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Yellow fever

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https://www.readbyqxmd.com/read/28646879/discovery-of-a-single-male-aedes-aegypti-l-in-merseyside-england
#1
Thom Dallimore, Tony Hunter, Jolyon M Medlock, Alexander G C Vaux, Ralph E Harbach, Clare Strode
BACKGROUND: The mosquito Aedes aegypti (L.) is found in tropical and sub-tropical regions where it is the major vector of dengue fever, yellow fever, chikungunya and more recently Zika virus. Given its importance as a vector of arboviruses and its propensity to be transported to new regions, the European Centre for Disease Prevention and Control (ECDC) has placed Ae. aegypti on a list of potentially invasive mosquito species. It was previously reported in the United Kingdom (UK) in 1865 and 1919 but did not establish on either occasion...
June 24, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28646858/reasons-for-encounter-by-different-levels-of-urgency-in-out-of-hours-emergency-primary-health-care-in-norway-a-cross-sectional-study
#2
Guttorm Raknes, Steinar Hunskaar
BACKGROUND: Frequencies of reasons for encounter (RFEs) in emergency primary care out-of-hours (OOH) services are relevant for planning of capacities as well as to target the training of staff at casualty clinics. We aimed to present frequencies of RFEs in the different organ systems, and to identify the most frequent RFEs at different urgency levels. METHODS: We analyzed data on RFEs in Norwegian OOH services. International Classification of Primary Care (ICPC-2) RFE codes were recorded in all contacts to eight representative OOH casualty clinics in 2014 and 2015 covering 20 municipalities with a total population of 260 196...
June 24, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/28643507/yellow-fever-vaccine-who-position-on-the-use-of-fractional-doses-%C3%A2-june-2017
#3
(no author information available yet)
No abstract text is available yet for this article.
June 23, 2017: Relevé épidémiologique Hebdomadaire
https://www.readbyqxmd.com/read/28638845/detection-of-the-northeastern-african-rift-valley-fever-virus-lineage-during-the-2015-outbreak-in-mauritania
#4
Ndeye Sakha Bob, Hampâté Bâ, Gamou Fall, Elkhalil Ishagh, Mamadou Y Diallo, Abdourahmane Sow, Pape Mbacké Sembene, Ousmane Faye, Brahim El Kouri, Mohamed Lemine Sidi, Amadou Alpha Sall
BACKGROUND: Rift Valley fever (RVF) is an acute viral anthropozoonosis that causes epizootics and epidemics among livestock population and humans. Multiple emergences and reemergences of the virus have occurred in Mauritania over the last decade. This article describes the outbreak that occurred in 2015 in Mauritania and reports the results of serological and molecular investigations of blood samples collected from suspected RVF patients. METHODS: An RVF outbreak was reported from 14 September to 26 November 2015 in Mauritania...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28637753/structural-mimicry-of-the-dengue-virus-envelope-glycoprotein-revealed-by-the-crystallographic-study-of-an-idiotype-anti-idiotype-fab-complex
#5
Yee Hwa Wong, Boon Chong Goh, She Yah Lim, En Wei Teo, Angeline P C Lim, Pete C Dedon, Brendon J Hanson, Paul A MacAry, Julien Lescar
A detailed understanding of the fine specificity of serotype-specific human antibodies is vital for the development and evaluation of new vaccines for pathogenic Flaviviruses such as Dengue virus (DENV) and Zika virus. In this study, we thoroughly characterize the structural footprint of an anti-idiotype antibody (E1) specific for a potent, fully human DENV serotype 1-specific antibody termed HM14c10, derived from a recovered patient. The crystal structure at a resolution of 2.5 Å of a complex between the Fab fragments of E1 and HM14c10 provides the first detailed molecular comparison of an anti-idiotype paratope specific for a human antibody with its analogous epitope- a discontinuous quaternary structure located at the surface of the viral particle that spans adjacent envelope (E) proteins...
June 21, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28630112/rapid-evolution-of-ovarian-biased-genes-in-the-yellow-fever-mosquito-aedes-aegypti
#6
Carrie A Whittle, Cassandra G Extavour
Males and females exhibit highly dimorphic phenotypes, particularly in their gonads, which is believed to be driven largely by differential gene expression. Typically, the protein sequences of genes upregulated in males, or male-biased genes, evolve rapidly as compared to female-biased and unbiased genes. To date, the specific study of gonad-biased genes remains uncommon in metazoans. Here, we identified and studied a total of 2,927, 2,013 and 4,449 coding-sequences (CDS) with ovary-biased, testis-biased and unbiased expression respectively in the yellow-fever mosquito Aedes aegypti The results showed that ovary-biased and unbiased CDS had higher nonsynonymous to synonymous substitution rates (dN/dS) and lower optimal codon usage (those codons that promote efficient translation) than testis-biased genes...
June 19, 2017: Genetics
https://www.readbyqxmd.com/read/28623054/detection-of-yellow-fever-virus-genomes-from-four-imported-cases-in-china
#7
Shujuan Cui, Yang Pan, Yanning Lyu, Zhichao Liang, Jie Li, Yulan Sun, Xiangfeng Dou, Lili Tian, Da Huo, Lijuan Chen, Xinyu Li, Quanyi Wang
Yellow fever virus (YFV), as the first proven human-pathogenic virus, is still a major public health problem with a dramatic upsurge in recent years. This is a report on four imported cases of yellow fever virus into China identified by whole genome sequencing. Phylogenetic analysis was performed and the results showed that these four viruses were highly homologous with Angola 71 strains (AY968064). In addition, effective mutations of amino acids were not observed in the E protein domain of four viruses, thus confirming the effectiveness of the YFV-17D vaccine (X03700)...
June 13, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28619415/international-travelers-sociodemographic-health-and-travel-characteristics-an-italian-study
#8
Gianmarco Troiano, Astrid Mercone, Alessandra Bagnoli, Nicola Nante
BACKGROUND: Approximately the 8% of travelers requires medical care, with the diagnosis of a vaccine-preventable disease. The aim of our study was to analyze the socio-demographic, health and travel characteristics of the Italian international travelers. METHODS: We conducted a cross sectional study from January 2015 to June 2016, at the Travel Medicine Clinic of Siena, asking the doctor to interview patients who attended the Clinic, recording socio-demographic and travel information, malaria prophylaxis, vaccinations...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28616878/lichen-striatus-following-yellow-fever-vaccination-in-an-adult-woman
#9
M Karouni, M Kurban, O Abbas
No abstract text is available yet for this article.
June 14, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28614526/yellow-fever
#10
EDITORIAL
Helio Arthur Bacha, Gustavo Henrique Johanson
No abstract text is available yet for this article.
April 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28604296/thomas-a-apel-feverish-bodies-enlightened-minds-science-and-the-yellow-fever-controversy-in-the-early-american-republic-stanford-ca-stanford-university-press-2016-pp-x-191-60-hardback-isbn-%C3%A2-9780804797405
#11
https://www.readbyqxmd.com/read/28600148/yellow-fever-importation-to-china-a-failure-of-pre-and-post-travel-control-systems
#12
EDITORIAL
Patricia Schlagenhauf, Lin H Chen
No abstract text is available yet for this article.
June 13, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28591405/genome-analysis-of-yellow-fever-virus-of-the-ongoing-outbreak-in-brazil-reveals-polymorphisms
#13
Myrna C Bonaldo, Mariela Martínez Gómez, Alexandre Ac Dos Santos, Filipe Vieira Santos de Abreu, Anielly Ferreira-de-Brito, Rafaella Moraes de Miranda, Marcia Gonçalves de Castro, Ricardo Lourenço-de-Oliveira
The current yellow fever outbreak in Brazil is the most severe one in the country in recent times. It has rapidly spread to areas where YF virus (YFV) activity has not been observed for more than 70 years and vaccine coverage is almost null. Here, we sequenced the whole YFV genome of two naturally infected howler-monkeys (Alouatta clamitans) obtained from the Municipality of Domingos Martins, state of Espírito Santo, Brazil. These two ongoing-outbreak genome sequences are identical. They clustered in the 1E sub-clade (South America genotype I) along with the Brazilian and Venezuelan strains recently characterised from infections in humans and non-human primates that have been described in the last 20 years...
June 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28577363/international-workshop-on-insecticide-resistance-in-vectors-of-arboviruses-december-2016-rio-de-janeiro-brazil
#14
Vincent Corbel, Dina M Fonseca, David Weetman, João Pinto, Nicole L Achee, Fabrice Chandre, Mamadou B Coulibaly, Isabelle Dusfour, John Grieco, Waraporn Juntarajumnong, Audrey Lenhart, Ademir J Martins, Catherine Moyes, Lee Ching Ng, Kamaraju Raghavendra, Hassan Vatandoost, John Vontas, Pie Muller, Shinji Kasai, Florence Fouque, Raman Velayudhan, Claire Durot, Jean-Philippe David
Vector-borne diseases transmitted by insect vectors such as mosquitoes occur in over 100 countries and affect almost half of the world's population. Dengue is currently the most prevalent arboviral disease but chikungunya, Zika and yellow fever show increasing prevalence and severity. Vector control, mainly by the use of insecticides, play a key role in disease prevention but the use of the same chemicals for more than 40 years, together with the dissemination of mosquitoes by trade and environmental changes, resulted in the global spread of insecticide resistance...
June 2, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28577343/de-novo-rna-synthesis-catalyzed-by-the-zika-virus-rna-polymerase-domain
#15
Christina Calmels, Michel Ventura, Cindy Aknin, Mathieu Métifiot, Marie-Line Andreola
Mosquito- and tick-borne pathogens including Chikungunya, Dengue, Japanese encephalitis, West Nile, Yellow fever and Zika virus, represent a new economic and public health challenge. In the absence of effective vaccines and specific therapies, only supportive regimens are administrated for most of these infections. Thus, the development of a targeted therapy is mandatory to stop the rapid progression of these pathogens and preoccupant associated burdens such as Guillain-Barre syndrome, microcephaly. For this, it is essential to develop biochemical tools to help study and target key viral enzymes involved in replication such as helicase complexes, methyl-transferases and RNA-dependent RNA polymerases...
June 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28574621/prospects-for-induction-of-cd8-t-cell-mediated-immunity-to-zika-virus-infection-by-yellow-fever-virus-yfv-vaccination
#16
Kim Blom, John Tyler Sandberg, Karin Loré, Hans-Gustaf Ljunggren
The Zika virus epidemic represents an unprecedented health crisis affecting significant parts of the world (1) . On February 1(st) 2016, the WHO declared the reported clusters of Zika-virus induced microcephaly and other neurological disorders a Public Health Emergency of International Concern (PHEIC). The epidemic is currently ongoing in Latin America and the Caribbean, with impacts of the infection already seen in large populations of Brazil, Colombia, Mexico, Peru and beyond. No specific treatment or vaccine is available, although several candidates are under development (2) ...
June 2, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28573234/evaluation-of-antibacterial-antitumor-antioxidant-activities-and-phenolic-constituents-of-field-grown-and-in-vitro-grown-lysimachia-vulgaris-l
#17
Arzu Birinci Yildirim, Birgul Guner, Fatma Pehlivan Karakas, Arzu Ucar Turker
BACKGROUND: Lysimachia vulgaris L. (Yellow loosestrife) is a medicinal plant in the family Myrsinaceae. It has been used in the treatment of fever, ulcer, diarrhea and wounds in folk medicine. It has also analgesic, expectorant, astringent and anti-inflammatory activities. Two different sources of the plant (field-grown and in vitro-grown) were used to evaluate the biological activities (antibacterial, antitumor and antioxidant) of L. vulgaris. In vitro-grown plant materials were collected from L...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28562637/identification-of-diagnostic-peptide-regions-that-distinguish-zika-virus-from-related-mosquito-borne-flaviviruses
#18
Alexandra J Lee, Roshni Bhattacharya, Richard H Scheuermann, Brett E Pickett
Zika virus (ZIKV) is a member of the Flavivirus genus of positive-sense single-stranded RNA viruses, which includes Dengue, West Nile, Yellow Fever, and other mosquito-borne arboviruses. Infection by ZIKV can be difficult to distinguish from infection by other mosquito-borne Flaviviruses due to high sequence similarity, serum antibody cross-reactivity, and virus co-circulation in endemic areas. Indeed, existing serological methods are not able to consistently differentiate ZIKV from other Flaviviruses, which makes it extremely difficult to accurately calculate the incidence rate of Zika-associated Guillain-Barre in adults, microcephaly in newborns, or asymptomatic infections within a geographical area...
2017: PloS One
https://www.readbyqxmd.com/read/28562615/screening-test-for-neutralizing-antibodies-against-yellow-fever-virus-based-on-a-flavivirus-pseudotype
#19
Séverine Mercier-Delarue, Christine Durier, Nathalie Colin de Verdière, Jean-Dominique Poveda, Vincent Meiffrédy, Maria Dolores Fernandez Garcia, Stéphane Lastère, Raymond Césaire, Jean-Claude Manuggera, Jean-Michel Molina, Ali Amara, François Simon
Given the possibility of yellow fever virus reintroduction in epidemiologically receptive geographic areas, the risk of vaccine supply disruption is a serious issue. New strategies to reduce the doses of injected vaccines should be evaluated very carefully in terms of immunogenicity. The plaque reduction test for the determination of neutralizing antibodies (PRNT) is particularly time-consuming and requires the use of a confinement laboratory. We have developed a new test based on the use of a non-infectious pseudovirus (WN/YF17D)...
2017: PloS One
https://www.readbyqxmd.com/read/28560654/newer-vaccines-against-mosquito-borne-diseases
#20
Anju Aggarwal, Neha Garg
Mosquitos are responsible for a number of protozoal and viral diseases. Malaria, dengue, Japanese encephalitis (JE) and chikungunya epidemics occur commonly all over the world, leading to marked mortality and morbidity in children. Zika, Yellow fever and West Nile fever are others requiring prevention. Environmental control and mosquito bite prevention are useful in decreasing the burden of disease but vaccination has been found to be most cost-effective and is the need of the hour. RTS,S/AS01 vaccine is the first malaria vaccine being licensed for use against P...
May 31, 2017: Indian Journal of Pediatrics
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