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Early Childhood Development

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https://www.readbyqxmd.com/read/29158765/usefulness-of-the-korean-developmental-screening-test-for-infants-and-children-for-the-evaluation-of-developmental-delay-in-korean-infants-and-children-a-single-center-study
#1
Chung-Hyuk Yim, Gun-Ha Kim, Baik-Lin Eun
Purpose: To evaluate the usefulness of the Korean Developmental Screening Test (K-DST) for infants and children for developmental delay assessment. Methods: This study was based on retrospective studies of the results of the K-DST, Preschool Receptive-Expressive Language Scale (PRES), Sequenced Language Scale for Infants (SELSI), Childhood Autism Rating Scale (CARS), Modified Checklist for Autism in Toddlers (M-CHAT), electroencephalography, magnetic resonance imaging, and extensive tests conducted in 209 of 1,403 patients, of whom 758 underwent the K-DST at the Korea University Guro Hospital between January 2015 and December 2016 and 645 were referred from local clinics between January 2015 and June 2016...
October 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29157671/infectious-agents-in-childhood-leukemia
#2
REVIEW
José Arellano-Galindo, Alberto Parra Barrera, Elva Jiménez-Hernández, Sergio Zavala-Vega, Guillermina Campos-Valdéz, Juan Xicohtencatl-Cortes, Sara A Ochoa, Ariadnna Cruz-Córdova, María Del Pilar Crisóstomo-Vázquez, Juan Carlos Fernández-Macías, Juan Manuel Mejía-Aranguré
Acute leukemia is the most common pediatric cancer, representing one-third of all cancers that occurs in under 15 year olds, with a varied incidence worldwide. Although a number of advances have increased the knowledge of leukemia pathophysiology, its etiology remains less well understood. The role of infectious agents, such as viruses, bacteria, or parasites, in the pathogenesis of leukemia has been discussed. To date, several cellular mechanisms involving infectious agents have been proposed to cause leukemia following infections...
May 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/29157486/nouveaut%C3%A3-s-dans-l%C3%A2-hyperplasie-cong%C3%A3-nitale-des-surr%C3%A3-nales-new-insights-in-congenital-adrenal-hyperplasia
#3
L Dumeige, C Bouvattier, M Lombès
Congenital adrenal hyperplasia is an autosomal recessive disease due to functional abnormalities of adrenal steroid enzymes. The most common form of the disease is due to a 21-hydroxylase deficiency. The classical forms (most severe) are characterized by a deficiency in cortisol and sometimes in aldosterone, which may compromise the vital prognosis of neonates, and by an increase in androgen synthesis, leading to the virilization of girls' external genitalia at birth, followed by clinical signs of hyperandrogenism during childhood and adolescence...
October 2017: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29156943/assessment-of-biochemical-bone-turnover-markers-and-bone-mineral-density-in-thin-and-normal-weight-children
#4
Jadwiga Ambroszkiewicz, Joanna Gajewska, Grazyna Rowicka, Witold Klemarczyk, Magdalena Chelchowska
Objective There is scant research examining the prevalence of thinness in early childhood, despite its potential negative consequences for health and development across the life course. The objective of this study was to assess bone status through measurement of bone mineral density and biochemical bone turnover markers, with special attention paid to carboxylated (c-OC) as well as undercarboxylated (uc-OC) forms of osteocalcin, in the groups of thin and normal-weight children. Design The study included 80 healthy prepubertal children (median age 7...
January 1, 2017: Cartilage
https://www.readbyqxmd.com/read/29156925/-new-ingredients-in-infant-formula-health-and-functional-benefits
#5
M Cristina De Almagro García, José Antonio Moreno Muñoz, Jesús Jiménez López, María Rodríguez-Palmero Seuma
There is an increasing body of evidence about the effect that early nutrition and lifestyle could have on the programming of later health and disease. Infant formula must cover all the nutritional needs to promote adequate infant growth and development. Currently, important research efforts have been made to supplement infant formulae with new bioactive ingredients with health benefits for the infant. The milk fat globule membrane is one of the new ingredients, which provides phospholipids and gangliosides, as well as bioactive proteins...
October 15, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29155486/toxic-stress-and-child-refugees
#6
John S Murray
The purpose of this article was to describe the phenomenon of toxic stress and its impact on the physical and mental health of child refugees. Almost two decades ago, researchers found that recurring adverse childhood events (ACEs; e.g., physical, psychological, and sexual abuse, neglect, and household dysfunction such as substance abuse, mental illness, and criminal behavior) were associated with a significant increase in serious illnesses during adulthood. Illnesses include heart, lung, and liver disease, cancer, and bone fractures...
November 20, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/29155118/patterns-of-neuroendocrine-coupling-in-9-year-old-children-effects-of-sex-body-mass-index-and-life-stress
#7
Sarah R Black, Matthew D Lerner, Elizabeth A Shirtcliff, Daniel N Klein
Previous investigations have explored stress and pubertal hormones in parallel; it has been a recent development, however, to explore the relationships between different hormones during puberty, and how this hormonal cross-talk may be influenced by the environment. The current study investigated neuroendocrine coupling, or the extent to which hormones are correlated within the individual, and also investigated early life stressors that may influence coupling. Participants were 405 adrenarcheal children (mean Tanner stage=1...
November 16, 2017: Biological Psychology
https://www.readbyqxmd.com/read/29154959/early-life-innate-immune-signatures-of-persistent-food-allergy
#8
Melanie R Neeland, Jennifer J Koplin, Thanh D Dang, Shyamali C Dharmage, Mimi L Tang, Susan L Prescott, Richard Saffery, David J Martino, Katrina J Allen
BACKGROUND: Food allergy naturally resolves in a proportion of food allergic children without intervention, however the underlying mechanisms governing the persistence or resolution of food allergy in childhood are not understood. OBJECTIVES: This study aimed to define the innate immune profiles associated with egg allergy at one year of age, determine the phenotypic changes that occur with the development of natural tolerance in childhood and explore the relationship between early life innate immune function and serum vitamin D...
November 14, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29154930/suicide-attempts-in-children-and-adolescents-the-place-of-clock-genes-and-early-rhythm-dysfunction
#9
Bertrand Olliac, Lisa Ouss, Annaëlle Charrier
Suicide remains one of the leading causes of death among young people, and suicidal ideation and behavior are relatively common in healthy and clinical populations. Suicide risk in childhood and adolescence is often approached from the perspective of nosographic categories to which predictive variables for suicidal acts are often linked. The cascading effects resulting from altered clock genes in a pediatric population could participate in biological rhythm abnormalities and the emergence of suicide attempts through impaired regulation of circadian rhythms and emotional states with neurodevelopmental effects...
November 14, 2017: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/29154791/associations-of-early-life-urinary-triclosan-concentrations-with-maternal-neonatal-and-child-thyroid-hormone-levels
#10
Joseph M Braun, Aimin Chen, Andrew Hoofnagle, George D Papandonatos, Medina Jackson-Browne, Russ Hauser, Megan E Romano, Margaret R Karagas, Kimberly Yolton, R Thomas Zoeller, Bruce P Lanphear
BACKGROUND: Triclosan, an antimicrobial agent used in some consumer products, reduces endogenous thyroid hormone concentrations in rodents. Despite ubiquitous triclosan exposure and the importance of thyroid hormones for normal fetal development, few human studies have examined the impact of triclosan exposure on maternal, neonatal, or child thyroid hormones. METHODS: In the HOME Study, a prospective cohort from Cincinnati, OH, we measured urinary triclosan concentrations up to three times in pregnant women between 16weeks and delivery, and up to three times in children between age 1-3years...
November 14, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/29154657/trajectories-of-parental-engagement-in-early-childhood-among-dual-earner-families-effects-on-child-self-control
#11
Tiago Ferreira, Joana Cadima, Marisa Matias, Joana Marina Vieira, Teresa Leal, Karine Verschueren, Paula Mena Matos
Parental engagement in positive activities with the child may show significant variation across time, assuming a crucial influence on child development. In dual-earner families, work-family conflict can interfere with parental engagement, with negative consequences for children's behavior. The current study examined the change trajectories of mothers' and fathers' engagement in early childhood, analyzing whether these trajectories are influenced by parents' work-family conflict and whether they predict child behavioral self-control...
November 20, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/29154030/perceptual-completion-of-partly-occluded-contours-during-childhood
#12
Bat Sheva Hadad, Ruth Kimchi
An early functional onset of perceptual completion has been extensively documented during the first several months after birth. However, there is no indication for the developmental time periods at which these skills become fully developed. We used a version of an object-based attention task in which children and adults performed a same-different size judgment of two features appearing at two of four possible ends of overlapping objects. Single-object over two-object superiority (i.e., faster judgments when the features appeared on the same object than when they appeared on different objects) was observed for a complete object as early as at 4 years of age...
November 16, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29153880/food-allergy-is-an-important-risk-factor-for-childhood-asthma-irrespective-of-whether-it-resolves
#13
Evelien M Vermeulen, Jennifer J Koplin, Shyamali C Dharmage, Lyle C Gurrin, Rachel L Peters, Vicki McWilliam, Anne-Louise Ponsonby, Terence Dwyer, Adrian J Lowe, Mimi L K Tang, Katrina J Allen
BACKGROUND: The risk of developing asthma in those with early food allergy is unknown, particularly when early life food allergy has resolved. OBJECTIVE: To understand whether challenge-proven food allergy in infancy increases the risk of asthma at age 4 years, using data from a population-based cohort. METHODS: A total of 5,276 12-month-old infants were recruited using a population-based sampling frame. Infants underwent skin prick test to egg, peanut, and sesame and those with a detectable skin prick test result had oral food challenges...
November 15, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29153316/investment-in-child-and-adolescent-health-and-development-key-messages-from-disease-control-priorities-3rd-edition
#14
REVIEW
Donald A P Bundy, Nilanthi de Silva, Susan Horton, George C Patton, Linda Schultz, Dean T Jamison
The realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence. Focus on the first 1000 days is an essential but insufficient investment. Intervention is also required in three later phases: the middle childhood growth and consolidation phase (5-9 years), when infection and malnutrition constrain growth, and mortality is higher than previously recognised; the adolescent growth spurt (10-14 years), when substantial changes place commensurate demands on good diet and health; and the adolescent phase of growth and consolidation (15-19 years), when new responses are needed to support brain maturation, intense social engagement, and emotional control...
November 16, 2017: Lancet
https://www.readbyqxmd.com/read/29152992/the-levels-of-physical-activity-and-motor-skills-in-young-children-with-and-without-autism-spectrum-disorder-aged-2-5-years
#15
Leah Ketcheson, Janet Lynn Hauck, Dale Ulrich
Autism spectrum disorder is the fastest growing developmental disability in the United States. As such, there is an unprecedented need for research examining factors contributing to the health disparities in this population. This research suggests a relationship between the levels of physical activity and health outcomes. In fact, excessive sedentary behavior during early childhood is associated with a number of negative health outcomes. A total of 53 children participated in this study, including typically developing children (mean age = 42...
March 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29152164/mutations-in-rab39b-in-individuals-with-intellectual-disability-autism-spectrum-disorder-and-macrocephaly
#16
Marc Woodbury-Smith, Eric Deneault, Ryan K C Yuen, Susan Walker, Mehdi Zarrei, Giovanna Pellecchia, Jennifer L Howe, Ny Hoang, Mohammed Uddin, Christian R Marshall, Christina Chrysler, Ann Thompson, Peter Szatmari, Stephen W Scherer
Background: Autism spectrum disorder (ASD), a developmental disorder of early childhood onset, affects males four times more frequently than females, suggesting a role for the sex chromosomes. In this study, we describe a family with ASD in which a predicted pathogenic nonsense mutation in the X-chromosome gene RAB39B segregates with ASD phenotype. Methods: Clinical phenotyping, microarray, and whole genome sequencing (WGS) were performed on the five members of this family...
2017: Molecular Autism
https://www.readbyqxmd.com/read/29151660/neighbourhood-ethnic-density-effects-on-behavioural-and-cognitive-problems-among-young-racial-ethnic-minority-children-in-the-us-and-england-a-cross-national-comparison
#17
Nan Zhang, Jennifer L Beauregard, Michael R Kramer, Laia Bécares
Studies on adult racial/ethnic minority populations show that the increased concentration of racial/ethnic minorities in a neighbourhood-a so-called ethnic density effect-is associated with improved health of racial/ethnic minority residents when adjusting for area deprivation. However, this literature has focused mainly on adult populations, individual racial/ethnic groups, and single countries, with no studies focusing on children of different racial/ethnic groups or comparing across nations. This study aims to compare neighbourhood ethnic density effects on young children's cognitive and behavioural outcomes in the US and in England...
2017: Population Research and Policy Review
https://www.readbyqxmd.com/read/29151377/early-childhood-parenting-and-child-impulsivity-as-precursors-to-aggression-substance-use-and-risky-sexual-behavior-in-adolescence-and-early-adulthood
#18
Rochelle F Hentges, Daniel S Shaw, Ming-Te Wang
The current study utilized a longitudinal design to explore the effect of early child impulsivity and rejecting parenting on the development of problematic behaviors in adolescence and early adulthood. Using a low-income sample of 310 mothers and their sons, we examined the direct and interactive effects of child impulsivity and rejecting parenting at age 2 on aggression and substance use at ages 12, 15, and 22, as well as risky sexual behavior at ages 15 and 22. Results revealed that rejecting parenting at age 2 predicted greater aggression at age 12 and risky sexual behavior at ages 15 and 22...
November 20, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29148828/increased-cellular-aging-by-3-years-of-age-in-latino-preschool-children-who-consume-more-sugar-sweetened-beverages-a-pilot-study
#19
Janet M Wojcicki, Rosalinda Medrano, Jue Lin, Elissa Epel
BACKGROUND: Previous studies in adults and older children find that sugar-sweetened beverage (SSB) consumption increases risk for obesity and cellular aging, as measured by leukocyte telomere length (LTL). METHODS: In a previously described, San Francisco-based Latino birth cohort, where telomere length was measured at birth, we evaluate the relationship between beverage consumption (including SSB and 100% fruit juice), obesity, and LTL at 2-3 years old, as well as change in LTL from birth...
November 17, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/29147750/the-association-between-childhood-fractures-and-adolescence-bone-outcomes-a-population-based-study-the-troms%C3%A3-study-fit-futures
#20
T Christoffersen, N Emaus, E Dennison, A-S Furberg, L Gracia-Marco, G Grimnes, O A Nilsen, D Vlachopoulos, A Winther, L A Ahmed
Childhood fracture may predict persistent skeletal fragility, but it may also reflect high physical activity which is beneficial to bone development. We observe a difference in the relationship between previous fracture and bone outcome across physical activity level and sex. Further elaboration on this variation is needed. PURPOSE: Childhood fracture may be an early marker of skeletal fragility, or increased levels of physical activity (PA), which are beneficial for bone mineral accrual...
November 16, 2017: Osteoporosis International
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