keyword
MENU ▼
Read by QxMD icon Read
search

Burns, wounds, diabetic wounds

keyword
https://www.readbyqxmd.com/read/29867473/traditional-uses-pharmacological-efficacy-and-phytochemistry-of-moringa-peregrina-forssk-fiori-a-review
#1
REVIEW
Annadurai Senthilkumar, Noushad Karuvantevida, Luca Rastrelli, Shyam S Kurup, Abdul J Cheruth
Moringa is a sole genus of Moringaceae family with 13 species distributed in the tropical and sub-tropical regions. Among them, Moringa peregrina is one of the species which has wide range of traditional, nutritional, industrial, and medicinal values. The plant parts are used in folk medicine for many human health care purposes including diabetes, wound healing, disinfectant, fever, constipation, muscle pains, slimness, burns, labor pain, hypertension, malaria, stomach disorder, asthma, skin problems, and to expel a retained placenta...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29862746/-the-clinical-status-and-process-of-hydrosurgery-system
#2
Fan Bi, Ruiyao Jiang, Hongyan Zhang, Yunxin Zheng, Bin Li
This paper reviews the principle and clinical application of hydrosurgery system, including the burn debridement, diabetic foot wounds debridement and other trauma debridement. Meanwhile, this paper introduces the development direction of waterjet technology. Furthermore, the safety, effectiveness and suitability can be discussed.
January 30, 2018: Zhongguo Yi Liao Qi Xie za Zhi, Chinese Journal of Medical Instrumentation
https://www.readbyqxmd.com/read/29849046/topical-small-molecule-granzyme-b-inhibitor-improves-remodeling-in-a-murine-model-of-impaired-burn-wound-healing
#3
Yue Shen, Matthew R Zeglinski, Christopher T Turner, Sheetal A Raithatha, Zhenguo Wu, Valerio Russo, Cameron Oram, Sho Hiroyasu, Layla Nabai, Hongyan Zhao, Tatjana Bozin, Kathryn Westendorf, Irina Kopko, Rachel Huang, Steve Arns, Jason Tan, Haishan Zeng, Anthony Boey, Richard Liggins, James Jaquith, Dale R Cameron, Anthony Papp, David J Granville
Granzyme B (GzmB) is a serine protease that has long been thought to function exclusively in lymphocyte-mediated apoptosis. In recent years, this paradigm has been revisited due to the recognition that GzmB accumulates in the extracellular milieu in many autoimmune and chronic inflammatory disorders, and contributes to impaired tissue remodeling due to the cleavage of extracellular matrix proteins. Knockout studies suggest that GzmB-mediated cleavage of decorin (DCN) contributes to impaired collagen fibrillogenesis and remodeling...
May 30, 2018: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/29845043/effects-of-local-use-of-insulin-on-wound-healing-in-non-diabetic-patients
#4
Mario Aurelio Martínez-Jiménez, Francisco Javier Valadez-Castillo, Jorge Aguilar-García, José Luis Ramírez-GarciaLuna, Francisco Israel Gaitán-Gaona, Mauricio Pierdant-Perez, Rodrigo Valdes-Rodríguez, Jesús Martín Sánchez-Aguilar
Background: Clinical trials have shown the positive effects of local insulin therapy in the formation of new vessels and fibrosis in acute and chronic diabetic wounds without major adverse effects. Objective: The aim of this study was to investigate the effects of local insulin use on wound healing in non-diabetic patients. Methods: A randomized, split-plot, double-blind, placebo-controlled trial was conducted. Ten non-diabetic patients with full-thickness acute wounds were recruited (5 due to trauma, 3 to burns, and 2 to pressure)...
May 2018: Plastic Surgery
https://www.readbyqxmd.com/read/29755850/three-dimensional-printing-and-cell-therapy-for-wound-repair
#5
REVIEW
Sylvia van Kogelenberg, Zhilian Yue, Jeremy N Dinoro, Christopher S Baker, Gordon G Wallace
Significance: Skin tissue damage is a major challenge and a burden on healthcare systems, from burns and other trauma to diabetes and vascular disease. Although the biological complexities are relatively well understood, appropriate repair mechanisms are scarce. Three-dimensional bioprinting is a layer-based approach to regenerative medicine, whereby cells and cell-based materials can be dispensed in fine spatial arrangements to mimic native tissue. Recent Advances: Various bioprinting techniques have been employed in wound repair-based skin tissue engineering, from laser-induced forward transfer to extrusion-based methods, and with the investigation of the benefits and shortcomings of each, with emphasis on biological compatibility and cell proliferation, migration, and vitality...
May 1, 2018: Advances in Wound Care
https://www.readbyqxmd.com/read/29734114/the-early-signaling-pathway-of-live-yeast-cell-derivative-in-thp-1-monocytes
#6
Eric I Gruenstein, Donna J Schlemm, Mridula Bethi, Stephen J Keller
Live yeast cell derivative (LYCD) is a medicinal yeast extract that has been used in the treatment of burns, wounds and hemorrhoids for over 70 years. It has been shown to enhance the closure of skin wounds in diabetic mice by increasing inflammation, angiogenesis, formation of granulation tissue and epithelial migration. An active fraction of LYCD has been identified as a mixture of peptides ranging in size from 5 kDA to 17 kDA. Despite its widespread use over many years, understanding of the mechanism by which LYCD acts to effect tissue repair responses is very limited...
April 22, 2018: Cell Calcium
https://www.readbyqxmd.com/read/29733454/severe-pain-during-wound-care-procedures-a-cross-sectional-study-protocol
#7
Catherine A Fiala, Linda I Abbott, Cheryl D Carter, Stephen L Hillis, Jessica S Wolf, Meghan Schuster, Rachel Dulski, Elizabeth A Grice, Barbara A Rakel, Sue E Gardner
AIM: The aim of this study is to: 1) develop and evaluate a model to predict severe pain during wound care procedures so that high-risk patients can be targeted for specialised dressings and preventive pain control; and 2) identify biological factors associated with severe pain during wound care procedures so that novel pain control strategies can be developed. BACKGROUND: Wound care procedures such as dressing changes can cause moderate to severe pain in 74% of patients, with nearly half (36%) of all patients experiencing severe pain (rated as 8-10 on a 10-point numeric rating scale) during dressing change...
May 7, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29731432/investigation-of-the-effects-of-achillea-millefolium-extract-in-diabetic-rats-with-second-degree-burns
#8
Tulay Diken Allahverdi, Ertugrul Allahverdi, Pınar Aksu Kilicle, Hasan Ozen
Our aim was to investigate the effects of Achillea millefolium on wound healing in second-degree burns formed in diabetic rats. This study was conducted at the Kafkas University Experimental Research Center. 20 Sprague Dawley rats were divided into 2 groups. Group I (n=10 rats) was the Control group and contained the diabetic rats with burn injury. Group II (n=10 rats) was the group where burn injury was created and Achillea millefolium was administered to diabetic rats. The backs of the rats were shaved so as to include 30% of the body area...
May 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29713597/the-role-of-prp-and-adipose-tissue-derived-keratinocytes-on-burn-wound-healing-in-diabetic-rats
#9
Navid Hosseini Mansoub, Mehmet Gürdal, Elif Karadadaş, Hilal Kabadayi, Seda Vatansever, Gulinnaz Ercan
Introduction: Diabetic burn wounds and ulcers are significant complications of diabetic patients. The aim of this study is to investigate the use of platelet rich-plasma (PRP) and/or keratinocyte-like cells (KLCs) in diabetic thermal wound rat model and to evaluate EGF, FGF-2, TGF-β1, COL1α2, MCP-1 and VEGF-α as wound healing markers at gene expression level. Method: In this study, we used adipose tissue as the source of mesenchymal stem cells (MSCs) and differentiated MSCs into KLCs. KLCs were characterized and transferred to the burn areas on the dorsum of streptozotocine (STZ)-induced diabetic rats...
2018: BioImpacts: BI
https://www.readbyqxmd.com/read/29691339/outbreak-of-invasive-wound-mucormycosis-in-a-burn-unit-due-to-multiple-strains-of-mucor-circinelloides-f-circinelloides-resolved-by-whole-genome-sequencing
#10
Dea Garcia-Hermoso, Alexis Criscuolo, Soo Chan Lee, Matthieu Legrand, Marc Chaouat, Blandine Denis, Matthieu Lafaurie, Martine Rouveau, Charles Soler, Jean-Vivien Schaal, Maurice Mimoun, Alexandre Mebazaa, Joseph Heitman, Françoise Dromer, Sylvain Brisse, Stéphane Bretagne, Alexandre Alanio
Mucorales are ubiquitous environmental molds responsible for mucormycosis in diabetic, immunocompromised, and severely burned patients. Small outbreaks of invasive wound mucormycosis (IWM) have already been reported in burn units without extensive microbiological investigations. We faced an outbreak of IWM in our center and investigated the clinical isolates with whole-genome sequencing (WGS) analysis. We analyzed M. circinelloides isolates from patients in our burn unit (BU1, Hôpital Saint-Louis, Paris, France) together with nonoutbreak isolates from Burn Unit 2 (BU2, Paris area) and from France over a 2-year period (2013 to 2015)...
April 24, 2018: MBio
https://www.readbyqxmd.com/read/29683361/human-recombinant-epidermal-growth-factor-in-skin-lesions-77-cases-in-epitelizando-project
#11
Jordi Esquirol-Caussa, Elisabeth Herrero-Vila
OBJECTIVE: To analyze compounded recombinant human epidermal growth factor (rhEGF) effectiveness on skin lesions through a case series. DESIGN: Multicentric series of skin lesions treated with topical rhEGF. Site: Patients from 56 different health professionals, three different countries, and two recruitment years. PARTICIPANTS: Seventy-seven patients with skin lesions, mean age of 63.15 years (min = 18, max = 95); 53.2% of patients were men and 46...
May 10, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29664823/incidence-of-cellulitis-in-lower-extremity-burns-6-year-analysis
#12
Joseph N Batac, Roger L Simpson, Catherine J Sinnott, Michael P Catanzaro, Laurence T Glickman
INTRODUCTION: Patients with burn wounds of the lower extremities are at increased risk of developing cellulitis. The probability of developing burn-associated cellulitis is presumed to be correlated with a medical history of diabetes, the etiology of the burn, delay in hospitalization of the patient during their initial presentation, and depth of the burn itself. This study aims to identify factors that place patients at increased risk for developing lower extremity burn wound cellulitis...
April 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29618862/acetic-acid-dressings-finding-the-holy-grail-for-infected-wound-management
#13
Kapil S Agrawal, Anup Vidyadhar Sarda, Raghav Shrotriya, Manoj Bachhav, Vinita Puri, Gita Nataraj
Background: Wounds have since long, contributed majorly to the health-care burden. Infected long-standing non-healing wounds place many demands on the treating surgeon and are devastating for the patients physically, nutritionally, vocationally, financially, psychologically and socially. Acetic acid has long been included among agents used in the treatment of infected wounds. In this study, we have evaluated the use of acetic acid for topical application in the treatment of infected wounds...
September 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29592981/burn-aggravated-infected-wart-in-a-patient-with-type-2-diabetes-a-medical-challenge
#14
Tahseen Ahmed Khan, Mahmood Sheikh, Iqbal Azher, Abdul Khaliq Sheikh
An infectious wart of foot in a patient with diabetics is a medical challenge, and it gets worse when aggravated with burns. We present a case of a 67-year-old Pakistani man, diabetic for 20 years presented at our healthcare centre. While awaiting his culture sensitivity report, he was prescribed an empiric antibiotic therapy. Patient then travelled to Saudi Arabia for pilgrimage 3 days later with growth of Staphylococcus aureus and Proteus species in culture and sensitivity report; during his travel, he walked barefoot and the infected wart aggravated with severe burn...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29574036/prognostic-scoring-system-for-patients-undergoing-reconstructive-foot-and-ankle-surgery-for-charcot-neuroarthropathy-the-charcot-reconstruction-preoperative-prognostic-score
#15
David Rettedal, Alissa Parker, Adam Popchak, Patrick R Burns
Charcot neuroarthropathy is a destructive process that occurs in patients with peripheral neuropathy, often due to poorly controlled diabetes mellitus. Surgical reconstruction can be necessary to provide a plantigrade foot that is wound free. A risk of major amputation exists after a Charcot event and after attempted reconstruction. We retrospectively reviewed the data from 34 patients (36 reconstructions) who had undergone reconstructive surgery for Charcot neuroarthropathy. The mean patient age was 56.44 years...
May 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29489530/use-of-flir-one-smartphone-thermography-in-burn-wound-assessment
#16
Erica Y Xue, Laurel K Chandler, Stephen L Viviano, Jonathan D Keith
OBJECTIVE: Forward-looking infrared (FLIR) thermography technology uses a handheld camera that measures skin infrared emissivity, captures photographs, and can be analyzed through specialized software. Forward-looking infrared images can be used to analyze and correlate burn wound temperature with burn depth, burn progression, and the number of days needed for healing. FLIR ONE is a miniature, smartphone-compatible thermal imaging camera that has been used to assess inflammation in diabetic foot ulcers, as well as locating perforators in flap surgery...
April 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29419365/meek-micrografting-history-indications-technique-physiology-and-experience-a-review-article
#17
Eduardo Camacho Quintero, Jesús Francisco Escrivá Machado, Roger Andres Damian Robles
AIMS: Traumatic loss of skin, particularly in major burns, requires skin grafting to repair the tissue. For a large burn, where donor sites are limited, the skin graft may need to be expanded. In addition, rapid wound closure is a large factor in successful recovery and is usually achieved by debridement and skin grafting. Micrografting was introduced by Meek and involved dividing the skin into small pieces, allowing for up to a tenfold skin expansion. METHODS: We conducted a review of the literature, searched via Medline, Pubmed and Embase (from 1958 to June 2017), searching to identify studies and reports of micrografting...
February 1, 2018: Journal of Wound Care
https://www.readbyqxmd.com/read/29406300/a-retrospective-cost-minimization-analysis-of-disposable-and-traditional-negative-pressure-wound-therapy-medicare-paid-claims
#18
Gary Delhougne, Christopher Hogan, Kim Tarka, Sunitha Nair
Traditional negative pressure wound therapy (NPWT) systems are considered durable. The pump is designed for use by numerous patients over a period of several years. Recently developed smaller, disposable devices are designed for single-patient use. A retrospective analysis of 2012-2014 national Medicare claims data was used to examine payments associated with the use of traditional and disposable NPWT systems. Data extracted included NPWT episodes from the Limited Data Set Standard Analytic Files including the 5% sample for traditional NPWT and 100% sample for disposable NPWT...
January 2018: Ostomy/wound Management
https://www.readbyqxmd.com/read/29394972/extended-islanded-reverse-sural-artery-flap-for-staged-reconstruction-of-foot-defects-proximal-to-toes
#19
Muhammad Amin Yousaf, Zain Ul Abidin, Kamran Khalid, Ata Ul Haq, Farrukh Aslam Khalid, Faraz Ahmad Tarar, Muhammad Umar Asif, Moazzam Nazeer Tarar
Obective:To assess the outcome of extended delayed reverse sural artery flap for reconstruction of foot defects proximal to toes in terms of flap survival, complication and extended area. STUDY DESIGN: Case series. PLACE AND DURATION OF STUDY: Jinnah Burn and Reconstructive Surgery Centre, Lahore, from February 2015 to April 2017. METHODOLOGY: Cases who underwent delayed sural artery flap were inducted. Preoperative hand-held doppler was done to confirm the location of perforator...
February 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29368069/effect-of-low-level-laser-therapy-on-the-healing-process-of-donor-site-in-patients-with-grade-3-burn-ulcer-after-skin-graft-surgery-a-randomized-clinical-trial
#20
Reza Vaghardoost, Mahnoush Momeni, Nooshafarin Kazemikhoo, Soheila Mokmeli, Mostafa Dahmardehei, Fereshteh Ansari, Mohammad Ali Nilforoushzadeh, Parisa Sabr Joo, Sara Mey Abadi, Soheila Naderi Gharagheshlagh, Saeed Sassani
Skin graft is a standard therapeutic technique in patients with deep ulcers, but managing donor site after grafting is very important. Although several modern dressings are available to enhance the comfort of donor site, using techniques that accelerate wound healing may enhance patient satisfaction. Low-level laser therapy (LLLT) has been used in several medical fields, including healing of diabetic, surgical, and pressure ulcers, but there is not any report of using this method for healing of donor site in burn patients...
January 24, 2018: Lasers in Medical Science
keyword
keyword
25960
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"