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Early Childhood Development

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https://www.readbyqxmd.com/read/27915378/mother-infant-interactions-and-regional-brain-volumes-in-infancy-an-mri-study
#1
Vaheshta Sethna, Inês Pote, Siying Wang, Maria Gudbrandsen, Anna Blasi, Caroline McCusker, Eileen Daly, Emily Perry, Kerrie P H Adams, Maria Kuklisova-Murgasova, Paula Busuulwa, Sarah Lloyd-Fox, Lynne Murray, Mark H Johnson, Steven C R Williams, Declan G M Murphy, Michael C Craig, Grainne M McAlonan
It is generally agreed that the human brain is responsive to environmental influences, and that the male brain may be particularly sensitive to early adversity. However, this is largely based on retrospective studies of older children and adolescents exposed to extreme environments in childhood. Less is understood about how normative variations in parent-child interactions are associated with the development of the infant brain in typical settings. To address this, we used magnetic resonance imaging to investigate the relationship between observational measures of mother-infant interactions and regional brain volumes in a community sample of 3- to 6-month-old infants (N = 39)...
December 3, 2016: Brain Structure & Function
https://www.readbyqxmd.com/read/27913907/development-of-a-culturally-informed-child-safety-curriculum-for-american-indian-families
#2
Ryan M Berns, Emily J Tomayko, Kate A Cronin, Ronald J Prince, Tassy Parker, Alexandra K Adams
American Indian (AI) children are disproportionately affected by unintentional injuries, with injury mortality rates approximately 2.3 times higher than the combined rates for all children in the United States. Although multiple risk factors are known to contribute to these increased rates, a comprehensive, culturally informed curriculum that emphasizes child safety is lacking for this population. In response to this need, academic and tribal researchers, tribal community members, tribal wellness staff, and national child safety experts collaborated to develop a novel child safety curriculum...
December 2, 2016: Journal of Primary Prevention
https://www.readbyqxmd.com/read/27911083/nonlinear-growth-models-as-measurement-models-a-second-order-growth-curve-model-for-measuring-potential
#3
Daniel McNeish, Denis Dumas
Recent methodological work has highlighted the promise of nonlinear growth models for addressing substantive questions in the behavioral sciences. In this article, we outline a second-order nonlinear growth model in order to measure a critical notion in development and education: potential. Here, potential is conceptualized as having three components-ability, capacity, and availability-where ability is the amount of skill a student is estimated to have at a given timepoint, capacity is the maximum amount of ability a student is predicted to be able to develop asymptotically, and availability is the difference between capacity and ability at any particular timepoint...
December 2, 2016: Multivariate Behavioral Research
https://www.readbyqxmd.com/read/27908895/childhood-maltreatment-and-characteristics-of-adult-depression-meta-analysis
#4
REVIEW
Janna Nelson, Anne Klumparendt, Philipp Doebler, Thomas Ehring
BACKGROUND: Childhood maltreatment has been discussed as a risk factor for the development and maintenance of depression. AIMS: To examine the relationship between childhood maltreatment and adult depression with regard to depression incidence, severity, age at onset, course of illness and treatment response. METHOD: We conducted meta-analyses of original articles reporting an association between childhood maltreatment and depression outcomes in adult populations...
December 1, 2016: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/27908434/an-observational-study-of-handwashing-compliance-in-a-child-care-facility
#5
Jeffrey Clark, Jennifer K Henk, Philip G Crandall, Mardel A Crandall, Corliss A O'Bryan
BACKGROUND: Handwashing (HW) compliance, although an effective means of limiting childhood illness, remains low among personnel in early childhood centers (ECCs). Our study determined HW compliance and efficacy of ECC personnel. METHODS: Surveillance cameras were used to determine HW opportunities, compliance, occurrences, and effectiveness based on child-care oriented criteria. RESULTS: We observed 349 HW triggering events, with 14 events per hour; a median of 2 personnel (caregivers, paraprofessional aides, or parents) were present at any given time period...
December 1, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27907833/development-of-a-scale-to-evaluate-young-children-s-responses-to-uncertainty-and-low-environmental-structure
#6
Amanda L Sanchez, Danielle Cornacchio, Tommy Chou, Ovsanna Leyfer, Stefany Coxe, Donna Pincus, Jonathan S Comer
Intolerance of Uncertainty (IU), defined as the dispositional interpretation of uncertain or ambiguous events as stressful and problematic, has been linked to excessive worry and other anxiety-related problems in adults and youth. IU has been conceptualized as a vulnerability factor for excessive worry and anxiety, but the historical absence of a supported measure of IU in young children has hampered longitudinal research needed to evaluate temporal relationships between IU and anxiety and the differential developmental pathways of IU leading to different anxiety disorders and depression...
November 21, 2016: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/27907230/reverse-geroscience-how-does-exposure-to-early-diseases-accelerate-the-age-related-decline-in-health
#7
Ronald A Kohanski, Steven G Deeks, Claudia Gravekamp, Jeffrey B Halter, Kevin High, Arti Hurria, Rebecca Fuldner, Paige Green, Robin Huebner, Francesca Macchiarini, Felipe Sierra
Aging is the major risk factor for both the development of chronic diseases and loss of functional capacity. Geroscience provides links among the biology of aging, the biology of disease, and the physiology of frailty, three fields where enormous progress has been made in the last few decades. While, previously, the focus was on the role of aging in susceptibility to disease and disability, the other side of this relationship, which is the contribution of disease to aging, has been less explored at the molecular/cellular level...
December 1, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27906088/folie-%C3%A3-deux-and-its-interaction-with-early-life-stress-a-case-report
#8
Alessandra Vargas Alves Nunes, Sandra Odebrecht Vargas Nunes, Talita Strano, Gilberto Pascolat, Gustavo Manoel Schier Doria, Mauricio Nasser Ehlke
BACKGROUND: Folie à deux is a very rare psychiatric syndrome in which a psychotic symptom is transmitted from one individual to another. We present a case of folie à deux occurring during childhood, which is not an usual presentation of this syndrome. In this case, the disorder is correlated with child abuse and neglect, which possibly had a role in the development of the symptoms in our case. CASE PRESENTATION: We present a case of folie à deux between an "induced" 9-year-old black Brazilian boy and the "inducer", his grandmother...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27905923/navigating-the-journey-of-aboriginal-childhood-disability-a-qualitative-study-of-carers-interface-with-services
#9
Anna Green, Penelope Abbott, Patricia Delaney, Patrick Patradoon-Ho, John Delaney, Patricia Mary Davidson, Michelle DiGiacomo
BACKGROUND: The disadvantage experienced by Aboriginal and Torres Strait Islander children with a disability is well recognized. The long term consequences of failing to address disability on health, education and employment underlies the importance of early intervention. Caregivers experience a disproportionate burden and have challenges accessing services. The aim of this study was to describe the carer journey of accessing support and services. METHODS: We conducted in-depth semi-structured interviews with nineteen parents and carers of Aboriginal children aged 0-8 years...
December 1, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27904026/inverse-relationship-between-sleep-duration-and-cardio-ankle-vascular-index-in-children
#10
Noriteru Morita, Isao Kambayashi, Tomoyasu Okuda, Shiro Oda, Shingo Takada, Toshihiro Nakajima, Noriyuki Shide, Hisashi Shinkaiya, Koichi Okita
AIM: Poor sleep has been shown to be associated with the development of cardiovascular risk factors, such as obesity, in both adults and children. This study aimed to investigate the relationship between sleep duration and arterial stiffness indices in Japanese children and early adolescents. METHODS: The data on 102 students (56 males, 46 females; mean age, 11.9±1.8 years) were analyzed. As non-invasive arterial stiffness parameters, the cardio-ankle vascular index (CAVI) and heart-ankle pulse wave velocity (haPWV) were evaluated...
December 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27903593/respiratory-syncytial-virus-infection-detection-and-new-options-for-prevention-and-treatment
#11
REVIEW
Cameron Griffiths, Steven J Drews, David J Marchant
Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children in North America and one of the leading causes of death of infants less than 1 year of age worldwide, second only to malaria. Despite its global impact on human health, there are relatively few therapeutic options available to prevent or treat RSV infection. Paradoxically, there is a very large volume of information that is constantly being refined on RSV replication, the mechanisms of RSV-induced pathology, and community transmission...
January 2017: Clinical Microbiology Reviews
https://www.readbyqxmd.com/read/27900941/the-kidney-in-sickle-hemoglobinopathies%C3%A2
#12
Medha Airy, Garabed Eknoyan
With improvements in the care of patients with sickle hemoglobinopathies, sickle cell disease (SCD) has evolved from a disease that was fatal in childhood into one in which most survive past their 5th decade and some into old age. As a result, the renal complications of sickle hemoglobinopathies, which are age dependent, have emerged as a common and serious complication of SCD. Approximately 14 - 18% of mortality in SCD is attributed to chronic kidney disease (CKD), which develops in 1/3 of individuals with SCD and progresses to end-stage renal disease in 4 - 18% of them...
November 30, 2016: Clinical Nephrology
https://www.readbyqxmd.com/read/27900154/efficacy-of-gross-motor-skill-interventions-in-young-children-an-updated-systematic-review
#13
Sanne L C Veldman, Rachel A Jones, Anthony D Okely
OBJECTIVE: The objective of this study was to provide an update of the evidence on the efficacy of gross motor development interventions in young children (0-5 years) from 2007 to 2015. METHODS: Searches were conducted of six electronic databases: PUBMED, Medline (Ovid), ERIC (Ebsco), Embase, SCOPUS and Psychinfo. Studies included any childcare-based, preschool-based, home-based, or community-based intervention targeting the development of gross motor skills including statistical analysis of gross motor skill competence...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27899439/a-community-arts-based-parent-program
#14
Julia Richerson, Amber Pendleton, Deborah Winders Davis
Early childhood is an important period for development. Parents play an important role in structuring children's physical and psychosocial environments. Much remains unknown about the best methods for engaging parents in health promotion programs. It is critical that programs meet the needs of the families while encouraging the use of positive parenting strategies. The article describes how one pediatrician used the American Academy of Pediatrics' Community Access to Child Health grant program to develop and implement The Arts of Parenting program with input from predominantly low-income families...
November 29, 2016: Clinical Pediatrics
https://www.readbyqxmd.com/read/27899160/physiopathology-of-vesico-ureteral-reflux
#15
REVIEW
Salvatore Arena, Roberta Iacona, Pietro Impellizzeri, Tiziana Russo, Lucia Marseglia, Eloisa Gitto, Carmelo Romeo
Vescico-Ureteral Reflux (VUR) is a common condition in childhood, caused by a congenital anomaly at the Vescico-Ureteral Junction (VUJ) level. It seems that the main cause could be an abnormal embryological development occurred during the early stage of fetal life.Refluxing ureteral endings show structural and functional anomalies: previous studies have shown a significant decrease in alfa actin, miosin and desmin contents as well as an high rate of atrophy and muscular degeneration with disorganized muscular fibres...
November 29, 2016: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/27898075/maternal-high-fat-diet-prevents-developmental-programming-by-early-life-stress
#16
M Rincel, A L Lépinay, P Delage, J Fioramonti, V S Théodorou, S Layé, M Darnaudéry
Anxiety disorders and depression are well-documented in subjects exposed to adverse childhood events. Recently, maternal obesity and/or maternal consumption of high-fat diets (HFD) have been also proposed as risk factors for offspring mental health. Here using an animal model in rats, we explored the combinatorial effects of a maternal HFD (40% of energy from fat without impact on maternal weight; during gestation and lactation) and maternal separation (MS) in offspring. In the prefrontal cortex (PFC) of pups, MS led to changes in the expression of several genes such as Bdnf (brain derived neurotrophic factor), 5HT-r1a (serotonin receptor 1a) and Rest4 (neuron-restrictive silencer element, repressor element 1, silencing transcription factor (Rest), splicing variant 4)...
November 29, 2016: Translational Psychiatry
https://www.readbyqxmd.com/read/27896784/ocular-involvement-associated-with-varicella-in-adults
#17
Salma Gargouri, Sana Khochtali, Sourour Zina, Molka Khairallah, Imen Zone-Abid, Imen Kaibi, Salim Ben Yahia, Jamel Feki, Moncef Khairallah
BACKGROUND: Varicella is a common infectious disease primarily of childhood that is usually benign and self-limited. It is, however, increasingly seen in adults who are at a higher risk of severe infection. Ocular complications of varicella are relatively uncommon and have been rarely described in adults. We describe herein five adults who developed ocular involvement in association with primary varicella-zoster virus infection. FINDINGS: Ocular manifestations included acute anterior uveitis in four eyes, with associated stromal keratitis in one of them, epithelial ulcerative keratitis in the two eyes of one patient, and acute retinal necrosis in one eye...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27896283/a-potential-founder-variant-in-carmil2-rltpr-in-three-norwegian-families-with-warts-molluscum-contagiosum-and-t-cell-dysfunction
#18
Hanne S Sorte, Liv T Osnes, Børre Fevang, Pål Aukrust, Hans C Erichsen, Paul H Backe, Tore G Abrahamsen, Ole B Kittang, Torstein Øverland, Shalini N Jhangiani, Donna M Muzny, Magnus D Vigeland, Pubudu Samarakoon, Tomasz Gambin, Zeynep H C Akdemir, Richard A Gibbs, Olaug K Rødningen, Robert Lyle, James R Lupski, Asbjørg Stray-Pedersen
BACKGROUND: Four patients from three Norwegian families presented with a common skin phenotype of warts, molluscum contagiosum, and dermatitis since early childhood, and various other immunological features. Warts are a common manifestation of human papilloma virus (HPV), but when they are overwhelming, disseminated and/or persistent, and presenting together with other immunological features, a primary immunodeficiency disease (PIDD) may be suspected. METHODS AND RESULTS: The four patients were exome sequenced as part of a larger study for detecting genetic causes of primary immunodeficiencies...
November 2016: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/27895690/rhinovirus-and-childhood-asthma-an-update
#19
REVIEW
Dae Jin Song
Asthma is recognized as a complex disease resulting from interactions between multiple genetic and environmental factors. Accumulating evidence suggests that respiratory viral infections in early life constitute a major environmental risk factor for the development of childhood asthma. Respiratory viral infections have also been recognized as the most common cause of asthma exacerbation. The advent of molecular diagnostics to detect respiratory viruses has provided new insights into the role of human rhinovirus (HRV) infections in the pathogenesis of asthma...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27894371/pervasive-influence-of-maternal-and-paternal-criminal-offending-on-early-childhood-development-a-population-data-linkage-study
#20
K R Laurens, S Tzoumakis, M Kariuki, M J Green, M Hamde, F Harris, V J Carr, K Dean
BACKGROUND: Parental criminal offending is an established risk factor for offending among offspring, but little evidence is available indicating the impact of offending on early childhood functioning. We used data from a large Australian population cohort to determine associations between exposure to parental offending and a range of developmental outcomes at age 5 years. METHOD: Multi-generation data in 66 477 children and their parents from the New South Wales Child Development Study were combined using data linkage...
November 29, 2016: Psychological Medicine
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