keyword
MENU ▼
Read by QxMD icon Read
search

BMD

keyword
https://www.readbyqxmd.com/read/29908297/prevention-of-breast-cancer-treatment-induced-bone-loss-in-premenopausal-women-treated-with-zoledronic-acid-final-5-year-results-from-the-randomized-double-blind-placebo-controlled-probone-ii-trial
#1
Ioannis Kyvernitakis, Peter Herbert Kann, Friederike Thomasius, Olaf Hars, Peyman Hadji
PURPOSE: Premenopausal women receiving chemotherapy or endocrine treatment for early breast cancer are at increased risk for cancer treatment induced bone loss (CTIBL). The aim of the randomized, double-blind ProBONE II trial was to investigate whether a 2-year adjuvant treatment with 4 mg intravenous zoledronic acid (ZOL) every 3 months versus placebo would prevent CTIBL after a five-year period. METHODS: Thirty-one of the 34 participants in the ZOL arm and thirty-four of the 36 participants in the placebo arm were followed-up to the 5-year visit and completed the study as planned...
June 13, 2018: Bone
https://www.readbyqxmd.com/read/29907149/changes-in-bone-mineral-density-after-total-parathyroidectomy-without-autotransplantation-in-the-end-stage-renal-disease-patients-with-secondary-hyperparathyroidism
#2
Li Fang, Jining Wu, Jing Luo, Ping Wen, Mingxia Xiong, Jinlong Cao, Xiaolan Chen, Junwei Yang
BACKGROUND: The patients with secondary hyperparathyroidism (SHPT) usually had reduced bone mineral density, which might lead to a substantial increase in osteoporosis, fracture and mortality. Although surgical intervention is effective in reducing parathyroid hormone (PTH) levels in suitable candidates refractory to medical therapy, the effect of surgery on bone mass changes still requires further evaluation. Thus, the aim of this study was to evaluate the characteristics of BMD changes after total parathyroidectomy (PTX) without autotransplantation and its associated factors...
June 15, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29905969/vitamin-d-supplementation-in-elderly-black-women-does-not-prevent-bone-loss-a-randomized-controlled-trial
#3
John F Aloia, Melissa Fazzari, Shahidul Islam, Mageda Mikhail, Subhashini Katumuluwa, Ruban Dhaliwal, Alexandra Stolberg, Gianina Usera, Louis Ragolia
Black Americans have lower levels of serum 25(OH)D but superior bone health compared to white Americans. There is controversy over whether they should be screened for vitamin D deficiency and have higher vitamin D requirements than recommended by the Institute of Medicine (IOM). The purpose of this trial was to determine whether Vitamin D supplementation in elderly black women prevents bone loss. 260 healthy black American women, 60 years of age and older were recruited to take part in a two arm, double-dummy 3 year RCT of vitamin D3 vs...
June 15, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29905968/skeletal-consequences-of-nephropathic-cystinosis
#4
Pablo Florenzano, Carlos Ferreira, Galina Nesterova, Mary Scott Ramnitz, Sri Harsha Tella, Luis Fernandez de Castro, Sydney M Brown, Adom Whitaker, Renata C Pereira, Dorothy Bulas, Rachel I Gafni, Isidro B Salusky, William A Gahl, Michael T Collins
Nephropathic cystinosis is a rare lysosomal storage disorder. Patients present in the first year of life with renal Fanconi syndrome that evolves to progressive chronic kidney disease (CKD). Despite the multiple risk factors for bone disease, the frequency and severity of skeletal disorders in nephropathic cystinosis have not been described. We performed systematic bone and mineral evaluations of subjects with cystinosis seen at the NIH (N = 30), including history and physical examination, serum and urine biochemistries, DXA, vertebral fracture assessment, skeletal radiographs, and renal ultrasound...
June 15, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29905044/-correlation-analysis-between-interleukin-6-polymorphism-and-adolescent-idiopathic-scoliosis-susceptibility-and-bracing-effectiveness
#5
Junsheng Gao, Lu Zhang, Zhiang Liu, Shuaihui Yao, Songming Gao
Objective: To analyze the correlation between the polymorphism on interleukin 6 (IL-6) gene promoter region-174 locus and adolescent idiopathic scoliosis (AIS), including the susceptibility, the bracing effectiveness, and the possible mechanism. Methods: The 182 AIS patients and 210 healthy controls who met the inclusion criteria between January 2013 and January 2016 were collected as research objects. The genotype of IL-6 gene promoter region-174 locus, the serum IL-6, the bone mineral density (BMD) of femoral neck and vertebrae (L 1-4 ), and the bone metabolism parameters, including bone alkaline phosphatase (BALP), bone gla protein (BGP), tartrate resistant acid phosphatase 5b (TRACP-5b), urine Ca, and urine Ca/Cr, were detected...
June 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29904824/patient-satisfaction-and-efficacy-of-switching-from-weekly-bisphosphonates-to-monthly-minodronate-for-treatment-and-prevention-of-glucocorticoid-induced-osteoporosis-in-japanese-patients-with-systemic-rheumatic-diseases-a-randomized-clinical-trial
#6
Shin-Ya Tamechika, Kaneshige Sasaki, Yoshihito Hayami, Shin-Ichiro Ohmura, Shinji Maeda, Shiho Iwagaitsu, Taio Naniwa
The randomized, clinical trial demonstrated that switching to monthly minodronate from weekly alendronate and risedronate provides greater increases in patients' satisfaction and bone mineral density and more substantial decreases in a bone resorption marker than continuing weekly alendronate and risedronate in patients with systemic rheumatic diseases on glucocorticoid therapy. PURPOSE: Osteoporosis and associated fractures are major concerns for patients with systemic rheumatic diseases on long-term glucocorticoid therapy...
June 13, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29904717/measurement-bone-mineral-density-bmd-of-patients-with-beta-thalassemia
#7
Sakineh Abbasi, Jafar Fatahi Asl, Leila Moein Zadeh, Mohammad Mirdoraghi
The aim of the study is determining bone mineral density (BMD) of Patients with beta thalassemia in order to find the prevalence and related factors on the conditions. Z -Score of femoral neck and lumbar vertebrae were reported comparing normal matched subjects. Age and bone mineral density were significantly correlated. Moreover, the disease had significantly higher severity in men than in women. A negative significant correlation was detected between BMD and the mean of hematocrit in the last 5 years. There was significant differences between sex hormone and bone density...
August 2018: Data in Brief
https://www.readbyqxmd.com/read/29904403/relationship-of-melatonin-level-oxidative-stress-and-inflammatory-status-with-osteoporosis-in-maintenance-hemodialysis-of-chronic-renal-failure
#8
Haiwei Ren, Renlian Sun, Jian Wang
The relationship of melatonin (MT) level, oxidative stress and inflammatory status with osteoporosis in the maintenance hemodialysis (MHD) of chronic renal failure was investigated. Ninety-four patients with chronic renal failure treated in Dezhou People's Hospital (Dezhoo, China) and receiving MHD for more than 3 months from May to April 2017 were selected and divided into the osteoporosis group (observation group, n=49) and the non-osteoporosis group (control group, n=45) based on whether osteoporosis was involved...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29904126/effect-of-testosterone-treatment-on-bone-remodelling-markers-and-mineral-density-in-obese-dieting-men-in-a-randomized-clinical-trial
#9
Mark Ng Tang Fui, Rudolf Hoermann, Brendan Nolan, Michelle Clarke, Jeffrey D Zajac, Mathis Grossmann
To assess the effect of testosterone treatment on bone remodelling and density in dieting obese men, 100 obese men aged 53 years (interquartile range 47-60) with a total testosterone level <12 nmol/L receiving 10 weeks of a very low energy diet (VLED) followed by 46 weeks of weight maintenance were randomly assigned at baseline to 56 weeks of intramuscular testosterone undecanoate (n = 49, cases) or matching placebo (n = 51, controls). Pre-specified outcomes were between-group differences (mean adjusted difference, MAD) in serum c-telopeptide (CTx), N-terminal propeptide of type 1 procollagen (P1NP) and bone mineral density (BMD)...
June 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29903644/high-parathyroid-hormone-levels-are-associated-with-osteosarcopenia-in-older-individuals-with-a-history-of-falling
#10
Pushpa Suriyaarachchi, Fernando Gomez, Carmen L Curcio, Derek Boersma, Lavanya Murthy, Vivian Grill, Gustavo Duque
OBJECTIVES: The combination of osteopenia/osteoporosis and sarcopenia (osteosarcopenia) defines a diagnostic subset of individuals at higher risk of falls, fractures and institutionalization. In this study we aimed to assess the potential role of high serum levels of parathyroid hormone (PTH) in osteosarcopenia. We hypothesized that a high PTH level is one of the major determinants of this syndrome. STUDY DESIGN: Cross-sectional study in 400 subjects (mean age = 79, 65% women) assessed between 2009 and 2014 at the Falls and Fractures Clinic, Nepean Hospital (Penrith, Australia)...
July 2018: Maturitas
https://www.readbyqxmd.com/read/29902356/low-bone-mineral-density-and-associated-factors-in-patients-with-haemophilia-in-colombia
#11
C L Sossa Melo, E A Wandurraga, A M Peña, S I Jiménez, L A Salazar, M E Ochoa, M L Luna-Gonzalez, M L Ortiz, K Morales, M Ayala-Castillo, D L Reyes, C M Chalela
INTRODUCTION: Patients with haemophilia may have lower levels of bone mineral density (BMD) compared with the general population. Moreover, haemophilic patients have increased risk factors for low bone mineral density (LBMD) such as arthropathy and resulting immobility, increasing their risk for osteoporosis and fractures. AIM: To assess the prevalence of LBMD and associated risk factors among a group of Colombian haemophilic patients. METHODS: In this case-control study, 90 patients with haemophilia A and B, over the age of five, were recruited...
June 14, 2018: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29901636/male-patients-with-rheumatoid-arthritis-have-an-increased-risk-of-osteoporosis-frequency-and-risk-factors
#12
Seong-Min Kweon, Dong Hyun Sohn, Ji-Heh Park, Jung Hee Koh, Eun-Kyoung Park, Han-Na Lee, Keunyoung Kim, Yunkyung Kim, Geun-Tae Kim, Seung-Geun Lee
Most previous research investigating osteoporosis in rheumatoid arthritis (RA) has focused on female patients and there is a lack of data regarding clinical characteristics of osteoporosis in male patients with RA.The aim of this study was to compare the frequency of osteoporosis between male patients with RA and healthy patients, and to identify the risk factors for osteoporosis and low bone mineral density (BMD) in male patients with RA.We conducted a retrospective, cross-sectional study including 76 South Korean male patients with RA aged over 50 years and 76 age-matched male healthy individuals...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901507/magnetic-resonance-spectroscopy-for-evaluating-the-effect-of-pulsed-electromagnetic-fields-on-marrow-adiposity-in-postmenopausal-women-with-osteopenia
#13
Shaojun Li, Hongning Jiang, Bo Wang, Mingjun Gu, Xia Bi, Ying Yin, Yu Wang
OBJECTIVE: Pulsed electromagnetic fields (PEMFs) could promote osteogenic differentiation and suppress adipogenic differentiation in bone mesenchymal stem cells ex vivo. However, data on the effect of PEMF on marrow adiposity in humans remain elusive. We aimed to determine the in vivo effect of PEMF on marrow adiposity in postmenopausal women using magnetic resonance spectroscopy. METHODS: Sixty-one postmenopausal women with osteopenia, aged 53 to 85 years, were randomly assigned to receive either PEMF treatment or placebo...
June 12, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29900589/mineral-and-bone-disorders-in-conventional-hemodialysis-challenges-and-solutions
#14
Takayuki Hamano
Despite the advent of cinacalcet and noncalcium-containing phosphate binders, controlling the progression of vascular calcification (VC) is still challenging. Recent reports demonstrate that carbamylation driven by high urea concentration aggravates VC, suggesting the importance of adequate dialysis in retarding its progression. Theoretically, other promising measures include the use of iron-based phosphate binders, vitamin K, and magnesium supplements, which should be investigated in future randomized controlled trials (RCTs), ideally with hard outcomes...
June 13, 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29900162/association-of-insulin-resistance-with-lower-bone-volume-and-strength-index-of-the-proximal-femur-in-nondiabetic-postmenopausal-women
#15
Jaewon Yang, Namki Hong, Jee-Seon Shim, Yumie Rhee, Hyeon Chang Kim
Background: Type 2 diabetes mellitus is associated with an increased risk of osteoporotic fracture despite relatively preserved bone mineral density (BMD). Although this paradox might be attributed to the influence of insulin resistance (IR) on bone structure and material properties, the association of IR with femur bone geometry and strength indices remains unclear. Methods: Using data from the Cardiovascular and Metabolic Disease Etiology Research Center cohort study, we conducted a cross-sectional analysis among nondiabetic postmenopausal women...
May 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29900159/is-sarcopenia-a-potential-risk-factor-for-distal-radius-fracture-analysis-using-propensity-score-matching
#16
Jun-Ku Lee, Byung-Ho Yoon, Chi Hoon Oh, Jung Gon Kim, Soo-Hong Han
Background: Cases of low-energy-induced distal radius fracture (DRF) are increasing. Sarcopenia is considered to be an independent risk factor for fragility fractures. We compared body appendicular lean muscle mass (ALM) and bone mineral density (BMD) in patients with DRF and a comparable control population. This study aimed to investigate the correlation between skeletal muscle mass and DRF. Methods: We performed a retrospective review of patients diagnosed with fragility DRF...
May 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29900158/high-plasma-sphingosine-1-phosphate-levels-predict-osteoporotic-fractures-in-postmenopausal-women-the-center-of-excellence-for-osteoporosis-research-study
#17
Mohammed-Salleh M Ardawi, Abdulrahim A Rouzi, Nawal S Al-Senani, Mohammed H Qari, Ayman Z Elsamanoudy, Shaker A Mousa
Background: Higher sphingosine 1-phosphate (S1P) plasma levels are associated with decreased bone mineral density (BMD), and increased risk of prevalent vertebral fracture. So, we hypothesized that postmenopausal women with increased baseline plasma S1P levels have a greater risk for future incident fracture (osteoporosis-related fractures [ORFs]). Methods: This study was conducted in a prospective longitudinal cohort of 707 women recruited in 2004 and followed up annually for a mean period of 5...
May 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29899356/the-references-level-of-cadmium-intake-for-renal-dysfunction-in-a-chinese-population
#18
Xiao Chen, Zhongqiu Wang, Guoying Zhu, Xiaoqiang Ding, Taiyi Jin
Recent several studies indicated that a more restrictive dietary intake guideline for cadmium should be made for sufficient health protection. In the present study, we showed the references level of food cadmium intake (FCd) and total cadmium intake (TCd) for renal dysfunction by using benchmark dose (BMD) approach. 342 subjects living in a control and a cadmium polluted area were included in this study. The FCd, TCd and cadmium in urine (UCd) and blood (BCd) were calculated or determined. Urinary β2 Microglobulin (UBMG) was determined as indicator of renal function...
June 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29898457/effects-of-amlodipine-on-bone-metabolism-in-orchidectomised-spontaneously-hypertensive-rats
#19
Helena Zivna, Iveta Gradošová, Pavel Zivny, Eva Cermakova, Vladimir Palicka
Spontaneously hypertensive rats (SHR) represent a model of essential hypertension. We studied the effect of amlodipine (AML) on bone markers, bone mineral density (BMD), and biomechanical properties of osteopenic bone induced by orchidectomy in male SHR. Rats were allocated to 3 groups and were sacrificed after 12 weeks: sham-operated control; orchidectomised control; and orchidectomised receiving a diet supplemented with AML. Indicators of bone turnover were assessed in bone homogenate, BMD was measured by dual energy X-ray absorptiometry, and the femurs were subjected to biomechanical testing...
June 13, 2018: Pharmacology
https://www.readbyqxmd.com/read/29898022/comparative-study-of-oral-and-salivary-parameters-in-patients-with-and-without-loss-of-bone-mass
#20
Igor Figueiredo Pereira, Cláudia Borges Brasileiro, Núbia Priscilla Kleperon, Mauro Henrique Nogueira Guimarães de Abreu, Tarcília Aparecida da Silva, Ricardo Alves Mesquita, Tania Mara Pimenta Amaral
Osteoporosis is an insidious and increasingly prevalent disease that can cause fractures and affect patients' quality of life. The current study comparatively evaluates patients with and without loss of bone mass in terms of salivary calcium, viscosity, and pH. A controlled cross-sectional study was conducted in two groups of 32 postmenopausal women subjected to a bone densitometry scan and later referred for dental management at the Federal University of Minas Gerais, Brazil. The patients were assigned to two groups: Group 1 - patients with low bone mineral density (BMD) and Group 2 - patients without bone mineral changes...
June 7, 2018: Brazilian Oral Research
keyword
keyword
2596
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"