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https://www.readbyqxmd.com/read/27920486/choroidal-and-skin-metastases-from-colorectal-cancer
#1
Joo Young Ha, Edward Hynseung Oh, Moon Ki Jung, Song Ee Park, Ji Tak Kim, In Gyu Hwang
Choroidal and skin metastasis of colon cancer is rare. In women, the frequency of cutaneous metastasis from colon cancer as the primary lesion in is 9% and skin metastasis occurs in 0.81% of all colorectal cancers. We report a patient with colonic adenocarcinoma who presented with visual disorder in her right eye and scalp pain as her initial symptoms. Contrast-enhance orbital magnetic resonance imaging with fat suppression revealed an infrabulbar mass, and skin biopsy of the posterior parietal scalp confirmed adenocarcinoma...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27904945/-sarcoidosis-and-uveitis-an-update
#2
REVIEW
J G Garweg
Ocular involvement in sarcoidosis is present in up to one third of patients and is frequently manifested before the underlying systemic disease has been diagnosed. With a view to the therapeutic consequences an early diagnosis of the underlying disease is advantageous. In cases of visual loss early diagnostic measures include invasive procedures, such as ultrasound-guided bronchoalveolar lavage and transbronchial biopsy, if nodular conjunctival or cutaneous manifestations which would confirm the diagnosis are not present...
November 30, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27893592/coughing-induced-suprachoroidal-hemorrhage-simulating-melanoma-in-two-cases
#3
Charlotte L Marous, Kareem Sioufi, Carol L Shields, Arman Mashayekhi, Jerry A Shields
PURPOSE: To describe two cases of coughing-induced suprachoroidal hemorrhage referred as choroidal melanoma. METHODS: Observational case reports. RESULTS: Two female patients (ages 54 and 60 years) were referred with possible choroidal melanoma. Both gave a history of 1 day of heavy coughing with Valsalva maneuver within 2 weeks before discovery of the tumor. In one case, the patient used anticoagulants for aortic valve replacement and the other patient used antiasthma medications...
November 23, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27843911/immunoglobulin-g4-related-ophthalmic-disease-involving-the-sclera-misdiagnosed-as-intraocular-tumor-report-of-one-case
#4
Hiroshi Goto, Shunichiro Ueda
AIMS: Immunoglobulin G4 (IgG4)-related disease is known to have diverse clinical manifestations. We report a case of IgG4-related ophthalmic disease misdiagnosed as intraocular tumor. METHODS: Case report. RESULTS: A 41-year-old man was referred to our department with a diagnosis of intraocular tumor, presumably choroidal melanoma. Although MR imaging was compatible with choroidal melanoma, he had been observed periodically without treatment because fundus findings were not typical of melanoma and visual function was preserved...
October 2016: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/27800275/uveal-melanoma-current-trends-in-diagnosis-and-management
#5
REVIEW
Berçin Tarlan, Hayyam Kıratlı
Uveal melanoma, which is the most common primary intraocular malignancy in adults, arises from melanocytes within the iris, ciliary body and choroid. The diagnosis is based principally on clinical examination of the tumor with biomicroscopy and indirect ophthalmoscopy and confirmed by diagnostic techniques such as ultrasonography, fundus fluorescein angiography and optical coherence tomography. The clinical diagnosis of posterior uveal melanomas can be made when the classical appearance of a pigmented dome-shaped mass is detected on dilated fundus exam...
June 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27785746/bilateral-multiple-choroidal-granulomas-and-systemic-vasculitis-as-presenting-features-of-tuberculosis-in-an-immunocompetent-patient
#6
Nitin Kumar, Sridharan Sudharshan, Sudha K Ganesh, Gopal Lingam, Jyotirmay Biswas
BACKGROUND: Multiple choroidal granulomas are a rare presentation of tuberculosis. Choroidal granulomas in immunocompetent patients can pose difficulty in diagnosis as in most cases systemic examination may not reveal any evidence of tuberculosis. We report a case of bilateral multiple choroidal granulomas with systemic vasculitis-like features and disseminated tuberculosis in an immunocompetent patient without pulmonary involvement. FINDINGS: A 26-year-old male Indian patient presented with bilateral blurred vision and systemic illness with vasculitis-like features...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27753657/a-comparative-immunohistochemical-study-of-epithelial-membrane-antigen-and-nherf1-ebp50-in-the-diagnosis-of-ependymomas
#7
Aruna Nambirajan, Mehar C Sharma, Madhu Rajeshwari, Aanchal Kakkar, Vaishali Suri, Chitra Sarkar
Ependymomas are gliomas that recapitulate normal ependymal cells. The epithelial membrane antigen (EMA) shows "dot-like" and "ring-like" staining patterns, highlighting "microlumens" or intracytoplasmic rosettes, a pathognomonic ultrastructural feature. NHERF1/EBP50, an adaptor protein localized at the apical plasma membrane of human epithelia, has been found to localize to these microlumens. We aimed to analyze the staining patterns of EMA and EBP50 in ependymomas and other tumors, and thereby compare their diagnostic utility...
October 7, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/27749454/nodulo-ulcerative-ocular-surface-squamous-neoplasia-in-6-patients-a-rare-presentation
#8
Swathi Kaliki, Suzanne K Freitag, James Chodosh
PURPOSE: To describe clinical presentation and histopathological features of a nodulo-ulcerative variant of ocular surface squamous neoplasia (OSSN). METHODS: Retrospective study. RESULTS: Six patients were identified with a nodulo-ulcerative variant of OSSN. Mean age at presentation was 56 years. One patient was immunosuppressed because of human immunodeficiency virus infection. The initial misdiagnosis was necrotizing scleritis/sclerokeratitis (n = 4), intraepithelial neoplasia (n = 1), and chalazion (n = 1)...
October 5, 2016: Cornea
https://www.readbyqxmd.com/read/27687936/distribution-of-feline-lymphoma-in-the-central-and-peripheral-nervous-systems
#9
REVIEW
Maria Teresa Mandara, Luca Motta, Pietro Calò
In cats, lymphoma (lymphosarcoma) is the most common neoplasm affecting the spinal cord and the second most common intracranial tumour. Although lymphoma commonly develops in the spinal cord as a part of a multicentric process, a primary form may occur. Lymphoma can exhibit a wide range of morphological patterns, including intraparenchymal brain mass, lymphomatosis cerebri, intravascular lymphoma, lymphomatous choroiditis and meningitis, extradural, intradural-extramedullary or intramedullary lymphoma in the spinal cord, or neurolymphomatosis in the peripheral nerves...
October 2016: Veterinary Journal
https://www.readbyqxmd.com/read/27673716/intraoperative-4-dimensional-microscope-integrated-optical-coherence-tomography-guided-27-gauge-transvitreal-choroidal-biopsy-for-choroidal-melanoma
#10
Dilraj S Grewal, Paramjit K Bhullar, Neel D Pasricha, Oscar M Carrasco-Zevallos, Christian Viehland, Brenton Keller, Liango Shen, Joseph A Izatt, Anthony N Kuo, Cynthia A Toth, Prithvi Mruthyunjaya
No abstract text is available yet for this article.
September 26, 2016: Retina
https://www.readbyqxmd.com/read/27560850/exophthalmos-diplopia-and-bilateral-eyelid-edema-symptoms-of-ocular-mastocytosis
#11
Arnaud Payerols, Eric Frouin, Aurélie Schiffmann, Nicolas Menjot de Champfleur, Danielle Canioni, Olivia Chandesris, Valérie Costes, Max Villain, Frédéric Mura
PURPOSE: Mastocytosis is characterized by clonal mast cell proliferation with accumulation within various organs and uncontrolled activation with excessive mast cell mediator release. Ocular manifestations have rarely been published. We describe a 63-year-old man with bilateral exophthalmos that led to the diagnosis of systemic mastocytosis. CASE REPORT: A patient presented with bilateral eyelid edema with exophthalmos associated with binocular diplopia. Ophthalmologic examination showed bilateral axial, symmetrical, and painless exophthalmos with eyelid edema, and limitation in elevation of the right eye...
August 24, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27488148/biopsy-techniques-for-intraocular-tumors
#12
REVIEW
Pukhraj Rishi, Abhinav Dhami, Jyotirmay Biswas
Biopsy involves the surgical removal of a tissue specimen for histopathologic evaluation. Most intraocular tumors are reliably diagnosed based on the clinical evaluation or with noninvasive diagnostic techniques. However, accurately diagnosing a small percentage of tumors can be challenging. A tissue biopsy is thus needed to establish a definitive diagnosis and plan the requisite treatment. From fine-needle aspiration biopsy (FNAB) to surgical excision, all tissue collection techniques have been studied in the literature...
June 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27399550/352%C3%A2-robot-assisted-endoscopic-third-ventriculostomy
#13
Reid Hoshide, Mark Calayag, Hal S Meltzer, Michael L Levy, David D Gonda
INTRODUCTION: Endoscopic third ventriculostomy (ETV) is an established and effective treatment for obstructive hydrocephalus. In its most common application, surgeons plan their entry point and endoscope trajectory for the procedure based on anatomic landmarks, then free-handedly control the endoscope. We have introduced the Rosa robot assistance to our ETV procedure to stereotactically optimize endoscope trajectories, to reduce risk of traction on neural structures by the endoscope, and to provide a stable mechanical holder of the endoscope...
August 2016: Neurosurgery
https://www.readbyqxmd.com/read/27324683/prognostic-biopsy-of-choroidal-melanoma-after-proton-beam-radiation-therapy
#14
Rumana N Hussain, Helen Kalirai, Carl Groenewald, Andrzej Kacperek, R Douglas Errington, Sarah Ellen Coupland, Heinrich Heimann, Bertil Damato
No abstract text is available yet for this article.
October 2016: Ophthalmology
https://www.readbyqxmd.com/read/27315323/ocular-manifestations-of-monoclonal-immunoglobulin-light-chain-deposition-disease
#15
Elona Dhrami-Gavazi, K Bailey Freund, Winston Lee, Ben Z Cohen, Surya V Seshan, Lawrence A Yannuzzi
PURPOSE: To demonstrate unusual retinal findings in a patient with progressive renal failure due to idiopathic monoclonal immunoglobulin light chain deposition disease, using multimodal imaging. METHODS: Observational case report of a 43-year-old white man with renal failure due to light chain deposition disease. His course over 6 years was documented with multimodal imaging including fundus photography, fundus autofluorescence, fluorescein angiography, and spectral domain optical coherence tomography...
June 16, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27258541/tattoo-associated-uveitis-with-choroidal-granuloma-a-rare-presentation-of-systemic-sarcoidosis
#16
Vivek B Pandya, Claire Y Hooper, Rohan Merani, Peter McCluskey
PURPOSE: The authors report a rare case of systemic sarcoidosis manifesting as bilateral granulomatous panuveitis and multiple tattoo granulomas. METHODS: Case report. RESULTS: A 30-year-old man presented with headaches, ocular pain, photophobia, and blurred vision. He was found to have significant skin inflammation, predominantly involving areas of tattoos. Fundoscopic examination revealed bilateral granulomatous panuveitis with small focal choroidal lesions...
June 2, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27239068/a-case-of-choroidal-melanoma-metastatic-to-the-breast
#17
L Taran-Munteanu, A Hartkopf, T K Eigentler, U Vogel, S Brucker, F A Taran
A 61-year-old woman developed blurred vision in her left eye in December 2006. A clinical diagnosis of choroidal melanoma was made. The patient underwent excision of the left lens, followed by vitrectomy and stereotactic radiotherapy. She remained systemically healthy until 50 months later when, during a CT scan done for staging purposes, a newly visible lump was noted in the lower quadrant of her left breast. Core needle biopsy of the lesion in the left breast was performed, and histologic examination revealed metastasis from the choroidal melanoma...
May 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/27191355/clinical-features-of-ocular-sarcoidosis-in-patients-with-biopsy-proven-pulmonary-sarcoidosis-in-serbia
#18
Aleksandra Radosavljević, Vesna Jakšić, Lato Pezo, Dragana Kovačević-Pavićević, Aleksandra Ilić, Violeta Mihailović Vučinić
PURPOSE: To analyze clinical characteristics of ocular sarcoidosis in a group of biopsy-proven sarcoid patients treated at the single referral center for sarcoidosis in Serbia. METHODS: A prospective study carried out on 88 biopsy-proven sarcoid patients between January 2012 and December 2014. All patients underwent complete ophthalmological examination. RESULTS: Ocular sarcoidosis was present in 32 patients (36.4% of all) and included: eyelid skin lesions (2...
May 18, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27172390/features-of-cutaneous-malignant-melanoma-metastatic-to-the-retina-and-vitreous
#19
Mark P Breazzano, Ann E Barker-Griffith
BACKGROUND/AIMS: To report a case of cutaneous malignant melanoma with cerebral metastasis found to have vitreoretinal metastasis upon referral for neovascular glaucoma. METHODS: The clinical history and ocular examination findings, including histologic, cytologic, genetic, and immunohistochemical features of the vitreoretinal metastatic tumor, were reviewed. Additionally, the histologic and immunohistochemical features of the primary skin tumor and brain metastasis were also assessed...
December 2015: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/27171574/pulmonary-adenocarcinoma-metastatic-to-the-choroid-diagnosed-by-biopsy-of-an-extrascleral-nodule
#20
Frederick A Jakobiec, David J Ramsey, Anna M Stagner, David M Wu, Michael K Yoon
PURPOSE/BACKGROUND: To report a patient with orbital extension of a choroidal metastasis produced by a pulmonary adenocarcinoma which was diagnosed by biopsy of the extrascleral nodule. METHODS: Clinical history and imaging studies (including fundus photography, autofluorescence, fluorescein angiography, B-scan, and orbital MRI) were reviewed along with histopathologic and immunohistochemical studies. RESULTS: A 60-year-old woman presented with decreased vision in the right eye...
September 2015: Ocular Oncology and Pathology
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