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Larynx reflux

Leonardo Wanderley Lopes, Layssa Batista Simões, Jocélio Delfino da Silva, Deyverson da Silva Evangelista, Ana Celiane da Nóbrega E Ugulino, Priscila Oliveira Costa Silva, Vinícius Jefferson Dias Vieira
OBJECTIVE: This study aims to investigate the accuracy of acoustic measures in discriminating between patients with different laryngeal diagnoses. STUDY DESIGN: The study design is descriptive, cross-sectional, and retrospective. METHODS: A total of 279 female patients participated in the research. Acoustic measures of the mean and standard deviation (SD) values of the fundamental frequency (F0), jitter, shimmer, and glottal to noise excitation (GNE) were extracted from the emission of the vowel /ε/...
October 11, 2016: Journal of Voice: Official Journal of the Voice Foundation
Ivan M Lang, Bidyut K Medda, Sudarshan R Jadcherla, Reza Shaker
Stimulation of the esophagus activates the pharyngeal swallow response (EPSR) in human infants and animals. The aims of this study were to characterize the stimulus and response of the EPSR, and to determine the function and mechanisms generating the EPSR. Studies were conducted in 46 decerebrate cats in which pharyngeal, laryngeal and esophageal motility was monitored using EMG, strain gauges, or manometry. The esophagus was stimulated by balloon distension or luminal fluid infusion. We found that esophageal distension increased the chance of occurrence of the EPSR, but the delay was variable...
September 15, 2016: American Journal of Physiology. Gastrointestinal and Liver Physiology
M A Ryabova, N A Shumilova, O V Lavrova, L V Pestakova, Yu S Fedotova
The objective of the present study was to elucidate the causes responsible for a cough in the pregnant women. It involved 92 patients including 23 ones presenting with bronchial asthma and 69 having no manifestations of asthma in their medical histories but suffering from dry cough that started after the beginning of pregnancy. All the patients were given counseling by the otorhinolaryngology and pulmonology specialists. The degree of endoscopic manifestations of gastroesophageal reflux was estimated based on a scoring scale...
2016: Vestnik Otorinolaringologii
Chang Ho Hwang
Phenytoin induces lymphoid proliferation, resulting in complications that can range from tissue hyperplasia to lymphoma. Some of the complications resolve spontaneously after drug discontinuation. This report describes for the first time a case of dysphagia with lack of velopharyngeal coordination and nasopharyngeal reflux combined with massive palatine tonsillar hypertrophy. The condition did not develop before phenytoin administration, was induced by phenytoin, and spontaneously resolved upon drug discontinuation...
July 6, 2016: American Journal of Physical Medicine & Rehabilitation
Meera R Wright, Rohit Sharda, Michael F Vaezi
INTRODUCTION: Many patients experience ear, nose and throat symptoms associated with their gastroesophageal reflux disease. These symptoms are purportedly caused by reflux of gastroduodenal contents into the larynx, which leads to laryngopharyngeal reflux (LPR). Various modalities are used to diagnose LPR, including ambulatory pH monitoring, laryngoscopy, and esophagogastroduodenoscopy, as well as a few new emerging diagnostic tests. However, there are still no established diagnostic criteria or gold standard methodologies that can reliably distinguish LPR from other conditions...
September 2016: Expert Review of Gastroenterology & Hepatology
Kuen-Tze Lin, Chun-Shu Lin, Shih-Yu Lee, Wen-Yen Huang, Wei-Kuo Chang
Esophageal cancers account for majority of synchronous or metachronous head and neck cancers. This study examined the risk of esophageal cancer following percutaneous endoscopic gastrostomy (PEG) in head and neck cancer patients using the Taiwan National Health Insurance Research Database. From 1997 to 2010, we identified and analyzed 1851 PEG patients and 3702 sex-, age-, and index date-matched controls. After adjusting for esophagitis, esophagus stricture, esophageal reflux, and primary sites, the PEG cohort had a higher adjusted hazard ratio (2...
March 2016: Medicine (Baltimore)
Monika Kopka, Milena Małecka, Iwona Stelmach
Laryngopharyngeal reflux (LPR) is a complex of symptoms caused by the backflow of gastric contents into the larynx, pharynx, nasopharynx, sinuses and even to the middle ear space.The symptomatology of LPR includes: chronic cough, hoarseness, throat clearing, laryngitis,"globus pharyngeus", swallowing disturbances, postnasal drip, "fetor ex ore".In the article, the authors present two boys with chronic cough, in one of them the asthma was suspected and antiasthmatic treatment was administrated; in our patients according to the 24-hour pharyngeal pH-metry LPR was diagnosed...
2016: Pneumonologia i Alergologia Polska
Kathleen N Johnson, Daniel B Botros, Leanne Groban, Yvon F Bryan
There are many anatomical, physiopathological, and cognitive changes that occur in the elderly that affect different components of airway management: intubation, ventilation, oxygenation, and risk of aspiration. Anatomical changes occur in different areas of the airway from the oral cavity to the larynx. Common changes to the airway include tooth decay, oropharyngeal tumors, and significant decreases in neck range of motion. These changes may make intubation challenging by making it difficult to visualize the vocal cords and/or place the endotracheal tube...
2015: Clinical Interventions in Aging
Natalia Andrade, Marc Kent, Elizabeth W Howerth, MaryAnn G Radlinsky
OBJECTIVE: To evaluate pharyngeal and laryngeal function using esophagography, topical pharyngeal/laryngeal sensitivity testing, and electromyography (EMG) in normal and dogs with idiopathic laryngeal paralysis (ILP) before and after unilateral arytenoid lateralization. STUDY: Prospective controlled cohort study. ANIMALS: Dogs with laryngeal paralysis (ILP; n = 8) and age/breed-matched (AB, n = 8) and young breed-matched dogs (B, n = 8) were recruited...
November 2015: Veterinary Surgery: VS
Daniel Novakovic, Stuart MacKay
PURPOSE OF REVIEW: The review examines current evidence and thinking regarding the relationship between the larynx and obstructive sleep apnoea (OSA) in adults. RECENT FINDINGS: Drug-induced sleep endoscopy has an emerging role in the identification of laryngeal obstruction associated with sleep apnoea and may be adjunctive to awake dynamic assessment in specific cases. Nocturnal stridor and OSA is a common and treatable finding in patients with multiple system atrophy...
December 2015: Current Opinion in Otolaryngology & Head and Neck Surgery
Mmj Singendonk, B Pullens, Jaa van Heteren, Hhw de Gier, H J Hoeve, A M König-Jung, M P van der Schroeff, Cel Hoekstra, L L Veder, R J van der Pol, M A Benninga, M P van Wijk
BACKGROUND: The Reflux Finding Score for Infants (RFS-I) was developed to objectively assess signs of laryngopharyngeal reflux (LPR). Based on review of flexible laryngoscopic videos, only moderate inter- and highly variable intraobserver reliability was found. We hypothesized that examination of the infant larynx with rigid laryngoscopy would provide better agreement. AIM: to assess the validity of the RFS-I in the detection of LPR-related findings using flexible versus rigid laryngoscopy...
October 2015: Journal of Pediatric Gastroenterology and Nutrition
Francesco Martines, Pietro Salvago, Sergio Ferrara, Giuseppe Messina, Marianna Mucia, Fulvio Plescia, Federico Sireci
INTRODUCTION: Upper respiratory tract infection is a nonspecific term used to describe an acute infection involving the nose, paranasal sinuses, pharynx and larynx. Upper respiratory tract infections in children are often associated with Eustachian tube dysfunction and complicated by otitis media, an inflammatory process within the middle ear. Environmental, epidemiologic and familial risk factors for otitis media (such as sex, socioeconomic and educational factors, smoke exposure, allergy or duration of breastfeeding) have been previously reported, but actually no data about their diffusion among Sicilian children with upper respiratory tract infections are available...
March 2016: Brazilian Journal of Otorhinolaryngology
Young-Hoon Joo, Seong-Soo Lee, Kyung-do Han, Kyung-Ho Park
BACKGROUND: Chronic laryngitis (CL) has been described as chronic inflammation of the larynx. CL have various causes such as long-term smoking, acid reflux, voice overuse, bronchitis, allergies, pneumonia, excessive exposure to toxic chemicals and complications from the flu or a chronic cold. However, the prevalence of CL and role of air pollution in the etiology is uncertain. OBJECTIVE: The aim of this study was to investigate the relationship between CL and particulate matter with aerodynamic diameter less than 10 μm (PM10) in South Korea using data from the Korea National Health and Nutrition Examination Surveys (KNHANES) during 2008-2012...
2015: PloS One
Mustafa Sahin, Rukiye Vardar, Sinan Ersin, Tayfun Kirazli, M Fatih Ogut, N Serdar Akyildiz, Serhat Bor
The aim of this study was to evaluate the effect of laparoscopic antireflux surgery (LARS) on the laryngeal symptoms, physical findings and voice parameters of gastroesophageal reflux disease (GERD) patients with or without laryngopharyngeal reflux (LPR). Forty-one GERD patients predominantly with LPR symptoms (Group I) and twenty-six GERD patients without LPR symptoms (Group II) who had LARS were prospectively analysed before and 2 years after the surgery. Upper gastrointestinal endoscopy, 24-h ambulatory pH or MII-pH monitoring was performed in all cases...
November 2015: European Archives of Oto-rhino-laryngology
Tina Samuels, Craig Hoekzema, Jon Gould, Matthew Goldblatt, Matthew Frelich, Matthew Bosler, Sang-Hyuk Lee, Nikki Johnston
OBJECTIVE: Despite widespread use of proton pump inhibitors (PPIs), the incidence of esophageal adenocarcinoma (EAC) continues to rise. PPIs reduce reflux acidity, but only transiently inactivate gastric enzymes. Nonacid reflux, specifically nonacid pepsin, contributes to carcinogenesis in the larynx. Given the carcinogenic potential of pepsin and inefficacy of PPIs to prevent EAC, the presence and effect of pepsin in the esophagus should be investigated. METHODS: Normal and Barrett's biopsies from 8 Barrett's esophagus patients were collected for pepsin analysis via Western blot and reverse transcriptase-polymerase chain reaction (RT-PCR)...
November 2015: Annals of Otology, Rhinology, and Laryngology
Siniša Stevanović, Radivoje Radić, Željka Perić Kačarević, Vladimir Bedeković, Ivana Aras, Tomislav Baudoin, Dario Šoš, Zvonimir Vrselja, Mirko Ivkić
OBJECTIVE: The goal of our study was to investigate and to identify the existence of proton pump in different parts of larynx. The presence of acidic content in this area is known to be connected to several laryngeal diseases. It is mostly developed by upward recurrence of acidic gastric content, but there are some signs that the acid can be produced in the larynx as well, because of the proton pump activity in laryngeal mucosa. METHODS: The study was performed on two types of specimens: (1) 50 cadaver larynges and (2) 11 surgical larynges obtained after laryngectomy...
December 2015: Auris, Nasus, Larynx
Ivan Baljosevic, Predrag Minic, Goran Trajkovic, Gordana Markovic-Sovtic, Bojana Radojicic, Aleksandar Sovtic
BACKGROUND: Laryngomalacia (LM) is the most common congenital anomaly of larynx that causes stridor in children. We evaluated the efficacy of epiglottic suture and laser epiglottopexy for treatment of infants with severe LM. METHODS: Surgical intervention was performed in 19 patients with severe LM, after the diagnosis was established using flexible laryngotracheobronchoscopy. Five patients had isolated type 1 LM, and 14 patients had a combination of type 1 and 3 LM...
December 2015: Pediatrics International: Official Journal of the Japan Pediatric Society
Jennifer A Anderson
PURPOSE OF REVIEW: The purpose of this study is to review the relevant literature concerning work-associated irritable larynx syndrome (WILS), a hyperkinetic laryngeal disorder associated with occupational irritant exposure. Clinical symptoms are variable and include dysphonia, cough, dyspnoea and globus pharyngeus. WILS is a clinical diagnosis and can be difficult to differentiate from asthma. Treatment options for WILS include medical and behavioural therapy. RECENT FINDINGS: Laryngeal-centred upper airway symptoms secondary to airborne irritants have been documented in the literature under a variety of diagnostic labels, including WILS, vocal cord dysfunction (VCD), laryngeal hypersensitivity and laryngeal neuropathy and many others...
April 2015: Current Opinion in Allergy and Clinical Immunology
Andrea Ciorba, Chiara Bianchini, Michele Zuolo, Carlo Vittorio Feo
A wide variety of symptoms and diseases of the upper aerodigestive tract are associated to gastro-oesophageal reflux disease (GORD). These disorders comprise a large variety of conditions such as asthma, chronic otitis media and sinusitis, chronic cough, and laryngeal disorders including paroxysmal laryngospasm. Laryngo-pharyngeal reflux disease is an extraoesophageal variant of GORD that can affect the larynx and pharynx. Despite numerous research efforts, the diagnosis of laryngopharyngeal reflux often remains elusive, unproven and controversial, and its treatment is then still empiric...
February 16, 2015: World Journal of Clinical Cases
Wen-Hung Wang, Kai-Yu Tsai
OBJECTIVE: To compare the difference between white light (WL) and narrow-band imaging (NBI) endoscopy in evaluating patients who had reflux laryngitis and esophagitis. STUDY DESIGN: Retrospective review of medical records and endoscopic images. SETTING: Outpatient clinic. SUBJECTS AND METHODS: There were 102 consecutive patients with reflux esophagitis (mean age, 48 ± 11 years) who had office-based transnasal esophagoscopy (TNE) with WL and NBI views, including 60 men (59%) and 42 women (41%)...
May 2015: Otolaryngology—Head and Neck Surgery
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