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Hypospadia

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https://www.readbyqxmd.com/read/28515816/impact-of-smartphone-digital-photography-email-and-media-communication-on-emergency-room-visits-post-hypospadias-repair
#1
Michael E Chua, Megan A Saunders, Paul R Bowlin, Jessica M Ming, Roberto Iglesias Lopes, Walid A Farhat, Joana Dos Santos
INTRODUCTION: Advances in communication technology are shaping our medical practice. To date, there is no clear evidence that this mode of communication will have any effect on unnecessary postoperative emergency room (ER) visits. We aim to evaluate the effect of email and media communication with application of smartphone digital photography on post-hypospadias repair ER visit rates. METHODS: This prospective cohort study included all patients who underwent hypospadias repair performed by a single surgeon from October 2014 to November 2015...
March 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28505945/re-penile-appearance-after-hypospadias-correction-from-a-parent-s-point-of-view-comparison-of-the-hypospadias-objective-penile-evaluation-score-and-parents-penile-perception-score
#2
https://www.readbyqxmd.com/read/28505692/outcome-after-hypospadias-repair-evaluation-using-the-hypospadias-objective-penile-evaluation-score
#3
Sarah Krull, Anke Rissmann, Hardy Krause, Klaus Mohnike, Friedrich-Wilhelm Roehl, Andrea Koehn, Hans-Juergen Hass
No abstract text is available yet for this article.
May 15, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28505275/maternal-stressors-and-social-support-and-risks-of-delivering-babies-with-gastroschisis-or-hypospadias
#4
Suzan L Carmichael, Chen Ma, Sarah Tinker, Gary M Shaw
We examined the association of maternal stressful life events and social support with risks of gastroschisis and hypospadias, using data from the National Birth Defects Prevention Study, a population-based case-control study of US births taking place in 2006-2011. We examined maternal self-reports of 7 life events and 3 sources of social support during the periconceptional period among mothers of 593 gastroschisis cases, 1,142 male hypospadias cases, and 4,399 nonmalformed controls. Responses to the questions on stressful life events were summed to form an index (higher is worse), as were responses to questions on social support (higher is better)...
May 13, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28503233/single-penile-incision-for-combined-hypospadias-and-inguinal-surgery-a-comparative-study
#5
Michael E Chua, Naif Alqarni, Jessica M Ming, Fahad Alyami, Joana Dos Santos, Roberto Iglesias Lopes, Walid A Farhat, Martin A Koyle
INTRODUCTION: We sought to compare the surgical outcomes of hypospadias repair with correction of inguinal pathology using a single penile incision vs. conventional approach using two incisions. METHODS: This is a retrospective study that reviewed all patients who underwent concurrent surgical repair for both hypospadias and inguinal pathologies between January 2003 and November 2015. Patients were classified into Group A, conventional (inguinal or scrotal and penile incision) approach; or Group B, single penile incision approach...
May 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28498391/hypospadias-in-a-male-infant-with-an-unusual-mosaic-45-x-46-x-psu-idic-y-p11-32-46-xy-and-haploinsufficiency-of-shox-a-case-report
#6
Yan-Mei Si, Yuan Dong, Wei Wang, Ke-Yan Qi, Xin Wang
A male newborn presented with hypospadias and differential testicular volumes. Short femur length was detected four times during pregnancy, at 23, 31, 32 and 33 weeks, by ultrasonographic examination. Chromosome analysis was performed on peripheral lymphocytes obtained from the infant and his parents. Fluorescent in situ hybridization (FISH), using sex determining region Y (SRY)/DXZ1 and DYZ3 probes, was performed to verify the deletion of the SRY gene (located on Yp11.3 region) and the activation of Y chromosomal centromeres...
May 10, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28495506/use-of-bipedicled-dorsal-penile-flap-with-z-release-incision-a-new-option-in-redo-hypospadias-surgery
#7
Hazem Elmoghazy
OBJECTIVES: To solve the challenge in redo hypospadias surgery; we tried the use of bipedicled dorsal penile flap with Z release incision in failed hypospadias cases and reported the outcome. MATERIAL AND METHODS: Thirty male children with 3 or 4 previous unsuccessful hypospadias surgeries were included in our study. Our technique was done after at least 6 month from the last surgery. A flap of the dorsal penile skin is preserved and the skin lateral is dissected on each side...
May 8, 2017: Urology
https://www.readbyqxmd.com/read/28491817/a-45-x-46-xy-male-with-orchidopexy-diagnosed-with-mixed-germ-cell-tumor-after-21-year-follow-up
#8
Masashi Kubota, Naoki Terada, Katsuhiro Ito, Hideaki Takada, Toshihiro Magaribuchi, Atsuro Sawada, Shusuke Akamatsu, Hiromitsu Negoro, Ryoichi Saito, Takashi Kobayashi, Toshinari Yamasaki, Takahiro Inoue, Osamu Ogawa
A case of a 45,X/46,XY boy with gonadal dysgenesis is presented. The patient showed hypospadias and right undescended testis. He underwent underwent repair surgery for hypospadias, right orchidopexy, and bilateral testicular biopsy. Testicular biopsy revealed no malignant finding. He was followed-up annually by scrotum palpation. When the patient grew up to 24 years old, he was diagnosed to have right testicular tumor. High orchiectomy revealed pT1 seminoma. The management of undescended testis in men with gonadal dysgenesis and disordered sexual development is discussed...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28479764/role-of-tubularization-of-urethral-plate-in-development-of-urethrocutaneous-fistula-post-hypospadias-repair
#9
Basim S Alsaywid, Abdullah K Mohammedkhalil, Abdullah A Mesawa, Saif Y Alzahrani, Aseel H Askar, Wesam T Abuznadah, Mohamoud H Alrimawi
INTRODUCTION: This study aimed to demonstrate the outcome of hypospadias repair in the pediatric population using the tubularized urethral plate technique and to compare the incidence of fistula between incised and unincised urethral plate. METHODOLOGY: This is a retrospective cohort study of pediatric patients who had hypospadias repair in a tertiary hospital in Jeddah, Saudi Arabia, between January 2000 and December 2012. They were divided into two main groups according to the status of the urethral plate: Group A included patients who had incision of the urethral plate just before tubularization, and Group B included patients who underwent tubularization without incision...
April 2017: Urology Annals
https://www.readbyqxmd.com/read/28479404/association-of-reproductive-disorders-and-male-congenital-anomalies-with-environmental-exposure-to-endocrine-active-pesticides
#10
Jessica García González, María Isabel Ventura Miranda, Mar Requena Mullor, Antonio F Hernández Jerez, Tesifón Parrón Carreño, Raquel Alarcón Rodriguez
There is growing evidence that environmental exposure to pesticides may increase the risk of developing reproductive and developmental disorders. This study determined the prevalence and risk of developing gestational disorders and male congenital genitourinary malformations in areas with distinct exposure to pesticides, many of them with potential endocrine disrupting properties. A population-based case-control study was carried out on pregnant women and male children living in ten health districts of Andalusia classified as areas of high and low environmental exposure to pesticides according to agronomic criteria...
May 4, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28479205/commentary-to-current-challenges-with-proximal-hypospadias-we-have-a-long-way-to-go
#11
Hans G Pohl
No abstract text is available yet for this article.
April 21, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28472982/comparative-safety-of-anti-epileptic-drugs-during-pregnancy-a-systematic-review-and-network-meta-analysis-of-congenital-malformations-and-prenatal-outcomes
#12
Areti Angeliki Veroniki, Elise Cogo, Patricia Rios, Sharon E Straus, Yaron Finkelstein, Ryan Kealey, Emily Reynen, Charlene Soobiah, Kednapa Thavorn, Brian Hutton, Brenda R Hemmelgarn, Fatemeh Yazdi, Jennifer D'Souza, Heather MacDonald, Andrea C Tricco
BACKGROUND: Pregnant women with epilepsy frequently experience seizures related to pregnancy complications and are often prescribed anti-epileptic drugs (AEDs) to manage their symptoms. However, less is known about the comparative safety of AED exposure in utero. We aimed to compare the risk of congenital malformations (CMs) and prenatal outcomes of AEDs in infants/children who were exposed to AEDs in utero through a systematic review and Bayesian random-effects network meta-analysis...
May 5, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28469305/a-novel-composite-two-stage-urethroplasty-for-complex-penile-strictures-a-multicenter-experience
#13
Pankaj M Joshi, Guido Barbagli, Vikram Batra, Sandesh Surana, Atef Hamouda, Salvatore Sansalone, Dimitris Costi, Massimo Lazzeri, Craig Hunter, Devang J Desai, Fabio Castiglione, Sanjay B Kulkarni
INTRODUCTION: Complex penile strictures are usually repaired using a two-stage urethroplasty. Buccal mucosal graft (BMG) placed in the first stage can have a significant contraction rate, which may require a subsequent revision surgery. We describe a composite two-stage penile urethroplasty using BMG for patients of complex penile strictures who have some salvageable urethral plate. METHODS: Within a multi-institutional cohort, 82 patients underwent a two-stage urethroplasty for complex stricture of the penile urethra...
April 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28461997/evaluation-of-jordan-s-meatoplasty-for-the-treatment-of-fossa-navicularis-strictures-a-retrospective-study
#14
Prakash Babu, Arvind Nayak, Tarun Dilip Javali, Prarthan Joshi, Horahally Krishnareddy Nagaraj, Kuldeep Aggarwal
INTRODUCTION: Fossa navicular strictures can be a challenging problem for reconstructive urologists in which there is a need to achieve good cosmetic results along with a consistent stream. Our aim was to retrospectively evaluate the outcome of Jordan meatoplasty in the management of fossa navicularis strictures. MATERIAL AND METHODS: A total of 25 patients who underwent Jordan meatoplasty for the management of fossa navicularis strictures between 2011 and 2016 were retrospectively reviewed...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28454986/old-tools-old-problems-new-solution-the-use-of-a-modified-cecil-culp-concept-in-the-trauma-setting
#15
Dana A Weiss, Zachary L Smith, Jesse Taylor, Douglas A Canning
A 12-year-old boy sustained a close-range shotgun wound with buckshot to the penis and lower abdomen. The proximal two-thirds of the corpora cavernosa were obliterated, and the distal third was thrombosed. All dorsal penile skin was lost. The urethra remained intact. The patient underwent multiple debridements, allowing the wound to declare its borders. Employing the tissue transfer concept used by Cecil and Culp in hypospadias repairs, the penis was marsupialized onto the suprapubic area where it remained for 8 months...
April 25, 2017: Urology
https://www.readbyqxmd.com/read/28436366/analysis-of-preoperative-antibiotic-prophylaxis-in-stented-distal-hypospadias-repair
#16
Jacob Smith, Ashay Patel, Ismael Zamilpa, Shasha Bai, Jeffrey Alliston, Stephen Canon
INTRODUCTION: Surgical site infection [SSI] is a risk for any surgical procedure, including hypospadias repair. Prophylactic antibiotic therapy for patients having surgery is often effective in preventing SSIs, but with increasing rates of antibiotic resistance, this practice has been questioned. The objectives of this study are 1) to assess the incidence of SSIs in patients following stented, distal hypospadias repair and 2) to observe for any potential difference in the incidence of SSIs for patients with and without preoperative antibiotic utilization in this setting...
April 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28434637/clinical-heterogeneity-in-children-with-gonadal-dysgenesis-associated-with-non-mosaic-46-xy-karyotype
#17
Y S Wong, Y H Tam, K K Y Pang, K F To, S S C Chan, K W Chan, K H Lee
INTRODUCTION: Gonadal dysgenesis is unique in disorders of sex development (DSD), in that it can be associated with 46,XX, 46,XY or mosaic 45,X/46,XY karyotypes. Gonadal dysgenesis can be partial or complete. Gonadal dysgenesis associated with the Y-chromosome has increased risk of gonadal germ cell neoplasms. Most of the literature focus on 45,X/46,XY gonadal dysgenesis, while there are scanty data on the condition when the karyotype is non-mosaic 46,XY. OBJECTIVE: To investigate the diversity of clinical pictures of children presenting with 46,XY DSD due to gonadal dysgenesis...
April 10, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28434634/hypospadias-surgery-in-england-higher-volume-centres-have-lower-complication-rates
#18
David J Wilkinson, Patrick A Green, Shanthi Beglinger, Jessica Myers, Rachel Hudson, David Edgar, Simon E Kenny
INTRODUCTION: Hypospadias surgery has progressed steadily over recent years. There remains considerable variation in the operative management of boys with hypospadias in the UK, and it is therefore difficult to identify acceptable standards with regards to reoperation rates. OBJECTIVE: To determine the frequency of reoperations and complications from all centres performing hypospadias surgery in England and to identify variables that influence outcome. METHODS: All children undergoing NHS hypospadias surgery in England between 1999 and 2009 were identified using the Hospital Episode Statistics database...
February 20, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28434633/echocardiographic-evaluation-of-left-ventricular-mass-index-in-children-with-hypospadias-after-hormonal-stimulation-with-topical-testosterone-a-randomized-controlled-trial
#19
Elisabeth Campos de Andrade, Kelly Christina de Castro Paiva, Sarah da Silva Guedes, Mariana Lima C Souza, Marina Novellino Pereira, Laura Pimenta Miana, André Avarese de Figueiredo, José de Bessa, José Murillo B Netto
INTRODUCTION: Testosterone is often used in the preoperative period of hypospadias surgery. Previous studies have demonstrated the presence of androgen receptors in cardiac myocytes that can modulate the phenotype. The use of supraphysiological doses of androgens can lead to toxicity on the heart muscle and, in some cases, to left ventricular hypertrophy. This randomized double blind controlled clinical trial aims to evaluate the effect of topical testosterone on left ventricular mass index in boys with hypospadias...
April 10, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28432720/androgen-receptor-dysfunction-as-a-prevalent-manifestation-in-young-male-carriers-of-a-flna-gene-mutation
#20
Laura Carrera-García, Maximiliano Francisco Rivas-Crespo, María Soledad Fernández García
Androgenic actions require the proper signal transmission by the androgen receptor (AR), a nuclear transcription factor. This is initially located in the cell cytoplasm and should translocates to the nucleus to interact with DNA. AR functional impairment causes diverse blockage degrees of androgenic steroid action, known as androgen insensitivity syndromes. Filamin A, a protein coded by the FLNA gene, is a co-activator of various cytoplasmic factors, including AR. The mutational inactivation of the FLNA gene induces insufficiency of translocation and activation of AR...
April 21, 2017: American Journal of Medical Genetics. Part A
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