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Zaiyang Long, Donald J Tradup, Pengfei Song, Scott F Stekel, Shigao Chen, Katrina N Glazebrook, Nicholas J Hangiandreou
Because of the rapidly growing use of ultrasound shear wave elastography (SWE) in clinical practices, there is a significant need for development of clinical physics performance assessment methods for this technology. This study aims to report two clinical medical physicists' tasks: (a) acceptance testing (AT) of SWE function on ten commercial ultrasound systems for clinical liver application and (b) comparison of SWE measurements of targets across vendors for clinical musculoskeletal application. For AT, ten GE LOGIQ E9 XDclear 2...
March 15, 2018: Journal of Applied Clinical Medical Physics
Harshavardhan Nagolu, Sudhakar Kattoju, Chidambaranathan Natesan, Meera Krishnakumar, Sunil Kumar
Objective: The purpose of the study is to investigate the usefulness of acoustic radiation force impulse (ARFI) elastography in the characterization of focal solid liver lesions as benign, malignant, or metastatic using ARFI two-dimensional (2D) imaging and ARFI quantification (shear wave velocities [SWVs]). Materials and Methods: Sixty lesions were included in this study. The lesions were classified into three groups: Group I included benign lesions ( n = 25), Group II included malignant lesions ( n = 27), and Group III included metastatic lesions ( n = 8)...
2018: Journal of Clinical Imaging Science
Sunao Shoji, Akio Hashimoto, Tomoya Nakamura, Shinichiro Hiraiwa, Haruhiro Sato, Yoshinobu Sato, Takuma Tajiri, Akira Miyajima
The present study evaluated three-dimensional shear wave elastography (3D SWE) in the detection of clinically significant prostate cancer. Clinically significant prostate cancer was defined by a minimum of one biopsy core with a Gleason score of 3+4 or 6 with a maximum cancer core length >4 mm. Patients with serum prostate-specific antigen levels of 4.0-20.0 ng/ml who were suspected of having prostate cancer from multi-parametric magnetic resonance imaging (mpMRI) were prospectively recruited. The 3D SWE was performed pre-biopsy, after which patients underwent MRI-transrectal ultrasound image-guided targeted biopsies for cancer-suspicious lesions and 12-core systematic biopsies...
April 2018: Biomedical Reports
Li-Ting Xie, Chun-Hong Yan, Qi-Yu Zhao, Meng-Na He, Tian-An Jiang
Two-dimensional shear wave elastography (2D-SWE) is a rapid, simple and novel noninvasive method that has been proposed for assessing hepatic fibrosis in patients with chronic liver diseases (CLDs) based on measurements of liver stiffness. 2D-SWE can be performed easily at the bedside or in an outpatient clinic and yields immediate results with good reproducibility. Furthermore, 2D-SWE was an efficient method for evaluating liver fibrosis in small to moderately sized clinical trials. However, the quality criteria for the staging of liver fibrosis are not yet well defined...
March 7, 2018: World Journal of Gastroenterology: WJG
Yu-Mee Sohn, Mirinae Seo
PURPOSE: To compare breast stiffness based on shear-wave elastography (SWE) quantitative parameters with histopathologic results diagnosed by ultrasound (US)-guided core needle biopsy (CNB) to determine their association with upgrade rates after surgical excision or follow-up US as well as clinico-radiologic differences between upgrade and non-upgrade groups. MATERIALS AND METHODS: This retrospective study enrolled 225 breast lesions from 225 patients, including 159 benign lesions, 38 high risk lesions and 28 ductal carcinoma in situ (DCIS) diagnosed by US-guided CNB...
March 3, 2018: Clinical Imaging
Ivan Miguel Rosado-Mendez, Lindsey C Carlson, Kaitlin M Woo, Andrew P Santoso, Quinton White Guerrero, Mark L Palmeri, Helen Feltovich, Timothy J Hall
Abnormal parturition, e.g. pre- or post-term birth, is associated with maternal and neonatal morbidity and increased economic burden. This could potentially be prevented by accurate detection of abnormal softening of the uterine cervix. Shear Wave Elasticity Imaging (SWEI) techniques that quantify tissue softness, such as shear wave speed (SWS) measurement, are promising for evaluation of the cervix. Still, interpretation of results can be complicated by biological variability (i.e., spatial variations of cervix stiffness, parity), as well as by experimental factors (i...
March 8, 2018: Physics in Medicine and Biology
Meghan Sahr, Daniel R Sturnick, O Kenechi Nwawka
This Institutional Review Board-approved pilot study attempted to detect the correlation between ultrasound shear wave elastographic measures and tendon loads. Five male fresh-frozen cadaveric Achilles tendons were loaded in 10-N increments from 0 to 60 N. Shear wave velocity measurements within each Achilles tendon were obtained at each load in longitudinal and transverse orientations. Shear wave velocity measurements were correlated with tendon tension on both longitudinal and transverse plane imaging and showed moderate and strong positive correlation coefficients, respectively...
March 8, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Veysel Burulday, Adil Doğan, Mehmet Hamdi Şahan, Şenay Arıkan, Aşkın Güngüneş
OBJECTIVES: The aim of this study was to compare the cross-sectional area and ultrasound elastographic findings of the median nerve of patients with acromegaly and healthy participants. METHODS: The acromegaly group comprised 15 patients with a previous diagnosis of acromegaly, and an age- and sex-matched control group included healthy participants. Strain elastographic and shear wave elastographic findings and the cross-sectional areas of the groups were compared...
March 8, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Cheng Fang, Ounali S Jaffer, Gibran T Yusuf, Eleni Konstantatou, Daniel J Quinlan, Kosh Agarwal, Alberto Quaglia, Paul S Sidhu
Purpose To identify the minimum number of measurements required for the noninvasive assessment of liver fibrosis by using point shear-wave elastography (pSWE) and determine whether the use of a reliability indicator such as interquartile range [IQR]-to-median ratio will affect diagnostic performance. Materials and Methods Ten liver shear-wave velocity (SWV) measurements by pSWE were obtained in 232 participants. Interclass correlation coefficients (ICC) between the median of the first two through the first nine measurements and all 10 measurements were calculated; the minimum number of measurements with ICC greater than 0...
March 6, 2018: Radiology
X-Q Shi, J Li, L Qian, X Xue, J Li, W Wan
AIM: To correlate elastic parameters with collagen fibre shape and arrangement features in breast lesions. MATERIALS AND METHODS: Shear-wave elastography (SWE) was used to measure the stiffness of breast lesions in 54 patients before surgical removal. The value of stiffness was expressed as the mean and maximum elasticity (Emean and Emax). Lesions were sliced and stained with picric acid-sirius red to display the extracellular matrix (ECM) collagen fibre. The categories of the collagen fibres were based on the shape and arrangement features, i...
March 3, 2018: Clinical Radiology
Anand Rattansingh, Hosein Amooshahi, Ravi J Menezes, Florence Wong, Sandra Fischer, Richard Kirsch, Mostafa Atri
OBJECTIVE: To determine the accuracy of shear-wave elastography (SWE) to differentiate low from advanced degrees of liver fibrosis in hepatitis C patients. MATERIAL & METHOD: Consented native/transplant hepatitis C patients underwent SWE using a C1-6 MHz transducer before ultrasound (US)-guided liver biopsy. Five interpretable SWE samples were obtained from the right lobe of the liver immediately before US-guided random biopsy of the right lobe. Average kilopascal (kPa) values were compared to the meta-analysis of histological data in viral hepatitis (METAVIR) fibrosis grading...
March 6, 2018: Journal of Clinical Ultrasound: JCU
Piotr Kijanka, Bo Qiang, Pengfei Song, Carolina Amador Carrascal, Shigao Chen, Matthew W Urban
Ultrasound shear wave elastography (SWE) is emerging as a promising imaging modality for the noninvasive evaluation of tissue mechanical properties. One of the ways to explore the viscoelasticity is through analyzing the shear wave velocity dispersion curves. To explore the dispersion, it is necessary to estimate the shear wave velocity at each frequency. An increase of the available spectrum to be used for phase velocity estimation is significant for a tissue dispersion analysis in vivo. A number of available methods suffer because the available spectrum that one can work with is limited...
March 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Youichi Machida, Akiko Shimauchi, Hidemi Okuma, Mitsuhiro Tozaki, Sachiko Isobe, Eisuke Fukuma
RATIONALE AND OBJECTIVES: We aimed to investigate the relationship between shear wave speed (SWS) of the lesion on preoperative breast ultrasonography (US) and disease-free survival of patients with primary operable invasive breast cancer. MATERIALS AND METHODS: This retrospective study was approved by our Institutional Review Board. The requirement for informed consent was waived. A total of 195 consecutive newly diagnosed invasive breast cancer patients (age 33-83 years; mean 54...
March 1, 2018: Academic Radiology
Yavuz Selim Karatekin, Bedri Karaismailoglu, Gokhan Kaynak, Tahir Ogut, Atilla Suleyman Dikici, Emel Ure Esmerer, Onder Aydingoz, Huseyin Botanlioglu
BACKGROUND: Achilles tendon injuries are one of the most common tendon injuries. Surgical treatment is preferred in young and active patients. Although there are studies which evaluate the repair area with magnetic resonance imaging and ultrasonography after surgical treatment, there are very few studies which analyzes the elasticity of the tendon by quantitative methods. ARFI (acoustic radiation force impulse) elastography is a simple and non-invasive method that can quantitatively measure the elasticity of the soft tissues...
March 2, 2018: Journal of Orthopaedic Surgery and Research
John M Cormack, Mark F Hamilton
Model equations with cubic nonlinearity are developed for a plane shear wave of finite amplitude in a relaxing medium. The evolution equation for progressive waves is solved analytically for a jump in stress that propagates into an undisturbed medium. Weak-shock theory is used to determine the amplitude and location of the shock when the solution predicts a multivalued waveform. The solution is similar to that obtained by Polyakova, Soluyan, and Khokhlov [Sov. Phys. Acoust. 8, 78-82 (1962)] for a compressional wave with quadratic nonlinearity in a relaxing fluid...
February 2018: Journal of the Acoustical Society of America
Sam Eriksson, Hanna Borsiin, Carl-Fredrik Öberg, Hannes Brange, Zoran Mijovic, Christian Sturesson
AIM: To investigate changes in hepatic and splenic stiffness in patients without chronic liver disease during liver resection for hepatic tumors. METHODS: Patients scheduled for liver resection for hepatic tumors were considered for enrollment. Tissue stiffness measurements on liver and spleen were conducted before and two days after liver resection using point shear-wave elastography. Histological analysis of the resected liver specimen was conducted in all patients and patients with marked liver fibrosis were excluded from further study analysis...
February 27, 2018: World Journal of Gastrointestinal Surgery
Panagiotis Kapetas, Paola Clauser, Ramona Woitek, Katja Pinker, Maria Bernathova, Thomas H Helbich, Pascal A Baltzer
Our purpose was to evaluate Virtual Touch IQ (VTIQ) elastography and identify quantitative "rule-in" and "rule-out" thresholds for the probability of malignancy, which can help avoid unnecessary breast biopsies. 189 patients with 196 sonographically evident lesions were included in this retrospective, IRB-approved study. Quantitative VTIQ images of each lesion measuring the respective maximum Shear Wave Velocity (SWV) were obtained. Paired and unpaired, non-parametric statistics were applied for comparisons as appropriate...
February 26, 2018: Scientific Reports
Ahmet Aslan, Ahmet Aktan, Mine Aslan, Yıldız Gülseren, Adnan Kabaalioğlu
OBJECTIVES: To determine the sonoelastographic findings for the normal brachial plexus via shear wave elastography (SWE) and strain elastography (SE) and the reliability of the measurements. METHODS: Thirty-nine healthy adult volunteers were included in the study. The brachial plexus was evaluated with SWE and SE at the interscalene region by 2 observers separately, and the observers were unaware of each other's outcomes. The elastic modulus (kilopascals), shear wave velocity (SWV, meters per second), and strain ratio were obtained...
February 26, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Lei Hu, Nianan He, Lei Ye, Hangcheng Zhou, Wen Zhong, Xinshu Zhang
OBJECTIVES: This study evaluated the stiffness of tissue surrounding thyroid nodules using shear wave elastography (SWE). METHODS: A total of 128 thyroid nodules in 108 patients were examined with conventional ultrasound imaging and SWE. The maximum Young modulus value was measured to evaluate the stiffness of the thyroid nodules (E) and the 2-mm perinodular region (Eshell ). The number of thyroid fibrocytes was evaluated by Masson trichrome staining and image-processing software...
February 26, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Harun Arslan, Harun Egemen Tolunay, Numan Cim, Barış Boza, Alpaslan Yavuz, İbrahim İlik, Hanim Guler Sahin, Recep Yildizhan
OBJECTIVE: In this study, we aimed to evaluate the elasticities of fetal placentas with a single umbilical artery using the Virtual Touch Tissue Quantification (VTTQ) technique. MATERIALS AND METHODS: Pregnant women with fetuses with a single umbilical artery (SUA) and pregnant women with fetuses having three vessel cord (3VC) at 18-22 weeks of gestation were enrolled in the research. The placentas were evaluated and divided into three equal parts as the inner 1/3 of the placenta (fetal edge), the outer 1/3 of the placenta (maternal edge) and the central 1/3 of the placenta (central part)...
February 25, 2018: Journal of Maternal-fetal & Neonatal Medicine
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