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Muscle protein intake

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https://www.readbyqxmd.com/read/29342124/the-root-of-atractylodes-macrocephala-koidzumi-prevents-obesity-and-glucose-intolerance-and-increases-energy-metabolism-in-mice
#1
Mi Young Song, Soo-Kyoung Lim, Jing-Hua Wang, Hojun Kim
Targeting energy expenditure offers a strategy for treating obesity more effectively and safely. In previous studies, we found that the root of Atractylodes macrocephala Koidzumi (Atractylodis Rhizoma Alba, ARA) increased energy metabolism in C2C12 cells. Here, we investigated the effects of ARA on obesity and glucose intolerance by examining energy metabolism in skeletal muscle and brown fat in high-fat diet (HFD) induced obese mice. ARA decreased body weight gain, hepatic lipid levels and serum total cholesterol levels, but did not modify food intake...
January 17, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29339696/chronic-ethanol-increases-calcium-calmodulin-dependent-protein-kinaseii%C3%AE-gene-expression-and-decreases-monoamine-oxidase-amount-in-rat-heart-muscles-rescue-effect-of-zingiber-officinale-ginger-extract
#2
Elaheh Heshmati, Alireza Shirpoor, Fatemeh Kheradmand, Mohammad Alizadeh, Farzaneh Hosseini Gharalari
OBJECTIVE: Association between chronic alcohol intake and cardiac abnormality is well known; however, the precise underlying molecular mediators involved in ethanol-induced heart abnormalities remain elusive. This study investigated the effect of chronic ethanol exposure on calcium/calmodulin-dependent protein kinase IIδ (CaMKIIδ) gene expression and monoamine oxidase (MAO) levels and histological changes in rat heart. It was also planned to find out whether Zingiber officinale (ginger) extract mitigated the abnormalities induced by ethanol in rat heart...
January 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29337071/lower-protein-and-higher-carbohydrate-intake-is-related-with-altering-metabolic-syndrome-components-in-elderly-women-a-cross-sectional-study
#3
Hellen C G Nabuco, Crisieli M Tomeleri, Paulo Junior Sugihara, Rodrigo Dos Reis Fernandes, Edilaine F Cavalcante, Melissa Antunes, Roberto Carlos Burini, Danielle Venturini, Décio S Barbosa, Analiza Mônica Silva, Edilson S Cyrino
BACKGROUND: Metabolic Syndrome (MetS) is an energy-disturbance disease associated with insulin resistance. Hence, the intake of energy-rich macronutrients might affect some MetS components. The aim of this study was to explore the association of ingested macronutrients with MetS components in older women. METHODS: A cross sectional study was conducted in 245 older women (≥60 years). Whole-body dual-energy X-ray absorptiometry was used to assess total body fat, percentage body fat (absolute and relative), and skeletal muscle mass...
January 11, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29332935/novel-treatment-strategies-for-chronic-kidney-disease-insights-from-the-animal-kingdom
#4
REVIEW
Peter Stenvinkel, Johanna Painer, Makoto Kuro-O, Miguel Lanaspa, Walter Arnold, Thomas Ruf, Paul G Shiels, Richard J Johnson
Many of the >2 million animal species that inhabit Earth have developed survival mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration and vascular ageing; however, some animals remain susceptible to these complications. Domestic and captive wild felids, for example, show susceptibility to chronic kidney disease (CKD), potentially linked to the high protein intake of these animals. By contrast, naked mole rats are a model of longevity and are protected from extreme environmental conditions through mechanisms that provide resistance to oxidative stress...
January 15, 2018: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/29314721/peritoneal-protein-losses-depend-on-more-than-just-peritoneal-dialysis-modality-and-peritoneal-membrane-transporter-status
#5
Suree Yoowannakul, Lauren S Harris, Andrew Davenport
Peritoneal protein clearance (PPCl) depends upon vascular supply and size selective permeability. Some previous reports suggested PPCl can distinguish fast peritoneal membrane transport due to local or systemic inflammation. However, as studies have been discordant, we wished to determine factors associated with an increased PPCl. Consecutive patients starting peritoneal dialysis (PD) who were peritonitis-free were studied. Data included a baseline peritoneal equilibration test (PET), measurement of dialysis adequacy, 24-h dialysate PPCl and body composition measured by multifrequency bioimpedance...
January 4, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29313445/body-composition-metabolism-sleep-psychological-and-eating-patterns-of-overtraining-syndrome-results-of-the-eros-study-eros-profile
#6
Flavio A Cadegiani, Claudio E Kater
Overtraining syndrome (OTS) is caused by an imbalance between training, nutrition and resting, and leads to decreased performance and fatigue; however, the precise underlying triggers of OTS remain unclear. This study investigated the body composition, metabolism, eating, sleeping patterns and mood states among participants with OTS. Selected participants were divided into OTS-affected athletes (OTS, n = 14), healthy athletes (ATL, n = 25), and healthy non-physically active controls (NCS, n = 12). Compared to ATL, OTS showed decreased sleep quality (p = 0...
January 9, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29304744/a-randomised-controlled-intervention-study-investigating-the-efficacy-of-carotenoid-rich-fruits-and-vegetables-and-extra-virgin-olive-oil-on-attenuating-sarcopenic-symptomology-in-overweight-and-obese-older-adults-during-energy-intake-restriction-protocol-paper
#7
Anthony Villani, Hattie Wright, Gary Slater, Jonathan Buckley
BACKGROUND: Weight loss interventions have not been advocated for overweight/obese older adults due to potential loss of skeletal muscle and strength impacting on physical function with potential loss of independence. Carotenoids and polyphenols are inversely associated with sarcopenic symptomology. This paper reports the protocol of a study evaluating the efficacy of a high-protein, energy restricted diet rich in carotenoids and polyphenols on body composition, muscle strength, physical performance and quality of life in overweight and obese older adults...
January 5, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29301606/epac2a-knockout-mice-are-resistant-to-dexamethasone-induced-skeletal-muscle-atrophy-and-short-term-cold-stress
#8
Seung-Eun Song, Su-Kyung Shin, So-Young Park, Il-Seon Hwang, Seung-Soon Im, Jae-Hoon Bae, Myung-Sook Choi, Dae-Kyu Song
Exchange protein directly activated by cAMP (Epac) 2a-knockout (KO) mice exhibit accelerated diet-induced obesity and are resistant to leptin-mediated adipostatic signaling from the hypothalamus to adipose tissue, with sustained food intake. However, the impact of Epac2a deficiency on hypothalamic regulation of sympathetic nervous activity (SNA) has not been elucidated. This study was performed to elucidate the response of Epac2a-KO mice to dexamethasone-induced muscle atrophy and acute cold stress. Compared to age-matched wild-type mice, Epac2a-KO mice showed higher energy expenditures and expression of myogenin and uncoupling protein-1 in skeletal muscle (SM) and brown adipose tissue (BAT), respectively...
January 5, 2018: BMB Reports
https://www.readbyqxmd.com/read/29300423/effects-of-low-dose-dairy-protein-plus-micronutrient-supplementation-during-resistance-exercise-on-muscle-mass-and-physical-performance-in-older-adults-a-randomized-controlled-trial
#9
S Seino, K Sumi, M Narita, Y Yokoyama, K Ashida, A Kitamura, S Shinkai
OBJECTIVES: To investigate whether supplementation with low-dose dairy protein plus micronutrients augments the effects of resistance exercise (RE) on muscle mass and physical performance compared with RE alone among older adults. DESIGN: Randomized controlled trial. SETTING: Tokyo, Japan. PARTICIPANTS: Eighty-two community-dwelling older adults (mean age, 73.5 years) were randomly allocated to an RE plus dairy protein and micronutrient supplementation group or an RE only group (n = 41 each)...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29295596/small-intestinal-absorption-of-methylsulfonylmethane-msm-and-accumulation-of-the-sulfur-moiety-in-selected-tissues-of-mice
#10
Thomas Wong, Richard J Bloomer, Rodney L Benjamin, Randal K Buddington
The principal dietary sources of sulfur, the amino acids methionine and cysteine, may not always be consumed in adequate amounts to meet sulfur requirements. The naturally occurring organosulfur compound, methylsulfonylmethane (MSM), is available as a dietary supplement and has been associated with multiple health benefits. Absorption of MSM by the small intestine and accumulation of the associated sulfur moiety in selected tissues with chronic (8 days) administration were evaluated using juvenile male mice...
December 25, 2017: Nutrients
https://www.readbyqxmd.com/read/29288718/kr%C3%A3-ppel-like-factor-15-regulator-of-bcaa-metabolism-and-circadian-protein-rhythmicity
#11
REVIEW
Liyan Fan, Paishiun N Hsieh, David R Sweet, Mukesh K Jain
Regulation of nutrient intake, utilization, and storage exhibits a circadian rhythmicity that allows organisms to anticipate and adequately respond to changes in the environment across day/night cycles. The branched-chain amino acids (BCAAs) leucine, isoleucine, and valine are important modulators of metabolism and metabolic health - for example, their catabolism yields carbon substrates for gluconeogenesis during periods of fasting. Krüppel-like factor 15 (KLF15) has recently emerged as a critical transcriptional regulator of BCAA metabolism, and the absence of this transcription factor contributes to severe pathologies such as Duchenne muscular dystrophy and heart failure...
December 27, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29285709/effects-of-dried-tofu-supplementation-during-interval-walking-training-on-the-methylation-of-the-nfkb2-gene-in-the-whole-blood-of-older-women
#12
Mayuko Morikawa, Sakura Nakano, Nobuo Mitsui, Hisashi Murasawa, Shizue Masuki, Hiroshi Nose
Muscle atrophy with aging is closely associated with chronic systemic inflammation and lifestyle-related diseases. Here, we assessed whether dried tofu intake during 5-month interval walking training (IWT) enhanced increases in thigh muscle mass and strength and ameliorated susceptibility to inflammation in older women. Subjects (n = 32, ~ 65 years) who performed IWT for > 6 months participated in this study. They were randomly divided into 2 groups: IWT + placebo intake (PLG, n = 16; 108 kcal, 0...
December 29, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29278646/impact-of-dietary-nutrient-intake-and-physical-activity-on-body-composition-and-growth-in-indian-children
#13
Anuradha V Khadilkar, Shashi A Chiplonkar, Neha A Kajale, Veena H Ekbote, Lavanya Parathasarathi, Raja Padidela, Vaman V Khadilkar
OBJECTIVE: To investigate inter-relationships of dietary-composition and physical activity (PA) with growth and BC in urban Indian school-children. METHODS: A cross-sectional study was performed in 4747-Indian school children (2623- Boys) aged 3-18 year. Weight, height, BC by body impedance analyser, PA and dietary food intakes by questionnaire method were recorded. RESULTS: Mean daily energy and protein intakes as Recommended Dietary Allowance (RDA) were significantly lower in both boys and girls (P<0...
December 20, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29247922/analysis-of-meat-quality-traits-and-gene-expression-profiling-of-pigs-divergent-in-residual-feed-intake
#14
Justyna Horodyska, Michael Oster, Henry Reyer, Anne Maria Mullen, Peadar G Lawlor, Klaus Wimmers, Ruth M Hamill
Residual feed intake (RFI), the difference between actual feed intake and predicted feed requirements, is suggested to impact various aspects of meat quality. The objective of this study was to investigate the molecular mechanisms underpinning the relationship between RFI and meat quality. Technological, sensory and nutritional analysis as well as transcriptome profiling were carried out in Longissimus thoracis et lumborum muscle of pigs divergent in RFI (n=20). Significant differences in sensory profile and texture suggest a minor impairment of meat quality in more efficient pigs...
November 20, 2017: Meat Science
https://www.readbyqxmd.com/read/29247679/anti-leptin-receptor-antibodies-strengthen-leptin-biofunction-in-growing-chickens
#15
M M Lei, C K Wei, Z Chen, S Yosefi, H X Zhu, Z D Shi
Antibodies against the extracellular domains of the chicken leptin receptor were used to study the biological function of leptin in growing chickens. Both polyclonal and monoclonal antibodies were administered intramuscularly to 30-d-old Chinese indigenous Gushi pullets. Both antibody preparations increased feed intake for 6 h after injection and reduced plasma concentrations of glucose, triglycerides, and both high- and low-density lipoproteins. The antibody treatments also upregulated agouti-related peptide and neuropeptide Y in the hypothalamus and downregulated proopiomelanocortin, melanocortin 4 receptor, and leptin receptor...
December 13, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29245988/alcohol-intake-aggravates-adipose-browning-and-muscle-atrophy-in-cancer-associated-cachexia
#16
Bo Wang, Faya Zhang, Hui Zhang, Zhixiu Wang, Yan-Nan Ma, Mei-Jun Zhu, Min Du
Cancer is commonly associated with cachexia, a paraneoplastic syndrome characterized by body weight loss, muscle wasting, adipose tissue atrophy and inflammation. Chronic alcohol consumption increases the risk of multiple types of cancer, and enhances cancer-associated cachexia (CAC), but the underlying mechanisms remain poorly defined. To test, C57BL/6 mice were fed with 0% or 20% (w/v) alcohol for 3 months, then inoculated with B16BL6 melanoma cells subcutaneously in the right side of the hip and continued to feed with/without alcohol for 3 or 4 weeks...
November 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/29240672/amount-distribution-and-quality-of-protein-intake-are-not-associated-with-muscle-mass-strength-and-power-in-healthy-older-adults-without-functional-limitations-an-enable-study
#17
Anne Gingrich, Alexandra Spiegel, Robert Kob, Daniel Schoene, Thomas Skurk, Hans Hauner, Cornel C Sieber, Dorothee Volkert, Eva Kiesswetter
To maintain muscle mass in older age, several aspects regarding the amount and distribution of protein intake have been suggested. Our objective was to investigate single and combined associations of daily protein intake, evenness of protein distribution across the three main meals, number of meals providing ≥0.4 g protein/kg body weight (BW), and number of meals providing ≥2.5 g leucine, with muscle mass, strength, and power in successful agers. In this cross-sectional study in 97 healthy community-dwelling adults without functional limitations aged 75-85 years, protein intake was assessed using 7-day food records...
December 14, 2017: Nutrients
https://www.readbyqxmd.com/read/29232264/fish-oil-derived-n-3-polyunsaturated-fatty-acids-for-the-prevention-and-treatment-of-sarcopenia
#18
Stuart R Gray, Bettina Mittendorfer
PURPOSE OF REVIEW: Muscle mass and function decline progressively starting in middle age, which can result in sarcopenia and affect people's mobility and independence later in life. Exercise training and increased protein intake are typically recommended to counteract the age-associated decline in muscle mass and function. However, few people comply with exercise recommendations and the effectiveness of high-protein intake to halt the decline in muscle mass and function has not been proven...
December 9, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29225317/pre-exercise-high-fat-diet-for-3-days-affects-post-exercise-skeletal-muscle-glycogen-repletion
#19
Yumiko Takahashi, Yutaka Matsunaga, Yuki Tamura, Shin Terada, Hideo Hatta
Previous studies have shown that the short-term intake of a high-fat diet (HFD) impairs glucose metabolism. In this study, we investigated the influences of pre-exercise HFD intake for 3 d on post-exercise glycogen repletion in skeletal muscle in ICR mice. Mice received either an HFD (57% kcal from fat, 23% kcal from carbohydrate; HFD group) or standard laboratory chow (13% kcal from fat, 60% kcal from carbohydrate; Con group) for 3 d before exercise. Mice performed treadmill running at 25 m/min for 60 min and were orally administered a glucose (2 mg/g body weight) solution immediately after and at 60 min after exercise...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29225213/fish-protein-hydrolysate-exhibits-anti-obesity-activity-and-reduces-hypothalamic-neuropeptide-y-and-agouti-related-protein-mrna-expressions-in-rats
#20
Takafumi Mizushige, Masaki Komiya, Moe Onda, Kenji Uchida, Kohsuke Hayamizu, Yukihito Kabuyama
Fish protein is a source of animal protein that is consumed worldwide. Although it has been reported that the intake of Alaska pollack protein (APP) reduces body fat accumulation and increases muscle weight in rats, the mechanisms underlying these effects are poorly understood. As a possibility, peptides released from APP in the gastrointestinal tract are important to the functions of APP. In the present study, we examined the effects of APP hydrolysate digested artificially with pepsin and pancreatin on white adipose tissue and skeletal muscle...
2017: Biomedical Research
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