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Calprotectin

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https://www.readbyqxmd.com/read/28207476/faecal-calprotectin-in-cystic-fibrosis-and-it-s-relation-to-disease-parameters-a-longitudinal-analysis-over-12-years
#1
Helmut Ellemunter, Alexander Engelhardt, Katharina Schüller, Gratiana Steinkamp
OBJECTIVES: Faecal calprotectin (FC) is a marker of inflammation in the intestinal tract. We assessed FC levels longitudinally in patients with cystic fibrosis (CF) and evaluated the relation between FC results and relevant markers of disease. METHODS: Calprotectin was measured in faecal samples starting in 2003 and values were stored in the centre's patient database. In this retrospective analysis we searched for associations of FC concentrations with disease severity and progression...
February 15, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28204866/vedolizumab-treatment-for-immune-checkpoint-inhibitor-induced-enterocolitis
#2
Viktoria Bergqvist, Erik Hertervig, Peter Gedeon, Marija Kopljar, Håkan Griph, Sara Kinhult, Ana Carneiro, Jan Marsal
Immune checkpoint inhibitors (ICPI), such as ipilimumab [anti-cytotoxic T-lymphocyte antigen-4 (CTLA-4) antibody] and nivolumab or pembrolizumab [anti-programmed cell death protein-1 (PD-1) antibodies], improve survival in several cancer types. Since inhibition of CTLA-4 or PD-1 leads to non-selective activation of the immune system, immune-related adverse events (irAEs) are frequent. Enterocolitis is a common irAE, currently managed with corticosteroids and, if necessary, anti-tumor necrosis factor-α therapy...
February 15, 2017: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/28203278/efficacy-of-granulocyte-and-monocyte-apheresis-for-antibiotic-refractory-pouchitis-after-proctocolectomy-for-ulcerative-colitis-an-open-label-prospective-multicentre-study
#3
Takayuki Yamamoto, Toshiaki Tanaka, Tadashi Yokoyama, Takahiro Shimoyama, Hiroki Ikeuchi, Motoi Uchino, Toshiaki Watanabe
BACKGROUND: Granulocyte and monocyte apheresis (GMA) has shown therapeutic efficacy in active ulcerative colitis (UC). We thought that in patients with pouchitis after proctocolectomy for UC, GMA might produce immunological effects in the intestinal mucosa, and improve clinical symptoms. This prospective study was to evaluate the efficacy of GMA for antibiotic-refractory pouchitis after proctocolectomy for UC. METHODS: A total of 13 patients with pouchitis disease activity index (PDAI) > 7 unresponsive to 2 weeks of antibiotic therapy were included...
February 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28196533/assessment-of-complementary-feeding-of-canadian-infants-effects-on-microbiome-oxidative-stress-a-randomized-controlled-trial
#4
Wafaa Qasem, Meghan B Azad, Zakir Hossain, Elnaz Azad, Sarah Jorgensen, Sandra Castillo San Juan, Chenxi Cai, Ehsan Khafipour, Trust Beta, L Jackson Roberts, James Friel
BACKGROUND: The World Health Organization recommends exclusive breastfeeding until 6 months followed by introduction of iron-rich complementary foods (CFs). The aim of this study was to determine the impact of different iron-rich CFs on infant gut inflammation and microbiota. METHODS: Eighty-seven exclusively breastfed infants were randomly assigned to receive one of the following as their first CF: iron-fortified cereal (Cer), iron-fortified cereal with fruit (Cer + Fr), or meat (M)...
February 14, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28195066/successful-therapy-of-clostridium-difficile-infection-with-fecal-microbiota-transplantation
#5
P C Konturek, J Koziel, W Dieterich, D Haziri, S Wirtz, I Glowczyk, K Konturek, M F Neurath, Y Zopf
Clostridium difficile infection (CDI) is the most common cause of infectious diarrhea and represents an important burden for healthcare worldwide. Symptoms of severe CDI include watery, foul-smelling diarrhea, peripheral leucocytosis, increased C-reactive protein (CRP), acute renal failure, hypotension and pseudomembranous colitis. Recent studies indicate that the main cause of CDI is dysbiosis, an imbalance in the normal gut microbiota. The restoration of a healthy gut microbiota composition via fecal microbiota transplantation (FMT) recently became more popular...
December 2016: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://www.readbyqxmd.com/read/28193167/helicobacter-pylori-prevalence-and-clinical-significance-in-patients-with-quiescent-crohn-s-disease
#6
Adi Lahat, Uri Kopylov, Sandra Neuman, Nina Levhar, Doron Yablecovitch, Benjamin Avidan, Batia Weiss, Shomron Ben-Horin, Rami Eliakim
BACKGROUND: Helicobacter pylori (HP) infection is present in about 50% of the global population, and is associated with chronic gastritis, peptic disease and gastric malignancies. HP prevalence in Crohn's disease (CD) patients was shown to be low compared to the general population, and its influence on disease activity is yet to be determined. Our aims were to determine the prevalence of HP in a selected group of CD patients with quiescent disease, and to assess the influence of its eradication on disease activity and endoscopic and laboratory activity measures...
February 13, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28188944/comparison-of-fecal-calprotectin-in-exclusively-breastfed-and-formula-or-mixed-fed-infants-in-the-first-six-months-of-life
#7
Masoumeh Asgarshirazi, Mamak Shariat, Fatemeh Nayeri, Hosein Dalili, Alireza Abdollahi
We conducted this study to compare fecal calprotectin between exclusively breastfed and formula or mixed fed infants aged one month and six months. Sixty term infants were enrolled from the labor ward of Valiasr Hospital between Oct 2011 and July 2015 and their fecal calprotectin was checked by the ELISA method and Hycult biotech kits. The enrolled infants had a birth weight of 2500-4000 g and no perinatal insults or hospitalization. Stool sampling was done at 1±1 week and at 6n±1 months. The six-month infants had no recent disease, antibiotic use or vaccination...
January 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28180127/impact-of-fecal-calprotectin-measurement-on-decision-making-in-children-with-inflammatory-bowel-disease
#8
Wael El-Matary, Esmail Abej, Vini Deora, Harminder Singh, Charles N Bernstein
BACKGROUND: The use of fecal calprotectin (FCal) as a marker of intestinal inflammation, in the management of inflammatory bowel disease (IBD) is increasing. The aim of this study was to examine the impact of FCal measurements on decision-making and clinical care of children with IBD. MATERIALS AND METHODS: In a retrospective cohort study, FCal, clinical activity indices, and blood markers were measured in children with established diagnoses of IBD. Pearson correlation coefficient analysis was performed to examine association between FCal and other markers...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28179407/calprotectin-as-a-biomarker-for-melioidosis-disease-progression-and-management
#9
Mohan Natesan, Enoka Corea, Shivankari Krishnananthasivam, Harindra Darshana Sathkumara, Jennifer L Dankmeyer, Beverly K Dyas, Kei Amemiya, Aruna Dharshan De Silva, Robert G Ulrich
Melioidosis is a neglected tropical disease that is caused by the bacterium Burkholderia pseudomallei, and is underreported in many endemic countries. A long and costly administration of antibiotics is required to clear infections, and there is an unmet need for biomarkers to guide antibiotic treatment and increase the number of patients that complete therapy. We identified calprotectin as a lead biomarker of Burkholderia pseudomallei infections, and examined correlations between this serum protein and antibiotic treatment outcomes of melioidosis patients...
February 8, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28175167/p604-usefulness-of-stool-hemoglobin-and-fecal-calprotectin-for-detecting-of-mild-to-moderate-ulcerative-colitis
#10
J S Koo, D J Kim, D-W Lee, Y J Jeen
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175112/p374-home-or-hospital-based-analysis-of-stool-calprotectin-assessing-two-methods-for-monitoring-inflammatory-bowel-disease
#11
A Heida, M Knol, A Muller Kobold, G Dijkstra, P van Rheenen
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175079/p319-accurate-cut-offs-for-predicting-endoscopic-activity-and-mucosal-healing-in-crohn-s-disease-with-fecal-calprotectin
#12
J M Vázquez-Morόn, B Benítez-Rodríguez, H Pallarés-Manrique, F H Machancoses, J L Robles Rodríguez, M Ramos-Lora, C Ruíz-Frutos
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175073/p282-does-colonoscopy-alter-the-post-procedural-fecal-calprotectin-results-in-crohn-s-disease-patients-with-ileocecal-resection
#13
Y Erzin, N Demir, S Bozcan, S Yıldırım, I Hatemi, A F Celik
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175067/p236-fecal-calprotectin-as-suitable-biomarker-in-evaluation-of-histological-disease-activity
#14
T Knezevic Ivanovski, S Knezevic Usaj, V Gligorijevic, S Markovic, P Svorcan, M Nedeljkovic Protic
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175055/p265-comparison-of-two-faecal-calprotectin-assays-in-monitoring-children-with-inflammatory-bowel-disease
#15
M Meglicka, M Szczepanski, J Bierla, M Dadalski, B Cukrowska, J Kierkus
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175049/p256-correlation-of-fecal-calprotectin-levels-with-endoscopic-severity-evaluated-with-balloon-assisted-endoscopy-in-patients-with-crohn-s-disease
#16
K Matsuoka, F Iwamoto, M Kimura, K Takenaka, T Fujii, M Nagahori, N Enomoto, K Ohtsuka, M Watanabe
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175043/p201-a-faecal-bacterial-markers-correlates-with-calprotectin-for-ibd-activity-monitoring
#17
J Amoedo, M Serra-Pagès, M Serrano, A Bahí, M Malagόn, P Gilabert, J Guardiola, D Busquets, J Garcia-Gil, X Aldeguer
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175037/p193-faecal-calprotectin-differentially-predicts-postoperative-endoscopic-recurrence-in-crohn-s-disease-according-to-therapy-a-prospective-multicenter-study
#18
C Verdejo Gil, A J Lucendo Villarin, D Hervías Cruz, Ó Roncero García-Escribano, A Bouhmidi, R Salmoral Luque, T Angueira, L Rincόn, I Salueña, R Lorente Poyatos
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175030/p148-fecal-calprotectin-as-a-noninvasive-indicator-for-ulcerative-colitis-disease-activity-in-the-korean-cohort
#19
S-H Lee, H Seo, K Chang, E M Song, G-U Kim, M Seo, E J Kwon, S W Hwang, S H Park, D-H Yang, K-J Kim, J-S Byeon, S-J Myung, S-K Yang, B D Ye
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175028/p214-what-is-the-diagnostic-accuracy-of-faecal-calprotectin-regarding-endoscopic-relapse-in-crohn-s-disease-patients-following-ileocecal-resection-a%C3%A2-tertiary-single-center-experience
#20
S Yıldırım, N Demir, S Bozcan, Y Erzin, I Hatemi, A F Celik
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
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