimensional superimposition for facial mimicry. MATERIALS AND METHODS: This cross-sectional study was based on 10 men 30 to 40 years old who underwent stereophotogrammetry for neutral, happy, sad, and angry expressions. Registration of facial expressions on the neutral expression was performed...
November 23, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29245001/management-of-the-maxillary-diastema-by-various-dental-specialties
#10
Bryan Wheeler, Caroline K Carrico, Bhavna Shroff, Tegman Brickhouse, Daniel M Laskin
PURPOSE: There is considerable controversy in the literature concerning the indications for frenectomy for treating a maxillary diastema and for timing of the procedure. The purpose of this study was to survey pediatric dentists, orthodontists, and oral and maxillofacial surgeons on their opinion of this matter to develop a consensus. MATERIALS AND METHODS: An anonymous 7-item electronic questionnaire was sent to members of the American Academy of Pediatric Dentists, the American Association of Orthodontists, and the American Association of Oral and Maxillofacial Surgeons asking about the etiology of the maxillary diastema, its diagnosis, and treatment...
November 22, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29244970/maggot-debridement-therapy-for-an-electrical-burn-injury-with-instructions-for-the-use-of-lucilia-sericata-larvae
#11
A Nasoori, R Hoomand
OBJECTIVE: Maggot debridement therapy (MDT) has proved an efficient and reliable approach for wound healing. We explain the use of maggots with a stepwise procedure for conducting MDT in a patient with severe and large electrical wounds. METHOD: We captured the flies of Lucilia sericata from the natural environment, Alborz, Iran, and reared them in netted cages. The eggs obtained from the flies were disinfected with chloramine, and then were incubated on culture medium...
December 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29244967/diagnosis-and-treatment-of-chronic-wounds-current-standards-of-germany-s-initiative-for-chronic-wounds-e-v
#12
J Dissemond, A Bültemann, V Gerber, B Jäger, K Kröger, C Münter
The diagnosis and treatment of patients with chronic wounds is an enormous challenge in various disciplines of medicine. These very complex processes usually involve several experts of different medical specialties with varying educational backgrounds. A necessary basis for consistent communication and documentation is the use of unambiguous nomenclature. Therefore, the board of the German wound association, Initiative for Chronic Wounds (ICW) e.V., has started to define various terms and procedures. An easy to remember algorithm, in the form of the ABCDE rule, has been developed for the structured diagnosis of chronic wounds...
December 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29244906/finding-treatment-resistant-depression-in-real-world-data-how-a-data-driven-approach-compares-with-expert-based-heuristics
#13
M Soledad Cepeda, Jenna Reps, Daniel Fife, Clair Blacketer, Paul Stang, Patrick Ryan
BACKGROUND: Depression that does not respond to antidepressants is treatment-resistant depression (TRD). TRD definitions include assessments of treatment response, dose and duration, and implementing these definitions in claims databases can be challenging. We built a data-driven TRD definition and evaluated its performance. METHODS: We included adults with depression, ≥1 antidepressant, and no diagnosis of mania, dementia, or psychosis. Subjects were stratified into those with and without proxy for TRD...
December 15, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/29244887/carbon-fiber-framework-for-full-arch-implant-supported-fixed-dental-prostheses-supporting-resin-based-composite-and-lithium-disilicate-ceramic-crowns-case-report-and-description-of-features
#14
Giuseppe Castorina
This case report presents a new approach for shock-absorbing carbon-fiber composite frameworks for full-arch implant-supported fixed dental prostheses supporting resin-based and lithium disilicate ceramic crowns. It describes the characteristics of the materials used, the procedures for implementing the framework, and the requirements to achieve the best mechanical and clinical properties. The result is a full-arch prosthesis with masticatory load shock-absorption capacities, chemical bonding between materials, good esthetics, and wear similar to natural enamel...
December 15, 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29244886/the-modified-apically-repositioned-flap-technique-a-long-term-4-to-16-years-retrospective-study
#15
João Carnio, Paulo M Camargo, Perry R Klokkevold, Flavia Q Pirih
Attached gingiva is desirable for the maintenance of gingival health. Although many methods are used to increase the zone of attached gingiva, the modified apically repositioned flap (MARF) technique has the advantages of simplicity and predictability. The short-term follow-up of the MARF technique demonstrated an increase in keratinized tissue and attached gingiva. This study evaluated long-term results of the MARF technique as used to increase the apicocoronal dimensions of keratinized tissue and attached gingiva in 28 sites (25 patients; average follow-up of 9 years)...
December 15, 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29244838/muscle-function-in-glenohumeral-joint-stability-during-lifting-task
#16
Yoann Blache, Mickaël Begon, Benjamin Michaud, Landry Desmoulins, Paul Allard, Fabien Dal Maso
Ensuring glenohumeral stability during repetitive lifting tasks is a key factor to reduce the risk of shoulder injuries. Nevertheless, the literature reveals some lack concerning the assessment of the muscles that ensure glenohumeral stability during specific lifting tasks. Therefore, the purpose of this study was to assess the stabilization function of shoulder muscles during a lifting task. Kinematics and muscle electromyograms (n = 9) were recorded from 13 healthy adults during a bi-manual lifting task performed from the hip to the shoulder level...
2017: PloS One
https://www.readbyqxmd.com/read/29244800/hla-dq-genetics-in-children-with-celiac-disease-a-meta-analysis-suggesting-a-two-step-genetic-screening-procedure-starting-with-hla-dq-%C3%AE-chains
#17
Annalisa De Silvestri, Cristina Capittini, Dimitri Poddighe, Chiara Valsecchi, Gianluigi Marseglia, Sara Carlotta Tagliacarne, Valeria Scotti, Chiara Rebuffi, Annamaria Pasi, Miryam Martinetti, Carmine Tinelli
OBJECTIVES: through a meta-analysis, evaluating the distribution of the predisposing HLA genotype to Celiac Disease (CD) in children and providing insights for potential widened screening strategy. STUDY DESIGN: After a systematic search on the association between HLA class II and CD in children, 46 publications were obtained and assessed for eligibility. 13 eligible studies were submitted to data extraction and analysis (10 studies case-control and 3 cohort studies)...
December 15, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29244781/influence-of-sterilization-and-preservation-procedures-on-the-integrity-of-serum-protein-coated-magnetic-nanoparticles
#18
Silvio Dutz, Stephanie Wojahn, Christine Gräfe, Andreas Weidner, Joachim H Clement
Protein-coated magnetic nanoparticles are promising candidates for various medical applications. Prior to their application into a biological system, one has to guarantee that the particle dispersions are free from pathogens or any other microbiologic contamination. Furthermore, to find entrance into clinical routine, the nanoparticle dispersions have to be storable for several months. In this study, we tested several procedures for sterilization and preservation of nanoparticle containing liquids on their influence on the integrity of the protein coating on the surface of these particles...
December 15, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29244762/towards-realistic-urban-traffic-experiments-using-dfrouter-heuristic-validation-and-extensions
#19
Jorge Luis Zambrano-Martinez, Carlos T Calafate, David Soler, Juan-Carlos Cano
Traffic congestion is an important problem faced by Intelligent Transportation Systems (ITS), requiring models that allow predicting the impact of different solutions on urban traffic flow. Such an approach typically requires the use of simulations, which should be as realistic as possible. However, achieving high degrees of realism can be complex when the actual traffic patterns, defined through an Origin/Destination (O-D) matrix for the vehicles in a city, remain unknown. Thus, the main contribution of this paper is a heuristic for improving traffic congestion modeling...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244753/identification-of-a-multicomponent-traditional-herbal-medicine-by-hplc-ms-and-electron-and-light-microscopy
#20
Ju-Han Liu, Yung-Yi Cheng, Chen-Hsi Hsieh, Tung-Hu Tsai
BACKGROUND: Commercial pharmaceutical herbal products have enabled people to take traditional Chinese medicine (TCM) in a convenient and accessible form. However, the quantity and quality should be additionally inspected. To address the issue, a combination of chemical and physical inspection methods were developed to evaluate the amount of an herbal formula, Xiang-Sha-Liu-Jun-Zi-Tang (XSLJZT), in clinical TCM practice. METHODS: A high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS) method with electrospray ionization was developed to measure the herbal biomarkers of guanosine, atractylenolide III, glycyrrhizic acid, dehydrocostus lactone, hesperidin, and oleanolic acid from XSLJZT...
December 15, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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