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https://www.readbyqxmd.com/read/29223730/characterization-of-a-new-decellularized-bovine-pericardial-biological-mesh-structural-and-mechanical-properties
#1
Alessandra Bielli, Roberta Bernardini, Dimitrios Varvaras, Piero Rossi, Giancarlo Di Blasi, Giuseppe Petrella, Oreste Claudio Buonomo, Maurizio Mattei, Augusto Orlandi
Implants made from naturally-derived biomaterials, also called biological meshes or biomeshes, typically derive from decellularized extracellular matrix of either animal or human tissue. Biomeshes have many biomedical applications such as ligament repair, bone and cartilage regeneration and soft tissue replacement. Bovine collagen is one of the most widely used and abundantly available xenogenic materials. In particular, bovine pericardium is widely used as extracellular matrix bioprosthetic tissue. The efficiency of a pericardial mesh to function as scaffold depends on the quality of the decellularization protocol used...
December 5, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29223703/the-foreign-body-response-and-morphometric-changes-associated-with-mesh-style-peripheral-nerve-cuffs
#2
Michael B Christensen, Patrick A Tresco
Nerve cuffs have been used to anchor and protect penetrating electrodes in peripheral nerves and have been used as non-penetrating electrodes for neural recording and nerve stimulation. The material of choice for such applications is silicone, an inert synthetic biomaterial which elicits a minimal chronic foreign body response (FBR). While histological studies of solid silicone cuffs are available, to the best of our knowledge a comparison to other cuff designs is not well documented. Here, we describe the FBR and morphological changes that accompany nerve cuff implantation in the rat sciatic nerve by comparing a metallic mesh with and without a parylene coating to one made of silicone...
December 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29217786/transvaginal-mesh-failure-lessons-for-regulation-of-implantable-devices
#3
Carl Heneghan, Jeffrey K Aronson, Ben Goldacre, Kamal R Mahtani, Annette Plüddemann, Igho Onakpoya
No abstract text is available yet for this article.
December 7, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29215451/mandibular-reconstruction-using-a-customized-three-dimensional-titanium-implant-applied-on-the-lingual-surface-of-the-mandible
#4
You-Young Jo, Seong-Gon Kim, Min-Keun Kim, Sung-Ho Shin, Janghoon Ahn, Hyun Seok
A patient had a right mandibular defect due to resection of an ameloblastoma. Previously, the defect had been reconstructed by an iliac bone graft, and subsequently, a titanium mesh with xenograft was used. However, it was not successfully reconstructed. For the recovery of mandible continuity and rehabilitation of jaw movement, we manufactured a customized 3-dimensional titanium implant by computer-aided design and manufacturing and electron beam melting technology. This implant was designed to have a porous body structure and lingual plate...
December 6, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29214543/comparison-of-biological-and-alloplastic-meshes-in-ventral-incisional-hernia-repair
#5
A Koscielny, S Widenmayer, T May, J Kalff, P Lingohr
PURPOSE: The aim of our retrospective analysis was to compare the results of incisional hernia repair by porcine small intestinal submucosa-derived (SIS) meshes with those obtained by alloplastic polypropylene-based (PP) meshes in comparable surgical indications by matched-pair design. We hypothesized that in incisional hernia, SIS mesh repair is associated with fewer recurrences and SSO than PP mesh repair in incisional hernias. METHODS: Twenty-four matched pairs (SIS vs...
December 6, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29211118/venous-blood-derivatives-as-fbs-substitutes-for-mesenchymal-stem-cells-a-systematic-scoping-review
#6
Luiz A Chisini, Marcus C M Conde, Guillermo Grazioli, Alissa S San Martin, Rodrigo Varella de Carvalho, Jacques E Nör, Flávio F Demarco
Although the biological properties of mesenchymal stem cells (MSC) are well-characterized in vitro, MSC clinical application is still far away to be achieved, mainly due to the need of xenogeneic substances for cell expansion, such as fetal bovine serum (FBS). FBS presents risks regarding pathogens transmissions and internalization of animal's proteins, which can unleash antigenic responses in patients after MSC implantation. A wide range of venous blood derivatives (VBD) has been reported as FBS substitutes showing promising results...
November 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29205768/the-applications-of-regenerative-medicine-in-sinus-lift-procedures-a-systematic-review
#7
REVIEW
Francisco Correia, Daniel Humberto Pozza, Sónia Gouveia, António Felino, Ricardo Faria E Almeida
BACKGROUND: Findings in regenerative medicine applied to the sinus lift procedures. PURPOSE: Evaluate the effectiveness of regenerative medicine in sinus lift. MATERIALS AND METHODS: An extensive search for manuscripts were performed by using different combinations of keywords and MeSH terms (Pub-med; Embase; Scopus; Web of Science Core Collection; Medline; Current Contents Connect; Derwent Innovations Index; Scielo Citation Index; Cochrane library)...
December 3, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29202327/mesh-electronics-a-new-paradigm-for-tissue-like-brain-probes
#8
REVIEW
Guosong Hong, Xiao Yang, Tao Zhou, Charles M Lieber
Existing implantable neurotechnologies for understanding the brain and treating neurological diseases have intrinsic properties that have limited their capability to achieve chronically-stable brain interfaces with single-neuron spatiotemporal resolution. These limitations reflect what has been dichotomy between the structure and mechanical properties of living brain tissue and non-living neural probes. To bridge the gap between neural and electronic networks, we have introduced the new concept of mesh electronics probes designed with structural and mechanical properties such that the implant begins to 'look and behave' like neural tissue...
December 1, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/29201518/transobturator-four-arms-mesh-in-the-surgical-management-of-stress-urinary-incontinence-with-cystocele
#9
Hammouda Sherif, Tarek Soliman Othman, Amr Eldkhakhany, Hussein Elkady, Adel Elfallah
Objective: This study aims to evaluate safety and efficacy of four arms polypropylene mesh in the long- term follow-up in the management of stress urinary incontinence (SUI) associated with cystocele. Material and methods: This prospective study was conducted on 50 female patients with SUI associated with cystocele. Patients underwent placement of transobturator four-arms mesh implants. Stress incontinence was evaluated using cough stress test with and without prolapse reduction, Stamey's grading of SUI, the validated Arabic version of the International Consultation on Incontinence Questionnaire-Short Form and King Health Questionnaire forms...
December 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29196176/assessing-value-in-breast-reconstruction-a-systematic-review-of-cost-effectiveness-studies
#10
Clifford C Sheckter, Evan Matros, Arash Momeni
INTRODUCTION: Breast reconstruction is one of the most common procedures performed by plastic surgeons and is achieved through various choices in both technology and method. Cost-effectiveness analyses are increasingly important in assessing differences in value between treatment options, which is relevant in a world of confined resources. A thorough evaluation of the cost-effectiveness literature can assist surgeons and health systems evaluate high-value care models. METHODS: A systematic review of PubMed, Web of Science, and the Cost-Effectiveness Analysis Registry was conducted...
October 9, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29194211/publishing-trends-in-otology-and-neurotology
#11
Ryan Boerner, Jonathan L Hatch, Elizabeth Harruff, Shaun A Nguyen, Habib G Rizk, Ted A Meyer, Paul R Lambert, Theodore R McRackan
OBJECTIVES: 1) Describe publishing trends for otologic/neurotologic disorders over a 35-year span. 2) Compare trends in publishing with disease prevalence. 3) Evaluate changes in topic and journal specific ranking scores over time. METHODS: PubMed searches were performed on 35 otologic/neurotologic disorders using medical subject headings (MeSH) terms from 1980 to 2015. Searches were limited in scope to the English language. A Mann-Kendall trend analysis evaluated changes in publication frequency as a discrete variable while correcting for total number of articles published per year...
November 29, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29187125/nitro-oleic-acid-no2oa-release-enhances-regional-angiogenesis-in-a-rat-abdominal-wall-defect-model
#12
Antonio D'Amore, Marco Fazzari, Hongbin Jiang, Samuel K Luketich, Michael E Luketich, Richard F Hoff, Daniel L Jacobs, Xinzhu Gu, Stephen F Badylak, Bruce A Freeman, William R Wagner
Ventral hernia is often addressed surgically by the placement of prosthetic materials, either synthetic or from allogeneic and xenogeneic biologic sources. Despite advances in surgical approaches and device design, a number of postsurgical limitations remain, including hernia recurrence, mesh encapsulation, and reduced vascularity of the implanted volume. The in situ controlled release of angiogenic factors from a scaffold facilitating abdominal wall repair might address some of these issues associated with sub-optimal tissue reconstruction...
November 29, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29181144/evaluation-of-electrospun-nanofiber-anchored-silicone-for-the-degenerative-intervertebral-disc
#13
M Khandaker, S Riahanizad
The nucleus pulposus (NP) substitution by polymeric gel is one of the promising techniques for the repair of the degenerative intervertebral disc (IVD). Silicone gel is one of the potential candidates for a NP replacement material. Electrospun fiber anchorage to silicone disc, referred as ENAS disc, may not only improve the biomechanical performances of the gel but it can also improve restoration capability of the gel, which is unknown. This study successfully produced a novel process to anchor any size and shape of NP gel with electrospun fiber mesh...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29180195/sutures-versus-new-cyanoacrylates-in-prosthetic-abdominal-wall-repair-a-preclinical-long-term-study
#14
Gemma Pascual, Marta Rodríguez, Claudia Mesa-Ciller, Bárbara Pérez-Köhler, Mar Fernández-Gutiérrez, Julio San Román, Juan M Bellón
BACKGROUND: As an alternative to sutures, meshes used for hernia repair can be fixed using cyanoacrylate-based adhesives. Attempts to improve these adhesives include alkyl-chain lengthening to reduce their toxicity. This preclinical study compares the long-term behavior of cyanoacrylates of different chain lengths already used in hernia repair and new ones for this application. MATERIALS AND METHODS: Partial abdominal wall defects were repaired using a Surgipro mesh in 18 New Zealand White rabbits, and groups were established according to the mesh fixation method: sutures (control), Glubran 2 (n-butyl), Ifabond (n-hexyl), and the new adhesives SafetySeal (n-butyl), and Evobond (n-octyl)...
December 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29171319/cost-effectiveness-of-tyrx%C3%A2-absorbable-antibacterial-envelope-for-prevention-of-cardiovascular-implantable-electronic-device-infection
#15
Gemma Kay, Elizabeth L Eby, Benedict Brown, Julie Lyon, Simon Eggington, Gayathri Kumar, Elisabeth Fenwick, M Rizwan Sohail, David Jay Wright
AIMS: Infection is a major complication of cardiovascular implantable electronic device (CIED) therapy that usually requires device extraction and is associated with increased morbidity and mortality. The TYRX Antibacterial Envelope is a polypropylene mesh that stabilises the CIED and elutes minocycline and rifampin to reduce the risk of post-operative infection. METHODS: A decision tree was developed to assess the cost-effectiveness of TYRX versus standard of care (SOC) following implantation of four CIED device types...
November 24, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29170793/clinical-predictors-and-risk-factors-for-vaginal-mesh-extrusion
#16
Usah Khrucharoen, Patkawat Ramart, Judy Choi, Diana Kang, Ja-Hong Kim, Shlomo Raz
PURPOSES: Our study aims to enhance the accuracy of the clinical diagnosis in patients with vaginal mesh extrusion following transvaginal mesh placement for pelvic organ prolapse using significant clinical parameters and risk factors. METHODS: All patients who underwent vaginal mesh removal were retrospectively reviewed from January 2000 to May 2014. Eligible patients were divided into two groups according to the presence of vaginal mesh extrusion. RESULTS: A total of 862 patients, 798 were included...
November 24, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29166695/-without-net-and-double-floor-comparison-of-umbilical-hernia-repair-by-spitzy-in-children-and-adults
#17
Laura Kuck, Florian Seitz, Armin Wiegering, Ulrich Dietz, Thomas Meyer
Summary Umbilical hernia occur in both adults and children. For over 100 years, umbilical hernia in children has been treated surgically by the Spitzy method. With adult patients, meshes are being increasingly used. The purpose of our study was to analyse Spitzy herniotomy with respect to the recurrence rate in children and adults. Material and Methods Over a period of 7 years, 383 children (age < 16 years) with umbilical hernia were treated surgically; after applying the exclusion criteria, 370 patients were evaluated...
November 22, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29164131/continuous-laparoscopic-closure-of-the-linea-alba-with-barbed-sutures-combined-with-laparoscopic-mesh-implantation-ipom-plus-repair-as-a-new-technique-for-treatment-of-abdominal-hernias
#18
Reiko Wiessner, Thomas Vorwerk, Claudia Tolla-Jensen, Alexander Gehring
Despite extensive experience and significant reduction of complications in recent years, laparoscopic treatment of complex abdominal hernias is a challenge even for the experienced endoscopic surgeon. Patients with severe incisional hernias or symptomatic rectus diastasis benefit from the closure of the linea alba as a morphological and physiological reconstruction of the abdominal wall followed by mesh implantation. Occasionally, an additional component separation is necessary. In open surgery, this is associated with very large wound areas, postoperative seromas, poor wound healing and, in the worst case, mesh infections...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29164019/quantitative-analysis-of-electro-anatomical-maps-application-to-an-experimental-model-of-left-bundle-branch-block-cardiac-resynchronization-therapy
#19
David Soto Iglesias, Nicolas Duchateau, Constantine Butakoff Kostantyn Butakov, David Andreu, Juan Fernandez-Armenta, Bart Bijnens, Antonio Berruezo, Marta Sitges, Oscar Camara
Electro-anatomical maps (EAMs) are commonly acquired in clinical routine for guiding ablation therapies. They provide voltage and activation time information on a 3-D anatomical mesh representation, making them useful for analyzing the electrical activation patterns in specific pathologies. However, the variability between the different acquisitions and anatomies hampers the comparison between different maps. This paper presents two contributions for the analysis of electrical patterns in EAM data from biventricular surfaces of cardiac chambers...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/29159603/prophylactic-intraperitoneal-onlay-mesh-reinforcement-reduces-the-risk-of-incisional-hernia-two-year-results-of-a-randomized-clinical-trial
#20
Philippe Brosi, Philippe M Glauser, Benjamin Speich, Samuel A Käser, Christoph A Maurer
BACKGROUND: Incisional hernias still are a major concern after laparotomy and are causing substantial morbidity. This study examines the feasibility, safety and incisional hernia rate of the use of a prophylactic intraperitoneal onlay mesh stripe (IPOM) to prevent incisional hernia following midline laparotomy. METHODS: This prospective, randomized controlled trial randomly allocated patients undergoing median laparotomy either to mass closure of the abdominal wall with a PDS-loop running suture reinforced by an intraperitoneal composite mesh stripe (Group A) or to the same procedure without the additional mesh stripe (Group B)...
November 20, 2017: World Journal of Surgery
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