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Muscle nutrition

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https://www.readbyqxmd.com/read/28723982/assessment-of-nutritional-status-of-children-and-adolescents-with-spastic-quadriplegic-cerebral-palsy
#1
Thaisa Barboza Caselli, Elizete Aparecida Lomazi, Maria Augusta Santos Montenegro, Maria Angela Bellomo-Brandão
BACKGROUND: Due to several factors, such as gastrointestinal's diseases and difficulty in feeding, children with Spastic Quadriplegic Cerebral Palsy tend to present nutritional deficits. OBJECTIVE: To assess the nutritional status of pediatric patients with Spastic Quadriplegic Cerebral Palsy according to reference curves for this population and with the measures of folds and circumferences, obtained by the upper arm circumference and triceps skin fold. METHODS: The data were obtained from: knee-height, estimated height, weight, upper arm circumference, and triceps skin fold...
July 6, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28721834/the-interaction-between-nutrition-and-exercise-for-promoting-health-and-performance
#2
Oliver C Witard, Derek Ball
The theme of The Nutrition Society Spring Conference 2017 was on the interaction between nutrition and exercise for promoting healthy ageing, maintaining cognitive function and improving the metabolic health of the population. The importance of this theme is highlighted by the public health issues surrounding obesity, diabetes and the age-related loss of skeletal muscle mass (sarcopenia). The opening symposium provided a historical perspective of both invasive and non-invasive methodologies for measuring exercise energetics and energy balance...
July 19, 2017: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/28721555/the-value-of-physical-performance-measurements-alongside-assessment-of-sarcopenia-in-predicting-receipt-and-completion-of-planned-treatment-in-non-small-cell-lung-cancer-an-observational-exploratory-study
#3
Jemima T Collins, Simon Noble, John Chester, Helen E Davies, William D Evans, Daniel Farewell, Jason F Lester, Diane Parry, Rebecca Pettit, Anthony Byrne
INTRODUCTION: The presence of muscle mass depletion is associated with poor outcomes and survival in cancer. Alongside muscle mass, assessment of muscle strength or physical performance is essential for the diagnosis of sarcopenia. Non-small cell lung cancer (NSCLC) is a prevalent form of cancer with high mortality, and Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) is commonly used to assess patients' suitability for treatment. However, a significant proportion of patients with good PS are unable to complete multidisciplinary team (MDT)-planned treatment...
July 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28721434/muscle-measures-and-nutritional-status-at-hospital-admission-predict-survival-and-independent-living-of-older-patients-the-empower-study
#4
S Verlaan, J M Van Ancum, V D Pierik, J P Svan Wijngaarden, K Scheerman, C G M Meskers, A B Maier
OBJECTIVES: Older adults with sarcopenia and malnutrition are at risk for co-morbidities, hospitalization, institutionalization, and mortality. In case of hospitalization, risks may be further increased, especially in case of suboptimal dietary intake. The aim of our study was to assess whether muscle mass, muscle strength, functional performance, and nutritional status at hospital admission were associated with survival and independent living among older patients three months after discharge...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28719669/a-whey-protein-based-multi-ingredient-nutritional-supplement-stimulates-gains-in-lean-body-mass-and-strength-in-healthy-older-men-a-randomized-controlled-trial
#5
Kirsten E Bell, Tim Snijders, Michael Zulyniak, Dinesh Kumbhare, Gianni Parise, Adrian Chabowski, Stuart M Phillips
Protein and other compounds can exert anabolic effects on skeletal muscle, particularly in conjunction with exercise. The objective of this study was to evaluate the efficacy of twice daily consumption of a protein-based, multi-ingredient nutritional supplement to increase strength and lean mass independent of, and in combination with, exercise in healthy older men. Forty-nine healthy older men (age: 73 ± 1 years [mean ± SEM]; BMI: 28.5 ± 1.5 kg/m2) were randomly allocated to 20 weeks of twice daily consumption of either a nutritional supplement (SUPP; n = 25; 30 g whey protein, 2...
2017: PloS One
https://www.readbyqxmd.com/read/28717810/association-between-adiposity-and-disability-in-the-lc65-cohort
#6
N Danon-Hersch, S Fustinoni, P Bovet, J Spagnoli, B Santos-Eggimann
OBJECTIVES: To examine the longitudinal association between body mass index (BMI) and waist circumference (WC) with mortality and incident disability in Lc65+ cohort. DESIGN: Population-based cohort of non-institutionalized adults with up to 8.9 years of follow-up. SETTING: City of Lausanne, Switzerland. PARTICIPANTS: 1,293 individuals aged 65 to 70 at baseline (58% women). MEASUREMENTS: BMI, WC and covariates were measured at baseline in 2004-2005...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28712119/circulating-activin-a-predicts-survival-in-cancer-patients
#7
Audrey Loumaye, Marie de Barsy, Maxime Nachit, Pascale Lause, Aline van Maanen, Pierre Trefois, Damien Gruson, Jean-Paul Thissen
BACKGROUND: Several experimental evidences pinpoint the possible role of Activin A (ActA) as a driver of cancer cachexia. Supporting this hypothesis, we showed recently that human cancer cachexia is associated with high ActA levels. Moreover, ActA levels were correlated with body weight loss and skeletal muscle density, two prognostic factors in cancer patients. Our goal was therefore to investigate the value of ActA to predict survival in cancer patients. METHODS: Patients with colorectal or lung cancer were prospectively enrolled at the time of diagnosis or relapse between January 2012 and March 2014...
July 15, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28706091/predict-cp-study-protocol-of-implementation-of-comprehensive-surveillance-to-predict-outcomes-for-school-aged-children-with-cerebral-palsy
#8
Roslyn N Boyd, Peter Sw Davies, Jenny Ziviani, Stewart Trost, Lee Barber, Robert Ware, Stephen Rose, Koa Whittingham, Leanne Sakzewski, Kristie Bell, Christopher Carty, Steven Obst, Katherine Benfer, Sarah Reedman, Priya Edwards, Megan Kentish, Lisa Copeland, Kelly Weir, Camilla Davenport, Denise Brooks, Alan Coulthard, Rebecca Pelekanos, Andrea Guzzetta, Simona Fiori, Meredith Wynter, Christine Finn, Andrea Burgess, Kym Morris, John Walsh, Owen Lloyd, Jennifer A Whitty, Paul A Scuffham
OBJECTIVES: Cerebral palsy (CP) remains the world's most common childhood physical disability with total annual costs of care and lost well-being of $A3.87b. The PREDICT-CP (NHMRC 1077257 Partnership Project: Comprehensive surveillance to PREDICT outcomes for school age children with CP) study will investigate the influence of brain structure, body composition, dietary intake, oropharyngeal function, habitual physical activity, musculoskeletal development (hip status, bone health) and muscle performance on motor attainment, cognition, executive function, communication, participation, quality of life and related health resource use costs...
July 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28702900/selected-in-season-nutritional-strategies-to-enhance-recovery-for-team-sport-athletes-a-practical-overview
#9
REVIEW
Lisa E Heaton, Jon K Davis, Eric S Rawson, Ryan P Nuccio, Oliver C Witard, Kimberly W Stein, Keith Baar, James M Carter, Lindsay B Baker
Team sport athletes face a variety of nutritional challenges related to recovery during the competitive season. The purpose of this article is to review nutrition strategies related to muscle regeneration, glycogen restoration, fatigue, physical and immune health, and preparation for subsequent training bouts and competitions. Given the limited opportunities to recover between training bouts and games throughout the competitive season, athletes must be deliberate in their recovery strategy. Foundational components of recovery related to protein, carbohydrates, and fluid have been extensively reviewed and accepted...
July 12, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28702872/dietary-supplementation-of-selenium-enriched-probiotics-enhances-meat-quality-of-broiler-chickens-gallus-gallus-domesticus-raised-under-high-ambient-temperature
#10
Alam Zeb Khan, Shahnawaz Kumbhar, Yunhuan Liu, Mohammad Hamid, Cuiling Pan, Sonia Agostinho Nido, Fahmida Parveen, Kehe Huang
We investigated the effects of selenium-enriched probiotics (SP) on broiler meat quality under high ambient temperature and explore their underlying mechanisms. A total of 200 1-day-old male broiler chicks (Ross 308) were randomly allotted to four treatment groups, each with five replicates, in groups of ten birds. These birds were fed a corn-soybean basal diet (C), a basal diet plus probiotics supplementation (P), a basal diet plus Se supplementation in the form of sodium selenite (SS, 0.30 mg Se/kg), and a basal diet with the addition of selenium-enriched probiotics (SP, 0...
July 12, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28702319/grandpaternal-induced-transgenerational-dietary-reprogramming-of-the-unfolded-protein-response-in-skeletal-muscle
#11
Petter S Alm, Thais de Castro Barbosa, Romain Barrès, Anna Krook, Juleen R Zierath
OBJECTIVE: Parental nutrition and lifestyle impact the metabolic phenotype of the offspring. We have reported that grandpaternal chronic high-fat diet (HFD) transgenerationally impairs glucose metabolism in subsequent generations. Here we determined whether grandpaternal diet transgenerationally impacts the transcriptome and lipidome in skeletal muscle. Our aim was to identify tissue-specific pathways involved in transgenerational inheritance of environmental-induced phenotypes. METHODS: F0 male Sprague-Dawley rats were fed a HFD or chow for 12 weeks before breeding with chow-fed females to generate the F1 generation...
July 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/28697184/insulin-action-and-resistance-in-obesity-and-type-2-diabetes
#12
Michael P Czech
Nutritional excess is a major forerunner of type 2 diabetes. It enhances the secretion of insulin, but attenuates insulin's metabolic actions in the liver, skeletal muscle and adipose tissue. However, conflicting evidence indicates a lack of knowledge of the timing of these events during the development of obesity and diabetes, pointing to a key gap in our understanding of metabolic disease. This Perspective reviews alternate viewpoints and recent results on the temporal and mechanistic connections between hyperinsulinemia, obesity and insulin resistance...
July 11, 2017: Nature Medicine
https://www.readbyqxmd.com/read/28696961/current-body-composition-measurement-techniques
#13
Thaisa Lemos, Dympna Gallagher
PURPOSE OF REVIEW: The current article reviews the most innovative and precise, available methods for quantification of in-vivo human body composition. RECENT FINDINGS: Body composition measurement methods are continuously being perfected. Ongoing efforts involve multisegmental and multifrequency bioelectrical impedance analysis, quantitative magnetic resonance for total body water, fat, and lean tissue measurements, imaging to further define ectopic fat depots...
July 10, 2017: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/28690550/targeting-inflammation-and-downstream-protein-metabolism-in-sarcopenia-a-brief-up-dated-description-of-concurrent-exercise-and-leucine-based-multimodal-intervention
#14
REVIEW
Zhi Xia, Jason Cholewa, Yan Zhao, Hua-Yu Shang, Yue-Qin Yang, Kassiana Araújo Pessôa, Quan-Sheng Su, Fernanda Lima-Soares, Nelo Eidy Zanchi
Sarcopenia is defined as the progressive loss of muscle mass with age, and poses a serious threat to the physiological and psychological health of the elderly population with consequential economic and social burdens. Chronic low-grade inflammation plays a central role in the development of sarcopenia such that it alters cellular protein metabolism to favor proteolysis over synthesis, and thereby accelerates muscular atrophy. The purpose of this review is to highlight how exercise and nutrition intervention strategies can attenuate or treat sarcopenia...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28689564/sarcopenia
#15
REVIEW
Jean Woo
Sarcopenia refers to age-related muscle loss, defined using a combination of appendicular muscle mass, muscle strength, and physical performance measures. The pathogenesis depends on a balance between positive and negative regulators of muscle growth. Sarcopenia increases the risk for falls, fractures, dependency, use of hospital services, institutionalization, poor quality of life, and mortality. In clinical practice, brief screening tools, such as the 5-item SARC-F score, may be useful. Although pharmacologic treatments are actively being studied, the current mainstay consists of optimizing nutrition status, in particular protein and vitamin D status, and resistance exercises...
August 2017: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/28687307/altered-neurobiological-function-of-brainstem-hypoglossal-neurons-in-digeorge-22q11-2-deletion-syndrome
#16
Xin Wang, Corey Bryan, Anthony-Samuel LaMantia, David Mendelowitz
DiGeorge/22q11.2 Deletion Syndrome (22q11DS) is a common genetic microdeletion syndrome that underlies several neurodevelopmental disorders including autism, attention deficit/hyperactivity disorder, and schizophrenia. In addition to cognitive impairments, those with 22q11DS have disrupted feeding and swallowing from birth onward. This perinatal dysphagia significantly compromises nutritional status, impairs appropriate weight gain, and can lead to life threatening aspiration-based infections. Appropriately timed excitation and inhibition of brainstem hypoglossal motor neurons, which innervate tongue muscles, is essential for proper feeding and swallowing...
July 4, 2017: Neuroscience
https://www.readbyqxmd.com/read/28685860/exercise-mediated-modulation-of-autophagy-in-skeletal-muscle
#17
REVIEW
Marcos Martin-Rincon, David Morales-Alamo, Jose A L Calbet
Although exercise exerts multiple beneficial health effects, it may also damage cellular structures. Damaged elements are continuously degraded and its constituents recycled to produce renovated structures through a process called autophagy, which is essential for the adaptation to training. Autophagy is particularly active in skeletal muscle, where it can be evaluated by using specific molecular markers of activation (unc-51-like kinase 1 (ULK1) phosphorylation) and specific proteins indicating increased autophagosome content (increased total LC3, LC3-II, LC3-II/LC3-I ratio)...
July 7, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28684736/fish-oil-enriched-nutrition-combined-with-systemic-chemotherapy-for-gastrointestinal-cancer-patients-with-cancer-cachexia
#18
Yumiko Shirai, Yoshinaga Okugawa, Asahi Hishida, Aki Ogawa, Kyoko Okamoto, Miki Shintani, Yuki Morimoto, Ryutaro Nishikawa, Takeshi Yokoe, Koji Tanaka, Hisashi Urata, Yuji Toiyama, Yasuhiro Inoue, Motoyoshi Tanaka, Yasuhiko Mohri, Ajay Goel, Masato Kusunoki, Donald C McMillan, Chikao Miki
Despite recent advances in chemotherapy for gastrointestinal cancer, a crucial factor related to poor prognosis is reduced tolerance to chemotherapy induced by cancer cachexia. Fish oil (FO)-derived eicosapentaenoic acid (EPA) modulates inflammation in patients with various malignancies; however, the impact of FO-enriched nutrition as a combined modality therapy on clinical outcomes remains controversial. We systemically analysed chronological changes in biochemical and physiological status using bioelectrical impedance analysis in 128 gastrointestinal cancer patients provided with or without FO-enriched nutrition during chemotherapy...
July 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28683706/sarcopenia-what-should-a-pharmacist-know
#19
Alfonso J Cruz-Jentoft
Sarcopenia (or muscle insufficiency) is a geriatric syndrome characterized by a progressive and generalized loss of skeletal muscle mass and function which has adverse consequences, particularly physical disability, falls and death. It can develop slowly, as a chronic condition that emerges over many years, or acutely, generally due to immobilization associated with an acute disease. The physiopathology of sarcopenia is complex, and affects both the muscle and its neurological and hormonal regulation...
July 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28679946/independent-tissue-contributors-to-obesity-associated-insulin-resistance
#20
Yvo Ham Kusters, Casper G Schalkwijk, Alfons Jhm Houben, M Eline Kooi, Lucas Lindeboom, Jos Op 't Roodt, Peter J Joris, Jogchum Plat, Ronald P Mensink, Eugene J Barrett, Coen DA Stehouwer
BACKGROUND: Induction of insulin resistance is a key pathway through which obesity increases risk of type 2 diabetes, hypertension, dyslipidemia, and cardiovascular events. Although the detrimental effects of obesity on insulin sensitivity are incompletely understood, accumulation of visceral, subcutaneous, and liver fat and impairment of insulin-induced muscle microvascular recruitment (MVR) may be involved. As these phenotypic changes often coincide in obesity, we aimed to unravel whether they independently contribute to insulin resistance and thus constitute separate targets for intervention...
July 6, 2017: JCI Insight
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