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Mucoepidermoid carcinoma

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https://www.readbyqxmd.com/read/29343001/-pulmonary-mucoepidermoid-carcinoma-in-a-child
#1
D Xu, B L Cheng, L Wu
No abstract text is available yet for this article.
January 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29339028/overexpression-of-cdc7-in-malignant-salivary-gland-tumors-correlates-with-tumor-differentiation
#2
Zohreh Jaafari-Ashkavandi, Mohammad Javad Ashraf, Ali Asghar Abbaspoorfard
INTRODUCTION: Cell division cycle-7 protein is a serine/threonine kinase that has a basic role in cell cycle regulation and is a potential prognostic or therapeutic target in some human cancers. OBJECTIVES: This study investigated the expression of cell division cycle-7 protein in benign and malignant salivary gland tumors and also its correlation with clinicopathologic factors. METHODS: Immunohistochemical expression of cell division cycle-7 was evaluated in 46 cases, including 15 adenoid cystic carcinoma, 12 mucoepidermoid carcinoma, 14 pleomorphic adenoma, and 5 normal salivary glands...
December 26, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29338644/pulmonary-mucoepidermoid-carcinoma-diagnosis-and-treatment
#3
Neda Kalhor, Cesar A Moran
Primary mucoepidermoid carcinomas (MEC) of the lung are rare and represent a diagnostic challenge. MEC in the lung is under the umbrella of primary salivary gland type tumors of the lung. Areas Covered: In general, salivary gland type tumors are represented by malignant neoplasms that may range from low to intermediate to high-grade type of malignancy sharing similar histopathological features as those in salivary glands. The focus in this review will be on one tumor in particular - mucoepidermoid carcinoma...
January 17, 2018: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29337642/perineural-invasion-in-parotid-gland-malignancies
#4
Phillip Huyett, Umamaheswar Duvvuri, Robert L Ferris, Jonas T Johnson, Barry M Schaitkin, Seungwon Kim
Objectives To investigate the clinical predictors and survival implications of perineural invasion (PNI) in parotid gland malignancies. Study Design Case series with chart review. Setting Tertiary care medical center. Subjects and Methods Patients with parotid gland malignancies treated surgically from 2000 to 2015 were retrospectively identified in the Head and Neck Cancer Registry at a single institution. Data points were extracted from the medical record and original pathology reports. Results In total, 186 patients with parotid gland malignancies were identified with a mean follow-up of 5...
January 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29331306/primary-mucinous-eccrine-carcinoma-of-the-buccal-space-a-case-report-and-review-of-the-literature
#5
Kirkland N Lozada, Muhammed S Qazi, Azita S Khorsandi, Raymond L Chai
IMPORTANCE: Mucinous eccrine carcinoma is a rare entity that most commonly affects the head and neck. Due to its low frequency of occurrence, review of its etiology, histopathology, and treatment strategies is beneficial to all clinicians who may encounter similar appearing masses. OBSERVATION: An 84-year-old male presented with a blue mass on the left cheek. This mass started as a small bump and grew significantly over one year. His primary care physician monitored its growth and ultimately referred to an otolaryngologist...
January 5, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29313462/mucoepidermoid-carcinoma-a-23-year-experience-with-emphasis-on-low-grade-tumors-with-close-positive-margins
#6
Joseph Spellman, Gabriel Calzada
Objective Describe outcomes for mucoepidermoid carcinoma by histologic grade and evaluate outcomes for patients with low-grade tumors with close/positive margins after initial surgical resection. Study Design Cohort study. Setting Kaiser Permanente Southern California Medical Group from 1993 to 2016. Subjects and Methods Retrospective review of 154 patients with major and minor salivary gland mucoepidermoid carcinoma of the head and neck. Disease-specific and recurrence-free survival were stratified by tumor grade...
January 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29285375/expression-of-topoisomerase-ii-%C3%AE-protein-in-salivary-gland-tumors
#7
Asaf Shvero, Ohad Hilly, Golan Bubis, Yaniv Hamzany, Rumelia Koren, Lea Rath-Wolfson
Salivary glands give rise to approximately 30 histological distinct tumor types, which results in a diagnostic challenge for the pathologist. The present retrospective, immunohistochemical study aimed to evaluate the expression of Topoisomerase II-α, a nuclear enzyme, as a diagnostic and prognostic marker in benign and malignant salivary gland tumors, including leomorphic adenoma, mucoepidermoid carcinoma, acinic cell carcinoma and carcinoma ex-pleomorphic adenoma. A total of 59 cases of benign and malignant salivary gland tumors were included in the present study...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29274153/oral-cancer-a-multicenter-study
#8
K Dhanuthai, S Rojanawatsirivej, W Thosaporn, S Kintarak, A Subarnbhesaj, M Darling, E Kryshtalskyj, C-P Chiang, H-I Shin, S-Y Choi, S-S Lee, P-A Shakib
BACKGROUND: To determine the prevalence and clinicopathologic features of the oral cancer patients. MATERIAL AND METHODS: Biopsy records of the participating institutions were reviewed for oral cancer cases diagnosed from 2005 to 2014. Demographic data and site of the lesions were collected. Sites of the lesion were subdivided into lip, tongue, floor of the mouth, gingiva, alveolar mucosa, palate, buccal/labial mucosa, maxilla and mandible. Oral cancer was subdivided into 7 categories: epithelial tumors, salivary gland tumors, hematologic tumors, bone tumors, mesenchymal tumors, odontogenic tumors, and others...
December 23, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29239042/special-types-of-thyroid-carcinoma
#9
REVIEW
Zubair W Baloch, Virginia A LiVolsi
This article reviews the small percentage of thyroid tumours that are not classified as classic papillary thyroid carcinoma, follicular thyroid carcinoma, and medullary thyroid carcinoma. It includes subtypes of papillary thyroid carcinoma, including, tall-cell, hobnail/micropapillary, columnar cell, diffuse sclerosing and solid variants. Poorly differentiated carcinoma, high-grade carcinoma and anaplastic thyroid carcinoma are reviewed. Also discussed are entities that are unusual but need to be recognized as primary thyroid neoplasms, i...
January 2018: Histopathology
https://www.readbyqxmd.com/read/29238382/a-case-of-central-mucoepidermoid-carcinoma-associated-with-dentigerous-cyst
#10
Sayed Mohammad Razavi, Roya Yahyaabadi, Saeedeh Khalesi
Mucoepidermoid carcinoma (MEC) is the most common malignant salivary gland neoplasm. Central MEC (CMEC) is a rare primary intraosseous bony lesion with an incidence of 2%-4.3% of all MECs reported. In this article, we present a rare case of a CMEC in the anterior region of maxilla at a 43-year-old female patient that was arising from a dentigerous cyst. CMECs are extremely rare tumor. They are usually low-grade lesions with favorable prognosis. Odontogenic cysts are one of the origins of this lesion. Treatment of impacted tooth is necessary in the early stage for prevention of this neoplasm...
November 2017: Dental Research Journal
https://www.readbyqxmd.com/read/29231036/mucoepidermoid-carcinoma-mimicking-a-mucocele-ranula-in-the-floor-of-the-mouth
#11
Saulo L Sousa Melo, Emily Lanzel, Nitin A Pagedar, Daniah Alhazmi, Laila Dahmoush, Bruno A Policeni, Marcia S Campos
Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. The submandibular gland is rarely involved, about less than 10% of all other major salivary glands. We report a case of a 49 year-old female who presented with a mass on the left side of the floor of the mouth. She was complaining of neck pain for the last 2-3 days and had noticed the mass growing in size and becoming tender to palpation. There was no exacerbation of pain during eating, drinking or opening of mouth. A multidetector computed tomography scan was made...
December 12, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29224821/a-multicenter-study-of-malignant-oral-and-maxillofacial-lesions-in-children-and-adolescents
#12
José Alcides Almeida de Arruda, Leni Verônica de Oliveira Silva, Camila de Nazaré Alves de Oliveira Kato, Lauren Frenzel Schuch, Aline Carvalho Batista, Nádia Lago Costa, Sandra Beatriz Chaves Tarquinio, Elena Riet Correa Rivero, Vinícius Coelho Carrard, Manoela Domingues Martins, Ana Paula Veras Sobral, Ricardo Alves Mesquita
OBJECTIVES: To investigate the frequency of malignant oral and maxillofacial lesions among children and adolescents from representative geographic regions of Brazil. MATERIALS AND METHODS: A retrospective study was conducted on biopsies obtained from 1990 to 2016 at six Brazilian oral and maxillofacial pathology referral centers. A total of 85,105 biopsy specimens from children and adolescents were analyzed. Gender, age, anatomical location, symptomatology and histopathological diagnosis were evaluated...
December 2017: Oral Oncology
https://www.readbyqxmd.com/read/29204102/diagnostic-accuracy-of-touch-imprint-cytology-for-head-and-neck-malignancies-a-useful-intra-operative-tool-in-resource-limited-countries
#13
Hania Naveed, Mariam Abid, Atif Ali Hashmi, Muhammad Muzammamil Edhi, Ahmareen Khalid Sheikh, Ghazala Mudassir, Amir Khan
Background: Intraoperative consultation is an important tool for the evaluation of the upper aerodigestive tract (UAT) malignancies. Although frozen section analysis is a preferred method of intra-operative consultation, however in resource limited countries like Pakistan, this facility is not available in most institutes; therefore, we aimed to evaluate the diagnostic accuracy of touch imprint cytology for UAT malignancies using histopathology of the same tissue as gold standard. Methods: The study involved 70 cases of UAT lesions operated during the study period...
2017: BMC Clinical Pathology
https://www.readbyqxmd.com/read/29200966/microencapsulation-of-low-passage-poorly-differentiated-human-mucoepidermoid-carcinoma-cells-by-alginate-microcapsules-in-vitro-profiling-of-angiogenesis-related-molecules
#14
Sen Yang, Li-Juan Guo
Background: Human mucoepidermoid carcinoma (MEC) is regarded as the most common primary salivary malignancy. High-grade MEC has a high risk of recurrence and poor prognosis. Tumor angiogenesis, induced by poorly differentiated cancer cells of high-grade MEC, contributes to tumor growth and metastasis. Therefore, elucidating molecular mechanisms underlying the pro-angiogenic ability of poorly differentiated MEC cells is critical for the understanding of high-grade MEC progression. It is well known that three-dimensional (3D) cell culture, in contrast with conventional two-dimensional (2D) culture, provides a better approach to in vitro recapitulation of in vivo characteristics of cancer cells and their surrounding microenvironment...
2017: Cancer Cell International
https://www.readbyqxmd.com/read/29198377/central-mucoepidermoid-carcinoma-an-up-to-date-analysis-of-147-cases-and-review-of-prognostic-factors
#15
REVIEW
Lucas Lacerda de Souza, Flavia Sirotheau Correa Pontes, Helder Antonio Rebelo Pontes, Nicolau Conte Neto, Waldner Ricardo Souza de Carvalho, Douglas Magno Guimarães
OBJECTIVE: To integrate the available data published on central mucoepidermoid carcinoma (CMC) into a comprehensive analysis of its clinical aspects, histology, treatment, and prognostic factors. METHODS: An electronic search was undertaken in July 2017. Eligibility criteria for publications included having clinical, histological, treatment, and time of follow-up data to confirm the diagnosis. RESULTS: In addition, gender, histological grade, conservative treatment, and lymph node metastasis were significant independent prognostic factors...
October 31, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29185413/mucoepidermoid-carcinoma-in-a-62-year-female
#16
Betina Chandolia, Manas Bajpai, Manika Arora
No abstract text is available yet for this article.
December 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29169286/sclerosing-mucoepidermoid-carcinoma-in-the-parotid-gland-with-crtc1-maml2-fusion-a-case-report
#17
Kei Yabuki, Atsuji Matsuyama, Eisuke Shiba, Gunji Nagatani, Masanori Hisaoka
In this article, we report a case of sclerosing mucoepidermoid carcinoma (MEC) arising in the parotid gland, with CRTC1-MAML2 gene fusion. A 73-year-old woman with a mass in the right parotid region was referred to our hospital. Radiological imaging tests revealed a well-defined mass, measuring 25 mm in diameter, with foci of calcification in the deep lobe of the parotid gland, extending to the parapharyngeal space. Microscopically, the tumor was composed of a proliferation of atypical glandular epithelial cells having intracytoplasmic mucin, squamoid cells, and intermediate cells arranged in nests embedded in a fibrosclerotic stroma, associated with a dense chronic inflammatory infiltrate containing immunoglobulin G4-immunoreactive plasma cells...
November 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29144557/penile-warty-mucoepidermoid-carcinoma-with-features-of-stratified-mucin-producing-intraepithelial-lesion-and-invasive-stratified-mucin-producing-carcinoma
#18
Kenji Yorita, Naoto Kuroda, Takushi Naroda, Masato Tamura, Chisato Ohe, Mukul Divatia, Mahul B Amin, Antonio L Cubilla, Dimitry V Kazakov, Ondrej Hes, Michael Michal, Michal Michal
AIMS: Stratified mucin-producing intraepithelial lesion (SMILE) and invasive stratified mucin-producing carcinoma (ISMC) are recently described cervical and penile lesions. We report an unusual case of mixed variant of penile squamous cell carcinomas with warty, usual and mucoepidermoid SMILE/ISMC features. METHODS AND RESULTS: A 62-year-old Japanese man had a glans penis lesion of one and a half years duration, suggesting malignancy. Partial penectomy and left inguinal lymphadenectomy were performed...
November 16, 2017: Histopathology
https://www.readbyqxmd.com/read/29142456/secretory-carcinoma-impact-of-translocation-and-gene-fusions-on-salivary-gland-tumor
#19
Ryoko Inaki, Masanobu Abe, Liang Zong, Takahiro Abe, Aya Shinozaki-Ushiku, Tetsuo Ushiku, Kazuto Hoshi
Secretory carcinoma (SC), previously described as mammary analogue secretory carcinoma (MASC), is a recently described salivary gland tumor which morphologically resembles mammary secretory carcinoma. The first description of SC/MASC, reported by Skálová et al. in 2010, was as a rare salivary carcinoma imitating secretory carcinoma of the breast. SC/MASC is a unique salivary gland tumor with morphological overlap with acinic cell carcinoma (AciCC), mucoepidermoid carcinoma (MEC), and adenocarcinoma not otherwise specified (ADC-NOS)...
October 2017: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/29131467/central-mucoepidermoid-carcinoma-arising-from-glandular-odontogenic-cyst-confirmed-by-analysis-of-maml2-rearrangement-a-case-report
#20
Atsuhiro Nagasaki, Ikuko Ogawa, Yukiko Sato, Kengo Takeuchi, Masae Kitagawa, Toshinori Ando, Shinnichi Sakamoto, Madhu Shrestha, Kaori Uchisako, Koichi Koizumi, Shigeaki Toratani, Masaru Konishi, Takashi Takata
Central mucoepidermoid carcinoma (MEC) poses a diagnostic challenge because of its rarity and histological overlap with glandular odontogenic cyst (GOC). In MEC of both salivary glands and jaws, MAML2 arrangement has been well known as the specific gene alteration. We report a case of central MEC arising from GOC diagnosed by MAML2 fusion gene. A 57-year-old male presented a multilocular cystic lesion in left molar region of the mandible. Histopathologically, multiple cysts lined by thin cuboidal or non-keratinized squamous epithelium with small duct-like structures, mucous cells and ciliated cells were present...
November 13, 2017: Pathology International
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