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Myocardial strain

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https://www.readbyqxmd.com/read/29685078/prelabour-myocardial-deformation-and-cardiac-output-in-fetuses-that-develop-intrapartum-compromise-at-term-a-prospective-observational-study
#1
Amal A Alsolai, Larissa N Bligh, Ristan M Greer, Alexander Gooi, Sailesh Kumar
OBJECTIVE: Redistribution of cardiac output is responsible for the "brain sparing" effect seen during periods of acute or chronic fetal stress. We investigated the relationship between prelabour cardiac function in fetuses that subsequently developed intrapartum fetal compromise (IFC). METHODS: A blinded, prospective, observational, cohort study, at Mater Mother's Hospital, Brisbane, Australia. A cohort of 284 women with uncomplicated singleton pregnancies underwent ultrasound every 2 weeks from 36 weeks until delivery...
April 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29683198/two-dimensional-speckle-tracking-echocardiographic-evaluation-of-the-longitudinal-deformation-of-the-left-ventricular-myocardium-in-patients-with-severe-coronary-artery-tortuosity
#2
Mohsen Khosravani-Rudpishi, Niloofar Akhavan-Khaleghi, Ali Hosseinsabet
PURPOSE: Coronary artery tortuosity (CAT) is an anatomical condition in which epicardial coronary arteries have abnormal curves or spiral courses. Although correlated with higher rates of positive stress test, its effects on the myocardial function remain to be clearly defined. METHODS: We included in this cross-sectional study and evaluated with 2D speckle-tracking echocardiography 40 consecutive patients admitted to our hospital for selective coronary angiography which showed severe CAT without significant epicardial coronary artery stenosis, and 40 consecutive subjects matched for age, hypertension, and diabetes in whom selective coronary angiography showed neither CAT nor significant epicardial coronary artery stenosis...
April 23, 2018: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/29681423/ultrasonic-cavitation-enabled-treatment-for-therapy-of-hypertrophic-cardiomyopathy-proof-of-principle
#3
Douglas L Miller, Xiaofang Lu, Chunyan Dou, Yiying I Zhu, Rachael Fuller, Kristina Fields, Mario L Fabiilli, Gabe E Owens, David Gordon, Oliver D Kripfgans
Ultrasound myocardial cavitation-enabled treatment was applied to the SS-16BN rat model of hypertrophic cardiomyopathy for proof of the principle underlying myocardial reduction therapy. A focused ultrasound transducer was targeted using 10-MHz imaging (10 S, GE Vivid 7) to the left ventricular wall of anesthetized rats in a warmed water bath. Pulse bursts of 4-MPa peak rarefactional pressure amplitude were intermittently triggered 1:8 heartbeats during a 10-min infusion of a microbubble suspension. Methylprednisolone was given to reduce initial inflammation, and Losartan was given to reduce fibrosis in the healing tissue...
April 19, 2018: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29681243/association-between-myocardial-extracellular-volume-and-strain-analysis-through-cardiovascular-magnetic-resonance-with-histological-myocardial-fibrosis-in-patients-awaiting-heart-transplantation
#4
Yue Cui, Yukun Cao, Jing Song, Nianguo Dong, Xiangchuang Kong, Jing Wang, Yating Yuan, Xiaolei Zhu, Xu Yan, Andreas Greiser, Heshui Shi, Ping Han
BACKGROUND: Cardiovascular magnetic resonance (CMR)-derived extracellular volume (ECV) and tissue tracking strain analyses are proposed as non-invasive methods for quantifying myocardial fibrosis and deformation. This study sought (1) to histologically validate myocardial ECV against the collagen volume fraction (CVF) measured from tissue samples of patients undergoing heart transplantation and (2) to detect the correlations between myocardial systolic strain and the myocardial ECV and histological CVF in patients undergoing heart transplantation...
April 23, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29680337/t1-mapping-by-cardiac-magnetic-resonance-and-multidimensional-speckle-tracking-strain-by-echocardiography-for-the-detection-of-acute-cellular-rejection-in-cardiac-allograft-recipients
#5
Leyla Elif Sade, Tuncay Hazirolan, Hatice Kozan, Handan Ozdemir, Mutlu Hayran, Serpil Eroglu, Bahar Pirat, Atilla Sezgin, Haldun Muderrisoglu
OBJECTIVES: The aim of this study was to test the hypothesis that echocardiographic strain imaging, by tracking subtle alterations in myocardial function, and cardiac magnetic resonance T1 mapping, by quantifying tissue properties, are useful and complement each other to detect acute cellular rejection in heart transplant recipients. BACKGROUND: Noninvasive alternatives to endomyocardial biopsy are highly desirable to monitor acute cellular rejection. METHODS: Surveillance endomyocardial biopsies, catheterizations, and echocardiograms performed serially according to institutional protocol since transplantation were retrospectively reviewed...
April 14, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29680336/cardiac-structural-and-functional-consequences-of-amyloid-deposition-by-cardiac-magnetic-resonance-and-echocardiography-and-their-prognostic-roles
#6
Daniel S Knight, Giulia Zumbo, William Barcella, Jennifer A Steeden, Vivek Muthurangu, Ana Martinez-Naharro, Thomas A Treibel, Amna Abdel-Gadir, Heerajnarain Bulluck, Tushar Kotecha, Rohin Francis, Tamer Rezk, Candida C Quarta, Carol J Whelan, Helen J Lachmann, Ashutosh D Wechalekar, Julian D Gillmore, James C Moon, Philip N Hawkins, Marianna Fontana
OBJECTIVES: This cross-sectional study aimed to describe the functional and structural cardiac abnormalities that occur across a spectrum of cardiac amyloidosis burden and to identify the strongest cardiac functional and structural prognostic predictors in amyloidosis using cardiac magnetic resonance (CMR) and echocardiography. BACKGROUND: Cardiac involvement in light chain and transthyretin amyloidosis is the main driver of prognosis and influences treatment strategies...
April 13, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29678512/galectin-3-is-associated-with-left-ventricular-reverse-remodeling-and-outcome-after-percutaneous-mitral-valve-repair
#7
Christine S Zuern, Niklas Floss, Iris I Mueller, Christian Eick, Martin Duckheim, Johannes Patzelt, Meinrad Gawaz, Andreas E May, Karin A L Mueller
BACKGROUND: Plasma Galectin-3 is a marker of myocardial inflammation and fibrosis, was associated with left ventricular (LV) reverse remodeling after conventional surgical mitral valve repair (MVR) and predicted clinical events in patients undergoing transcatheter aortic valve replacement (TAVR). We aimed to evaluate the association between pre-interventional Galectin-3 levels and (1) reverse LV remodeling and (2) major adverse cardiovascular events (MACE) in patients undergoing percutaneous MVR...
April 7, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29676955/mitochondrial-genome-modulates-myocardial-akt-glut-hk-salvage-pathway-in-spontaneously-hypertensive-rats-adapted-to-chronic-hypoxia
#8
Iveta Nedvedova, David Kolar, Barbara Elsnicova, Daniela Hornikova, Jiri Novotny, Martin Kalous, Michal Pravenec, Jan Neckar, Frantisek Kolar, Jitka M Zurmanova
Recently we have shown that adaptation to continuous normobaric hypoxia (CNH) decreases myocardial ischemia/reperfusion injury in spontaneously hypertensive rats (SHR) and in conplastic strain (SHR-mtBN ). The protective effect was stronger in the latter group characterized by a selective replacement of SHR mitochondrial genome with that of a more ischemia-resistant Brown Norway strain. The aim of the present study was to examine the possible involvement of the hypoxia inducible factor (HIF)-dependent pathway of the protein kinase B/glucose transporters/hexokinase (Akt/GLUT/HK) in this mitochondrial genome-related difference of the cardioprotective phenotype...
April 20, 2018: Physiological Genomics
https://www.readbyqxmd.com/read/29675621/myocardial-function-in-primary-antiphospholipid-syndrome-using-speckle-tracking-echocardiography
#9
Gabriela Medina, Eduardo Gómez-Bañuelos, Erick Calderón-Aranda, María Pilar Cruz-Domínguez, Olga Vera-Lastra, Luis J Jara
Antiphospholipid syndrome (APS) patients have high cardiovascular risk. Speckle-tracking echocardiography (STE) detects myocardial function. To evaluate the myocardial function in primary APS (PAPS) patients using two-dimensional echocardiography (2-D) obtaining values of left ventricle global longitudinal strain (GLS) by STE. Patients with PAPS, > 16 years, both genders, without signs and symptoms of heart disease were recruited and matched with healthy controls by age and gender. Demographic, clinical data, and cardiovascular risk factors were recorded...
April 19, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29673853/biventricular-dyssynchrony-on-cardiac-magnetic-resonance-imaging-and-its-correlation-with-myocardial-deformation-ventricular-function-and-objective-exercise-capacity-in-patients-with-repaired-tetralogy-of-fallot
#10
Pantelis Kalaitzidis, Stefan Orwat, Aleksander Kempny, Radke Robert, Brigitte Peters, Samir Sarikouch, Philipp Beerbaum, Helmut Baumgartner, Gerhard-Paul Diller
BACKGROUND: Electrical dyssynchrony and prolonged QRS duration are common in patients with repaired tetralogy of Fallot (ToF). It has been linked to increased risk of sudden cardiac death and right ventricular (RV) dysfunction. We investigated myocardial dyssynchrony using cardiac magnetic resonance imaging (CMR) and feature tracking analysis (FT) in this setting and compared it to myocardial deformation, conventional parameters of ventricular dysfunction and clinical parameters. METHODS AND RESULTS: Patients underwent standardized CMR investigations as part of a nationwide study...
April 12, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29669563/a-comparison-of-both-dense-and-feature-tracking-techniques-with-tagging-for-the-cardiovascular-magnetic-resonance-assessment-of-myocardial-strain
#11
J Jane Cao, Nora Ngai, Lynette Duncanson, Joshua Cheng, Kathleen Gliganic, Qizhi Chen
BACKGROUND: Myocardial strain is increasingly recognized as an important assessment for myocardial function. In addition, it also improves outcome prediction. However, there is lack of standardization in strain evaluation by cardiovascular magnetic resonance (CMR). In this study we compared strain values using multiple techniques and multiple vendor products. METHODS: Prospectively recruited patients with cardiomyopathy of diverse etiology (N = 77) and healthy controls (N = 10) underwent CMR on a 1...
April 19, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29667079/fetal-regional-myocardial-strain-rate-in-the-membranous-ventricular-septum-changes-with-gestational-age-and-the-left-ventricular-mass-and-predictive-value-for-a-complete-membranous-ventricular-septum-without-defect
#12
Li-Juan Zhang, Ke-Qi Chen, Yun-Yan Shi, Xiao-Zhi Zheng
To describe the fetal regional myocardial strain rate in the membranous ventricular septum across gestation and to determine their predictive value for a complete membranous ventricular septum (without defect) after delivery. In 1150 fetuses, the peak systolic strain rate (SRs), peak early diastolic strain rate (SRe) and peak late diastolic strain rate (SRa) in the membranous ventricular septum were measured at four time points across gestation (18-20, 24-26, 30-32 and 36-38 weeks). The integrity of the interventricular septum was examined at 12 weeks' postnatal age...
April 17, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29664336/left-ventricular-myocardial-deformation-on-cine-mr-images-relationship-to-severity-of-disease-and-prognosis-in-amyloid-light-chain-amyloidosis
#13
Ke Wan, Jiayu Sun, Dan Yang, Hong Liu, Jie Wang, Wei Cheng, Qing Zhang, Zhi Zeng, Tianjing Zhang, Andreas Greiser, Marie-Pierre Jolly, Yuchi Han, Yucheng Chen
Purpose To measure left ventricular (LV) myocardial strain with cine magnetic resonance (MR) imaging and a deformable registration algorithm (DRA) and to assess the prognostic value of myocardial strain in patients with light-chain (AL) amyloidosis. Materials and Methods In this prospective study, 78 consecutive patients with AL amyloidosis who underwent contrast material-enhanced cardiac MR imaging were enrolled at West China Hospital. LV myocardial strains and late gadolinium enhancement (LGE) were evaluated...
April 17, 2018: Radiology
https://www.readbyqxmd.com/read/29659790/ratio-of-transmitral-early-filling-velocity-to-early-diastolic-strain-rate-predicts-long-term-risk-of-cardiovascular-morbidity-and-mortality-in-the-general-population
#14
Mats Christian Højbjerg Lassen, Sofie Reumert Biering-Sørensen, Flemming Javier Olsen, Kristoffer Grundtvig Skaarup, Kirsten Tolstrup, Atif Nazier Qasim, Rasmus Møgelvang, Jan Skov Jensen, Tor Biering-Sørensen
Aims: It has previously been demonstrated that the ratio of early mitral inflow velocity to global diastolic strain rate (E/e'sr) is a significant predictor of cardiac events in specific patient populations. The utility of this measurement to predict cardiovascular events in a general population has not been evaluated. Methods and results: A total of 1238 participants in a general population study underwent a health examination including echocardiography where global longitudinal strain (GLS) and E/e'sr were determined...
April 5, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29657869/impaired-cardiac-and-vascular-motion-in-patients-with-takayasu-s-arteritis-a-velocity-vector-imaging-based-study
#15
Selen Yurdakul, Fatma Alibaz-Öner, Haner Direskeneli, Saide Aytekin
Objective: Takayasu's arteritis (TAK) is a chronic inflammatory vasculitis of the aorta and its major branches. In the present study, we aimed to evaluate the motion of the vascular wall and myocardial contractility by using a novel strain imaging method, velocity vector imaging (VVI), in patients with TAK. We also aimed to compare them with another inflammatory autoimmune disorder, systemic lupus erythematosus (SLE). Methods: We studied 33 patients with TAK, 18 patients with SLE, and 20 age- and sex-matched controls...
March 2018: European Journal of Rheumatology
https://www.readbyqxmd.com/read/29657045/the-relationship-between-left-ventricular-structure-and-function-in-the-elite-rugby-football-league-athlete-as-determined-by-conventional-echocardiography-and-myocardial-strain-imaging
#16
Lynsey Forsythe, David Hunter MacIver, Christopher Johnson, Keith George, John Somauroo, Michael Papadakis, Benjamin Brown, Mohammad Qasem, David Oxborough
AIMS: The aims of this study were to establish the left ventricular (LV) phenotype in rugby football league (RFL) athletes and to mathematically model the association between LV size, strain (ɛ) and ejection fraction (EF). METHODS AND RESULTS: 139 male athletes underwent echocardiographic LV evaluation including ɛ imaging. Non-athletic males were used for comparison. All absolute and scaled structural indices were significantly larger (P < 0.05) in athletes with a predominance for normal LV geometry...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29649657/contribution-of-computational-model-for-assessment-of-heart-tissue-local-stress-caused-by-suture-in-lvad-implantation
#17
A Chalon, J Favre, B Piotrowski, V Landmann, D Grandmougin, J-P Maureira, P Laheurte, N Tran
STUDY: Implantation of a Left Ventricular Assist Device (LVAD) may produce both excessive local tissue stress and resulting strain-induced tissue rupture that are potential iatrogenic factors influencing the success of the surgical attachment of the LVAD into the myocardium. By using a computational simulation compared to mechanical tests, we sought to investigate the characteristics of stress-induced suture material on porcine myocardium. METHODS: Tensile strength experiments (n = 8) were performed on bulk left myocardium to establish a hyperelastic reduced polynomial constitutive law...
March 28, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29648692/multimodality-imaging-for-evaluation-of-chest-pain-using-strain-analysis-at-rest-and-peak-exercise
#18
Mohamad Jihad Mansour, Wael AlJaroudi, Omar Hamoui, Sarah Chaaban, Elie Chammas
BACKGROUND: Exercise stress echocardiography (SE) is commonly used for diagnosing coronary artery disease (CAD). The use of quantitative echocardiographic measures such as strain imaging is expected to improve the sensitivity of conventional SE which relies on the visual diagnosis of wall-motion abnormalities (WMAs). This study is set to demonstrate the added value of resting and exercise strain analysis to detect underlying microangiopathy and inducible myocardial ischemia during a resting and SE in comparison with the results of coronary computed tomographic angiogram (CCTA)...
April 12, 2018: Echocardiography
https://www.readbyqxmd.com/read/29643812/left-ventricular-wall-stress-is-sensitive-marker-of-hypertrophic-cardiomyopathy-with-preserved-ejection-fraction
#19
Xiaodan Zhao, Ru-San Tan, Hak-Chiaw Tang, Soo-Kng Teo, Yi Su, Min Wan, Shuang Leng, Jun-Mei Zhang, John Allen, Ghassan S Kassab, Liang Zhong
Hypertrophic cardiomyopathy (HCM) patients present altered myocardial mechanics due to the hypertrophied ventricular wall and are typically diagnosed by the increase in myocardium wall thickness. This study aimed to quantify regional left ventricular (LV) shape, wall stress and deformation from cardiac magnetic resonance (MR) images in HCM patients and controls, in order to establish superior measures to differentiate HCM from controls. A total of 19 HCM patients and 19 controls underwent cardiac MR scans. The acquired MR images were used to reconstruct 3D LV geometrical models and compute the regional parameters (i...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29627138/longitudinal-changes-in-right-ventricular-function-in-tetralogy-of-fallot-in-the-initial-years-after-surgical-repair
#20
Michael P DiLorenzo, Okan U Elci, Yan Wang, Anirban Banerjee, Tomoyuki Sato, Bonnie Ky, Elizabeth Goldmuntz, Laura Mercer-Rosa
BACKGROUND: Right ventricular (RV) dysfunction is associated with adverse long-term outcomes in patients with tetralogy of Fallot. Little is known about RV function in the first years after surgical repair. The aim of this study was to investigate perioperative changes in myocardial deformation using global longitudinal strain. METHODS: A retrospective analysis of patients with surgically repaired tetralogy of Fallot was performed. Global longitudinal peak systolic RV strain was measured on early postoperative echocardiograms, two subsequent postoperative echocardiograms through 2 years postoperatively, and preoperative echocardiograms, when available...
April 4, 2018: Journal of the American Society of Echocardiography
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