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Muscle nutrition exercise

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https://www.readbyqxmd.com/read/29232263/can-the-critically-ill-patient-generate-sufficient-energy-to-facilitate-exercise-in-the-icu
#1
Danielle E Bear, Selina M Parry, Zudin A Puthucheary
PURPOSE OF REVIEW: Trials of physical rehabilitation post critical illness have yet to deliver improved health-related quality of life in critical illness survivors. Muscle mass and strength are lost rapidly in critical illness and a proportion of patients continue to do so resulting in increased mortality and functional disability. Addressing this issue is therefore fundamental for recovery from critical illness. RECENT FINDINGS: Altered mitochondrial function occurs in the critically ill and is likely to result in decreased adenosine tri-phosphate (ATP) production...
December 9, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29226282/feasibility-of-conducting-a-6-month-long-home-based-exercise-program-with-protein-supplementation-in-elderly-community-dwelling-individuals-with-heart-failure
#2
Masil George, Gohar Azhar, Amanda Pangle, Eric Peeler, Amanda Dawson, Robert Coker, Kellie S Coleman, Amy Schrader, Jeanne Wei
Objective: Cardiac cachexia is a condition associated with heart failure, particularly in the elderly, and is characterized by loss of muscle mass with or without the loss of fat mass. Approximately 15% of elderly heart failure patients will eventually develop cardiac cachexia; such a diagnosis is closely associated with high morbidity and increased mortality. While the mechanism(s) involved in the progression of cardiac cachexia is incompletely established, certain factors appear to be contributory...
2017: Journal of Physiotherapy & Physical Rehabilitation
https://www.readbyqxmd.com/read/29225812/the-utility-of-whole-body-vibration-exercise-in-haemodialysis-patients-a-pilot-study
#3
Arthur Doyle, Karen Chalmers, David J Chinn, Fiona McNeill, Nicola Dall, Christopher H Grant
Background: Exercise improves physical capacity in patients with end-stage renal disease on haemodialysis (HD), but few patients engage in it. Whole-body vibration exercise (WBVE) is a novel protocol that has been shown to benefit frail elderly patients' rehabilitation. We assessed the utility of WBVE before HD sessions and tested methods to inform the design of a randomized controlled trial (RCT). Methods: Physical condition and quality of life were assessed at enrolment and repeated 2 weeks later in a pilot study of 49 patients undergoing regular HD...
December 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29203713/therapeutic-potential-of-heat-shock-protein-induction-for-muscular-dystrophy-and-other-muscle-wasting-conditions
#4
REVIEW
Savant S Thakur, Kristy Swiderski, James G Ryall, Gordon S Lynch
Duchenne muscular dystrophy is the most common and severe of the muscular dystrophies, a group of inherited myopathies caused by different genetic mutations leading to aberrant expression or complete absence of cytoskeletal proteins. Dystrophic muscles are prone to injury, and regenerate poorly after damage. Remorseless cycles of muscle fibre breakdown and incomplete repair lead to progressive and severe muscle wasting, weakness and premature death. Many other conditions are similarly characterized by muscle wasting, including sarcopenia, cancer cachexia, sepsis, denervation, burns, and chronic obstructive pulmonary disease...
January 19, 2018: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/29197960/sarcopenia-during-neoadjuvant-therapy-for-oesophageal-cancer-characterising-the-impact-on-muscle-strength-and-physical-performance
#5
Emer M Guinan, S L Doyle, A E Bennett, L O'Neill, J Gannon, J A Elliott, J O'Sullivan, J V Reynolds, J Hussey
PURPOSE: Preoperative chemo(radio)therapy for oesophageal cancer (OC) may have an attritional impact on body composition and functional status, impacting postoperative outcome. Physical decline with skeletal muscle loss has not been previously characterised in OC and may be amenable to physical rehabilitation. This study characterises skeletal muscle mass and physical performance from diagnosis to post-neoadjuvant therapy in patients undergoing preoperative chemo(radio)therapy for OC...
December 2, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29194762/cholinesterase-levels-predict-exercise-capacity-in-cardiac-recipients-early-after-transplantation
#6
Kazufumi Kitagaki, Michio Nakanishi, Rei Ono, Kazuya Yamamoto, Yuji Suzuki, Noriyuki Fukui, Hidetoshi Yanagi, Harumi Konishi, Masanobu Yanase, Norihide Fukushima
PURPOSE: Although cardiac rehabilitation is recommended for patients early after heart transplantation (HTx), adequate exercise effect cannot always be obtained, partly because in patients with chronic heart failure, exercise capacity is reduced due to malnutrition during waiting for HTx. This study aimed to investigate the relationships between exercise capacity and clinical variables, including nutritional indicators, early after HTx. PATIENTS AND METHODS: Forty three HTx recipients were studied...
December 1, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29189738/aging-gut-microbiota-at-the-cross-road-between-nutrition-physical-frailty-and-sarcopenia-is-there-a-gut-muscle-axis
#7
REVIEW
Andrea Ticinesi, Fulvio Lauretani, Christian Milani, Antonio Nouvenne, Claudio Tana, Daniele Del Rio, Marcello Maggio, Marco Ventura, Tiziana Meschi
Inadequate nutrition and physical inactivity are the mainstays of primary sarcopenia-physiopathology in older individuals. Gut microbiota composition is strongly dependent on both of these elements, and conversely, can also influence the host physiology by modulating systemic inflammation, anabolism, insulin sensitivity, and energy production. The bacterial metabolism of nutrients theoretically influences skeletal muscle cell functionality through producing mediators that drive all of these systemic effects...
November 30, 2017: Nutrients
https://www.readbyqxmd.com/read/29173121/fueling-for-performance
#8
Jeffrey R Bytomski
CONTEXT: Proper nutrition is crucial for an athlete to optimize his or her performance for training and competition. Athletes should be able to meet their dietary needs through eating a wide variety of whole food sources. EVIDENCE ACQUISITION: PubMed was searched for relevant articles published from 1980 to 2016. STUDY DESIGN: Clinical review. LEVEL OF EVIDENCE: Level 4. RESULTS: An athlete should have both daily and activity-specific goals for obtaining the fuel necessary for successful training...
November 1, 2017: Sports Health
https://www.readbyqxmd.com/read/29170984/clinical-nutrition-and-physical-rehabilitation-in-a-long-term-care-setting-preliminary-observations-in-sarcopenic-older-patients
#9
Sergio Dimori, Giorgio Leoni, Luca Fior, Fulvio Gasparotto
BACKGROUND: Sarcopenia could have a negative prognostic impact in long-term care residents, which are characterized by multiple comorbidities and a high level of dependence. However, there is limited evidence on its prevalence and management in this healthcare setting. METHODS: All residents living in a long-term care institution were screened for the presence of sarcopenia. Sarcopenic patients in whom functional status could be assessed were included, based on the Tinetti scale (TS) score, in two parallel single-arm trials and received a specific nutritional supplement for muscle mass recovery in combination (TS ≥ 10) or not (TS < 10) with a supervised physical exercise rehabilitation program for 12 months...
November 23, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29167745/the-use-of-smartphones-to-influence-lifestyle-changes-in-overweight-and-obese-youth-with-congenital-heart-disease-a-single-arm-study-pilot-and-feasibility-study-protocol-smart-heart-trial
#10
Meghan Rombeek, Stefanie De Jesus, Luis Altamirano-Diaz, Eva Welisch, Harry Prapavessis, Jamie A Seabrook, Kambiz Norozi
Background: Both obesity and congenital heart disease (CHD) are risk factors for the long-term cardiovascular health of children and adolescents. The addition of smart mobile technology to conventional lifestyle counseling for weight management offers great potential to appeal to technologically literate youth and can address a large geographical area with minimal burden to participants. This pilot study seeks to examine the influence of a 1-year lifestyle intervention on nutrition and physical activity-related health outcomes in overweight or obese children and adolescents with CHD...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29154428/muscle-wasting-and-sarcopenia-in-heart-failure-and-beyond-update-2017
#11
REVIEW
Jochen Springer, Joshua-I Springer, Stefan D Anker
Sarcopenia (loss of muscle mass and muscle function) is a strong predictor of frailty, disability and mortality in older persons and may also occur in obese subjects. The prevalence of sarcopenia is increased in patients suffering from chronic heart failure. However, there are currently few therapy options. The main intervention is resistance exercise, either alone or in combination with nutritional support, which seems to enhance the beneficial effects of training. Also, testosterone has been shown to increased muscle power and function; however, a possible limitation is the side effects of testosterone...
November 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29150719/preoperative-optimization-for-major-hepatic-resection
#12
REVIEW
Sarah Walcott-Sapp, Kevin G Billingsley
PURPOSE: Major hepatic resections are performed for primary hepatobiliary malignancies, metastatic disease, and benign lesions. Patients with chronic liver disease, including cirrhosis and steatosis, are at an elevated risk of malnutrition and impaired strength and exercise capacity, deficits which cause increased risk of postoperative complications and mortality. The aims of this report are to discuss the pathophysiology of changes in nutrition, exercise capacity, and muscle strength in patient populations likely to require major hepatectomy, and review recommendations for preoperative evaluation and optimization...
November 18, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29140739/cftr-genotype-and-maximal-exercise-capacity-in-cystic-fibrosis-a-cross-sectional-study
#13
Thomas Radtke, Helge Hebestreit, Sabina Gallati, Jane E Schneiderman, Julia Braun, Daniel Stevens, Erik Hj Hulzebos, Tim Takken, Steven R Boas, Don S Urquhart, Larry C Lands, Sergio Tejero, Aleksandar Sovtic, Tiffany Dwyer, Milos Petrovic, Ryan A Harris, Chantal Karila, Daniela Savi, Jakob Usemann, Meir Mei-Zahav, Elpis Hatziagorou, Felix Ratjen, Susi Kriemler
RATIONALE: Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in human skeletal muscle cells. Variations of CFTR dysfunction among patients with CF may present an important determinant of aerobic exercise capacity in CF. Previous studies on the relationship between CFTR genotype and aerobic exercise capacity are scarce and contradictory. OBJECTIVES: This study was designed to explore factors influencing aerobic exercise capacity, expressed as peak oxygen consumption (VO2peak) with a specific focus on CFTR genotype in children and adults with CF...
November 15, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29130720/-relationship-between-quality-of-life-physical-activity-nutrition-glycemic-control-and-sarcopenia-in-older-adults-with-type-2-diabetes-mellitus
#14
Cristina Casals-Vázquez, Ernesto Suárez-Cadenas, Francisca María Estébanez Carvajal, María Pilar Aguilar Trujillo, María M Jiménez Arcos, María Ángeles Vázquez Sáchez
INTRODUCTION: The term sarcopenia is defined as age-related loss of skeletal muscle mass and function, with a consequent impact on quality of life. However, there is a lack of studies examining the prevalence of sarcopenia in patients with type 2 diabetes mellitus (DM). OBJECTIVES: To analyze the prevalence of sarcopenia in patients over 65 years with type 2 DM and the influence of physical activity, diet, glycemic control, sex, age, and quality of life. METHODS: A total of 279 patients (155 females), aged 76...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29129214/exercise-and-older-adults
#15
REVIEW
Jorge Camilo Mora, Willy M Valencia
Regular exercise is essential for healthy aging and offers many health benefits, including reduced risk of all-cause mortality, chronic disease, and premature death. Because physical inactivity is prevalent, greater focus is needed on integrating exercise into care plans and counseling, and developing partnerships that support exercise opportunities. Older adults should be as physically active as their abilities and conditions allow. For substantial health benefits, older adults need to do aerobic, muscle-strengthening, and stretching exercises weekly, and balance activities as needed...
February 2018: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/29114510/effect-of-timing-of-whey-protein-supplement-on-muscle-damage-markers-after-eccentric-exercise
#16
Jooyoung Kim, Chulhyun Lee, Joohyung Lee
Whey protein is a nutritional supplement commonly ingested for recovery following exercise. However, the timing when whey protein supplement must be ingested after muscle-damaging exercise is debatable. Therefore, the present study investigated the effects of the timing of supplement ingestion on muscle damage markers after eccentric or muscle-damaging exercise. In total, 32 collegiate male students participated in this study; they were randomly assigned to control group (n=8), before supplement group (n=8), after supplement group (n=8), or before and after supplement group (n=8)...
August 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/29110174/murine-myoblast-migration-influence-of-replicative-ageing-and-nutrition
#17
Alexander D Brown, Graeme L Close, Adam P Sharples, Claire E Stewart
Cell migration is central to skeletal muscle repair following damage. Leucine and β-Hydroxy β-methylbutyric acid (HMB) are supplements consumed for recovery from muscle damaging exercise in humans, however, their impact on muscle cell migration with age is not yet understood. We hypothesised that replicatively aged ("aged"; P46-P48) myoblasts would be less efficient at basal and supplemented repair versus parental controls ("control"; P12-P16). Aged and control myoblasts were scratch-damaged and migration velocity, directionality and distance assessed over 48 h in the absence and presence of leucine (10 mM) or HMB (10 mM) ± PI3K/Akt (LY294002 10 μM), ERK (PD98059 5 μM) or mTOR (rapamycin 0...
November 7, 2017: Biogerontology
https://www.readbyqxmd.com/read/29097038/impact-of-the-calcium-form-of-%C3%AE-hydroxy-%C3%AE-methylbutyrate-upon-human-skeletal-muscle-protein-metabolism
#18
D J Wilkinson, T Hossain, M C Limb, B E Phillips, J Lund, J P Williams, M S Brook, J Cegielski, A Philp, S Ashcroft, J A Rathmacher, N J Szewczyk, K Smith, P J Atherton
BACKGROUND & AIMS: β-hydroxy-β-methylbutyrate (HMB) is purported as a key nutritional supplement for the preservation of muscle mass in health, disease and as an ergogenic aid in exercise. Of the two available forms of HMB (calcium (Ca-HMB) salt or free acid (FA-HMB)) - differences in plasma bioavailability have been reported. We previously reported that ∼3 g oral FA-HMB increased muscle protein synthesis (MPS) and reduced muscle protein breakdown (MPB). The objective of the present study was to quantify muscle protein metabolism responses to oral Ca-HMB...
October 6, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29083440/the-impact-of-dietary-protein-or-amino-acid-supplementation-on-muscle-mass-and-strength-in-elderly-people-individual-participant-data-and-meta-analysis-of-rct-s
#19
M Tieland, R Franssen, C Dullemeijer, C van Dronkelaar, H Kyung Kim, T Ispoglou, K Zhu, R L Prince, L J C van Loon, L C P G M de Groot
OBJECTIVES: Increasing protein or amino acid intake has been promoted as a promising strategy to increase muscle mass and strength in elderly people, however, long-term intervention studies show inconsistent findings. Therefore, we aim to determine the impact of protein or amino acid supplementation compared to placebo on muscle mass and strength in older adults by combining the results from published trials in a meta-analysis and pooled individual participant data analysis. DESIGN: We searched Medline and Cochrane databases and performed a meta-analysis on eight available trials on the effect of protein or amino acid supplementation on muscle mass and strength in older adults...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29076960/effects-of-combined-strength-and-endurance-training-on-physical-performance-and-biomarkers-of-healthy-young-women
#20
Heikki KyrÖlÄinen, Anthony C Hackney, Riikka Salminen, Johanna Repola, Keijo HÄkkinen, Jari Haimi
Cardiovascular fitness has decreased and obesity has increased in youth-adults world-wide during the last ten years. Therefore, there is an urgent need to find out optimal exercise training programs for improving physical performance and health outcomes, especially, among sedentary women. Subjects were 25-30-year-old females with very low physical activity, and 65 % of them were overweight (BMI >25). They performed endurance and strength training three times a week for nine weeks. Independent strength training and instructed endurance training by indoor cycling were prescribed...
October 20, 2017: Journal of Strength and Conditioning Research
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