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'Neural mobilisation'

Cato A Basson, Aimee Stewart, Witness Mudzi
BACKGROUND: Neck pain is a common musculoskeletal complaint and is often associated with shoulder or arm pain. There is a paucity of information on effective treatment for neck and arm pain, such as radiculopathy or cervico-brachial pain. Guidelines recommend neck mobilisation/ manipulation, exercises and advice as the treatment for neck pain, and neck and arm pain. There are a few studies that have used neural mobilisation as the treatment for cervico-brachial pain. Although results seem promising the studies have small sample sizes that make it difficult to draw definite conclusions...
2014: BMC Musculoskeletal Disorders
Priyan R Landham, Holly L A Baker-Rand, Samuel J Gilbert, Phillip Pollintine, Deborah J Annesley-Williams, Michael A Adams, Patricia Dolan
BACKGROUND CONTEXT: The vertebral augmentation procedures, vertebroplasty and kyphoplasty, can relieve pain and facilitate mobilization of patients with osteoporotic vertebral fractures. Kyphoplasty also aims to restore vertebral body height before cement injection and so may be advantageous for more severe fractures. PURPOSE: The purpose of this study was to compare the ability of vertebroplasty and kyphoplasty to restore vertebral height, shape, and mechanical function after severe vertebral wedge fractures...
April 1, 2015: Spine Journal: Official Journal of the North American Spine Society
Daisuke Sakai, Sibylle Grad
The healthy intervertebral disc (IVD) fulfils the essential function of load absorption, while maintaining multi-axial flexibility of the spine. The interrelated tissues of the IVD, the annulus fibrosus, the nucleus pulposus, and the cartilaginous endplate, are characterised by their specific niche, implying avascularity, hypoxia, acidic environment, low nutrition, and low cellularity. Anabolic and catabolic factors balance a slow physiological turnover of extracellular matrix synthesis and breakdown. Deviations in mechanical load, nutrient supply, cellular activity, matrix composition and metabolism may initiate a cascade ultimately leading to tissue dehydration, fibrosis, nerve and vessel ingrowth, disc height loss and disc herniation...
April 2015: Advanced Drug Delivery Reviews
Jorge Oliver-De La Cruz, Josefa Carrión-Navarro, Noemí García-Romero, Antonio Gutiérrez-Martín, Elisa Lázaro-Ibáñez, Carmen Escobedo-Lucea, Rosario Perona, Cristobal Belda-Iniesta, Angel Ayuso-Sacido
OBJECTIVES: A number of neurodegenerative diseases progress with a loss of myelin, which makes them candidate diseases for the development of cell-replacement therapies based on mobilisation or isolation of the endogenous neural/glial progenitor cells, in vitro expansion, and further implantation. Cells expressing A2B5 or PDGFRA/CNP have been isolated within the pool of glial progenitor cells in the subcortical white matter of the normal adult human brain, all of which demonstrate glial progenitor features...
2014: PloS One
Peter Andras, Alina Andras
Type 2 diabetes is a serious disease that is affecting an increasing part of the population in most countries. A new hypothesis is presented in this paper about the underlying causes and mechanisms that lead to the development of this disease. It is proposed that the disease is the price that the organism pays for having improved cognitive performance that is achieved through increased level of neurite growth dynamics of neurons. The suggested mechanism of the disease development involves neural centres that deal with the sensing of fat and sugar levels in the blood and cerebro-spinal fluid, the regulation of the mobilisation of these resources in the body, the regulation of the storage of sugar and fat in the body, and the regulation of feeding behaviour...
February 2013: Medical Hypotheses
Nicholas Benikos, Stuart J Johnstone, Steven J Roodenrys
Neural activity underlying executive functions is subject to modulation as a result of increasing cognitive demands and practice. In the present study, we examined these modulatory effects by varying task difficulty, as manipulated by reaction time deadline (RTD), on inhibitory control during a single Go/Nogo training session (8 blocks; 70% Go). Sixty adults were randomly assigned to one of three task difficulty conditions: High (n=20), Medium (n=20) and Low (n=20), with RTDs of 300, 500 or 1000 ms, respectively...
March 2013: International Journal of Psychophysiology
S Stötzel, F Krause, H Bergert
OBJECTIVE: Surgery of carotid artery stenosis is an evidence-based procedure. In Germany approximately 25 percent of the strokes are caused by arteriosclerotic processes in the extracranial internal carotid artery and are consequently potentially avoidable by an appropriate treatment. The symptoms, the stenosis degree as well as the perioperative risk represent the basis for the indication. The perioperative complication rate should be under 3 percent for those cases with asymptomatic stenoses and under 6 percent for those with symptomatic stenoses...
October 2012: Zentralblatt Für Chirurgie
Perihan Ekmekci, Zuleyha Kazak Bengisun, Burak Akan, Baturay Kansu Kazbek, Kemal Sefa Ozkan, Arif Hikmet Suer
PURPOSE: The aim of this prospective randomised double-blind study is to investigate the effect of magnesium added to local anaesthetics on postoperative VAS scores, total opioid consumption, time to first mobilisation, patient satisfaction and rescue analgesic requirements in arthroscopic ACL reconstruction surgery. METHODS: A total of 107 American Society of Anaesthesiologists physical status grade I and II patients between 18 and 65 years of age who were scheduled to undergo elective anterior crucial ligament (ACL) reconstruction with hamstring autografts were enrolled in the study...
May 2013: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Mandy Rossignol, Pierre Philippot, Cécile Bissot, Simon Rigoulot, Salvatore Campanella
Behavioural studies have used spatial cueing designs extensively to investigate emotional biases in individuals exhibiting clinical and sub-clinical anxiety. However, the neural processes underlying the generation of these biases remain largely unknown. In this study, people who scored unusually high or low on scales of social anxiety performed a spatial cueing task. They were asked to discriminate the orientation of arrows appearing at the location previously occupied by a lateralised cue (consisting of a face displaying an emotional or a neutral expression) or at the empty location...
June 15, 2012: Brain Research
E Santos Leal
No abstract text is available yet for this article.
January 27, 2012: Scoliosis
Ganeshwaran Shivapathasundram, Marcus A Stoodley
Diastematomyelia is a congenital condition where the spinal cord is split by a bony or cartilaginous septum. Neurological signs and symptoms arise when this septum tethers the spinal cord. Surgical detethering often improves symptoms; however, recurrent tethering of the cord is increasingly recognised as a long-term complication. In order to prevent retethering many techniques have been used, including early patient mobilisation and sectioning of the cord. Dorsal expansile duroplasty, using synthetic grafts, is a commonly used technique to prevent recurrent dorsal tethering...
April 2012: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Geoffrey J Faulkner
Mobile genetic elements feature prominently in mammalian genome evolution. Several transposition-competent retrotransposon families (L1, Alu, SVA) remain active in the human germ line, leading to pathogenesis as well as genome structural variation across the global population. High-throughput screening approaches have recently been developed to detect retrotransposon insertion polymorphisms. Evidence produced by these and other genome-scale technologies indicates an expanded role for retrotransposition in human biology, including somatic mobilisation in the developing embryo and in neural cells...
June 6, 2011: FEBS Letters
Robert Ritchie, Mark Sullivan
Erectile dysfunction (ED) is common and a significant contributor to poor quality of life and psychosocial morbidity in men. Normal erectile function requires effective co-ordination between a number of complex neural pathways. Penile tumescence occurs in response to rapid arterial inflow to the corpora cavernosa with simultaneous venous outflow restriction due to expansion of the lacunar spaces. This process is under both central and local neuromediation. Endothelins are potent vasoconstrictor peptides that cause strong, slowly developing but sustained contraction of trabecular smooth muscles cells of the corpora cavernosa...
June 2011: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Axel Schäfer, Toby Hall, Gerd Müller, Kathryn Briffa
The objective is to determine if pain and disability outcomes of patients treated with neural mobilisation differ for sub-classifications of low back and leg pain (LB&LP). Radiating leg pain is a poor prognostic factor for recovery in patients with LBP. To improve outcome, a new pathomechanism-based classification system was proposed: neuropathic sensitization (NS), denervation (D), peripheral nerve sensitization (PNS) and musculoskeletal (M). Seventy-seven patients with unilateral LB&LP were recruited. Following classification, all subjects were treated seven times with neural mobilisation techniques...
March 2011: European Spine Journal
A Seuser, T Wallny, A Kurth, P Berdel
Rehabilitation and physical therapy in the sense of functional health is based on the international classification of function. It takes in two considerations: function and structure of the body and their influence on personal and social activity. The integrative concept of joint function translates the basic concept of body function and structure on to the motion of the locomotive system. Stability needs motoric control. Motoric control and the integrated neural components are to be influenced through regulation of muscle tonus (massage, manual therapy, medical training therapy, electrotherapy and thermotherapy)...
November 2010: Hämostaseologie
Anita Gross, Jordan Miller, Jonathan D'Sylva, Stephen J Burnie, Charles H Goldsmith, Nadine Graham, Ted Haines, Gert Brønfort, Jan L Hoving
BACKGROUND: Manipulation and mobilisation are often used, either alone or combined with other treatment approaches, to treat neck pain. OBJECTIVES: To assess if manipulation or mobilisation improves pain, function/disability, patient satisfaction, quality of life, and global perceived effect in adults with acute/subacute/chronic neck pain with or without cervicogenic headache or radicular findings. SEARCH STRATEGY: CENTRAL (The Cochrane Library 2009, issue 3) and MEDLINE, EMBASE, Manual Alternative and Natural Therapy, CINAHL, and Index to Chiropractic Literature were updated to July 2009...
2010: Cochrane Database of Systematic Reviews
Max Aebi
The goals of any treatment of cervical spine injuries are: return to maximum functional ability, minimum of residual pain, decrease of any neurological deficit, minimum of residual deformity and prevention of further disability. The advantages of surgical treatment are the ability to reach optimal reduction, immediate stability, direct decompression of the cord and the exiting roots, the need for only minimum external fixation, the possibility for early mobilisation and clearly decreased nursing problems. There are some reasons why those goals can be reached better by anterior surgery...
March 2010: European Spine Journal
J H Coert, M W Stenekes, A M J Paans, J-P A Nicolai, B M De Jong
After flexor tendon injury, most attention is given to the quality of the tendon repair and postoperative early passive dynamic mobilisation. Schemes for active mobilisation have been developed to prevent tendon adhesions and joint stiffness. This paper describes five patients to demonstrate the cerebral consequences of immobilisation allowing only passive movements, which implies a prolonged absence of actual motor commands. At the end of such immobilisation, PET imaging revealed reduced blood flow in specific motor areas, associated with temporary loss of efficient motor control...
August 2009: Journal of Hand Surgery, European Volume
Richard F Ellis, Wayne A Hing
Neural mobilization is a treatment modality used in relation to pathologies of the nervous system. It has been suggested that neural mobilization is an effective treatment modality, although support of this suggestion is primarily anecdotal. The purpose of this paper was to provide a systematic review of the literature pertaining to the therapeutic efficacy of neural mobilization. A search to identify randomized controlled trials investigating neural mobilization was conducted using the key words neural mobilisation/mobilization, nerve mobilisation/mobilization, neural manipulative physical therapy, physical therapy, neural/nerve glide, nerve glide exercises, nerve/neural treatment, nerve/neural stretching, neurodynamics, and nerve/neural physiotherapy...
2008: Journal of Manual & Manipulative Therapy
O E Anastasiou, M P Yavropoulou, I Kesisoglou, K Kotsa, J G Yovos
Intracerebroventricular (icv) injection of neuropeptide Y (NPY), which is a widely-distributed neurotransmitter, into the paraventricular nuclear area has been shown previously to increase secretion of insulin and glucagon from the pancreatic islets. Vasoactive intestinal polypeptide (VIP) is a 28-amino-acid peptide that is associated with the mobilisation of energy during situations of energy depletion, such as fasting and exercise. VIP has also been reported to alter insulin and glucagon levels in a glucose-dependent manner...
February 2009: Neuropeptides
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