keyword
MENU ▼
Read by QxMD icon Read
search

Frued

keyword
https://www.readbyqxmd.com/read/28100512/postexercise-repletion-of-muscle-energy-stores-with-fructose-or-glucose-in-mixed-meals
#1
Robin Rosset, Virgile Lecoultre, Léonie Egli, Jérémy Cros, Ayse Sila Dokumaci, Karin Zwygart, Chris Boesch, Roland Kreis, Philippe Schneiter, Luc Tappy
BACKGROUND: Postexercise nutrition is paramount to the restoration of muscle energy stores by providing carbohydrate and fat as precursors of glycogen and intramyocellular lipid (IMCL) synthesis. Compared with glucose, fructose ingestion results in lower postprandial glucose and higher lactate and triglyceride concentrations. We hypothesized that these differences in substrate concentration would be associated with a different partition of energy stored as IMCLs or glycogen postexercise...
January 18, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28048423/we-fg-bra-08-potential-role-of-the-glycolytic-oscillator-in-acute-hypoxia-in-tumors
#2
L Che Fru, E Adamson, D Campos, S Fain, S Jacques, A van der Kogel, K Nickel, C Song, R Kimple, M Kissick
PURPOSE: Oscillatory dynamics in acute hypoxia have been observed, but poorly understood. They have mostly been attributed to vascular perturbations, but no link has yet been made to metabolic causes. We set out to determine the fundamental frequencies and test for coherence in tumor oxygen dynamics and spatial properties. METHODS: Severe combined immunodeficient (SCID) mice were inoculated onto bilateral flanks with human derived head and neck carcinoma (UW-SCC22) cell line xenografts...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046230/we-fg-bra-03-oxygen-interplay-in-hypofractionated-radiotherapy-a-hidden-opportunity
#3
M Kissick, D Campos, V Desai, L Che Fru
PURPOSE: Local oxygen during a radiotherapy fraction has been shown to change over a full range of the oxygen enhancement ratio (OER) during the same time scale as the treatment fraction. Interplay with local oxygen is then likely a concern, especially for hypofractionation. Our experiments that show a strong role for metabolic dynamics suggesting one could manipulate this interplay for more efficacious treatments. METHODS: Two published experiments are presented with the same human head and neck cancer cell line (UM-SCC-22B)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28003715/high-fructose-intake-impairs-the-hepatic-hypolipidemic-effects-of-a-high-fat-fish-oil-diet-in-c57bl-6-mice
#4
Joshua S Wooten, Tayler N Nick, Andrew Seija, Kaylee E Poole, Kelsey B Stout
BACKGROUND: Overnutrition of saturated fats and fructose is one of the major factors for the development of nonalcoholic fatty liver disease. Because omega-3 polyunsaturated fatty acids (n-3fa) have established lipid lowering properties, we tested the hypothesis that n-3fa prevents high-fat and fructose-induced fatty liver disease in mice. METHODS: Male C57BL/6J mice were randomly assigned to one of the following diet groups for 14 weeks: normal diet (ND), high-fat lard-based diet (HFD), HFD with fructose (HFD + Fru), high-fat fish-oil diet (FOD), or FOD + Fru...
December 2016: Journal of Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/27933319/a-metabolic-widget-adjusts-the-phosphoenolpyruvate-dependent-fructose-influx-in-pseudomonas-putida
#5
Max Chavarría, Ángel Goñi-Moreno, Víctor de Lorenzo, Pablo I Nikel
Fructose uptake in the soil bacterium Pseudomonas putida occurs through a canonical phosphoenolpyruvate (PEP)-dependent sugar transport system (PTS(Fru)). The logic of the genetic circuit that rules its functioning is puzzling: the transcription of the fruBKA operon, encoding all the components of PTS(Fru), can escape the repression exerted by the catabolite repressor/activator protein Cra solely in the presence of intracellular fructose-1-P, an agonist formed only when fructose has been already transported...
November 2016: MSystems
https://www.readbyqxmd.com/read/27880074/what-does-the-fruitless-gene-tell-us-about-nature-vs-nurture-in-the-sex-life-of-drosophila
#6
Daisuke Yamamoto, Soh Kohatsu
The fruitless (fru) gene in Drosophila has been proposed to play a master regulator role in the formation of neural circuitries for male courtship behavior, which is typically considered to be an innate behavior composed of a fixed action pattern as generated by the central pattern generator. However, recent studies have shed light on experience-dependent changes and sensory-input-guided plasticity in courtship behavior. For example, enhanced male-male courtship, a fru mutant "hallmark," disappears when fru-mutant males are raised in isolation...
November 23, 2016: Fly
https://www.readbyqxmd.com/read/27864693/synthesis-and-biological-evaluation-of-a-novel-amadori-compound
#7
Giovanni N Roviello, Roberta Iannitti, Valentina Roviello, Rosanna Palumbo, Hayarpi Simonyan, Caterina Vicidomini
Here, we report the synthesis, purification, ESI MS and NMR characterization, as well as the SEM analysis of a fructosyl thiophenyl-substituted triazolyl-thione L-alanine (denominated Fru-L-TTA). This novel fructosyl derivative was obtained by solution synthesis using the Amadori reaction, in analogy to other natural fructosyl-amino acids, and fully characterized. In particular, we report an accurate NMR/MS/SEM characterization of Fru-L-TTA alongside some biological properties, and investigated to compare the properties of the artificial derivative of this work with the natural counterparts...
November 18, 2016: Amino Acids
https://www.readbyqxmd.com/read/27809666/evidence-for-view-invariant-face-recognition-units-in-unfamiliar-face-learning
#8
David B Etchells, Joseph L Brooks, Robert A Johnston
Many models of face recognition incorporate the idea of a face recognition unit (FRU), an abstracted representation formed from each experience of a face which aids recognition under novel viewing conditions. Some previous studies have failed to find evidence of this FRU representation. Here, we report three experiments which investigated this theoretical construct by modifying the face learning procedure from that in previous work. During learning, one or two views of previously unfamiliar faces were shown to participants in a serial matching task...
May 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/27668646/the-role-of-6-phosphofructo-2-kinase-pfk-2-fructose-2-6-bisphosphatase-fbpase-2-in-metabolic-reprogramming-of-cancer-cells
#9
Kinga A Kocemba, Joanna Dulińska-Litewka, Karolina L Wojdyła, Przemysław A Pękala
The high rate of glucose breakdown is the fingerprint of cancer. Increased glycolysis allows tumour cells to fulfil their high energetic and biosynthetic demands. Interestingly, however, rather than metabolizing glucose in the oxidative phosphorylation pathway, cancer cells generally use glucose for aerobic glycolysis. This phenomenon is known as the Warburg effect and is considered as one of the most fundamental forms of metabolic reprogramming during cancerogenesis. Changes in the rate of glycolytic activity of cancer cells are caused mainly by the increased expression of glycolytic enzymes as a consequence of activation of oncogenes or loss of tumour suppressors...
2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/27651579/brought-in-dead-an-avoidable-delay-in-maternal-deaths
#10
Aruna Kumar, Neha Agrawal
PURPOSE: Maternal brought in dead are the patient who dies in the need of adequate medical care. These deaths are often not analyzed sincerely as they are not institutional deaths. Our aim is to find out actual life threatening cause of delay leading to death. METHOD: Patients brought dead to casualty were seen by the doctors on duty in Department of Obstetrics and Gynaecology,Gandhi Medical College, Bhopal round the clock. Cause of death was analyzed by verbal autopsy of attendants and referral letter from the institute...
October 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27616899/antihypertensive-effect-of-korean-red-ginseng-by-enrichment-of%C3%A2-ginsenoside-rg3-and-arginine-fructose
#11
Kyung Hee Lee, In Young Bae, Song I Park, Jong-Dae Park, Hyeon Gyu Lee
BACKGROUND: Ginsenoside Rg3 and arginine-fructose (Arg-Fru) are known as the hypotensive compounds of Panax ginseng; however, their efficacy on antihypertension has not been reported yet to our best knowledge. Thus, hypotensive components-enriched fraction of red ginseng (HCEF-RG) was prepared from fine root concentrate (FR) and their antihypertensive effects were investigated in spontaneously hypertensive rats (SHR). METHODS: Male SHRs were divided into six groups: control (Wistar Kyoto, SHR); FR 500; FR 1,000; HCEF-RG 500; and HCEF-RG 1,000; samples (mg/kg body weight) were orally administered every day for 8 wk...
July 2016: Journal of Ginseng Research
https://www.readbyqxmd.com/read/27581579/jejunal-infusion-of-glucose-decreases-energy-intake-to-a-greater-extent-than-fructose-in-adult-male-rats
#12
Alexander A Moghadam, Timothy H Moran, Megan J Dailey
BACKGROUND: Intestinal nutrient infusions result in variable decreases in energy intake and body weight based on nutrient type and specific intestinal infusion site. OBJECTIVE: The objective was to test whether an intrajejunal fructose infusion (FRU) would lower energy intake and body weight and induce similar increases in gut hormones as those found after intrajejunal glucose infusions (GLU). METHODS: Male Sprague-Dawley rats received an intrajejunal infusion of either an equal kilocalorie load of glucose or fructose (11...
October 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27580166/cytokinin-regulated-sucrose-metabolism-in-stay-green-wheat-phenotype
#13
Wenqiang Wang, Qunqun Hao, Fengxia Tian, Qinxue Li, Wei Wang
A wheat stay-green mutant, tasg1, was observed to exhibit significantly delayed senescence in the late developmental stage. The photosynthetic capacity of the flag leaf was greater in tasg1 than in wild type (WT) plants. In addition, the grain volume of tasg1 was significantly higher than that of WT at the early filling stage. The content of various cytokinins (CKs) in the grain was significantly higher in tasg1 than in WT and was accompanied by an upregulated expression of some cell cycle-related genes. Examination of the metabolism of soluble sugars in tasg1 and WT revealed that the concentrations of glucose (Glu), fructose (Fru), and sucrose (Suc) were higher in the flag leaves and grains of tasg1 than in WT plants...
2016: PloS One
https://www.readbyqxmd.com/read/27568592/activation-of-latent-courtship-circuitry-in-the-brain-of-drosophila-females-induces-male-like-behaviors
#14
Carolina Rezával, Siddharth Pattnaik, Hania J Pavlou, Tetsuya Nojima, Birgit Brüggemeier, Luis A D D'Souza, Hany K M Dweck, Stephen F Goodwin
Courtship in Drosophila melanogaster offers a powerful experimental paradigm for the study of innate sexually dimorphic behaviors [1, 2]. Fruit fly males exhibit an elaborate courtship display toward a potential mate [1, 2]. Females never actively court males, but their response to the male's display determines whether mating will actually occur. Sex-specific behaviors are hardwired into the nervous system via the actions of the sex determination genes doublesex (dsx) and fruitless (fru) [1]. Activation of male-specific dsx/fru(+) P1 neurons in the brain initiates the male's courtship display [3, 4], suggesting that neurons unique to males trigger this sex-specific behavior...
September 26, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/27526941/massive-paediatric-cervicofacial-actinomycoses-masquerading-as-an-ulcerative-malignancy
#15
Carlson-Babila Sama, Nicole Fouda Mbarga, Calvin Eta Oben, Jules A Mbarga, Elvis Kiloh Nfor, Fru F Angwafo Iii
BACKGROUND: Paediatric cervicofacial actinomycosis is a rare infectious disease caused by Actinomyces spp. and usually presents as a chronic, suppurative and granulomatous inflammation with a propensity to mimic malignant conditions. CASE PRESENTATION: We discuss the case of an 11-year-old African female who presented with a chronic disfiguring cervical mass evolving over a 9 months period for which she had several unyielding consultations. Appropriate clinical and para-clinical evaluations were paramount to the diagnosis of an Actinomyces infection...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27486090/fructose-sensitizes-jurkat-cells-oxidative-stress-induced-apoptosis-via-caspase-dependent-and-caspase-independent-mechanisms
#16
Viviana Diaz-Aguirre, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio
Whether fructose (FRU), as the sole energy source, confers a metabolic advantage on cancer cells against noxious stimuli is unknown. The aim of this study was to evaluate the effects of low (11 mM), moderate (25 mM), and high (55 mM) FRU concentrations alone or in combination with rotenone (ROT) or doxorubicin (DOX) in Jurkat cells, an acute lymphoblastic leukemia cell model. Glucose (GLU) was used as a control. Using different cell analysis techniques, we demonstrated that FRU was predominantly metabolized via oxidative phosphorylation (∼95%) (i...
November 2016: Cell Biology International
https://www.readbyqxmd.com/read/27477958/the-effect-of-introducing-small-cavities-on-the-allosteric-inhibition-of-phosphofructokinase-from-bacillus-stearothermophilus
#17
Amy M Whitaker, Gregory D Reinhart
The allosteric coupling free energy between ligands fructose-6-phosphate (Fru-6-P) and phospho(enol)pyruvate (PEP) for phosphofructokinase-1 (PFK) from the moderate thermophile, Bacillus stearothermophilus (BsPFK), results from compensating enthalpy and entropy components. In BsPFK the positive coupling free energy that defines inhibition is opposite in sign from the negative enthalpy term and is therefore determined by the larger absolute value of the negative entropy term. Variants of BsPFK were made to determine the effect of adding small cavities to the structure on the allosteric function of the enzyme...
October 1, 2016: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/27418665/monitoring-glycation-induced-structural-and-biofunctional-changes-in-chicken-immunoglobulin-y-by-different-monosaccharides
#18
Zhenjiao He, Chenyao Tong, Long Sheng, Meihu Ma, Zhaoxia Cai
Chicken IgY has been applied in the food industry as an important supplement. Glycation of IgY is of special interest due to its possible influence on the structure and functionality of IgY. IgY was subjected to in vitro glycation with 4 different monosaccharides, including glucose (Glu), mannose (Man), fucose (Fuc), and fructose (Fru). The objective of this paper was to characterize the formation of IgY-sugar conjugates using ultraviolet spectra, fluorescence spectra, circular dichroism spectra, Fourier transform infrared spectra, and SDS-PAGE and differential scanning calorimetry analysis...
November 1, 2016: Poultry Science
https://www.readbyqxmd.com/read/27399765/concord-and-niagara-grape-juice-and-their-phenolics-modify-intestinal-glucose-transport-in-a-coupled-in-vitro-digestion-caco-2-human-intestinal-model
#19
Sydney Moser, Jongbin Lim, Mohammad Chegeni, JoLynne D Wightman, Bruce R Hamaker, Mario G Ferruzzi
While the potential of dietary phenolics to mitigate glycemic response has been proposed, the translation of these effects to phenolic rich foods such as 100% grape juice (GJ) remains unclear. Initial in vitro screening of GJ phenolic extracts from American grape varieties (V. labrusca; Niagara and Concord) suggested limited inhibitory capacity for amylase and α-glucosidase (6.2%-11.5% inhibition; p < 0.05). Separately, all GJ extracts (10-100 µM total phenolics) did reduce intestinal trans-epithelial transport of deuterated glucose (d7-glu) and fructose (d7-fru) by Caco-2 monolayers in a dose-dependent fashion, with 60 min d7-glu/d7-fru transport reduced 10%-38% by GJ extracts compared to control...
July 5, 2016: Nutrients
https://www.readbyqxmd.com/read/27300277/characterization-of-the-first-cultured-representative-of-verrucomicrobia-subdivision-5-indicates-the-proposal-of-a-novel-phylum
#20
Stefan Spring, Boyke Bunk, Cathrin Spröer, Peter Schumann, Manfred Rohde, Brian J Tindall, Hans-Peter Klenk
The recently isolated strain L21-Fru-AB(T) represents moderately halophilic, obligately anaerobic and saccharolytic bacteria that thrive in the suboxic transition zones of hypersaline microbial mats. Phylogenetic analyses based on 16S rRNA genes, RpoB proteins and gene content indicated that strain L21-Fru-AB(T) represents a novel species and genus affiliated with a distinct phylum-level lineage originally designated Verrucomicrobia subdivision 5. A survey of environmental 16S rRNA gene sequences revealed that members of this newly recognized phylum are wide-spread and ecologically important in various anoxic environments ranging from hypersaline sediments to wastewater and the intestine of animals...
December 2016: ISME Journal
keyword
keyword
25935
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"