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Muscle protein intake

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https://www.readbyqxmd.com/read/28335426/elevated-serum-hepcidin-levels-during-an-intensified-training-period-in-well-trained-female-long-distance-runners
#1
Aya Ishibashi, Naho Maeda, Daichi Sumi, Kazushige Goto
Iron is essential for providing oxygen to working muscles during exercise, and iron deficiency leads to decreased exercise capacity during endurance events. However, the mechanism of iron deficiency among endurance athletes remains unclear. In this study, we compared iron status between two periods involving different training regimens. Sixteen female long-distance runners participated. Over a seven-month period, fasting blood samples were collected during their regular training period (LOW; middle of February) and during an intensified training period (INT; late of August) to determine blood hematological, iron, and inflammatory parameters...
March 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28328712/resistance-training-induced-elevations-in-muscular-strength-in-trained-men-are-maintained-after-2-weeks-of-detraining-and-not-differentially-affected-by-whey-protein-supplementation
#2
Paul S Hwang, Thomas L Andre, Sarah K McKinley-Barnard, Flor E Morales Marroquín, Joshua J Gann, Joon J Song, Darryn S Willoughby
Hwang, PS, Andre, TL, McKinley-Barnard, SK, Morales Marroquín, FE, Gann, JJ, Song, JJ, and Willoughby, DS. Resistance training-induced elevations in muscular strength in trained men are maintained after 2 weeks of detraining and not differentially affected by whey protein supplementation. J Strength Cond Res 31(4): 869-881, 2017-Resistance training (RT) with nutritional strategies incorporating whey protein intake postexercise can stimulate muscle protein synthesis and elicit hypertrophy. The early phases of training-induced anabolic responses can be attenuated with longer-term training...
April 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28327084/a-transcriptome-multi-tissue-analysis-identifies-biological-pathways-and-genes-associated-with-variations-in-feed-efficiency-of-growing-pigs
#3
Florence Gondret, Annie Vincent, Magalie Houée-Bigot, Anne Siegel, Sandrine Lagarrigue, David Causeur, Hélène Gilbert, Isabelle Louveau
BACKGROUND: Animal's efficiency in converting feed into lean gain is a critical issue for the profitability of meat industries. This study aimed to describe shared and specific molecular responses in different tissues of pigs divergently selected over eight generations for residual feed intake (RFI). RESULTS: Pigs from the low RFI line had an improved gain-to-feed ratio during the test period and displayed higher leanness but similar adiposity when compared with pigs from the high RFI line at 132 days of age...
March 21, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28320046/increased-insulin-resistance-and-glucagon-levels-in-mild-inactive-systemic-lupus-patients-despite-normal-glucose-tolerance
#4
Cíntia Nh Miyake, Bruno Gualano, Wagner S Dantas, Renato T Pereira, William Neves, Vanessa O Zambelli, Samuel K Shinjo, Rosa M Pereira, Elizabeth R Silva, Ana Lúcia Sá-Pinto, Eduardo Borba, Hamilton Roschel, Eloisa Bonfá, Fabiana B Benatti
OBJECTIVE: To assess insulin sensitivity in patients with systemic lupus erythematosus (SLE) in response to a meal tolerance test (MTT). METHODS: In this cross-sectional study, 33 adult females mild/inactive SLE and 16 age- and body mass index (BMI)-matched female healthy controls (CTRL) underwent a MTT and were assessed for insulin sensitivity and beta-cell function. Skeletal muscle protein expressions of total and membrane GLUT-4 were also evaluated (SLE, n=10; CTRL, n=5); muscle biopsies were performed after MTT...
March 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28318687/protein-intake-distribution-pattern-does-not-affect-anabolic-response-lean-body-mass-muscle-strength-or-function-over-8-weeks-in-older-adults-a-randomized-controlled-trial
#5
Il-Young Kim, Scott Schutzler, Amy M Schrader, Horace J Spencer, Gohar Azhar, Robert R Wolfe, Arny A Ferrando
BACKGROUND & AIMS: In our recent acute metabolic study, we found no differences in the anabolic response to differing patterns of dietary protein intake. To confirm this in a chronic study, we investigated the effects of protein distribution pattern on functional outcomes and protein kinetics in older adults over 8 weeks. METHODS: To determine chronic effects of protein intake pattern at 1.1 g protein/kg/day in mixed meals on lean body mass (LBM), functional outcomes, whole body protein kinetics and muscle protein fractional synthesis rate (MPS) over 8-week respective dietary intervention, fourteen older subjects were randomly divided into either EVEN or UNVEN group...
March 3, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28314293/assessment-of-nutritional-and-inflammatory-status-to-determine-the-prevalence-of-malnutrition-in-patients-undergoing-surgery-for-colorectal-carcinoma
#6
Antonella Daniele, Rosa Divella, Ines Abbate, Addolorata Casamassima, Vito Michele Garrisi, Eufemia Savino, Porzia Casamassima, Eustachio Ruggieri, Raffaele DE Luca
BACKGROUND/AIM: Colorectal Cancer is the fourth most frequent cause of cancer death worldwide and its incidence increases from 50 years of age. It is often associated with protein-caloric malnutrition and 20% of cancer deaths occur due to this event. The aim of this study was to assess the prevalence of malnutrition and inflammatory status in 78 patients undergoing surgery for colorectal carcinoma. PATIENTS AND METHODS: Nutritional Status was assessed by Mini Nutritional Assessment (MNA)...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28285641/effectiveness-of-essential-amino-acid-supplementation-in-stimulating-whole-body-net-protein-anabolism-is-comparable-between-copd-patients-and-healthy-older-adults
#7
Renate Jonker, Nicolaas Ep Deutz, Marcia L Erbland, Paula J Anderson, Mariëlle Pkj Engelen
BACKGROUND: The development of effective nutritional strategies in support of muscle growth for patients with chronic obstructive pulmonary disease (COPD) remains challenging. Dietary essential amino acids (EAAs) are the main driver of postprandial net protein anabolism. In agreement, EAA supplements in healthy older adults are more effective than supplements with the composition of complete proteins. In patients with COPD it is still unknown whether complete protein supplements can be substituted with only EAAs, and whether they are as effective as in healthy older adults...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28282858/the-impact-of-shiftwork-on-skeletal-muscle-health
#8
REVIEW
Brad Aisbett, Dominique Condo, Evelyn Zacharewicz, Séverine Lamon
(1) Background: About one in four workers undertake shift rosters that fall outside the traditional 7 a.m.-6 p.m. scheduling. Shiftwork alters workers' exposure to natural and artificial light, sleep patterns, and feeding patterns. When compared to the rest of the working population, shiftworkers are at a greater risk of developing metabolic impairments over time. One fundamental component of metabolic health is skeletal muscle, the largest organ in the body. However, cause-and-effect relationships between shiftwork and skeletal muscle health have not been established; (2) Methods: A critical review of the literature was completed using online databases and reference lists; (3) Results: We propose a conceptual model drawing relationships between typical shiftwork consequences; altered light exposure, sleep patterns, and food and beverage consumption, and drivers of skeletal muscle health-protein intake, resistance training, and hormone release...
March 8, 2017: Nutrients
https://www.readbyqxmd.com/read/28278204/sarcolipin-deletion-exacerbates-soleus-muscle-atrophy-and-weakness-in-phospholamban-overexpressing-mice
#9
Val A Fajardo, Daniel Gamu, Andrew Mitchell, Darin Bloemberg, Eric Bombardier, Paige J Chambers, Catherine Bellissimo, Joe Quadrilatero, A Russell Tupling
Sarcolipin (SLN) and phospholamban (PLN) are two small proteins that regulate the sarco(endo)plasmic reticulum Ca2+-ATPase pumps. In a recent study, we discovered that Pln overexpression (PlnOE) in slow-twitch type I skeletal muscle fibers drastically impaired SERCA function and caused a centronuclear myopathy-like phenotype, severe muscle atrophy and weakness, and an 8 to 9-fold upregulation of SLN protein in the soleus muscles. Here, we sought to determine the physiological role of SLN upregulation, and based on its role as a SERCA inhibitor, we hypothesized that it would represent a maladaptive response that contributes to the SERCA dysfunction and the overall myopathy observed in the PlnOE mice...
2017: PloS One
https://www.readbyqxmd.com/read/28270867/gene-expression-is-differentially-regulated-in-skeletal-muscle-and-circulating-immune-cells-in-response-to-an-acute-bout-of-high-load-strength-exercise
#10
Gyrd O Gjevestad, Håvard Hamarsland, Truls Raastad, Inger Ottestad, Jacob J Christensen, Kristin Eckardt, Christian A Drevon, Anne S Biong, Stine M Ulven, Kirsten B Holven
BACKGROUND: High-intensity exercise induces many metabolic responses. In is unknown whether the response in the peripheral blood mononuclear cells (PBMCs) reflects the response in skeletal muscle and whether mRNA expression after exercise can be modulated by nutritional intake. The aims were to (i) investigate the effect of dairy proteins on acute responses to exercise in skeletal muscle and PBMCs measuring gene expression and (ii) compare this response in young and older subjects. METHODS: We performed two separate studies in young (20-40 years) and older subjects (≥70 years)...
2017: Genes & Nutrition
https://www.readbyqxmd.com/read/28265682/-influence-of-skeletal-muscles-on-the-risk-of-falling-in-old-age
#11
D Schöne, E Freiberger, C C Sieber
Falls in older adults are a major public health problem, affecting 1 in 3 persons aged 65 and over at least once a year. Consequences of falling include death, injuries, fear of falling, and subsequent loss of independence. The age-related loss of muscle mass and function (sarcopenia) as well as muscle strength are markers of the frailty syndrome. In addition, they are associated with physical function and are a risk factor for falling. Older adults should be screened for falls at least annually. If evaluated as at-risk, a comprehensive falls assessment should be conducted to determine an individual's risk profile...
March 6, 2017: Der Internist
https://www.readbyqxmd.com/read/28259478/comparison-of-equations-of-resting-and-total-energy-expenditure-in-peritoneal-dialysis-patients-using-body-composition-measurements-determined-by-multi-frequency-bioimpedance
#12
Sally El-Kateb, Sivakumar Sridharan, Ken Farrington, Stanley Fan, Andrew Davenport
BACKGROUND & AIMS: Waste products of metabolism accumulate in patients with kidney failure and it has been proposed that the amount of dialysis treatment patients require be adjusted for energy expenditure. This requires validation of methods to estimate energy expenditure in dialysis patients. METHODS: We compared values of resting energy expenditure (REE) estimated in peritoneal dialysis (PD) patients using a selection of available equations with estimates derived using a novel equation recently validated in chronic kidney disease patients (CKD equation)...
February 17, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28258495/dietary-protein-intake-is-strongly-and-positively-related-with-muscle-strength-in-patients-with-pre-dialysis-chronic-kidney-disease
#13
Koji Hiraki, Chiharu Hotta, Kazuhiro P Izawa, Tsutomu Sakurada, Yugo Shibagaki
No abstract text is available yet for this article.
March 3, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28252552/effects-of-resistance-training-and-protein-supplementation-in-breast-cancer-survivors
#14
Takudzwa A Madzima, Michael J Ormsbee, Erica A Schleicher, Robert J Moffatt, Lynn B Panton
INTRODUCTION: To evaluate 12 wk of resistance training (RT; n=16) and protein supplementation (RT+protein; n=17) on muscular strength, body composition and blood biomarkers of muscle (insulin-like growth factor-1 (IGF-1)), fat (adiponectin), and inflammation [human C-reactive protein (CRP)] in breast cancer survivors (BCS). METHODS: Thirty-three BCS (59±8yr) were measured pre and post training for one-repetition maximum (1-RM) muscular strength (chest press: leg extension); body composition (lean mass (LM); fat mass (FM)) via DXA and serum concentrations of IGF-1, adiponectin, and CRP...
March 1, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28244700/the-influence-of-protein-provision-in-the-early-phase-of-intensive-care-on-clinical-outcomes-for-critically-ill-patients-on-mechanical-ventilation
#15
Joo Han Song, Ho Sun Lee, Song Yee Kim, Eun Young Kim, Jie Ye Jung, Young Ae Kang, Moo Suk Park, Young Sam Kim, Se Kyu Kim, Joon Chang, Kyung Soo Chung
BACKGROUND AND OBJECTIVES: Mechanically ventilated patients often face progressive and rapid losses of body mass and muscle because of hypermetabolism and increased protein catabolism. To investigate the impact of adequate nutritional provision during the early phase of intensive care unit (ICU) admission on the clinical outcomes in patients with medical illnesses receiving mechanical ventilation support. METHODS AND STUDY DESIGN: Two hundred and eleven mechanically ventilated patients admitted to a 30-bed medical ICU were included...
March 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28241980/rehabilitation-and-nutritional-support-for-sarcopenic-dysphagia-and-tongue-atrophy-after-glossectomy-a-case-report
#16
Nao Hashida, Hiroshi Shamoto, Keisuke Maeda, Hidetaka Wakabayashi, Motoyuki Suzuki, Takashi Fujii
Swallowing dysfunction is related to long-term weight loss and reduced body mass index in patients with head and neck cancer. We describe a 76-y-old woman who had severe sarcopenic dysphagia and atrophy of the reconstructed tongue for 17 mo after subtotal glossectomy due to tongue cancer and lost 14 kg during that period. Upon admission, the patient received diagnoses of malnutrition in the context of social or environmental circumstances with insufficient energy intake, loss of muscle mass, localized fluid accumulation, weight loss, and sarcopenia due to reduced skeletal muscle mass (skeletal muscle index <3...
March 2017: Nutrition
https://www.readbyqxmd.com/read/28241978/high-prevalence-of-cachexia-in-newly-diagnosed-head-and-neck-cancer-patients-an-exploratory-study
#17
Harriët Jager-Wittenaar, Pieter U Dijkstra, Gerard Dijkstra, Johan Bijzet, Johannes A Langendijk, Bernard F A M van der Laan, Jan L N Roodenburg
OBJECTIVE: In patients with cancer, weight loss can be related to simple starvation, disturbed metabolism, or both. In patients with head and neck cancer (HNC), weight loss often is attributed to simple starvation because the obvious oral symptoms are known to hinder dietary intake. In this population, cachexia remains a relatively unexplored phenomenon. The aim of this study was to explore the prevalence of cachexia and precachexia in patients with newly diagnosed HNC. METHODS: Fifty-nine patients with newly diagnosed HNC were asked to participate in the prospective cohort study, from which only baseline data were used in the analyses...
March 2017: Nutrition
https://www.readbyqxmd.com/read/28228415/reduced-skeletal-muscle-fiber-size-following-caloric-restriction-is-associated-with-calpain-mediated-proteolysis-and-attenuation-of-igf-1-signaling
#18
Yue Lu, Jennifer S Bradley, Sarah R McCoski, John M Gonzalez, Alan D Ealy, Sally E Johnson
Caloric restriction decreases skeletal muscle mass in mammals, principally due to a reduction in fiber size. The effect of suboptimal nutrient intake on skeletal muscle metabolic properties in neonatal calves was examined. The longissimus muscle (LM) was collected after 8 wks consuming a control (CON) or caloric restricted (CR) diet and muscle fiber size, gene expression and metabolic signal transduction activity was measured. Results revealed that CR animals had smaller (P < 0.05) LM fiber cross-sectional area than CON, as expected...
February 22, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28224299/clinical-impact-of-sarcopenia-and-relevance-of-nutritional-intake-in-patients-before-and-after-allogeneic-hematopoietic-stem-cell-transplantation
#19
Shouichi Tanaka, Osamu Imataki, Atsuo Kitaoka, Shuji Fujioka, Etsuyo Hanabusa, Yumiko Ohbayashi, Makiko Uemura, Nobuo Arima, Tetsuji Yamamoto
PURPOSE: We conducted a retrospective study to evaluate the effect of rehabilitation on minimizing sarcopenia during hematopoietic stem cell transplantation (HSCT) therapy. METHODS: We developed a protocol to test for retention of physical function during HSCT. Muscle strength, muscle circumference, and muscle function before and after HSCT were measured. Consecutive patients with hematological malignancies who underwent HSCT treatment were recruited in this research...
February 21, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28219696/irisin-in-goldfish-carassius-auratus-effects-of-irisin-injections-on-feeding-behavior-and-expression-of-appetite-regulators-uncoupling-proteins-and-lipoprotein-lipase-and-fasting-induced-changes-in-fndc5-expression
#20
Zahndra Diann Butt, Jessica Dalton Hackett, Hélène Volkoff
Irisin is a peptide cleaved from the fibronectin type III domain containing protein 5 (FNDC5) gene that is secreted predominantly by muscle cells but also by other tissues including brain and intestine. In mammals, irisin has been shown to have thermogenic actions via the modulation of uncoupling proteins (UCPs) and to affect feeding and energy homeostasis via actions in brain, adipose tissue, liver, muscle and gastrointestinal tract. To examine the role of irisin on feeding and metabolism in fish, the effects of peripheral (intraperitoneal) injections of irisin on feeding behavior, glucose levels and the mRNA expressions of appetite regulators (cocaine and amphetamine regulated transcript CART, agouti related protein AgRP, orexin), UCPs and lipoprotein lipase LPL and brain factors (brain-derived neurotrophic factor , BDNF and tyrosine hydroxylase TH) were assessed in brain, white muscle and intestine...
February 20, 2017: Peptides
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