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https://www.readbyqxmd.com/read/28210969/host-tissue-response-by-the-expression-of-collagen-to-cyanoacrylate-adhesives-used-in-implant-fixation-for-abdominal-hernia-repair
#1
Gemma Pascual, Marta Rodríguez, Bárbara Pérez-Köhler, Claudia Mesa-Ciller, Mar Fernández-Gutiérrez, Julio San Román, Juan M Bellón
The less traumatic use of surgical adhesives rather than sutures for mesh fixation in hernia repair has started to gain popularity because they induce less host tissue damage and provoke less postoperative pain. This study examines the host tissue response to a new cyanoacrylate (CA) adhesive (n-octyl, OCA). Partial defects (3 × 5 cm) created in the rabbit anterior abdominal wall were repaired by mesh fixation using OCA, Glubran2(®)(n-butyl-CA), Ifabond(®)(n-hexyl-CA) or sutures. Samples were obtained at 14/90 days for morphology, collagens qRT-PCR/immunofluorescence and biomechanical studies...
April 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28210555/breast-reconstruction-with-absorbable-mesh-sling-dynamic-infrared-thermography-of-skin-envelope
#2
Yoko Hashimoto, Naoki Watanabe, Takeshi Yuasa, Yoshinori Suzuki, Hiroshi Saisho
BACKGROUND: To immediate reconstruct ptosis breasts, we used polyglactin (Vicryl; Ethicon Inc., Somerville, NJ, USA) mesh as an inferolateral sling. However, Vicryl mesh is absorbable and losing function as a supporting structure. We doubt about the stability of the blood supply to the inferior part of the flap when it is in direct contact with inner implant. In this study, we examine the complications and the safety of the skin flap of this absorbable mesh sling (AMS) procedure. METHODS: The outcomes of 80 cases were examined, and the 1-year safety record of 40 cases was assessed...
February 2017: Gland Surgery
https://www.readbyqxmd.com/read/28210413/orbital-adherence-syndrome-following-the-use-of-titanium-precontoured-orbital-mesh-for-the-reconstruction-of-posttraumatic-orbital-floor-defects
#3
Geraldine Hwee Ping Lee, Samuel Yew Ming Ho
Orbital blowout fractures are a common occurrence following orbital trauma. Depending on the size of the defect and the contents that have herniated or incarcerated, possible sequelae include enophthalmos, diplopia, dystopia, and entrapment. Surgical intervention aims to prevent or alleviate this through the use of a bone graft or an alloplastic implant to reconstitute the continuity of the orbit. However, in doing so, the implant itself may result in the unexpected adherence of the periorbita, resulting in orbital adherence syndrome...
March 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28192870/clinical-and-immunohistochemical-performance-of-lyophilized-platelet-rich-fibrin-ly-prf-on-tissue-regeneration
#4
Jianming Zhang, Xingying Qi, Xiaoding Luo, Dan Li, Haorong Wang, Ting Li
BACKGROUND: Platelet-rich fibrin (PRF) has been widely used in oral implantology and other fields, but benefits of the fresh PRF (FPRF (fresh platelet-rich fibrin)) were consequently limited because of its short-term application. Thus, a protocol for the combination of PRF and lyophilization comes up in the present study to address the issue of PRF storage and delayed clinical application, which has little been reported in this field at home and abroad by now. PURPOSE: The aim of the present study was to evaluate the applicability of lyophilized platelet-rich fibrin (Ly-PRF) used as the scaffold material for craniofacial tissue regeneration and to compare its biochemical properties with commonly used fresh PRF...
February 13, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28183673/attenuation-of-the-in-vitro-neurotoxicity-of-316l-ss-by-graphene-oxide-surface-coating
#5
Nishat Tasnim, Alok Kumar, Binata Joddar
A persistent theme in biomaterials research comprises of surface engineering and modification of bare metallic substrates for improved cellular response and biocompatibility. Graphene Oxide (GO), a derivative of graphene, has outstanding chemical and mechanical properties; its large surface to volume ratio, ease of surface modification and processing make GO an attractive coating material. GO-coatings have been extensively studied as biosensors. Further owing to its surface nano-architecture, GO-coated surfaces promote cell adhesion and growth, making it suitable for tissue engineering applications...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28181115/nitric-oxide-coating-polypropylene-mesh-increases-angiogenesis-and-reduces-inflammatory-response-and-apoptosis
#6
Alessandro Prudente, Wágner José Favaro, Leonardo Oliveira Reis, Cássio Luis Zanettini Riccetto
OBJECTIVES: To evaluate the effect of implanted S-nitrosoglutathione (GSNO) coating polypropylene mesh in foreign-body response of rats. METHODS: Thirty female rats underwent to subcutaneous implant of five polypropylene (PP) fragments: uncoated PP (control); PP polyvinylalcohol (PVA) coated and PP PVA + GSNO (1, 10 and 70 mMol) coated. After euthanasia (4 and 30 days), eight slides were prepared from each animal: hematoxylin-eosin (inflammatory response); unstained (birefringence collagen evaluation); TUNEL technique (apoptosis); and five for immunohistochemical processing: CD-31 (angiogenesis), IL-1 and TNF-α (proinflammatory cytokynes), iNOS (NO synthesis) and MMP-2 (collagen metabolism)...
February 8, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28170157/combining-electrospinning-and-cell-sheet-technology-for-the-development-of-a-multiscale-tissue-engineered-ligament-construct-telc
#7
Cedryck Vaquette, P T Sudheesh Kumar, Eugen Bogdan Petcu, Saso Ivanovski
Ligament tissue rupture is a common sport injury. Although current treatment modalities can achieve appropriate reconstruction of the damaged ligament, they present significant drawbacks, mostly related to reduced tissue availability and pain associated with tissue harvesting. Stem cell based tissue regeneration combined with electrospun scaffolds represents a novel treatment method for torn ligaments. In this study, a low fiber density polycaprolactone (PCL) electrospun mesh and sheep mesenchymal stem cells (sMSCs) were used to develop tissue engineered ligament construct (TELC) in vitro...
February 7, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28169513/multilayer-nanoscale-encapsulation-of-biofunctional-peptides-to-enhance-bone-tissue-regeneration-in-vivo
#8
Piergiorgio Gentile, Ana Marina Ferreira, Jill T Callaghan, Cheryl A Miller, Joss Atkinson, Christine Freeman, Paul V Hatton
Bone tissue healing is a dynamic process that is initiated by the recruitment of osteoprogenitor cells followed by their migration, proliferation, differentiation, and development of a mineralizing extracellular matrix. The work aims to manufacture a functionalized porous membrane that stimulates early events in bone healing for initiating a regenerative cascade. Layer-by-layer (LbL) assembly is proposed to modify the surface of osteoconductive electrospun meshes, based on poly(lactic-co-glycolic acid) and nanohydroxyapatite, by using poly(allylamine hydrochloride) and poly(sodium 4-styrenesulfonate) as polyelectrolytes...
February 7, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28154746/bone-ingrowth-to-ti-fibre-knit-block-with-high-deformability
#9
Yoko Henmi, Yoshihito Naito, Ryo Jimbo, Yohei Jinno, Kazumitsu Sekine, Kenichi Hamada
OBJECTIVES: The objective of this study is to develop a Ti fibre knit block without sintering, and to evaluate its deformability and new bone formation in vivo. MATERIAL AND METHODS: A Ti fibre with a diameter of 150 μm was knitted to fabricate a Ti mesh tube. The mesh tube was compressed in a metal mould to fabricate porous Ti fibre knit blocks with three different porosities of 88%, 69%, and 50%. The elastic modulus and deformability were evaluated using a compression test...
October 2016: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/28139110/-abdominal-traumatic-evisceration-reconstruction-abdominal-wall-with-biologic-mesh-and-negative-pressure-therapy
#10
M Jiménez Gómez, N Betancor Rivera, J Lima Sánchez, J R Hernández Hernández
INTRODUCTION: Abdominal traumatic evisceration as a result of high energy trauma is uncommon. Once repaired the possible internal damage, an abdominal wall defect of high complexity may exist, whose reconstruction represents a surgical challenge. CASE REPORT: Politraumatized male with important abdominal muculocutaneous avulsion and evisceration. After initial repair, the patient developed a big eventration in which we use a porcine dermis-derived mesh (Permacol(TM)), a safe and effective alternative in abdominal wall repair, thanks to its seamless integration with other tissues, even when exposed...
April 10, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/28134701/the-role-of-the-surgeon-on-outcomes-of-vaginal-prolapse-surgery-with-mesh
#11
Karyn S Eilber, Marianna Alperin, Aqsa Khan, Ning Wu, Chris L Pashos, J Quentin Clemens, Jennifer T Anger
INTRODUCTION: Adverse outcomes after surgery for pelvic organ prolapse (POP) with mesh are often attributed to the mesh material with little attention paid to the influence of surgeon factors. We used a national data set to determine whether surgeon case volume and specialty influenced vaginal prolapse surgery outcomes with mesh. MATERIALS AND METHODS: Public Use File data on a 5% random national sample of female Medicare beneficiaries were obtained from the Centers for Medicare and Medicaid Services...
January 27, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28132034/-clinical-evaluation-of-the-new-antiseptic-meshes
#12
M Gogoladze, M Kiladze, T Chkhikvadze, D Jiqia
Improving the results of hernia treatment and prevention of complications became a goal of our research which included two parts - experimental and clinical. Histomorphological and bacteriological researches showed that the best result out of the 3 control groups was received in case of covering implant "Coladerm"+ with chlorhexidine. Based on the experiment results working process continued in clinics in order to test and introduce new "coladerm"+ chlorhexidine covered poliprophilene meshes into practice. For clinical illustration there were 60 patients introduced to the research who had hernioplasty procedures by different nets: I group - standard meshes+"coladerm"+chlorhexidine, 35 patients; II group - standard meshes +"coladerm", 15 patients; III group - standard meshes, 10 patients...
December 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28130823/effects-of-aging-upon-the-host-response-to-implants
#13
Daniel Hachim, Na Wang, Samuel T Lopresti, Elizabeth C Stahl, Yuta U Umeda, Rahul D Rege, Sean T Carey, Deepa Mani, Bryan N Brown
Macrophage polarization during the host response is now a well-accepted predictor of outcomes following material implantation. Immunosenescence, dysregulation of macrophage function, and delayed resolution of immune responses in aged individuals have all been demonstrated, suggesting that host responses to materials in aged individuals should differ from those in younger individuals. However, few studies examining the effects of aging upon the host response have been performed. The present work sought to elucidate the impacts of aging upon the host response to polypropylene mesh implanted into 8-week and 18-month-old mice...
January 28, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28124074/mri-visible-fe3o4-polypropylene-mesh-3d-reconstruction-of-spatial-relation-to-bony-pelvis-and-neurovascular-structures
#14
Luyun Chen, Florian Lenz, Céline D Alt, Christof Sohn, John O De Lancey, Kerstin A Brocker
INTRODUCTION AND HYPOTHESIS: To demonstrate mesh magnetic resonance imaging (MRI) visibility in living women, the feasibility of reconstructing the full mesh course in 3D, and to document its spatial relationship to pelvic anatomical structures. METHODS: This is a proof of concept study of three patients from a prospective multi-center trial evaluating women with anterior vaginal mesh repair using a MRI-visible Fe3O4 polypropylene implant for pelvic floor reconstruction...
January 25, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28121970/resorbable-mesh-cranioplasty-repair-of-bilateral-cerebrospinal-fluid-leaks-following-pediatric-simultaneous-bilateral-auditory-brainstem-implant-surgery
#15
Giacomo Colletti, Marco Mandalà, Vittorio Colletti, Alberto Deganello, Fabiana Allevi, Liliana Colletti
OBJECTIVE: To present a child with cochlear nerve deficiency (CND) who received simultaneous bilateral simultaneous auditory brainstem implants (BS-ABI) and subsequently presented with bilateral cerebrospinal fluid (CSF) leaks unresponsive to standard treatments. To propose a novel rigid retrosigmoid cranioplasty for treating and preventing CSF leaks in children at high risk for this complication. PATIENT: A 3.5-year-old child with CND, vertebral defects, anal atresia, cardiac defects, tracheo-esophageal fistula, renal anomalies, and limb abnormalities, coloboma, heart defect, atresia choanae, retarded growth and development, genital abnormality, and ear abnormality, Arnold Chiari malformation, previous treated tracheo-esophageal fistula underwent BS-ABI...
January 24, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28120579/sacral-reconstruction-with-a-3d-printed-implant-after-hemisacrectomy-in-a-patient-with-sacral-osteosarcoma-1-year-follow-up-result
#16
Doyoung Kim, Jun Young Lim, Kyu Won Shim, Jung Woo Han, Seong Yi, Do Heum Yoon, Keung Nyun Kim, Yoon Ha, Gyu Yeul Ji, Dong Ah Shin
Pelvic reconstruction after sacral resection is challenging in terms of anatomical complexity, excessive loadbearing, and wide defects. Nevertheless, the technological development of 3D-printed implants enables us to overcome these difficulties. Here, we present a case of sacral osteosarcoma surgically treated with hemisacrectomy and sacral reconstruction using a 3D-printed implant. The implant was printed as a customized titanium prosthesis from a 3D real-sized reconstruction of a patient's CT images. It consisted mostly of a porous mesh and incorporated a dense strut...
March 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28120065/skull-bone-defects-reconstruction-with-custom-made-titanium-graft-shaped-with-electron-beam-melting-technology-preliminary-experience-in-a-series-of-ten-patients
#17
Natale Francaviglia, Rosario Maugeri, Antonino Odierna Contino, Francesco Meli, Vito Fiorenza, Gabriele Costantino, Roberto Giuseppe Giammalva, Domenico Gerardo Iacopino
BACKGROUND: Cranioplasty represents a challenge in neurosurgery. Its goal is not only plastic reconstruction of the skull but also to restore and preserve cranial function, to improve cerebral hemodynamics, and to provide mechanical protection of the neural structures. The ideal material for the reconstructive procedures and the surgical timing are still controversial. Many alloplastic materials are available for performing cranioplasty and among these, titanium still represents a widely proven and accepted choice...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28116550/implantation-of-a-poly-l-lactide-gcsf-functionalized-scaffold-in-a-model-of-chronic-myocardial-infarction
#18
Cristiano Spadaccio, Francesco Nappi, Federico De Marco, Pietro Sedati, Chiara Taffon, Antonio Nenna, Anna Crescenzi, Massimo Chello, Marcella Trombetta, Ivancarmine Gambardella, Alberto Rainer
A previously developed poly-L-lactide scaffold releasing granulocyte colony-stimulating factor (PLLA/GCSF) was tested in a rabbit chronic model of myocardial infarction (MI) as a ventricular patch. Control groups were constituted by healthy, chronic MI and nonfunctionalized PLLA scaffold. PLLA-based electrospun scaffold efficiently integrated into a chronic infarcted myocardium. Functionalization of the biopolymer with GCSF led to increased fibroblast-like vimentin-positive cellular colonization and reduced inflammatory cell infiltration within the micrometric fiber mesh in comparison to nonfunctionalized scaffold; PLLA/GCSF polymer induced an angiogenetic process with a statistically significant increase in the number of neovessels compared to the nonfunctionalized scaffold; PLLA/GCSF implanted at the infarcted zone induced a reorganization of the ECM architecture leading to connective tissue deposition and scar remodeling...
January 23, 2017: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/28115812/ivus-guided-implantation-of-bioresorbable-vascular-scaffolds-for-very-late-paclitaxel-stent-thrombosis
#19
Zhe-Zhong Lin, Wei-Ting Chang, Chun-Yen Chiang, Zhih-Cherng Chen, Po-Ming Ku
Bioresorbable vascular scaffold (BVS) implantation has been shown to be safe in patients with stable coronary disease, and effective against the thrombotic lesion and the in-stent restenosis (ISR) of the drug-eluting stent (DES). BVSs have the advantages of a snow racket concept, positive vessel remodeling, and better conformability compared with DES in acute coronary syndrome (ACS). We report on a young patient with ST-elevation myocardial infarction (STEMI) who presented to our emergency department arising from very late stent thrombosis (VLST) of a 2...
January 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/28108780/cement-augmented-screws-in-a-cervical-two-level-corpectomy-with-anterior-titanium-mesh-cage-reconstruction-a-biomechanical-study
#20
Sebastian Hartmann, Claudius Thomé, Anja Tschugg, Johannes Paesold, Pujan Kavakebi, Werner Schmölz
STUDY DESIGN: Biomechanical investigation. PURPOSE: Cervical two-level corpectomies with anterior-only instrumentation are associated with a high rate of implant-related complications. These procedures, therefore, often require an additional dorsal instrumentation to prevent screw loosening. Cement augmentation of the anterior screws in two-level corpectomies might stabilize the construct, so that a second dorsal procedure could be avoided. To evaluate the screw anchorage in cervical anterior-only procedures, an ex vivo evaluation of the range of motion (ROM) in two-level corpectomies (C4 and C5), with and without cement augmentation of the anterior screws, was carried out in this study...
January 21, 2017: European Spine Journal
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