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Hypospadia

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https://www.readbyqxmd.com/read/28328642/can-we-preserve-the-urethral-plate-in-proximal-hypospadias-repair
#1
Smail Acimi, Mohammed Ali Acimi
PURPOSE: To know the limits of the preservation of the urethral plate in the correction of the curvature associated with proximal hypospadias. METHODS: From January 2002 to January 2015, we treated 224 patients of proximal hypospadias. In 182 cases, we used of the lateral pictures taken during the successive saline erection tests to measure the correction obtained after each stage. RESULTS: The analysis of the lateral pictures taken at the successive saline erection tests clearly demonstrated that release of the skin and dartos fascia provides an important correction of the chordee...
March 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28326003/effects-of-organic-food-consumption-on-human-health-the-jury-is-still-out
#2
Marcin Barański, Leonidas Rempelos, Per Ole Iversen, Carlo Leifert
The most recent systematic literature reviews and meta-analyses have indicated significant and nutritionally-relevant composition differences between organic and conventional foods. This included higher antioxidant, but lower cadmium and pesticide levels in organic crops, and higher omega-3 fatty acids concentrations in organic meat and dairy products. Also, results from a small number of human cohort studies indicate that there are positive associations between organic food consumption and reduced risk/incidence of certain acute diseases (e...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28322901/urethral-mobilization-as-an-alternative-procedure-for-distal-hypospadias-repair
#3
Hamed M El Darawany, Mahmoud E Al Damhogy
OBJECTIVE: To evaluated the urethral mobilization procedure as the main technique in management of glanular, coronal, subcoronal, and distal penile hypospadias. PATIENTS AND METHODS: Sixty patients with distal hypospadias were included in this prospective study between January 2013 and January 2015. All of them repaired by urethral mobilization. All patients were followed up at 2 weeks, 1, 3, 6 and 12 months post operatively. Duration of the operation, hospital stay, position of meatus and its shape before and after the operation and the postoperative complications were recorded...
March 17, 2017: Urology
https://www.readbyqxmd.com/read/28319024/the-prostatic-utricle-an-under-recognized-condition-resulting-in-significant-morbidity-in-boys-with-both-hypospadias-and-normal-external-genitalia
#4
Austin G Hester, Stanley J Kogan
INTRODUCTION: Pediatric presentations of a prostatic utricle have received only scant attention. Though recognized with increased frequency in boys with hypospadias, little is described about their incidence and potential for morbidity in boys with normal external genitalia. METHODS: We initially reviewed a cohort of 64 patients with hypospadias seen over a 3-year period to determine the frequency of investigative lower urinary tract studies and utricle identification...
March 1, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28315282/complications-after-hypospadias-correction-prognostic-factors-and-impact-on-final-clinical-outcome
#5
Elisabeth Maria Dokter, Chantal M Mouës, Iris A L M van Rooij, Jan Jaap van der Biezen
Purpose The purpose of this study was to analyze the influence of patient and treatment characteristics on the occurrence of complications after hypospadias correction and the impact of complications on final clinical outcome. Methods The study cohort consisted of 205 hypospadias patients who had surgery in the Medical Centre Leeuwarden (1996-2011). Patient and treatment characteristics were hypospadias severity (preoperative meatal location and chordee), number of planned surgeries, reconstruction technique, operation year, and patient's age at the time of surgery...
March 17, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28314972/-rare-diseases-with-clinical-relevance-the-silver-russell-syndrome
#6
C Neissner, C Schepp, W H Rösch
The Silver-Russell syndrome (SRS) is a rare imprinting disease associated with pre- and postnatal growth retardation, craniofacial features, and asymmetry. Genitourinary abnormalities are seen in up to 20% of affected individuals. Apart from structural renal anomalies, cryptorchidism and hypospadias occur frequently in boys, while girls often have anomalies similar to those in Mayer-Rokitansky-Küster-Hauser syndrome with congenital hypoplasia or aplasia of the uterus and upper part of the vagina. Frequently hypospadias repair and orchiopexy are difficult because of lack of buccal mucosa due to facial dysmorphism and intraabdominal position of the testicles, respectively...
March 17, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28285314/the-staged-urethroplasty-with-vascularised-scrotal-flap-and-buccal-mucosa-graft-after-failed-hypospadias-surgery-a-reliable-technique-with-a-novel-tool
#7
Abhishek Pandey, Anna-Maria Barta-Kelemen, Michael Borisenkov, Hansjörg Keller
Background/Aims/Objectives: To report the outcome of staged urethroplasty with buccal mucosa and vascularised scrotal flap after failed hypospadias surgery. METHODS: n = 35. INCLUSION CRITERIA: destroyed urethral plate, deficient local skin, fistula and penile deviation. Five out of 35 patients also had a secondary proximal stricture. Stage 1: excision of scarred tissue and fistulae, correction of the penile deviation through dorsal plication and the ventral placement and quilting of buccal graft...
March 11, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28265320/striving-to-improve-care-for-hypospadias-patients
#8
Luis H Braga
No abstract text is available yet for this article.
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28265319/current-hypospadias-management-diagnosis-surgical-management-and-long-term-patient-centred-outcomes
#9
REVIEW
Melise A Keays, Sumit Dave
In this article, we present the current approach to hypospadias, a review of the classification, preoperative evaluation, and factors that enable decision-making during surgery. We will then discuss patient-reported outcomes, evaluating the patients' and parents' perspectives regarding hypospadias repair.
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28263821/the-fisher-technique-for-correction-of-penile-torsion-in-children-who-are-the-candidates
#10
J B Marret, P Ravasse, L Raffoul, J Rod
OBJECTIVE: To report our experience in the treatment of penile torsion with a special reference to the Fisher technique. PATIENTS AND METHODS: We reviewed thirty cases of congenital penile torsion treated from 2009 to 2015 in a single center. Sixteen patients presented a moderate rotation of 45° to 90° and 14 had a severe rotation with an angle greater than 90°. Chordee was present in 17 cases and distal glanular hypospadias in 15 cases. Median age at surgery was 10 months...
March 2, 2017: Urology
https://www.readbyqxmd.com/read/28262534/use-of-a-fibrovascular-tube-in-creation-of-neo-urethra-during-penile-reconstruction
#11
Abdul Kerim Yapici, Sami Uguz, Yalcin Bayram, Sebahattin Sari, Yildirim Karslioglu, Ahmet Guven, Serdar Ozturk
INTRODUCTION: There are several techniques employed in the surgical treatment of total or partial penile reconstruction, hypospadias surgery, and urethral stricture. Urethral reconstruction is performed in different ways applying these techniques. OBJECTIVE: We evaluated use of a fibrovascular sheath to create a neo-urethra formed around a silicon tube. MATERIAL AND METHODS: We used nine male New Zealand rabbits for this study. In the first step, we placed a silicone tube under the skin in the lower abdomen of the rabbits and waited for the formation of a fibrovascular sheath to totally surround the tube...
February 20, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28261839/clinical-and-molecular-characteristics-in-15-patients-with-androgen-receptor-gene-mutations-from-south-china
#12
L Su, J Cheng, X Yin, G Liu, Z Lu, H Sheng, Y Cai, Q Shi, L Liu
A variety of mutations in the androgen receptor (AR) gene are linked to androgen insensitivity syndrome (AIS) or sexual development disorder. Here, we studied 15 patients with various degrees of disorders of genital hypoplasia from South China. Clinical data including basal hormone level, phenotype, karyotyping and SRY gene identification were documented. Exons with flanking intronic region of the AR gene were sequenced and analysed for mutations, and a total of eight mutations were identified in the AR gene...
March 6, 2017: Andrologia
https://www.readbyqxmd.com/read/28259618/commentary-to-proximal-hypospadias-repair-with-bladder-mucosal-graft-our-10-years-experience
#13
Seth A Alpert
No abstract text is available yet for this article.
February 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28259148/establishing-disability-weights-for-congenital-pediatric-surgical-conditions-a-multi-modal-approach
#14
D Poenaru, J Pemberton, C Frankfurter, B H Cameron, E Stolk
BACKGROUND: Burden of disease (BoD) as measured by Disability-Adjusted Life Years (DALYs) is one of the criteria for priority-setting in health care resource allocation. DALYs incorporate disability weights (DWs), which are currently expert-derived estimates or non-existent for most pediatric surgical conditions. The objective of this study is to establish DWs for a subset of key pediatric congenital anomalies using a range of health valuation metrics with caregivers in both high- and low-resource settings...
March 4, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28253873/extended-clinical-features-associated-with-novel-glis3-mutation-a-case-report
#15
K A Alghamdi, A B Alsaedi, A Aljasser, A Altawil, Naglaa M Kamal
BACKGROUND: Mutations in the GLI-similar 3 (GLIS3) gene encoding the transcription factor GLIS3 are a rare cause of neonatal diabetes and congenital hypothyroidism with 12 reported patients to date. Additional features, previously described, include congenital glaucoma, hepatic fibrosis, polycystic kidneys, developmental delay, facial dysmorphism, osteopenia, sensorineural deafness, choanal atresia, craniosynostosis and pancreatic exocrine insufficiency. CASE PRESENTATION: We report a new case for consanguineous parents with homozygous novel mutation in GLIS3 gene who presented with neonatal diabetes mellitus, severe resistant congenital hypothyroidism, cholestatic liver disease, bilateral congenital glaucoma and facial dysmorphism...
March 2, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28225973/do-you-know-this-syndrome-leopard-syndrome
#16
Flávio Heleno da Silva Queiroz Cançado, Luis Candido Pinto da Silva, Paulo Franco Taitson, Ana Carolina Dias Viana de Andrade, Matheus Melo Pithon, Dauro Douglas Oliveira
Hypertrophic cardiomyopathy is known as Leopard syndrome, which is a mnemonic rule for multiple lentigines (L), electrocardiographic conduction abnormalities (E), ocular hypertelorism (O), pulmonary stenosis (P), abnormalities of genitalia (A), retardation of growth (R), and deafness (D). We report the case of a 12-year-old patient with some of the abovementioned characteristics: hypertelorism, macroglossia, lentigines, hypospadias, cryptorchidism, subaortic stenosis, growth retardation, and hearing impairment...
January 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28222406/leydig-cell-clustering-and-reinke-crystal-distribution-in-relation-to-hormonal-function-in-adult-patients-with-testicular-dysgenesis-syndrome-tds-including-cryptorchidism
#17
Rikke R Soerensen, Trine H Johannsen, Niels E Skakkebaek, Ewa Rajpert-De Meyts
OBJECTIVE: Testicular dysgenesis syndrome (TDS) comprises testicular germ cell cancer, cryptorchidism and some cases of male infertility and hypospadias, which can be linked to impairment of intrauterine gonadal development. Among histological signs of TDS, large Leydig cell (LC) clusters (micronodules) are frequently present. This study aimed to investigate possible associations of LC micronodules with the presence of Reinke crystals and hormonal function of LCs, the latter primarily reflected by serum concentrations of luteinising hormone (LH) and testosterone, in patients with TDS...
October 2016: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28216923/direct-visual-internal-urethrotomy-is-it-a-durable-treatment-option
#18
Dilip Kumar Pal, Sanjay Kumar, Bastab Ghosh
OBJECTIVE: To evaluate the long-term success rate of direct vision internal urethrotomy as a treatment for anterior urethral strictures. MATERIALS AND METHODS: We retrospectively analyzed the results for patients who underwent internal urethrotomy from January 2009 to January 2014 for anterior urethral strictures. Patients were followed till January 2016. Patients with complicated urethral strictures with a history of previous urethroplasty, hypospadias repair, or previous radiation were excluded from the study, as anticipated low success rate of direct visual internal urethrotomy (DVIU) in these patients...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28215832/variation-in-the-clinical-and-genetic-evaluation-of-undervirilized-boys-with-bifid-scrotum-and-hypospadias
#19
J M Swartz, R Ciarlo, E Denhoff, A Abrha, D A Diamond, J N Hirschhorn, Y-M Chan
BACKGROUND: Bifid scrotum and hypospadias can be signs of undervirilization, yet boys presenting with these findings often do not undergo genetic evaluation. In some cases, identifying an underlying genetic diagnosis can help to optimize clinical care and improve guidance given to patients and families. OBJECTIVES: The aim of this study was to characterize current practice for genetic evaluation of patients with bifid scrotum, and to identify approaches with a good diagnostic yield...
January 30, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28213855/correction-of-residual-ventral-penile-curvature-after-division-of-the-urethral-plate-in-the-first-stage-of-a-2-stage-proximal-hypospadias-repair
#20
REVIEW
Bruce J Schlomer
PURPOSE OF REVIEW: The first stage of a 2-stage proximal hypospadias repair involves division of the urethral plate and correction of any residual ventral penile curvature (VPC). Options to correct residual VPC include dorsal corporal shortening or ventral corporal lengthening techniques. This review discusses these options and suggests an approach to management. RECENT FINDINGS: Recent reports of 2-stage proximal hypospadias repairs indicate low rates of recurrent VPC with either dorsal corporal shortening or ventral corporal lengthening...
February 2017: Current Urology Reports
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