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Horst Sievert

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https://www.readbyqxmd.com/read/28684438/five-year-follow-up-after-transcatheter-aortic-valve-implantation-for-symptomatic-aortic-stenosis
#1
Ralf Zahn, Nicolas Werner, Ulrich Gerckens, Axel Linke, Horst Sievert, Philipp Kahlert, Rainer Hambrecht, Stefan Sack, Mohamed Abdel-Wahab, Ellen Hoffmann, Uwe Zeymer, Steffen Schneider
OBJECTIVES: Transcatheter aortic valve implantation (TAVI) has been implemented into the care of elderly patients suffering from severe symptomatic aortic stenosis. However, data on long-term follow-up are sparse and predictors of long-term mortality need to be evaluated to better select patients. Therefore, we aimed to analyse predictors of 5-year mortality after TAVI. METHODS: We analysed data from the German Transcatheter Aortic Valve Interventions-Registry. Each of the 27 participating hospitals agreed to include all consecutive TAVI patients at their institution...
July 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28606886/early-anticoagulation-drug-regimens-after-watchman-left-atrial-appendage-closure-safety-and-efficacy
#2
Martin W Bergmann, Timothy R Betts, Horst Sievert, Boris Schmidt, Evgeny Pokushalov, Stephan Kische, Thomas Schmitz, Felix Meincke, Kenneth M Stein, Lucas V Boersma, Hüseyin Ince
AIMS: While LAA closure has recently been incorporated in both European and US guidelines for stroke prevention, uncertainties regarding post-procedural drug therapy so far limit its adoption. METHODS AND RESULTS: 1005 patients were implanted with a WATCHMAN device in the prospective EWOLUTION study at 47 centers. 73.5% of the patients were deemed contraindicated for long-term OAC therapy. Here we report on 3-months data including the first follow-up TOE exam for 94% of the study population...
June 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28595859/left-atrial-appendage-occlusion-in-patients-with-atrial-fibrillation-and-previous-major-gastrointestinal-bleeding-from-the-amplatzer-cardiac-plug-multicenter-registry
#3
Mathieu Lempereur, Adel Aminian, Xavier Freixa, Sameer Gafoor, Samera Shakir, Heyder Omran, Sergio Berti, Gennaro Santoro, Joelle Kefer, Ulf Landmesser, Jens Erik Nielsen-Kudsk, Ignacio Cruz-Gonzalez, Prapa Kanagaratnam, Fabian Nietlispach, Reda Ibrahim, Horst Sievert, Wolfgang Schillinger, Jai-Wun Park, Steffen Gloekler, Apostolos Tzikas
History of major gastrointestinal (GI) bleeding may represent a frequent clinical indication for left atrial appendage occlusion (LAAO) in patients with non-valvular atrial fibrillation (AF). This study aims to investigate the procedural safety and long-term outcome of patients with previous major GI bleeding (MGIB) who underwent LAAO. Data from the Amplatzer Cardiac Plug multicenter registry on 1,047 patients were analyzed. Patients with previous MGIB as indication for LAAO were compared with patients without previous MGIB...
August 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28577840/efficacy-and-safety-of-left-atrial-appendage-closure-with-watchman-in-patients-with-or-without-contraindication-to-oral-anticoagulation-1-year-follow-up-outcome-data-of-the-ewolution-trial
#4
Lucas V Boersma, Hueseyin Ince, Stephan Kische, Evgeny Pokushalov, Thomas Schmitz, Boris Schmidt, Tommaso Gori, Felix Meincke, Alexey Vladimir Protopopov, Timothy Betts, David Foley, Horst Sievert, Patrizio Mazzone, Tom De Potter, Elisa Vireca, Kenneth Stein, Martin W Bergmann
BACKGROUND: Left atrial appendage (LAA) occlusion with WATCHMAN has emerged as viable alternative to vitamin K antagonists in randomized controlled trials. OBJECTIVE: EWOLUTION was designed to provide data in routine practice from a prospective multicenter registry. METHODS: A total of 1025 patients scheduled for a WATCHMAN implant were prospectively and sequentially enrolled at 47 centers. Indication for LAA closure was based on European Society of Cardiology guidelines...
May 31, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28577672/a-randomized-double-blind-trial-of-an-interventional-device-treatment-of-functional-mitral-regurgitation-in-patients-with-symptomatic-congestive-heart-failure-trial-design-of-the-reduce-fmr-study
#5
Steven L Goldberg, Ian Meredith, Thomas Marwick, Brian A Haluska, Janusz Lipiecki, Tomasz Siminiak, Nawzer Mehta, David M Kaye, Horst Sievert
The Carillon Mitral Contour System has been studied in 3 nonrandomized trials in patients with symptomatic congestive heart failure and functional mitral regurgitation. The REDUCE FMR study is a uniquely designed, double-blind trial evaluating the impact of the Carillon device on reducing regurgitant volume, as well as assessing the safety and clinical efficacy of this device. Carillon is a coronary sinus-based indirect annuloplasty device. Eligible patients undergo an invasive venogram to assess coronary sinus vein suitability for the Carillon device...
June 2017: American Heart Journal
https://www.readbyqxmd.com/read/28558502/six-month-results-from-the-initial-randomized-study-of-the-ranger-paclitaxel-coated-balloon
#6
Yvonne Bausback, Andrea Willfort-Ehringer, Horst Sievert, Volker Geist, Michael Lichtenberg, Costantino Del Giudice, Antoine Sauguet, Juan Diaz-Cartelle, Claudia Marx, Armin Ströbel, Ingolf Schult, Dierk Scheinert
PURPOSE: To evaluate the performance of the Ranger paclitaxel-coated balloon vs uncoated balloon angioplasty for femoropopliteal lesions. METHODS: Between January 2014 and October 2015, the prospective, randomized RANGER SFA study ( ClinicalTrials.gov identifier NCT02013193) enrolled 105 patients with symptomatic lower limb ischemia (Rutherford category 2-4) and stenotic lesions in the nonstented femoropopliteal segment at 10 European centers. Seventy-one patients (mean age 68±8 years; 53 men) were enrolled in the Ranger drug-coated balloon (DCB) arm and 34 patients (mean age 67±9 years; 23 men) were assigned to the control group...
May 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28555593/3d-printed-models-in-patients-with-coronary-artery-fistulae-anatomical-assessment-and-interventional-planning
#7
María de Las Nieves Velasco Forte, Nick Byrne, Israel Valverde Perez, Aaron Bell, Gorka Gómez-Ciriza, Thomas Krasemann, Horst Sievert, John Simpson, Kuberan Pushparajah, Reza Razavi, Shakeel Qureshi, Tarique Hussain
AIMS: Coronary artery fistulae represent one of the most challenging anatomical defects to define accurately. We investigated the additional benefit conferred by volume-rendering of tomographic images and 3D-printing for diagnosis and interventional planning. METHODS AND RESULTS: Four cases of coronary fistulae were considered for transcatheter closure. Multidetector computed tomography (3 cases) or Cardiac Magnetic Resonance (1 case) images were acquired and segmented using Mimics software...
May 30, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28521923/safety-and-efficacy-of-transcatheter-aortic-valve-replacement-in-the-treatment-of-pure-aortic-regurgitation-in-native-valves-and-failing-surgical-bioprostheses-results-from-an-international-registry-study
#8
Fadi J Sawaya, Marcus-André Deutsch, Moritz Seiffert, Sung-Han Yoon, Pablo Codner, Upul Wickramarachchi, Azeem Latib, A Sonia Petronio, Josep Rodés-Cabau, Maurizio Taramasso, Marco Spaziano, Johan Bosmans, Luigi Biasco, Darren Mylotte, Mikko Savontaus, Peter Gheeraert, Jason Chan, Troels H Jørgensen, Horst Sievert, Marco Mocetti, Thierry Lefèvre, Francesco Maisano, Antonio Mangieri, David Hildick-Smith, Ran Kornowski, Raj Makkar, Sabine Bleiziffer, Lars Søndergaard, Ole De Backer
OBJECTIVES: The aim of this study was to evaluate the use of transcatheter heart valves (THV) for the treatment of noncalcific pure native aortic valve regurgitation (NAVR) and failing bioprosthetic surgical heart valves (SHVs) with pure severe aortic regurgitation (AR). BACKGROUND: Limited data are available about the "off-label" use of transcatheter aortic valve replacement (TAVR) to treat pure severe AR. METHODS: The study population consisted of patients with pure severe AR treated by TAVR at 18 different centers...
May 22, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28475773/proceedings-from-the-2nd-european-clinical-consensus-conference-for-device-based-therapies-for-hypertension-state-of-the-art-and-considerations-for-the-future
#9
Felix Mahfoud, Roland E Schmieder, Michel Azizi, Atul Pathak, Horst Sievert, Costas Tsioufis, Thomas Zeller, Stefan Bertog, Peter J Blankestijn, Michael Böhm, Michel Burnier, Gilles Chatellier, Isabelle Durand Zaleski, Sebastian Ewen, Guido Grassi, Michael Joner, Sverre E Kjeldsen, Melvin D Lobo, Chaim Lotan, Thomas Felix Lüscher, Gianfranco Parati, Patrick Rossignol, Luis Ruilope, Faisal Sharif, Evert van Leeuwen, Massimo Volpe, Stephan Windecker, Adam Witkowski, William Wijns
No abstract text is available yet for this article.
May 5, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28394759/combined-mitro-aortic-pathology-impact-of-previous-aortic-valve-replacement-upon-outcomes-of-mitra-clip-therapy
#10
Giuseppe D'Ancona, Stephan Kische, Jochen Senges, Taoufik Ouarrak, Miriam Puls, Raffi Bekeredjian, Horst Sievert, Erdal Safak, Jasmin Ortak, Alper Öner, Wolfgang Schillinger, Hüseyin Ince
AIMS: To identify the impact of previous aortic valve replacement (AVR) in Mitra-Clip (MC) patients. METHODS AND RESULTS: Data from the German Transcatheter Mitral Valve Interventions (TRAMI) registry were analyzed in light of previous AVR by means of either standard AVR (SAVR) or transcatheter AVR (TAVR). Out of 791 MC, 68 (8.6%) had been submitted to AVR (68.4% SAVR and 31.6% TAVR). AVR group was significantly older (77.2±8.0 years vs. 75.1±8.6 years; p<0...
April 11, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28388746/-update-on-left-atrial-appendage-closure-2017
#11
Volker Schulze, Tobias Zeus, Horst Sievert
No abstract text is available yet for this article.
April 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28283511/independent-modular-filter-for-embolic-protection-in-carotid-stenting
#12
Dierk Scheinert, Bernhard Reimers, Alberto Cremonesi, Andrej Schmidt, Horst Sievert, Stefan Rohde, Joachim Schofer, Harald G Mudra, Marc Bosiers, Thomas Zeller, Andrea Pacchioni, Uri Rosenschein
BACKGROUND: Embolic protection during carotid artery stenting reduces the rate of thromboembolic events. The Wirion Embolic Protection System is used to deploy an independent distal filter using any 0.014″ guidewire. WISE study (Wirion Study Europe) evaluated the safety and performance of Wirion Embolic Protection System in patients undergoing carotid artery stenting. METHODS AND RESULTS: A prospective, multicenter, nonrandomized, open-label, single-arm study of carotid artery stenting in high surgical risk patients was performed...
March 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28215464/patients-with-intracranial-bleeding-and-atrial-fibrillation-treated-with-left-atrial-appendage-occlusion-results-from-the-amplatzer-cardiac-plug-registry
#13
Apostolos Tzikas, Xavier Freixa, Laura Llull, Sameer Gafoor, Samera Shakir, Heyder Omran, George Giannakoulas, Sergio Berti, Gennaro Santoro, Joelle Kefer, Adel Aminian, Steffen Gloekler, Ulf Landmesser, Jens Erik Nielsen-Kudsk, Ignacio Cruz-Gonzalez, Prapa Kanagaratnam, Fabian Nietlispach, Reda Ibrahim, Horst Sievert, Wolfgang Schillinger, Jai-Wun Park, Bernhard Meier, Haralampos Karvounis
BACKGROUND: In patients with non-valvular atrial fibrillation (NVAF), intracranial bleeding (ICB) constitutes a very challenging situation in which the rate of both ischemic and hemorrhagic events is increased. In these patients, left atrial appendage occlusion (LAAO) might represent a very valid alternative. OBJECTIVES: To investigate the procedural safety and long-term outcome of patients undergoing LAAO therapy due to previous ICB. METHODS: Data from the Amplatzer Cardiac Plug multicenter registry on 1047 consecutive patients were analyzed...
June 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28089998/first-clinical-experience-with-targeted-renal-nerve-demodulation-trend-1-using-a-neurotropic-agent-for-the-treatment-of-sympathetic-hypertension
#14
Nicholas Kipshidze, Horst Sievert, Michael H Wholey, Konstantin Kipiani, Vakhtang Kipiani, Tea Mukhuradze, Mark Wholey, Emily Stein, K T Venkateswara Rao
AIMS: To evaluate the feasibility and safety of a novel targeted neuromodulatory treatment for sympathetic hypertension involving a one-time local injection of neurotropic agents near renal nerves. METHODS AND RESULTS: Seven patients suffering from uncontrolled hypertension per ESH-ESC guidelines were treated using a single dose of NW2013, a neurotropic Na+/K+ ATPase antagonist. A microneedle catheter was used to administer 1.2 mL of NW2013 (0.6 mL per artery) to the perivascular space surrounding renal arteries using percutaneous endovascular procedures under fluoroscopic guidance...
January 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28089952/impact-of-tricuspid-valve-regurgitation-in-surgical-high-risk-patients-undergoing-mitraclip-implantation-results-from-the-trami-registry
#15
Daniel Kalbacher, Ulrich Schäfer, R Stephan von Bardeleben, Christine S Zuern, Raffi Bekeredjian, Taoufik Ouarrak, Horst Sievert, Georg Nickenig, Peter Boekstegers, Jochen Senges, Wolfgang Schillinger, Edith Lubos
AIMS: We sought to assess the impact of tricuspid regurgitation (TR) severity on patient outcome in a collective with relevant mitral regurgitation undergoing MitraClip implantation.. METHODS AND RESULTS: From August 2010 to July 2013, 766 patients (age 75.3±8.5 years, 61% male, median EuroSCORE 24.3%±18.4) were prospectively enrolled in the TRAMI registry and stratified by echocardiography into no/mild, moderate and severe TR. Overall, the mean number of implanted MitraClips was higher in patients with severe TR but increasing TR severity was not associated with procedural success...
February 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/27970251/tct-86-early-experience-with-the-trialign-system-for-transcatheter-tricuspid-valve-repair-a-multicenter-experience
#16
Ermela Yzeiraj, Horst Sievert, Georg Nickenig, Azeem Latib, Rebecca Hahn, Joachim Schofer
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970217/tct-826-prospective-single-center-first-in-human-fih-clinical-trial-to-evaluate-the-safety-and-effectiveness-of-a-septal-occluder-with-bioresorbable-framework-in-patients-with-clinically-significant-atrial-septum-defect-asd-or-patent-foramen-ovale-pfo
#17
Björn Söderberg, Laura Vaskelyte, Sameer Gafoor, Ilona Hofmann, Andreas Mellmann, Jerome Bernhard, Horst Sievert
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970208/tct-815-clinical-benefits-of-less-invasive-device-based-left-ventricular-reconstruction-a-hybrid-option-for-patients-with-ischemic-cardiomyopathy
#18
Christoph Schmitz, Mauri Biffi, Horst Sievert, Petr Neuzil, Salvatore Brugaletta, Christian Frerker, Azfar Zaman, Luigi Fiocca, Louis Labrousse, Lon Annest
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970018/tct-640-percutaneous-mitral-valve-annuloplasty-patients-with-minimal-acute-reduction-in-mitral-regurgitation-improve-long-term-from-the-titan-ii-trial
#19
Horst Sievert, Steven Goldberg, Tomasz Siminiak, Hubertus Degen, Janusz Lipiecki, Michael Haude
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970014/tct-639-the-impact-of-mitral-regurgitation-severity-on-efficacy-of-percutaneous-mitral-valve-annuloplasty-in-functional-mitral-regurgitation
#20
Horst Sievert, Michael Haude, Hubertus Degen, Janusz Lipiecki, Steven Goldberg, Tomasz Siminiak
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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