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https://www.readbyqxmd.com/read/29666141/examining-the-effectiveness-of-consuming-flour-made-from-agronomically-biofortified-wheat-zincol-2016-nr-421-for-improving-zn-status-in-women-in-a-low-resource-setting-in-pakistan-study-protocol-for-a-randomised-double-blind-controlled-cross-over-trial-bizifed
#1
Nicola M Lowe, Muhammad Jaffar Khan, Martin R Broadley, Munir H Zia, Harry J McArdle, Edward J M Joy, Heather Ohly, Babar Shahzad, Ubaid Ullah, Gul Kabana, Rashid Medhi, Mukhtiar Zaman Afridi
INTRODUCTION: Dietary zinc (Zn) deficiency is a global problem, particularly in low-income and middle-income countries where access to rich, animal-source foods of Zn is limited due to poverty. In Pakistan, Zn deficiency affects over 40% of the adult female population, resulting in suboptimal immune status and increased likelihood of complications during pregnancy. METHODS AND ANALYSIS: We are conducting a double-blind, randomised controlled feeding study with cross-over design in a low-resource setting in Pakistan...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29666139/last-year-of-life-study-cologne-lyol-c-protocol-for-a-cross-sectional-mixed-methods-study-to-examine-care-trajectories-and-transitions-in-the-last-year-of-life-until-death
#2
Julia Strupp, Gloria Hanke, Nicolas Schippel, Holger Pfaff, Ute Karbach, Christian Rietz, Raymond Voltz
INTRODUCTION: The last year of life constitutes a particularly vulnerable phase for patients, involving nearly all health and social care structures. Yet, little scientific evidence is available that provides insight into the trajectories including the number and types of care setting transitions, transitions into palliative care and the dying phase. Only few studies have focused on difficulties associated with having to move between health and social care settings in the last year of life, although patients face a significant risk of adverse events...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29666137/the-french-prospective-multisite-registry-on-sudden-unexpected-infant-death-omin-rationale-and-study-protocol
#3
Karine Levieux, Hugues Patural, Inge Harrewijn, Elisabeth Briand Huchet, Sophie de Visme, Géraldine Gallot, Martin Chalumeau, Christèle Gras Le Guen, Matthieu Hanf
INTRODUCTION: Even after 'back-to-sleep' campaigns, sudden unexpected infant death (SUID) continues to be the leading cause of death for infants 1 month to 1 year old in developed countries, with devastating social, psychological and legal implications for families. To sustainably tackle this problem and decrease the number of SUIDs, a French SUID registry was initiated in 2015 to (1) inform prevention with standardised data, (2) understand the mechanisms leading to SUID and the contribution of the already known or newly suggested risk factors and (3) gather a multidisciplinary group of experts to coordinate and develop innovative and urgent research in the SUID area...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29666135/study-protocol-for-the-saron-trial-a-multicentre-randomised-controlled-phase-iii-trial-comparing-the-addition-of-stereotactic-ablative-radiotherapy-and-radical-radiotherapy-with-standard-chemotherapy-alone-for-oligometastatic-non-small-cell-lung-cancer
#4
John Conibear, Brendan Chia, Yenting Ngai, Andrew Tom Bates, Nicholas Counsell, Rushil Patel, David Eaton, Corinne Faivre-Finn, John Fenwick, Martin Forster, Gerard G Hanna, Susan Harden, Philip Mayles, Syed Moinuddin, David Landau
INTRODUCTION: Following growing evidence to support the safety, local control (LC) and potential improvement in overall survival (OS) in patients with oligometastatic non-small cell lung cancer (NSCLC) that have been treated with local ablative therapy such as stereotactic ablative radiotherapy (SABR) and stereotactic radiosurgery (SRS), we initiate the SARON trial to investigate the impact and feasibility of adding SABR/SRS and radical radiotherapy (RRT) following standard chemotherapy on OS...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29666134/adoption-of-a-novel-surgical-innovation-into-clinical-practice-protocol-for-a-qualitative-systematic-review-examining-surgeon-views
#5
Thomas L Lewis, Hugh N Furness, George W Miller, Nicholas Parsons, Kate Seers, Martin Underwood, Andrew J Metcalfe
INTRODUCTION: Efficient adoption of clinically effective novel surgical innovations has great potential benefits for patients. Factors affecting the adoption of surgical innovation are not well understood and proposed models of adoption do not accurately correlate with historical evidence. This protocol is for a systematic review that aims to identify the qualitative evidence relating to surgeon views regarding the adoption of novel surgical innovation into clinical practice. METHODS AND ANALYSIS: A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidance will be performed...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29665713/a-clockwork-wikipedia-from-a-broad-perspective-to-a-case-study
#6
Omer Benjakob, Rona Aviram
While research has shown that scientists use Wikipedia and that scientific content on Wikipedia ramifies back into scientific literature, many questions remain on how the two sides interact and through what paradigm this dynamic may be best understood. Using the circadian clock field as a case study, we discuss this scientific field's representation on Wikipedia. We traced the changes made to the articles for "Circadian clock" and "Circadian rhythm" and reviewed the debates that informed them over a span of a decade, using Wikipedia's native and third-party tools...
April 1, 2018: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/29665700/organizational-response-to-known-medical-errors-does-peer-review-protection-impede-improvement
#7
William J Wenner, Sung W Choi
No abstract text is available yet for this article.
April 1, 2018: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/29664356/2016-annual-report-from-the-italian-vats-group
#8
Piergiorgio Solli, Luca Bertolaccini, Andrea Droghetti, Alessandro Bertani, Alessandro Gonfiotti, Mario Nosotti, Marcello Migliore, Roberto Crisci, Italian Vats Group
This report highlights the results of the Italian video-assisted thoracoscopic surgery (VATS) Group, launched in mid 2013, which now has a website and an established database with over 4000 VATS lobectomy cases recruited from 67 thoracic surgery units across Italy. The year 2016 has been crucial for the following steps: inclusion of a dedicated biostatistician and a 'Survey Analysis & Data Quality Check'; the First Consensus Meeting with statements consequently adopted as Recommendations for the Italian Thoracic Surgery Society and published in a peer-reviewed journal; two papers published under the logo Italian VATS Group and seven abstracts accepted at annual international meetings (European Society of Thoracic Surgeons, European Association of Cardio-Thoracic Surgeons, European Lung Cancer Conference and European Respiratory Society); the institution of a Master Course on VATS lobectomy; the partnership with AME Publishing Company...
March 2018: Future Oncology
https://www.readbyqxmd.com/read/29664324/the-work-programme-of-eurados-on-internal-and-external-dosimetry
#9
W Rühm, J F Bottollier-Depois, P Gilvin, R Harrison, Ž Knežević, M A Lopez, R Tanner, A Vargas, C Woda
Since the early 1980s, the European Radiation Dosimetry Group (EURADOS) has been maintaining a network of institutions interested in the dosimetry of ionising radiation. As of 2017, this network includes more than 70 institutions (research centres, dosimetry services, university institutes, etc.), and the EURADOS database lists more than 500 scientists who contribute to the EURADOS mission, which is to promote research and technical development in dosimetry and its implementation into practice, and to contribute to harmonisation of dosimetry in Europe and its conformance with international practices...
January 1, 2018: Annals of the ICRP
https://www.readbyqxmd.com/read/29664134/intra-specific-variation-in-social-organization-of-strepsirrhines
#10
REVIEW
Paul Agnani, Cécile Kauffmann, Loren D Hayes, Carsten Schradin
Strepsirrhines, that is, lemurs, galagos, and lorises, are considered basal primates, making them important to understand the evolution of primate sociality. Apart from some lemurs, they are nocturnal and solitary living, though the view of their sociality nature has changed with field studies being completed. We conducted a review of the primary literature about the social organization (group composition) of strepsirrhines, with the aim to determine whether intra-specific variation in social organization (IVSO) occurs and to determine how many species are pair-living, group-living, or solitary living...
April 17, 2018: American Journal of Primatology
https://www.readbyqxmd.com/read/29663830/is-there-a-role-for-postoperative-physiotherapy-in-degenerative-cervical-myelopathy-a-systematic-review
#11
Abdul Badran, Benjamin M Davies, Heidi-Marie Bailey, Sukhvinder Kalsi-Ryan, Mark Rn Kotter
OBJECTIVE: To review peer-reviewed literature relating to postoperative physiotherapy for degenerative cervical myelopathy (DCM), to determine efficacy in improving clinical outcome and recovery. DATA SOURCES: MEDLINE, EMBASE, CENTRAL, PEDro, ISRCTN registry, WHO ICTRP and Clinicaltrials.gov . References and citations of relevant articles were searched. METHODS: A systematic search was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (PROSPERO CRD42016039511) from the origins of the databases till 15 February 2018...
April 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29663277/peer-review-of-abstracts-submitted-to-an-internal-medicine-national-meeting-is-it-a-predictor-of-future-publication
#12
Cecilia Scholcoff, Payal Sanghani, Wilkins Jackson, Heidi M Egloff, Adam P Sawatsky, Jeffrey L Jackson
No abstract text is available yet for this article.
April 16, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29662622/quantitative-parameters-in-dynamic-contrast-enhanced-magnetic-resonance-imaging-for-the-detection-and-characterization-of-prostate-cancer
#13
Cheng Wei, Bowen Jin, Magdalena Szewczyk-Bieda, Stephen Gandy, Stephen Lang, Yilong Zhang, Zhihong Huang, Ghulam Nabi
Objectives: to assess the diagnostic accuracy of quantitative parameters of DCE-MRI in multi-parametric MRI (mpMRI) in comparison to the histopathology (including Gleason grade) of prostate cancer. Patients and methods: 150 men with suspected prostate cancer (abnormal digital rectum examination and or elevated prostate-specific antigen) received pre-biopsy 3T mpMRI and were recruited into peer-reviewed, protocol-based prospective study. The DCE-MRI quantitative parameters ( Ktrans (influx transfer constant) and kep (efflux rate constant)) of the cancerous and normal areas were recorded using four different kinetic models employing Olea Sphere (Olea Medical, La Ciotat, France)...
March 23, 2018: Oncotarget
https://www.readbyqxmd.com/read/29662521/evaluating-training-programs-for-primary-care-providers-in-child-adolescent-mental-health-in-canada-a-systematic-review
#14
Sandra Gotovac, Stacey Espinet, Reza Naqvi, Lorelei Lingard, Margaret Steele
Introduction: The need for child/adolescent mental health care in Canada is growing. Primary care can play a key role in filling this gap, yet most providers feel they do not have adequate training. This paper reviews the Canadian literature on capacity building programs in child and adolescent psychiatry for primary care providers, to examine how these programs are being implemented and evaluated to contribute to evidence-based initiatives. Methods: A systematic literature review of peer-reviewed published articles of capacity building initiatives in child/adolescent mental health care for primary care practitioners that have been implemented in Canada...
April 2018: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29661689/cardiometabolic-risk-and-female-sexuality-part-ii-understanding-and-overcoming-gender-differences-the-key-role-of-an-adequate-methodological-approach
#15
REVIEW
Elisa Maseroli, Irene Scavello, Linda Vignozzi
INTRODUCTION: Although basic science and clinical research indicate that the vascular physiopathology of male and female sexual dysfunction (FSD) is similar, to date the association between FSD and cardiovascular (CV) diseases has been only marginally explored. AIM: To discuss the potential reasons for differences in the role of CV diseases and risk factors in sexual function in women vs men in the 2nd part of a 2-part review. METHODS: A thorough literature search of peer-reviewed publications on the topic was performed using the PubMed database...
April 13, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29661584/strategies-for-increasing-uptake-of-vaccination-in-pregnancy-in-high-income-countries-a-systematic-review
#16
REVIEW
Kate Alexandra Bisset, Pauline Paterson
INTRODUCTION: Vaccination in pregnancy is an effective method to protect against disease for the pregnant woman, foetus and new born infant. In England, it is recommended that pregnant women are vaccinated against pertussis and influenza. Improvement in the uptake of both pertussis and influenza vaccination among pregnant women is needed to prevent morbidity and mortality for both the pregnant women and unborn child. AIM: To identify effective strategies in increasing the uptake of vaccination in pregnancy in high-income countries and to make recommendations for England...
April 13, 2018: Vaccine
https://www.readbyqxmd.com/read/29661009/to-blind-or-not-to-blind-the-search-for-a-perfect-peer-review-methodology
#17
Francesca Lake
No abstract text is available yet for this article.
April 2018: BioTechniques
https://www.readbyqxmd.com/read/29659780/health-outcomes-for-clients-of-needle-and-syringe-programs-in-prisons
#18
Jeffrey V Lazarus, Kelly Safreed-Harmon, Kristina L Hetherington, Daniel J Bromberg, Denise Ocampo, Niels Graf, Anna Dichtl, Heino Stöver, Hans Wolff
High levels of drug dependence have been observed in the prison population globally, and the sharing of injecting drug equipment in prisons has contributed to higher prevalence of bloodborne diseases in prisoners than in the general population. Few prison needle and syringe programs (PNSPs) exist. We conducted a systematic review to assess evidence regarding health outcomes of PNSPs. We searched peer-reviewed databases for data relating to needle and syringe programs in prisons. The search methodology was conducted in accordance with accepted guidelines...
April 12, 2018: Epidemiologic Reviews
https://www.readbyqxmd.com/read/29659573/whole-body-iron-transport-and-metabolism-mechanistic-multi-scale-model-to-improve-treatment-of-anemia-in-chronic-kidney-disease
#19
Joydeep Sarkar, Alka A Potdar, Gerald M Saidel
Iron plays vital roles in the human body including enzymatic processes, oxygen-transport via hemoglobin and immune response. Iron metabolism is characterized by ~95% recycling and minor replenishment through diet. Anemia of chronic kidney disease (CKD) is characterized by a lack of synthesis of erythropoietin leading to reduced red blood cell (RBC) formation and aberrant iron recycling. Treatment of CKD anemia aims to normalize RBC count and serum hemoglobin. Clinically, the various fluxes of iron transport and accumulation are not measured so that changes during disease (e...
April 16, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29658851/an-eye-on-vision-five-questions-about-vision-screening-and-eye-health
#20
P Kay Nottingham Chaplin, Kira Baldonado, Geoffrey E Bradford, Susan Cotter, Bruce Moore
Current evidence-based and best-practice vision screening and eye health approaches, tools, and procedures are the result of revised national guidelines in the past 3 years and advances in research during the past 18 years. In providing answers to the five questions in this article, the National Center for Children's Vision and Eye Health at Prevent Blindness used published, peer-reviewed research; vision screening and eye health national guidelines; and consensus-based best practices from eye care professionals and public health experts...
May 2018: NASN School Nurse
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