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Yellow fever

Manoj Kumar Das, M Rajesh Kumar Rao, A K Kulsreshtha
Background & objectives: Mosquitoes are responsible for transmitting several diseases, including malaria, dengue, chikungunya, filariasis, and yellow fever, etc. Release of larvivorous fishes is one of the cheapest method of vector management approach, with long suppression of mosquito population. The present study identifies the native larvivorous fishes and evaluates their potential larvivoracity for biological control of mosquito larvae in an endemic malarious region. Methods: During the year 2012-13, an ecological descriptive study was carried out in diverse aquatic habitats of fish species found in different areas of Ranchi district, in Jharkhand state of India...
January 2018: Journal of Vector Borne Diseases
Qiang Ding, Jenna M Gaska, Florian Douam, Lei Wei, David Kim, Metodi Balev, Brigitte Heller, Alexander Ploss
The limited host tropism of numerous viruses causing disease in humans remains incompletely understood. One example is Zika virus (ZIKV), an RNA virus that has reemerged in recent years. Here, we demonstrate that ZIKV efficiently infects fibroblasts from humans, great apes, New and Old World monkeys, but not rodents. ZIKV infection in human-but not murine-cells impairs responses to agonists of the cGMP-AMP synthase/stimulator of IFN genes (cGAS/STING) signaling pathway, suggesting that viral mechanisms to evade antiviral defenses are less effective in rodent cells...
June 18, 2018: Proceedings of the National Academy of Sciences of the United States of America
Glorijoy Se Tan, Monica Chan, Poh Lian Lim
No abstract text is available yet for this article.
May 2018: Annals of the Academy of Medicine, Singapore
Vanesa Rodríguez Fernández, Carlos Nicolás López Ramón Y Cajal, Elena Marín Ortiz, Emilio Couceiro Naveira
OBJECTIVE: To determine the intrapartum and perinatal results associated with different degrees of staining of meconium stained amniotic fluid (MSAF). STUDY DESIGN: In a retrospective cohort study of all singleton deliveries over a period of one year (2015) in a tertiary hospital, we compared different degrees of MSAF (yellow, green and thick) to clear amniotic fluids, and analysed in each group maternal, intrapartum and neonatal variables as well as umbilical cord blood gas analysis...
March 20, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
(no author information available yet)
A series of outbreaks of yellow fever has triggered the need for a global response. Tatum Anderson reports.
June 1, 2018: Bulletin of the World Health Organization
Alan D T Barrett
Zika virus (ZIKV), a mosquito-borne flavivirus, was first identified in the 1940s in Uganda in Africa and emerged in the Americas in Brazil in May 2015. In the 30 months since ZIKV emerged as a major public health problem, spectacular progress has been made with vaccine development cumulating with the publication of three reports of phase 1 clinical trials in the 4th quarter of 2017. Clinical trials involving candidate DNA and purified inactivated virus vaccines showed all were safe and well-tolerated in the small number of volunteers and all induced neutralizing antibodies, although these varied by vaccine candidate and dosing regimen...
2018: NPJ Vaccines
Maximiliano Ricardo Fiquepron
The goal of this article is to analyze the different representations of health and disease associated with the epidemics of yellow fever and cholera that took place from 1867-1871 in the city of Buenos Aires. It argues that there was a very broad and heterogeneous repertoire of representations that resulted in a variety of attitudes on the part of individuals dealing with the crisis, and led to the transformation of space and social time. In order to handle this traumatic experience, people chose very different methods for maintaining social contact, which was also a way of maintaining their health...
April 2018: História, Ciências, Saúde—Manguinhos
Raphaëlle Klitting, Ernest A Gould, Christophe Paupy, Xavier de Lamballerie
The recent resurgence of yellow fever virus (YFV) activity in the tropical regions of Africa and South America has sparked renewed interest in this infamous arboviral disease. Yellow fever virus had been a human plague for centuries prior to the identification of its urban transmission vector, the Aedes ( Stegomyia ) aegypti (Linnaeus) mosquito species, and the development of an efficient live-attenuated vaccine, the YF-17D strain. The combination of vector-control measures and vaccination campaigns drastically reduced YFV incidence in humans on many occasions, but the virus never ceased to circulate in the forest, through its sylvatic invertebrate vector(s) and vertebrate host(s)...
June 8, 2018: Genes
Philipp Mathé, Daniel Z Egah, Janis A Müller, Nathan Y Shehu, Emmanuel T Obishakin, David D Shwe, Victor C Pam, Mark O Okolo, Christopher Yilgwan, Simji S Gomerep, Jonas Fuchs, Ibrahim Abok, Kenneth I Onyedibe, Ewa J Olugbo, Samson E Isa, Salamatu S Machunga-Mambula, Caleb J Attah, Jan Münch, Stephen Oguche, Marcus Panning
BACKGROUND: Zika virus (ZIKV) has been known for decades in Africa but contemporary data is lacking at large. OBJECTIVES: To describe the seroepidemiology of ZIKV in North Central Nigeria. STUDY DESIGN: We performed a cross-sectional study at six health care facilities in North Central Nigeria from January to December 2016. Detection of ZIKV antibodies was done using an anti-ZIKV recombinant non-structural protein 1 (NS1)-based ELISA. A colorimetric assay to detect ZIKV neutralizing antibodies was used on ELISA reactive and randomly selected ELISA non-reactive samples...
May 26, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
Taylor Z Mann, Lisa B Haddad, Tonya R Williams, Susan L Hills, Jennifer S Read, Deborah L Dee, Eric J Dziuban, Janice Pérez-Padilla, Denise J Jamieson, Margaret A Honein, Carrie K Shapiro-Mendoza
BACKGROUND: Since the Zika virus epidemic in the Americas began in 2015, Zika virus transmission has occurred throughout the Americas. However, limited information exists regarding possible risks of transmission of Zika virus and other flaviviruses through breast feeding and human milk. We conducted a systematic review of the evidence regarding flaviviruses detection in and transmission through milk, specifically regarding Zika virus, Japanese encephalitis virus, tick-borne encephalitis virus, Powassan virus, West Nile virus, dengue virus, and yellow fever virus...
June 8, 2018: Paediatric and Perinatal Epidemiology
Christiane Costa-Pereira, Ana Carolina Campi-Azevedo, Jordana Grazziela Coelho-Dos-Reis, Vanessa Peruhype-Magalhães, Márcio Sobreira Silva Araújo, Lis Ribeiro do Vale Antonelli, Cristina Toscano Fonseca, Jandira Aparecida Lemos, Luiz Cosme Cote Malaquias, Matheus de Souza Gomes, Laurence Rodrigues Amaral, Maria Rios, Caren Chancey, Harold Richard Persi, Jorge Marcelo Pereira, Maria de Lourdes de Sousa Maia, Marcos da Silva Freire, Reinaldo de Menezes Martins, Akira Homma, Marisol Simões, Anna Yoshida Yamamura, Roberto Henrique Guedes Farias, Alessandro Pecego Martins Romano, Carla Magda Domingues, Pedro Luiz Tauil, Pedro Fernando Costa Vasconcelos, Iramaya Rodrigues Caldas, Luiz Antônio Camacho, Andrea Teixeira-Carvalho, Olindo Assis Martins-Filho
In this investigation, machine-enhanced techniques were applied to bring about scientific insights to identify a minimum set of phenotypic/functional memory-related biomarkers for post-vaccination follow-up upon yellow fever (YF) vaccination. For this purpose, memory status of circulating T-cells (Naïve/early-effector/Central-Memory/Effector-Memory) and B-cells (Naïve/non-Classical-Memory/Classical-Memory) along with the cytokine profile (IFN/TNF/IL-5/IL-10) were monitored before-NV(day0) and at distinct time-points after 17DD-YF primary vaccination-PV(day30-45); PV(year1-9) and PV(year10-11)...
June 2018: PLoS Neglected Tropical Diseases
Shannon E Brent, Alexander Watts, Martin Cetron, Matthew German, Moritz Ug Kraemer, Isaac I Bogoch, Oliver J Brady, Simon I Hay, Maria I Creatore, Kamran Khan
Objective: To examine the potential for international travel to spread yellow fever virus to cities around the world. Methods: We obtained data on the international flight itineraries of travellers who departed yellow fever-endemic areas of the world in 2016 for cities either where yellow fever was endemic or which were suitable for viral transmission. Using a global ecological model of dengue virus transmission, we predicted the suitability of cities in non-endemic areas for yellow fever transmission...
May 1, 2018: Bulletin of the World Health Organization
Duane J Gubler
No abstract text is available yet for this article.
May 1, 2018: Bulletin of the World Health Organization
Agustín Alvarez Costa, Paula V Gonzalez, Laura V Harburguer, Héctor M Masuh
An essential strategy to deal with mosquito-borne diseases is the control of larvae in their development sites. The mosquitoes Anopheles pseudopunctipennis (Theobald) (Diptera: Culicidae), a malaria vector, and Aedes aegypti (L.) (Diptera: Culicidae), vector of dengue, Zika, yellow fever, and chikungunya viruses, breed in very different habitats. Insecticide treatments of mosquito larvae focus mainly on their lethal effects. However, insecticide degradation or the poor dosage of larvicides will invariably lead to the sublethal exposure of a target (and nontarget) species, the nonlethal effects of these compounds may have important effects on vital insect activities, and therefore their evaluation is necessary...
June 4, 2018: Journal of Medical Entomology
Markus D Lacher, Gerhard Bauer, Brian Fury, Sanne Graeve, Emily L Fledderman, Tye D Petrie, Dane P Coleal-Bergum, Tia Hackett, Nicholas H Perotti, Ying Y Kong, William W Kwok, Joseph P Wagner, Charles L Wiseman, William V Williams
Targeted cancer immunotherapy with irradiated, granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting, allogeneic cancer cell lines has been an effective approach to reduce tumor burden in several patients. It is generally assumed that to be effective, these cell lines need to express immunogenic antigens coexpressed in patient tumor cells, and antigen-presenting cells need to take up such antigens then present them to patient T cells. We have previously reported that, in a phase I pilot study (ClinicalTrials...
2018: Frontiers in Immunology
Zheng Hua Amelia-Yap, Chee Dhang Chen, Mohd Sofian-Azirun, Van Lun Low
Human arboviral diseases transmitted by Aedes aegypti such as dengue, Zika, chikungunya and yellow fever remain global public health threats to date. Of these diseases, dengue fever is particularly prevalent in Southeast Asia. Relentless vector control efforts are performed to curtail disease transmissions through which pyrethroid insecticides are broadly used as the first line of defense to control Ae. aegypti, especially in the course of disease outbreaks. Here, we compile the largest contemporary database for susceptibility profiles and underlying mechanisms involved in Ae...
June 4, 2018: Parasites & Vectors
Sílvia R C Lopes, João L R Perin, Taiane S Prass, Sandra Maria D Carvalho, Sérgio C Lessa, José G Dórea
Objective : Vaccines are effective in controlling and eradicating infectious diseases. However, adverse events following immunization (AEFI) can occur in susceptible individuals. The objective of this study was to analyze the Brazilian AEFI database and compare eight vaccines in order to profile risks of AEFIs related to the mandated pediatric schedule of immunization, considering the age and sex of the child, type of vaccine, and reported adverse events. Methods : We analyzed the Brazilian AEFI database integrating reports between 2005 and 2010 for children less than 10-years old immunized with eight mandated vaccines: diphtheria, pertussis, tetanus, Haemophilus influenzae type b (TETRA); diphtheria, tetanus, and pertussis (DTP); Bacillus Calmette⁻Guerin (BCG); oral poliovirus vaccine (OPV); measles, mumps, and rubella (MMR); oral rotavirus vaccine (ORV); hepatitis B (HB); and yellow fever (YF)...
June 1, 2018: International Journal of Environmental Research and Public Health
Izabela Maurício de Rezende, Lívia Sacchetto, Érica Munhoz de Mello, Pedro Augusto Alves, Felipe Campos de Melo Iani, Talita Émile Ribeiro Adelino, Myrian Morato Duarte, Ana Luísa Furtado Cury, André Felipe Leal Bernardes, Tayrine Araujo Santos, Leonardo Soares Pereira, Maria Rita Teixeira Dutra, Dario Brock Ramalho, Benoit de Thoisy, Erna Geessien Kroon, Giliane de Souza Trindade, Betânia Paiva Drumond
BACKGROUND: Yellow fever (YF) is endemic in the Brazilian Amazon Basin, and sporadic outbreaks take place outside the endemic area in Brazil. Since 2016, YF epidemics have been occurring in Southeast Brazil, with more than 1,900 human cases and more than 1,600 epizooties of non-human primates (NHPs) reported until April 2018. Previous studies have demonstrated that Yellow fever virus (YFV) causing outbreaks in 2017 formed a monophyletic group. METHODOLOGY/PRINCIPAL FINDINGS: Aiming to decipher the origin of the YFV responsible for the recent epidemics, we obtained nucleotide sequences of YFV detected in humans (n = 6) and NHPs (n = 10) from Minas Gerais state during 2017-2018...
June 4, 2018: PLoS Neglected Tropical Diseases
K Renee Fister, Maeve L McCarthy, Seth F Oppenheimer
This paper develops an optimal control framework to investigate the introduction of sterile type mosquitoes to reduce the overal moquito population. As is well known, mosquitoes are vectors of disease. For instance the WHO lists, among other diseases, Malaria, Dengue Fever, Rift Valley Fever, Yellow Fever, Chikungunya Fever and Zika. [ ] The goal is to establish the existence of a solution given an optimal sterilization protocol as well as to develop the corresponding optimal control representation to minimize the infiltrating mosquito population while minimizing fecundity and the number of sterile type mosquitoes introduced into the environment per unit time...
May 30, 2018: Mathematical Biosciences
Geovanna Cristine de Souza Silva, Laura-Maria Peltonen, Lisiane Pruinelli, Henrique Yoshikazu Shishido, Gabrielle Jacklin Eler
Aedes aegypti and Aedes albopictus mosquitoes are responsible for the transmission of diseases such as dengue fever, yellow fever, chikungunya fever, zika virus fever, some of which can cause irreversible central nervous system problems and death. This study investigates what technologies are being used for combatting and monitoring the Aedes mosquitoes and to propose joining these technologies into a single and complete solution using the Smart Cities concept. A search for newscasts on Google and mobile apps in app stores were performed to identify technological solutions for combat to Aedes mosquitoes...
2018: Studies in Health Technology and Informatics
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