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https://www.readbyqxmd.com/read/29694848/customizable-cap-implants-for-neurophysiological-experimentation
#1
Jackson D Blonde, Megan Roussy, Rogelio Luna, Borna Mahmoudian, Roberto A Gulli, Kevin C Barker, Jonathan C Lau, Julio C Martinez-Trujillo
BACKGROUND: Several primate neurophysiology laboratories have adopted acrylic-free, custom-fit cranial implants. These implants are often comprised of titanium or plastic polymers, such as polyether ether ketone (PEEK). Titanium is favored for its mechanical strength and osseointegrative properties whereas PEEK is notable for its lightweight, machinability, and MRI compatibility. Recent titanium/PEEK implants have proven to be effective in minimizing infection and implant failure, thereby prolonging experiments and optimizing the scientific contribution of a single primate...
April 22, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29692668/immune-modulation-of-i-v-immunoglobulin-in-women-with-reproductive-failure
#2
REVIEW
Ae R Han, Sung K Lee
Background: The mechanism of maternal immune tolerance of the semi-allogenic fetus has been explored extensively. The immune reaction to defend from invasion by pathogenic microorganisms should be maintained during pregnancy. An imbalance between the immune tolerance to the fetus and immune activation to the pathogenic organisms is associated with poor pregnancy outcomes. This emphasizes that the immune mechanism of successful reproduction is not just immune suppression, but adequate immune modulation...
April 2018: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/29692221/temporal-trends-in-secondary-prevention-in-myocardial-infarction-patients-discharged-with-left-ventricular-systolic-dysfunction-in-poland
#3
Mariusz Gasior, Marek Gierlotka, Łukasz Pyka, Tomasz Zdrojewski, Bogdan Wojtyniak, Krzysztof Chlebus, Piotr Rozentryt, Jacek Niedziela, Piotr Jankowski, Jadwiga Nessler, Grzegorz Opolski, Piotr Hoffman, Ewa Jankowska, Lech Polonski, Piotr Ponikowski
Background The proportion of patients discharged after myocardial infarction with left ventricular systolic dysfunction remains high and the prognosis is unfavourable. The aim of this study was to analyse the temporal trends in the treatment and outcomes of a nationwide cohort of patients. Methods and results Data from the Polish Registry of Acute Coronary Syndromes and Acute Myocardial Infarction in Poland Registry were combined to achieve complete information on inhospital course, treatment and outcomes. An all-comer population of patients discharged with left ventricular ejection fraction of 40% or less formed the sample population ( n = 28,080)...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29691175/correlation-between-intraoperative-anterior-stability-and-flexion-gap-in-total-knee-arthroplasty
#4
Shinichiro Nakamura, Shinichi Kuriyama, Kohei Nishitani, Hiromu Ito, Koichi Murata, Shuichi Matsuda
BACKGROUND: Instability is a common failure mode after total knee arthroplasty. There have been only a few methods to quantify anterior translation with fixed forces applied during surgery. The purpose of the study was to measure the anterior translation with a new device and to analyze the relationships between the amount of anterior translation and the joint gaps. METHODS: Fifty knees with medial osteoarthritis underwent surgery using a posterior-stabilized implant...
March 21, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29691168/predicting-failure-in-early-acute-prosthetic-joint-infection-treated-with-debridement-antibiotics-and-implant-retention-external-validation-of-the-klic-score
#5
Claudia A M Löwik, Paul C Jutte, Eduard Tornero, Joris J W Ploegmakers, Bas A S Knobben, Astrid J de Vries, Wierd P Zijlstra, Baukje Dijkstra, Alex Soriano, Marjan Wouthuyzen-Bakker
BACKGROUND: Debridement, antibiotics, and implant retention (DAIR) is a widely used treatment modality for early acute prosthetic joint infection (PJI). A preoperative risk score was previously designed for predicting DAIR failure, consisting of chronic renal failure (K), liver cirrhosis (L), index surgery (I), cemented prosthesis (C), and C-reactive protein >115 mg/L (KLIC). The aim of this study was to validate the KLIC score in an external cohort. METHODS: We retrospectively evaluated patients with early acute PJI treated with DAIR between 2006 and 2016 in 3 Dutch hospitals...
March 27, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29691080/implant-failure-after-motec-wrist-joint-prosthesis-due-to-failure-of-ball-and-socket-type-articulation-two-patients-with-adverse-reaction-to-metal-debris-and-polyether-ether-ketone
#6
Teemu Karjalainen, Konsta Pamilo, Aleksi Reito
We describe 2 cases of articulation-related failures resulting in revision surgery after a Motec total wrist arthroplasty: one with an adverse reaction to metal debris and the other with an adverse reaction to polyether ether ketone. In the first patient, blood cobalt and chrome levels were elevated and magnetic resonance imaging showed clear signs of a pseudotumor. The other patient had an extensive release of polyether ether ketone particles into the surrounding synovia due to adverse wear conditions in the cup, leading to the formation of a fluid-filled cyst sac with a black lining and diffuse lymphocyte-dominated inflammation in the synovia...
April 21, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29689393/peak-timing-for-complications-following-adult-spinal-deformity-surgery
#7
Alan H Daniels, Shay Bess, Breton Line, Adam E M Eltorai, Daniel B C Reid, Virginie Lafage, Behrooz A Akbarnia, Christopher P Ames, Oheneba Boachie-Adjei, Douglas C Burton, Vedat Deviren, Han Jo Kim, Robert A Hart, Khaled M Kebaish, Eric O Klineberg, Munish Gupta, Gregory M Mundis, Richard A Hostin, Michael O'Brien, Frank J Schwab, Christopher I Shaffrey, Justin S Smith
BACKGROUND: Overall complication rates for adult spinal deformity (ASD) surgery have been reported, however little data exists on the peak timing associated with specific complications. This study quantifies the peak timing for multiple complication types in an ASD cohort at minimum 2-year follow up. METHODS: Multi-center, prospective analysis of all complications following ASD surgery in a consecutively enrolled cohort was performed. Inclusion criteria were ASD, age ≥ 18 years, spinal fusion ≥ 4 levels, and minimum 2-year follow-up...
April 21, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29688960/design-rationale-for-total-ankle-arthroplasty-systems-an-update
#8
Christopher E Gross, Ariel A Palanca, James K DeOrio
The design of total ankle arthroplasty systems is evolving as a result of findings from longer-term studies. Our understanding of modes of failure has increased, and surgical techniques have become more refined. Currently, five total ankle arthroplasty systems are used in the United States. The landscape has changed considerably in the decade since the latest article reviewing total ankle design was published. Some implants with acceptable intermediate results had much poorer outcomes at 7- to 10-year follow-up...
April 23, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29688304/daily-remote-monitoring-of-implantable-cardioverter-defibrillators-insights-from-the-pooled-patient-level-data-from-three-randomized-controlled-trials-in-time-ecost-trust
#9
Gerhard Hindricks, Niraj Varma, Salem Kacet, Thorsten Lewalter, Peter Søgaard, Laurence Guédon-Moreau, Jochen Proff, Thomas A Gerds, Stefan D Anker, Christian Torp-Pedersen
Aims: Remote monitoring of implantable cardioverter-defibrillators may improve clinical outcome. A recent meta-analysis of three randomized controlled trials (TRUST, ECOST, IN-TIME) using a specific remote monitoring system with daily transmissions [Biotronik Home Monitoring (HM)] demonstrated improved survival. We performed a patient-level analysis to verify this result with appropriate time-to-event statistics and to investigate further clinical endpoints. Methods and results: Individual data of the TRUST, ECOST, and IN-TIME patients were pooled to calculate absolute risks of endpoints at 1-year follow-up for HM vs...
June 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29685709/tritanium-acetabular-cup-in-revision-hip-replacement-a-six-to-ten-years-of-follow-up-study
#10
Hazem A H Hosny, Ahmed El-Bakoury, Sreebala C M Srinivasan, Rathan Yarlagadda, Jonathan Keenan
BACKGROUND: The use of highly porous acetabular components has shown to produce good results in revision acetabular surgery. Their surface characteristics enhance initial fixation and bone ingrowth which are prerequisites for adequate osseointegration. The purpose of this study is to analyze the mid-term to long-term survival, clinical and radiological outcomes using the Tritanium cup (Stryker, Mahwah, NJ) in revision hip surgery. METHODS: This is a retrospective review of all patients who underwent acetabular revision surgery using "Tritanium revision cup" between April 2007 and November 2010 at our institution...
March 27, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29685691/mid-term-clinical-outcomes-after-bailout-drug-eluting-stenting-for-suboptimal-drug-coated-balloon-results-insights-from-a-milan-registry
#11
Satoru Mitomo, Richard J Jabbour, Antonio Mangieri, Marco Ancona, Damiano Regazzoli, Akihito Tanaka, Francesco Giannini, Mauro Carlino, Matteo Montorfano, Alaide Chieffo, Azeem Latib, Antonio Colombo
BACKGROUND: Drug-coated balloon (DCB) is an alternative to drug-eluting stent (DES) for the treatment of small vessel or in-stent restenosis (ISR) lesions, with bailout stenting reserved for poor results after DCB inflation (residual stenosis or dissection). Data regarding bailout stenting with DES are limited. The aim of this study was to evaluate clinical outcomes after bailout stenting with DES for suboptimal DCB results. METHODS: From June 2009 to December 2015, patients who underwent bailout DES implantation for suboptimal results after DCB (residual stenosis > 30% or type C-F dissection) in 2 high-volume centers in Italy were analyzed...
April 13, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29685130/cataract-surgery-in-patients-with-corneal-opacities
#12
Yi-Ju Ho, Chi-Chin Sun, Hung-Chi Chen
BACKGROUND: Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities. METHODS: This retrospective study was conducted in a tertiary medical center. Twenty-three eyes of 19 patients with cataracts and corneal opacities obscuring the pupillary center having received phacoemulsification with IOL insertion without any ancillary techniques were enrolled. The primary study outcome measures were uncorrected and best corrected visual acuity (BCVA), and complications...
April 23, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29684191/importance-of-beta-blocker-dose-in-prevention-of-ventricular-tachyarrhythmias-heart-failure-hospitalizations-and-death-in-primary-prevention-implantable-cardioverter-defibrillator-recipients-a-danish-nationwide-cohort-study
#13
A C Ruwald, G H Gislason, M Vinther, J B Johansen, J C Nielsen, B T Philbert, C Torp-Pedersen, S Riahi, C Jøns
Aims: There is a paucity of studies investigating a dose-dependent association between beta-blocker therapy and risk of outcome. In a nationwide cohort of primary prevention implantable cardioverter-defibrillator (ICD) patients, we aimed to investigate the dose-dependent association between beta-blocker therapy and risk of ventricular tachyarrhythmias (VT/VF), heart failure (HF) hospitalizations, and death. Methods and results: Information on ICD implantation, endpoints, comorbidities, beta-blocker usage, type, and dose were obtained through Danish nationwide registers...
April 19, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29683822/the-brachiocephalic-vein-as-a-safe-and-viable-alternative-to-internal-jugular-vein-for-central-venous-cannulation
#14
Paolo Federico Beccaria, Simona Silvetti, Rosalba Lembo, Giovanni Landoni, Giacomo Monti, Massimo Zambon, Daniela Mamo, Alberto Zangrillo
BACKGROUND: Although many studies have compared success and complication rates for central line insertion sites with and without ultrasound, few have examined the use of the brachiocephalic vein for central venous access. The aim of this study was to describe the brachiocephalic vein as an alternative site for elective ultrasound vascular cannulation in adults, and to compare it with the more commonly used internal jugular vein site in terms of procedural difficulties, first pass failure rate, overall failure rate, and safety...
April 19, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29682552/prefabricated-bar-system-for-immediate-loading-in-edentulous-patients-a-5-year-follow-up-prospective-longitudinal-study
#15
Enrico F Gherlone, Gianpaolo Sannino, Andrea Rapanelli, Roberto Crespi, Giorgio Gastaldi, Paolo Capparé
Objectives: The aim of this clinical study was to evaluate a new type of prefabricated bar system, supported by axial and tilted implants at 5-year follow-up. Materials and Methods: Twenty-nine consecutive participants (19 females, 10 males) (mean age 61.4 years), edentulous in one or both jaws, with severe atrophy of the posterior regions, were treated according to the All-on-four® protocol with immediately loaded axial (64) and tilted (64) implants supporting complete-arch screw-retained prostheses (12 maxillary, 20 mandibular) featuring a prefabricated bar as framework...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29682251/implant-abutment-connections-on-single-crowns-a-systematic-review
#16
REVIEW
F M Ceruso, P Barnaba, S Mazzoleni, L Ottria, M Gargari, A Zuccon, G Bruno, A DI Fiore
Different implant-abutment connections have been developed in the effort of reducing mechanical and biological failure. The most frequent complications are screw loosening, abutment or implant fracture and marginal bone loss due to overload and bacterial micro-leakage. Ideal connection should work as a one-piece implant avoiding the formation of a micro-gap at the implant-abutment interface. Different in vitro and in vivo researches have been published to compare the implant-abutment connections actually available: external hexagon, internal hexagon and conical finding different amount of micro-gap, micro-leakage and marginal bone loss...
October 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29682085/prostaglandin-e-2-produced-by-alginate-encapsulated-mesenchymal-stromal-cells-modulates-the-astrocyte-inflammatory-response
#17
Elizabeth C Stucky, Joshua Erndt-Marino, Rene S Schloss, Martin L Yarmush, David I Shreiber
Astroglia are well known for their role in propagating secondary injury following brain trauma. Modulation of this injury cascade, including inflammation, is essential to repair and recovery. Mesenchymal stromal cells (MSCs) have been demonstrated as trophic mediators in several models of secondary CNS injury, however, there has been varied success with the use of direct implantation due to a failure to persist at the injury site. To achieve sustained therapeutic benefit, we have encapsulated MSCs in alginate microspheres and evaluated the ability of these encapsulated MSCs to attenuate neuro-inflammation...
June 2017: Nano LIFE
https://www.readbyqxmd.com/read/29681957/mechanical-circulatory-support-is-effective-to-treat-pulmonary-hypertension-in-heart-transplant-candidates-disqualified-due-to-unacceptable-pulmonary-vascular-resistance
#18
Michał Zakliczyński, Jerzy Pacholewicz, Izabela Copik, Marcin Maruszewski, Tomasz Hrapkowicz, Roman Przybylski, Marian Zembala
Introduction: High pulmonary vascular resistance (PVR) in orthotopic heart transplantation (OHT) candidates is a risk factor of right ventricle failure after the procedure. However, the increase of PVR may be a consequence of the life-threatening deterioration of the left ventricle function. The use of mechanical circulatory support (MCS) seems to be the best solution, but it is reimbursed only in active OHT candidates. Aim: We performed a retrospective analysis of MCS effectiveness in maintaining PVR at values accepted for OHT...
March 2018: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29681715/can-intracytoplasmic-morphologically-selected-spermatozoa-injection-be-used-as-first-choice-of-treatment-for-severe-male-factor-infertility-patients
#19
Geeta Goswami, Meeta Sharma, Deepika Jugga, Devi M Gouri
Aim: This study was carried out to assess the outcome of the intracytoplasmic morphologically selected sperm injection (IMSI) technique compared with the previous failed intracytoplasmic sperm injection (ICSI) attempts in oligoasthenoteratozoospermia (OAT)/severe OAT (SOAT)/teratozoospermia patients. Setting: Institution-based, in vitro fertilization center. Study Design: It was a nonrandomized prospective study including 57 couples who had previous one or two ICSI failures (failure due to no implantation as embryos were transferred in these cycles and had no pregnancy) due to male factor...
January 2018: Journal of Human Reproductive Sciences
https://www.readbyqxmd.com/read/29681408/manta-versus-proglide-vascular-closure-devices-in-transfemoral-transcatheter-aortic-valve-implantation
#20
Fausto Biancari, Hannu Romppanen, Mikko Savontaus, Antti Siljander, Timo Mäkikallio, Olli-Pekka Piira, Jarkko Piuhola, Viivi Vilkki, Antti Ylitalo, Tuija Vasankari, Juhani K E Airaksinen, Matti Niemelä
BACKGROUND: The MANTA system is a novel vascular closure device (VCD) and its safety and efficacy were compared to the ProGlide VCD in patients undergoing transfemoral transcatheter aortic valve implantation (TAVI). METHODS: This is a retrospective study including 222 patients who underwent transfemoral TAVI at three Finnish University Hospitals. The MANTA VCD was used in 107 patients and their outcome was compared with that of 115 patients in whom the arterial access was closed with the ProGlide VCD...
April 14, 2018: International Journal of Cardiology
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