keyword
MENU ▼
Read by QxMD icon Read
search

Calprotectin

keyword
https://www.readbyqxmd.com/read/27923057/the-effect-of-iron-fortification-on-iron-fe-status-and-inflammation-a-randomized-controlled-trial
#1
Jingqiu Ma, Qianqian Sun, Jinrong Liu, Yanqi Hu, Shanshan Liu, Jie Zhang, Xiaoyang Sheng, K Michael Hambidge
BACKGROUND: Iron deficiency (ID) is common in toddlers in developing countries. Iron fortified or meat-based complementary foods may be effective to prevent ID. OBJECTIVE: Our objective was to compare iron status at 18 months and growth from 6 to 18 months in rural poor toddlers fed 3 different complementary foods. METHODS: The study was nested within a larger trial in which 6-month-old infants were randomized to receive 50g/d meat (MG), an equi-caloric fortified cereal supplement (FG) or local cereal supplement (LG) for 1 year...
2016: PloS One
https://www.readbyqxmd.com/read/27910113/diagnostic-accuracy-of-faecal-biomarkers-in-detecting-colorectal-cancer-and-adenoma-in-symptomatic-patients
#2
M M Widlak, C L Thomas, M G Thomas, C Tomkins, S Smith, N O'Connell, S Wurie, L Burns, C Harmston, C Evans, C U Nwokolo, B Singh, R P Arasaradnam
BACKGROUND: The diagnosis of colorectal cancer (CRC) can be difficult as symptoms are variable with poor specificity. Thus, there is a quest for simple, non-invasive testing that can help streamline those with significant colonic pathology. AIM: To assess using faecal immunochemical test for haemoglobin (FIT) or faecal calprotectin (FCP) to detect CRC and adenoma in symptomatic patients referred from primary care. METHODS: A total of 799 referred for urgent lower gastrointestinal investigations were prospectively recruited...
December 1, 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27905658/-lymphocytic-colitis-in-a-patient-with-ulcerative-colitis-report-of-one-case
#3
Camila Estay, Daniela Simian, Lilian Flores, Antonio Piottante, Rodrigo Quera
The relationship between Microscopic Colitis and Inflammatory Bowel Disease is unclear. However, when both are diagnosed they seem to be part of a broader spectrum of the same disease, more than just a coincidence. We report a 55 years old woman with Ulcerative Colitis limited to the rectum with complete clinical and endoscopic response to standard treatment and adequate surveillance for 13 years, who abandoned treatment and control. After eight years, she consulted for mild-to-moderate non-bloody diarrhea lasting several months...
August 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27902777/the-two-component-system-arlrs-and-alterations-in-metabolism-enable-staphylococcus-aureus-to-resist-calprotectin-induced-manganese-starvation
#4
Jana N Radin, Jessica L Kelliher, Paola K Párraga Solórzano, Thomas E Kehl-Fie
During infection the host imposes manganese and zinc starvation on invading pathogens. Despite this, Staphylococcus aureus and other successful pathogens remain capable of causing devastating disease. However, how these invaders adapt to host-imposed metal starvation and overcome nutritional immunity remains unknown. We report that ArlRS, a global staphylococcal virulence regulator, enhances the ability of S. aureus to grow in the presence of the manganese-and zinc-binding innate immune effector calprotectin...
November 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27898399/evaluation-of-an-automated-commercial-elisa-method-for-calprotectin-determination-in-pleural-fluid
#5
Lorena Vázquez-Iglesias, Pedro Casado-Rey, Maribel Botana-Rial, María Amalia Andrade-Olivié, Francisco Javier Rodriguez-Berrocal, María Páez de la Cadena, Alberto Fernández-Villar
No abstract text is available yet for this article.
November 29, 2016: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/27895392/determination-of-the-adequate-dosage-of-rebamipide-a-gastric-mucoprotective-drug-to-prevent-low-dose-aspirin-induced-gastrointestinal-mucosal-injury
#6
Kazuhiro Ota, Toshihisa Takeuchi, Sadaharu Nouda, Haruhiko Ozaki, Shinpei Kawaguchi, Yoshiaki Takahashi, Satoshi Harada, Shoko Edogawa, Yuichi Kojima, Takanori Kuramoto, Kazuhide Higuchi
Small intestinal mucosal injury caused by low-dose aspirin is a common cause of obscure gastrointestinal bleeding. We aimed to investigate the protective effects and optimal dose of rebamipide for low-dose aspirin-induced gastrointestinal mucosal injury. In this prospective randomized trial, 45 healthy volunteers (aged 20-65 years) were included and divided into three groups. The groups received enteric-coated aspirin 100 mg (low-dose aspirin) plus omeprazole 10 mg (Group A: proton pump inhibitor group), low-dose aspirin plus rebamipide 300 mg (Group B: standard-dose group), or low-dose aspirin plus rebamipide 900 mg (Group C: high-dose group)...
November 2016: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/27895095/calprotectin-in-rheumatic-diseases
#7
Francesca Ometto, Lara Friso, Davide Astorri, Costantino Botsios, Bernd Raffeiner, Leonardo Punzi, Andrea Doria
Calprotectin is a heterodimer formed by two proteins, S100A8 and S100A9, which are mainly produced by activated monocytes and neutrophils in the circulation and in inflamed tissues. The implication of calprotectin in the inflammatory process has already been demonstrated, but its role in the pathogenesis, diagnosis, and monitoring of rheumatic diseases has gained great attention in recent years. Calprotectin, being stable at room temperature, is a candidate biomarker for the follow-up of disease activity in many autoimmune disorders, where it can predict response to treatment or disease relapse...
November 28, 2016: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/27894337/intestinal-dysbiosis-is-common-in-systemic-sclerosis-and-associated-with-gastrointestinal-and-extraintestinal-features-of-disease
#8
Kristofer Andréasson, Zaid Alrawi, Anita Persson, Göran Jönsson, Jan Marsal
BACKGROUND: Recent evidence suggests a link between autoimmunity and the intestinal microbial composition in several rheumatic diseases including systemic sclerosis (SSc). The objective of this study was to investigate the prevalence of intestinal dysbiosis in SSc and to characterise patients suffering from this potentially immunomodulatory deviation. METHODS: This study consisted of 98 consecutive patients subject to in-hospital care. Stool samples were analysed for intestinal microbiota composition using a validated genome-based microbiota test (GA-map™ Dysbiosis Test, Genetic Analysis, Oslo, Norway)...
November 29, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27887637/clinical-improvement-and-reduction-in-serum-calprotectin-levels-after-an-intensive-exercise-programme-for-patients-with-ankylosing-spondylitis-and-non-radiographic-axial-spondyloarthritis
#9
Andrea Levitova, Hana Hulejova, Maja Spiritovic, Karel Pavelka, Ladislav Senolt, Marketa Husakova
BACKGROUND: The efficacy of exercise therapy for ankylosing spondylitis (AS) is well-documented, but dearth of information is for non-radiographic axial spondyloarthritis (nr-axSpA). Biomarkers like serum calprotectin, interleukins IL-6, IL-17 and tumour necrosis factor (TNF)-α may reflect the disease activity of axial spondyloarthritis (axSpA). In this study, we investigated clinical and laboratory parameters of both axSpA subgroups in response to intensive physical exercise. METHODS: Altogether, 46 patients with axSpA, characterised according to the Assessment of SpondyloArthritis International Society criteria as having nr-axSpA or AS underwent 6-month exercise programme...
November 25, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27887202/serological-markers-in-diagnosis-of-pediatric-inflammatory-bowel-disease-and-as-predictors-for-early-tumor-necrosis-factor-blocker-therapy
#10
Christine Olbjørn, Milada Cvancarova Småstuen, Espen Thiis-Evensen, Britt Nakstad, Morten Harald Vatn, Gøri Perminow
OBJECTIVE: To describe the prevalence of serological markers in newly diagnosed treatment-naïve pediatric inflammatory bowel disease (IBD), their utility in differentiating Crohn's disease (CD), ulcerative colitis (UC) and symptomatic non-IBD patients and whether serological markers are associated with early TNF blocker treatment. MATERIAL AND METHODS: Ninety-six children and adolescents <18 years, 58 with IBD and 38 symptomatic non-IBD controls were included...
November 25, 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27881072/patients-with-longstanding-ulcerative-colitis-in-remission-do-not-have-more-irritable-bowel-syndrome-like-symptoms-than-controls
#11
D Lundgren, J Rutegård, V Eklöf, R Palmqvist, P Karling
BACKGROUND: Irritable bowel syndrome (IBS) is more common in patients with ulcerative colitis (UC) than expected. The prevalence of IBS in patients with UC with longstanding disease is not known. We investigated the prevalence of IBS-like symptoms in patients with UC in remission and longstanding disease in comparison to control subjects. METHODS: Sixty-eight patients with UC and 33 patients with hereditary familiar colon cancer and who underwent colonoscopy surveillance were included...
November 24, 2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27881032/clinical-implications-of-assay-specific-differences-in-f-calprotectin-when-monitoring-inflammatory-bowel-disease-activity-over-time
#12
Karin Amcoff, Mats Stridsberg, Maria Lampinen, Anders Magnuson, Marie Carlson, Jonas Halfvarson
OBJECTIVE: With several faecal calprotectin (FC) assays on the market, it has been difficult to define a uniform threshold for discriminating between remission and active disease in patients with inflammatory bowel disease (IBD). We aimed to compare the results of different FC-assays in IBD patients, followed over time. MATERIAL AND METHODS: IBD patients provided faecal samples and reported clinical activity every third month prospectively over a two year period...
November 24, 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27862117/irritable-bowel-syndrome-and-active-inflammatory-bowel-disease-diagnosed-by-faecal-gas-analysis
#13
R B M Aggio, P White, H Jayasena, B de Lacy Costello, N M Ratcliffe, C S J Probert
BACKGROUND: Inflammatory bowel disease and irritable bowel syndrome may present in a similar manner. Measuring faecal calprotectin concentration is often recommended to rule out inflammatory bowel disease, however, there are no tests to positively diagnose irritable bowel syndrome and invasive tests are still used to rule out other pathologies. AIM: To investigate a platform technology for diagnosing inflammatory bowel disease and irritable bowel syndrome based on faecal gas...
January 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27856523/beyond-histological-remission-intramucosal-calprotectin-as-a-potential-predictor-of-outcomes-in-ulcerative-colitis
#14
Marianne Guirgis, Emily Wendt, Lai Mun Wang, Alissa Walsh, Daniel Burger, Robert V Bryant, Alex Kent, Rebecca Adamson, Oliver Brain, Simon P L Travis, Satish Keshav
BACKGROUND AND AIMS: Histological remission and low faecal calprotectin are positive prognostic factors in ulcerative colitis [UC]. Intramucosal calprotectin [iMC], which can be readily determined by immunohistochemistry, has not so far been evaluated as a predictor of outcome in UC. We aimed to investigate the relationship between iMC and clinical, endoscopic, and histological measures of remission in UC, and the independent prognostic value of iMC. METHODS: Ambulant patients with UC were recruited for a study comparing clinical activity indices...
November 14, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27849448/myeloid-related-protein-14-mrp-14-s100a9-calgranulin-b-is-associated-with-inflammation-in-proliferative-diabetic-retinopathy
#15
Ahmed M Abu El-Asrar, Kaiser Alam, Mohammad M Siddiquei, Kathleen Van den Eynde, Ghulam Mohammad, Gert De Hertogh, Ghislain Opdenakker
PURPOSE: To investigate the expression of the leukocyte proteins myeloid-related protein (MRP)-8 and MRP-14 in proliferative diabetic retinopathy (PDR) and the effect of MRP-8/MRP-14 (calprotectin) heterodimer on induction of proinflammatory factors in human retinal microvascular endothelial cells (HRMEC). METHODS: Epiretinal membranes from 20 patients with PDR and 10 patients with proliferative vitreoretinopathy (PVR), vitreous fluid samples from PDR and non-diabetic subjects and HRMEC were studied by immunohistochemistry and Western blot analysis...
November 16, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27848924/immunoanalytical-characteristics-of-fecal-calprotectin
#16
Cédric Desbène, Olivier Gaillard, Nathalie Kapel
Besides structural and physiological data of calprotectin, this paper points out the optimal conditions for sampling, fecal assays and interpretation of results.
December 1, 2016: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/27836422/surgical-necrotizing-enterocolitis
#17
REVIEW
Jamie R Robinson, Eric J Rellinger, L Dupree Hatch, Joern-Hendrik Weitkamp, K Elizabeth Speck, Melissa Danko, Martin L Blakely
Although currently available data are variable, it appears that the incidence of surgical necrotizing enterocolitis (NEC) has not decreased significantly over the past decade. Pneumoperitoneum and clinical deterioration despite maximal medical therapy remain the most common indications for operative treatment. Robust studies linking outcomes with specific indications for operation are lacking. Promising biomarkers for severe NEC include fecal calprotectin and S100A12; serum fatty acid-binding protein; and urine biomarkers...
November 8, 2016: Seminars in Perinatology
https://www.readbyqxmd.com/read/27834066/fecal-calprotectin-level-reflects-the-severity-of-clostridium-difficile-infection
#18
Jieun Kim, Heejung Kim, Hyun Ju Oh, Hyung Sun Kim, Youn Jee Hwang, Dongeun Yong, Seok Hoon Jeong, Kyungwon Lee
Clostridium difficile is a significant nosocomial and community-acquired pathogen, and is the leading cause of antibiotic-induced diarrhea associated with high morbidity and mortality. Given that the treatment outcome depends on the severity of C. difficile infection (CDI), we aimed to establish an efficient method of assessing severity, and focused on the stool biomarker fecal calprotectin (FC). FC directly reflects the intestinal inflammation status of a patient, and can aid in interpreting the current guidelines, which requires the integration of indirect laboratory parameters...
January 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/27832086/serum-calprotectin-discriminates-subclinical-disease-activity-from-ultrasound-defined-remission-in-patients-with-rheumatoid-arthritis-in-clinical-remission
#19
Jana Hurnakova, Hana Hulejova, Jakub Zavada, Martin Komarc, Petra Hanova, Martin Klein, Herman Mann, Olga Sleglova, Marta Olejarova, Sarka Forejtova, Olga Ruzickova, Jiri Vencovsky, Karel Pavelka, Ladislav Senolt
OBJECTIVE: Clinical remission in some patients with rheumatoid arthritis (RA) may be associated with ongoing synovial inflammation that is not always detectable on clinical examination or reflected by laboratory tests but can be visualized by musculoskeletal ultrasound. The goal of our study was to determine the levels of serum calprotectin, a major leukocyte protein, in patients with RA in clinical remission and to investigate the ability of serum calprotectin levels to distinguish patients in ultrasound-defined remission from those with residual ultrasound subclinical inflammation...
2016: PloS One
https://www.readbyqxmd.com/read/27824646/fecal-calprotectin-levels-are-closely-correlated-with-the-absence-of-relevant-mucosal-lesions-in-postoperative-crohn-s-disease
#20
Esther Garcia-Planella, Míriam Mañosa, Eduard Cabré, Laura Marín, Jordi Gordillo, Yamile Zabana, Jaume Boix, Sergio Sáinz, Eugeni Domènech
BACKGROUND: Fecal calprotectin (FC) is the best noninvasive biomarker of disease activity in inflammatory bowel disease. Its correlation with endoscopic mucosal lesions could save inconvenient, expensive, and repeated endoscopic examinations in particular clinical settings. PATIENTS AND METHODS: To assess the correlation between FC and the existence and severity of endoscopic postoperative recurrence (POR), a group of clinically stable outpatients with Crohn's disease for whom an ileocolonoscopy was routinely planned to assess POR were invited to collect a stool sample before starting bowel cleansing to measure FC...
December 2016: Inflammatory Bowel Diseases
keyword
keyword
26131
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"