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https://www.readbyqxmd.com/read/28324299/fatal-familial-insomnia-clinical-aspects-and-molecular-alterations
#1
REVIEW
Franc Llorens, Juan-José Zarranz, Andre Fischer, Inga Zerr, Isidro Ferrer
PURPOSE OF REVIEW: Fatal familiar insomnia (FFI) is an autosomal dominant inherited prion disease caused by D178N mutation in the prion protein gene (PRNP D178N) accompanied by the presence of a methionine at the codon 129 polymorphic site on the mutated allele. FFI is characterized by severe sleep disorder, dysautonomia, motor signs and abnormal behaviour together with primary atrophy of selected thalamic nuclei and inferior olives, and expansion to other brain regions with disease progression...
April 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28315178/a-systematic-review-of-measurement-properties-of-patient-reported-outcome-measures-for-use-in-patients-with-foot-or-ankle-diseases
#2
Yuanxi Jia, Hsiaomin Huang, Joel J Gagnier
PURPOSE: To identify currently available patient-reported outcome measures (PROMs) used in patients with foot or ankle diseases; and to critically appraise, compare and synthesize the psychometric evidence for the identified PROMs. METHODS: Literature searches were performed in Medline and EMBASE from their inception to January 25th, 2016. Methodological quality was evaluated using the COSMIN checklist. The final rating of the methodological quality of each study for each property was the lowest rating among the items within that property...
March 17, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28295468/the-protective-effects-of-a-novel-fitness-fatness-index-on-all-cause-mortality-among-adults-with-cardiovascular-disease
#3
Emily Frith, Paul D Loprinzi
BACKGROUND: We evaluated the specific association between a fitness-fatness index (FFI) and all-cause mortality among a national sample of US adults with coronary artery disease, congestive heart failure, or myocardial infarction. This FFI has recently emerged in the literature as a novel index of health. HYPOTHESIS: We hypothesize that FFI will be inversely associated with mortality risk. METHODS: The FFI was calculated as cardiorespiratory fitness divided by waist-to-height ratio...
March 10, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28294565/ankle-pathologies-in-patients-with-inflammatory-rheumatic-diseases-a-clinical-and-ultrasonographic-study
#4
Halil Harman, İbrahim Tekeoğlu
AIM: We determined ankle pathologies in patients with different types of inflammatory rheumatic diseases using high-resolution ultrasonographic (US) images, and compared the findings among the different patient groups. METHODS: The study included 142 randomly selected inflammatory rheumatic disease patients with clinically swollen or painful ankle joints; 69 patients had rheumatoid arthritis (RA), 58 had spondyloarthropathies (SpA) and 15 had gout. Ankle assessment on US included all of the important anatomical structures...
March 12, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28282069/-burnout-engagement-and-personality-factors-in-medical-students-at-a-public-university
#5
Gladys V Hansen, Marcela D'Urso Villar, Liliana N Fracchia
Medical students can develop burnout syndrome, characterized by exhaustion, cynical attitude towards study and negative consequences on wellbeing and academic performance. Engagement, theoretically syndrome "opposite" to burnout, shows a positive influence on personal and academic performance. To study the association of syndromes burnout and engagement with personality factors in medical students, a longitudinal observational, descriptive study of a cohort follow-up was performed. Three questionnaires were used: reduced inventory NEO Five-Factor (NEO FFI) administered at the beginning of the sixth year; the Maslach Burnout Inventory-Student Survey and Utrecht Work Engagement Scale, applied at the end of the seventh year...
September 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28260642/psychiatric-symptoms-and-response-quality-to-self-rated-personality-tests-evidence-from-the-psycolaus-study
#6
Marc Dupuis, Emanuele Meier, Dominique Rudaz, Marie-Pierre F Strippoli, Enrique Castelao, Martin Preisig, Roland Capel, Caroline L Vandeleur
Despite the fact that research has demonstrated consistent associations between self-rated measures of personality dimensions and mental disorders, little has been undertaken to investigate the relation between psychiatric symptoms and response patterns to self-rated tests. The aim of this study was to investigate the association between psychiatric symptoms and response quality using indices from our functional method. A sample of 1,784 participants from a Swiss population-based cohort completed a personality inventory (NEO-FFI) and a symptom checklist of 90 items (SCL-90-R)...
February 20, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28245006/-burnout-in-officers-of-the-prison-service-units-the-role-of-personality-and-selected-professional-characteristics
#7
Ewa Sygit-Kowalkowska, Magdalena Weber-Rajek, Martyna Herkt, Roman Ossowski
BACKGROUND: The researchers involved in the studies of burnout indicate its 3 sources: the structure of the personality, the specificity of interpersonal relationships, and the organizational factors. The aim of this study was to evaluate the occurrence of burnout and personality characteristics of prison officers, as well as to determine predictors of burnout in this occupational group. MATERIAL AND METHODS: The study was conducted among prison officers, who were divided into 2 groups, the officers working in direct contact with prisoners (group I) and those employed in the prison administration (group II)...
February 28, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28242768/american-orthopaedic-foot-and-ankle-society-aofas-ankle-hindfoot-score-a-study-protocol-for-the-translation-and-validation-of-the-dutch-language-version
#8
Esther M M Van Lieshout, A Siebe De Boer, Duncan E Meuffels, P Ted Den Hoed, Cornelis H Van der Vlies, Wim E Tuinebreijer, Michael H J Verhofstad
INTRODUCTION: The American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score is among the most commonly used instruments for measuring the outcome of treatment in patients who sustained a complex ankle or hindfoot injury. It combines a clinician-reported and a patient-reported part. A valid Dutch version of this instrument is currently not available. Such a translated and validated instrument would allow objective comparison across hospitals or between patient groups, and with shown validity and reliability it may become a quality of care indicator in future...
February 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28223956/the-predictive-value-of-the-neo-ffi-items-parsing-the-nature-of-social-anhedonia-using-the-revised-social-anhedonia-scale-and-the-acips
#9
Diane C Gooding, Emily R Padrutt, Madeline J Pflum
The goal was to examine the nature of social anhedonia using two validated measures and study their relationship to scores on the NEO-Five Factor Inventory (NEO-FFI). Nearly 1,900 college-aged participants completed the Chapman Revised Social Anhedonia Scale (RSAS), Anticipatory and Consummatory Interpersonal Pleasure Scale (ACIPS), and the NEO-FFI. Although both the RSAS and ACIPS were associated with the NEO-FFI domains of Extraversion, Agreeableness, and Neuroticism, linear regression analyses revealed that the RSAS and ACIPS were differentially predicted by NEO-FFI item clusters...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28223952/the-role-of-personality-traits-in-young-adult-fruit-and-vegetable-consumption
#10
Tamlin S Conner, Laura M Thompson, Rachel L Knight, Jayde A M Flett, Aimee C Richardson, Kate L Brookie
This project investigated how individual differences in the big-five personality traits (neuroticism, extraversion, openness to experience, conscientiousness, and agreeableness) predicted plant-food consumption in young adults. A total of 1073 participants from two samples of young adults aged 17-25 reported their daily servings of fruits, vegetables, and two unhealthy foods for comparison purposes using an Internet daily diary for 21 or 13 days (micro-longitudinal, correlational design). Participants also completed the Neuroticism, Extraversion, Openness Five Factor Inventory (NEO-FFI) measure of personality, and demographic covariates including gender, age, ethnicity, and body mass index (BMI)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28211555/personality-traits-level-of-anxiety-and-styles-of-coping-with-stressin-people-with-asthma-and-chronic-obstructive-pulmonary-disease-a-comparative-analysis
#11
Klaudia Tabała, Magdalena Wrzesińska, Patryk Stecz, Józef Kocur
OBJECTIVES: Chronic obstructive pulmonary disease (COPD) and asthma are a challenge to public health, with the sufferers experiencing a range of psychological factors affecting their health and behavior. The aim of the present study was to determine the level of anxiety, personality traits and stress-coping ability of patients with obstructive lung disease and comparison with a group of healthy controls. METHODS: The research was conducted on a group of 150 people with obstructive lung diseases (asthma and COPD) and healthy controls (mean age = 56...
December 23, 2016: Psychiatria Polska
https://www.readbyqxmd.com/read/28210943/faces-of-frailty-in-aging-with-hiv-infection
#12
REVIEW
Marion Thurn, Deborah R Gustafson
PURPOSE OF THE REVIEW: The number of adults who are aging successfully and have HIV infection is increasing. More effective antiretroviral therapy (ART) regimens are preventing individuals infected with HIV from reaching end stages of the HIV infection and developing AIDS (acquired immunodeficiency syndrome). However, even at lower viral loads, chronic HIV infection appears to have consequences on aging processes, including the development of frailty. RECENT FINDINGS: Frailty is a term used to describe vulnerability in aging...
February 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/28199069/adding-clinical-validity-to-the-statistical-power-of-large-scale-epidemiological-surveys-on-internet-addiction-in-adolescence-a-combined-approach-to-investigate-psychopathology-and-development-specific-personality-traits-associated-with-internet-addiction
#13
Kai W Müller, Michael Dreier, Eva Duven, Sebastian Giralt, Manfred E Beutel, Klaus Wölfling
OBJECTIVE: Research has indicated that internet addiction is associated with psychosocial maladjustment in adolescence. Many epidemiologic surveys are lacking representativeness, and knowledge on disorder-specific risk factors is scarce. One weakness of epidemiologic studies often regards their lack of generalizability to clinical reality. The aim of this study was to provide a detailed description of internet addiction among adolescents, focusing on its prevalence in a population-based context, psychopathological correlates, and predisposing factors...
February 14, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28187122/overt-and-covert-anxiety-as-a-toxic-factor-in-ischemic-heart-disease-in-women-the-link-between-psychological-factors-and-heart-disease
#14
Alicja Nasiłowska-Barud, Tomasz Zapolski, Małgorzata Barud, Andrzej Wysokiński
BACKGROUND Long-term clinical observations have shown that anxiety disorders influence the etiopathogenesis of ischemic heart disease (IHD) in women. The aim of this study was to determine the characteristics of the structure of overt and covert anxiety, and to examine the impact of the severity of anxiety on five personality traits as described Costa and McCrae. MATERIAL AND METHODS The study involved 50 women aged 37 to 74 years, who were treated because of IHD that was confirmed by angiographic examination of the coronary vessels...
February 10, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28178272/psychobiological-factors-affecting-cortisol-variability-in-human-dog-dyads
#15
Iris Schöberl, Manuela Wedl, Andrea Beetz, Kurt Kotrschal
Stress responses within dyads are modulated by interactions such as mutual emotional support and conflict. We investigated dyadic psychobiological factors influencing intra-individual cortisol variability in response to different challenging situations by testing 132 owners and their dogs in a laboratory setting. Salivary cortisol was measured and questionnaires were used to assess owner and dog personality as well as owners' social attitudes towards the dog and towards other humans. We calculated the individual coefficient of variance of cortisol (iCV = sd/mean*100) over the different test situations as a parameter representing individual variability of cortisol concentration...
2017: PloS One
https://www.readbyqxmd.com/read/28177178/association-of-premorbid-personality-with-behavioral-and-psychological-symptoms-in-dementia-with-lewy-bodies-comparison-with-alzheimer-s-disease-patients
#16
Kazuki Tabata, Yasuaki Saijo, Fumiyoshi Morikawa, Juichiro Naoe, Eiji Yoshioka, Yasuyuki Kawanishi, Yoshihiko Nakagi, Takahiko Yoshida
AIM: The aim of this study was to elucidate the relationship between premorbid personality traits and behavioral and psychological symptoms in dementia (BPSD) in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) patients. METHODS: Forty-one DLB patients and 98 AD patients were assessed for BPSD using the Neuropsychiatric Inventory (NPI). Each patient's midlife personality traits were rated by a family member using the NEO Five-Factor Inventory (NEO-FFI) questionnaire...
February 8, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28161654/the-burden-of-conscientiousness-examining-brain-activation-and-cortisol-response-during-social-evaluative-stress
#17
Anne-Sophie Dahm, Phöbe Schmierer, Ilya M Veer, Fabian Streit, Anna Görgen, Johann Kruschwitz, Stefan Wüst, Peter Kirsch, Henrik Walter, Susanne Erk
Although conscientiousness has for a long time been considered generally adaptive, there are findings challenging this view, suggesting that conscientiousness might be less advantageous during uncontrollable stress. We here examined the impact of conscientiousness on brain activation during and the cortisol response following an uncontrollable social evaluative stress task in order to test this hypothesis. Brain activation and cortisol levels were measured during an fMRI stress task, where subjects (n=86) performed cognitive tasks containing preprogrammed failure under time pressure, while being monitored by a panel of experts inducing social-evaluative threat...
January 23, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28149661/biomechanical-podiatric-evaluation-in-an-italian-cohort-of-patients-with-systemic-sclerosis-a-pilot-study
#18
Susanna Maddali Bongi, Giovanni Ravenni, Benedetta Ciampi, Angela Del Rosso, Khadija El Aoufy
OBJECTIVE: Foot problems are often present in Systemic Sclerosis (SSc) patients, however studies regarding podiatric problems related to SSc are lacking and there are no data evaluating the foot biomechanical changes. The aim of the present pilot study was to evaluate podiatric problems in an Italian cohort of SSc patients by assessing received podiatric services, foot pain and disability and biomechanical foot deformity. MATERIAL AND METHODS: 25 consecutive SSc patients were enrolled from the Division of Rheumatology, University of Florence...
December 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28106551/conscientiousness-is-negatively-associated-with-grey-matter-volume-in-young-apoe%C3%A9-4-carriers
#19
Lukas Kunz, Martin Reuter, Nikolai Axmacher, Christian Montag
The etiology of late onset Alzheimer's disease (LOAD) depends on multiple factors, among which the APOEɛ4 allele is the most adverse genetic determinant and conscientiousness represents an influential personality trait. A potential association of both factors with brain structure in young adulthood may constitute a constellation that sets the course toward or against the subtle disease progression of LOAD that starts decades before clinical manifestation. Hence, in the present study, we examined the modulating effects of APOEɛ4 on the relation between personality dimensions, including conscientiousness, and total grey matter volume (GMV) in young healthy adults using an a priori genotyping design...
January 18, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28103153/agreeableness-and-pregnancy-relations-with-coping-and-psychiatric-symptoms-a-longitudinal-study-on-spanish-pregnant-women
#20
Cecilia Peñacoba, Laura Rodríguez, Javier Carmona, Dolores Marín
Agreeableness is associated with good mental health during pregnancy. Although different studies have indicated that agreeableness is related to adaptive coping, this relation has scarcely been studied in pregnant women. The aim of this study was to analyze the possible differences between high and low agreeableness in relation to coping strategies and psychiatric symptoms in pregnant women. We conducted a longitudinal prospective study between October 2009 and January 2013. Pregnant women (n = 285) were assessed in the first trimester of pregnancy, and 122 of them were assessed during the third...
January 19, 2017: Women & Health
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