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https://www.readbyqxmd.com/read/29449731/mixed-malignant-mullerian-tumor-with-neuroendocrine-features-in-an-irradiated-uterus-for-cervical-carcinoma-a-unique-association-a-morphological-immunohistochemisty-and-ultrastructural-study
#1
V G Vellone, B Spina, F Grillo, P Calamaro, F Sarocchi, P Sala, S Ferrero, E Fulcheri
Chemo-radiation represents an effective therapy for carcinoma of the uterine cervix. The endometrium may however receive a consistent dose of mutagenic radiations and patients may have an increased risk of secondary malignancies. Endometrial mixed malignant mullerian tumor (MMMT) is a rare, highly aggressive disease, and neuroendocrine features are even rarer. A 68 years old woman underwent radio-chemotherapy for a squamous cell carcinoma of the cervix. Follow up was uneventful until, eight years after radio-chemotherapy, imaging exams detected a diffuse enlargement of the uterine body...
December 2017: Pathologica
https://www.readbyqxmd.com/read/29447856/laparoscopic-sacrohysteropexy-in-a-12-weeks-pregnant-woman
#2
Berna Haliloglu Peker, Erdin Ilter, Hakan Peker, Aygen Celik, Ali Gursoy, Onur Gunaldi
STUDY OBJECTIVE: To demonstrate laparoscopic sacrohysteropexy for a case of uterine prolapse in a 12 weeks and 3 days pregnant woman. To our knowledge, this is the first case of laparoscopic sacrohysteropexy performed at 12th weeks of gestation to be reported in literature. DESIGN: A step-by-step explanation of the surgical procedure (Canadian Task Force classification III) SETTING: Uterine prolapse is very rare condition manifesting in an estimated 10000 to 15000 pregnancies (1)...
February 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29441095/off-line-magnetic-resonance-imaging-navigation-of-cervix-cancer-brachytherapy-in-patients-with-risk-factors-for-uterine-perforation
#3
Noora Mohammed Al-Hammadi, Suparna Halsnad Chandramouli, Rabih Hammoud, Primoz Petric
Purpose: There are no reports on pre-insertion identification of cervix cancer patients at risk for uterine perforation during brachytherapy (BT). Our aim was to assess the incidence of risk factors in our patient cohort, and assess feasibility of a novel technique of magnetic resonance imaging (MRI)-guided navigation for applicator insertion (NAI) in high-risk cases. Material and methods: All patients with locally advanced cervical cancer, treated with image guided adaptive BT at our department between October 2013 and June 2017 were considered for analysis...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29423555/second-malignancies-after-hematopoietic-stem-cell-transplantation
#4
REVIEW
Ivetta Danylesko, Avichai Shimoni
Second malignancies are a rare but well-defined late complication after autologous and allogeneic hematopoietic stem-cell transplantation (SCT). Solid malignancies occur in up to 15% of patients 15 years after SCT with myeloablative conditioning, with no plateau in the incidence rates. They are responsible for 5-10% of late deaths after SCT. The incidence is increased with advanced age at SCT. The major risk factors are the use of total body irradiation, which is associated with adenocarcinomas and with chronic graft-versus-host disease which is associated with squamous cell cancers...
February 8, 2018: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29423520/cisplatin-chemoradiotherapy-vs-radiotherapy-in-figo-stage-iiib-squamous-cell-carcinoma-of-the-uterine-cervix-a-randomized-clinical-trial
#5
Shyamkishore Shrivastava, Umesh Mahantshetty, Reena Engineer, Supriya Chopra, Rohini Hawaldar, Vinod Hande, Rajendra A Kerkar, Amita Maheshwari, T S Shylasree, Jaya Ghosh, Jyoti Bajpai, Lavanya Gurram, Seema Gulia, Sudeep Gupta
Importance: The evidence for concurrent chemoradiotherapy (CT-RT) in International Federation of Gynecology and Obstetrics (FIGO) stage IIIB squamous cell carcinoma of the uterine cervix is not robust. This study reports the final results of a randomized clinical trial of concurrent cisplatin-based CT-RT and radiotherapy alone (RT) in women with FIGO stage IIIB squamous cell carcinoma of the uterine cervix. Objective: To investigate the benefit of concurrent CT-RT in FIGO stage IIIB squamous cell carcinoma of the uterine cervix...
February 8, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29415121/mayer-rokitansky-kuster-hauser-syndrome-a-unique-case-presentation
#6
Bao T Nguyen, Katherine L Dengler, Rhiana D Saunders
Background: Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a congenital condition characterized by aplasia of the vagina with or without concurrent uterine and/or cervical aplasia. Type II (MURCS) is a rare form involving MUllerian agenesis, Renal agenesis, and Cervicothoracic Somite anomalies. Case: A 17-yr-old virginal female presented for evaluation of primary amenorrhea and pelvic pain. Her medical history was significant for a bicuspid aortic valve and right radial dysplasia...
February 5, 2018: Military Medicine
https://www.readbyqxmd.com/read/29404709/the-pattern-is-the-issue-recent-advances-in-adenocarcinoma-of-the-uterine-cervix
#7
REVIEW
Andres A Roma, Oluwole Fadare
In this article, we review a novel risk stratification system for endocervical adenocarcinoma, developed by an international consortium of pathologists after reviewing over 350 such tumors. Their analysis culminated in a three-tiered histopathologic system based on morphologic examination of the tumor, independent of clinical features and stage (depth of invasion). It resulted in better determination of patients' tumors and likelihood of lymph node metastasis as well as aggressive behavior. A non-destructive pattern (that in some cases was in the histologic differential diagnosis with adenocarcinoma in situ) had an indolent behavior and was labeled pattern A...
February 5, 2018: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/29400017/trends-in-single-women-with-malignancy-of-the-uterine-cervix-in-united-states
#8
Hiroko Machida, Erin A Blake, Sarah E Eckhardt, Tsuyoshi Takiuchi, Brendan H Grubbs, Mikio Mikami, Lynda D Roman, Koji Matsuo
OBJECTIVE: To examine trends and characteristics of single women with malignancy of the uterine cervix. METHODS: This is a retrospective observational study examining the United States population-based tumor registry (the Surveillance, Epidemiology, and End Results program). Time-specific trends in single marital status were examined in 3,294,208 women among 12 common female malignancies including 87,151 women with uterine cervical malignancy between 1973 and 2013...
December 27, 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29393245/serous-carcinoma-of-the-uterine-cervix-an-extremely-rare-aggressive-entity-a-literature-review
#9
Joanna Jonska-Gmyrek, Agnieszka Zolciak-Siwinska, Leszek Gmyrek, Wojciech Michalski, Grazyna Poniatowska, Malgorzata Fuksiewicz, Pawel Wiechno, Jakub Kucharz, Maria Kowalska, Beata Kotowicz
BACKGROUND/AIMS: Serous carcinoma of the uterine cervix (USCC) is an extremely rare subtype. To establish the treatment strategy in patients with USCC is an important issue. METHODS: MEDLINE (PubMed) was searched for all articles published after the first publication by Lurie et al. [Eur J Obstet Gynecol Reprod Biol 1991; 40: 79-81], reporting woman diagnosed with USCC. Because of limited numbers of studies on the topic of the study, we could not keep a restriction of eliminating smaller sample sizes...
January 23, 2018: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/29373905/significance-of-dna-replication-licensing-proteins-mcm2-mcm5-and-cdc6-p16-and-p63-as-markers-of-premalignant-lesions-of-the-uterine-cervix-its-usefulness-to-predict-malignant-potential
#10
V N Saritha, V S Veena, K M Jagathnath Krishna, Thara Somanathan, K Sujathan
Cervical cancer continues to be a leading cancer among women in many parts of the world. Nation-wide screening with the Pap smear has not been implemented in India due to the lack of adequately trained cytologists. Identification of biomarkers to predict malignant potential of the identified low risk lesions is essential to avoid excessive retesting and follow up. The current study analyzed the expression patterns of DNA replication licensing proteins, proliferation inhibitor protein p16INK4A and tumor suppresser protein p63 in cervical tissues and smears to assess the ability of these proteins to predict progression...
January 27, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29373116/uncommon-hereditary-gynaecological-tumour-syndromes-pathological-features-in-tumours-that-may-predict-risk-for-a-germline-mutation
#11
REVIEW
Karuna Garg, Anthony N Karnezis, Joseph T Rabban
The most common hereditary gynaecological tumour syndromes are hereditary breast and ovarian cancer syndrome and Lynch syndrome. However, pathologists also may encounter gynaecological tumours in women with rare hereditary syndromes. Many of these tumours exhibit distinctive gross and microscopic features that are associated with a risk for an inherited gene mutation. The sensitivity and specificity of these tumour pathology features for predicting an inherited mutation vary depending on the syndrome. By recognising these tumour features, pathologists may potentially contribute to the diagnosis of an unsuspected syndrome by recommending referral of the patient for formal risk assessment by genetic counselling...
January 17, 2018: Pathology
https://www.readbyqxmd.com/read/29372165/gastric-type-mucinous-endocervical-adenocarcinoma-of-the-uterine-cervix-very-rare-and-interesting-case
#12
Chul Min Park, Hyun Min Koh, Soyun Park, Hye Sim Kang, Soon Sup Shim, Sung Yob Kim
Gastric type mucinous endocervical adenocarcinomas of the uterine cervix (GAC) are a newly classified mucinous subtype with morphologically in 2014, WHO. They have a much more aggressiveness and show unusual metastatic patterns compared to usual type endocervical adenocarcinoma. They tend to present at higher stage and even in stage I, they have worse survival. Therefore, differential diagnosis of GAC from the usual type of endocervical adenocarcinoma is very important because they are related to a significant risk of recurrence and decreased 5-year disease-specific survival...
January 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29371171/simplified-laparoscopic-sacrohysteropexy
#13
Haider Jan, Vishalli Ghai, Ranee Thakar
STUDY OBJECTIVE: To demonstrate a simplified technique of performing a laparoscopic sacrohysteropexy for uterine prolapse DESIGN: Technical video demonstrating simplified method of a laproscopic sacrohysteropexy (Canadian Task force classification level III). SETTING: Benign gynaecology department at a University Hospital. INTERVENTION: A 38-year old woman with grade 3 uterine descent presented requesting surgical management for symptomatic prolapse...
January 22, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29370509/colloid-carcinoma-of-the-uterine-cervix-and-its-immunohistochemical-analysis-a-case-report
#14
Nermin Koc, Sevcan Arzu Arinkan, Nurver Ozel Ozbay, Selcuk Selcuk
Colloid carcinoma, which is a very rare tumor of the uterine cervix, is composed of an excessive amount of mucus and a relative paucity of tumoral glandular cells within them. Herein, we report a rare case of colloid carcinoma of the cervix with adenocarcinoma in situ (AIS), intestinal and usual types, and endocervical adenocarcinoma (usual type) components. We also discuss the morphological and immunohistochemical characteristics of this tumor. A 51-year-old woman was referred to our outpatient clinic with the symptom of genital bleeding lasting for 5 months...
January 2018: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29369931/identifying-acute-cervicitis-in-an-era-of-less-frequent-routine-gynecologic-examinations
#15
Margaret Allen
Acute inflammation of the uterine cervix can lead to serious problems such as pelvic inflammatory disease (PID), endometritis, and complications of pregnancy and childbirth. As intervals for routine gynecologic screening examinations lengthen, cervical infections, especially if asymptomatic, may be missed. Annual wellness examinations and other patient visits outside routine gynecologic cancer screening visits should include brief evaluation with sexual risk assessment and a gynecologic examination if indicated...
February 2018: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/29359610/effectiveness-of-a-bipolar-vessel-sealant-device-for-ovariohysterectomy-in-cats-with-pyometra
#16
Jean-François Boursier, Jean Bassanino, Dimitri Leperlier
Objectives The objective was to describe the use of a bipolar vessel sealant device for complete ovariohysterectomy in cats - both the ovarian pedicle and the uterine body and vessels - and to report on the feasibility of ovariohysterectomy in cats with pyometra. Methods Cats with confirmed pyometra and whose owners agreed to the surgical procedure were prospectively included in the study. Ovaries were visualised and the vessel sealant device was used to coagulate and cut the suspensory ligament, the ovarian pedicle and the broad ligament up to the level of the uterine body...
January 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29354932/-effects-of-the-combined-therapy-of-heat-sensitive-moxibustion-and-acupoint-injection-on-endometrial-receptivity-of-hypdrosalphinx-infertility-in-the-patients-after-hysteroscopy-and-laparoscopy
#17
Yanling Liu, Lizhen Pan, Ying Wang
OBJECTIVE: To explore the effects of the combined therapy of heat sensitive moxibustion and acupoint injection on endometrial receptivity of hypdrosalphinx infertility in the patients after hysteroscopy and laparoscopy on the base of routine post-operative anti-inflammation. METHODS: A total of 210 patients of hypdrosalphinx infertility after hysteroscopy and laparoscopy were divided into a combined therapy group, a heat sensitive moxibustion group and a control group, 70 cases in each one according to the random number table...
January 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29346219/pancreatic-metastases-as-the-initial-manifestation-of-a-neuroendocrine-carcinoma-of-the-uterine-cervix
#18
Maria Ana C B Kopke Túlio, Mariana S F Horta, Miguel C S Bispo, Tiago S N Bana E Costa, Cristina M D B R Chagas
No abstract text is available yet for this article.
February 2018: Pancreas
https://www.readbyqxmd.com/read/29333882/vaginoplasty-what-s-new-from-1946-to-date-commentary-on-vaginoplasty-with-acellular-dermal-matrix-after-radical-resection-for-carcinoma-of-the-uterine-cervix
#19
Roberto Cuomo, Luca Grimaldi, Cesare Brandi, Andrea Sisti, Giuseppe Nisi
No abstract text is available yet for this article.
January 15, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29327473/risk-assessment-for-metalworking-fluids-and-cancer-outcomes
#20
Robert M Park
BACKGROUND: Metalworking fluids (MWF) are complex mixtures with dermal and inhalation exposure. Published reports reveal excess cancer risk. METHODS: Using published findings exposure response was derived for each attributable cancer site. Aggregate excess lifetime risk was estimated by applying a lifetable calculation. RESULTS: Cancer sites contributing the most attributable cases were larynx, esophagus, brain, female breast, and uterine cervix...
January 12, 2018: American Journal of Industrial Medicine
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