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https://www.readbyqxmd.com/read/28812282/implementation-of-an-integrated-care-learning-experience-within-the-psychiatry-clerkship-nutrition-education-of-patients-with-serious-mental-illness
#1
Shinnyi Chou, Dana Raml, Ryan Hafner, Bill Baerentzen, Sharon Hammer
No abstract text is available yet for this article.
August 15, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28808673/data-on-the-impact-of-the-blood-sample-collection-methods-on-blood-protein-profiling-studies
#2
Maria Ilies, Cristina Adela Iuga, Felicia Loghin, Vishnu Mukund Dhople, Thomas Thiele, Uwe Völker, Elke Hammer
Complete blood protein profiles of 4 different blood sample collection methods (EDTA-, heparin- and citrate plasma and serum) were investigated and the data presented herein is an extension of the research article in Ilies et al. [1]. Specimens were depleted of 6 highly abundant proteins and protein profiling was assessed by nano-LC UDMS(E). Exhaustive protein sets and protein abundances before and after depletion are presented in tables and figures. Also, the core protein set and the unique proteins for each sample collection method previously described [1] are disclosed...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28807634/-severity-assessment-strategies-based-on-administrative-data-using-stroke-as-an-example
#3
Ingrid Schubert, Antje Hammer, Ingrid Köster
BACKGROUND AND OBJECTIVES: Information on disease severity is relevant for many studies with claims data in health service research, but only limited information is available in routine data. Stroke serves as an example, to analyse whether the combination of different information in claims data can provide insight into the severity of a disease. METHOD: As a first step, a literature search was conducted. Strategies to assess the severity of a disease by means of routine data were examined with regards and applicability to German sickness fund data...
August 11, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28805018/pain-catastrophizing-is-strongly-associated-with-subjective-outcomes-but-not-with-inflammatory-assessments-in-rheumatoid-arthritis-patients
#4
Hilde B Hammer, Till Uhlig, Tore K Kvien, Jon Lampa
OBJECTIVES: Pain catastrophizing is conceptualized as a negative cognitive-affective response to anticipated or actual pain and has been associated with important pain-related outcomes. The objective of this prospective study of established rheumatoid arthritis (RA) patients was to explore how pain catastrophizing was related to patient-reported outcomes (PROs), composite scores and assessments of inflammatory activity. METHODS: RA patients starting bDMARD were examined at baseline and after 1, 2, 3, 6 and 12 months with PROs (joint pain/patient's global VAS, MHAQ, RAID score), clinical and laboratory assessments (tender/swollen joint count, assessor's global VAS, ESR/CRP), ultrasound (US) (grey scale/power Doppler of 36 joints and 4 tendons) and pain catastrophizing...
August 13, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28800652/-hypothenar-hammer-syndrome-as-incidental-finding-in-hand-surgery
#5
Amir Khosrow Bigdeli, Frederick Hernekamp, Tomke Cordts, Berthold Bickert, Ulrich Kneser, Thomas Kremer
No abstract text is available yet for this article.
August 11, 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28796902/spatio-temporal-variation-in-lifelong-telomere-dynamics-in-a-long-term-ecological-study
#6
Lewis G Spurgin, Kat Bebbington, Eleanor A Fairfield, Martijn Hammers, Jan Komdeur, Terry Burke, Hannah L Dugdale, David S Richardson
Understanding individual-level variation in response to the environment is fundamental to understanding life-history evolution and population dynamics. Telomeres, the protective caps at the ends of chromosomes, shorten in response to oxidative stress, and telomere shortening is correlated with reduced survival and lifespan. Investigating telomere dynamics may help us quantify individual variation in the costs experienced from social and ecological factors, and enhance our understanding of the dynamics of natural populations...
August 10, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28794137/discrepant-measurements-of-maximal-left-ventricular-wall-thickness-between-cardiac-magnetic-resonance-imaging-and-echocardiography-in-patients-with-hypertrophic-cardiomyopathy
#7
Waseem Hindieh, Adaya Weissler-Snir, Helene Hammer, Arnon Adler, Harry Rakowski, Raymond H Chan
BACKGROUND: We sought to compare maximal left ventricular (LV) wall thickness (WT) measurements as obtained by routine clinical practice between echocardiography and cardiac magnetic resonance (CMR) and document causes of discrepancy. METHODS AND RESULTS: One-hundred and ninety-five patients with hypertrophic cardiomyopathy (median age, 52.8±15.1 years) who underwent echocardiography and CMR imaging within 6 months (median, 41 days; interquartile range, 16-97 days) were included...
August 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28789628/patellar-tendinopathy-in-young-elite-soccer-clinical-and-sonographical-analysis-of-a-german-elite-soccer-academy
#8
Gerrit Bode, Thorsten Hammer, N Karvouniaris, M J Feucht, L Konstantinidis, N P Südkamp, A Hirschmüller
BACKGROUND: The prevalence of patellar tendinopathy is elevated in elite soccer compared to less explosive sports. While the burden of training hours and load is comparably high in youth elite players (age < 23 years), little is known about the prevalence of patellar tendinopathy at this age. There is only little data available on the influence of age, the amount of training, the position on the field, as well as muscular strength, range of motion, or sonographical findings in this age group...
August 8, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28782816/clostridium-perfringens-necrotizing-fasciitis-with-massive-hemolysis
#9
D Eric Ewing, Richard D Hammer, Emily A Coberly
No abstract text is available yet for this article.
August 2017: Transfusion
https://www.readbyqxmd.com/read/28781126/targeting-mycobacterium-tuberculosis-sensitivity-to-thiol-stress-at-acidic-ph-kills-the-bacterium-and-potentiates-antibiotics
#10
Garry B Coulson, Benjamin K Johnson, Huiqing Zheng, Christopher J Colvin, Robert J Fillinger, Elizabeth R Haiderer, Neal D Hammer, Robert B Abramovitch
Mycobacterium tuberculosis (Mtb) must sense and adapt to immune pressures such as acidic pH during pathogenesis. The goal of this study was to isolate compounds that inhibit acidic pH resistance, thus defining virulence pathways that are vulnerable to chemotherapy. Here, we report that the compound AC2P36 selectively kills Mtb at acidic pH and potentiates the bactericidal activity of isoniazid, clofazimine, and diamide. We show that AC2P36 activity is associated with thiol stress and causes an enhanced accumulation of intracellular reactive oxygen species at acidic pH...
July 17, 2017: Cell Chemical Biology
https://www.readbyqxmd.com/read/28775371/scalable-and-transfer-free-fabrication-of-mos2-sio2-hybrid-nanophotonic-cavity-arrays-with-quality-factors-exceeding-4000
#11
Sebastian Hammer, H Moritz Mangold, Ariana E Nguyen, Dominic Martinez-Ta, Sahar Naghibi Alvillar, Ludwig Bartels, Hubert J Krenner
We report the fully-scalable fabrication of a large array of hybrid molybdenum disulfide (MoS2) - silicon dioxide (SiO2) one-dimensional, free-standing photonic-crystal cavities capable of enhancement of the MoS2 photoluminescence at the narrow cavity resonance. We demonstrate continuous tunability of the cavity resonance wavelength across the entire emission band of MoS2 simply by variation of the photonic crystal periodicity. Device fabrication started by substrate-scale growth of MoS2 using chemical vapor deposition (CVD) on non-birefringent thermal oxide on a silicon wafer; it was followed by lithographic fabrication of a photonic crystal nanocavity array on the same substrate at more than 50% yield of functional devices...
August 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28774737/the-mechanism-of-diabetic-retinopathy-pathogenesis-unifying-key-lipid-regulators-sirtuin-1-and-liver-x-receptor
#12
Sandra S Hammer, Eleni Beli, Nermin Kady, Qi Wang, Kiana Wood, Todd A Lydic, Goldis Malek, Daniel R Saban, Xiaoxin X Wang, Sugata Hazra, Moshe Levi, Julia V Busik, Maria B Grant
Diabetic retinopathy (DR) is a complication secondary to diabetes and is the number one cause of blindness among working age individuals worldwide. Despite recent therapeutic breakthroughs using pharmacotherapy, a cure for DR has yet to be realized. Several clinical trials have highlighted the vital role dyslipidemia plays in the progression of DR. Additionally, it has recently been shown that activation of Liver X receptor (LXRα/LXRβ) prevents DR in diabetic animal models. LXRs are nuclear receptors that play key roles in regulating cholesterol metabolism, fatty acid metabolism and inflammation...
August 2017: EBioMedicine
https://www.readbyqxmd.com/read/28773154/strain-wave-acquisition-by-a-fiber-optic-coherent-sensor-for-impact-monitoring
#13
Claudio Sbarufatti, Alessio Beligni, Andrea Gilioli, Maddalena Ferrario, Marco Mattarei, Mario Martinelli, Marco Giglio
A novel fiber optic sensing technology for high frequency dynamics detection is proposed in this paper, specifically tailored for structural health monitoring applications based on strain wave analysis, for both passive impact identification and active Lamb wave monitoring. The sensing solution relies on a fiber optic-based interferometric architecture associated to an innovative coherent detection scheme, which retrieves in a completely passive way the high-frequency phase information of the received optical signal...
July 13, 2017: Materials
https://www.readbyqxmd.com/read/28770199/a-classification-model-to-predict-the-rate-of-decline-of-kidney-function
#14
Ersoy Subasi, Munevver Mine Subasi, Peter L Hammer, John Roboz, Victor Anbalagan, Michael S Lipkowitz
The African American Study of Kidney Disease and Hypertension (AASK), a randomized double-blinded treatment trial, was motivated by the high rate of hypertension-related renal disease in the African-American population and the scarcity of effective therapies. This study describes a pattern-based classification approach to predict the rate of decline of kidney function using surface-enhanced laser desorption ionization/time of flight proteomic data from rapid and slow progressors classified by rate of change in glomerular filtration rate...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28767254/variability-in-mass-spectrometry-based-quantification-of-clinically-relevant-drug-transporters-and-drug-metabolizing-enzymes
#15
Christine Wegler, Fabienne Z Gaugaz, Tommy B Andersson, Jacek R Wiśniewski, Diana Busch, Christian Gröer, Stefan Oswald, Agneta Norén, Frederik Weiss, Helen S Hammer, Thomas O Joos, Oliver Poetz, Brahim Achour, Amin Rostami-Hodjegan, Evita van de Steeg, Heleen M Wortelboer, Per Artursson
Many different methods are used for mass-spectrometry-based protein quantification in pharmacokinetics and systems pharmacology. It has not been established to what extent the results from these various methods are comparable. Here, we compared six different mass spectrometry-based proteomics methods by measuring the expression of clinically relevant drug transporters and metabolizing enzymes in human liver. Mean protein concentrations were in general quantified to similar levels by methods using whole tissue lysates...
August 16, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28762721/supramolecular-corrals-on-surfaces-resulting-from-aromatic-interactions-of-nonplanar-triazoles
#16
Siddharth J Jethwa, Esben L Kolsbjerg, Sundar R Vadapoo, Jacob L Cramer, Lutz Lammich, Kurt V Gothelf, Bjørk Hammer, Trolle R Linderoth
Interaction forces between aromatic moieties, often referred to as π-π interactions, are an important element in stabilizing complex supramolecular structures. For supramolecular self-assembly occurring on surfaces, where aromatic moieties are typically forced to adsorb coplanar with the surface, the possible role of intermolecular aromatic interactions is much less explored. Here, we report on unusual, ring-shaped supramolecular corral surface structures resulting from adsorption of a molecule with nonplanar structure, allowing for intermolecular aromatic interactions...
August 1, 2017: ACS Nano
https://www.readbyqxmd.com/read/28760001/association-of-obesity-with-healthcare-utilization-and-costs-in-a-medicare-population
#17
Brandon T Suehs, Pravin Kamble, Joanna Huang, Mette Hammer, Jonathan Bouchard, Mary E Costantino, Andrew Renda
OBJECTIVES: To examine the association of obesity on healthcare resource utilization and costs in a Medicare population. METHODS: This study was a retrospective cohort study using Humana Medicare Advantage (MA) claims data. Body mass index (BMI) was assessed using ICD-9-CM status codes (V85 hierarchy) that have been validated in the data source to classify patients into BMI categories: Normal (N), Overweight (Ow), Obese class I (ObI), Obese class II (ObII), and Obese class III (ObIII)...
August 1, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28755934/fate-of-listeria-innocua-during-production-and-ripening-of-smeared-hard-cheese-made-from-raw-milk
#18
P Hammer, W Bockelmann, W Hoffmann
The fate of 2 different Listeria innocua strains was analyzed during the production and ripening of smeared raw milk Greyerzer cheese (Gruyère). These strains were used as surrogates for the pathogenic Listeria monocytogenes, as they are physiologically very similar. Bacterial cells were added to the cheese milk at levels of 10(5) cfu/mL. During the first 24 h of cheese making, the number of the test strains decreased to a level of below 10(2) cfu/g. Obviously, the cooking temperature of 56°C and the subsequent slight temperature decrease to 50°C within 70 min contributed to a distinct reduction of Listeria counts...
July 26, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28753846/the-landscape-of-whole-genome-alterations-and-pathologic-features-in-genitourinary-malignancies-an-analysis-of-the-cancer-genome-atlas
#19
Mark W Ball, Michael A Gorin, Charles G Drake, Hans J Hammers, Mohamad E Allaf
BACKGROUND: The accumulation of somatic genetic alterations drives carcinogenesis. Little is known, however, about how the level of genetic alteration across an entire cancer genome affects tumor grade, stage or survival. OBJECTIVE: To investigate the influence of somatic mutation count (MC) and copy number variation (CNV) on pathologic and oncologic outcomes in patients with genitourinary malignancies in The Cancer Genome Atlas (TCGA). DESIGN, SETTING, AND PARTICIPANTS: TCGA data sets for adrenocortical carcinoma (ACC), bladder urothelial carcinoma (BLCA), chromophobe renal cell carcinoma (RCC; KICH), clear cell RCC (KIRC), papillary RCC (KIRP), pheochromocytoma and paraganglioma (PCPG), prostate adenocarcinoma (PRAD), and testis germ cell tumor (TGCT) were accessed via cBioportal...
February 8, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28753548/assessment-of-strain-and-dyssynchrony-in-normal-fetuses-using-speckle-tracking-echocardiography-comparison-of-three-different-ultrasound-probes
#20
Daniel Rolf, Rene Schmidt, Mareike Möllers, Kathrin Oelmeier de Murcia, Janina Braun, Kerstin Hammer, Walter Klockenbusch, Ralf Schmitz
OBJECTIVE: To evaluate segmental left (LV-S) and right (RV-S) ventricular strain as well as longitudinal mechanical myocardial dyssynchrony as a time difference between peaks in strain of both ventricles in fetuses (two-chamber-dyssynchrony, 2C-DYS) using speckle tracking echocardiography (STE). The aim of our study was to evaluate the influence of data acquisition on the results of STE measurement using different ultrasound probes. METHODS: We prospectively recorded cardiac cycles of four-chamber views of 56 normal fetuses with three different ultrasound probes and analyzed them offline with speckle tracking imaging software...
July 28, 2017: Journal of Perinatal Medicine
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