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https://www.readbyqxmd.com/read/28230903/-evidence-based-medicine-in-eating-disorders-research-the-problem-of-confetti-p-values
#1
Helena Chmura Kraemer
Eating disorders hold a unique place among mental health disorders, in that salient symptoms can be objectively observed and measured rather than determined only from patient interviews or subjective evaluations. Because of this measurement advantage alone, evidence-based medicine would be expected there to make the most rapid strides. However, conclusions in Eating Disorders research, as in all medical research literature, often continue to be misleading or ambiguous. One major and long-known source of such problems is the misuse and misinterpretation of "statistical significance", with "p values" strewn throughout research papers like so much confetti, a problem that has become systemic, that is, enforced, rather than corrected, by the peer-review system...
February 23, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28230650/acr-appropriateness-criteria%C3%A2-resectable-pancreatic-cancer
#2
William E Jones, W Waren Suh, May Abdel-Wahab, Ross A Abrams, Nilofer Azad, Prajnan Das, Jadranka Dragovic, Karyn A Goodman, Salma K Jabbour, Andre A Konski, Albert C Koong, Rachit Kumar, Percy Lee, Timothy M Pawlik, William Small, Joseph M Herman
Management of resectable pancreatic adenocarcinoma continues to present a challenge due to a paucity of high-quality randomized studies. Administration of adjuvant chemotherapy is widely accepted due to the high risk of systemic spread associated with pancreatic adenocarcinoma, but the role of radiation therapy is less clear. This paper reviews literature associated with resectable pancreatic cancer to include prognostic factors to aid in the selection of patients appropriate for adjuvant therapies. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel...
February 22, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28230267/the-economic-impact-of-space-weather-where-do-we-stand
#3
J P Eastwood, E Biffis, M A Hapgood, L Green, M M Bisi, R D Bentley, R Wicks, L-A McKinnell, M Gibbs, C Burnett
Space weather describes the way in which the Sun, and conditions in space more generally, impact human activity and technology both in space and on the ground. It is now well understood that space weather represents a significant threat to infrastructure resilience, and is a source of risk that is wide-ranging in its impact and the pathways by which this impact may occur. Although space weather is growing rapidly as a field, work rigorously assessing the overall economic cost of space weather appears to be in its infancy...
February 23, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28230115/peer-review-award-bonus-points-to-motivate-reviewers
#4
David Gurwitz
No abstract text is available yet for this article.
February 22, 2017: Nature
https://www.readbyqxmd.com/read/28228565/a-dedicated-scholarly-research-program-in-an-adult-and-pediatric-neurology-residency-program
#5
Matthew S Robbins, Sheryl R Haut, Richard B Lipton, Mark J Milstein, Lenore C Ocava, Karen Ballaban-Gil, Solomon L Moshé, Mark F Mehler
OBJECTIVE: To describe and assess the effectiveness of a formal scholarly activity program for a highly integrated adult and pediatric neurology residency program. METHODS: Starting in 2011, all graduating residents were required to complete at least one form of scholarly activity broadly defined to include peer-reviewed publications or presentations at scientific meetings of formally mentored projects. The scholarly activity program was administered by the associate residency training director and included an expanded journal club, guided mentorship, a required grand rounds platform presentation, and annual awards for the most scholarly and seminal research findings...
February 22, 2017: Neurology
https://www.readbyqxmd.com/read/28227482/assessing-app-quality-through-expert-peer-review-a-case-study-from-the-gray-matters-study
#6
Phillip J Hartin, Ian Cleland, Chris D Nugent, Sally I McClean, JoAnn Tschanz, Christine Clark, Maria C Norton, Phillip J Hartin, Ian Cleland, Chris D Nugent, Sally I McClean, JoAnn Tschanz, Christine Clark, Maria C Norton, JoAnn Tschanz, Christine Clark, Ian Cleland, Maria C Norton, Sally I McClean, Chris D Nugent, Phillip J Hartin
Health apps focused on inciting behavior change are becoming increasingly popular. Nevertheless, many lack underlying evidence base, scientific credibility and have limited clinical effectiveness. It is therefore important that apps are well-informed, scientifically credible, peer reviewed and evidence based. This paper presents the use of the Mobile App Rating Scale (MARS) to assess the quality of the Grey Matters app, a cross platform app to deliver health education material and track behavior change across multi-domains with the aim of reducing the risk of developing Alzheimer's disease...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226418/omalizumab-for-the-treatment-of-chronic-idiopathic-urticaria-systematic-review-of-the-literature
#7
Alessandro Tonacci, Lucia Billeci, Giovanni Pioggia, Michele Navarra, Sebastiano Gangemi
Omalizumab is recombinant humanized monoclonal antibody to immunoglobulin E. Guidelines for the treatment of chronic idiopathic urticaria (also known as chronic spontaneous urticaria) recommend the use of omalizumab as third-line therapy in addition to high doses of histamine receptor type 1 (H1 ) antihistamines when they are unsuccessful as first- and second-line therapy. We performed a systematic review of the literature to identify studies that evaluated the efficacy of omalizumab for the treatment of chronic idiopathic urticaria, both in controlled and real-world settings, to assess its potential role as a preferred therapy...
February 22, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28226416/the-contribution-of-the-emergency-department-to-opioid-pain-reliever-misuse-and-diversion-a-critical-review
#8
REVIEW
Tatyana Lyapustina, Renan Castillo, Elise Omaki, Wendy Shields, Eileen McDonald, Richard Rothman, Andrea Gielen
Prescription opioid pain reliever (OPR) misuse and diversion is an important and growing public health problem in the United States that is responsible for significant morbidity and mortality. Emergency physicians are among the top prescribers of OPRs, yet the relative contribution of emergency department (ED) OPR prescriptions to the overall opioid abuse epidemic remains unclear. This study critically reviews seven peer-reviewed studies that specifically identified the ED as a source of OPRs. Of the OPRs prescribed in the ED, approximately 10% are associated with indicators of inappropriate prescribing, and approximately 42% may ultimately be misused; of the OPRs that are diverted, approximately 10% originate from an ED prescription...
February 22, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28225466/the-use-of-social-media-in-graduate-medical-education-a-systematic-review
#9
Madeline Sterling, Peggy Leung, Drew Wright, Tara F Bishop
PURPOSE: Despite the growing presence of social media in graduate medical education (GME), few studies have attempted to characterize their effect on residents and their training. The authors conducted a systematic review of the peer-reviewed literature to understand the effect of social media on resident (1) education, (2) recruitment, and (3) professionalism. METHOD: The authors identified English-language peer-reviewed articles published through November 2015 using Medline, Embase, Cochrane, PubMed, Scopus, and ERIC...
February 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28225361/to-ear-and-hearing-peer-reviewers-thank-you
#10
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28223373/nicu-based-interventions-to-reduce-maternal-depressive-and-anxiety-symptoms-a-meta-analysis
#11
REVIEW
Tamar Mendelson, Fallon Cluxton-Keller, Genevieve C Vullo, S Darius Tandon, Sassan Noazin
CONTEXT: Parents whose infants are being treated in the NICU are at high risk for depression and anxiety, with negative implications for parenting and infant development. OBJECTIVE: We conducted a systematic review and meta-analysis of NICU-based interventions to reduce maternal depressive or anxiety symptoms. DATA SOURCES: PubMed, Embase, PsychInfo, Cochrane, and CINAHL were searched for relevant studies. Reference lists from selected studies were reviewed...
February 21, 2017: Pediatrics
https://www.readbyqxmd.com/read/28222873/influence-of-abutment-tooth-geometry-on-the-accuracy-of%C3%A2-conventional-and-digital-methods-of-obtaining-dental%C3%A2-impressions
#12
Jeison B Carbajal Mejía, Kazumichi Wakabayashi, Takashi Nakamura, Hirofumi Yatani
STATEMENT OF PROBLEM: Direct (intraoral) and indirect (desktop) digital scanning can record abutment tooth preparations despite their geometry. However, little peer-reviewed information is available regarding the influence of abutment tooth geometry on the accuracy of digital methods of obtaining dental impressions. PURPOSE: The purpose of this in vitro study was to evaluate the influence of abutment tooth geometry on the accuracy of conventional and digital methods of obtaining dental impressions in terms of trueness and precision...
February 17, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28222828/metabolic-consequences-of-obesity-and-insulin-resistance-in-polycystic-ovary-syndrome-diagnostic-and-methodological-challenges
#13
Yvonne M Jeanes, Sue Reeves
Women with polycystic ovary syndrome (PCOS) have a considerable risk of metabolic dysfunction. This review aims to present contemporary knowledge on obesity, insulin resistance and PCOS with emphasis on the diagnostic and methodological challenges encountered in research and clinical practice. Variable diagnostic criteria for PCOS and associated phenotypes are frequently published. Targeted searches were conducted to identify all available data concerning the association of obesity and insulin resistance with PCOS up to September 2016...
February 22, 2017: Nutrition Research Reviews
https://www.readbyqxmd.com/read/28222812/prevalence-and-risk-factors-for-post-investigation-colorectal-cancer-interval-cancer-after-computed-tomographic-colonography-protocol-for-a-systematic-review
#14
Andrew A Plumb, Anu Obaro, Thomas Fanshawe, Ulysses S Torres, Rachel Baldwin-Cleland, Steve Halligan, David Burling
BACKGROUND: Colorectal cancer (CRC) is a common and important disease. There are different tests for diagnosis, one of which is computed tomographic colonography (CTC). No test is perfect, and patients with normal CTC may subsequently develop CRC (either because it was overlooked originally, or because it has developed in the interim). This is termed post-investigation colorectal cancer (PICRC) or "interval cancer". How frequently this occurs after CTC is not known. The purpose of this systematic review and meta-analysis is to use the primary literature to estimate the PICRC rate after CTC, and explore associated factors...
February 21, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28222653/who-is-a-community-health-worker-a-systematic-review-of-definitions
#15
Abimbola Olaniran, Helen Smith, Regine Unkels, Sarah Bar-Zeev, Nynke van den Broek
BACKGROUND: Community health workers (CHWs) can play vital roles in increasing coverage of basic health services. However, there is a need for a systematic categorisation of CHWs that will aid common understanding among policy makers, programme planners, and researchers. OBJECTIVE: To identify the common themes in the definitions and descriptions of CHWs that will aid delineation within this cadre and distinguish CHWs from other healthcare providers. DESIGN: A systematic review of peer-reviewed papers and grey literature...
2017: Global Health Action
https://www.readbyqxmd.com/read/28221008/peer-review-an-appreciation
#16
EDITORIAL
Lin Perry
No abstract text is available yet for this article.
February 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28220926/genetic-testing-for-autism-spectrum-disorder-is-lacking-evidence-of-cost-effectiveness-a-systematic-review
#17
Andreas Ziegler, Wolfgang Rudolph-Rothfeld, Reinhard Vonthein
BACKGROUND: Autism Spectrum Disorder (ASD) is a highly heritable neural development disorder characterized by social impairment. The earlier the diagnosis is made, the higher are the chances of obtaining relief of symptoms. A very early diagnosis uses molecular genetic tests, which are also offered commercially. OBJECTIVE: Systematic review of the economic impact of genetic tests in ASD. METHODS: We performed a systematic search of databases Pubmed, Medline, Cochrane, Econlit and the NHS Center for Reviews and Dissemination for articles in English and German from January 1, 2000 to December 31, 2015...
February 21, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28219961/protocol-for-the-development-of-a-core-domain-set-for-hidradenitis-suppurativa-trial-outcomes
#18
Linnea Thorlacius, John R Ingram, Amit Garg, Bente Villumsen, Solveig Esmann, Joslyn S Kirby, Alice B Gottlieb, Joseph F Merola, Robert Dellavalle, Robin Christensen, Gregor B E Jemec
INTRODUCTION: Randomised controlled trials (RCTs) should have well-defined primary and secondary outcomes to answer questions generated by the main hypotheses. However, for the chronic, inflammatory skin disease hidradenitis suppurativa (HS), the reported outcome measures are numerous and diverse. A recent systematic review found a total of 30 outcome measure instruments in 12 RCTs. This use of a broad range of outcome measures can increase difficulties in interpretation and comparison of results and may potentially obstruct appropriate evidence synthesis by causing reporting bias...
February 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28219417/documenting-research-with-transgender-and-gender%C3%A2-diverse-people-protocol-for-an-evidence-map-and-thematic-analysis
#19
Zack Marshall, Vivian Welch, James Thomas, Fern Brunger, Michelle Swab, Ian Shemilt, Chris Kaposy
BACKGROUND: There is limited information about how transgender, gender diverse, and Two-Spirit (trans) people have been represented and studied by researchers. The objectives of this study are to (1) map and describe trans research in the social sciences, sciences, humanities, health, education, and business, (2) identify evidence gaps and opportunities for more responsible research with trans people, (3) assess the use of text mining for study identification, and (4) increase access to trans research for key stakeholders through the creation of a web-based evidence map...
February 20, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28219081/current-methods-of-evaluating-speech-language-outcomes-for-preschoolers-with-communication-disorders-a-scoping-review-using-the-icf-cy
#20
Barbara Jane Cunningham, Karla N Washington, Amanda Binns, Katelyn Rolfe, Bernadette Robertson, Peter Rosenbaum
Purpose: The purpose of this scoping review was to identify current measures used to evaluate speech-language outcomes for preschoolers with communication disorders within the framework of the International Classification of Functioning, Disability and Health-Children and Youth Version (ICF-CY; World Health Organization, 2007). Method: The review involved 5 phases outlined by Arksey and O'Malley (2005) and further developed by Levac, Colquhoun, and O'Brien (2010): (a) articulating the research question; (b) identifying relevant studies; (c) selecting studies; (d) charting the data; and (e) collating, summarizing, and reporting the results...
February 1, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
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