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https://www.readbyqxmd.com/read/29924376/immediate-improvement-of-left-ventricular-mechanics-following-transcatheter-aortic-valve-replacement
#1
Vanesa Cristina Lozano Granero, Sara Fernández Santos, Covadonga Fernández-Golfín, María Plaza Martín, Jesús María de la Hera Galarza, Francesco Fulvio Faletra, Martin J Swaans, Teresa López-Fernández, Dolores Mesa, Giovanni La Canna, Tomás Echeverría García, Gilbert Habib, Amparo Martíne Monzonís, José Luis Zamorano Gómez
BACKGROUND: Left ventricular (LV) mechanics are impaired in patients with severe aortic stenosis (AS). Transcatheter aortic valve replacement (TAVR) has become a widespread technique for patients with severe AS considered inoperable or high risk for traditional open-surgery. This procedure could have a positive impact in LV mechanics. The aim of this study was to evaluate the immediate effect of TAVR on LV function recovery, as assessed by myocardial deformation parameters. METHODS: One-hundred twelve consecutive patients (81...
June 20, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29914305/early-detection-strain-strain-rate-and-time-to-strain-strain-rate-abnormalities-for-left-atrial-mechanical-function-in-hypertensive-patients
#2
Ahmet Karakurt, Cennet Yildiz, Abdülmelik Yildiz, Yavuz Karabağ, Metin Çağdaş, İbrahim Rencüzoğulları, İnanç Artaç, Doğan İliş
OBJECTIVE: To evaluate left atrial (LA) deformation parameters strain (S)/strain rate (SR) and time to peak S/SR obtained by two-dimensional speckle tracking echocardiography (2D-STE) in patients with hypertension for three LA mechanical phases and to compare them with the same indices in the control subjects. METHODS: Fifty-five patients with hypertension (HT) and 29 healthy controls were included in the study. All patients had normal LA poster-anterior diameter, LA and left ventricular ejection fractions (LVEF >50%) in two-dimensional echocardiography (2-DE)...
June 18, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29914297/variability-of-longitudinal-strain-measurements-levelling-the-playing-field
#3
Oana Mirea, Oana Maria Corîci, Mihaela Berceanu, Ionuţ Donoiu, Constantin Militaru, Octavian Istratoaie
Speckle tracking echocardiography offers a unique opportunity to evaluate myocardial function, and global longitudinal strain (GLS) is currently recommended as a measurement of global left ventricular function. To facilitate clinical applicability of the method, collective efforts have been made to standardise strain measurements and to raise awareness of the potential sources of variability. The purpose of this review is to familiarise the reader with the most common sources of variability of longitudinal strain measurements and detail the possible measures to increase the accuracy and reproducibility of strain parameters...
June 18, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29912019/left-atrial-strain-measurement-and-clinical-application
#4
Jonathan Buggey, Brian D Hoit
PURPOSE OF REVIEW: To summarize recent literature on the use of left atrial strain in the diagnosis and management of patients with heart failure. RECENT FINDINGS: Left atrial dysfunction is a hallmark of diastolic dysfunction and heart failure, in particular, heart failure with preserved ejection fraction (HFpEF). Recently, myocardial deformation analysis via strain and strain rate measurements have been applied to the left atrium. These measurements have been shown to aid in the diagnosis of heart failure and be accurate predictors of cardiac pressures, diastolic dysfunction, exercise performance, and clinical outcomes such as cardiac hospitalizations and mortality...
June 14, 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29909156/high-dose-influenza-vaccine-to-reduce-clinical-outcomes-in-high-risk-cardiovascular-patients-rationale-and-design-of-the-invested-trial
#5
Orly Vardeny, Jacob A Udell, Jacob Joseph, Michael E Farkouh, Adrian F Hernandez, Alison J McGeer, H Keipp Talbot, Deepak L Bhatt, Christopher P Cannon, Shaun G Goodman, Inder Anand, David L DeMets, Jon Temte, Janet Wittes, Kristin Nichol, Clyde W Yancy, J Michael Gaziano, Lawton S Cooper, KyungMann Kim, Scott D Solomon
BACKGROUND: Influenza leads to significant cardiopulmonary morbidity and mortality-particularly in patients with cardiovascular disease-that may be prevented with a standard influenza vaccine. However, patients with cardiovascular conditions have a reduced immune response to influenza vaccine, potentially resulting in reduced effectiveness for preventing clinical events. High-dose vaccine augments immune response in cardiac patients, suggesting that a high-dose influenza vaccination strategy may further reduce morbidity and mortality...
May 23, 2018: American Heart Journal
https://www.readbyqxmd.com/read/29909101/lipoprotein-apheresis-acutely-reverses-coronary-microvascular-dysfunction-in-patients-with-severe-hypercholesterolemia
#6
Melinda D Wu, Federico Moccetti, Eran Brown, Brian P Davidson, Tamara Atkinson, J Todd Belcik, George Giraud, P Barton Duell, Sergio Fazio, Hagai Tavori, Sotirios Tsimikas, Jonathan R Lindner
OBJECTIVES: The study evaluated whether lipoprotein apheresis produces immediate changes in resting perfusion in subjects with severe hypercholesterolemia, and whether there is a difference in the response between peripheral and coronary microcirculations. BACKGROUND: Lipoprotein apheresis is used in patients with severe hypercholesterolemia to reduce plasma levels of low-density lipoprotein cholesterol. METHODS: Quantitative contrast-enhanced ultrasound perfusion imaging of the myocardium at rest and skeletal muscle at rest and during calibrated contractile exercise was performed before and immediately after lipoprotein apheresis in 8 subjects with severe hypercholesterolemia, 7 of whom had a diagnosis of familial hypercholesterolemia...
June 9, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29907861/higher-plasma-leptin-levels-are-associated-with-reduced-left-ventricular-mass-and-left-ventricular-diastolic-stiffness-in-black-women-insights-from-the-genetic-epidemiology-network-of-arteriopathy-genoa-study
#7
Daisuke Kamimura, Takeki Suzuki, Wanmei Wang, Matthew deShazo, John E Hall, Michael D Winniford, Iftikhar J Kullo, Thomas H Mosley, Kenneth R Butler, Michael E Hall
Our previous experimental animal data suggest a beneficial effect of leptin on LV structure and function. We hypothesized that leptin levels are associated with lower LV mass and myocardial stiffness which are important risk factors for the development of heart failure with preserved ejection fraction (HFpEF). We evaluated 1172 blacks, in which the prevalence of HFpEF is quite high, with preserved LV ejection fraction (EF > 50%) from the Genetic Epidemiology Network of Arteriopathy Study (mean age 62...
June 15, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29907818/speckle-tracking-stress-echocardiography-in-children-interobserver-and-intraobserver-reproducibility-and-the-impact-of-echocardiographic-image-quality
#8
Lucia Wilke, Francisca E Abellan Schneyder, Markus Roskopf, Andreas C Jenke, Andreas Heusch, Kai O Hensel
Speckle tracking echocardiography (STE) is increasingly used during functional assessments. However, reproducibility and dependence on echocardiographic image quality for speckle tracking stress echocardiography in pediatric patients have not been studied to date. 127 consecutive normotensive children without structural heart disease (mean age 13.4 ± 3.0 years, 50.4% female) underwent a stepwise semisupine cycle ergometric protocol. Left ventricular (LV) myocardial peak strain and strain rate were assessed at rest and during exercise...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29900299/dataset-on-the-use-of-3d-speckle-tracking-echocardiography-in-light-chain-amyloidosis
#9
Antonio Vitarelli, Maria Teresa Petrucci, Silvia Lai, Carlo Gaudio, Lidia Capotosto, Enrico Mangieri, Serafino Ricci, Simone De Sio, Giovanni Truscelli, Federico Vozella, Mario Sergio Pergolini
The dataset presented in this article is related to the research article entitled "Biventricular assessment of light-chain amyloidosis using 3D speckle tracking echocardiography: Differentiation from other forms of myocardial hypertrophy" (Vitarelli et al., 2018) [1], which examined the potential utility of left ventricular (LV) and right ventricular (RV) deformation and rotational parameters derived from three-dimensional speckle-tracking echocardiography (3DSTE) to diagnose cardiac amyloidosis(CA) and differentiate this disease from other forms of myocardial hypertrophy...
June 2018: Data in Brief
https://www.readbyqxmd.com/read/29898740/prognostic-value-of-myocardial-strain-and-late-gadolinium-enhancement-on-cardiovascular-magnetic-resonance-imaging-in-patients-with-idiopathic-dilated-cardiomyopathy-with-moderate-to-severely-reduced-ejection-fraction
#10
Seung-Hoon Pi, Sung Mok Kim, Jin-Oh Choi, Eun Kyoung Kim, Sung-A Chang, Yeon Hyeon Choe, Sang-Chol Lee, Eun-Seok Jeon
BACKGROUND: It has been reported that left ventricular (LV) myocardial strain and late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) imaging have prognostic value in patients with heart failure (HF). However, previous studies included patients with various systolic functions. This study aimed to investigate the prognostic value of LV myocardial strain and LGE on CMR imaging in patients with idiopathic dilated cardiomyopathy (DCM) with reduced ejection fraction (EF < 40%)...
June 14, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29894301/quantification-of-fetal-myocardial-function-in-pregnant-women-with-diabetic-diseases-and-in-normal-controls-using-speckle-tracking-echocardiography-ste
#11
Nina Rolf, Laura Kerschke, Janina Braun, Maria Karina Falkenberg, Kerstin Hammer, Helen Ann Köster, Mareike Möllers, Kathrin Oelmeier de Murcia, Walter Klockenbusch, Ralf Schmitz
PURPOSE: The purpose of our study was to quantify the fetal myocardial function in pregnant women with diabetic diseases (FDM) and in normal controls (FC) using speckle tracking echocardiography (STE). METHODS: In this prospective study, the myocardial strain and dyssynchrony were analyzed using STE in a transversal four-chamber view in 180 fetuses (53 FDM, 127 FC) between 19 and 39 weeks of gestation. The measurements of the global and segmental longitudinal strain of both chambers (2C) and of the single left chamber (1C) were executed offline via QLab 10...
June 12, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29889664/application-of-left-ventricular-strain-in-patients-with-aortic-and-mitral-valve-disease
#12
Arnold C T Ng, Victoria Delgado, Jeroen J Bax
PURPOSE OF REVIEW: Left ventricular (LV) global longitudinal strain (GLS) is widely recognized as a more sensitive measure of LV systolic function compared with LV ejection fraction (LVEF). In addition, the measurement of LVGLS is more reproducible than two-dimensional LVEF. Current guidelines for diagnosis and treatment of valvular heart disease include LVEF as one of the parameters to take into consideration in the clinical decision-making. However, a large body of evidence is showing that LVGLS may be a better prognosticator than LVEF in various valvular heart diseases...
June 9, 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29889135/application-of-left-ventricular-strain-to-patients-with-coronary-artery-disease
#13
Masaaki Takeuchi, Victor Chien-Chia Wu
PURPOSE OF REVIEW: Myocardial strain imaging has gained popularity during the last decade in various clinical scenarios. The objective of this article was to review the potential application of two-dimensional (2D) and three-dimensional (3D) strains in patients with coronary artery disease. RECENT FINDINGS: Reports on the diagnostic accuracy of myocardial deformation analysis using 2D and 3D speckle-tracking analyses to detect significant coronary stenosis at rest or during stress and to evaluate myocardial viability are limited...
June 7, 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29887464/role-of-t2-mapping-in-left-ventricular-reverse-remodeling-after-tavr
#14
M Gastl, P Behm, S Haberkorn, L Holzbach, V Veulemans, C Jacoby, B Schnackenburg, T Zeus, M Kelm, F Bönner
BACKGROUND: Patients with severe aortic stenosis (AS) are subjected to left ventricular hypertrophy (LVH) with increasing morbidity and mortality. Transcatheter aortic valve replacement (TAVR) induces reverse left ventricular remodeling which can be monitored by cardiovascular magnetic resonance (CMR). CMR is able to analyze myocardial tissue properties by magnetic relaxation times (parametric CMR). The objective of this study was to study myocardial T2 relaxation in reverse ventricular remodeling after TAVR...
September 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29885827/prognostic-value-of-myocardial-deformation-imaging-by-cardiac-magnetic-resonance-feature-tracking-in-patients-with-a-first-st-segment-elevation-myocardial-infarction
#15
Gaetano Nucifora, Daniele Muser, Chiara Tioni, Ranjit Shah, Joseph B Selvanayagam
AIM: Scarce data are available whether cardiac magnetic resonance (CMR) assessment of myocardial deformation provides independent and incremental prognostic information in patients with ST-segment elevation myocardial infarction (STEMI). The aim of the present study was to investigate the prognostic utility of CMR feature-tracking derived left ventricular (LV) global circumferential strain (GCS) in STEMI patients. METHODS: A total of 180 patients (mean age 60 ± 12 years, 72% male) admitted because of a first STEMI were included...
May 26, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29882071/left-ventricular-myocardial-deformation-in-takotsubo-syndrome-a-cardiovascular-magnetic-resonance-myocardial-feature-tracking-study
#16
Thomas Stiermaier, Torben Lange, Amedeo Chiribiri, Christian Möller, Tobias Graf, Christina Villnow, Uwe Raaz, Adriana Villa, Johannes T Kowallick, Joachim Lotz, Gerd Hasenfuß, Holger Thiele, Andreas Schuster, Ingo Eitel
OBJECTIVES: This study assessed the applicability and prognostic value of cardiovascular magnetic resonance (CMR) left ventricular deformation analysis in Takotsubo syndrome (TTS). METHODS: CMR-feature tracking was performed blinded in a core laboratory to determine circumferential (CS), radial (RS) and longitudinal strain (LS) in 141 TTS patients participating in this cohort study. A subgroup of consecutive TTS patients (n = 20) was compared with age- and sex-matched controls with anterior ST-segment elevation myocardial infarction (STEMI) and non-STEMI as well as healthy subjects...
June 7, 2018: European Radiology
https://www.readbyqxmd.com/read/29881913/pattern-of-myocardial-99m-tc-hmdp-uptake-and-impact-on-myocardial-function-in-patients-with-transthyretin-cardiac-amyloidosis
#17
Sarah Pradel, Stéphanie Brun, Gérard Victor, Pierre Pascal, Pauline Fournier, David Ribes, Yoan Lavie-Badie, Michel Galinier, Didier Carrié, Isabelle Berry, Olivier Lairez
AIMS: The purpose of the study was to describe the pattern of 99m Tc-labeled phosphate agents myocardial uptake by scintigraphy and explore its impact on left ventricular (LV) functions in transthyretin cardiac amyloidosis (TTR-CA). METHODS: Fifty patients with TTR-CA underwent 99m Tc- hydroxymethylene-diphosphonate (99m Tc-HMDP) scintigraphy and echocardiography with measure of LV thickness, longitudinal strain (LS), systolic and diastolic functions. Cardiac retention by scintigraphy was assessed by visual scoring and the heart/whole body (H/WB) ratio was calculated by dividing counts in the heart by counts in late whole-body images...
June 7, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29879686/evidence-of-extensive-atherosclerosis-coronary-artery-disease-and-myocardial-infarction-in-the-apoe-ins2-akita-mouse-fed-a-western-diet
#18
Daniel E Venegas-Pino, Andrew Lagrotteria, Pei-Wen Wang, Jaiya Morphet, Cassaundra Clapdorp, Yuanyuan Shi, Geoff H Werstuck
BACKGROUND AND AIMS: Diabetic patients with no history of cardiac infarction have a prevalence of coronary atherosclerosis and a risk of heart attack equivalent to euglycemic patients who have coronary atherosclerosis and have suffered a prior myocardial infarction. Although several murine models of diabetes have been established, none of these show indications of cardiac events. In an attempt to establish a diabetic mouse model with coronary atherosclerosis and myocardial injury, we have fed hyperglycemic ApoE-/- :Ins2+/Akita mice a western diet to enhance the dyslipidemic phenotype...
May 23, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29878973/four-ecg-left-ventricular-hypertrophy-criteria-and-the-risk-of-cardiovascular-events-and-mortality-in-patients-with-vascular-disease
#19
Monique E A M van Kleef, Frank L J Visseren, Joris W P Vernooij, Hendrik M Nathoe, Maarten-Jan M Cramer, Remy H H Bemelmans, Yolanda van der Graaf, Wilko Spiering
OBJECTIVE: The relation between different electrocardiographic left ventricular hypertrophy (ECG-LVH) criteria and cardiovascular risk in patients with clinical manifest arterial disease is unclear. Therefore, we determined the association between four ECG-LVH criteria: Sokolow-Lyon, Cornell product, Cornell/strain index and Framingham criterion; and risk of cardiovascular events and mortality in this population. METHODS: Risk of cardiovascular events was estimated in 6913 adult patients with clinical manifest arterial disease originating from the Secondary Manifestations of ARTerial disease (SMART) cohort...
June 6, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29877299/ascending-aorta-and-myocardial-mechanics-in-patients-with-clinically-normal-bicuspid-aortic-valve
#20
Gaetano Nucifora, Jamie Miller, Carl Gillebert, Ranjit Shah, Rebecca Perry, Cherie Raven, Majo X Joseph, Joseph B Selvanayagam
Aortic valve dysfunction and aortic wall changes are well-known complications of bicuspid aortic valve (BAV) disease. The aim of the present study was to investigate whether a remodeling process of the left ventricle (LV) is present in patients with isolated BAV. Twenty-two consecutive patients (39 ± 15 years, 9 males) with clinically normal BAV and 18 age- and gender-matched control subjects (37 ± 10 years, 9 males) were included. Cardiovascular magnetic resonance (CMR) imaging was performed to evaluate LV function, aortic valve morphology, aortic orifice area, and ascending aorta (AA) dimensions...
June 6, 2018: International Heart Journal
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