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https://www.readbyqxmd.com/read/28220995/development-of-hydrogels-for-regenerative-engineering
#1
REVIEW
Xiaofei Guan, Meltem Avci-Adali, Emine Alarçin, Hao Cheng, Sara Saheb Kashaf, Yuxiao Li, Aditya Chawla, Hae Lin Jang, Ali Khademhosseini
The aim of regenerative engineering is to restore complex tissues and biological systems through convergence in the fields of advanced biomaterials, stem cell science, and developmental biology. Hydrogels are one of the most attractive biomaterials for regenerative engineering, since they can be engineered into tissue mimetic 3D scaffolds to support cell growth due to their similarity to native extracellular matrix. Advanced nano- and micro-technologies have dramatically increased the ability to control properties and functionalities of hydrogel materials by facilitating biomimetic fabrication of more sophisticated compositions and architectures, thus extending our understanding of cell-matrix interactions at the nanoscale...
February 21, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28218485/mechanically-milled-irregular-zinc-nanoparticles-for-printable-bioresorbable-electronics
#2
Bikram K Mahajan, Xiaowei Yu, Wan Shou, Heng Pan, Xian Huang
Bioresorbable electronics is predominantly realized by complex and time-consuming anhydrous fabrication processes. New technology explores printable methods using inks containing micro- or nano-bioresorbable particles (e.g., Zn and Mg). However, these particles have seldom been obtained in the context of bioresorbable electronics using cheap, reliable, and effective approaches with limited study on properties essential to printable electronics. Here, irregular nanocrystalline Zn with controllable sizes and optimized electrical performance is obtained through ball milling approach using polyvinylpyrrolidone (PVP) as a process control agent to stabilize Zn particles and prevent cold welding...
February 20, 2017: Small
https://www.readbyqxmd.com/read/28216554/harnessing-nanoparticles-for-immunomodulation-and-vaccines
#3
REVIEW
Ariane C Gomes, Mona Mohsen, Martin F Bachmann
The first successful use of nanoparticles (NPs) for vaccination was reported almost 40 years ago with a virus-like particle-based vaccine against Hepatitis B. Since then, the term NP has been expanded to accommodate a large number of novel nano-sized particles engineered from a range of materials. The great interest in NPs is likely not only a result of the two successful vaccines against hepatitis B and Human Papilloma Virus (HPV) that use this technology, but also due to the versatility of those small-sized particles, as indicated by the wide range of applications reported so far, ranging from medicinal and cosmetics to purely technical applications...
February 14, 2017: Vaccines
https://www.readbyqxmd.com/read/28215159/the-potential-roles-of-radionanomedicine-and-radioexosomic-in-prostate-cancer-research-and-treatment
#4
Martin K Bakht, So Won Oh, Do Won Hwang, Yun-Sang Lee, Hyewon Youn, Lisa A Porter, Gi Jeong Cheon, Cheol Kwak, Dong Soo Lee, Keon Wook Kang
The artificial nanostructures such as nanoparticles and natural nanostructures such as secreted nano-sized extracellular vesicles known as exosomes are promising tools for the realization of personalized medicine. Radionanomedicine is a recently coined term for the simultaneous application of either radiation technology or nuclear medicine with nanomedicine. In addition, radioexosomics is our suggested term for the study of exosomes functions, cytotoxicity, cancerogenicity, and biodistribution using radiation technology and nuclear medicine tracing technology...
February 16, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28213256/carbon-polydimethylsiloxane-based-integratable-optical-technology-for-spectroscopic-analysis
#5
Hiroaki Nomada, Kinichi Morita, Hirokazu Higuchi, Hiroaki Yoshioka, Yuji Oki
A polydimethylsiloxane (PDMS)-based optical system has been demonstrated. To suppress intense background radiation due to multiple internal scatting in a transparent material, a composite structure of a carbon-PDMS compound and PDMS was proposed. The index matching of the real part of the refractive index can suppress internal scattering, and an absorption of 99-99.7% was attained by using carbon micro particles and carbon nano tubes. The black-PDMS light channel functions as a light filter for straight pass, and an optical density of 5 was obtained by bending the filter...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28210947/nano-formulation-enhances-insecticidal-activity-of-natural-pyrethrins-against-aphis-gossypii-hemiptera-aphididae-and-retains-their-harmless-effect-to-non-target-predators
#6
Nikos E Papanikolaou, Argyro Kalaitzaki, Filitsa Karamaouna, Antonios Michaelakis, Vassiliki Papadimitriou, Vassilis Dourtoglou, Dimitrios P Papachristos
The insecticidal activity of a new nano-formulated natural pyrethrin was examined on the cotton aphid, Aphis gossypii Glover (Hemiptera: Aphididae), and the predators Coccinella septempunctata L. (Coleoptera: Coccinellidae) and Macrolophus pygmaeus Rambur (Hemiptera: Miridae), in respect with the nano-scale potential to create more effective and environmentally responsible pesticides. Pyrethrin was nano-formulated in two water-in-oil micro-emulsions based on safe biocompatible materials, i.e., lemon oil terpenes as dispersant, polysorbates as stabilizers, and mixtures of water with glycerol as the dispersed aqueous phase...
February 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28208094/a-simple-strategy-to-refine-cu2o-photocatalytic-capacity-for-refractory-pollutants-removal-roles-of-oxygen-reduction-and-fe-ii-chemistry
#7
Ai-Yong Zhang, Yuan-Yi He, Tan Lin, Nai-Hui Huang, Qiao Xu, Jing-Wei Feng
Visible-light-driven photocatalysis is a promising technology for advanced water treatment, but it usually exhibits a low efficiency. Cu2O is a low-cost semiconductor with narrow band gap, high absorption coefficient and suitable conduction band, but suffers from low charge mobility, poor quantum yield and weak catalytic performance. Herein, the Cu2O catalytic capacity for refractory pollutants degradation is drastically improved by a simple and effective strategy. By virtue of the synergistic effects between photocatalysis and Fenton, a novel and efficient photocatalysis-driven Fenton system, PFC, is originally proposed and experimentally validated using Cu2O/Nano-C hybrids...
January 29, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28205510/controlling-second-harmonic-generation-at-the-nanoscale-with-monolithic-algaas-on-alox-antennas
#8
L Carletti, D Rocco, A Locatelli, C De Angelis, V F Gili, M Ravaro, I Favero, G Leo, M Finazzi, L Ghirardini, M Celebrano, G Marino, A V Zayats
We review recent achievements in the field of nanoscale nonlinear AlGaAs photonics based on all-dielectric optical antennas. After discussing the motivation and main technological challenges for the development of an AlGaAs monolithic platform for χ ((2)) nonlinear nanophotonics, we present numerical and experimental investigations of the second-order nonlinear response and physical reasons for high efficiency of second-order nonlinear interactions in the AlGaAs nano-antennas. In particular, we emphasize the role of the dipolar resonances at the fundamental frequency and the multipolar resonances at the second harmonic wavelength...
February 16, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28195226/controlled-growth-of-hexagonal-gold-nanostructures-during-thermally-induced-self-assembling-on-ge-001-surface
#9
B R Jany, N Gauquelin, T Willhammar, M Nikiel, K H W van den Bos, A Janas, K Szajna, J Verbeeck, S Van Aert, G Van Tendeloo, F Krok
Nano-sized gold has become an important material in various fields of science and technology, where control over the size and crystallography is desired to tailor the functionality. Gold crystallizes in the face-centered cubic (fcc) phase, and its hexagonal closed packed (hcp) structure is a very unusual and rare phase. Stable Au hcp phase has been reported to form in nanoparticles at the tips of some Ge nanowires. It has also recently been synthesized in the form of thin graphene-supported sheets which are unstable under electron beam irradiation...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28195202/application-of-pristine-and-doped-sno2-nanoparticles-as-a-matrix-for-agro-hazardous-material-organophosphate-detection
#10
Naushad Khan, Taimur Athar, H Fouad, Ahmad Umar, Z A Ansari, S G Ansari
With an increasing focus on applied research, series of single/composite materials are being investigated for device development to detect several hazardous, dangerous, and toxic molecules. Here, we report a preliminary attempt of an electrochemical sensor fabricated using pristine Ni and Cr-doped nano tin oxide material (SnO2) as a tool to detect agro-hazardous material, i.e. Organophosphate (OP, chlorpyrifos). The nanomaterial was synthesized using the solution method. Nickel and chromium were used as dopant during synthesis...
February 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28194987/mass-defect-based-n-n-dimethyl-leucine-labels-for-quantitative-proteomics-and-amine-metabolomics-of-pancreatic-cancer-cells
#11
Ling Hao, Jillian Johnson, Christopher B Lietz, Amanda Buchberger, Dustin Frost, W John Kao, Lingjun Li
Mass spectrometry-based stable isotope labeling has become a key technology for protein and small-molecule analyses. We developed a multiplexed quantification method for simultaneous proteomics and amine metabolomics analyses via nano reversed-phase liquid chromatography-tandem mass spectrometry (nanoRPLC-MS/MS), called mass defect-based N,N-dimethyl leucine (mdDiLeu) labeling. The duplex mdDiLeu reagents were custom-synthesized with a mass difference of 20.5 mDa, arising from the subtle variation in nuclear binding energy between the two DiLeu isotopologues...
January 17, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28193541/a-nano-scaled-and-multi-layered-recombinant-fibronectin-cadherin-chimera-composite-selectively-concentrates-osteogenesis-related-cells-and-factors-to-aid-bone-repair
#12
Junchao Xing, Tieniu Mei, Keyu Luo, Zhiqiang Li, Aijun Yang, Zhilin Li, Zhao Xie, Zehua Zhang, Shiwu Dong, Tianyong Hou, Jianzhong Xu, Fei Luo
: Easily accessible and effective bone grafts are in urgent need in clinic. The selective cell retention (SCR) strategy, by which osteogenesis-related cells and factors are enriched from bone marrow into bio-scaffolds, holds great promise. However, the retention efficacy is limited by the relatively low densities of osteogenesis-related cells and factors in marrow; in addition, a lack of satisfactory surface modifiers for scaffolds further exacerbates the dilemma. To address this issue, a multi-layered construct consisting of a recombinant fibronectin/cadherin chimera was established via a layer-by-layer self-assembly technique (LBL-rFN/CDH) and used to modify demineralised bone matrix (DBM) scaffolds...
February 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28186773/real-time-measurement-of-nanotube-resonator-fluctuations-in-an-electron-microscope
#13
I Tsioutsios, A Tavernarakis, J Osmond, P Verlot, A Bachtold
Mechanical resonators based on low-dimensional materials provide a unique platform for exploring a broad range of physical phenomena. The mechanical vibrational states are indeed extremely sensitive to charges, spins, photons, and adsorbed masses. However, the roadblock is often the readout of the resonator, because the detection of the vibrational states becomes increasingly difficult for smaller resonators. Here, we report an unprecedentedly sensitive method to detect nanotube resonators with effective masses in the 10(-20) kg range...
February 17, 2017: Nano Letters
https://www.readbyqxmd.com/read/28186367/localized-synthesis-of-iron-oxide-nanowires-and-fabrication-of-high-performance-nanosensors-based-on-a-single-fe2-o3-nanowire
#14
O Lupan, V Postica, N Wolff, O Polonskyi, V Duppel, V Kaidas, E Lazari, N Ababii, F Faupel, L Kienle, R Adelung
A composed morphology of iron oxide microstructures covered with very thin nanowires (NWs) with diameter of 15-50 nm has been presented. By oxidizing metallic Fe microparticles at 255 °C for 12 and 24 h, dense iron oxide NW networks bridging prepatterned Au/Cr pads are obtained. X-ray photoelectron spectroscopy studies reveal formation of α-Fe2 O3 and Fe3 O4 on the surface and it is confirmed by detailed high-resolution transmission electron microscopy and selected area electron diffraction (SAED) investigations that NWs are single phase α-Fe2 O3 and some domains of single phase Fe3 O4 ...
February 10, 2017: Small
https://www.readbyqxmd.com/read/28186118/dynamic-in-situ-sensing-of-fluid-dispersed-2d-materials-integrated-on-microfluidic-si-chip
#15
Benjamin T Hogan, Sergey A Dyakov, Lorcan J Brennan, Salma Younesy, Tatiana S Perova, Yurii K Gun'ko, Monica F Craciun, Anna Baldycheva
In this work, we propose a novel approach for wafer-scale integration of 2D materials on CMOS photonic chip utilising methods of synthetic chemistry and microfluidics technology. We have successfully demonstrated that this approach can be used for integration of any fluid-dispersed 2D nano-objects on silicon-on-insulator photonics platform. We demonstrate for the first time that the design of an optofluidic waveguide system can be optimised to enable simultaneous in-situ Raman spectroscopy monitoring of 2D dispersed flakes during the device operation...
February 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28182433/vertical-substrate-mpcvd-epitaxial-nano-diamond-growth
#16
Yan-Kai Tzeng, Jingyuan Linda Zhang, Haiyu Lu, Hitoshi Ishiwata, Jeremy Dahl, Robert M K Carlson, Hao Yan, Peter R Schreiner, Jelena Vuckovic, Zhi-Xun Shen, Nicholas A Melosh, Steven Chu
Color center-containing nanodiamonds have many applications in quantum technologies and biology. Diamondoids, molecular-sized diamonds have been used as seeds in Chemical Vapor Deposition (CVD) growth. However, optimizing growth conditions to produce high crystal quality nanodiamonds with color centers requires varying growth conditions that often leads to ad-hoc and time-consuming, one-at-a-time testing of reaction conditions. In order to rapidly explore parameter space, we developed a microwave plasma CVD technique using a vertical, rather than horizontally oriented stage-substrate geometry...
February 9, 2017: Nano Letters
https://www.readbyqxmd.com/read/28177603/pro-inflammatory-and-pro-fibrogenic-effects-of-ionic-and-particulate-arsenide-and-indium-containing-semiconductor-materials-in-the-murine-lung
#17
Wen Jiang, Xiang Wang, Olivia J Osborne, Yingjie Du, Chong Hyun Chang, Yu-Pei Liao, Bingbing Sun, Jinhong Jiang, Zhaoxia Ji, Ruibin Li, Xiangsheng Liu, Jianqin Lu, Sijie Lin, Huan Meng, Tian Xia, André E Nel
We have recently shown that the toxicological potential of GaAs and InAs particulates in cells is size- and dissolution-dependent, tending to be more pronounced for nano- vs micron-sized particles. Whether the size-dependent dissolution and shedding of ionic III-V materials also apply to pulmonary exposure is unclear. While it has been demonstrated that micron-sized III-V particles, such as GaAs and InAs, are capable of inducing hazardous pulmonary effects in an occupational setting as well as in animal studies, the effect of submicron particles (e...
February 8, 2017: ACS Nano
https://www.readbyqxmd.com/read/28166440/malaria-treatment-using-novel-nano-based-drug-delivery-systems
#18
Uday Krishna Baruah, Kuppusamy Gowthamarajan, Ravisankar Vanka, Veera Venkata Satyanarayana Reddy Karri, Kousalya Selvaraj, Gifty M Jojo
We reside in an era of technological innovation and advancement despite which infectious diseases like malaria remain to be one of the greatest threats to the humans. Mortality rate caused by malaria disease is a huge concern in the 21(st) century. Multiple drug resistance and non-specific drug targeting of the most widely used drugs are the main reasons/drawbacks behind the failure in malarial therapy. Dose related toxicity because of high doses is also a major concern. Therefore, to overcome these problems nano based drug delivery systems are being developed to facilitate site specific or target based drug delivery and hence minimising the development of resistance progress and dose dependent toxicity issues...
February 6, 2017: Journal of Drug Targeting
https://www.readbyqxmd.com/read/28159519/intracellular-responsive-dual-delivery-by-endosomolytic-polyplexes-carrying-dna-anchored-porous-silicon-nanoparticles
#19
Mohammad-Ali Shahbazi, Patrick Vingadas Almeida, Alexandra Correia, Barbara Herranz-Blanco, Neha Shrestha, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Hélder A Santos
Bioresponsive cytosolic nanobased multidelivery has been emerging as an enormously challenging novel concept due to the intrinsic protective barriers of the cells and hardly controllable performances of nanomaterials. Here, we present a new paradigm to advance nano-in-nano integration technology amenable to create multifunctional nanovehicles showing considerable promise to overcome restrictions of intracellular delivery, solve impediments of endosomal localization and aid effectual tracking of nanoparticles...
February 1, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28159255/amorphous-nano-curcumin-stabilized-oil-in-water-emulsion-physico-chemical-characterization
#20
N P Aditya, Ian E Hamilton, Ian T Norton
Particle characteristics e.g. size and polymorphism are known to significantly affect the Pickering ability of the solid particles by influencing their interaction at the oil and water (O/W) interface. In this study, nano-sized amorphous curcumin particles were fabricated using nanonization technology to use them as Pickering particles. After nanonization, native crystalline curcumin particles were converted into amorphous, nanosized particles of ∼220nm. Amorphous nature of the particle was evident from the decreased melting point from 177±1°C (native curcumin) to 146±3°C (nanonized curcumin) and enthalpy from 27±2J/g to 3...
June 1, 2017: Food Chemistry
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