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https://www.readbyqxmd.com/read/29334260/crude-extract-of-origanum-vulgare-l-induced-cell-death-and-suppressed-mapk-and-pi3-akt-signaling-pathways-in-sw13-and-h295r-cell-lines
#1
Beatrice Rubin, Jacopo Mansi, Halenya Monticelli, Loris Bertazza, Marco Redaelli, Francesca Sensi, Maira Zorzan, Carla Scaroni, Caterina Mian, Maurizio Iacobone, Decio Armanini, Cristina Bertolini, Susi Barollo, Marco Boscaro, Raffaele Pezzani
Oregano (Origanum vulgare L.) is a common aromatic plant used in Mediterranean and Asian Regions for treating respiratory diseases, painful menstruation, rheumatoid arthritis, etc. Recently its role as an anticancer plant has been suggested, although oregano has been never evaluated into adrenocortical tumour cell models. This study analysed for the first time the anticancer effects of a crude extract of wild mountain oregano (Origanum vulgare L.) in SW13 and H295R cell lines. The crude extract was characterised by GC/MS and the toxic effects of oregano were first analysed by brine shrimp lethality assay...
January 15, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29331835/integrating-priority-areas-and-ecological-corridors-into-national-network-for-conservation-planning-in-china
#2
Jie Liang, Xinyue He, Guangming Zeng, Minzhou Zhong, Xiang Gao, Xin Li, Xiaodong Li, Haipeng Wu, Chunting Feng, Wenle Xing, Yilong Fang, Dan Mo
Considering that urban expansion and increase of human activities represent important threats to biodiversity and ecological processes in short and long term, developing protected area (PA) network with high connectivity is considered as a valuable conservation strategy. However, conservation planning associated with the large-scale network in China involves important information loopholes about the land cover and landscape connectivity. In this paper, we made an integrative analysis for the identification of conservation priority areas and least-cost ecological corridors (ECs) in order to promote a more representative, connected and efficient ecological PA network for this country...
January 11, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29331295/helicopter-mountain-rescue-in-slovenia-from-2011-to-2015
#3
Janina Golob Deeb, Nicholas Walter, Caroline Carrico, Miha Gašperin, George R Deeb
INTRODUCTION: The popularity of adventure recreation in wilderness areas across the world continues to increase. Nevertheless, the risk of injury and illness remains significant. The purpose of this study is to analyze the mountain rescue operations performed in Slovenia between 2011 and 2015. METHODS: This retrospective study reports mountain rescue operations documented by the Slovenian National Mountain Rescue Association. The annual number of ground-based and helicopter-based rescues were identified and compared...
January 10, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/29330574/ectomycorrhizal-fungal-communities-in-alpine-relict-forests-of-pinus-pumila-on-mt-norikura-japan
#4
Takahiko Koizumi, Masahira Hattori, Kazuhide Nara
Ectomycorrhizal (ECM) symbioses are indispensable for the establishment of host trees, yet available information of ECM symbiosis in alpine forests is scarce. Pinus pumila is a typical ice age relict tree species in Japan and often forms monodominant dwarf vegetation above the tree line in mountains. We studied ECM fungi colonizing P. pumila on Mt. Norikura, Japan, with reference to host developmental stages, i.e., from current-year seedlings to mature trees. ECM fungal species were identified based on rDNA ITS sequences...
January 12, 2018: Mycorrhiza
https://www.readbyqxmd.com/read/29330526/relationship-among-land-surface-temperature-and-lucc-ndvi-in-typical-karst-area
#5
Yuanhong Deng, Shijie Wang, Xiaoyong Bai, Yichao Tian, Luhua Wu, Jianyong Xiao, Fei Chen, Qinghuan Qian
Land surface temperature (LST) can reflect the land surface water-heat exchange process comprehensively, which is considerably significant to the study of environmental change. However, research about LST in karst mountain areas with complex topography is scarce. Therefore, we retrieved the LST in a karst mountain area from Landsat 8 data and explored its relationships with LUCC and NDVI. The results showed that LST of the study area was noticeably affected by altitude and underlying surface type. In summer, abnormal high-temperature zones were observed in the study area, perhaps due to karst rocky desertification...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29330378/mechanisms-controlling-the-impact-of-multi-year-drought-on-mountain-hydrology
#6
Roger C Bales, Michael L Goulden, Carolyn T Hunsaker, Martha H Conklin, Peter C Hartsough, Anthony T O'Geen, Jan W Hopmans, Mohammad Safeeq
Mountain runoff ultimately reflects the difference between precipitation (P) and evapotranspiration (ET), as modulated by biogeophysical mechanisms that intensify or alleviate drought impacts. These modulating mechanisms are seldom measured and not fully understood. The impact of the warm 2012-15 California drought on the heavily instrumented Kings River basin provides an extraordinary opportunity to enumerate four mechanisms that controlled the impact of drought on mountain hydrology. Two mechanisms intensified the impact: (i) evaporative processes have first access to local precipitation, which decreased the fractional allocation of P to runoff in 2012-15 and reduced P-ET by 30% relative to previous years, and (ii) 2012-15 was 1 °C warmer than the previous decade, which increased ET relative to previous years and reduced P-ET by 5%...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29330330/greening-up-the-mountain
#7
V Vandvik, A H Halbritter, R J Telford
No abstract text is available yet for this article.
January 12, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29329457/a-novel-application-of-rnase-h2-dependent-quantitative-pcr-for-detection-and-quantification-of-grosmannia-clavigera-a-mountain-pine-beetle-fungal-symbiont-in-environmental-samples
#8
Chandra H McAllister, Colleen E Fortier, Kate R St Onge, Bianca M Sacchi, Meaghan J Nawrot, Troy Locke, Janice E K Cooke
Mountain pine beetle (Dendroctonus ponderosae Hopkins; MPB) is an economically and ecologically important pest of pine species in western North America. Mountain pine beetles form complex multipartite relationships with microbial partners, including the ophiostomoid fungi Grosmannia clavigera (Robinson-Jeffrey and Davidson) Zipfel, de Beer and Wingfield, Ophiostoma montium (Rumbold) von Arx, Grosmannia aurea (Robinson-Jeffrey and Davidson) Zipfel, de Beer and Wingfield, Leptographium longiclavatum (Lee, Kim, and Breuil) and Leptographium terebrantis (Barras and Perry)...
January 10, 2018: Tree Physiology
https://www.readbyqxmd.com/read/29329302/phylogeography-and-conservation-genetics-of-the-rare-and-relict-bretschneidera-sinensis-akaniaceae
#9
Mei-Na Wang, Lei Duan, Qi Qiao, Zheng-Feng Wang, Elizabeth A Zimmer, Zhong-Chao Li, Hong-Feng Chen
Bretschneidera sinensis, a class-I protected wild plant in China, is a relic of the ancient Tertiary tropical flora endemic to Asia. However, little is known about its genetics and phylogeography. To elucidate the current phylogeographic patterns and infer the historical population dynamics of B. sinensis, and to make recommendations for its conservation, three non-coding regions of chloroplast DNA (trnQ-rps16, rps8-rps11, and trnT-trnL) were amplified and sequenced across 256 individuals from 23 populations of B...
2018: PloS One
https://www.readbyqxmd.com/read/29328481/ttf1%C3%A2-np-induces-protective-autophagy-during-apoptosis-by-inhibiting-the-akt-mtor-pathway-and-activating-jnk-in-human-liver-cancer-cells
#10
Xuan Zhang, Meilan Zhang, Bin Xiao, Wenjun Jiao, Silin Zhang, Xuewu Zhang
TTF1‑NP is a flavonoid nanoparticle based on 5,2',4'‑trihydroxy‑6,7,5'‑trimethoxyflavone (TTF1), which is derived from the medicinal plant Sorbaria sorbifolia that grows in the Changbai Mountain. We previously demonstrated antitumor effects of TTF1‑NP in human hepatoma including induction of apoptosis and inhibition of angiogenesis, migration and invasion. Herein, we examined the effects of TTF1‑NP on autophagy and its relationship with apoptosis, and explored potential underlying mechanisms in human hepatoma cell lines...
January 5, 2018: Oncology Reports
https://www.readbyqxmd.com/read/29326978/seismic-signature-of-active-intrusions-in-mountain-chains
#11
Francesca Di Luccio, Giovanni Chiodini, Stefano Caliro, Carlo Cardellini, Vincenzo Convertito, Nicola Alessandro Pino, Cristiano Tolomei, Guido Ventura
Intrusions are a ubiquitous component of mountain chains and testify to the emplacement of magma at depth. Understanding the emplacement and growth mechanisms of intrusions, such as diapiric or dike-like ascent, is critical to constrain the evolution and structure of the crust. Petrological and geological data allow us to reconstruct magma pathways and long-term magma differentiation and assembly processes. However, our ability to detect and reconstruct the short-term dynamics related to active intrusive episodes in mountain chains is embryonic, lacking recognized geophysical signals...
January 2018: Science Advances
https://www.readbyqxmd.com/read/29326095/development-of-a-maternal-newborn-and-child-mhealth-intervention-in-thai-nguyen-province-vietnam-protocol-for-the-mmom-project
#12
Bronwyn McBride, Liem Thanh Nguyen, David Wiljer, Nguyen C Vu, Cuong K Nguyen, John O'Neil
BACKGROUND: Ethnic minority women (EMW) living in mountainous areas of northern Vietnam have disproportionately high infant and maternal mortality rates as a result of low maternal health knowledge, poverty, and remoteness from low-capacity health centers. OBJECTIVE: The objective of this study was to describe the protocol for the development and evaluation of the mMom intervention, which is an integrated mobile health (mHealth) system designed to improve maternal and infant health knowledge, and behavior among women in remote areas of Thai Nguyen, Vietnam...
January 11, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29324979/under-pressure-epicormic-shoots-and-traumatic-growth-zones-in-high-latitude-triassic-trees-from-east-antarctica
#13
Anne-Laure Decombeix, Rudolph Serbet, Edith L Taylor
Background and Aims: Investigating the biology of trees that were growing at high latitudes during warmer geological periods is key to understanding the functioning of both past and future forest ecosystems. The aim of this study is to report the first co-occurrence of epicormic shoots and traumatic growth zones in fossil trees from the Triassic of Antarctica and to discuss their biological and environmental implications. Methods: Permineralized woods bearing scars of epicormic shoots were collected from the Triassic Fremouw Formation in Gordon Valley, Central Transantarctic Mountains, Antarctica in 2010...
January 6, 2018: Annals of Botany
https://www.readbyqxmd.com/read/29323209/hydrological-simulation-and-uncertainty-analysis-using-the-improved-topmodel-in-the-arid-manas-river-basin-china
#14
Lianqing Xue, Fan Yang, Changbing Yang, Guanghui Wei, Wenqian Li, Xinlin He
Understanding the mechanism of complicated hydrological processes is important for sustainable management of water resources in an arid area. This paper carried out the simulations of water movement for the Manas River Basin (MRB) using the improved semi-distributed Topographic hydrologic model (TOPMODEL) with a snowmelt model and topographic index algorithm. A new algorithm is proposed to calculate the curve of topographic index using internal tangent circle on a conical surface. Based on the traditional model, the improved indicator of temperature considered solar radiation is used to calculate the amount of snowmelt...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322582/large-scale-disturbance-legacies-and-the-climate-sensitivity-of-primary-picea-abies-forests
#15
Jonathan S Schurman, Volodymyr Trotsiuk, Radek Bače, Vojtěch Čada, Shawn Fraver, Pavel Janda, Dominik Kulakowski, Jana Labusova, Martin Mikoláš, Thomas A Nagel, Rupert Seidl, Michal Synek, Kristýna Svobodová, Oleh Chaskovskyy, Marius Teodosiu, Miroslav Svoboda
Determining the drivers of shifting forest disturbance rates remains a pressing global change issue. Large-scale forest dynamics are commonly assumed to be climate driven, but appropriately scaled disturbance histories are rarely available to assess how disturbance legacies alter subsequent disturbance rates and the climate sensitivity of disturbance. We compiled multiple tree-ring based disturbance histories from primary Picea abies forest fragments distributed throughout five European landscapes spanning the Bohemian Forest and the Carpathian Mountains...
January 11, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29321908/rapid-song-divergence-leads-to-discordance-between-genetic-distance-and-phenotypic-characters-important-in-reproductive-isolation
#16
Emmanuel C Nwankwo, Chryso Th Pallari, Louis Hadjioannou, Andreas Ioannou, Ronald K Mulwa, Alexander N G Kirschel
The criteria for species delimitation in birds have long been debated, and several recent studies have proposed new methods for such delimitation. On one side, there is a large consensus of investigators who believe that the only evidence that can be used to delimit species is molecular phylogenetics, and with increasing numbers of markers to gain better support, whereas on the other, there are investigators adopting alternative approaches based largely on phenotypic differences, including in morphology and communication signals...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29321902/early-phenology-and-growth-trait-variation-in-closely-related-european-pine-species
#17
Witold Wachowiak, Annika Perry, Kevin Donnelly, Stephen Cavers
Closely related taxa occupying different environments are valuable systems for studying evolution. In this study, we examined differences in early phenology (bud set, bud burst) and early growth in a common garden trial of closely related pine species: Pinus sylvestris, P. mugo, and P. uncinata. Seeds for the trial were sourced from populations across the ranges of each species in Europe. Over first 4 years of development, clear differences were observed between species, while the most significant intraspecific differentiation was observed among plants from P...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29321860/incorporating-variability-in-simulations-of-seasonally-forced-phenology-using-integral-projection-models
#18
Devin W Goodsman, Brian H Aukema, Nate G McDowell, Richard S Middleton, Chonggang Xu
Phenology models are becoming increasingly important tools to accurately predict how climate change will impact the life histories of organisms. We propose a class of integral projection phenology models derived from stochastic individual-based models of insect development and demography. Our derivation, which is based on the rate summation concept, produces integral projection models that capture the effect of phenotypic rate variability on insect phenology, but which are typically more computationally frugal than equivalent individual-based phenology models...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29321444/agricultural-aspects-of-radiocontamination-induced-by-the-fukushima-nuclear-accident-a-survey-of-studies-by-the-univ-of-tokyo-agricultural-dept-2011-2016
#19
Tomoko M Nakanishi
Immediately after the Fukushima nuclear power plant accident, a team of 40-50 researchers at the Graduate School of Agricultural and Life Sciences at the University of Tokyo began to analyze the behavior of radioactive materials in the fallout regions. The fallout has remained in situ and become strongly adsorbed within the soil over time. 137Cs was found to bind strongly to the fine clay, weathered biotite, and organic matter in the soil; therefore, it has not mobilized from mountainous regions, even after heavy rainfall...
2018: Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
https://www.readbyqxmd.com/read/29321345/genetic-variability-and-structure-of-an-isolated-population-of-ambystoma-altamirani-a-mole-salamander-that-lives-in-the-mountains-of-one-of-the-largest-urban-areas-in-the-world
#20
Rosa-Laura Heredia-Bobadilla, Octavio Monroy-Vilchis, Martha M Zarco-González, Daniel Martínez-Gómez, Germán David Mendoza-Martínez, Armando Sunny
Amphibians are globally threatened by habitat loss and fragmentation; species within the order Ambystoma are not the exception, as there are 18 species of mole salamanders in México, of which 16 are endemic and all species are under some national or international status of protection. The mole salamander, Ambystoma altamirani is a microendemic species, which is distributed in central México, within the trans-Mexican volcanic belt, and is one of the most threatened species due to habitat destruction and the introduction of exotic species...
December 2017: Journal of Genetics
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