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https://www.readbyqxmd.com/read/27898935/estimation-of-genetic-parameters-for-traits-associated-with-reproduction-lactation-and-efficiency-in-sows
#1
D M Thekkoot, R A Kemp, M F Rothschild, G S Plastow, J C M Dekkers
Increased milk production due to high litter size, coupled with low feed intake, results in excessive mobilization of sow body reserves during lactation, which can have detrimental effects on future reproductive performance. A possibility to prevent this is to improve sow lactation performance genetically, along with other traits of interest. The aim of this study was to estimate breed-specific genetic parameters (by parity, between parities, and across parities) for traits associated with lactation and reproduction in Yorkshire and Landrace sows...
November 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27888086/effects-of-smoking-on-subjective-and-objective-measures-of-pain-intensity-functional-impairment-and-health-related-quality-of-life-in-lumbar-degenerative-disc-disease
#2
Holger Joswig, Martin N Stienen, Nicolas R Smoll, Marco V Corniola, Ivan Chau, Karl Schaller, Gerhard Hildebrandt, Oliver P Gautschi
BACKGROUND: Numerous studies assessed the effects of smoking on lumbar degenerative disc disease (DDD); they focused on patient-reported outcomes measures (PROMs) and yielded conflicting results. METHODS: In this two-center study on consecutive patients receiving surgical treatment for lumbar DDD, subjective functional impairment (SFI) in terms of PROMs including visual analog scale back and leg pain, Roland-Morris, Oswestry Disability Index, Euro-Qol, Short Form-12 physical component summary was determined at baseline, three days, six weeks, six months and one year postoperatively...
November 22, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27876000/comparison-of-repair-of-peripheral-nerve-transection-in-predegenerated-muscle-with-and-without-a-vein-graft
#3
Jamshid Mohammadi, Hamdollah Delaviz, Bahram Mohammadi, Hamoun Delaviz, Parastou Rad
BACKGROUND: Despite substantial research into the topic and valiant surgical efforts, reconstruction of peripheral nerve injury remains a challenging surgery. This study was conducted to evaluate the effectiveness of axonal regeneration of a transected sciatic nerve through a vein conduit containing degenerated skeletal muscle compared with axonal regeneration in a transected sciatic nerve through degenerated skeletal muscle alone. METHODS: In two of the three experimental rat groups, 10 mm of the left sciatic nerve was transected and removed...
November 22, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27862486/characterisation-of-maternal-human-leukocyte-antigen-class-i-antibodies-in-suspected-foetal-and-neonatal-alloimmune-thrombocytopenia
#4
E Refsum, A Mörtberg, J Dahl, S Meinke, M-K Auvinen, M Westgren, M Reilly, P Höglund, A Wikman
OBJECTIVES: To investigate the specificities and level of HLA class I antibodies in selected cases referred for suspected foetal and neonatal alloimmune thrombocytopenia (FNAIT). BACKGROUND: FNAIT occurs in 1 : 1-2000 live births, whereas maternal immunisation against human leukocyte antigen (HLA) class I is common. Whether HLA class I antibodies alone can cause FNAIT is debatable. MATERIAL AND METHODS: A total of 260 patient samples were referred between 2007 and 2012...
November 9, 2016: Transfusion Medicine
https://www.readbyqxmd.com/read/27834859/a-precision-microbiome-approach-using-sucrose-for-selective-augmentation-of-staphylococcus-epidermidis-fermentation-against-propionibacterium-acnes
#5
Yanhan Wang, Ming-Shan Kao, Jinghua Yu, Stephen Huang, Shinta Marito, Richard L Gallo, Chun-Ming Huang
Acne dysbiosis happens when there is a microbial imbalance of the over-growth of Propionibacterium acnes (P. acnes) in the acne microbiome. In our previous study, we demonstrated that Staphylococcus epidermidis (S. epidermidis, a probiotic skin bacterium) can exploit glycerol fermentation to produce short-chain fatty acids (SCFAs) which have antimicrobial activities to suppress the growth of P. acnes. Unlike glycerol, sucrose is chosen here as a selective fermentation initiator (SFI) that can specifically intensify the fermentation activity of S...
November 9, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27818926/pharmacokinetic-evaluation-of-shenfu-injection-in-beagle-dogs-after-intravenous-drip-administration
#6
Yuqiao Zhang, Dali Tian, Yuyou Huang, Ling Li, Juan Mao, Juan Tian, Jinsong Ding
Shenfu Injection (SFI) is a well-defined Chinese herbal formulation that is obtained from red ginseng and processed aconite root. The main active constituents in SFI are ginsenosides and aconitum alkaloids. In this work, ginsenosides (ginsenoside Rg1, ginsenoside Rb1 and ginsenoside Rc) and aconitum alkaloids (benzoylmesaconine and fuziline) were used as the index components to explore the pharmacokinetic behavior of SFI. A selective and sensitive HPLC-MS/MS method was developed for the quantification of ginsenosides and aconitum alkaloids in dog plasma and was used to characterize the pharmacokinetics of the five index components after intravenous drip of three different dosages of SFI in beagle dogs...
November 2016: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/27807516/the-morphological-and-functional-effects-of-exercise-in-the-aquatic-environment-performed-before-and-or-after-sciatic-nerve-compression-in-wistar-rats
#7
Camila Mayumi Martin Kakihata, Jéssica Aline Malanotte, Jhenifer Karvat, Rose Meire Costa Brancalhão, Lucinéia de Fátima Chasko Ribeiro, Gladson Ricardo Flor Bertolini
The aim of this study was to evaluate the effects of exercise in the aquatic environment, performed before and/or after sciatic nerve compression in Wistar rats on morphological and functional parameters. Twenty-five Wistar rats were divided into the following groups: control (C), lesion (L), trained+lesion (TL), lesion+exercise (LE), and training+lesion+exercise (TLE), who underwent right sciatic nerve compression on day 21 of the experiment. The TL and TLE groups were submitted to a jumping exercise in a water environment for 20 days prior to injury and the LE and TLE groups after injury...
October 2016: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/27780372/sweep-frequency-impedance-measures-in-young-infants-developmental-characteristics-from-birth-to-6-months
#8
Venkatesh Aithal, Joseph Kei, Carlie Driscoll, Michio Murakoshi, Hiroshi Wada
OBJECTIVE: International Journal of Audiology To study the developmental characteristics of sweep frequency impedance (SFI) measures in healthy infants from birth to 6 months. DESIGN: All infants were assessed using high-frequency tympanometry (HFT), distortion product otoacoustic emission (DPOAE) and SFI tests. SFI measures consisted of measurement of resonance frequency (RF) and mobility (ΔSPL) of the outer and middle ear. A mixed model analysis of variance was applied to the SFI data to examine the effect of age on RF and ΔSPL...
October 26, 2016: International Journal of Audiology
https://www.readbyqxmd.com/read/27771457/identification-of-nf-%C3%AE%C2%BAb-inhibitors-following-shenfu-injection-and-bioactivity-integrated-uplc-q-tof-ms-and-screening-for-related-anti-inflammatory-targets-in-vitro-and-in-silico
#9
Pan Li, Bin Lv, Xiaoqing Jiang, Ting Wang, Xianghui Ma, Nianwei Chang, Xiaoying Wang, Xiumei Gao
ETHNOPHARMACOLOGICAL RELEVANCE: Shenfu injection (SFI) is a commercial medicinal product approved by the China Food and Drug Administration that is widely used in the treatment of stroke and coronary heart disease. However, the material basis and the mechanism of SFI are not fully understood. AIM OF THE STUDY: With network pharmacology analysis, our research committed to identify the anti-inflammatory ingredients and mechanism of SFI by combining high-throughput screening...
October 19, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27703860/influence-of-age-and-sex-on-winter-site-fidelity-of-sanderlings-calidris-alba
#10
Pedro M Lourenço, José A Alves, Jeroen Reneerkens, Ah Jelle Loonstra, Peter M Potts, José P Granadeiro, Teresa Catry
Many migratory bird species show high levels of site fidelity to their wintering sites, which confers advantages due to prior knowledge, but may also limit the ability of the individual to move away from degrading sites or to detect alternative foraging opportunities. Winter site fidelity often varies among age groups, but sexual differences have seldom been recorded in birds. We studied a population of individually colour-marked sanderlings wintering in and around the Tejo estuary, a large estuarine wetland on the western coast of Portugal...
2016: PeerJ
https://www.readbyqxmd.com/read/27698635/distal-inside-out-epineural-sliding-technique-to-repair-segmental-nerve-defects
#11
Toni Luokkala, Jorma Ryhänen, Juha Näpänkangas, Teemu V Karjalainen
Background: The repair of a segmental peripheral nerve injury is a clinical challenge. Several studies have been performed to determine superior methods for overcoming nerve gaps. The purpose of this study was to investigate if the inside-out slided epineurium of the distal segment of an injured nerve can serve as a conduit to bridge a short nerve defect (10 mm). Methods: Nineteen sciatic nerves in Sprague-Dawley rats were transected, and a 10-mm gap was left between the ends. A section of distal epineurium was pulled inside out to bridge the gap...
September 2016: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/27641994/olfactory-ensheathing-glia-cell-therapy-and-tubular-conduit-enhance-nerve-regeneration-after-mouse-sciatic-nerve-transection
#12
Camila Oliveira Goulart, Daniella de Freitas Pereira Ângelo Durço, Lítia Alves de Carvalho, Júlia Teixeira Oliveira, Lucinéia Alves, Leny A Cavalcante, Ana Maria Blanco Martinez
The regenerative potential of the peripheral nervous system (PNS) is widely known, but functional recovery, particularly in humans, is seldom complete. Therefore, it is necessary to resort to strategies that induce or potentiate the PNS regeneration. Our main objective was to test the effectiveness of Olfactory Ensheathing Cells (OEC) transplantation into a biodegradable conduit as a therapeutic strategy to improve the repair outcome after nerve injury. Sciatic nerve transection was performed in C57BL/6 mice; proximal and distal stumps of the nerve were sutured into the collagen conduit...
November 1, 2016: Brain Research
https://www.readbyqxmd.com/read/27631175/study-of-transected-sciatic-nerve-repair-by-amniotic-membrane-with-betamethasone-in-adult-albino-wistar-rats
#13
Seyed Homayoon Sadraie, Kazem Parivar, Farzaneh Arabi, Mehrnaz Moattari, Gholamreza Kaka, Korosh Mansouri
BACKGROUND: The aim of this study was to determine the effects of amniotic membrane impregnated with betamethasone on regeneration of transected sciatic nerve injury in adult albino Wister rats. METHODS: In this research, 42 male adult rats were divided into six equal groups. 1) Normal (intact) group: healthy rats without any injury; 2) CONTROL GROUP: sciatic nerve was cut and sutured; 3) Sham group: 0.2 mL culture medium was injected on the epineurium in the injury; 4) Amniotic membrane group (AM): Acellular amniotic membrane was used around the damaged sciatic nerve; 5) Betamethasone group (B): 0...
September 2016: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/27627712/direct-tubular-lumbar-microdiscectomy-for-far-lateral-disc-herniation-a-modified-approach
#14
Timothy L T Siu, Kainu Lin
OBJECTIVE: The concept of minimally invasive tubular discectomy is based on precise placement of the retractor over the surgical target to minimize collateral tissue trauma. For far lateral disc herniation, the junction between the pars and the transverse process has generally been adopted as the target for facilitating early nerve root exposure; however, this may limit access to the disc space and increase the risks of iatrogenic neuralgia. An alternative approach to help address these issues involving docking the retractor caudally directly over the disc space with the aid of a microscope is here proposed...
August 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/27614966/effects-of-shenfu-injection-on-cerebral-metabolism-in-a-porcine-model-of-cardiac-arrest
#15
Qin Yin, Cai-Jun Wu, Jun Yang, Chen-Chen Hang, Chun-Sheng Li
OBJECTIVE: To investigate the effects of Shenfu Injection (, SFI) on cerebral metabolism in a porcine model of cardiac arrest (CA). METHODS: Thirty Wuzhishan minipigs were randomly assigned to the control group (n=6), epinephrine group (EP group, n=12) and Sfigroup (n=12). After 8 min of untreated ventricular fifibrillation (VF), pigs in the EP group or Sfigroup were administered with either EP (0.02 mg/kg) or Sfi(1.0 mL/kg), respectively. After successful resuscitation, cerebrospinal fluid (CSF) levels of glucose, pyruvate, lactate, glutamate and glycerol were measured at 1, 6, 12 and 24 h after recover from spontaneous circulation (ROSC)...
September 10, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27614451/effects-of-shen-fu-injection-on-apoptosis-of-regulatory-t-lymphocytes-in-spleen-during-post-resuscitation-immune-dysfunction-in-a-porcine-model-of-cardiac-arrest
#16
Wei Gu, Qian Zhang, Chun-Sheng Li
OBJECTIVE: To investigate whether Shen-Fu Injection (, SFI) reduces post-resuscitation immune dysfunction in a porcine model of cardiac arrest by modulating apoptosis of regulatory T lymphocytes (Treg) in the spleen. METHODS: After 8-min untreated ventricular fibrillation and 2-min basic life support, 24 pigs were divided into 3 groups with a random number table, i.e. SFI group, epinephrine (EP) group, and saline (SA) group (8 in each group), which received central venous injection of SFI (1...
September 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27612932/program-use-and-outcome-change-in-a-web-based-trauma-intervention-individual-and-social-factors
#17
Zhiyun Wang, Jianping Wang, Andreas Maercker
BACKGROUND: Insight into user adherence to Web-based intervention programs and into its relationship to intervention effect is needed. OBJECTIVE: The objective of this study was to examine use of a Web-based self-help intervention program, the Chinese version of My Trauma Recovery (CMTR), among Chinese traumatized individuals, and to investigate the relationship between program use and user characteristics before the intervention and change in outcomes after the intervention and at 3-months' follow-up...
September 9, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27600550/-percezione-e-soddisfazione-degli-studenti-in-ostetricia-al-primo-anno-di-tirocinio-clinico-studio-osservazionale-multicentrico
#18
Dania Comparcini, Marco Tomietto, Valentina Simonetti, Francesca Zambri, Giancarlo Cicolini
AIM: To explore the first year midwifery students' clinical learning experience and satisfaction; to analyse the association between students' satisfaction and individual motivation. METHOD: The multicentre cross-sectional study was carried out in four Italian midwifery degree courses. A convenience sample of 61 students filled out the Italian version of the "Clinical Learning Environment and Supervision plus Nurse Teacher (CLES+T) scale" after the conclusion of their first clinical placement...
April 2016: Professioni Infermieristiche
https://www.readbyqxmd.com/read/27593810/the-effect-of-memantine-on-functional-recovery-of-the-sciatic-nerve-crush-injury-in-rat
#19
Mohammad-Bagher Ghayour, Arash Abdolmaleki, Morteza Behnam-Rassouli
AIM: Following severe peripheral nerve injury (PNI), regeneration is often insufficient and functional recovery is incomplete. In this regard, glutamate NMDA receptor antagonist such as Memantine have been shown to have neuroprotective effects. We evaluated the effects of Memantine against sciatic nerve crush injury in male Wistar Rats. MATERIAL AND METHODS: Memantine or vehicle was given parenteraly to rats for 7 days postoperative. In Memantine treatment groups, a single dose of agent (5 and 10 mg/kg) was administered daily...
February 5, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27593797/the-effect-of-cerebro-spinal-fluid-in-collagen-guide-channel-on-sciatic-nerve-regeneration-in-rat
#20
Gholam Hossein Farjah, Mohammad Amin Dolatkhah, Bagher Pourheidar, Behnam Heshmatian
AIM: The aim of this study was to evaluate the effect of cerebro-spinal fluid (CSF) in nerve regeneration across the collagen guide channel in comparison with autograft. MATERIAL AND METHODS: Forty adult male rats (250-300g) were randomized into (1) collagen channel + CSF, (2) collagen channel + normal saline (NS), (3) autograft, and (4) sham surgery groups. The left sciatic nerve was exposed and a 10mm nerve segment was cut and removed. In the collagen groups, the proximal and distal cuts ends of sciatic nerve were telescoped into the nerve guides and CSF or NS injected into collagen conduit...
December 28, 2015: Turkish Neurosurgery
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