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Walid Osman, Zeineb Alaya, Hamdi Kaziz, Lassad Hassini, Meriem Braiki, Nader Naouar, Mohamed Laaziz Ben Ayeche
The management of high-energy pilon fractures is still controversial. Open reduction and internal fixation are often associated with serious complications. Various methods have been used to treat these injuries, with variable results. The aim of this retrospective study was to analyze the clinical and radiographic outcome of the ILIZAROV technique in patients with high-energy pilon fractures. Thirty cases of distal tibia epiphysis fractures (pilon fractures) were managed from 1999 to 2012. The study group included 5 cases of open fractures...
2017: Pan African Medical Journal
Yan Huang, Chengtie Wu, Xiaoling Zhang, Jiang Chang, Kerong Dai
Silicate bioceramics have been considered to possess a wide prospect of clinical application for orthopedic tissue regeneration due to their excellent osteogenesis and angiogenesis. However, the mechanism for silicate bioceramics stimulating bone formation is not fully understood. The host immune defense to implants is proved to greatly influence the osteogenesis and new bone formation, but up to now, few studies are focused on the silicate bioceramics modulated host immune responses. In our present study, two representative silicate bioceramics, akermanite (AKT) and nagelschmidtite (NAGEL) were used as model materials to investigate the inflammation responses in vitro and in vivo, and β-tricalcium phosphate (β-TCP) bioceramics were used as a control...
January 15, 2018: Acta Biomaterialia
Guoxin Fan, Teng Wang, Shuo Hu, Xiaofei Guan, Xin Gu, Shisheng He
BACKGROUND: Accurate puncture during percutaneous transforaminal endoscopic discectomy at the L5/S1 level in cases with high iliac crest and narrow foramen were difficult, even though the difficulties of foraminoplasty could be overcome by advanced instruments like reamers. OBJECTIVES: The report aimed to describe an isocentric navigation technique with a definite pathway in difficult puncture cases at the L5/S1 level. STUDY DESIGN: Technical note...
May 2017: Pain Physician
Kristen Nicholson, Nancy Lennon, Robert Hulbert, Chris Church, Freeman Miller
BACKGROUND: No data are available regarding level of walking activity for youth with cerebral palsy (CP) before undergoing orthopeadic surgery. The goals of this study were to quantify pre-operative walking activity, and determine whether pre-operative values are different from previously defined levels of walking activity in youth with CP. PROCEDURES: This study retrospectively evaluated pre-operative walking activity in youth with spastic CP, GMFCS levels I-IV...
January 2017: Research in Developmental Disabilities
Liesjet Van Dokkum, Emmanuelle Le Bars, Denis Mottet, Alain Bonafe, Nicolas Menjot de Champfleur, Isabelle Laffont
OBJECTIVE: After stroke, the less affected upper-limb shows slight but substantial and longterm motor deficits [1]. Kinematically, this is reflected by an increased segmentation of movements. Here, we aim to define how these changes in behavior are accompanied by changes in brain activation. MATERIAL/PATIENTS AND METHODS: Twenty-one sub-acute post-stroke patients with a first-ever unilateral ischemic stroke of the middle cerebral artery participated in this study twice: within the first 6 weeks post-stroke and after 6 weeks of rehabilitation...
September 2016: Annals of Physical and Rehabilitation Medicine
Baolei Wu, Lei Wang, Xi Yang, Ming Mao, Chen Ye, Peng Liu, Zihui Yang, Xinjie Yang, Delin Lei, Chenping Zhang
Mesenchymal stem cells (MSCs), which are physiologically maintained in vascular endothelial cell (VEC)-based niches, play a critical role in tissue regeneration. Our previous studies demonstrated that sympathetic denervation could promote MSC mobilization, thereby enhancing bone formation in distraction osteogenesis (DO), a self-tissue engineering for craniofacial and orthopeadic surgeries. However, the mechanisms on how sympathetic neurotransmitter norepinephrine (NE) regulates MSC migration are not well understood...
December 10, 2016: Experimental Cell Research
Hagit Berdishevsky, Victoria Ashley Lebel, Josette Bettany-Saltikov, Manuel Rigo, Andrea Lebel, Axel Hennes, Michele Romano, Marianna Białek, Andrzej M'hango, Tony Betts, Jean Claude de Mauroy, Jacek Durmala
In recent decades, there has been a call for change among all stakeholders involved in scoliosis management. Parents of children with scoliosis have complained about the so-called "wait and see" approach that far too many doctors use when evaluating children's scoliosis curves between 10° and 25°. Observation, Physiotherapy Scoliosis Specific Exercises (PSSE) and bracing for idiopathic scoliosis during growth are all therapeutic interventions accepted by the 2011 International Society on Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT)...
2016: Scoliosis and Spinal Disorders
Nietiayurk Aminake Ghislain, Ji-Nan Wei, Yong-Gang Li
INTRODUCTION: The meniscus is a biconcave fibrocartilage in the knee joint interpose between the femoral condyles and tibial plateau; the meniscus has functions in load bearing, load transmission, shock absorption joint stability, joint lubrication, and joint congruity. AIM: The aim of this study is to provide orthopeadic surgeon a base of reference in the choice of the optimal course of management for meniscal tears. MATERIALS AND METHODS: One hundred and seventeen patients met the criteria of inclusion for the present study...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
Kemeng Gong, Shuxin Qu, Yumei Liu, Jing Wang, Yongchao Zhang, Chongxi Jiang, Ru Shen
Ultra-high molecular weight polyethylene (UHMWPE) loaded with alendronate sodium (ALN) has tremendous potential as an orthopeadic biomaterial for joint replacements. However, poor mechanical and tribological properties of UHMWPE-ALN are still obstacle for further application. The purpose of this study was to investigate the effect and mechanism of mechanical activation on mechanical and tribological properties of 1wt% ALN-loaded UHMWPE (UHMWPE-ALN-ma). In this study, tensile test, small punch test and reciprocating sliding wear test were applied to characterize the mechanical and tribological properties of UHMWPE-ALN-ma...
August 2016: Journal of the Mechanical Behavior of Biomedical Materials
Liangming Zhang, Ruiqiang Chen, Bin Liu, Wei Zhang, Yeqing Zhu, Limin Rong
PURPOSE: Using MR imaging, nerve root sedimentation sign (SedSign) was demonstrated to have a high sensitivity and specificity for diagnosis of symptomatic lumbar spinal stenosis (LSS) in selected patients. This study was to evaluate the diagnostic value of SedSign in differential diagnosis of LSS and non-specific low back pain (LBP) in consecutive patients. METHODS: A series of consecutive patients with lumbar spinal MRI examination for back/leg pain in orthopeadic clinic were included...
October 2017: European Spine Journal
Feyzan Ozdal Kurt, H Seda Vatansever
Stem cells are classified by their tissue source. Embryonic stem cells that derived from inner cell mass of blastocyst stage embryos are highly proliferative in their undifferentiated state. A multipotent type of mesenchymal stem cells isolated from different type of tissues such as bone marrow, fat tissue etc. The dynamics of embryonic and adult stem cell cycles are profoundly dissimilar than the culture of stem cells. After improving the culture conditions and differentiation potentials, differentiated stem cells are the first cells to be preferred in modern regenerative medicine and tissue engineering...
March 31, 2015: Current Stem Cell Research & Therapy
Michał T W von Grabowski
In the paper the health-care of physically disabled patients in Germany before, during and after the II world war are discussed. The circumstances of introduction of "Racial-Hygiene" - laws and orthopedic indications for the sterilization and euthanasia are described. Patients with severe physical and mental disabilities were potential candidates for annihilation. The tragic fate of jewish physicians is remembered. The activity of board of the German Orthopeadic Society (DOG) in the years 1933-1945 is described and critically analysed...
January 2015: Ortopedia, Traumatologia, Rehabilitacja
Piotr Melzer, Maciej Głowacki, Jakub Głowacki, Ewa Misterska
The aim of the study was to evaluate the knee joint function in adolescent patients following operative treatment - fixation via arthroscopic or open surgery (arthrotomy), due to tibial eminence fractures. 28 patients, aged from 7 to 16 years, treated operatively between 1994-2009 in four orthopeadic centres underwent evaluation. Evaluation was performed 12-180 months following surgery. Patients were divided into two groups depending on the operative treatment received. Group A consisted of 14 patients who underwent arthroscopic reduction and stabilization...
2014: Acta of Bioengineering and Biomechanics
Oliver Sartor, Robert Coleman, Sten Nilsson, Daniel Heinrich, Svein I Helle, Joe M O'Sullivan, Sophie D Fosså, Aleš Chodacki, Paweł Wiechno, John Logue, Anders Widmark, Dag Clement Johannessen, Peter Hoskin, Nicholas D James, Arne Solberg, Isabel Syndikus, Nicholas J Vogelzang, C Gillies O'Bryan-Tear, Minghua Shan, Øyvind S Bruland, Christopher Parker
BACKGROUND: Bone metastases frequently cause skeletal events in patients with metastatic castration-resistant prostate cancer. Radium-223 dichloride (radium-223) selectively targets bone metastases with high-energy, short-range α-particles. We assessed the effect of radium-223 compared with placebo in patients with castration-resistant prostate cancer and bone metastases. METHODS: In this phase 3, double-blind, randomised ALSYMPCA trial, we enrolled patients who had symptomatic castration-resistant prostate cancer with two or more bone metastases and no known visceral metastases, who were receiving best standard of care, and had previously either received or were unsuitable for docetaxel...
June 2014: Lancet Oncology
Marcin Mikulewicz, Tomasz Ogiński, Thomas Gedrange, Adam Berniczei-Royko, Elżbieta Prussak
BACKGROUND: Cleft lip and/or palate is the most frequent congenital abnormality occurring in the craniofacial region and is often associated with numerous dental defects such as tooth agenesis, supernumerary teeth, microdontia, taurodontism, crown malformations, or delay in eruption. The prevalence of hypodontia in cleft-affected patients is much higher in comparison with a healthy population. The aim of this study was to evaluate the prevalence of second premolar hypodontia in patients with cleft lip and/or palate...
2014: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
C Lüring, A Freund, S Kirschner, K-P Günther, J Malzahn, C Günster, M Tingart, K-D Heller, F-U Niethard
BACKGROUND: One of the biggest health insurance companies in Germany (AOK, Allgemeine Ortskrankenkasse) has published new results focussing on process quality of total knee replacement in 2010. These results were published in the online portal "Weiße Liste", which is based on health insurance routine data. The German Association of Orthopeadic Surgery questions the credibility of the rating system of the "Weiße Liste". To prove the system an interdisciplinary task force was created...
August 2013: Zeitschrift Für Orthopädie und Unfallchirurgie
Wenjie Zhang, Guocheng Wang, Yan Liu, Xiaobing Zhao, Duohong Zou, Chao Zhu, Yuqin Jin, Qingfeng Huang, Jian Sun, Xuanyong Liu, Xinquan Jiang, Hala Zreiqat
Both surface chemistry and topography have significant influence on good and fast osseointegration of biomedical implants; the main goals in orthopeadic, dental and maxillofacial surgeries. A surface modification strategy encompassing the use of bioactive trace elements together with surface micron/nano-topographical modifications was employed in this study in an attempt to enhance the osseointegration of Ti alloy (Ti-6Al-4V), a commonly used implant. Briefly, we developed strontium-substituted hardystonite (Sr-HT) ceramic coating with a hierarchical topography where the nanosized grains were superimposed in the micron-rough coating structure...
April 2013: Biomaterials
E Fernandez, P Gastaldi
The hip and its disorders represent a clinical, diagnostic and therapeutic challenge greater than any other joints. Clinical symptoms are usually non specific and provocative maneuvers are sometimes unreliable, pain might be referred even from other joints and many times accurate assessment need imaging techniques. New surgical options, especially the latest development of hip arthroscopy has open horizons for treating intraarticular disorders. In this review article we will review basic clinical assessment and what we need as orthopeadic surgeons from radiology...
December 2012: European Journal of Radiology
Rita Kiss
The purpose of this study was to investigate the influence of sport, age and different orthopeadical diseases on the variability of gait. 45 healthy, young subjects, 11 professional hand ball players, 24 patients after medial meniscectomy, 20 elderly, healthy subjects, and 20 patients with hip osteoarthritis were examined. The average, the standard deviation and the normalized deviation of spatial and temporal parameters were calculated for each person examined and in each group. Our data suggested that the normalized deviation of parameters enables the modelling of dynamic perception, because it is independent of parameter values due to normalization...
2010: Acta of Bioengineering and Biomechanics
M Lutonský
In the submitted paper the author describes the surgical indication scheme in deformities of the metacarpophalangeal joint of the long fingers caused by rheumatoid arthritis, as used at the Orthopeadic Clinic, Faculty Hospital, Hradec Králové. The author evaluated a group of patients treated in 1984-1996 where a total of 43 joints were operated. The mean time interval after surgery was 3.5 years. As compared with the world literature, comparable results were achieved, the only complication was a dislocation of the endoprosthesis Rubena II in one patient during the postoperative period...
1997: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
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