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Sverre U Johnson, Asle Hoffart
We aimed to systematically evaluate a generic model of metacognitive therapy (MCT) with a highly comorbid anxiety disorder patient, that had been treated with diagnosis-specific cognitive-behavioral therapy (CBT) without significant effect. Traditionally, CBT has progressed within a disorder-specific approach, however, it has been suggested that this could be less optimal with highly comorbid patients. To address comorbidity, transdiagnostic treatment models have been emerging. This case study used an AB-design with repeated assessments during each therapy session and a 1-year follow-up assessment to evaluate the effectiveness of MCT...
2016: Frontiers in Psychology
Conxa Perpiñá, Mara Segura, Sergio Sánchez-Reales
OBJECTIVE: The aim of the present study was to compare decision-making and cognitive flexibility in patients with disordered eating and weight, ranging from anorexia nervosa to obesity, and a healthy group. METHOD: Participants were 113 patients (86 with eating disorders and 27 with obesity), and a group of 39 healthy subjects; all completed the Iowa gambling task, the Wisconsin Card Sorting Test and several clinical self-report measures. RESULTS: Eating disordered and obese patients showed impaired performance on the decision-making task, and the obese group showed the worst performance on the set-shifting task...
October 15, 2016: Eating and Weight Disorders: EWD
Aimee Zisner, Theodore P Beauchaine
Trait impulsivity, which is often defined as a strong preference for immediate over delayed rewards and results in behaviors that are socially inappropriate, maladaptive, and short-sighted, is a predisposing vulnerability to all externalizing spectrum disorders. In contrast, anhedonia is characterized by chronically low motivation and reduced capacity to experience pleasure, and is common to depressive disorders. Although externalizing and depressive disorders have virtually nonoverlapping diagnostic criteria in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, heterotypic comorbidity between them is common...
November 2016: Development and Psychopathology
Allison N Macdonald, Katrina B Goines, Derek M Novacek, Elaine F Walker
Accumulating behavioral and genetic research suggests that most forms of psychopathology share common genetic and neural vulnerabilities and are manifestations of a relatively few core underlying processes. These findings support the view that comorbidity mostly arises, not from true co-occurrence of distinct disorders, but from the behavioral expression of shared vulnerability processes across the life span. The purpose of this review is to examine the role of the prefrontal cortex (PFC) in the shared vulnerability mechanisms underlying the clinical phenomena of comorbidity from a transdiagnostic and ontogenic perspective...
November 2016: Development and Psychopathology
Amelia Aldao, Dylan G Gee, Andres De Los Reyes, Ilana Seager
In response to rapidly growing rates of comorbidity among psychiatric disorders, clinical scientists have become interested in identifying transdiagnostic processes that can help explain dysfunction across diagnostic categories (e.g., Kring & Sloan, 2009). One factor that has received a great deal of attention is that of emotion regulation, namely, the ability to modulate the intensity and/or duration of emotional states (e.g., Cicchetti, Ackerman, & Izard, 1995; Gross, 1998). Recent theoretical and empirical work has begun to emphasize the role that emotion regulation plays in the temporal comorbidity between internalizing and externalizing conditions (e...
November 2016: Development and Psychopathology
Ellen M Kessel, Alexandria Meyer, Greg Hajcak, Lea R Dougherty, Dana C Torpey-Newman, Gabrielle A Carlson, Daniel N Klein
There is increasing interest among developmental psychopathologists in broad transdiagnostic factors that give rise to a wide array of clinical presentations (multifinality), but little is known about how these processes lead to particular psychopathological manifestations over the course of development. We examined whether individual differences in the error-related negativity (ΔERN), a neural indicator of error monitoring, predicts whether early persistent irritability, a prototypical transdiagnostic construct, is associated with later internalizing versus externalizing outcomes...
November 2016: Development and Psychopathology
Johanna Özlem Schäfer, Eva Naumann, Emily Alexandra Holmes, Brunna Tuschen-Caffier, Andrea Christiane Samson
The role of emotion regulation in subclinical symptoms of mental disorders in adolescence is not yet well understood. This meta-analytic review examines the relationship between the habitual use of prominent adaptive emotion regulation strategies (cognitive reappraisal, problem solving, and acceptance) and maladaptive emotion regulation strategies (avoidance, suppression, and rumination) with depressive and anxiety symptoms in adolescence. Analyzing 68 effect sizes from 35 studies, we calculated overall outcomes across depressive and anxiety symptoms as well as psychopathology-specific outcomes...
October 12, 2016: Journal of Youth and Adolescence
Kasey Stanton, David C Rozek, Sara M Stasik-O'Brien, Stephanie Ellickson-Larew, David Watson
Although personality and emotion regulation abilities appear to overlap considerably, few studies have adopted an integrative approach by examining personality and emotion regulation together. Therefore, it is unclear how much incremental power emotion regulation demonstrates in predicting psychopathology beyond personality traits, and vice versa. Results from a community sample characterized by high levels of psychopathology (N = 299) indicated that personality and emotion regulation represent strongly related but distinguishable constructs, with both showing incremental power beyond the other in many cases in predicting self-reported and interview-rated psychopathology...
October 2016: Journal of Abnormal Psychology
Christine A Rabinak, Shoko Mori, Maryssa Lyons, Mohammed R Milad, K Luan Phan
BACKGROUND: Fear-based disorders, like social anxiety disorder (SAD) and posttraumatic stress disorder (PTSD), are characterized by an exaggerated fear response and avoidance to trigger cues, suggesting a transdiagnostic mechanism of psychopathology. Current theories suggest that abnormalities in conditioned fear is a primary contributor to the pathophysiology of these disorders. The primary goal of this study was to compare acquisition of conditioned stimulus (CS) and aversive unconditioned stimulus (US) contingencies during fear learning and extinction in individuals with SAD and PTSD...
September 23, 2016: Journal of Affective Disorders
Milena Gandy, Eyal Karin, Vincent J Fogliati, Sarah McDonald, Nick Titov, Blake F Dear
OBJECTIVE: Anxiety and depression are highly prevalent in people with epilepsy (PWE) and contribute to increased disability. Unfortunately, there are numerous barriers (e.g., cost, distance, and stigma) and service gaps (e.g., lack of services and trained clinicians) that prevent many PWE from accessing traditional face-to-face psychological services. The aim of the present study was to examine the feasibility of a new transdiagnostic Internet-delivered cognitive behavioral therapy (iCBT) program, the Chronic Conditions Course, to simultaneously treat symptoms of anxiety, depression, and disability...
October 7, 2016: Epilepsia
Costina Ruxandra Păsărelu, Gerhard Andersson, Lise Bergman Nordgren, Anca Dobrean
Anxiety and depressive disorders are often comorbid. Transdiagnostic and tailored treatments seem to be promising approaches in dealing with comorbidity. Although several primary studies have examined the effects of Internet-delivered cognitive behavior therapy (iCBT) for anxiety and depression, no meta-analysis including different types of iCBT that address comorbidity has been conducted so far. We conducted systematic searches in databases up to 1 July 2016. Only randomized trials comparing transdiagnostic/tailored iCBT for adult anxiety and/or depression with control groups were included...
October 7, 2016: Cognitive Behaviour Therapy
Eric Stice, Jeff M Gau, Paul Rohde, Heather Shaw
Because no single report has examined risk factors that predict future onset each type of eating disorder and core symptom dimensions that crosscut disorders, we addressed these aims to advance knowledge regarding risk factor specificity. Data from 3 prevention trials that targeted young women with body dissatisfaction (N = 1,272; Mage = 18.5, SD = 4.2) and collected annual diagnostic interview data over 3-year follow-up were combined to identify predictors of subthreshold/threshold anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and purging disorder (PD)...
October 6, 2016: Journal of Abnormal Psychology
James F Boswell, Matteo Bugatti
Recent work has highlighted that process-outcome relationships are likely to vary depending on the client, yet there is little direct evidence regarding specific intervention effects in individual clients. This study attempted to address the hypothesis that some clients reveal more than others regarding the impact of specific interventions. Intensive case study analyses were applied to 2 clients with principal major depressive disorder and comorbid anxiety disorders receiving transdiagnostic psychotherapy. Clients completed a battery of symptom and psychological assessments of mindfulness, cognitive reappraisal use, and emotion avoidance on many occasions throughout treatment...
October 6, 2016: Journal of Counseling Psychology
Alexander M Talkovsky, Kelly L Green, Adriana Osegueda, Peter J Norton
Anxiety and depression co-occur at high rates, and their comorbidity typically creates a more severe clinical presentation then either alone. The effect of comorbid depression appears to vary across anxiety and related disorders. Transdiagnostic treatments present a promising option to improve comorbid conditions by targeting shared factors (e.g., information processing biases). The purpose of this study was to examine the reciprocal effects of secondary depression in transdiagnostic group cognitive behavioral therapy for anxiety (TGCBT)...
September 28, 2016: Journal of Anxiety Disorders
Agustín Ibáñez, Adolfo M García, Sol Esteves, Adrián Yoris, Edinson Muñoz, Lucila Reynaldo, Marcos Luis Pietto, Federico Adolfi, Facundo Manes
Multiple disorders once jointly conceived as 'nervous diseases' became segregated by the distinct institutional traditions forged in neurology and psychiatry. As a result, each field specialized in the study and treatment of a subset of such conditions. Here we propose new avenues for interdisciplinary interaction through a triangulation of both fields with social neuroscience. To this end, we review evidence from five relevant domains (facial emotion recognition, empathy, theory of mind, moral cognition, social context assessment), highlighting their common disturbances across neurological and psychiatric conditions and discussing their multiple pathophysiological mechanisms...
October 6, 2016: Social Neuroscience
Nina Reinholt, Ruth Aharoni, Clas Winding, Nicole Rosenberg, Bent Rosenbaum, Sidse Arnfred
Comorbidity among the anxiety disorders is common and may negatively impact treatment outcome. Potentially, transdiagnostic cognitive-behavioral treatments (CBT) deal more effectively with comorbidity than standard CBT. The present study tested the effectiveness of The Unified Protocol (UP) applied to Mental Health Services. Pre-post-treatment effects were examined for psychiatric outpatients with anxiety disorders receiving UP treatment in groups. Forty-seven patients (mean-age = 34.1 (SD = 9.92), 77% females) with a principal diagnosis of anxiety were included...
October 5, 2016: Cognitive Behaviour Therapy
Nickolai Titov, Vincent J Fogliati, Lauren G Staples, Milena Gandy, Luke Johnston, Bethany Wootton, Olav Nielssen, Blake F Dear
BACKGROUND: Symptoms of anxiety and depression are prevalent in older adults. AIMS: To compare clinician-guided and self-guided versions of a transdiagnostic internet-delivered cognitive-behavioural therapy (iCBT) intervention for adults aged 60 years and above. METHOD: Adults (n=433) with symptoms of anxiety and depression were randomly allocated to: (1) clinician-guided treatment (n=153); (2) initial clinician interview followed by self-guided treatment (n=140); or (3) self-guided treatment without interview (n=140)...
January 2016: BJPsych Open
Judy Garber, Steven M Brunwasser, Argero A Zerr, Karen T G Schwartz, Karen Sova, V Robin Weersing
Anxiety and depression are highly comorbid and share several common etiological processes. Therefore, it may be more efficient to develop interventions that treat or prevent these problems together rather than as separate entities. The present meta-analytic review examined whether interventions for children and adolescents that explicitly targeted either anxiety or depression showed treatment specificity or also impacted the other outcome (i.e. cross-over effects). We addressed this question both within the same type of study (i...
October 2016: Depression and Anxiety
Charlotte Heleniak, Jessica L Jenness, Ann Vander Stoep, Elizabeth McCauley, Katie A McLaughlin
Child maltreatment is a robust risk factor for internalizing and externalizing psychopathology in children and adolescents. We examined the role of disruptions in emotion regulation processes as a developmental mechanism linking child maltreatment to the onset of multiple forms of psychopathology in adolescents. Specifically, we examined whether child maltreatment was associated with emotional reactivity and maladaptive cognitive and behavioral responses to distress, including rumination and impulsive behaviors, in two separate samples...
June 2016: Cognitive Therapy and Research
Jessica McClelland, Bethan Dalton, Maria Kekic, Savani Bartholdy, Iain C Campbell, Ulrike Schmidt
OBJECTIVE: Eating Disorders (ED) and obesity are suggested to involve a spectrum of self-regulatory control difficulties. Temporal discounting (TD) tasks have been used to explore this idea. This systematic review examines behavioural and neuroimaging TD data in ED and obesity. METHOD: Using PRISMA guidelines, we reviewed relevant articles in MEDLINE, PsycINFO and Embase from inception until 17th August 2016. Studies that reported behavioural differences in TD and/or TD neuroimaging data in ED/obesity were included...
September 28, 2016: Neuroscience and Biobehavioral Reviews
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