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https://www.readbyqxmd.com/read/28107572/introduction-of-a-new-paediatric-asthma-guideline-effects-on-asthma-control-levels
#1
S C Hammer, L J H Sonneveld, K D G van de Kant, H J Hendriks, J W Heynens, R Droog, E Dompeling, Q Jöbsis
BACKGROUND: In 2008, a new national paediatric asthma management guideline based on the international Global Initiative for Asthma (GINA) guideline, was launched in the Netherlands. We studied whether asthma control and treatment regimens improved after introduction of the guideline by comparing survey data before and after the guideline introduction. METHODS: Two comparable groups of children (6-16 years) with asthma were included before (2004) and after (2013) the introduction of the guideline...
January 20, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28098171/metallurgical-investigation-on-fourth-century-bce-silver-jewellery-of-two-hoards-from-samaria
#2
D Ashkenazi, H Gitler, A Stern, O Tal
A fourth century BCE silver jewellery collection, which is part of two hoards of Samarian coins (the Samaria and Nablus Hoards), was studied by non-destructive analyses. The collection, which consists of pendants, rings, beads and earrings, had been examined by visual testing, multi-focal microscopy and SEM-EDS analysis. In order to enhance our knowledge of past technologies of silver jewellery production, we developed a metallurgical methodology based on the chemical composition of the joints and bulk. The results show that all artefacts are made of silver containing a small percentage of copper...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28094664/feasibility-and-acceptability-of-active-book-clubs-in-cancer-survivors-an-explorative-investigation
#3
Nanna Maria Hammer, Lisbeth Kofoed Egestad, Susanne Grøn Nielsen, Eik Bjerre, Christoffer Johansen, Ingrid Egerod, Bernardine Pinto, Julie Midtgaard
BACKGROUND: While the increasing number of people surviving cancer is promising, the long-term health effects warrant broad, innovative interventions. We investigated the feasibility and acceptability of a 24-week intervention called 'Active Book Club' comprising audio book listening, pedometer walking and supervised book club meetings. MATERIAL AND METHODS: An exploratory and descriptive design was applied. Qualitative data included baseline and post-intervention focus group interviews as well as post-intervention individual interviews...
January 17, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28093882/the-gastrointestinal-tract-of-farmed-mink-neovison-vison-maintains-a-diverse-mucosa-associated-microbiota-following-a-3-day-fasting-period
#4
Martin I Bahl, Anne S Hammer, Tove Clausen, Anabelle Jakobsen, Søren Skov, Lars Andresen
Although it is well documented that the gut microbiota plays an important role in health and disease in mammalian species, this area has been poorly studied among carnivorous animals, especially within the mustelidae family. The gastrointestinal tract of carnivores is characterized by its short length and fast transit time, as compared to omnivores and herbivores, which is due to the low level of inherent fermentation. Mink represents an example of this, which have a GI tract only four times the length of the body and a transit time of approximately 4-5 hr...
January 16, 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/28088041/the-role-of-the-ifg-and-psts-in-syntactic-prediction-evidence-from-a-parametric-study-of-hierarchical-structure-in-fmri
#5
William Matchin, Christopher Hammerly, Ellen Lau
Sentences encode hierarchical structural relations among words. Several neuroimaging experiments aiming to localize combinatory operations responsible for creating this structure during sentence comprehension have contrasted short, simple phrases and sentences to unstructured controls. Some of these experiments have revealed activation in the left inferior frontal gyrus (IFG) and posterior superior temporal sulcus (pSTS), associating these regions with basic syntactic combination. However, the wide variability of these effects across studies raises questions about this interpretation...
December 18, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28086755/vitamin-d-deficiency-as-a-risk-factor-for-dementia-a-systematic-review-and-meta-analysis
#6
Isolde Sommer, Ursula Griebler, Christina Kien, Stefanie Auer, Irma Klerings, Renate Hammer, Peter Holzer, Gerald Gartlehner
BACKGROUND: Sunlight exposure and high vitamin D status have been hypothesised to reduce the risk of developing dementia. The objective of our research was to determine whether lack of sunlight and hypovitaminosis D over time are associated with dementia. METHODS: We systematically searched MEDLINE (via PubMed), Cochrane Library, EMBASE, SCOPUS, Web of Science, ICONDA, and reference lists of pertinent review articles from 1990 to October 2015. We conducted random effects meta-analyses of published and unpublished data to evaluate the influence of sunlight exposure or vitamin D as a surrogate marker on dementia risk...
January 13, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28077020/relationship-between-18-f-flutemetamol-uptake-and-rbans-performance-in-non-demented-community-dwelling-older-adults
#7
Dustin B Hammers, Taylor J Atkinson, Bonnie C A Dalley, Kayla R Suhrie, Britney E Beardmore, Lance D Burrell, Kevin P Horn, Kelli M Rasmussen, Norman L Foster, Kevin Duff, John M Hoffman
OBJECTIVE: The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) has been used extensively for clinical care and in research for patients with mild cognitive impairment and Alzheimer's disease (AD); however, relatively few studies have evaluated the relationship between RBANS performance and AD imaging biomarkers. The purpose of the current study was to evaluate the association between a relatively new amyloid positron emission tomography imaging biomarker and performance on the RBANS...
January 12, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28076011/pulmonary-tuberculosis-role-of-radiology-in-diagnosis-and-management
#8
Arun C Nachiappan, Kasra Rahbar, Xiao Shi, Elizabeth S Guy, Eduardo J Mortani Barbosa, Girish S Shroff, Daniel Ocazionez, Alan E Schlesinger, Sharyn I Katz, Mark M Hammer
Tuberculosis is a public health problem worldwide, including in the United States-particularly among immunocompromised patients and other high-risk groups. Tuberculosis manifests in active and latent forms. Active disease can occur as primary tuberculosis, developing shortly after infection, or postprimary tuberculosis, developing after a long period of latent infection. Primary tuberculosis occurs most commonly in children and immunocompromised patients, who present with lymphadenopathy, pulmonary consolidation, and pleural effusion...
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28074914/hydroxysafflor-yellow-a-attenuates-the-expression-of-inflammatory-cytokines-in-acute-soft-tissue-injury
#9
Fang Dong, Changjiang Xue, Yu Wang, Yuanyuan Peng, Yadan Zhang, Ming Jin, Baoxia Zang
We examined the effect of hydroxysafflor yellow A (HSYA) on the inflammatory response to strike-induced acute soft tissue injury in rats. Soft tissue injury was induced in rat leg muscles using a strike hammer, followed by intraperitoneal administration of HSYA at 16, 32, or 64 mg/kg. After 24 h, the rats were anaesthetized, blood and muscle samples were taken. Plasma levels of interleukin (IL)-6, IL-1β, and tumour necrosis factor (TNF)-αwere measured by enzyme-linked immunosorbent assay. Total RNA and protein were isolated from muscle tissue to determine the mRNA levels of IL-6, IL-1β, TNF-α, vascular cell adhesion molecule (VCAM)-1, and intercellular adhesion molecule (ICAM)-1, and the protein level of phosphorylated p38 mitogen-activated protein kinase (MAPK)...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28073339/dermal-safety-assessment-of-arm-hammer-laundry-products-formulated-for-sensitive-skin
#10
Douglas M Frederick, Linda Vorwerk, Archana Gupta, Annahita Ghassemi
CONTEXT: The prevalence of sensitive skin among the general population in industrialized countries is reported to be over 50%. Sensitive skin subjects often report significant reactions to contact with cosmetics, soaps and other consumer products. OBJECTIVE: This paper describes the overall skin compatibility and mildness program for a newly developed, lightly fragranced, colorant free laundry product (i.e. Arm & Hammer™ Sensitive Skin plus Skin-Friendly Fresh Scent), specially formulated for individuals with sensitive skin...
January 11, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28070130/corrigendum-nanotechnology-for-environmentally-sustainable-electromobility
#11
Linda Ager-Wick Ellingsen, Christine Roxanne Hung, Guillaume Majeau-Bettez, Bhawna Singh, Zhongwei Chen, M Stanley Whittingham, Anders Hammer Strømman
No abstract text is available yet for this article.
January 10, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28069620/prenatal-exposure-to-antiepileptic-drugs-and-use-of-primary-healthcare-during-childhood-a-population-based-cohort-study-in-denmark
#12
Anne Mette Würtz, Dorte Rytter, Claus Høstrup Vestergaard, Jakob Christensen, Mogens Vestergaard, Bodil Hammer Bech
OBJECTIVE: Prenatal exposure to antiepileptic drugs (AEDs) has been associated with adverse outcomes in the offspring such as congenital malformations and neuropsychiatric disorders. The objective of this study was to investigate whether prenatal exposure to AEDs is also associated with more frequent use of primary healthcare during childhood. DESIGN: Population-based cohort study. SETTING: Nationwide national registers in Denmark. PARTICIPANTS: All live-born singletons in Denmark during 1997-2012 identified in the Danish National Patient Register and followed until 31 December 2013 (n=963 010)...
January 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28068449/repeated-cross-linking-after-a-short-time-does-not-provide-any-additional-biomechanical-stiffness-in-the-mouse-cornea-in-vivo
#13
David Tabibian, Sabine Kling, Arthur Hammer, Olivier Richoz, Farhad Hafezi
PURPOSE: To study whether repeated collagen cross-linking (CXL) performed in vivo in mice shows an additive effect on mechanical corneal stiffness. METHODS: In this experimental study, epithelium-off CXL was performed in a total of 18 eyes from male C57BL/6 mice, with 0.27%-riboflavin solution applied for 20 minutes, followed by ultraviolet-A (UVA) irradiation (365 nm, 9mW/cm(2)) for 2:50 minutes (fluence 1.53 J/cm(2)). CXL was performed as either a single (1×CXL) or a repeated (2×CXL) treatment...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28067446/synergistic-diastereo-and-enantioselective-functionalization-of-unactivated-alkyl-quinolines-with-%C3%AE-%C3%AE-unsaturated-aldehydes
#14
Marta Meazza, Fernando Tur, Niels Hammer, Karl Anker Jørgensen
A novel alkyl functionalization of unactivated alkyl quinolines has been developed combining InCl3 activation with organocatalytic activation of α,β-unsaturated aldehydes in a synergistic fashion. The reaction proceeds in a highly stereoselective manner as a sequence involving two consecutive synergistic catalytic cycles (Lewis acid- and iminium ion-catalyzed) and requires neither pre-activated alkyl quinoline substrates with electron-withdrawing substituents nor highly activated electrophiles. The reaction provides selectively double- or mono-addition products in good yields and high to excellent stereoselectivities...
January 9, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28067031/informed-consent-the-case-of-%C3%A2-omics%C3%A2-literacy
#15
Marilyn Hammer
The world of “-omics” is vastly changing the landscape of accelerated research and its translation to patient care. Understanding this complex science, particularly in the world of oncogenomics, can be daunting. Questions arise pertaining to how nurses can best educate patients who are forced to make difficult decisions without fully understanding to what they are consenting. This article follows a patient story that drives home the need to improve -omics literacy.
6, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28065167/diagnostic-utility-of-brain-activity-flow-patterns-analysis-in-attention-deficit-hyperactivity-disorder
#16
J Biederman, P Hammerness, B Sadeh, Z Peremen, A Amit, H Or-Ly, Y Stern, A Reches, A Geva, S V Faraone
BACKGROUND: A previous small study suggested that Brain Network Activation (BNA), a novel ERP-based brain network analysis, may have diagnostic utility in attention deficit hyperactivity disorder (ADHD). In this study we examined the diagnostic capability of a new advanced version of the BNA methodology on a larger population of adults with and without ADHD. METHOD: Subjects were unmedicated right-handed 18- to 55-year-old adults of both sexes with and without a DSM-IV diagnosis of ADHD...
January 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28065164/plasma-proteome-and-metabolome-characterization-of-an-experimental-human-thyrotoxicosis-model
#17
Maik Pietzner, Beatrice Engelmann, Tim Kacprowski, Janine Golchert, Anna-Luise Dirk, Elke Hammer, K Alexander Iwen, Matthias Nauck, Henri Wallaschofski, Dagmar Führer, Thomas F Münte, Nele Friedrich, Uwe Völker, Georg Homuth, Georg Brabant
BACKGROUND: Determinations of thyrotropin (TSH) and free thyroxine (FT4) represent the gold standard in evaluation of thyroid function. To screen for novel peripheral biomarkers of thyroid function and to characterize FT4-associated physiological signatures in human plasma we used an untargeted OMICS approach in a thyrotoxicosis model. METHODS: A sample of 16 healthy young men were treated with levothyroxine for 8 weeks and plasma was sampled before the intake was started as well as at two points during treatment and after its completion, respectively...
January 9, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28063861/common-and-distinct-characteristics-associated-with-trajectories-of-morning-and-evening-energy-in-oncology-patients-receiving-chemotherapy
#18
Hamza Abid, Kord M Kober, Betty Smoot, Steven M Paul, Marilyn Hammer, Jon D Levine, Kathryn Lee, Fay Wright, Bruce A Cooper, Yvette P Conley, Christine Miaskowski
CONTEXT: While energy conservation strategies are recommended in clinical practice guidelines, little is known about changes in energy levels in oncology patients undergoing cancer treatment. OBJECTIVES: To identify variations in the trajectories of morning and evening energy levels and to determine which characteristics predicted initial levels as well as the trajectories of morning and evening energy. METHODS: Outpatients receiving chemotherapy (CTX) completed demographic and symptom questionnaires six times over two CTX cycles...
January 4, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28063262/quantification-of-mechanical-dyssynchrony-in-growth-restricted-fetuses-and-normal-controls-using-speckle-tracking-echocardiography-ste
#19
Kristina Krause, Mareike Möllers, Kerstin Hammer, Maria Karina Falkenberg, Ute Möllmann, Dennis Görlich, Walter Klockenbusch, Ralf Schmitz
PURPOSE: To evaluate longitudinal mechanical dyssynchrony in normally grown fetuses by speckle tracking echocardiography (STE) and to compare longitudinal mechanical dyssynchrony in fetal growth restriction (FGR) with normal controls. MATERIALS AND METHODS: A prospective study was performed on 30 FGR and 62 normally grown fetuses, including 30 controls matched by gestational age, using STE and a transversal four-chamber view. Data analysis was carried out with a high frame rate of about 175 frames/s...
January 7, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28062629/unraveling-the-molecular-complexity-of-o-glycosylated-endogenous-n-terminal-pro-b-type-natriuretic-peptide-forms-in-blood-plasma-of-patients-with-severe-heart-failure
#20
Bernhard Halfinger, Angelika Hammerer-Lercher, Benno Amplatz, Bettina Sarg, Leopold Kremser, Herbert H Lindner
BACKGROUND: Currently, N-terminal pro-B-type natriuretic peptide (NT-proBNP) and its physiologically active counterpart, BNP, are most frequently used as biomarkers for diagnosis, prognosis, and disease monitoring of heart failure (HF). Commercial NT-proBNP and BNP immunoassays cross-react to varying degrees with unprocessed proBNP, which is also found in the circulation. ProBNP processing and immunoassay response are related to O-linked glycosylation of NT-proBNP and proBNP. There is a clear and urgent need to identify the glycosylation sites in the endogenously circulating peptides requested by the community to gain further insights into the different naturally occurring forms...
January 2017: Clinical Chemistry
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