Raha M Dastgheyb, Alison S Buchholz, Kathryn C Fitzgerald, Yanxun Xu, Dionna W Williams, Gayle Springer, Kathryn Anastos, Deborah R Gustafson, Amanda B Spence, Adaora A Adimora, Drenna Waldrop, David E Vance, Joel Milam, Hector Bolivar, Kathleen M Weber, Norman J Haughey, Pauline M Maki, Leah H Rubin
Cognitive impairment remains frequent and heterogeneous in presentation and severity among virally suppressed (VS) women with HIV (WWH). We identified cognitive profiles among 929 VS-WWH and 717 HIV-uninfected women from 11 Women's Interagency HIV Study sites at their first neuropsychological (NP) test battery completion comprised of: Hopkins Verbal Learning Test-Revised, Trail Making, Symbol Digit Modalities, Grooved Pegboard, Stroop, Letter/Animal Fluency, and Letter-Number Sequencing. Using 17 NP performance metrics (T-scores), we used Kohonen self-organizing maps to identify patterns of high-dimensional data by mapping participants to similar nodes based on T-scores and clustering those nodes...
2021: Frontiers in Neurology