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Altitude illness

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https://www.readbyqxmd.com/read/29095325/charcot-marie-tooth-disease-1x-simulating-paraparetic-guillain-barre-syndrome
#1
Dimitrios Parissis, Panagiotis Ioannidis, Georgios Papadopoulos, Dimitrios Karacostas
X-linked Charcot-Marie-Tooth disease (CMT 1X) is the second most common form of inherited demyelinating neuropathy. It is established that patients suffering from CMT 1X can have episodes of hemiparesis, paraparesis, quadriparesis, ataxia, aphasia, and dysarthria, which can be fully reversible, and 'trigger' factors for these episodes are usually febrile illness, high altitudes, hyperventilation, and physical activity. We describe a 22-year-old patient with a history of viral infection and sleep deprivation who presented to our department because of acute difficulty in walking and neurophysiological findings suggesting Guillain-Barre syndrome...
November 2017: Neurologist
https://www.readbyqxmd.com/read/29046183/you-re-the-flight-surgeon
#2
(no author information available yet)
Pelligra S. You're the flight surgeon: decompression illness following altitude chamber exposure. Aerosp Med Hum Perform. 2017; 88(11):1052-1055.
November 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29020216/outpatient-management-of-children-with-world-health-organization-chest-indrawing-pneumonia-implementation-risks-and-proposed-solutions
#3
Eric D McCollum, Amy Sarah Ginsburg
This Viewpoints article details our recommendation for the World Health Organization Integrated Management of Childhood Illness guidelines to consider additional referral or daily monitoring criteria for children with chest indrawing pneumonia in low-resource settings. We review chest indrawing physiology in children and relate this to the risk of adverse pneumonia outcomes. We believe there is sufficient evidence to support referring or daily monitoring of children with chest indrawing pneumonia and signs of severe respiratory distress, oxygen saturation <93% (when not at high altitude), moderate malnutrition, or an unknown human immunodeficiency virus (HIV) status in an HIV-endemic setting...
June 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28982709/the-british-services-dhaulagiri-medical-research-expedition-2016-a-unique-military-and-civilian-research-collaboration
#4
Adrian Mellor, J Bakker-Dyos, M Howard, C Boos, M Cooke, E Vincent, P Scott, J O'Hara, S B Clarke, M Barlow, J Matu, K Deighton, N Hill, C Newman, R Cruttenden, D Holdsworth, D Woods
INTRODUCTION: High-altitude environments lead to a significant physiological challenge and disease processes which can be life threatening; operational effectiveness at high altitude can be severely compromised. The UK military research is investigating ways of mitigating the physiological effects of high altitude. METHODS: The British Service Dhaulagiri Research Expedition took place from March to May 2016, and the military personnel were invited to consent to a variety of study protocols investigating adaptation to high altitudes and diagnosis of high-altitude illness...
October 5, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28923144/in-flight-ultraviolet-radiation-on-commercial-airplanes
#5
Pascal Cadilhac, Marie-Christine Bouton, Monique Cantegril, Catherine Cardines, Alain Gisquet, Noël Kaufman, Michel Klerlein
INTRODUCTION: Epidemiological studies suggest that pilots and cabin crew have higher incidences and mortality rates of cutaneous malignant melanoma than those of the general population. Exposure to UV radiation is one of the main risk factors for this type of cancer. The aim of this study was to evaluate the level of UV radiation in an airliner in flight. METHODS: Measurements were taken with a three sensor-integrated electronics UV radiometer (A, B, and C) during 14 flights from July to October 2016...
October 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28923020/caretakers-understanding-of-malaria-use-of-insecticide-treated-net-and-care-seeking-behavior-for-febrile-illness-of-their-children-in-ethiopia
#6
Zewdie Birhanu, Yemane Ye-Ebiyo Yihdego, Delenasaw Yewhalaw
BACKGROUND: Local understandings of malaria and use of preventive measures-are critical factors in sustained control of malaria. This study assessed caretakers' knowledge on malaria, use of Long Lasting Insecticide Treated Nets (LLINs) and care-seeking behavior for their children's illness in different malaria transmission settings of Ethiopia. METHODS: Data were collected from 709 caretakers of children of 2-9 years of age during in 2016. A standard questionnaire was used to assess caretakers' perceptions of malaria, use of LLIN and care seeking behavior for febrile illness of children aged 2-9 years...
September 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28919307/a-journey-between-high-altitude-hypoxia-and-critical-patient-hypoxia-what-can-it-teach-us-about-compression-and-the-management-of-critical-disease
#7
M L Avellanas Chavala
High altitude sickness (hypobaric hypoxia) is a form of cellular hypoxia similar to that suffered by critically ill patients. The study of mountaineers exposed to extreme hypoxia offers the advantage of involving a relatively homogeneous and healthy population compared to those typically found in Intensive Care Units (ICUs), which are heterogeneous and generally less healthy. Knowledge of altitude physiology and pathology allows us to understanding how hypoxia affects critical patients. Comparable changes in mitochondrial biogenesis between both groups may reflect similar adaptive responses and suggest therapeutic interventions based on the protection or stimulation of such mitochondrial biogenesis...
September 14, 2017: Medicina Intensiva
https://www.readbyqxmd.com/read/28910201/reentry-high-altitude-pulmonary-edema-in-the-himalayas
#8
Santosh Baniya, Christopher Holden, Buddha Basnyat
Baniya, Santosh, Christopher Holden, and Buddha Basnyat. Reentry high altitude pulmonary edema in the Himalayas. High Alt Med Biol. 16:000-000, 2017.-Reentry high altitude pulmonary edema (HAPE), a subset of HAPE, is a well recognized, life-threatening illness documented almost exclusively in the North and South Americans, who live at high altitude (>2500 m) and return to their homes after a brief sojourn of days to months at lower altitude. This phenomenon has not been reported in Sherpas or other people of Tibetan origin in Nepal or India...
September 14, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28828048/initial-evaluation-and-key-principles-of-critically-ill-pediatric-patient-aerial-transport
#9
Constanta Pick
Recent advances in more efficient communications, modern telemedicine systems, medical progress, better training of the medical professionals with the possibility of sub-specialisation has led to shorter transfer times in safer conditions of this and overall affording a better chance of survival. High altitude air transport has considerable implications on the respiratory system's efficiency. Caregiver selection is key in avoiding the dangers of debilitating altitude sickness on the medical team. Minimizing physiological or anatomical derangements and minimizing potential complications in the very small critically ill patients while achieving short transfer times are major objectives...
December 2016: Mædica
https://www.readbyqxmd.com/read/28810235/obesity-as-a-conditioning-factor-for-high-altitude-diseases
#10
Rocío San Martin, Julio Brito, Patricia Siques, Fabiola León-Velarde
Obesity, a worldwide epidemic, has become a major health burden because it is usually accompanied by an increased risk for insulin resistance, diabetes, hypertension, cardiovascular diseases, and even some kinds of cancer. It also results in associated increases in healthcare expenditures and labor and economic consequences. There are also other fields of medicine and biology where obesity or being overweight play a major role, such as high-altitude illnesses (acute mountain sickness, hypoxic pulmonary hypertension, and chronic mountain sickness), where an increasing relationship among these two morbid statuses has been demonstrated...
2017: Obesity Facts
https://www.readbyqxmd.com/read/28781177/impact-of-a-newly-constructed-motor-vehicle-road-on-altitude-illness-in-the-nepal-himalayas
#11
Jonathan Reisman, Dinesh Deonarain, Buddha Basnyat
OBJECTIVE: This study investigated the impact that motor vehicle travel along a newly constructed road has on altitude illness (including acute mountain sickness, high-altitude cerebral edema, and high-altitude pulmonary edema). The new road from Besisahar (760 m) to Manang (3540 m) in Nepal was completed in December 2014. METHODS: We enrolled all patients diagnosed with altitude illness at the Himalayan Rescue Association Manang clinic in fall 2016. Phi coefficients were calculated to test for an association between Nepali ethnicity and rapid ascent by motor vehicle...
August 3, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28720255/altitude-related-illnesses
#12
Roberto Alfonso Accinelli, Lidia Marianella López
No abstract text is available yet for this article.
July 15, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28716290/yarsagumba-fungus-health-problems-in-the-himalayan-gold-rush
#13
Pranawa Koirala, Bidur Pandit, Pratibha Phuyal, Ken Zafren
INTRODUCTION: Seasonal migration of people in search of Yarsagumba fungus creates a population of collectors that faces hardship and health risks in austere high-altitude settings. METHODS: In 2016, our 4-person team performed a 2-day health-needs survey of people collecting Yarsagumba fungus near the village of Yak Kharka (4020 m) in the Manang District of Nepal. RESULTS: There were approximately 800 people, both male and female, from age 10 to over 60, collecting Yarsagumba fungus...
July 14, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28696953/out-of-air-is-going-to-high-altitude-safe-for-your-patient
#14
Ann M Mendenhall, Christopher P Forest
As more people travel to high altitudes for recreation or work, more travelers with underlying medical conditions will need advice before traveling or treatment for altitude illness. This article focuses on the two main issues for travelers: whether travel to a high altitude will have a negative effect on their underlying medical condition and whether the medical condition increases the patient's risk of developing altitude illness. Although patients with severe pulmonary or cardiac conditions are most at risk in the hypoxic environment, other conditions such as diabetes and pregnancy warrant attention as well...
August 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28695835/the-concept-of-travel-medicine-and-the-actual-situation-of-travel-related-illnesses
#15
Varol Tunalı, Nevin Turgay
Travel medicine defines all diseases and medical situations that are related to travel. Travel medicine comprises infectious diseases, traumas, altitude sickness, sun burns, embolisms, jet lag, and many more travel-related situations. With the increasing possibility and ease of travel, the number of people who have travelled internationally has exceeded 1.13 billion in 2014, and the revenues of international travel have exceeded 1.25 trillion dollars. With every passing day, international travels are shifting toward the developing countries and to more exotic regions of the world, and travelers tend to be more adventurous and daring, thereby increasing risky behaviors during travels...
June 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28653390/interventions-for-preventing-high-altitude-illness-part-1-commonly-used-classes-of-drugs
#16
REVIEW
Víctor H Nieto Estrada, Daniel Molano Franco, Roger David Medina, Alejandro G Gonzalez Garay, Arturo J Martí-Carvajal, Ingrid Arevalo-Rodriguez
BACKGROUND: High altitude illness (HAI) is a term used to describe a group of cerebral and pulmonary syndromes that can occur during travel to elevations above 2500 metres (8202 feet). Acute hypoxia, acute mountain sickness (AMS), high altitude cerebral oedema (HACE) and high altitude pulmonary oedema (HAPE) are reported as potential medical problems associated with high altitude. In this review, the first in a series of three about preventive strategies for HAI, we assess the effectiveness of six of the most recommended classes of pharmacological interventions...
June 27, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28609593/travelling-safely-to-places-at-high-altitude-understanding-and-preventing-altitude-illness
#17
Ivan Parise
BACKGROUND: Greater numbers of people are travelling to places at high altitude each year. Altitude illness is common in places at high altitude and may be life-threatening. General practitioners (GPs) are best placed to provide evidence-based advice to keep travellers well informed of the possible risks they may encounter in places at high altitude. OBJECTIVE: The aim of this article is to review knowledge on altitude illness in order to help GPs assist patients to travel safely to places at high altitude...
June 2017: Australian Family Physician
https://www.readbyqxmd.com/read/28582330/high-altitude-illness-in-the-pediatric-population-a-review-of-the-literature-on-prevention-and-treatment
#18
Vanessa Garlick, Anne O'Connor, Catherine D Shubkin
PURPOSE OF REVIEW: Increasing numbers of children are now traveling to high-altitude destinations, and pediatricians often see these children prior to and immediately following their travels. Thus, pediatricians have the opportunity to provide guidance for the prevention of altitude illness and must treat high-altitude illness (HAI) in some circumstances. This review will examine guidelines for prevention and management of HAI in the pediatric population. RECENT FINDINGS: Recent research has examined children's short-term cardiorespiratory adaptation to high altitude, incidence of acute mountain sickness, hypoxic ventilator response, and maximal exercise capacity...
August 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28509579/findings-of-cognitive-impairment-at-high-altitude-relationships-to-acetazolamide-use-and-acute-mountain-sickness
#19
Lara Phillips, Buddha Basnyat, Yuchiao Chang, Erik R Swenson, N Stuart Harris
Phillips, Lara, Buddha Basnyat, Yuchiao Chang, Erik R. Swenson, and N. Stuart Harris. Findings of cognitive impairment at high altitude: relationships to acetazolamide use and acute mountain sickness. High Alt Med Biol. 18:121-127, 2017. OBJECTIVE: Acute mountain sickness (AMS) is defined by patient-reported symptoms using the Lake Louise Score (LLS), which provides limited insight into any possible underlying central nervous system (CNS) dysfunction. Some evidence suggests AMS might coexist with altered neural functioning...
June 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28433745/hypoxia-augments-lps-induced-inflammation-and-triggers-high-altitude-cerebral-edema-in-mice
#20
Yanzhao Zhou, Xin Huang, Tong Zhao, Meng Qiao, Xingnan Zhao, Ming Zhao, Lun Xu, Yongqi Zhao, Liying Wu, Kuiwu Wu, Ruoli Chen, Ming Fan, Lingling Zhu
High altitude cerebral edema (HACE) is a life-threatening illness that develops during the rapid ascent to high altitudes, but its underlying mechanisms remain unclear. Growing evidence has implicated inflammation in the susceptibility to and development of brain edema. In the present study, we investigated the inflammatory response and its roles in HACE in mice following high altitude hypoxic injury. We report that acute hypobaric hypoxia induced a slight inflammatory response or brain edema within 24h in mice...
April 20, 2017: Brain, Behavior, and Immunity
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