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Muscle nutrition exercise

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https://www.readbyqxmd.com/read/28107410/prognostic-impact-of-ct-quantified-muscle-and-fat-distribution-before-and-after-first-line-chemotherapy-in-lung-cancer-patients
#1
Johanna Nattenmüller, Raoul Wochner, Thomas Muley, Martin Steins, Simone Hummler, Birgit Teucher, Joachim Wiskemann, Hans-Ulrich Kauczor, Mark Oliver Wielpütz, Claus Peter Heussel
INTRODUCTION: Cachexia and sarcopenia are associated with poor outcome and increased chemotherapy-induced toxicity in lung cancer patients. However, the complex interplay of obesity, sarcopenia and cachexia, and its impact on survival in the context of first-line-chemotherapy is not yet understood. METHODS: In 200 consecutively recruited lung cancer patients (70 female, mean age 62y; mean BMI 25 kg/m2; median follow-up 15.97 months) with routine staging-CT before and after chemotherapy (CTX, mean interval: 4...
2017: PloS One
https://www.readbyqxmd.com/read/28100512/postexercise-repletion-of-muscle-energy-stores-with-fructose-or-glucose-in-mixed-meals
#2
Robin Rosset, Virgile Lecoultre, Léonie Egli, Jérémy Cros, Ayse Sila Dokumaci, Karin Zwygart, Chris Boesch, Roland Kreis, Philippe Schneiter, Luc Tappy
BACKGROUND: Postexercise nutrition is paramount to the restoration of muscle energy stores by providing carbohydrate and fat as precursors of glycogen and intramyocellular lipid (IMCL) synthesis. Compared with glucose, fructose ingestion results in lower postprandial glucose and higher lactate and triglyceride concentrations. We hypothesized that these differences in substrate concentration would be associated with a different partition of energy stored as IMCLs or glycogen postexercise...
January 18, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28100190/translation-of-a-tailored-nutrition-and-resistance-exercise-intervention-for-elderly-people-to-a-real-life-setting-adaptation-process-and-pilot-study
#3
Ellen Ji van Dongen, Joanne N Leerlooijer, Jan M Steijns, Michael Tieland, Lisette Cpgm de Groot, Annemien Haveman-Nies
BACKGROUND: Combining increased dietary protein intake and resistance exercise training for elderly people is a promising strategy to prevent or counteract the loss of muscle mass and decrease the risk of disabilities. Using findings from controlled interventions in a real-life setting requires adaptations to the intervention and working procedures of healthcare professionals (HCPs). The aim of this study is to adapt an efficacious intervention for elderly people to a real-life setting (phase one) and test the feasibility and potential impact of this prototype intervention in practice in a pilot study (phase two)...
January 18, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28099900/skeletal-muscle-aging-influence-of-oxidative-stress-and-physical-exercise
#4
REVIEW
Mariana Janini Gomes, Paula Felippe Martinez, Luana Urbano Pagan, Ricardo Luiz Damatto, Marcelo Diacardia Mariano Cezar, Aline Regina Ruiz Lima, Katashi Okoshi, Marina Politi Okoshi
Skeletal muscle abnormalities are responsible for significant disability in the elderly. Sarcopenia is the main alteration occurring during senescence and a key public health issue as it predicts frailty, poor quality of life, and mortality. Several factors such as reduced physical activity, hormonal changes, insulin resistance, genetic susceptibility, appetite loss, and nutritional deficiencies are involved in the physiopathology of muscle changes. Sarcopenia is characterized by structural, biochemical, molecular and functional muscle changes...
January 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28066619/clinical-management-of-chronic-obstructive-pulmonary-disease-patients-with-muscle-dysfunction
#5
REVIEW
Joaquim Gea, Carme Casadevall, Sergi Pascual, Mauricio Orozco-Levi, Esther Barreiro
Muscle dysfunction is frequently observed in chronic obstructive pulmonary disease (COPD) patients, contributing to their exercise limitation and a worsening prognosis. The main factor leading to limb muscle dysfunction is deconditioning, whereas respiratory muscle dysfunction is mostly the result of pulmonary hyperinflation. However, both limb and respiratory muscles are also influenced by other negative factors, including smoking, systemic inflammation, nutritional abnormalities, exacerbations and some drugs...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28064172/effectiveness-of-an-intervention-to-prevent-frailty-in-pre-frail-community-dwelling-older-people-consulting-in-primary-care-a-randomised-controlled-trial
#6
M Serra-Prat, X Sist, R Domenich, L Jurado, A Saiz, A Roces, E Palomera, M Tarradelles, M Papiol
BACKGROUND: evidence on the effectiveness of interventions to prevent frailty is scarce. OBJECTIVE: to assess the effect of an intervention in preventing frailty progression in pre-frail older people. STUDY DESIGN: a randomised, open label, controlled trial with two parallel arms. POPULATION: community-dwelling pre-frail older people (≥70 years) consulting in primary care. INTERVENTION: nutritional assessment (and derivation to a Nutritional Unit for usual care in the event of nutritional risk) and a physical activity programme including aerobic exercise and a set of mixed strengthening, balance and coordination exercises CONTROL GROUP: patients receiving the usual care...
January 6, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28050921/influence-of-dietary-acid-load-on-exercise-performance
#7
Catherine Applegate, Mackenzie Mueller, Krystle E Zuniga
Diet composition can affect systemic pH and acid-base regulation, which may in turn influence exercise performance. An acidic environment in the muscle impairs performance and contributes to fatigue; therefore, current trends in sports nutrition place importance on maximizing the alkalinity of the body with ergogenic aids and dietary strategies. This review examines the evidence on the effects of dietary manipulations on acid load and exercise performance. Ten studies that investigated the effect of high versus low dietary acid loads on athletic performance generally identified that low dietary acid loads increased plasma pH, but did not consistently improve exercise performance at maximal or submaximal exercise intensities...
January 4, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28035017/muscle-damage-and-inflammation-during-recovery-from-exercise
#8
Jonathan M Peake, Oliver Neubauer, Paul A Della Gatta, Kazunori Nosaka
Unaccustomed exercise consisting of eccentric (i.e., lengthening) muscle contractions often results in muscle damage characterized by ultrastructural alterations in muscle tissue, clinical signs and symptoms (e.g., reduced muscle strength and range of motion, increased muscle soreness and swelling, efflux of myocellular proteins). The time course of recovery following exercise-induced muscle damage depends on the extent of initial muscle damage, which in turn is influenced by the intensity and duration of exercise, joint angle/muscle length and muscle groups used during exercise...
December 29, 2016: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28032232/effectiveness-of-a-preoperative-exercise-and-nutritional-support-program-for-elderly-sarcopenic-patients-with-gastric-cancer
#9
Kazuyoshi Yamamoto, Yukiko Nagatsuma, Yasunari Fukuda, Motohiro Hirao, Kazuhiro Nishikawa, Atsushi Miyamoto, Masataka Ikeda, Shoji Nakamori, Mitsugu Sekimoto, Kazumasa Fujitani, Toshimasa Tsujinaka
We established a preoperative exercise and nutritional support program for elderly sarcopenic patients with gastric cancer. Twenty-two gastric cancer patients aged 65 years or older with a diagnosis of sarcopenia according to the algorithm proposed by the European Working Group on Sarcopenia in Older People received our preoperative program. The median duration of the program participation was 16 days. Total calorie and protein intakes were significantly higher after the program than before [29.4 ± 6.9 kcal/kg ideal body weight (IBW) vs 27...
December 28, 2016: Gastric Cancer
https://www.readbyqxmd.com/read/28029078/nutrition-and-exercise-in-sarcopenia
#10
Stephen D Anton, Azumi Hida, Robert Mankowski, Andrew Layne, Lawrence Solberg, Arch G Mainous, Thomas W Buford
Sarcopenia is a debilitating condition that involves loss of muscle mass and function, which affects virtually everyone as they age, and can lead to frailty and ultimately disability. In growing recognition of the importance of both muscle strength and muscle mass relative to body size in contributing to functional decline, recent definitions have now incorporated grip strength and a correction for body mass as part of the key criteria that define sarcopenia. With this new definition, a much larger population of older adults are now at risk of sarcopenia...
December 27, 2016: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/28012805/clinical-implications-of-sarcopenia-on-decreased-bone-density-in-men-with-chronic-obstructive-pulmonary-disease
#11
Ji An Hwang, Young Sam Kim, Ah Young Leem, Moo Suk Park, Se Kyu Kim, Joon Chang, Ji Ye Jung
BACKGROUND: Sarcopenia and osteoporosis are systemic features of chronic obstructive pulmonary disease (COPD). The present study investigated the association between sarcopenia and osteopenia/osteoporosis, and the factors associated with low bone mineral density (BMD) in men with COPD. METHODS: Data of 777 men with COPD who underwent both pulmonary function test and dual energy X-ray absorptiometry were extracted from the Korean National Health and Nutritional Examination Survey database between 2008 and 2011...
December 21, 2016: Chest
https://www.readbyqxmd.com/read/27973615/soluble-milk-protein-supplementation-with-moderate-physical-activity-improves-locomotion-function-in-aging-rats
#12
Aude Lafoux, Charlotte Baudry, Cécile Bonhomme, Pascale Le Ruyet, Corinne Huchet
Aging is associated with a loss of muscle mass and functional capacity. Present study was designed to compare the impact of specific dairy proteins on muscular function with or without a low-intensity physical activity program on a treadmill in an aged rat model. We investigated the effects of nutritional supplementation, five days a week over a 2-month period with a slow digestible protein, casein or fast digestible proteins, whey or soluble milk protein, on strength and locomotor parameters in sedentary or active aged Wistar RjHan rats (17-19 months of age)...
2016: PloS One
https://www.readbyqxmd.com/read/27964962/improving-community-ambulation-after-hip-fracture-protocol-for-a-randomised-controlled-trial
#13
D Orwig, K K Mangione, M Baumgarten, M Terrin, R Fortinsky, A M Kenny, A L Gruber-Baldini, B Beamer, Ana Tosteson, M Shardell, L Magder, E Binder, K Koval, B Resnick, R L Craik, J Magaziner
INTRODUCTION: After a hip fracture in older persons, significant disability often remains; dependency in functional activities commonly persists beyond 3 months after surgery. Endurance, dynamic balance, quadriceps strength, and function are compromised, and contribute to an inability to walk independently in the community. In the United States, people aged 65 years and older are eligible to receive Medicare funding for physiotherapy for a limited time after a hip fracture. A goal of outpatient physiotherapy is independent and safe household ambulation 2 to 3 months after surgery...
January 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/27956218/an-intensive-lifestyle-intervention-reduces-circulating-oxidised-low-density-lipoprotein-and-increases-human-paraoxonase-activity-in-obese-subjects
#14
Angelo Russo, Irene Pirisinu, Carmine Vacca, Elisa Reginato, Emilia Sbroma Tomaro, Roberto Pippi, Cristina Aiello, Vincenzo Nicola Talesa, Pierpaolo De Feo, Rita Romani
OBJECTIVE: Obesity has a great impact on cardiovascular morbidity and mortality, the treatment of this pathological state is important given the significant health consequences. Lifestyle and behaviour changes play a significant role in weight management. The purpose of this study was to investigate the impact of an intensive multidisciplinary lifestyle intervention on well-known atherogenic factors in a group of overweight and obese subjects. METHODS: A total of 44 people with overweight/obesity underwent a lifestyle intervention based on nutritional education, psychological support and a 3-month exercise training program with a frequency of twice a week...
December 9, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27923983/sex-differences-in-function-and-structure-of-the-quadriceps-muscle-in-chronic-obstructive-pulmonary-disease-patients
#15
Pilar Ausín, Juana Martínez-Llorens, Marina Sabaté-Bresco, Carme Casadevall, Esther Barreiro, Joaquim Gea
Chronic obstructive pulmonary disease (COPD) is a complex disorder with extrapulmonary manifestations. Even though there is some knowledge regarding sex differences in the lung disease, little is known about extrapulmonary manifestations. Our aim was to analyze the specific profile of muscle dysfunction, structure, and biology in COPD women. Twenty-one women and 19 men with stable COPD as well as 15 controls were included. Nutritional status, physical activity, lung and muscle function, exercise capacity, and quality of life were assessed...
December 6, 2016: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/27923981/sarcopenia-and-frailty-in-chronic-respiratory-disease-lessons-from-gerontology
#16
Anna E Bone, Nilay Hepgul, Samantha Kon, Matthew Maddocks
Sarcopenia and frailty are geriatric syndromes characterized by multisystem decline, which are related to and reflected by markers of skeletal muscle dysfunction. In older people, sarcopenia and frailty have been used for risk stratification, to predict adverse outcomes and to prompt intervention aimed at preventing decline in those at greatest risk. In this review, we examine sarcopenia and frailty in the context of chronic respiratory disease, providing an overview of the common assessments tools and studies to date in the field...
December 6, 2016: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/27923448/fit-with-good-fat-the-role-of-n-3-polyunsaturated-fatty-acids-on-exercise-performance
#17
REVIEW
Mariasole Da Boit, Angus M Hunter, Stuart R Gray
N-3 PUFA (n-3) polyunsaturated fatty acids (PUFA) are a family of fatty acids mainly found in oily fish and fish oil supplements. The effects of n-3 PUFA on health are mainly derived from its anti-inflammatory proprieties and its influence on immune function. Lately an increased interest in n-3 PUFA supplementation has reached the world of sport nutrition, where the majority of athletes rely on nutrition strategies to improve their training and performance. A vast amount of attention is paid in increasing metabolic capacity, delaying the onset of fatigue, and improving muscle hypertrophy and neuromuscular function...
January 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/27922941/exercise-training-ameliorates-glucosamine-induced-insulin-resistance-in-ovariectomized-rats
#18
Chung-Hwan Chen, Tsang-Hai Huang, Tsung-Lin Cheng, Chi-Fen Chang, Chau-Zen Wang, Meng-Hsing Wu, Lin Kang
OBJECTIVE: Glucosamine (GlcN), which has been reported to induce insulin resistance (IR), is a popular nutritional supplement used to treat osteoarthritis in menopausal women. We previously demonstrated that GlcN treatment caused IR in ovariectomized rats by reducing the expression of glucose transport protein subtype 4 (GLUT-4) in skeletal muscle. In the present study, we hypothesized that endurance exercise training can reverse GlcN-induced IR. METHODS: Fifty female rats were randomly divided into five groups with 10 rats in each group: (1) sham-operated group; (2) sham-operated group with GlcN treatment for 14 days; (3) ovariectomy (OVX) group; (4) OVX with GlcN treatment; and (5) OVX with GlcN treatment followed by exercise training (running program) for 8 weeks...
December 5, 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27922496/metabolic-myopathies
#19
Mark A Tarnopolsky
PURPOSE OF REVIEW: Metabolic myopathies are genetic disorders that impair intermediary metabolism in skeletal muscle. Impairments in glycolysis/glycogenolysis (glycogen-storage disease), fatty acid transport and oxidation (fatty acid oxidation defects), and the mitochondrial respiratory chain (mitochondrial myopathies) represent the majority of known defects. The purpose of this review is to develop a diagnostic and treatment algorithm for the metabolic myopathies. RECENT FINDINGS: The metabolic myopathies can present in the neonatal and infant period as part of more systemic involvement with hypotonia, hypoglycemia, and encephalopathy; however, most cases present in childhood or in adulthood with exercise intolerance (often with rhabdomyolysis) and weakness...
December 2016: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/27901247/anabolic-steroids-for-rehabilitation-after-hip-fracture-in-older-people
#20
Vaqas Farooqi, Maayken E L van den Berg, Ian D Cameron, Maria Crotty
BACKGROUND: Hip fracture occurs predominantly in older people, many of whom are frail and undernourished. After hip fracture surgery and rehabilitation, most patients experience a decline in mobility and function. Anabolic steroids, the synthetic derivatives of the male hormone testosterone, have been used in combination with exercise to improve muscle mass and strength in athletes. They may have similar effects in older people who are recovering from hip fracture. OBJECTIVES: To examine the effects (primarily in terms of functional outcome and adverse events) of anabolic steroids after surgical treatment of hip fracture in older people...
September 2016: São Paulo Medical Journal, Revista Paulista de Medicina
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