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https://www.readbyqxmd.com/read/28936174/the-effect-of-velvet-antler-proteins-on-cardiac-microvascular-endothelial-cells-challenged-with-ischemia-hypoxia
#1
Xiang Xiao, Shuqiang Xu, Lin Li, Min Mao, Jinping Wang, Yanjun Li, Ziwei Wang, Fei Ye, Li Huang
Velvet antler (VA) is a precious traditional Chinese medicine that is capable of repeated regeneration. Based on the Chinese medicine theory of coordination the heart and kidneys, VA has been employed to treat heart diseases, including ischemic heart disease, heart failure, and arrhythmia. We examined the effects of VA proteins on primary cardiac microvascular endothelial cells (CMECs) that were subjected to ischemia-hypoxia (IH) to investigate their effects on and mechanism of action in the treatment of ischemic heart disease...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28935767/hanbury-brown-and-twiss-interferometry-of-single-phonons-from-an-optomechanical-resonator
#2
Sungkun Hong, Ralf Riedinger, Igor Marinković, Andreas Wallucks, Sebastian G Hofer, Richard A Norte, Markus Aspelmeyer, Simon Gröblacher
Nano- and micromechanical devices have become a focus of attention as new solid-state quantum devices. Reliably generating non-classical states of their motion is of interest both for addressing fundamental questions about macroscopic quantum phenomena as well as for developing quantum technologies in the domains of sensing and transduction. We use quantum optical control techniques to conditionally generate single-phonon Fock states of a nanomechanical resonator. We perform a Hanbury Brown and Twiss type experiment that verifies the non-classical nature of the phonon state without requiring full state reconstruction...
September 21, 2017: Science
https://www.readbyqxmd.com/read/28933269/drug-delivery-and-cosmeceutical-applications-of-polylactic-acid-based-novel-constructs-a-review
#3
Hafiz M N Iqbal, Federico Ruiz-Ruiz, Elena Ivonne Mancera-Andrade, Roberto Parra-Saldivar, Tajalli Keshavarz
In recent years, there has been a great research interest in bio-based biopolymers due to their potential as alternative polymers to the traditional petroleum-based synthetic counterparts. Research is underway around the globe on the development of 'greener' technologies. Recently, bio-based bio-constructs are being engineered for target applications in different bio- and non-bio sectors of the modern world to address growing concerns of a global dependence on non-renewable petroleum-based resources. The utilization of properly designed and structured materials thus allows for the creation of well-defined environment that induces a series of directed measures, and so on...
September 19, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28932831/smart-supramolecular-sensing-with-cucurbit-n-urils-probing-hydrogen-bonding-with-sers
#4
Bart de Nijs, Marlous Kamp, Istvan Szabó, Steven J Barrow, Felix Benz, Guanglu Wu, Cloudy Carnegie, Rohit Chikkaraddy, Wenting Wang, William M Deacon, Edina Rosta, Jeremy J Baumberg, Oren A Scherman
Rigid gap nano-aggregates of Au nanoparticles formed using cucurbit[n]uril (CB[n]) molecules are used to investigate the competitive binding of ethanol and methanol in an aqueous environment. We show it is possible to detect as little as 0.1% methanol in water and a ten times higher affinity to methanol over ethanol, making this a useful technology for quality control in alcohol production. We demonstrate strong interaction effects in the SERS peaks, which we demonstrate are likely from the hydrogen bonding of water complexes in the vicinity of the CB[n]s...
September 21, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28931872/efficient-steam-generation-by-inexpensive-narrow-gap-evaporation-device-for-solar-applications
#5
Matteo Morciano, Matteo Fasano, Uktam Salomov, Luigi Ventola, Eliodoro Chiavazzo, Pietro Asinari
Technologies for solar steam generation with high performance can help solving critical societal issues such as water desalination or sterilization, especially in developing countries. Very recently, we have witnessed a rapidly growing interest in the scientific community proposing sunlight absorbers for direct conversion of liquid water into steam. While those solutions can possibly be of interest from the perspective of the involved novel materials, in this study we intend to demonstrate that efficient steam generation by solar source is mainly due to a combination of efficient solar absorption, capillary water feeding and narrow gap evaporation process, which can also be achieved through common materials...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931430/global-proteomic-profiling-of-yersinia-ruckeri-strains
#6
Gokhlesh Kumar, Karin Hummel, Timothy J Welch, Ebrahim Razzazi-Fazeli, Mansour El-Matbouli
Yersinia ruckeri is the causative agent of enteric redmouth disease (ERM) of salmonids. There is little information regarding the proteomics of Y. ruckeri. Herein, we perform whole protein identification and quantification of biotype 1 and biotype 2 strains of Y. ruckeri grown under standard culture conditions using a shotgun proteomic approach. Proteins were extracted, digested and peptides were separated by a nano liquid chromatography system and analyzed with a high-resolution hybrid triple quadrupole time of flight mass spectrometer coupled via a nano ESI interface...
September 20, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28926948/field-emission-from-self-catalyzed-gaas-nanowires
#7
Filippo Giubileo, Antonio Di Bartolomeo, Laura Iemmo, Giuseppe Luongo, Maurizio Passacantando, Eero Koivusalo, Teemu V Hakkarainen, Mircea Guina
We report observations of field emission from self-catalyzed GaAs nanowires grown on Si (111). The measurements were taken inside a scanning electron microscope chamber with a nano-controlled tungsten tip functioning as anode. Experimental data were analyzed in the framework of the Fowler-Nordheim theory. We demonstrate stable current up to 10(-7) A emitted from the tip of single nanowire, with a field enhancement factor β of up to 112 at anode-cathode distance d = 350 nm. A linear dependence of β on the anode-cathode distance was found...
September 16, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28926707/medieval-gilding-technology-of-historical-metal-threads-revealed-by-electron-optical-and-micro-raman-spectroscopic-study-of-focused-ion-beam-milled-cross-sections
#8
Tamás Gábor Weiszburg, Katalin Gherdán, Kitti Ratter, Norbert Zajzon, Zsolt Bendő, György Z Radnoczi, Ágnes Takács, Tamás Váczi, Gábor Varga, György Szakmány
Although gilt silver threads were widely used for decorating historical textiles, their manufacturing techniques have been elusive for centuries. Contemporary written sources give only limited, sometimes ambiguous information, and detailed cross-sectional study of the microscale soft noble metal objects has been hindered by sample preparation. In this work, to give a thorough characterization of historical gilt silver threads, nano- and microscale textural, chemical and structural data on cross sections, prepared by focused ion beam milling, were collected, using various electron-optical methods (high-resolution scanning electron microscopy (SEM), wavelength-dispersive electron probe microanalysis (EPMA), electron back-scattered diffraction (EBSD) combined with energy-dispersive electron probe microanalysis (EDX), transmission electron microscopy (TEM) combined with EDX, and micro-Raman spectroscopy...
September 19, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28926262/effect-of-the-incorporation-of-nano-sized-titanium-dioxide-on-the-interfacial-properties-of-dppc-langmuir-monolayers
#9
Eduardo Guzmán, Eva Santini, Michele Ferrari, Libero Liggieri, Francesca Ravera
The effect of the incorporation of hydrophilic titanium dioxide (TiO2) nanoparticles on the interfacial properties of Langmuir monolayers of 1,2-Dipalmitoyl-sn-glycerol-3-phosphocholine (DPPC) has been evaluated combining interfacial thermodynamic studies, dilatational rheology and Brewster Angle Microscopy (BAM). The results show that the TiO2 nanoparticles are able to penetrate into DPPC layers, modifying the organization of the molecules and, consequently, the phase behaviour and viscoelastic properties of the systems...
September 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28924257/electrodiffusion-phenomena-in-neuroscience-a-neglected-companion
#10
REVIEW
Leonid P Savtchenko, Mu Ming Poo, Dmitri A Rusakov
The emerging technological revolution in genetically encoded molecular sensors and super-resolution imaging provides neuroscientists with a pass to the real-time nano-world. On this small scale, however, classical principles of electrophysiology do not always apply. This is in large part because the nanoscopic heterogeneities in ionic concentrations and the local electric fields associated with individual ions and their movement can no longer be ignored. Here, we review basic principles of molecular electrodiffusion in the cellular environment of organized brain tissue...
September 19, 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/28920496/spin-rapid-synthesis-purification-and-concentration-of-small-drug-loaded-liposomes
#11
Steven A Roberts, Neil Parikh, Ryan J Blower, Nitin Agrawal
Liposomes are one of the most studied nano-delivery systems. However, only a handful of formulations have received FDA approval. Existing liposome synthesis techniques are complex and specialized, posing a major impediment in design, implementation, and mass production of liposome delivery systems as therapeutic agents. Here, we demonstrate a unique 'synthesis and purification of injectable nanocarriers' (SPIN) technology for rapid and efficient production of small drug loaded liposomes using common benchtop equipment...
September 18, 2017: Journal of Liposome Research
https://www.readbyqxmd.com/read/28920126/high-energy-product-chemically-synthesized-exchange-coupled-nd2fe14b-%C3%AE-fe-magnetic-powders
#12
Harshida Parmar, T Xiao, V Chaudhary, Y Zhong, R V Ramanujan
The excellent hard magnetic properties of Nd2Fe14B based magnets have an enormous range of technological applications. Exchange-coupled Nd2Fe14B/α-Fe magnets were chemically synthesized by a microwave assisted combustion process to produce mixed oxides, followed by a reduction diffusion process to form magnetic nano-composite powder. This synthesis technique offers an inexpensive and facile platform to produce exchange coupled hard magnets. The size dependent magnetic properties were investigated. The formation mechanisms of the oxide powders and the reduction diffusion mechanism were identified...
September 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28920009/raman-under-water-nonlinear-and-nearfield-approaches-for-electrochemical-surface-science
#13
REVIEW
Natalia Martín Sabanés, Katrin F Domke
Electrochemistry is re-gaining attention among scientists because the complex interplay between electronic and chemical interfacial processes lies at the bottom of a broad range of important research disciplines like alternative energy conversion or green catalysis and synthesis. While rapid progress has been made in recent years regarding novel technological applications, the community increasingly recognizes that the understanding of the molecular processes that govern macroscopic device properties is still rather limited - which hinders a systematic and more complete exploration of novel material and functionality space...
August 2017: ChemElectroChem
https://www.readbyqxmd.com/read/28918292/nanoscaled-gold-and-silver-simultaneous-removal-and-transformation-to-functional-materials
#14
Youyi Xia, Lin Sun, Hongping Xiao
Based on an "acid-assisted cool welding" technology which was realized by virtue of the freezing process in the presence of acid, nanoscaled gold (Au) and silver (Ag) from wastewater could be removed very facilely and efficiently. The technology was independence of the freezing temperature, size as well as shape of those nanoscaled units. Besides, some functional materials like porous nanostructures with highly and stably catalytic activity could be also obtained during the removal. Our research not only provided a new method to remove nanoscaled Ag or Au from wastewater, but also built up a unique route to transform those nano-units into functional materials simultaneously...
September 9, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28917964/phenazopyridine-phthalimide-nano-cocrystal-release-rate-and-oral-bioavailability-enhancement
#15
Yu Huang, Jin-Mei Li, Zhi-Hui Lai, Jun Wu, Tong-Bu Lu, Jia-Mei Chen
Both cocrystal and nanocrystal technologies have been widely used in the pharmaceutical development for poorly soluble drugs. However, the synergistic effects due to the integration of these two technologies have not been well investigated. The aim of this study is to develop a nano-sized cocrystal of phenazopyridine (PAP) with phthalimide (PI) to enhance the release rate and oral bioavailability of PAP. A PAP-PI nano-cocrystal with particle diameter of 21.4±0.1nm was successfully prepared via a sonochemical approach and characterized by powder X-ray diffraction (PXRD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and dynamic light scattering (DLS) analysis...
September 14, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28916111/icosahedral-plant-viral-nanoparticles-bioinspired-synthesis-of-nanomaterials-nanostructures
#16
REVIEW
Kannan Badri Narayanan, Sung Soo Han
Viral nanotechnology utilizes virus nanoparticles (VNPs) and virus-like nanoparticles (VLPs) of plant viruses as highly versatile platforms for materials synthesis and molecular entrapment that can be used in the nanotechnological fields, such as in next-generation nanoelectronics, nanocatalysis, biosensing and optics, and biomedical applications, such as for targeting, therapeutic delivery, and non-invasive in vivo imaging with high specificity and selectivity. In particular, plant virus capsids provide biotemplates for the production of novel nanostructured materials with organic/inorganic moieties incorporated in a very precise and controlled manner...
August 31, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28914766/development-of-a-sensitive-electrochemical-enzymatic-reaction-based-cholesterol-biosensor-using-nano-sized-carbon-interdigitated-electrodes-decorated-with-gold-nanoparticles
#17
Deepti Sharma, Jongmin Lee, Junyoung Seo, Heungjoo Shin
We developed a versatile and highly sensitive biosensor platform. The platform is based on electrochemical-enzymatic redox cycling induced by selective enzyme immobilization on nano-sized carbon interdigitated electrodes (IDEs) decorated with gold nanoparticles (AuNPs). Without resorting to sophisticated nanofabrication technologies, we used batch wafer-level carbon microelectromechanical systems (C-MEMS) processes to fabricate 3D carbon IDEs reproducibly, simply, and cost effectively. In addition, AuNPs were selectively electrodeposited on specific carbon nanoelectrodes; the high surface-to-volume ratio and fast electron transfer ability of AuNPs enhanced the electrochemical signal across these carbon IDEs...
September 15, 2017: Sensors
https://www.readbyqxmd.com/read/28914524/templated-and-catalytic-fabrication-of-n-doped-hierarchical-porous-carbon-carbon-nanotubes-hybrids-as-host-for-lithium-sulfur-batteries
#18
Junjie Cai, Chun Wu, Shaoran Yang, Ying Zhu, Pei Kang Shen, Kaili Zhang
Nitrogen-doped hierarchical porous carbon and carbon nanotube hybrids (N-HPC-CNTs) are fabricated by simple pyrolysis of the N-rich raw material melamine-formaldehyde (MF) resin in the presence of nano-CaCO3 and bimetallic combination of Fe-Co catalyst. During carbonization, nano-CaCO3 acts as template for creating a hierarchical porous carbon and the N atoms originated from MF resin are in-situ doped into the carbon matrix simultaneously. Meanwhile, volatile gases generated by the thermal decomposition of MF resin could serve as carbon and nitrogen sources to grow nitrogen doped CNTs on HPC...
September 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28913525/formation-of-antireflection-zn-zno-core-shell-nano-pyramidal-arrays-by-o2-ion-bombardment-of-zn-surfaces
#19
Noelia Benito, Gonzalo Recio-Sánchez, Ramón Escobar-Galindo, Carlos Palacio
ZnO is probably one of the most studied oxides since ZnO nanostructures are a very rich family of nanomaterials with a broad variety of technological applications. Although several chemical techniques offer the possibility to obtain such ZnO nanostructures, here we show that the controlled modification of the zinc surface by low-energy O2(+) bombardment leads to the formation of core-shell Zn/ZnO nano-pyramidal arrays that suppress the reflection of light decreasing the reflectivity below 6% in the wavelength range of 300-900 nm...
September 15, 2017: Nanoscale
https://www.readbyqxmd.com/read/28901806/optimised-selenium-enrichment-of-artemia-sp-feed-to-improve-red-drum-sciaenops-ocellatus-larvae-rearing
#20
Péter Juhász, Szvetlana Lengyel, Zsolt Udvari, Alex Nagy Sándor, László Stündl
Selenium is an essential microelement for the normal functioning of life processes. Moreover, it is a component of enzymes with antioxidant effects. However, it has the smallest window of any micronutrient between requirement and toxicity. Selenium is a regularly used element in fish feeds; moreover, enriching zooplankton with selenium to rear larvae is also a well-known technology. It is accepted that the most common starter foods of fish larvae, natural rotifers contain the smallest dosage of selenium, but providing selenium enriched Artemia sp...
September 2017: Acta Biologica Hungarica
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